Receptor
PDB id Resolution Class Description Source Keywords
3TXO 2.05 Å EC: 2.7.11.13 PKC ETA KINASE IN COMPLEX WITH A NAPHTHYRIDINE HOMO SAPIENS KINASE PHOSPHOTRANSFERASE TRANSFERASE-TRANSFERASE INHIBITO
Ref.: 2,6-NAPHTHYRIDINES AS POTENT AND SELECTIVE INHIBITO NOVEL PROTEIN KINASE C ISOZYMES. BIOORG.MED.CHEM.LETT. V. 21 7367 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
07U A:1;
Valid;
none;
ic50 = 9 nM
293.366 C17 H19 N5 CC(C)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3TXO 2.05 Å EC: 2.7.11.13 PKC ETA KINASE IN COMPLEX WITH A NAPHTHYRIDINE HOMO SAPIENS KINASE PHOSPHOTRANSFERASE TRANSFERASE-TRANSFERASE INHIBITO
Ref.: 2,6-NAPHTHYRIDINES AS POTENT AND SELECTIVE INHIBITO NOVEL PROTEIN KINASE C ISOZYMES. BIOORG.MED.CHEM.LETT. V. 21 7367 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3TXO ic50 = 9 nM 07U C17 H19 N5 CC(C)(CNc1....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3TXO ic50 = 9 nM 07U C17 H19 N5 CC(C)(CNc1....
50% Homology Family (492)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 2E9O ic50 = 20 nM A58 C25 H27 N3 O2 CC1CCC(CC1....
2 2WMQ - ZYQ C9 H11 N3 O2 S CC(=O)Nc1n....
3 2BRO ic50 = 1.4 uM DF2 C21 H20 N4 O2 c1ccc(cc1)....
4 2QHN ic50 = 980 nM 582 C13 H13 N3 O CCN1c2cccc....
5 4RVM ic50 = 1 nM 3X7 C23 H21 N5 c1cc(ccc1C....
6 5DLS ic50 = 4.4 nM 5CV C31 H34 N6 O3 CC(C)(CN(C....
7 3TKI ic50 = 0.05 nM S25 C20 H23 N7 O2 S c1cnc(cc1N....
8 2YM5 ic50 = 0.43 uM YM5 C18 H21 N5 O2 c1cc(cc(c1....
9 4HYH ic50 = 1 nM 1AM C22 H22 N6 O3 S COc1ccc2c(....
10 1NVS Ki = 15 nM UCM C24 H15 N3 O3 c1ccc2c(c1....
11 2YDK ic50 = 0.007 uM YDK C17 H20 N4 O2 S c1ccc(cc1)....
12 3OT3 ic50 = 0.005 uM 22K C16 H20 Br N7 Cn1cc(cn1)....
13 2HXQ ic50 = 144 nM 373 C24 H26 N4 O c1ccc2c(c1....
14 2QHM ic50 = 660 nM 7CS C16 H19 N3 O2 CN1[C@H]2C....
15 2BRH ic50 = 22 uM DFW C20 H15 N3 O3 c1ccc(cc1)....
16 2R0U ic50 = 1 nM M54 C25 H22 N4 O2 c1cc(cc(c1....
17 1NVR Ki = 7.8 nM STU C28 H26 N4 O3 C[C@@]12[C....
18 3OT8 ic50 = 0.009 uM MI5 C19 H22 N8 S Cc1cc(sn1)....
19 2YM4 ic50 = 1.5 uM 4YM C21 H22 N6 O3 CCOC(=O)c1....
20 4HYI ic50 = 2 nM 1AO C21 H20 N6 O S c1ccc2c(c1....
21 4RVL ic50 = 41.7 nM 3XL C17 H10 N4 O c1ccc(c(c1....
22 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
23 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
24 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
25 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
26 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
27 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
28 5F4N ic50 = 2.2 nM 5UY C17 H19 N7 O3 COC(=O)c1c....
29 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
30 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
31 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
32 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
33 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
34 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
35 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
36 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
37 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
38 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
39 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
40 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
41 3JVS Ki = 0.146 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
42 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
43 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
44 2C3L Ki = 0.026 uM IDZ C14 H10 N4 c1ccc2c(c1....
45 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
46 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
47 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
48 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
49 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
50 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
51 1JSV - U55 C10 H11 N5 O2 S c1cc(ccc1N....
52 1OIQ ic50 = 2.9 uM HDU C14 H13 N5 O Cc1c(n2ccc....
53 2W17 ic50 = 0.002 uM I19 C24 H30 F N7 O Cc1ncc(n1C....
54 2VTP ic50 = 0.003 uM LZ9 C17 H11 F3 N4 O2 c1cc(c(c(c....
55 1JVP ic50 = 1.6 uM LIG C15 H11 N3 c1ccc-2c(c....
56 1FVT - 106 C14 H9 Br N4 O3 S c1cc(ccc1/....
57 4KD1 - 1QK C21 H29 N6 O2 CCc1cnn2c1....
58 3LE6 ic50 = 0.035 uM 2BZ C17 H10 Cl N5 O2 Cc1c-2nc(c....
59 2VTI ic50 = 0.66 uM LZ3 C14 H12 N4 O3 S c1ccc2c(c1....
60 3LFS Ki = 2.5 uM A07 C17 H16 Cl N3 O CCCC(=O)Nc....
61 1PXI - CK1 C8 H5 Cl2 N3 S c1cnc(nc1c....
62 4LYN - 1YG C20 H23 N3 O2 S2 C[C@@H](c1....
63 1YKR ic50 = 0.56 uM 628 C20 H14 Cl2 N4 O3 S c1cc(c(c(c....
64 1PXN Ki ~ 0.32 uM CK6 C15 H15 N5 O S Cc1c(sc(n1....
65 2R3J ic50 = 10 nM SCJ C18 H14 Br N5 c1ccc(cc1)....
66 3IG7 ic50 = 9 nM EFP C18 H22 N4 O3 CC(=O)NC1C....
67 2VTS ic50 = 0.03 uM LZC C16 H23 N7 CC(C)Nc1cc....
68 1P2A ic50 = 12 nM 5BN C17 H15 F N4 O c1cc([nH]c....
69 2BHE ic50 = 1 uM BRY C16 H9 Br N2 O2 c1ccc2c(c1....
70 3UNK ic50 = 15 uM 0BY C17 H13 Cl N4 O2 c1ccc(c(c1....
71 2VTQ ic50 = 0.14 uM LZA C16 H17 F2 N5 O2 c1cc(c(c(c....
72 2C68 ic50 = 1.8 uM CT6 C18 H15 Br N5 c1cc(cc(c1....
73 3TIZ - 3TI C17 H13 N O2 c1ccc2c(c1....
74 3PXY ic50 = 5.9 uM JWS C10 H11 N5 O2 COc1ccc(c(....
75 2R3M ic50 = 10 nM SCX C19 H17 F2 N7 CCc1cnn2c1....
76 5JQ5 Kd = 2341 nM I74 C22 H30 N6 O CC(C)c1cnn....
77 2C6O - 4SP C18 H22 N6 O3 S c1cc(ccc1N....
78 1V1K Ki = 35 uM 3FP C22 H23 F4 N5 O2 CN(C)C[C@H....
79 2VTJ ic50 = 1.9 uM LZ4 C10 H9 Cl N4 O2 S c1cc(ccc1N....
80 3EZV - EZV C25 H25 N7 CN1CCN(CC1....
81 3PXZ Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
82 1W0X - OLO C15 H18 N6 O Cn1cnc2c1n....
83 2XMY Ki = 0.11 nM CDK C18 H21 N5 O4 S2 CC1=C(SC(=....
84 2UZO ic50 = 18 uM C62 C14 H10 N2 O5 S2 c1cc(ccc1c....
85 1KE7 ic50 = 8.9 nM LS3 C20 H15 N3 O4 S c1cc2c(cc1....
86 1DM2 - HMD C11 H10 Br N5 O2 C1CNC(=O)C....
87 1DI8 ic50 = 1 uM DTQ C16 H15 N3 O3 COc1cc2c(c....
88 5JQ8 - I73 C22 H30 N6 O CC(C)c1cnn....
89 1GIJ - 2PU C19 H22 N6 O2 c1cc2c(c(c....
90 2R3P ic50 = 900 nM 3SC C19 H12 Cl2 N6 S c1cc(c(c(c....
91 1KE8 ic50 = 1000 nM LS4 C18 H14 N4 O3 S2 c1ccc2c(c1....
92 2C6I ic50 = 11 uM DT1 C18 H22 N6 O3 S c1cc(ccc1N....
93 1PXP Ki ~ 0.22 uM CK8 C17 H19 N5 S Cc1c(sc(n1....
94 2UZN ic50 = 0.03 uM C96 C15 H13 N3 O4 S2 [H]/N=C/1N....
95 2B55 ic50 = 96 nM D31 C24 H31 N5 O2 c1cc-2c(c(....
96 5K4J - 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
97 3PJ8 - 404 C19 H26 N6 O CC[C@H](CO....
98 3LFQ - A28 C17 H15 F2 N3 O CCCC(=O)Nc....
99 2W05 ic50 = 0.001 uM FRT C20 H26 N6 O3 S Cc1ncc(n1C....
100 2XNB Ki = 149 nM Y8L C19 H22 N6 O S CC1=C(SC(=....
101 1HCK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
102 5IEX - 6AF C17 H21 Br N4 O3 S C[C@H]([C@....
103 2R3H ic50 = 20000 nM SCE C13 H13 N5 Cc1cnc2n1c....
104 3LFN Ki = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
105 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
106 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
107 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
108 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
109 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
110 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
111 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
112 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
113 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
114 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
115 2DS1 ic50 = 6.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
116 5FP5 - 1Y6 C7 H5 F O2 c1cc(ccc1C....
117 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
118 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
119 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
120 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
121 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
122 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
123 5IEV - R0N C18 H23 F3 N4 O3 S C[C@H]([C@....
124 4D1X - ESJ C11 H8 N2 O3 S2 c1cc2c(cc1....
125 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
126 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
127 5FP6 - MFZ C11 H7 Cl2 N O c1cc(c2c(c....
128 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
129 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
130 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
131 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
132 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
133 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
134 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
135 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
136 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
137 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
138 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
139 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
140 5A14 - LQ5 C24 H26 F3 N7 O2 CN1CCN(CC1....
141 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
142 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
143 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
144 5D1J ic50 = 48 nM 56H C17 H24 N4 O2 S2 CC(C)(C)c1....
145 5IEY - 6AE C14 H19 N5 O3 S C[C@H]([C@....
146 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
147 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
148 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
149 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
150 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
151 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
152 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
153 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
154 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
155 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
156 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
157 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
158 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
159 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
160 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
161 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
162 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
163 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
164 1H08 - BYP BWP n/a n/a
165 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
166 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
167 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
168 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
169 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
170 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
171 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
172 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
173 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
174 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
175 1PYE ic50 = 0.32 uM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
176 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
177 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
178 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
179 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
180 4D1Z - WG8 C13 H10 N2 O3 S c1cc2ccc(n....
181 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
182 5LI9 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
183 3A8W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
184 3MB6 ic50 = 100 nM 01I C16 H8 O6 c1cc2c(cc(....
185 5M4F - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
186 5CVH - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
187 3BQC ic50 ~ 2 uM EMO C15 H10 O5 Cc1cc2c(c(....
188 5CU2 - 54G C8 H8 O3 Cc1ccc(c(c....
189 5MO5 - 4IH C17 H21 Cl N2 O2 S CS(=O)(=O)....
190 5M4I - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
191 5MP8 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
192 5MOV - HC4 C9 H8 O3 c1cc(ccc1C....
193 5MOH - YTX C9 H10 O4 COc1cc(ccc....
194 5CSH Kd = 270 uM 54E C13 H12 Cl N c1ccc(cc1)....
195 3OWL ic50 = 0.67 uM 19E C16 H11 Cl N2 O Cc1cnc(c2c....
196 5H8G ic50 < 0.003 uM 5Y4 C23 H29 N9 O CC(=O)Nc1c....
197 5B0X ic50 = 0.02 uM HCK C18 H14 N2 O4 S COc1ccc(cc....
198 5MO8 Kd = 1.64 uM C98 C26 H26 Cl N3 O4 c1ccc(cc1)....
199 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
200 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
201 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
202 5H8E ic50 < 0.003 uM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
203 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
204 5MOE Kd = 500 uM OQC C11 H10 Cl N O c1cc(c(cc1....
205 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
206 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
207 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
208 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
209 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
210 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
211 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
212 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
213 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
214 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
215 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
216 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
217 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
218 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
219 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
220 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
221 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
222 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
223 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
224 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
225 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
226 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
227 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
228 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
229 3PE1 Ki = 0.38 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
230 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
231 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
232 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
233 2ZJW ic50 = 0.04 uM REF C14 H6 O8 c1c2c-3c(c....
234 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
235 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
236 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
237 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
238 3FHR - P4O C21 H16 N4 O c1ccc2c(c1....
239 3R1N - 05B C22 H21 N5 O3 c1cc2c(cc1....
240 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
241 3BWJ ic50 = 2.6 uM ARX C28 H47 N15 O7 [H]/N=C(N)....
242 3AGL Ki = 16 nM A03 C37 H63 N17 O9 [H]/N=C(N)....
243 1RE8 Ki = 0.3 nM BD2 C27 H26 N2 O6 c1ccc(c(c1....
244 1REJ Ki = 5 nM B1L C20 H22 N2 O5 c1cc(ccc1C....
245 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
246 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
247 5IZF Kd = 1.7 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
248 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
249 2Z7Q - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
250 2Z7R ic50 = 3 nM STU C28 H26 N4 O3 C[C@@]12[C....
251 4UZH ic50 = 9800 nM JVE C15 H13 F N4 O c1ccc(c(c1....
252 2C6E - HPM C28 H31 N7 O4 COc1cc2c(c....
253 3H0Y ic50 = 0.006 uM 48B C23 H17 Cl F N5 O2 c1ccc(c(c1....
254 4B0G ic50 = 0.015 uM VEK C19 H21 Br N8 O Cc1cc(no1)....
255 4JBP ic50 = 41 nM YPH C34 H36 N6 O4 c1ccc(cc1)....
256 3H10 - 97B C30 H25 Cl F2 N6 O CN1CCN(CC1....
257 1MQ4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
258 5EW9 Ki < 0.01 nM 5VC C22 H21 Cl F N3 O3 S c1cc(nc(c1....
259 4CEG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
260 3DJ6 - AK6 C25 H24 N4 O3 S COc1ccc(cc....
261 2WQE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
262 3FDN ic50 = 0.033 uM MMH C21 H22 N6 O3 Cc1c(c([nH....
263 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
264 5DR9 - 5E2 C16 H9 Br Cl N O2 c1cc(cc(c1....
265 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
266 5DN3 Kd = 3.77 uM 5DN C16 H9 Br F N O2 c1cc(cc(c1....
