Receptor
PDB id Resolution Class Description Source Keywords
3V51 1.95 Å EC: 2.7.11.17 CALCIUM-DEPENDENT PROTEIN KINASE 1 FROM TOXOPLASMA GONDII (T COMPLEX WITH INHIBITOR RM-1-176 TOXOPLASMA GONDII SERINE/THREONINE PROTEIN KINASE CALCIUM-BINDING ATP-BINDINKINASE INHIBITOR TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Ref.: MULTIPLE DETERMINANTS FOR SELECTIVE INHIBITION OF APICOMPLEXAN CALCIUM-DEPENDENT PROTEIN KINASE CDPK1 J.MED.CHEM. V. 55 2803 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
I76 A:701;
Valid;
none;
submit data
443.928 C25 H22 Cl N5 O CC(C)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3SXF 2.04 Å EC: 2.7.11.17 CALCIUM-DEPENDENT PROTEIN KINASE 1 FROM TOXOPLASMA GONDII (T COMPLEX WITH BUMPED KINASE INHIBITOR, RM-1-89 TOXOPLASMA GONDII SERINE/THREONINE PROTEIN KINASE TRANSFERASE CALCIUM-BINDINBINDING CALMODULIN EF HAND BUMPED KINASE INHIBITOR TRANTRANSFERASE INHIBITOR COMPLEX
Ref.: MULTIPLE DETERMINANTS FOR SELECTIVE INHIBITION OF APICOMPLEXAN CALCIUM-DEPENDENT PROTEIN KINASE CDPK1 J.MED.CHEM. V. 55 2803 2012
Members (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 4ONA ic50 = 0.002 uM UW1 C19 H23 N5 O2 CCOc1ccc2c....
2 4JBV ic50 = 0.003 uM V68 C26 H32 N6 O CC(C)COc1c....
3 3NYV - DTQ C16 H15 N3 O3 COc1cc2c(c....
4 3T3U Ki = 0.0025 uM BK6 C22 H24 N6 O COc1ccc2cc....
5 3KU2 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
6 4M84 ic50 = 0.049 uM 21E C17 H19 N5 O CC(C)(C)n1....
7 3HX4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
8 3UPX Ki = 0.0075 uM B6A C20 H22 N4 O c1ccc(cc1)....
9 3SXF Ki = 0.0025 uM BK5 C20 H21 N5 O CCOc1ccc2c....
10 3T3V Ki = 0.003 uM BK4 C19 H19 N5 O CC(C)n1c2c....
11 3I7B ic50 = 0.066 uM BK1 C19 H19 N5 CC(C)n1c2c....
12 3V5P Ki = 0.011 uM C88 C19 H24 N6 O Cc1cc(ccc1....
13 3V51 - I76 C25 H22 Cl N5 O CC(C)n1c2c....
14 3UPZ - B5A C11 H16 N6 c1c2c(ncnc....
15 3I7C ic50 = 0.018 uM BK2 C19 H19 N5 CC(C)(C)n1....
16 3V5T - UW9 C24 H30 N6 O CCOc1ccc2c....
17 3N51 - BK3 C22 H24 N6 c1ccc2c(c1....
70% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3IGO - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 3NCG - BK1 C19 H19 N5 CC(C)n1c2c....
3 3MWU - BK3 C22 H24 N6 c1ccc2c(c1....
4 4ONA ic50 = 0.002 uM UW1 C19 H23 N5 O2 CCOc1ccc2c....
5 4JBV ic50 = 0.003 uM V68 C26 H32 N6 O CC(C)COc1c....
6 3NYV - DTQ C16 H15 N3 O3 COc1cc2c(c....
7 3T3U Ki = 0.0025 uM BK6 C22 H24 N6 O COc1ccc2cc....
8 3KU2 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
9 4M84 ic50 = 0.049 uM 21E C17 H19 N5 O CC(C)(C)n1....
10 3HX4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
11 3UPX Ki = 0.0075 uM B6A C20 H22 N4 O c1ccc(cc1)....
12 3SXF Ki = 0.0025 uM BK5 C20 H21 N5 O CCOc1ccc2c....
13 3T3V Ki = 0.003 uM BK4 C19 H19 N5 O CC(C)n1c2c....
14 3I7B ic50 = 0.066 uM BK1 C19 H19 N5 CC(C)n1c2c....
15 3V5P Ki = 0.011 uM C88 C19 H24 N6 O Cc1cc(ccc1....
