Receptor
PDB id Resolution Class Description Source Keywords
3UEC 2.18 Å NON-ENZYME: TOXIN_VIRAL CRYSTAL STRUCTURE OF HUMAN SURVIVIN BOUND TO HISTONE H3 PHOS ON THREONINE-3. HOMO SAPIENS ZINC FINGER PHOSPHORYLATED THREONINE CELL CYCLE BIR DOMAICHROMOSOMAL PASSENGER COMPLEX CELL DIVISION MITOSIS
Ref.: MOLECULAR BASIS FOR PHOSPHOSPECIFIC RECOGNITION OF H3 TAILS BY SURVIVIN PARALOGUES AT INNER CENTROMERE MOL.BIOL.CELL V. 23 1457 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
1PE A:146;
Invalid;
none;
submit data
238.278 C10 H22 O6 C(COC...
ACT A:148;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
ALA ARG TPO LYS B:1;
Valid;
none;
Kd = 60.6 uM n/a n/a n/a n/a
EDO A:144;
A:147;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
PEG A:149;
Invalid;
none;
submit data
106.12 C4 H10 O3 C(COC...
PG4 A:145;
Invalid;
none;
submit data
194.226 C8 H18 O5 C(COC...
ZN A:143;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3UEC 2.18 Å NON-ENZYME: TOXIN_VIRAL CRYSTAL STRUCTURE OF HUMAN SURVIVIN BOUND TO HISTONE H3 PHOS ON THREONINE-3. HOMO SAPIENS ZINC FINGER PHOSPHORYLATED THREONINE CELL CYCLE BIR DOMAICHROMOSOMAL PASSENGER COMPLEX CELL DIVISION MITOSIS
Ref.: MOLECULAR BASIS FOR PHOSPHOSPECIFIC RECOGNITION OF H3 TAILS BY SURVIVIN PARALOGUES AT INNER CENTROMERE MOL.BIOL.CELL V. 23 1457 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 62 families.
1 3UEC Kd = 60.6 uM ALA ARG TPO LYS n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 43 families.
1 3UEC Kd = 60.6 uM ALA ARG TPO LYS n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 35 families.
1 3UEC Kd = 60.6 uM ALA ARG TPO LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ALA ARG TPO LYS; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3UEC; Ligand: ALA ARG TPO LYS; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3uec.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback