-->
Receptor
PDB id Resolution Class Description Source Keywords
3VSE 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF METHYLTRANSFERASE STAPHYLOCOCCUS AUREUS ROSSMANN FOLD METHYLTRANSFERASE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF A PUTATIVE METHYLTRANSFERASE S FROM STAPHYLOCOCCUS AUREUS PROTEIN PEPT.LETT. V. 20 530 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH C:401;
D:401;
A:401;
B:401;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3VSE 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF METHYLTRANSFERASE STAPHYLOCOCCUS AUREUS ROSSMANN FOLD METHYLTRANSFERASE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF A PUTATIVE METHYLTRANSFERASE S FROM STAPHYLOCOCCUS AUREUS PROTEIN PEPT.LETT. V. 20 530 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3VSE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3VSE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3VSE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3VSE; Ligand: SAH; Similar sites found with APoc: 850
This union binding pocket(no: 1) in the query (biounit: 3vse.bio3) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 3OU2 SAH 0.917431
2 4TXI FAD 1.00503
3 1RM0 D6P 1.00503
4 1RM0 NAI 1.00503
5 1YKJ PHB 1.01523
6 1YKJ FAD 1.01523
7 1RJD SAM 1.1976
8 3F8D FAD 1.23839
9 1LTH NAD 1.25392
10 3QOX SAH 1.25628
11 4B63 FAD 1.25628
12 4B63 NAP 1.25628
13 4B63 ORN 1.25628
14 3T31 DCQ 1.25628
15 3T31 FAD 1.25628
16 1P31 EPU 1.25628
17 1P3D UMA 1.25628
18 4E70 N7I 1.28866
19 4Y9D NAI 1.31148
20 2EG5 SAH 1.34409
21 5Z21 NAI 1.39665
22 1BC5 SAH 1.48699
23 5MW4 5JU 1.49701
24 3S5W FAD 1.50754
25 2EFJ SAH 1.50754
26 2C7G FAD 1.50754
27 2C7G ODP 1.50754
28 5G3U FDA 1.50754
29 2WPF FAD 1.50754
30 1BZL GCG 1.50754
31 4J36 1HR 1.50754
32 1BZL FAD 1.50754
33 4J36 FAD 1.50754
34 2WPF WPF 1.50754
35 1FEC FAD 1.50754
36 2Q28 ADP 1.50754
37 2FR1 NDP 1.50754
38 3FG2 FAD 1.50754
39 1UP7 NAD 1.50754
40 5G3U ITW 1.50754
41 6F7L FAD 1.50754
42 5KKA 6V0 1.60256
43 3TKY SAH 1.63043
44 1YXM ADE 1.65016
45 1N2X SAM 1.66113
46 4DPL NAP 1.67131
47 1XHL NDP 1.6835
48 5Y8L NAD 1.69492
49 1JQD SAH 1.71233
50 2AOT SAH 1.71233
51 1JQD HSM 1.71233
52 1R37 NAD 1.72911
53 2YYY NAP 1.74927
54 1COY FAD 1.75879
55 5ZYN FAD 1.75879
56 1Q1R FAD 1.75879
57 2HQM FAD 1.75879
58 4EMI NAD 1.75879
59 4EMI FAD 1.75879
60 3E1T FAD 1.75879
61 3NDJ JHZ 1.75879
62 3NDJ SAH 1.75879
63 2RGJ FAD 1.75879
64 1COY AND 1.75879
65 5JWC FAD 1.75879
66 4RSL FAD 1.75879
67 1DLJ NAI 1.75879
68 3AYI HCI 1.75879
69 3AYI FAD 1.75879
70 1DLJ UGA 1.75879
71 2GMH FAD 1.75879
72 5EOW FAD 1.75879
73 1R27 MGD 1.75879
74 1NV8 MEQ 1.76056