16 3V51 - I76 C25 H22 Cl N5 O CC(C)n1c2c....
17 3UPZ - B5A C11 H16 N6 c1c2c(ncnc....
18 3I7C ic50 = 0.018 uM BK2 C19 H19 N5 CC(C)(C)n1....
19 3V5T - UW9 C24 H30 N6 O CCOc1ccc2c....
20 3N51 - BK3 C22 H24 N6 c1ccc2c(c1....
21 3HZT - J60 C22 H27 Cl N4 O2 CCN(CC)CCN....
50% Homology Family (21)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3IGO - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 3NCG - BK1 C19 H19 N5 CC(C)n1c2c....
3 3MWU - BK3 C22 H24 N6 c1ccc2c(c1....
4 4ONA ic50 = 0.002 uM UW1 C19 H23 N5 O2 CCOc1ccc2c....
5 4JBV ic50 = 0.003 uM V68 C26 H32 N6 O CC(C)COc1c....
6 3NYV - DTQ C16 H15 N3 O3 COc1cc2c(c....
7 3T3U Ki = 0.0025 uM BK6 C22 H24 N6 O COc1ccc2cc....
8 3KU2 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
9 4M84 ic50 = 0.049 uM 21E C17 H19 N5 O CC(C)(C)n1....
10 3HX4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
11 3UPX Ki = 0.0075 uM B6A C20 H22 N4 O c1ccc(cc1)....
12 3SXF Ki = 0.0025 uM BK5 C20 H21 N5 O CCOc1ccc2c....
13 3T3V Ki = 0.003 uM BK4 C19 H19 N5 O CC(C)n1c2c....
14 3I7B ic50 = 0.066 uM BK1 C19 H19 N5 CC(C)n1c2c....
15 3V5P Ki = 0.011 uM C88 C19 H24 N6 O Cc1cc(ccc1....
16 3V51 - I76 C25 H22 Cl N5 O CC(C)n1c2c....
17 3UPZ - B5A C11 H16 N6 c1c2c(ncnc....
18 3I7C ic50 = 0.018 uM BK2 C19 H19 N5 CC(C)(C)n1....
19 3V5T - UW9 C24 H30 N6 O CCOc1ccc2c....
20 3N51 - BK3 C22 H24 N6 c1ccc2c(c1....
21 3HZT - J60 C22 H27 Cl N4 O2 CCN(CC)CCN....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: I76; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 I76 1 1
2 BK5 0.705882 0.907407
3 BK4 0.632184 0.851852
4 UW9 0.495146 0.816667
5 KS5 0.44898 0.754717
6 ABJ 0.445652 0.818182
7 2H1 0.445455 0.857143
8 V68 0.438596 0.765625
9 BK6 0.414414 0.707692
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3SXF; Ligand: BK5; Similar sites found: 424
This union binding pocket(no: 1) in the query (biounit: 3sxf.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3NGU ADP 0.02129 0.41932 None
2 5JU6 BGC 0.03687 0.40523 1.23967
3 3A23 GAL 0.03409 0.411 1.44628
4 2Z49 AMG 0.03646 0.40882 1.62037
5 4UWH JXM 0.007855 0.42792 1.65289
6 4A59 AMP 0.006613 0.41729 1.65289
7 2GVJ DGB 0.008736 0.41186 1.65289
8 1VPD TLA 0.03117 0.41117 1.67224
9 1U6R IOM 0.02819 0.4077 1.84211
10 1U6R ADP 0.02067 0.40085 1.84211
11 4ANW O92 0.0007727 0.42569 1.8595
12 4U98 ACP 0.00195 0.45302 1.98238
13 2PUL ACP 0.00002918 0.53996 2.01511
14 2IO8 ADP 0.002761 0.42429 2.06612
15 5E58 CPZ 0.02412 0.41388 2.06612
16 1BW9 PPY 0.01142 0.41997 2.24719
17 1C1X HFA 0.008324 0.43064 2.25352
18 3UDZ ADP 0.00001229 0.42706 2.27273
19 1E4E ADP 0.0166 0.40224 2.33236
20 3K5I ADP 0.00648 0.41769 2.48139
21 3B6R ADP 0.005544 0.43138 2.62467
22 2C5S AMP 0.0367 0.40534 2.66344
23 5HCN DAO 0.0485 0.40262 2.68199
24 2CFM AMP 0.007018 0.43863 2.68595
25 2G30 ALA ALA PHE 0.000008472 0.5831 2.71318
26 5MW8 ATP 0.0000163 0.44064 2.76008
27 2VDF OCT 0.001373 0.42754 2.7668
28 3V4S ATP 0.004792 0.4203 2.84238
29 1PZM 5GP 0.01234 0.43033 2.8436
30 4ME6 ADP 0.01622 0.4279 2.84974
31 1EHI ADP 0.003009 0.43626 2.91777
32 3JQ3 ADP 0.006709 0.43963 3.00546
33 2IF8 ADP 0.000872 0.49661 3.0303
34 2OHV NHL 0.03375 0.40728 3.0303
35 3ESS 18N 0.03801 0.40781 3.04348
36 5EXA 5SO 0.04408 0.4011 3.04348
37 3KYG 5GP 5GP 0.01165 0.40933 3.0837
38 2GPT SKM 0.04186 0.40613 3.09917
39 3P7N FMN 0.004305 0.42915 3.10078
40 1I3U RR1 0.02006 0.40797 3.14961
41 3W0O ADP 0.004432 0.40199 3.15186
42 3W0O HY0 0.004432 0.40199 3.15186
43 1IA9 ANP 0.00004888 0.51804 3.21429
44 3F81 STT 0.01945 0.42863 3.27869
45 2PYW ADP 0.00001776 0.53251 3.33333
46 3THR C2F 0.005362 0.43207 3.41297
47 3ORQ ADP 0.00352 0.42959 3.44828
48 4W9N TCL 0.01985 0.42374 3.53982
49 4URG C2E 0.02114 0.42136 3.59281
50 4AXD ANP 0.0001937 0.42846 3.72807
51 2PR5 FMN 0.006978 0.41953 3.78788
52 1PK8 ATP 0.0004417 0.45431 3.79147
53 2Y6P CTP 0.0347 0.40295 3.84615
54 4CYI ATP 0.00005063 0.40997 3.88128
55 4CJN QNZ 0.01261 0.43447 3.92562
56 4MRP GSH 0.01903 0.4201 3.92562
57 4DFU QUE 0.01828 0.42567 4.03727
58 4OCT AKG 0.02412 0.41112 4.05405
59 3T2W BTN 0.03899 0.40033 4.09836
60 1I7L ATP 0.000459 0.45729 4.20712
61 2QHS OCA 0.01286 0.42515 4.21941
62 2WBV SIA 0.01517 0.4319 4.2328
63 4ZS4 ATP 0.00003152 0.52675 4.23453
64 2GC0 PAN 0.001203 0.45865 4.25532
65 3X01 AMP 0.0008769 0.49875 4.3257
66 4XMF HSM 0.0397 0.40806 4.34783
67 2Q8Z NUP 0.005647 0.41111 4.38596
68 3ZJX BOG 0.004797 0.45995 4.49827
69 2WKQ FMN 0.005563 0.42404 4.51807
70 3QH2 3NM 0.04207 0.40601 4.52489
71 4OAV ACP 0.000001053 0.60866 4.54545
72 1OBD ATP 0.01015 0.42634 4.57516
73 2XG5 EC2 0.001511 0.48086 4.58716
74 2XG5 EC5 0.001511 0.48086 4.58716
75 4RW3 TDA 0.04289 0.40236 4.63576
76 1ULE GLA GAL NAG 0.00415 0.4591 4.66667
77 3PDT ADP 0.00003414 0.54295 4.72727
78 2QHV OC9 0.01099 0.43297 4.7619
79 4AVB CMP 0.01321 0.42061 4.8048
80 2AQX ATP 0.01247 0.40198 4.84429
81 3OF1 CMP 0.02788 0.40787 4.87805
82 2E5A LAQ 0.003018 0.41111 4.89914
83 1W2D ADP 0.001984 0.46664 4.90566
84 3QSB 743 0.02079 0.41445 4.91803
85 2YW2 ATP 0.003376 0.4304 4.95283
86 4O1P ANP 0.0000003792 0.45985 4.95868
87 1XL8 OCB 0.01156 0.40343 4.95868
88 2YBP 2HG 0.02398 0.42037 4.98688
89 3OPT AKG 0.01056 0.44094 5.09383
90 1DZK PRZ 0.002444 0.45265 5.09554
91 1AUX AGS 0.000165 0.49889 5.14469
92 5F2T PLM 0.004568 0.43539 5.19481
93 5JCJ 6JM 0.02718 0.41634 5.20833
94 1FWV SGA MAG FUC 0.03605 0.41062 5.22388
95 4GK9 MAN BMA MAN MAN MAN 0.03022 0.40349 5.37634
96 3NNT DQA 0.03698 0.40152 5.43478
97 1CKN GTP 0.01532 0.42539 5.45455
98 1CKM GTP 0.02364 0.41547 5.45455
99 4R78 AMP 0.0003953 0.50847 5.50162
100 3KFF ZBT 0.04183 0.40614 5.55556
101 3KFF XBT 0.04183 0.40614 5.55556
102 2VQD AP2 0.0006906 0.4613 5.60345
103 2YKL NLD 0.003268 0.45091 5.66038
104 1I1E DM2 0.000356 0.51744 5.78512
105 5MRH Q9Z 0.001731 0.47497 5.78512
106 4CFS HQD 0.01132 0.42396 5.92335
107 1VJE MSE 0.01673 0.42831 6.0241
108 1INN MET 0.03864 0.40149 6.0241
109 1GPM AMP 0.00772 0.44653 6.19835
110 3TDV GDP 0.00005546 0.52097 6.20915
111 2CDO GAL AAL GAL AAL GAL AAL 0.000322 0.52701 6.25
112 3UDG TMP 0.009469 0.43786 6.31229
113 2IZ1 ATR 0.02654 0.41902 6.32911
114 1QKQ MAN 0.002676 0.4161 6.33803
115 2ZMF CMP 0.005853 0.42303 6.34921
116 5WSY 7UC 0.04527 0.40049 6.35838
117 5WL0 21G 0.0235 0.40132 6.40496
118 4R38 RBF 0.005071 0.42247 6.42857
119 5E89 TD2 0.001874 0.45385 6.47482
120 4OCV ANP 0.0008576 0.46119 6.59631
121 1GSA ADP 0.0002125 0.40815 6.64557
122 5M6N 7H9 0.01857 0.42859 6.77966
123 4MTI 2DX 0.02153 0.42183 6.95652
124 3QRC SCR 0.00571 0.41028 7.00637
125 4GYI ADP 0.00007286 0.53316 7.0529
126 3RGA LSB 0.01642 0.40881 7.06714
127 5TT6 ATP 0.01011 0.40599 7.1066
128 2Q1A 2KT 0.01521 0.43419 7.16724
129 3CF6 SP1 0.0169 0.40821 7.18563
130 3EXS 5RP 0.03815 0.40081 7.23982
131 3P9T TCL 0.01971 0.41563 7.30594
132 3TAY MN0 0.002334 0.42424 7.36196
133 3VPC ADP 0.0003613 0.46966 7.44681
134 3UU7 2OH 0.03593 0.41038 7.56972
135 5LIA 6XN 0.009489 0.40486 7.64463
136 1JGS SAL 0.02312 0.42803 7.97101
137 1LNM DTX 0.008089 0.41336 8.15217
138 3CBG FER 0.02084 0.41506 8.18966
139 3OYW TDG 0.002722 0.47013 8.20895
140 4OFG PCG 0.02313 0.40839 8.33333
141 2CBZ ATP 0.0225 0.42547 8.43882
142 4CS9 AMP 0.01035 0.41679 8.46561
143 3I0O ADP 0.0003288 0.50642 8.55457
144 4IEN GDP 0.0193 0.40225 8.58896
145 3OQJ 3CX 0.03456 0.40304 8.67769
146 1GT4 UNA 0.001509 0.45833 8.80503
147 4IX4 ADP 0.0001053 0.40718 8.85714
148 3T4L ZEA 0.0002474 0.49068 8.88889
149 4FE2 AIR 0.0145 0.42249 9.01961
150 4FE2 ADP 0.01298 0.42098 9.01961
151 5LXT ACP 0.008196 0.40707 9.09091
152 5GWE GWM 0.038 0.40454 9.1358
153 4EES FMN 0.008504 0.41239 9.56522
154 3Q60 ATP 0.00001617 0.41315 9.7035
155 3N1S 5GP 0.02491 0.40676 10.084
156 1C1L GAL BGC 0.01284 0.42966 10.219
157 2V0U FMN 0.007367 0.41845 10.274
158 5EFW FMN 0.007684 0.41762 10.3448
159 5DJU FMN 0.006827 0.41667 10.3448
160 1I7M CG 0.03905 0.40029 10.4478
161 4MOB ADP 0.001607 0.4851 10.5422
162 3VPB ADP 0.0002666 0.46342 10.7143
163 3OBT SLB 0.01966 0.43329 10.8295
164 3WG3 A2G GAL NAG FUC 0.0005463 0.50113 11.236
165 3KYF 5GP 5GP 0.02187 0.41331 11.2554
166 4TX6 38B 0.02596 0.40245 11.2903
167 3E7S AT2 0.02797 0.40595 11.6009
168 3H0L ADP 0.005313 0.44952 11.7021
169 4NAE 1GP 0.04037 0.40753 12
170 4OUC 5ID 0.000007098 0.4156 12.605
171 2E27 AB0 0.006473 0.4361 12.6984
172 4AZT LY2 0.003624 0.45329 13.0165
173 4LRJ ANP 0.000003611 0.58318 13.0178
174 1IIU RTL 0.008336 0.4097 13.7931
175 3VHE 42Q 0.000002934 0.52535 14.2061
176 4I94 ANP 0.00001089 0.42034 14.6667
177 4NOS ITU 0.03611 0.40572 14.7541
178 4O9S 2RY 0.002535 0.41977 15.3488
179 2TPI ILE VAL 0.01702 0.40482 15.5172
180 1BHX ASP PHE GLU GLU ILE 0.0009494 0.48296 16.6667
181 3IWD M2T 0.03472 0.41056 17.7419
182 1ZTH ADP 0.000003836 0.60491 18.2171
183 1ZP9 ATP 0.00001957 0.55471 18.2171
184 5I35 ANP 0.0000108 0.4198 18.8295
185 3RE4 TO1 0.0000551 0.54595 20.155
186 4Y93 746 0.000009496 0.45666 20.852
187 4FL3 ANP 0.00000002898 0.64957 21.9008
188 3PVW QRX 0.0000004743 0.57199 22.1074
189 5UKL SIX 0.000001469 0.49247 22.1074
190 1TQP ATP 0.00002476 0.51095 22.3404
191 4Q5H ANP 0.0001553 0.50011 22.4138
192 4XH0 ADP 0.000002101 0.64085 23.8213
193 4BTK DTQ 0.00003913 0.40831 24.0356
194 1OPK P16 0.00000931 0.50175 24.7934
195 5GZ9 ANP 0.000002244 0.46458 24.918
196 4JR7 GNP 0.0000002704 0.46573 25.1337
197 5C03 AGS 0.00003475 0.41248 25.4386
198 5DMZ ADP 0.0000001047 0.648 25.7534
199 4NFN 2KC 0.000002566 0.59024 26.2136
200 4Y0X ADP 0.00000449 0.42641 26.4
201 3VRY B43 0.000000001862 0.67769 26.4317
202 4WW7 AMP 0.0001969 0.40582 26.8199
203 4WOV 3SM 0.0004852 0.49217 27.4448
204 4CRL C1I 0.0002073 0.43812 27.5862
205 3C1X CKK 0.0007286 0.45627 27.6139
206 2H8H H8H 0.0000004861 0.45994 27.686
207 4WNK 453 0.0000008037 0.51141 27.8926
208 3N7S 3N7 0.01677 0.43329 28.125
209 4L9I 8PR 0.00000009927 0.47265 28.3058
210 3KP6 SAL 0.03369 0.42083 28.4768
211 5LXC 7AA 0.000000003025 0.50373 28.9216
212 4ASE AV9 0.000002429 0.4814 29.1785
213 1Q8Y ADE 0.0000004976 0.65984 29.4906
214 1Q8Y ADP 0.0000001285 0.62839 29.4906
215 1Y57 MPZ 0.0002415 0.47313 29.646
216 3H9R TAK 0.00001304 0.58581 29.697
217 3KRL KRL 0.00002353 0.52177 29.8507
218 3E8N VRA 0.00000002871 0.52179 30.2053
219 3E8N ATP 0.00000002871 0.52179 30.2053
220 5LPZ ADP 0.000002657 0.44072 30.4217
221 5U6C 7YS 0.0000534 0.41913 30.4762
222 4OH4 ANP 0.00003831 0.52846 30.6306
223 4E93 GUI 0.00002372 0.48249 30.7692
224 5LI1 ANP 0.0000000348 0.51247 30.791
225 5EOB 5QQ 0.0000001506 0.58238 31.0345
226 5LI9 ACP 0.0000001875 0.62843 31.1429
227 3KMW ATP 0.001271 0.46189 31.3653
228 3LXN MI1 0.0000001019 0.63289 31.4465
229 4UAL 3FV 0.0000003703 0.46538 31.9809
230 4BKJ STI 0.0002079 0.41237 32.0635
231 3V8S 0HD 0.00000007973 0.47283 32.1951