267 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
268 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
269 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
270 5DT0 - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
271 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
272 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
273 5DR2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
274 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
275 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
276 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
277 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
278 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
279 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
280 5DRD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
281 5DPV - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
282 4UYN ic50 = 2 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
283 5DT3 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
284 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
285 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
286 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
287 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
288 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
289 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
290 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
291 4KS7 - X4Z C25 H28 N8 O S Cc1nc2ccsc....
292 1M2P - HNA C14 H7 N O6 c1cc2c(c(c....
293 1LPU - BEN C7 H8 N2 [H]/N=C(c1....
294 2QC6 ic50 = 0.1 uM G12 C10 H6 Br2 O3 CC1=C(C(=O....
295 4ANM ic50 = 28 nM WUL C15 H14 Br N3 O3 c1cc2c(cc1....
296 1DAW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
297 4RLK - E91 C21 H14 N2 O2 c1ccc2c(c1....
298 2OXD - K32 C7 H2 Br4 N2 O c12c(c(c(c....
299 2PVM Ki = 0.36 uM P29 C17 H15 N9 c1ccc(cc1)....
300 1J91 - TBS C6 H Br4 N3 c12c(c(c(c....
301 4DGO ic50 = 0.57 uM 0JW C10 H10 N2 O3 c1cc(c(cc1....
302 3FL5 - TXQ C14 H8 O6 c1cc(c(c2c....
303 3PWD ic50 = 0.22 uM CZ0 C14 H9 N O5 CC1=CC(=O)....
304 3KXH - K66 C11 H9 Br4 N3 O2 CN(C)c1nc2....
305 4DGM ic50 = 1.2 uM AGI C15 H10 O5 c1cc(ccc1C....
306 3PVG - K68 C9 H4 Br4 N2 O2 c1nc2c(n1C....
307 1ZOG Ki = 0.07 uM K37 C8 H4 Br4 N2 S CSc1[nH]c2....
308 2PVJ Ki = 0.005 uM P44 C19 H21 N7 c1ccc(cc1)....
309 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
310 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
311 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
312 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
313 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
314 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
315 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
316 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
317 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
318 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
319 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
320 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
321 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
322 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
323 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
324 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
325 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
326 1JKL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
327 3F5G - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
328 5AUZ ic50 = 98 uM GEN C15 H10 O5 c1cc(ccc1C....
329 1P4F - DRG C12 H11 N3 c1ccc-2c(c....
330 4TXC Kd = 0.24 uM 38G C24 H27 N5 O3 CN(C)CCN[C....
331 2YAK ic50 = 2 nM OSV C27 H31 F N4 O3 Ru S4 CC(C)Oc1cc....
332 5AUY ic50 = 1.6 uM MRI C15 H10 O7 c1cc(c(cc1....
333 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
334 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
335 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
336 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
337 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
338 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
339 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
340 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
341 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
342 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
343 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
344 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
345 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
346 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
347 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
348 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
349 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
350 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
351 3QD4 ic50 = 0.00000001 M 3Q6 C22 H30 N8 O2 C[C@@H]1C[....
352 3RCJ ic50 = 0.8 uM 3RC C16 H13 N5 c1ccc(cc1)....
353 2PE0 - 39Z C14 H12 N2 O2 CC(c1ccc[n....
354 4CT2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
355 5ACK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
356 3HRC - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
357 5LVM - ADE C5 H5 N5 c1[nH]c2c(....
358 5MRD ic50 = 36.4 uM S26 C18 H13 Cl N2 O4 S2 CCOC(=O)C1....
359 3ION ic50 = 8 nM 8H1 C28 H27 N5 O3 COc1cc2c3c....
360 1UU7 ic50 = 14 uM BI2 C27 H26 N4 O2 C[N@@]1CCC....
361 3HRF Kd = 10.3 uM P47 C17 H15 Cl O2 c1ccc(cc1)....
362 3QCS ic50 = 0.00000001 M 3Q1 C15 H17 N7 O c1cc2c(cc1....
363 1H1W - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
364 4AW1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
365 2PE2 - 464 C28 H30 N6 O3 c1cc(cc(c1....
366 3H9O ic50 = 70 nM 9BD C19 H19 N5 O3 COCCOc1cc2....
367 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
368 5HKM ic50 = 0.013 uM 61Y C16 H15 N7 CCc1cc(nc(....
369 3QD0 ic50 = 0.00000001 M 3Q4 C24 H26 N8 O C[C@@H]1CC....
370 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
371 5LVN Kd = 20 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
372 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
373 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
374 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
375 3QCX ic50 = 0.00000001 M 3Q2 C16 H19 N7 O C[C@@H]1CO....
376 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
377 5LVL Kd = 1.25 uM 537 C14 H8 N2 O c1ccc2c(c1....
378 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
379 3QCY ic50 = 0.00000001 M 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
380 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
381 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
382 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
383 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
384 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
385 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
386 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
387 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
388 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
389 4QMP ic50 = 0.014 uM DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
390 4U8Z - 3FE C17 H15 N5 O c1cc(cc(c1....
391 4QMX ic50 = 11 uM H8H C27 H32 Cl N5 O5 CN1CCN(CC1....
392 4QMT ic50 = 0.01 uM H1N C29 H32 N4 O3 S CCS(=O)(=O....
393 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
394 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
395 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
396 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
397 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
398 4NUS ic50 = 0.005 uM 2NK C22 H21 F2 N3 O CN1CCN(CC1....
399 4NW6 ic50 = 0.004 uM 2NS C23 H20 N4 O4 COc1cc(cc(....
400 4NW5 ic50 = 0.02 uM 2NR C23 H21 F N2 O5 COc1cccc(c....
401 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
402 5D9L ic50 = 0.024 uM 583 C15 H12 N2 O2 c1cc(ccc1c....
403 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
404 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
405 2W7X ic50 = 138 nM D1A C18 H17 N7 O3 [H]/N=C(N)....
406 4A9U - A9U C27 H28 N4 O2 c1ccc(cc1)....
407 2YCF ic50 = 0.7 nM YCF C19 H24 N10 O3 [H]/N=C(N/....
408 4BDI ic50 = 227.7 uM HAU C14 H19 N3 O2 Cc1ccc(nc1....
409 2YCR ic50 = 69.6 nM HCW C23 H28 N10 O C/C(=NNC1=....
410 2WTJ ic50 = 0.7 uM WTJ C16 H20 N4 O3 S CN(C)CCNC(....
411 2YIT ic50 = 0.29 nM YIT C21 H24 N6 O2 CCC/C(=NNC....
412 2W0J ic50 = 240 nM ZAT C19 H24 N10 O [H]/N=C(N)....
413 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
414 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
415 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
416 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
417 2XBJ ic50 = 0.86 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
418 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
419 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
420 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
421 4FG9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
422 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
423 5L2T - 6ZZ C23 H30 N8 O CN(C)C(=O)....
424 5L2S - 6ZV C27 H32 F2 N8 CCN1CCN(CC....
425 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
426 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
427 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
428 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
429 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
430 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
431 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
432 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
433 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
434 3GC0 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
435 3MFU - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
436 3C0H - AMP C10 H14 N5 O7 P c1nc(c2c(n....
437 3C0I - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
438 3MFS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
439 3C0G - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
440 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
441 4OTH ic50 = 9 nM DRN C25 H23 N5 O2 S [H]/N=C(/N....
442 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
443 4APP Ki = 0.064 uM N53 C33 H36 N6 O3 CC1(c2c(c(....
444 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
445 2YAB - AMP C10 H14 N5 O7 P c1nc(c2c(n....
446 2YAA - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
447 3A62 - STU C28 H26 N4 O3 C[C@@]12[C....
448 3WF9 ic50 = 567 nM FS7 C24 H25 N3 O5 S C[C@H]1CCc....
449 3WF8 ic50 = 232 nM F76 C23 H23 N3 O5 S c1ccc2c(c1....
450 4L3L - 5FI C19 H21 F3 N6 CCc1cncnc1....
451 3WE4 ic50 = 15 nM 5FI C19 H21 F3 N6 CCc1cncnc1....
452 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
453 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
454 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
455 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
456 4O0R Ki = 0.036 uM X4Z C25 H28 N8 O S Cc1nc2ccsc....
457 5IME Ki = 4.6 nM 6BZ C22 H22 Cl N7 O2 CC1=NC=CN(....
458 4ZY6 Ki = 5 nM 4T6 C18 H17 Cl N8 c1cc2c(c(c....
459 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
460 4EQC ic50 = 0.008 uM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
461 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
462 5AX9 ic50 = 8 nM 4KT C24 H24 N4 O3 COc1ccc(cc....
463 4EQU - G6I C30 H24 F3 N7 O2 Cc1ccc(cc1....
464 4JR7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
465 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
466 4MWH - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
467 4LFI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
468 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
469 4OBQ ic50 = 0.065 uM 2QT C20 H20 F N5 O c1cc2c(cc1....
470 4U43 Kd = 48 uM 3D8 C11 H9 N5 c1cc(cnc1)....
471 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
472 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
473 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
474 5F9E ic50 = 0.46 nM 5VS C23 H21 N5 O2 CC1(NC(=O)....
475 1XJD Ki = 0.33 nM STU C28 H26 N4 O3 C[C@@]12[C....
476 3M2W ic50 < 0.003 uM L8I C23 H21 F N4 O CN1CC2(C1)....
477 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
478 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
479 5DBX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
480 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
481 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
482 4WNO ic50 = 160 nM 3RF C20 H19 N7 c1ccc2c(c1....
483 4WNP ic50 = 8 nM 3RJ C22 H20 N8 c1ccc2c(c1....
484 5CI7 ic50 = 120 nM 51W C18 H24 I N7 O c1cc(cc(c1....
485 5M56 - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
486 5M4U - 7FC C16 H8 Cl2 O5 c1cc(ccc1C....
487 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
488 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
489 3TXO ic50 = 9 nM 07U C17 H19 N5 CC(C)(CNc1....
490 4USF - 6UI C19 H15 N3 O COc1ccc2cc....
491 1V0P ic50 = 0.13 uM PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
492 1V0O ic50 = 5.5 uM INR C16 H10 N2 O5 S c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 07U; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 07U 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3TXO; Ligand: 07U; Similar sites found: 316
This union binding pocket(no: 1) in the query (biounit: 3txo.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3ETH ATP 0.0009865 0.41392 1.41643
2 4FFG LBS 0.0151 0.4134 1.41643
3 2Z49 AMG 0.02408 0.40108 1.41643
4 4NFN 2KC 0.000002918 0.54396 1.61812
5 4RDL FUC GAL NDG FUC 0.006655 0.42663 1.62338
6 2PYW ADP 0.00000006852 0.5741 1.69972
7 1M0W ANP 0.0007026 0.44986 1.983
8 2CFM AMP 0.002335 0.43577 1.983
9 1E4E ADP 0.00009667 0.46436 2.04082
10 4ZGP ADP 0.003381 0.41297 2.04778
11 1HZP DAO 0.02687 0.40859 2.08955
12 1I7L ATP 0.0001344 0.43221 2.26537
13 3X01 AMP 0.0001503 0.50858 2.26629
14 3WVR AMP 0.0001106 0.48601 2.26629
15 3V4S ATP 0.001042 0.41107 2.26629
16 3ACT BGC 0.01703 0.40476 2.26629
17 4G2R H1L 0.004005 0.40403 2.26629
18 5C1P ADP 0.00005433 0.50627 2.28758
19 5C1P DAL DAL 0.0001613 0.41749 2.28758
20 4JN6 OXL 0.01859 0.40323 2.28758
21 3RE4 TO1 0.0000001135 0.63977 2.32558
22 1ZTH ADP 0.0000001635 0.63227 2.32558
23 1ZP9 ATP 0.0000006995 0.58498 2.32558
24 3OJF NDP 0.02183 0.40829 2.33463
25 3VPC ADP 0.000006975 0.49052 2.48227
26 4CC6 L5Y 0.006613 0.41895 2.51572
27 4R78 AMP 0.000005926 0.56693 2.589
28 3TTM PUT 0.006642 0.42358 2.60116
29 2VDJ HSE 0.0132 0.40648 2.65781
30 2R85 AMP 0.01415 0.41187 2.69461
31 3UDZ ADP 0.000001447 0.58022 2.83286
32 4U98 ACP 0.000283 0.45891 2.83286
33 2QK4 ATP 0.0002503 0.45017 2.83286
34 4AXD ANP 0.00001501 0.40065 2.83286
35 1CKN GTP 0.01481 0.40186 3.0303
36 4OCV ANP 0.00006982 0.47108 3.11615
37 4UWH JXM 0.0003438 0.46383 3.11615
38 4PU5 ANP 0.001308 0.4055 3.11615
39 3I0O ADP 0.00005431 0.51304 3.24484
40 5IQD RIO 0.00002904 0.55092 3.27869
41 5IQD GNP 0.0000271 0.55092 3.27869
42 5K2M ADP 0.00007315 0.51101 3.2967
43 5EXK 5AD 0.01827 0.40359 3.32326
44 3AKK ADP 0.0002442 0.47799 3.38462
45 2YW2 ATP 0.0002224 0.43928 3.39943
46 2QF7 AGS 0.006294 0.42478 3.39943
47 2IO8 ADP 0.0006162 0.40725 3.39943
48 4XYM A12 0.0004078 0.43766 3.47826
49 2ET1 GLV 0.01101 0.41547 3.48259
50 4FE2 ADP 0.009634 0.40248 3.52941
51 4AVB CMP 0.009372 0.40303 3.6036
52 4ME6 ADP 0.0009443 0.46696 3.68272
53 1PK8 ATP 0.00009074 0.42994 3.68272
54 2G50 PYR 0.008526 0.42255 3.68272
55 3T1A 5MA 0.0102 0.40351 3.68272
56 4CS9 AMP 0.009699 0.41286 3.7037
57 1A99 PUT 0.007745 0.42305 3.77907
58 4OUJ LBT 0.008218 0.41559 3.90879
59 3K5I ADP 0.002615 0.40283 3.96601
60 1GSA ADP 0.00003014 0.46101 4.11392
61 1AUX AGS 0.00009363 0.47131 4.18006
62 4BTK DTQ 0.0000003147 0.60745 4.24929
63 2PUL ACP 0.000001255 0.5604 4.24929
64 2YRX AMP 0.0001078 0.51697 4.24929
65 2HGS ADP 0.0009624 0.40564 4.24929
66 3TY5 ATP 0.01193 0.40218 4.24929
67 5TDF ADP 0.00259 0.40177 4.32099
68 3LQV ADE 0.002558 0.43508 4.34783
69 1TZD ADP 0.00000604 0.58495 4.36364
70 3BP1 GUN 0.005869 0.42949 4.48276
71 2AQX ATP 0.0006471 0.42016 4.49827
72 1EHI ADP 0.0008494 0.4267 4.53258
73 4ZS4 ATP 0.0002464 0.44667 4.56026
74 3VPD ANP 0.0002104 0.48541 4.62633
75 2GQR ADP 0.002311 0.42889 4.64135
76 2GQS ADP 0.004644 0.40683 5.06329
77 2ZL7 FUC GAL NGA 0.01015 0.41824 5.08475
78 3PDT ADP 0.001558 0.43428 5.09091
79 4GYI ADP 0.000002698 0.56641 5.09915
80 3DNT ATP 0.001492 0.44957 5.09915
81 1IOW PHY 0.00008389 0.52395 5.22876
82 2BKK ADP 0.0001184 0.478 5.32544
83 3VPB ADP 0.000004866 0.47163 5.35714
84 5I35 ANP 0.000009774 0.52244 5.38244
85 1JXZ BCA 0.02167 0.4004 5.57621
86 1NZY BCA 0.02208 0.4 5.57621
87 3TII ANP 0.0006683 0.44027 5.66572
88 4LH7 1X8 0.002028 0.44876 5.88235
89 4DFU QUE 0.005138 0.42933 5.90062
90 5C4L 4XR 0.0002035 0.50069 5.919
91 5C4L SIS 0.002782 0.446 5.919
92 2IF8 ADP 0.000007191 0.57172 5.94901
93 3ORQ ADP 0.002502 0.40257 5.94901
94 1TQP ATP 0.000008552 0.47165 6.02837
95 5VZ0 ADP 0.00005871 0.48884 6.23229
96 4CYI ATP 0.00001129 0.48739 6.23229
97 4LRJ ANP 0.000005766 0.53221 6.50888
98 4OAV ACP 0.0000002203 0.59308 6.79887
99 2VQD AP2 0.0002968 0.43926 6.79887
100 2VPQ ANP 0.0002431 0.42942 6.79887
101 3TDV GDP 0.000003829 0.52699 6.86275
102 5W2I I3P 0.0000364 0.44551 7.00389
103 5W2I ADP 0.0000364 0.44551 7.00389
104 5COU ATP 0.001715 0.43476 7.05882
105 4IX4 ADP 0.0000029 0.56913 7.14286
106 5GZ9 ANP 0.0000002773 0.62189 7.21311
107 4O1P ANP 0.000000292 0.60894 7.36544
108 5DZT AMP 0.0007559 0.47305 7.36544
109 5MW8 ATP 0.000001982 0.58203 7.64873
110 4PZ6 GMP 0.0008417 0.40719 7.64873
111 4XH0 ADP 0.0000003315 0.64566 8.2153
112 3OCP CMP 0.008122 0.41012 8.63309
113 1W2D ADP 0.00007334 0.50687 8.67924
114 4OUC 5ID 0.0000006683 0.58587 8.68347
115 3PN1 IVH 0.003619 0.40216 9.1195
116 4Q5H ANP 0.00001166 0.5085 9.21053
117 3VOT ADP 0.00004562 0.48956 9.63173
118 1IA9 ANP 0.0003813 0.44101 10.3571
119 2CSN CKI 0.00000002393 0.53535 10.4377
120 5KBE IPH 0.01836 0.40161 10.4803
121 4O4F ATP 0.000655 0.40662 10.4839
122 4O4F IHP 0.0007127 0.40065 10.4839
123 4WW7 AMP 0.00001012 0.48651 10.728
124 3AB4 THR 0.01235 0.40146 11.236
125 5DMZ ADP 0.0000001469 0.5867 11.6147
126 3Q60 ATP 0.0001248 0.48636 11.6147
127 3HAV ATP 0.00003579 0.46467 12.3746
128 4AZW ATP 0.0001752 0.48691 12.4646
129 4AZT LY2 0.0001977 0.4865 12.4646
130 3VHE 42Q 0.00000005249 0.49234 15.2975
131 5LXT ACP 0.0009421 0.40709 15.3846
132 5CKW ANP 0.00000194 0.58147 16.1473
133 5MY8 RXZ 0.00000003746 0.53422 17.5637
134 4QTB 38Z 0.00000004352 0.51597 18.4136
135 5C03 AGS 0.0000206 0.49701 19.0058
136 2PZI AXX 0.00002614 0.52092 19.2635
137 4WOV 3SM 0.00008781 0.49666 20.5047
138 5KO1 6UY 0.000001608 0.55466 21.9081
139 4I94 ANP 0.0000002208 0.59185 22.6667
140 4Y0X ADP 0.000004416 0.54896 22.9333
141 4KBA 1QM 0.0000002147 0.49419 23.8671
142 5W4W 9WG 0.0000001033 0.48124 23.8671
143 4G17 0VN 0.0000007112 0.58465 24.2424
144 4Y85 499 0.00002899 0.50242 24.6988
145 3C1X CKK 0.00001501 0.47593 25.2125
146 2H8H H8H 0.0000003145 0.5734 25.779
147 1Y57 MPZ 0.000006037 0.48133 25.779
148 4FL3 ANP 0.0000004916 0.53402 26.0623
149 1U5R ATP 0.00000005013 0.61945 26.1494
150 4F9C 0SX 0.000000007457 0.65441 26.6289
151 4CRL C1I 0.00000002526 0.4945 26.6289
152 4IJP 1EH 0.00000009741 0.63717 26.9122
153 2WU6 DKI 0.000000004412 0.59319 26.9122
154 5EKO N17 0.000003865 0.48128 27.1955
155 4E93 GUI 0.0000001784 0.47526 27.1955
156 5UIU 8CG 0.0000000807 0.6622 27.2446
157 2B9J ADP 0.000000005801 0.66024 27.4788
158 2B9I ADP 0.00000000285 0.65694 27.4788
159 3TTI KBI 0.0000008963 0.47991 27.4788
160 5EOB 5QQ 0.00005309 0.55483 27.5862
161 2B9F ADP 0.000000006889 0.63987 28.0453
162 1Q8Y ADE 0.0000002524 0.63346 28.0453
163 5AWM ANP 0.0000001629 0.63234 28.0453
164 1Q8Y ADP 0.00000002177 0.59093 28.0453
165 5T8O 76Z 0.00000000839 0.60508 28.0802
166 5X8I SQZ 0.00000000007981 0.71634 28.3237
167 1VJY 460 0.00000001174 0.4985 28.3828
168 3H9R TAK 0.000003695 0.57689 28.4848
169 4OH4 ANP 0.00000008224 0.59632 28.5285
170 4ASE AV9 0.0000002991 0.63042 28.6119