75 1NV8 SAM 1.76056
76 1K27 MTM 1.76678
77 1VKO NAD 1.8622
78 5FA8 SAM 1.86335
79 5K4W THR 1.86916
80 5K4W NAI 1.86916
81 3RFV 15L 1.87266
82 3RFV NAI 1.87266
83 1RLZ NAD 1.89702
84 3WDM ADN 1.91571
85 1ZPT FAD 1.97368
86 1YBH FAD 2.01005
87 1ZK7 FAD 2.01005
88 5JAQ NAI 2.01005
89 5T67 JHZ 2.01005
90 5T67 SAH 2.01005
91 3G5S FAD 2.01005
92 1H82 FAD 2.01005
93 1H82 GZZ 2.01005
94 5U8U FAD 2.01005
95 2WET FAD 2.01005
96 5NA1 FAD 2.01005
97 3O7W SAM 2.01005
98 4U8P UDP 2.01005
99 4U8P FDA 2.01005
100 2IV2 MGD 2.01005
101 4EDF UPG 2.01005
102 1OC2 TDX 2.01149
103 1OC2 NAD 2.01149
104 1IM8 SAI 2.04918
105 5U19 SAH 2.05279
106 5U19 827 2.05279
107 6C5B SAH 2.05279
108 1UAY ADN 2.06612
109 1WG8 SAM 2.10526
110 5YJI SAH 2.11268
111 5YJI 8WO 2.11268
112 1B8O IMH 2.11268
113 4DCM SAM 2.13333
114 5ETJ IM5 2.16049
115 1GR0 NAD 2.17984
116 6ECT SAM 2.18069
117 5O42 9JW 2.18978
118 5O42 BGC 2.18978
119 5O42 NAD 2.18978
120 6F9Q NAD 2.20588
121 3AB1 FAD 2.22222
122 3QWI CUE 2.22222
123 3QWI NAP 2.22222
124 3PT9 SAH 2.26131
125 4N49 SAM 2.26131
126 1GPE FAD 2.26131
127 5WGR FAD 2.26131
128 1NAA ABL 2.26131
129 1NAA 6FA 2.26131
130 5TS5 FAD 2.26131
131 6FP4 FAD 2.26131
132 6FP4 E1T 2.26131
133 3NKS FAD 2.26131
134 2E5V FAD 2.26131
135 3SSO SAH 2.26131
136 1Z45 NAD 2.26131
137 2B9W FAD 2.26131
138 4Z24 FAD 2.26131
139 1V8B NAD 2.26131
140 5ICE SAH 2.27273
141 5ICE 2H4 2.27273
142 3GF4 FAD 2.30769
143 3GF4 UPG 2.30769
144 2AE2 PTO 2.30769
145 2AE2 NAP 2.30769
146 4PNE SAH 2.31788
147 1W73 NAP 2.31788
148 1W8D NAP 2.31788
149 3A28 NAD 2.32558
150 3ELW GP3 2.33333
151 3ELW SAM 2.33333
152 1R6D NAD 2.37389
153 1R6D DAU 2.37389
154 5F8F SFG 2.38727
155 2VHW NAI 2.38727
156 6FDF SAH 2.39521
157 1KPH SAH 2.43902
158 1ZBQ NAD 2.44648
159 1NM5 NAP 2.46305
160 1NM5 NAD 2.46305
161 5YJF 8WO 2.46479
162 5YJF SAH 2.46479
163 1C0I BE2 2.47934
164 1C0I FAD 2.47934
165 5XLX SAH 2.48227
166 5YF1 8V0 2.48619
167 5YF1 SFG 2.48619
168 1GZ6 NAI 2.50784
169 5WP4 SAH 2.51256
170 1X87 NAD 2.51256
171 4EUE NAI 2.51256
172 4MOP 2H5 2.51256
173 1YQZ FAD 2.51256
174 1V5F FAD 2.51256
175 1V5F TPP 2.51256
176 2JB2 FAD 2.51256
177 2JB2 PHE 2.51256
178 2C5A GDC 2.51256
179 2C5A NAD 2.51256
180 1LVL NAD 2.51256
181 1REO FAD 2.51256
182 5WKC FAD 2.51256
183 1T9D FAD 2.51256
184 1T9D 1MM 2.51256
185 1T9D PYD 2.51256
186 1T9D P25 2.51256
187 5XWV 8H6 2.51256
188 5XWV NDP 2.51256
189 3OND NAD 2.51256
190 3OND ADN 2.51256
191 1LVL FAD 2.51256
192 4D5G FAD 2.51256
193 4D5G TPP 2.51256
194 1MUU NAD 2.51256
195 1MV8 NAD 2.51256
196 4UP4 GAL NAG 2.51256
197 1EU1 MGD 2.51256
198 5GWT SIN 2.51799
199 5GWT NAD 2.51799
200 1BXK NAD 2.53521
201 4D79 ATP 2.53623
202 5MGZ SAH 2.54237
203 4O0L NDP 2.54545
204 3GGO ENO 2.54777
205 3GGO NAI 2.54777
206 1PN0 IPH 2.55639
207 1PN0 FAD 2.55639
208 4HA6 FAD 2.55906
209 4Y30 SAH 2.5641
210 4Y30 49L 2.5641
211 6GAR FAD 2.5788
212 2CUL FAD 2.58621
213 5ULP KB1 2.61194
214 5TWB FAD 2.61628
215 5CUQ NSC 2.62172
216 2VVM FAD 2.62626
217 2VVL FAD 2.62626
218 3PFG TLO 2.6616
219 3PFG SAM 2.6616
220 5ZW3 SAH 2.66667
221 3TLJ SAH 2.68097
222 1E3W NAD 2.68199
223 1FP1 SAH 2.68817
224 1E6W NAD 2.69231
225 5OJI ISN 2.69231
226 5OJI NAP 2.69231
227 3GRU AMP 2.71186
228 5F2K OCA 2.71739
229 5F2K SAH 2.71739
230 3ABI NAD 2.73973
231 1XTP SAI 2.75591
232 3X0D SAH 2.76382
233 3ICT FAD 2.76382
234 4KGD FAD 2.76382
235 4KGD TDP 2.76382
236 1RSG FAD 2.76382
237 3ICR FAD 2.76382
238 5X62 SAH 2.76382
239 3ICS FAD 2.76382
240 1YY5 FAD 2.76382
241 2Z3Y F2N 2.76382
242 5JJR SAH 2.76382
243 4C3Y FAD 2.76382
244 2XVF FAD 2.76382
245 4C3Y ANB 2.76382
246 6F97 FAD 2.76382
247 4RPL 3UC 2.76382
248 4RPL FAD 2.76382
249 3K7M FAD 2.76382
250 2YVF NAD 2.76382
251 2YVF FAD 2.76382
252 1KNR FAD 2.76382
253 6DEN TP9 2.76382
254 6DEN G8A 2.76382
255 6DEN FAD 2.76382
256 4K5S FAD 2.76382
257 4K5S PM0 2.76382
258 2AQJ FAD 2.76382
259 2AQJ TRP 2.76382
260 2C31 TZD 2.76382
261 2C31 ADP 2.76382
262 4YKG FAD 2.76382
263 4YKG NAD 2.76382
264 2IZ1 ATR 2.76382
265 5J7X FAD 2.76382
266 3ICT ADP 2.76382
267 3ICS ADP 2.76382
268 3OFK SAH 2.77778
269 1PNO NAP 2.77778
270 4RDH AMP 2.77778
271 4RDI ATP 2.77778
272 1TPY SAH 2.78746
273 5F7J ADE 2.8125
274 6GKV SAH 2.849
275 1I9G SAM 2.85714
276 1XG5 NAP 2.86738
277 2OOR TXP 2.87356
278 3ZNN FAD 2.88184
279 3ZNN 4WL 2.88184
280 4K26 NDP 2.89855
281 4K26 SFF 2.89855
282 2GN4 NDP 2.90698
283 2GN4 UD1 2.90698
284 2HNK SAH 2.92887
285 4YT4 FE9 2.93333
286 1XDS SAM 2.94118
287 1QZZ SAM 2.94118
288 1CF2 NAP 2.96736
289 4ITU NAI 2.97398
290 4ITU 1HS 2.97398
291 3LCC SAH 2.97872
292 3I53 SAH 3.01205
293 5WP5 SAH 3.01508
294 4BJZ FAD 3.01508
295 4BJZ P3A 3.01508
296 4D04 FAD 3.01508
297 4D04 NAP 3.01508
298 4AP3 FAD 3.01508
299 4AP3 NAP 3.01508
300 2ZJ1 ARJ 3.01508
301 2ZJ1 NAD 3.01508
302 5FWA J7C 3.01508
303 2NYA MGD 3.01508
304 3CBG SAH 3.01724
305 2PZM UDP 3.0303
306 2PZM NAD 3.0303
307 1JQ3 AAT 3.04054
308 4TXJ THM 3.04054
309 4USQ FAD 3.04709
310 1U7T TDT 3.06513
311 1U7T NAD 3.06513
312 1R18 SAH 3.0837
313 1OMO NAD 3.10559
314 1L3I SAH 3.125
315 4J7U NAP 3.125
316 4J7U YTZ 3.125
317 1KPG SAH 3.13589
318 5OJ7 AR6 3.14685
319 1ZQ9 SAM 3.15789
320 1G0N NDP 3.18021
321 1G0N PHH 3.18021
322 6GFK SAH 3.18725
323 1Z6Z NAP 3.19149
324 6DNT NAD 3.19767
325 5YU3 PRO 3.19767
326 5YU3 NAD 3.19767
327 5EIN NAP 3.19767
328 4YSX FAD 3.20513
329 2YY7 NAD 3.20513
330 1UXG FUM 3.23625
331 1UXG NAD 3.23625
332 4BV6 FAD 3.24544
333 4FC7 NAP 3.2491
334 4FC7 COA 3.2491
335 5DNK SAH 3.26633
336 4KRI SAH 3.26633
337 4X9M FAD 3.26633
338 5GSN NAP 3.26633
339 5GSN FAD 3.26633
340 3UOY FAD 3.26633
341 3UOY NAP 3.26633
342 5GSN MMZ 3.26633
343 3X0V FAD 3.26633
344 4IV9 FAD 3.26633
345 5WS9 AMP 3.26633
346 3EVG SAH 3.27273
347 5KOK SAH 3.27456
348 3OZ2 FAD 3.27456
349 5KOK S9T 3.27456
350 5KOK R9T 3.27456
351 1KYZ SAH 3.28767
352 1KYZ FER 3.28767
353 2Q1W NAD 3.3033
354 3GDH SAH 3.3195
355 3WMX NAD 3.35196
356 4ONQ SFG 3.36134
357 1A69 FMB 3.36134
358 4YAC NAI 3.367
359 5BW4 SAM 3.37079
360 3EGI ADP 3.39806
361 5GT9 NAP 3.42205
362 6C8R SAH 3.43008
363 6C8R EQV 3.43008
364 5FEU NAP 3.43643
365 4YAG NAI 3.46021
366 1E1M NAP 3.47826
367 1E1M FAD 3.47826
368 1L1E SAH 3.48432
369 4I5I NAD 3.48432
370 4FK7 P34 3.49345
371 5XNC MTA 3.50404
372 5TTJ FAD 3.51759
373 6ER9 NAP 3.51759
374 6ER9 FAD 3.51759
375 5Y77 FAD 3.51759
376 3SQP FAD 3.51759
377 4AT0 FAD 3.51759
378 2QA1 FAD 3.51759
379 4MIG G3F 3.51759
380 2ZXI FAD 3.51759
381 5M67 ADE 3.51759
382 5M67 3D1 3.51759
383 5MLR NAP 3.51759
384 5MLR GRQ 3.51759
385 5M67 NAD 3.51759
386 1FUR MLT 3.51759
387 4ZRN UPG 3.52564
388 4ZRN NAD 3.52564
389 5DF1 NAP 3.53261
390 5DF1 58X 3.53261
391 1XHC FAD 3.54223
392 2WSB NAD 3.54331
393 4DA6 GA2 3.55731
394 3LCV SAM 3.55872
395 4M73 M72 3.56083
396 4M73 SAH 3.56083
397 3P9C SAH 3.57143
398 4CNK FAD 3.58056
399 3KB6 NAD 3.59281
400 3G89 SAM 3.61446
401 6GAS FAD 3.62538
402 5ERG SAM 3.65535
403 6BWL NAD 3.65854
404 5Z75 NAD 3.66972
405 3DMH SAM 3.67454
406 3DMH GMP 3.67454
407 2BD0 NAP 3.68852
408 3FUU ADN 3.69004
409 3GD4 FAD 3.7182
410 3GD4 NAD 3.7182
411 2VT3 ATP 3.72093
412 6ARJ BW4 3.72493
413 6ARJ SAH 3.72493
414 5DX8 SFG 3.72493
415 5DX1 SFG 3.72493
416 5DXA SFG 3.72493
417 5DWQ SFG 3.72493
418 5DX0 SFG 3.72493
419 1T26 GBD 3.72671
420 1T26 NAI 3.72671
421 1XSE NDP 3.72881
422 3T7S SAM 3.73134
423 1F3L SAH 3.73832
424 2A92 NAI 3.73832
425 2IVD FAD 3.76569
426 3KLJ FAD 3.76884
427 5VN0 FAD 3.76884
428 2XVE FAD 3.76884
429 5MZI FYK 3.76884
430 5MZI FAD 3.76884
431 5VN0 NAI 3.76884
432 2R4J 13P 3.76884
433 2R4J FAD 3.76884
434 5OC1 FAD 3.76884
435 6F3M NAD 3.76884
436 1WDK NAD 3.77622
437 1O97 AMP 3.78788
438 1O97 FAD 3.78788
439 3C3Y SAH 3.79747
440 4MO2 FDA 3.80435
441 4MO2 FAD 3.80435
442 1JG3 ADN 3.82979
443 3GU3 SAH 3.87324
444 4NBW NAD 3.89105
445 5FFF NAP 3.89105
446 5FFF 5XC 3.89105
447 4CE5 PDG 3.9039
448 3U4C NDP 3.91459
449 6EL3 NAP 3.93701
450 5K0A FAD 3.93939
451 4A6D SAM 3.96601
452 4YJK URA 3.96825
453 2Q1S NAI 3.97878
454 2NPX FAD 4.0201
455 2NPX NAD 4.0201
456 3LXD FAD 4.0201
457 1V59 FAD 4.0201
458 5MBX FAD 4.0201
459 5MBX SP5 4.0201
460 2IID PHE 4.0201
461 2IID FAD 4.0201
462 5BVA FAD 4.0201
463 4D7E FAD 4.0201
464 1V59 NAD 4.0201
465 4DSG FAD 4.0201
466 4DSG UDP 4.0201
467 3EYA FAD 4.0201
468 3S1S SAH 4.0201
469 2V3V MGD 4.0201
470 4URF NAD 4.03226
471 3TKA SAM 4.03458
472 1IY8 NAD 4.11985
473 1VL8 NAP 4.11985
474 1H5Q NAP 4.15094
475 4GLL NAD 4.1543
476 1U2Z SAH 4.15704
477 4FZV SAM 4.17827
478 2Q0L FAD 4.18006
479 1RYI GOA 4.18848
480 1RYI FAD 4.18848
481 3C6K SPD 4.19948
482 3C6K MTA 4.19948
483 1J49 NAD 4.2042
484 4J4H 1J1 4.2471
485 4JK3 NAD 4.2471
486 1SB8 UD2 4.26136
487 1SB8 NAD 4.26136
488 5J5Z FAD 4.27136
489 5KOX FAD 4.27136
490 5KOX RFP 4.27136
491 4JDR FAD 4.27136
492 2RGO FAD 4.27136
493 3WGT FAD 4.32277
494 3WGT QSC 4.32277
495 4FN4 NAD 4.33071
496 1S7G APR 4.34783
497 1S7G NAD 4.34783
498 5J60 FAD 4.375
499 3ML1 MGD 4.44444
500 1YC5 NCA 4.47154
501 4BUZ OCZ 4.47154
502 4BUZ OAD 4.47154
503 4BUZ NAD 4.47154
504 3U31 NAD 4.48276
505 5DM1 SAH 4.49438
506 5DM1 5D7 4.49438
507 4UUG PXG 4.51807
508 5EEH SAH 4.52128
509 5EEH P9P 4.52128
510 1UWK URO 4.52261
511 1UWK NAD 4.52261
512 1D4D FAD 4.52261
513 3NTA FAD 4.52261
514 3NT6 FAD 4.52261
515 3NTD FAD 4.52261
516 6FHO FAD 4.52261
517 3LAD FAD 4.52261
518 2DTX BMA 4.54545
519 3CH6 NAP 4.54545
520 3CH6 311 4.54545
521 2A14 SAH 4.56274
522 5E1M SAH 4.56432
523 5E1M PRO PRO LYS ARG ILE ALA 4.56432
524 3LST SAH 4.5977
525 3ZV6 NAD 4.62633
526 3ZV6 4HB 4.62633
527 2PWY SAH 4.65116
528 5I39 FAD 4.65686
529 5N6C NAD 4.66667
530 2V6G NAP 4.67033
531 1H0H MGD 4.6729
532 5KVA SAM 4.67626
533 3QJ4 FAD 4.67836
534 3MB5 SAM 4.70588
535 4YRY FAD 4.71014
536 4YRY NAD 4.71014
537 1DL5 SAH 4.73186
538 3FRH SAH 4.74308
539 1KYQ NAD 4.74453
540 5FUB SAH 4.74777
541 4ZCC NAI 4.7619
542 4ZCC FAD 4.7619
543 6B92 SAH 4.7619
544 1ZGA SAH 4.7619
545 2EJU SAH 4.77387
546 5BRT FAD 4.77387
547 5BRT CH9 4.77387
548 6D6Y SAH 4.77387
549 5MIT FAD 4.77387
550 5MIT NAP 4.77387
551 1GTE FAD 4.77387
552 1PS9 FAD 4.77387
553 1SC6 NAD 4.77387
554 1GY8 NAD 4.78589
555 5OCM NAP 4.811
556 5EJ2 NAD 4.87013
557 1I8T FAD 4.90463
558 2XYQ SAH 4.91803
559 2Q7V FAD 4.92308
560 5NMX FAD 4.94118
561 5NMX NAP 4.94118
562 2VTD LKM 4.94382
563 4TQG NDP 4.95356
564 1G60 SAM 5
565 4IQY AR6 5
566 1NW5 SAM 5.01567
567 3BXO SAM 5.02092
568 5MPT SAH 5.02513
569 3QVP FAD 5.02513
570 2Y6Q FAD 5.02513
571 2Y6Q I7T 5.02513
572 3GDN FAD 5.02513
573 3GDN HBX 5.02513
574 2E7Z MGD 5.02513
575 4UCI SAM 5.02513
576 5UFN SAH 5.04202
577 2B4Q NAP 5.07246
578 5FTW SAH 5.07812
579 4PLT NAI 5.13595
580 4PLT OXM 5.13595
581 3RNM FAD 5.17241
582 4BLW AMP 5.19031
583 4BLW SAH 5.19031
584 5BSZ SAH 5.2
585 3MAG SAH 5.21173
586 1M2K APR 5.22088
587 4PIO SAH 5.26316
588 4PIO AVI 5.26316
589 2DKH 3HB 5.27638
590 2DKH FAD 5.27638
591 1MO9 FAD 5.27638
592 4XQC NAD 5.27638
593 1MO9 KPC 5.27638
594 4XQC 13D 5.27638
595 5FJN FAD 5.27638
596 5FJN BE2 5.27638
597 3M6W SAM 5.27638
598 1DMR PGD 5.27638
599 1U8X NAD 5.27638
600 5JE8 NAD 5.29801
601 1I1N SAH 5.30973
602 1WY7 SAH 5.31401
603 4CQM NAP 5.36398
604 5OJL TXP 5.36913
605 5GM1 SAH 5.38721
606 3MCT SAH 5.38721
607 4X60 SFG 5.42857
608 4X60 3XV 5.42857
609 1D4O NAP 5.43478
610 5W7M SAH 5.44872
611 3AXB PRO 5.52764
612 3AXB FAD 5.52764
613 2RAB NAD 5.52764
614 2RAB FAD 5.52764
615 2ZWA SAH 5.52764
616 2IVF MGD 5.52764
617 2FAV APR 5.55556
618 2O07 SPD 5.59211
619 2O07 MTA 5.59211
620 4KIB SAH 5.60224
621 3CTY FAD 5.64263
622 4GKV NAD 5.65476
623 4IWN GEK 5.67686
624 2G5C NAD 5.69395
625 5FA5 MTA 5.72207
626 1PR9 NAP 5.7377
627 3D3W NAP 5.7377
628 3EVF SAH 5.77617
629 3EVF GTA 5.77617
630 1VMK GUN 5.77617
631 5K7U SAM 5.77778
632 4HSU FAD 5.77889
633 4GUT FAD 5.77889
634 4FWE FAD 5.77889
635 4GUS FAD 5.77889
636 1GET FAD 5.77889
637 1GET NAP 5.77889
638 5TUK FAD 5.77889
639 3LU1 NAD 5.77889
640 3OID NDP 5.81395
641 3MQ2 SAH 5.9633
642 3FZG SAM 6
643 5LOG SAH 6.00858
644 3UCL NAP 6.03015
645 3UCL CYH 6.03015
646 3UCL FAD 6.03015
647 4REP FAD 6.03015
648 1PZG A3D 6.0423
649 2ZFU SAH 6.04651
650 2ZIF SAM 6.06061
651 1NVM NAD 6.08696
652 5X20 NAD 6.08974
653 1KEW NAD 6.09418
654 2VDV SAM 6.09756
655 1EJ0 SAM 6.11111
656 5IL1 SAM 6.13208
657 4OM8 NAD 6.14887
658 2DT5 NAD 6.16114
659 4X7Y SAH 6.20438
660 3P2E SAH 6.22222
661 2PT9 2MH 6.23053
662 2PT9 S4M 6.23053
663 5WUW NAP 6.27178
664 3CGD FAD 6.28141
665 3CGB FAD 6.28141
666 3CGD COA 6.28141
667 3CGD NAD 6.28141
668 5HSA FAS 6.28141
669 6H3O FAD 6.28141
670 2NVK FAD 6.28141
671 1PJS NAD 6.28141
672 4E13 NAD 6.36042
673 3QPB URA 6.38298
674 1LSS NAD 6.42857
675 5T2U NAP 6.45161
676 2QQF A1R 6.49351
677 2OD9 A1R NCA 6.49351
678 4POO SAM 6.5
679 5TUF TDC 6.53266
680 5TUF FAD 6.53266
681 1DJN ADP 6.53266
682 1O94 ADP 6.53266
683 6F5Z SAH 6.55738
684 4OBW SAM 6.61479
685 3LZW NAP 6.62651
686 3LZW FAD 6.62651
687 4QTU SAM 6.66667
688 1SOW NAD 6.70732
689 5YEC ATP 6.72269
690 1SZD APR 6.73401
691 1DJL NAP 6.76329
692 1G8K MGD 6.76692
693 4C4A SAH 6.78392
694 4KRG SAH 6.78392
695 5JCA FAD 6.78392
696 5JCA NDP 6.78392
697 2YG3 FAD 6.78392
698 4TQK NAG 6.78392