232 1UO5 PIH 0.0008148 0.49294 32.3529
233 4IJP 1EH 0.00001003 0.4361 32.4022
234 2RIO ADP 0.0000001308 0.6518 32.4885
235 3PP0 03Q 0.00000006413 0.60746 32.5444
236 5HES 032 0.00000001239 0.52791 32.5733
237 4YZC STU 0.000000776 0.53292 32.5926
238 4AG8 AXI 0.000003631 0.49882 32.5949
239 4U0I 0LI 0.00005581 0.44988 32.6984
240 4GJ3 0XP 0.000001648 0.5045 33.1126
241 2X2M X2M 0.00000004728 0.64024 33.121
242 3TTI KBI 0.0000002072 0.58092 33.1897
243 5HCY 60D 0.00000003276 0.59428 33.2326
244 4KBA 1QM 0.000000805 0.55727 33.2326
245 5W4W 9WG 0.000000114 0.54418 33.2326
246 4P5Z Q7M 0.000007593 0.49814 33.241
247 4CLI 5P8 0.00009462 0.46421 33.3333
248 3UIM ANP 0.00001358 0.54947 33.4356
249 5T8O 76Z 0.0000004011 0.60624 33.5244
250 2F2U M77 0.0000001494 0.67673 33.5821
251 3HMO STU 0.0000005512 0.62205 33.6257
252 3GNI ATP 0.00001291 0.53872 33.6761
253 4U44 3D9 0.000001929 0.44533 33.7349
254 4IDT T28 0.00000111 0.60758 33.9888
255 2Z6C FMN 0.01188 0.40893 34.1085
256 5LPB ADP 0.00000179 0.41852 34.1216
257 5HVJ ANP 0.0000002353 0.69669 34.2857
258 2XVD AS6 0.0000002055 0.52669 34.4371
259 4YLL 4E3 0.00000001024 0.53739 34.903
260 1VJY 460 0.00000008745 0.55426 34.9835
261 3ORK AGS 0.000002548 0.54735 35.0482
262 4E1Z 0MX 0.000003732 0.5512 35.0515
263 4WB7 ATP 0.00002661 0.46783 35.0617
264 4K33 ACP 0.0000001551 0.63219 35.0769
265 3LXK MI1 0.000001072 0.55227 35.1682
266 2PVF ACP 0.0000002429 0.639 35.3293
267 2PZI AXX 0.00008884 0.52887 35.3306
268 3KRR DQX 0.0000009779 0.56001 35.5932
269 5MJA 7O3 0.0000004262 0.44627 35.7377
270 2JLD AG1 0.000002506 0.51491 35.9524
271 5NKB 8ZT 0.00003048 0.44316 36.2745
272 4ITH RCM 0.0002057 0.4804 36.3946
273 5N87 N66 0.000001789 0.5179 36.4217
274 4EWH T77 0.0000001082 0.59223 36.7273
275 2R5T ANP 0.00000004614 0.6407 36.7292
276 4M69 ANP 0.000001395 0.46177 36.7491
277 5AWM ANP 0.000005615 0.59648 36.802
278 2A19 ANP 0.000001516 0.62545 36.9718
279 4EUU BX7 0.00002249 0.50356 36.9906
280 4H3P ANP 0.0000004944 0.46133 37.0166
281 4F9C 0SX 0.000001166 0.60655 37.1191
282 5FBN 5WF 0.00000003778 0.57707 37.2694
283 4H3Q ANP 0.000001033 0.57525 37.2928
284 1U5R ATP 0.000001279 0.60464 37.3563
285 4QTB 38Z 0.000003044 0.52933 37.3684
286 3RI1 3RH 0.000002366 0.54349 37.3802
287 5UR1 YY9 0.0000006659 0.54359 37.6206
288 5BVE 4VG 0.0000001412 0.59093 37.6731
289 4AT3 LTI 0.00009445 0.46686 37.7926
290 2OO8 RAJ 0.0001681 0.40291 37.8549
291 4JDI ANP 0.00000006062 0.64299 37.8613
292 2QLU ADE 0.000005543 0.63136 37.8981
293 5VCV 1N1 0.0000003283 0.59039 37.9421
294 5JFS 6K0 0.00001658 0.48855 37.987
295 5UIU 8CG 0.000003329 0.4892 38.0805
296 3EKK GS2 0.0000004291 0.52531 38.1107
297 2Y6O 1N1 0.000001919 0.56958 38.1443