171 4IDT T28 0.00000004424 0.62237 28.6119
172 5LPZ ADP 0.00000009109 0.59503 28.6145
173 1CM8 ANP 0.0000001945 0.59343 28.8952
174 4H3P ANP 0.000000543 0.56339 28.8952
175 4H3Q ANP 0.0000005102 0.52252 28.8952
176 3VRY B43 0.0000005458 0.50161 28.8952
177 3LXN MI1 0.000000003115 0.62108 28.9308
178 4M69 ANP 0.000007025 0.5514 29.0735
179 3PTG 932 0.0000001308 0.58192 29.1785
180 4P5Z Q7M 0.000001807 0.42017 29.1785
181 4BHN BH9 0.000000008124 0.60661 29.3413
182 5USZ SKE 0.00001762 0.44405 29.4118
183 4LOO SB4 0.00001634 0.50195 29.745
184 3PP0 03Q 0.0000001345 0.50987 29.8817
185 5HCY 60D 0.000001221 0.40737 29.9094
186 3ZRM ZRM 0.00000009768 0.59359 30.0283
187 3E7O 35F 0.0000003399 0.45776 30.0283
188 4BKJ STI 0.00008653 0.42467 30.1587
189 3ALN ANP 0.000001713 0.51893 30.2752
190 3F7Z 34O 0.000000009433 0.6356 30.2857
191 4U44 3D9 0.0000002377 0.61301 30.4217
192 5BYZ 4WE 0.0000007776 0.4644 30.4598
193 4GJ3 0XP 0.000000002865 0.51907 30.4636
194 4UX9 ANP 0.00000003692 0.5843 30.5949
195 4NM5 ADP 0.0000001631 0.53659 30.5949
196 4IZY 1J2 0.0000009179 0.52781 30.5949
197 5JGA 6KC 0.00000002139 0.49527 30.7937
198 1O9U ADZ 0.000001113 0.60454 30.8571
199 3PLS ANP 0.000000944 0.58249 30.8725
200 3GNI ATP 0.000004607 0.50357 30.8782
201 3LXK MI1 0.00000006702 0.51266 30.8869
202 4EUU BX7 0.0000001949 0.50698 31.348
203 5HX8 66P 0.00000003373 0.52814 31.457
204 2QLU ADE 0.000004388 0.58753 31.5287
205 5HES 032 0.0000004246 0.61052 31.5961
206 3NW7 LGV 0.000005899 0.59497 31.5961
207 4E1Z 0MX 0.00000006664 0.54961 31.6151
208 4YLL 4E3 0.00000002568 0.67011 31.728
209 4NST ADP 0.00000004759 0.64487 31.9088
210 4AG8 AXI 0.0000001082 0.4515 31.962
211 4K33 ACP 0.000000138 0.57384 32
212 3GC8 B45 0.000006094 0.4917 32.0113
213 2PVF ACP 0.00000002829 0.63037 32.0359
214 5HVJ ANP 0.00000001627 0.71546 32.0635
215 5LPB ADP 0.00000004178 0.66029 32.0946
216 1K3A ACP 0.0000007257 0.57298 32.107
217 2WQN ADP 0.00000361 0.56057 32.2581
218 5EFQ ADP 0.0000000428 0.60844 32.2767
219 2JLD AG1 0.00000001612 0.49203 32.2946
220 1JPA ANP 0.0000001798 0.44141 32.6923
221 5MJA 7O3 0.0000007959 0.58245 32.7869
222 2OO8 RAJ 0.0002171 0.43105 32.8076
223 3UIM ANP 0.0000004198 0.56785 32.8221
224 1OPK P16 0.0000002847 0.46749 32.8612
225 5NKB 8ZT 0.0000007619 0.41495 33.0065
226 5U6C 7YS 0.000002297 0.50711 33.0159
227 5JKG 6LF 0.000000339 0.43497 33.119
228 3GQI ACP 0.0000001265 0.58739 33.1288
229 4YZC STU 0.00000001037 0.71836 33.1445
230 3SRV S19 0.000000003282 0.69392 33.213
231 2X2M X2M 0.000000005568 0.59887 33.4395
232 1U59 STU 0.000000004614 0.64751 33.4495
233 2Y6O 1N1 0.0000008999 0.51875 33.677
234 5JFS 6K0 0.000001088 0.62431 33.7662
235 4QMN DB8 0.0000008811 0.43879 33.871
236 4XV1 904 0.000000214 0.64819 33.9041
237 2OFV 242 0.000001835 0.6065 33.935
238 5LXC 7AA 0.00000000006878 0.76534 33.9943
239 5TA6 79D 0.000006221 0.44473 33.9943
240 2XVD AS6 0.000003832 0.46014 34.106
241 4EWH T77 0.00000007089 0.51227 34.1818
242 4Y93 746 0.000006542 0.46252 34.2776
243 4CLI 5P8 0.000002147 0.61417 34.5566
244 5UR1 YY9 0.000002276 0.44639 34.7267
245 4G31 0WH 0.0000008589 0.43827 34.7826
246 3RI1 3RH 0.000000413 0.50138 34.8243
247 5TO8 7FM 0.000003097 0.41711 35.1064
248 4AT3 LTI 0.00001594 0.43188 35.1171
249 4Y8D 49J 0.00000001328 0.62727 35.2941
250 4N70 2HX 0.000000003917 0.43025 35.3659
251 5VCV 1N1 0.00000001762 0.55925 35.3698
252 5H2U 1N1 0.00001389 0.50519 35.5805
253 1BYG STU 0.00000006816 0.63049 35.6115
254 4CQE CQE 0.000000376 0.53112 35.6115
255 3DLS ADP 0.000000003748 0.68719 35.8209
256 3KRL KRL 0.0000007189 0.52339 35.8209
257 5DA3 58V 0.0000005485 0.60741 35.8491
258 5M06 ADP 0.000001428 0.57103 35.8696
259 5CEO 50D 0.000005852 0.54955 36
260 5UOX 8GY 0.00000001082 0.5898 36.5314
261 3EKK GS2 0.0000008158 0.43226 36.8078
262 3BU5 ATP 0.00000005471 0.60384 36.9281
263 3CY2 MB9 0.000000001107 0.61369 36.9427
264 1ZY5 ANP 0.00000181 0.5517 36.9637
265 4CSV STI 0.00001991 0.46145 37.0909
266 4A4X JUP 0.0000007336 0.48606 37.276
267 5VC5 96M 0.0000006105 0.49125 37.3702
268 3ORK AGS 0.000002279 0.481 37.6206
269 4XLI 1N1 0.0000007214 0.57058 37.6866
270 2HK5 1BM 0.0000005179 0.53984 37.7778
271 4X7Q 3YR 0.00000000007876 0.71811 37.8205
272 3KN5 ANP 0.0000001081 0.61014 37.8462
273 3HMO STU 0.0000006148 0.57376 38.0117
274 4YMJ 4EJ 0.00000004547 0.69097 38.1579
275 4U0I 0LI 0.000001722 0.60046 38.7302
276 3IGO ANP 0.00000009217 0.55747 38.8102
277 3HZT J60 0.0000001789 0.63042 39.0935
278 3SXF BK5 0.00000006243 0.46846 39.3768
279 4JDI ANP 0.000000009721 0.60525 39.5954
280 3KMW ATP 0.0001609 0.46927 39.8524
281 3SXS PP2 0.0000002366 0.54959 39.9254
282 2RIO ADP 0.0000002387 0.59193 39.9433
283 2F57 23D 0.000003528 0.55335 40.3785
284 4BFM ANP 0.00000001577 0.5995 40.4192
285 5DH3 5BS 0.000001082 0.52911 40.9524
286 5N87 N66 0.0000004709 0.44355 41.2141
