Receptor
PDB id Resolution Class Description Source Keywords
3U3Y 2.28 Å EC: 3.1.11.2 MOUSE TREX1 D200H MUTANT MUS MUSCULUS RNASE H FOLD 3-prime EXONUCLEASE HOMODIMER HYDROLASE-DNA COMPL
Ref.: DEFECTS IN DNA DEGRADATION REVEALED IN CRYSTAL STRU TREX1 EXONUCLEASE MUTATIONS LINKED TO AUTOIMMUNE DI DNA REPAIR V. 11 65 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BU1 A:315;
Invalid;
none;
submit data
90.121 C4 H10 O2 C(CCO...
CA C:5;
D:5;
Part of Protein;
Part of Protein;
none;
none;
submit data
40.078 Ca [Ca+2...
DG DA DC DG C:1;
D:1;
Valid;
Valid;
none;
none;
submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3U3Y 2.28 Å EC: 3.1.11.2 MOUSE TREX1 D200H MUTANT MUS MUSCULUS RNASE H FOLD 3-prime EXONUCLEASE HOMODIMER HYDROLASE-DNA COMPL
Ref.: DEFECTS IN DNA DEGRADATION REVEALED IN CRYSTAL STRU TREX1 EXONUCLEASE MUTATIONS LINKED TO AUTOIMMUNE DI DNA REPAIR V. 11 65 2012
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3U3Y - DG DA DC DG n/a n/a
2 3U6F - DG DA DC DG n/a n/a
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3U3Y - DG DA DC DG n/a n/a
2 3U6F - DG DA DC DG n/a n/a
3 3B6O - TMP C10 H15 N2 O8 P CC1=CN(C(=....
4 2OA8 - DG DA DC DG n/a n/a
5 3B6P - TMP C10 H15 N2 O8 P CC1=CN(C(=....
6 2O4G - TMP C10 H15 N2 O8 P CC1=CN(C(=....
7 2IOC - D5M C10 H14 N5 O6 P c1nc(c2c(n....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3U3Y - DG DA DC DG n/a n/a
2 3U6F - DG DA DC DG n/a n/a
3 3B6O - TMP C10 H15 N2 O8 P CC1=CN(C(=....
4 2OA8 - DG DA DC DG n/a n/a
5 3B6P - TMP C10 H15 N2 O8 P CC1=CN(C(=....
6 2O4G - TMP C10 H15 N2 O8 P CC1=CN(C(=....
7 2IOC - D5M C10 H14 N5 O6 P c1nc(c2c(n....
8 6A46 - DCM C9 H14 N3 O7 P C1[C@@H]([....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: DG DA DC DG; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: DG DA DC DG; Similar ligands found: 1
No: Ligand Similarity coefficient
1 DG DA DC DG 1.0000
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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