298 3BU5 ATP 0.0000008269 0.45269 38.2353
299 2WU6 DKI 0.0000003544 0.59527 38.3202
300 4YMJ 4EJ 0.000002939 0.63384 38.4868
301 2OFV 242 0.00007606 0.4584 38.6282
302 4YZN 4K5 0.0000004236 0.48666 38.676
303 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.0000002926 0.57373 38.8889
304 2JDR L20 0.0000002926 0.57373 38.8889
305 5MY8 RXZ 0.000003084 0.46912 38.9034
306 3GC8 B45 0.000001566 0.57346 38.9189
307 5USZ SKE 0.000133 0.42789 39.1003
308 5M06 ADP 0.0000031 0.42292 39.1304
309 5CEO 50D 0.00000714 0.4294 39.3333
310 1OUK 084 0.000001684 0.57642 39.3443
311 3SRV S19 0.0000006528 0.45346 39.3502
312 1U59 STU 0.000001188 0.59881 39.3728
313 3TXO 07U 0.00000006243 0.46846 39.3768
314 4RFM 3P6 0.000001205 0.46318 39.4737
315 4BHN BH9 0.000001222 0.46044 39.521
316 4WHZ 3NL 0.0000007335 0.46847 39.7403
317 3MVH WFE 0.0000007819 0.50982 39.7661
318 5JKG 6LF 0.0000037 0.50965 39.8714
319 4LOO SB4 0.0000002263 0.63238 39.8892
320 4F4P 0SB 0.000001527 0.54806 39.9267
321 4NM5 ADP 0.005413 0.40355 40.0531
322 1CM8 ANP 0.0001356 0.50819 40.0545
323 2PVN P63 0.000003393 0.52747 40.0568
324 2QCS ANP 0.0000005487 0.49969 40.2857
325 3SXS PP2 0.00000004252 0.64989 40.2985
326 1K3A ACP 0.0000007891 0.43858 40.4682
327 4D2S DYK 0.00000429 0.40641 40.493
328 2B9J ADP 0.000001338 0.60371 40.5099
329 2B9I ADP 0.000001865 0.58967 40.5099
330 2B9F ADP 0.000002504 0.5837 40.5099
331 2B9H ADP 0.000002126 0.45344 40.5099
332 3IDB ANP 0.000003166 0.55427 40.5714
333 1RE8 BD2 0.00001445 0.49747 40.5714
334 4WB6 ATP 0.0000006998 0.49656 40.5714
335 3FHI ANP 0.0000009182 0.49337 40.5714
336 5KO1 6UY 0.000006807 0.41926 40.636
337 2WQN ADP 0.000001329 0.61972 40.6452
338 3ZRM ZRM 0.00000452 0.57174 40.7008
339 5TA6 79D 0.000001268 0.54935 40.7821
340 5BYZ 4WE 0.000003027 0.49598 40.8046
341 5H2U 1N1 0.0000009239 0.45226 40.824
342 1XJD STU 0.0000001991 0.62724 40.8696
343 4Y8D 49J 0.0000004949 0.61654 40.8824
344 4IZY 1J2 0.000004284 0.56017 40.9214
345 4OTH DRN 0.000000003058 0.54198 41.0557
346 5DA3 58V 0.0000008587 0.63803 41.1321
347 4N70 2HX 0.00001257 0.50224 41.1585
348 5DH3 5BS 0.000006021 0.43737 41.2698
349 3ALN ANP 0.000002966 0.56732 41.2844
350 3NW7 LGV 0.000004471 0.51675 41.3681
351 1O9U ADZ 0.000002206 0.65811 41.4286
352 4UX9 ANP 0.0000002103 0.61879 41.4835
353 4NST ADP 0.00002679 0.4182 41.5954
354 4X7Q 3YR 0.00000128 0.59729 41.6667
355 3F7Z 34O 0.000001263 0.4491 41.7143
356 1BYG STU 0.0000004227 0.44779 41.7266
357 5TO8 7FM 0.00001546 0.48823 41.844
358 2CSN CKI 0.0000002067 0.58672 42.0875
359 3DLS ADP 0.000002609 0.42513 42.0896
360 2GU8 796 0.0000004481 0.5653 42.1365
361 3PTG 932 0.000003244 0.40861 42.1488
362 2F57 23D 0.000001168 0.6143 42.2713
363 3PLS ANP 0.0000001532 0.46719 42.2819
364 5EFQ ADP 0.00001631 0.4269 42.3631
365 5HX8 66P 0.00001247 0.51402 42.3841
366 3E7O 35F 0.000001687 0.50759 42.5
367 3G5D 1N1 0.0000009045 0.55346 42.6573
368 4WNP 3RJ 0.0000002397 0.65674 42.8571
369 3GQI ACP 0.000002174 0.58657 42.9448
370 5JGA 6KC 0.0000001935 0.5609 43.1746
371 3SLS ANP 0.0000003693 0.60102 43.4211
372 3SLS 77D 0.0001744 0.49777 43.4211
373 4XV1 904 0.0000004271 0.53433 43.4931
374 3PE2 E1B 0.0001772 0.45626 43.6202
375 5VC5 96M 0.0000006609 0.50343 43.9446
376 3OFM 4B0 0.000001077 0.43602 44
377 4L3L 5FI 0.000005967 0.48014 44.0789
378 4G31 0WH 0.000005886 0.50121 44.1472
379 5X8I SQZ 0.00000006394 0.48526 44.2197
380 2X4Z X4Z 0.00000001607 0.59057 44.2568
381 4TWP AXI 0.000001646 0.53178 44.2804
382 2Z7R STU 0.0000000813 0.6299 44.5483
383 3TKI S25 0.000006138 0.51892 44.582
384 2YAB AMP 0.0000002489 0.47697 44.5983
385 2HY0 306 0.000002591 0.60529 44.7205
386 4USF 6UI 0.00007716 0.42433 44.7368
387 4XLI 1N1 0.000001119 0.6074 44.7761
388 5IH9 6BF 0.000001596 0.51971 44.7761
389 5AX9 4KT 0.00001466 0.42001 44.8052
390 4QMN DB8 0.000005624 0.49973 44.8387
391 4NW6 2NS 0.00000009109 0.57318 44.8916
392 2J7T 274 0.00008456 0.46873 45.0331
393 2HK5 1BM 0.000000521 0.47324 45.1852
394 4BFM ANP 0.00000001356 0.67212 45.2096
395 5DEY 59T 0.000001936 0.53825 45.4545
396 3GC0 AMP 0.00000206 0.43141 45.5927
397 4CQE CQE 0.0000003562 0.60171 45.6835
398 5DRB 5FJ 0.000000001619 0.55393 45.7045
399 3CY2 MB9 0.000002137 0.56163 45.8599
400 3FHR P4O 0.00002436 0.53186 46.131
401 5LVP ATP 0.00000002693 0.46419 46.3022
402 5HQ0 LZ9 0.000001983 0.45667 46.6887
403 5UOX 8GY 0.000002887 0.45672 46.8635
404 4AUA 4AU 0.000009193 0.41821 46.9055
405 4CSV STI 0.00003286 0.42897 46.9091
406 4I6H 1C8 0.000008082 0.55997 47.0779
407 3GGF GVD 0.000001928 0.6037 47.5083
408 5DBX ANP 0.000001282 0.42549 47.561
409 2BPM 529 0.00003014 0.4224 47.5728
410 1ZY5 ANP 0.000009563 0.56303 47.8548
411 4KS7 X4Z 0.0000001422 0.61236 47.9452
412 4CFU 2WC 0.000007007 0.57642 48.5149
413 4BCQ TJF 0.00002454 0.56385 48.8372
414 4BCM T7Z 0.000001154 0.4452 48.8372
415 3DAK ANP 0.00000005652 0.6783 48.9655
416 4BCN T9N 0.00000991 0.57629 49
417 3C0G 3AM 0.0000002839 0.44563 49.2878
418 1UNH IXM 0.000001066 0.42769 49.3151
419 3O0G 3O0 0.000009365 0.41848 49.3151
420 2XMY CDK 0.000000008364 0.64303 49.3289
421 5LMK 6ZK 0.00001728 0.40202 49.4949
422 3M2W L8I 0.00000007256 0.68257 49.4983
423 4AU8 Z3R 0.00001562 0.57384 49.6622
424 4A4X JUP 0.00002609 0.44655 49.8208
425 3QCQ 3Q0 0.000001731 0.56641 50
426 2XK9 XK9 0.0000003572 0.54346 50
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