699 4NEC SAH 6.81818
700 2BGM NAJ 6.83453
701 4XUC SAM 6.88073
702 4XUC 43G 6.88073
703 3GEG NAD 6.88259
704 5JE0 SAH 6.88259
705 5JE0 AZ8 6.88259
706 3H2B SAH 6.89655
707 3QFA FAD 6.89655
708 5JGL SAM 6.92042
709 6ECU SAH 6.96203
710 4R6W PC 6.97674
711 4R6W SAH 6.97674
712 6ECW SAH 6.98413
713 4OPC FDA 7.03518
714 4OPC PGT 7.03518
715 3GMB FAD 7.03518
716 1Z3C SA8 7.04698
717 2I7C AAT 7.06714
718 1UDB NAD 7.10059
719 1UDB UFG 7.10059
720 1FP2 SAH 7.10227
721 1FP2 HMO 7.10227
722 5N53 8NB 7.17949
723 4USR FAD 7.20222
724 2FK8 SAM 7.2327
725 4RVG TYD 7.277
726 4RVG SAM 7.277
727 1Y8Q ATP 7.28643
728 3A4T SFG 7.29927
729 2YVJ FAD 7.33945
730 1QAN SAH 7.37705
731 5HXI FAD 7.38786
732 5HXI 5HN 7.38786
733 1U1I NAD 7.39796
734 5DLY SAH 7.5188
735 5DLY 5D7 7.5188
736 1ELI PYC 7.53769
737 2P41 SAH 7.54098
738 5ODQ FAD 7.6087
739 2OBF SAH 7.61246
740 2OBF F83 7.61246
741 4NTD FAD 7.64706
742 1XCL SAH 7.65957
743 3BGD SAH 7.69231
744 3BGD PM6 7.69231
745 1AE1 NAP 7.69231
746 3DXY SAM 7.79817
747 5M58 SAH 7.82609
748 5X68 FAD 7.92839
749 2RH4 EMO 7.94224
750 5E9W SAH 8.01282
751 3NJ4 AFX 8.0402
752 3NJ4 NAD 8.0402
753 4LWP SAH 8.15217
754 5Z2L NDP 8.16327
755 1QO8 FAD 8.29146
756 4YNU FAD 8.29146
757 4YNU LGC 8.29146
758 1FL2 FAD 8.3871
759 5N5D SAM 8.40708
760 3DUW SAH 8.52018
761 1E5Q NDP 8.54271
762 2BZG SAH 8.62069
763 3VC1 SAH 8.65385
764 3VC1 GST 8.65385
765 1ZEM NAD 8.77863
766 5THQ NDP 8.82353
767 1Q0S SAH 8.88031
768 2PX8 SAH 8.92193
769 2AG5 NAD 8.94309
770 3TN7 NJP 8.94942
771 1EFV FAD 9.01961
772 1EFV AMP 9.01961
773 1BDB NAD 9.02527
774 1P1C SAH 9.04523
775 5UR0 NAD 9.16905
776 2WK1 SAH 9.21986
777 5E72 SAM 9.24856
778 6CI9 NAP 9.26641
779 1XKQ NDP 9.28571
780 3Q9T FAY 9.29648
781 1GUZ NAD 9.35484
782 2EWM NAD 9.63855
783 2A8X FAD 9.799
784 1OBB NAD 9.799
785 3HDY FDA 9.82368
786 3HDY GDU 9.82368
787 3HDY FAD 9.82368
788 4Z0H NAD 9.88024
789 6BQ6 TER 9.96979
790 4M52 FAD 10.0503
791 4M52 M52 10.0503
792 1G55 SAH 10.2041
793 3V1Y NAD 10.3858
794 5UAO FAD 10.5528
795 2DPM SAM 10.5634
796 1JNR FAD 10.6667
797 4M37 SAH 10.7872
798 3NUG NAD 10.9312
799 1E6E FAD 10.9375
800 2HMT NAI 11.1111
801 3SJU NDP 11.1111
802 6EQS BV8 11.2727
803 3RIY NAD 11.3553
804 3LKZ SFG 11.809
805 2WA2 SAM 11.9565
806 1OAA OAA 11.9691
807 3H8V ATP 11.9863
808 2CDU FAD 12.0603
809 2CDU ADP 12.0603
810 2JAH NDP 12.1457
811 2JAP NDP 12.1457
812 2NXE SAM 12.2047
813 4PLG NAI 12.2754
814 4PLG OXM 12.2754
815 5GWX SAR 12.3239
816 5GWX SAM 12.3239
817 5L95 AMP 12.5448
818 1EDO NAP 12.7049
819 4NBU NAI 13.2
820 4YMH SAH 13.3333
821 5ZZ6 NAD 13.4615
822 5ZZ6 ADP 13.4615
823 4GQB 0XU 13.6364
824 1GEG NAD 13.6719
825 4M38 SAH 14.2857
826 2JJQ SAH 14.3216
827 1Q9I TEO 14.3216
828 1Q9I FAD 14.3216
829 5BUK FAD 14.3216
830 4YUW S4M 14.4737
831 4YUW 4JU 14.4737
832 2F5Z FAD 15.625
833 3NYC FAD 15.748
834 3NYC IAR 15.748
835 3AD8 NAD 16.1616
836 3AD8 PYC 16.1616
837 3AD8 FAD 16.1616
838 3HVJ 705 17.1946
839 2GDZ NAD 17.2285
840 4J56 FAD 17.5439
841 4II2 ATP 18.0723
842 3O03 NAP 18.2131
843 6DUB SAH 18.9189
844 3GCZ SAM 19.5035
845 5HJM MTA 20.7386
846 2GAG NAD 21.2121
847 2GAG FOA 21.2121
848 2GAG FAD 21.2121
849 1SQF SAM 21.608
850 5E8J SAH 27.2727
Pocket No.: 2; Query (leader) PDB : 3VSE; Ligand: SAH; Similar sites found with APoc: 52
This union binding pocket(no: 2) in the query (biounit: 3vse.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5Y8L HUI 1.69492
2 5TOW ADN 1.75879
3 5TOW NAI 1.75879
4 2IXB NAD 2.26131
5 2IXB A2G 2.26131
6 1W6U NAP 2.31788
7 9LDB NAD 2.40964
8 9LDT NAD 2.40964
9 2A0W DIH 2.42215
10 1WVG APR 2.50696
11 5DY5 5GR 2.63158
12 6CEP NAD 2.69461
13 4ZVV NAD 2.71084
14 4ZVV GN0 2.71084
15 3RJ5 NAD 2.75591
16 5M90 JIF 2.76382
17 3FWN ATR 2.76382
18 1ORR NAD 2.88184
19 2A8Y MTA 2.96296
20 4XYM COA 3.04348
21 4ZGS NAD 3.10881
22 2BFR ADP 3.125
23 4MCC 21X 3.25203
24 4G5H NAP 3.30579
25 4G5H UD7 3.30579
26 4RF2 NAP 3.30882
27 3B1F NAD 3.44828
28 4KXQ APR 3.55872
29 1HYH NAD 3.55987
30 1H9A NAP 4.0201
31 1WP4 NDP 4.15225
32 2CVZ NDP 4.15225
33 4J4H NAI 4.2471
34 3V1U NAD 5.52764
35 1JE1 GMP 5.9322
36 1TMO 2MD 6.03015
37 3VPH OXM 6.12903
38 3VPH NAD 6.12903
39 3APT FAD 6.12903
40 5T85 44G 6.13497
41 2HJR APR 6.40244
42 1A5Z NAD 6.58307
43 3NRR NAP 7.03518
44 3QV1 NAD 7.31707
45 4J1Q NDP 7.53769
46 1NFQ NAI 7.69231
47 2BOS GLA GAL GLC 10.2941
48 6HOY TSN 11.2583
49 6HOY AR6 11.2583
50 3ZG6 APR 11.4865
51 3EWP APR 12.9944
52 6AA8 NAD 21.5232
Pocket No.: 3; Query (leader) PDB : 3VSE; Ligand: SAH; Similar sites found with APoc: 10
This union binding pocket(no: 3) in the query (biounit: 3vse.bio4) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 4LHD GLY 3.01508
2 4XZ3 COA 3.04348
3 1IYE PGU 3.23625
4 5UAV NDP 3.72671
5 3SJ7 NDP 4.36508
6 3HB5 NAP 4.89297
7 1KQF MGD 8.29493
8 2VPY MGD 8.69565
9 3KVY URA 15.5779
10 1Y3A GDP 43.75
Pocket No.: 4; Query (leader) PDB : 3VSE; Ligand: SAH; Similar sites found with APoc: 10
This union binding pocket(no: 4) in the query (biounit: 3vse.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1JGT APC 2.01005
2 1GEE NAD 3.06513
3 2ZAT NAP 3.46154
4 3RKR NAP 3.81679
5 3A4V PYR 4.10095
6 3A4V NAD 4.10095
7 2RGH FAD 4.27136
8 1PVN MZP 6.11702
9 1ZOS MTM 6.52174
10 2BOS GLA GAL GLC NBU 10.2941
APoc FAQ
Feedback