287 2WEL K88 0.000001417 0.50902 41.5902
288 2HY0 306 0.0000001808 0.62054 41.6149
289 5FBN 5WF 0.00001281 0.41334 41.6974
290 5IH9 6BF 0.00000009229 0.46163 41.791
291 2A19 ANP 0.0000009444 0.59625 42.2535
292 4YZN 4K5 0.000000003895 0.59281 42.5087
293 4TWP AXI 0.0000006473 0.40801 42.8044
294 4I6H 1C8 0.00000476 0.52136 42.8571
295 3SLS ANP 0.000001001 0.51802 43.0921
296 3O0G 3O0 0.00000001375 0.66572 44.5205
297 1UNH IXM 0.00000004104 0.62914 44.5205
298 5A6N U7E 0.0000005373 0.59997 44.8763
299 2J7T 274 0.000004912 0.44457 45.0331
300 2ZV2 609 0.0000000006515 0.74573 45.302
301 4WNK 453 0.00000004832 0.50496 45.6091
302 4D2S DYK 0.0000008452 0.58965 45.7746
303 2X4Z X4Z 0.000001925 0.60373 46.2838
304 5HQ0 LZ9 0.000000001403 0.63506 46.3576
305 4L9I 8PR 0.000003313 0.54257 46.7422
306 5LXM ADP 0.00000007931 0.61209 46.9965
307 4CFU 2WC 0.00000006297 0.63204 47.5248
308 5L8L ADP 0.0000008712 0.59791 47.7193
309 5G1X ADP 0.0000003326 0.58586 47.7193
310 4BCQ TJF 0.0000005683 0.60668 47.8405
311 4BCM T7Z 0.000001547 0.52641 47.8405
312 4BCN T9N 0.00000006413 0.64129 48
313 5LMK 6ZK 0.000006327 0.54193 48.4848
314 2BPM 529 0.00000007987 0.41573 48.8673
315 5UKL SIX 0.000008503 0.56129 49.8584
316 3PVW QRX 0.00000003564 0.53219 49.8584
317 2B9H ADP 0.000000002374 0.70804 50
318 3AQV TAK 0.00001349 0.533 50
319 3E5A VX6 0.000009335 0.46713 50
Pocket No.: 2; Query (leader) PDB : 3TXO; Ligand: 07U; Similar sites found: 417
This union binding pocket(no: 2) in the query (biounit: 3txo.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1UO5 PIH 0.008122 0.44692 None
2 1UO4 PIH 0.006721 0.44189 None
3 4F4S EFO 0.0009197 0.43715 None
4 2VKL MLT 0.01892 0.4187 None
5 4NPT 017 0.001857 0.41387 None
6 2BOI MFU 0.006449 0.40289 None
7 2C5S AMP 0.002665 0.41301 0.849858
8 1Y9Q MED 0.002321 0.4332 1.04167
9 3QP4 HL0 0.0001193 0.43799 1.0989
10 1FP2 SAH 0.001371 0.40893 1.13636
11 2W8Q SIN 0.001136 0.45416 1.41643
12 4WBD ADP 0.001569 0.44784 1.41643
13 3IHB GLU 0.00275 0.43683 1.41643
14 2DKH FAD 0.003487 0.42109 1.41643
15 2DKH 3HB 0.005812 0.41896 1.41643
16 4WBD CIT 0.01503 0.40954 1.41643
17 2W1A TSA 0.000693 0.40728 1.41643
18 4KCF FMN 0.002849 0.40208 1.41643
19 3LTW HLZ 0.00206 0.43545 1.42857
20 4JWX 1N4 0.003706 0.41264 1.42857
21 4OB6 S2T 0.0002683 0.42704 1.46628
22 3BLI ACO 0.004497 0.4024 1.48368
23 2GDZ NAD 0.0009845 0.43852 1.49813
24 1I0Z OXM 0.001546 0.46486 1.5015
25 1E7S NAP 0.001626 0.43281 1.55763
26 4KGM ATP 0.0009172 0.42016 1.63265
27 4Q0A 4OA 0.0001815 0.41811 1.65563
28 1AUA BOG 0.003387 0.41423 1.68919
29 1PEA ACM 0.001357 0.45872 1.69972
30 2YIV NBN 0.002405 0.43946 1.69972
31 1P9B HDA 0.001766 0.43177 1.69972
32 2YIV YIV 0.01788 0.40597 1.69972
33 1P9B GDP 0.0009553 0.40104 1.69972
34 3E6J DR2 0.03042 0.40446 1.74672
35 1V6A TRE 0.003106 0.42149 1.80723
36 1JA9 NDP 0.02005 0.41597 1.82482
37 1NNS ASP 0.003258 0.40461 1.84049
38 1YOE RIB 0.0009071 0.43133 1.86335
39 3C1O NAP 0.003064 0.41199 1.86916
40 4F2Q QUS 0.0003921 0.42828 1.93798
41 4LSJ LSJ 0.002242 0.41184 1.93798
42 1IYE PGU 0.002572 0.42371 1.94175
43 2ZWS PLM 0.001892 0.48107 1.983
44 4RJK PYR 0.0009832 0.4653 1.983
45 4O8A 2OP 0.004039 0.44439 1.983
46 1Q3Q ANP 0.01042 0.42188 1.983
47 1FBL HTA 0.001476 0.41765 1.983
48 3DG6 MUC 0.0008204 0.41687 1.983
49 4BAS GNP 0.002207 0.4121 1.983
50 1GPJ CIT 0.009151 0.40726 1.983
51 3NKS ACJ 0.001239 0.40391 1.983
52 4COQ SAN 0.000229 0.47691 2.02429
53 1E4E PHY 0.0007047 0.41301 2.04082
54 2FR6 CTN 0.0003286 0.41162 2.05479
55 2JFV FLC 0.003563 0.4251 2.06186
56 1T3D CYS 0.00767 0.41668 2.07612
57 1AX2 NDG GAL 0.00488 0.40779 2.09205
58 9LDB OXM 0.0008711 0.48745 2.10843
59 9LDT OXM 0.001045 0.48339 2.10843
60 2Q3M MLA 0.0001476 0.51485 2.14724
61 1NML CIT 0.002314 0.42093 2.14724
62 2XI7 XI7 0.000101 0.54964 2.17391
63 2HFK E4H 0.000761 0.44048 2.19436
64 1TDF FAD 0.00122 0.45342 2.21519
65 1TDF NAP 0.004329 0.44603 2.21519
66 3EW2 BTN 0.003208 0.40985 2.22222
67 1WNG SAH 0.000292 0.40571 2.26415
68 3QP6 HL6 0.002188 0.4017 2.26415
69 4GYW UDP 0.001734 0.43171 2.26629
70 4ARF IP8 GLY PRO ALA 0.001201 0.41339 2.26629
71 2Q09 DI6 0.00294 0.41134 2.26629
72 3QV9 QV7 0.005705 0.41041 2.26629
73 1QZZ SAM 0.001462 0.40793 2.26629
74 3O2K DST 0.00536 0.40614 2.26629
75 3JDW ORN 0.001988 0.40552 2.26629
76 4WX0 HXD 0.001182 0.40456 2.28137
77 2C2A ADP 0.0006146 0.40669 2.32558
78 2V7T SAH 0.007315 0.44363 2.34114
79 3L0E G58 0.00002686 0.40019 2.37154
80 1P72 THM 0.0007054 0.44181 2.39521
81 3PXP MYR 0.0008494 0.40303 2.39726
82 4FGC PQ0 0.00635 0.40845 2.42424
83 1GVF PGH 0.003525 0.41352 2.44755
84 3P7I P7I 0.001024 0.43526 2.49221
85 3GJB AKG 0.001962 0.41822 2.50784
86 1LTH FBP 0.005538 0.41676 2.50784
87 3ICV NAG 0.039 0.40046 2.53165
88 3ZPG 5GP 0.002635 0.45349 2.54958
89 1YHM AHD 0.0007188 0.44814 2.54958
90 4WVH ASP HIS ASP ALA HIS ALA 0.0006252 0.43766 2.54958
91 2Z9V PXM 0.001017 0.43539 2.54958
92 2NLI FMN 0.005266 0.43441 2.54958
93 2NLI LAC 0.006965 0.43069 2.54958
94 3DAG FEG 0.001378 0.42676 2.54958
95 4N02 FNR 0.007003 0.42621 2.54958
96 2YVF FAD 0.0104 0.42396 2.54958
97 3PC3 P1T 0.00007597 0.41825 2.54958
98 4DXJ IPE 0.0003754 0.40937 2.54958
99 4AQL TXC 0.0006135 0.4086 2.54958
100 2YVF NAD 0.02707 0.4068 2.54958
101 3MTW M3R 0.001236 0.40431 2.54958
102 3CL7 HYN 0.001214 0.42716 2.5974
103 4JLV ADP 0.01328 0.43086 2.60223
104 3PMD 11A 0.002556 0.40861 2.61438
105 3ZF8 GDP 0.001066 0.42301 2.62295
106 1OIK AKG 0.001786 0.43815 2.65781
107 1Z42 HBA 0.003742 0.45992 2.66272
108 1Z44 NPO 0.0101 0.44181 2.66272
109 3CEV ARG 0.0002055 0.45656 2.67559
110 1V7R CIT 0.00209 0.46795 2.68817
111 4EXO PYR 0.002429 0.44685 2.73973
112 2YBQ SAH 0.001274 0.41896 2.73973
113 1SOW OXL 0.005439 0.43804 2.7439
114 2QLX RM4 0.003713 0.43093 2.77778
115 3OZG SSI 0.000267 0.43684 2.8
116 1H16 PYR 0.0004803 0.47992 2.83286
117 1Y42 TYR 0.001183 0.43272 2.83286
118 2Q8H TF4 0.00701 0.43262 2.83286
119 1H16 DTL 0.01035 0.42429 2.83286
120 1ZFJ IMP 0.011 0.41148 2.83286
121 4WOE 3S5 0.03538 0.41014 2.83286
122 4EPL JAI 0.001522 0.4005 2.83286
123 1B5E DCM 0.004478 0.40418 2.84553
124 3LST SAH 0.001174 0.41133 2.87356
125 3U1T MLI 0.0003456 0.47749 2.91262
126 1UF5 CDT 0.002328 0.41015 2.9703
127 4B9E FAH 0.009935 0.41159 2.99003
128 1QH9 LAC 0.0007288 0.45506 3.01724
129 2HW1 ANP 0.0001296 0.41001 3.02013
130 2HW1 FRU 0.008467 0.4032 3.02013
131 3KYF 5GP 5GP 0.0004038 0.43898 3.0303
132 1G8S MET 0.0019 0.43698 3.04348
133 1XX4 BAM 0.002894 0.41983 3.06513
134 3GTD MLI 0.00224 0.42745 3.11615
135 3DDN HPV 0.00007043 0.41866 3.11615
136 2ZJ5 ADP 0.004211 0.41595 3.11615
137 3AHC TPP 0.004054 0.41469 3.11615
138 4G1V FAD 0.007922 0.40074 3.11615
139 4K30 NLG 0.001489 0.42868 3.125
140 3TKA SAM 0.0002054 0.40542 3.17003
141 2Y7P SAL 0.0005218 0.44711 3.21101
142 3GEG NAD 0.003517 0.41429 3.23887
143 3I0O SMI 0.003446 0.4196 3.24484
144 2HGZ PBF 0.0008445 0.43311 3.26797
145 2P69 PLP 0.001718 0.43228 3.26797
146 4TMK T5A 0.001621 0.43286 3.28639
147 1UAY ADN 0.001372 0.40892 3.30579
148 3FPZ AHZ 0.00654 0.44166 3.37423
149 4USS GSH 0.003041 0.41612 3.38462
150 1RYI GOA 0.0006628 0.5075 3.39943
151 3Q9T FAY 0.000553 0.45888 3.39943
152 1YBH P22 0.001108 0.42237 3.39943
153 1WDA BAG 0.001574 0.42197 3.39943
154 5FIT AP2 0.002905 0.40177 3.40136
155 1YFZ IMP 0.002173 0.428 3.41463
156 4W6Z ETF 0.008252 0.42914 3.45821
157 1HFA PIO 0.01007 0.44891 3.46021
158 3BY8 MLT 0.001301 0.45151 3.52113
159 4IXW IXW 0.00438 0.40455 3.54331
160 4JCA CIT 0.009239 0.43477 3.59281
161 1DXY COI 0.007888 0.4301 3.6036
162 1LYX PGA 0.001574 0.40679 3.62903
163 1VR0 3SL 0.0003034 0.44994 3.64372
164 1H8P PC 0.01082 0.42335 3.66972
165 1ZUW DGL 0.001164 0.42709 3.67647
166 3L24 GOA 0.001014 0.47384 3.68272
167 1E2S CSN 0.0001501 0.44313 3.68272
168 1X54 4AD 0.0006713 0.43687 3.68272
169 2C31 TZD 0.007959 0.43514 3.68272
170 2C31 ADP 0.008982 0.43228 3.68272
171 1GJW MAL 0.0006783 0.43045 3.68272
172 1GJW GLC 0.004758 0.42606 3.68272
173 4HA6 PXM 0.002536 0.42518 3.68272
174 3CXO 1N5 0.002853 0.42195 3.68272
175 4R33 TRP 0.00372 0.41999 3.68272
176 4R33 SAH 0.00372 0.41999 3.68272
177 3UH0 TSB 0.003906 0.40638 3.68272
178 2I4O ATP 0.003901 0.40165 3.68272
179 1PR9 NAP 0.0007084 0.44829 3.68852
180 4RPM HXC 0.04529 0.40628 3.69458
181 3H22 B53 0.001409 0.41841 3.7037
182 3R51 MMA 0.0104 0.4242 3.75
183 3L6R MLI 0.002143 0.44171 3.75723
184 1JN2 SFP 0.04973 0.40605 3.79747
185 1P9P SAH 0.001419 0.42108 3.83142
186 3CBG 4FE 0.001399 0.4769 3.87931
187 3CBG FER 0.002057 0.45876 3.87931
188 1Y8O ADP 0.003516 0.40336 3.90625
189 5EQU AKG 0.02154 0.40214 3.93443
190 1B74 DGN 0.002778 0.4441 3.93701
191 2F01 BTQ 0.009323 0.42856 3.93701
192 2F01 BTN 0.01037 0.42657 3.93701
193 3KJI ADP 0.002165 0.40419 3.93701
194 1RYD GLC 0.0002382 0.47616 3.96601
195 2ZYF AKG 0.000585 0.43879 3.96601
196 1PX8 XYP 0.002092 0.42869 3.96601
197 4C2G ALA ALA ALA ALA 0.001275 0.42555 3.96601
198 1A59 CIT 0.008791 0.414 3.96601
199 3K5X P8D 0.002041 0.41231 3.96601
200 4LO6 SIA GAL 0.01507 0.40636 3.96601
201 2E1A MSE 0.0001702 0.45977 4
202 3IOI 1GW 0.003943 0.41775 4.02685
203 1EYQ NAR 0.004783 0.40305 4.05405
204 1M1B SPV 0.0009972 0.44218 4.0678
205 1VQ2 DDN 0.0003324 0.41709 4.14508
206 1A27 EST 0.0002427 0.42736 4.15225
207 1FW1 GSH 0.001518 0.40736 4.16667
208 3UBW 6SP 0.0002295 0.55367 4.21456
209 1SQ5 PAU 0.001451 0.42913 4.22078
210 1SQ5 ADP 0.0006694 0.42518 4.22078
211 1Y2W NAG 0.0006524 0.45715 4.22535
212 2HGS GSH 0.0004354 0.42667 4.24929
213 4OYA 1VE 0.02631 0.42223 4.24929
214 1KBJ FMN 0.002024 0.42042 4.24929
215 2CE7 ADP 0.002013 0.40298 4.24929
216 4BG1 IVL 0.000293