Receptor
PDB id Resolution Class Description Source Keywords
3TII 2.5 Å NON-ENZYME: OTHER TUBULIN TYROSINE LIGASE XENOPUS (SILURANA) TROPICALIS ATP-GRASP LIGASE TUBULIN TYROSINATION
Ref.: TUBULIN TYROSINE LIGASE STRUCTURE REVEALS ADAPTATIO ANCIENT FOLD TO BIND AND MODIFY TUBULIN. NAT.STRUCT.MOL.BIOL. V. 18 1250 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP B:710;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
ANP MG A:700;
Valid;
none;
submit data
526.471 n/a [P+](...
MG A:381;
A:382;
B:381;
B:382;
B:383;
B:384;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3TII 2.5 Å NON-ENZYME: OTHER TUBULIN TYROSINE LIGASE XENOPUS (SILURANA) TROPICALIS ATP-GRASP LIGASE TUBULIN TYROSINATION
Ref.: TUBULIN TYROSINE LIGASE STRUCTURE REVEALS ADAPTATIO ANCIENT FOLD TO BIND AND MODIFY TUBULIN. NAT.STRUCT.MOL.BIOL. V. 18 1250 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 3TII - ANP MG n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 3TII - ANP MG n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 3TII - ANP MG n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Ligand no: 2; Ligand: ANP MG; Similar ligands found: 299
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP MG 1 1
2 ADP MG 0.797468 0.959459
3 BEF ADP 0.765432 0.934211
4 ADP BEF 0.765432 0.934211
5 ATP MG 0.759036 0.959459
6 ADP PO3 0.746988 0.918919
7 AMP MG 0.721519 0.945946
8 ALF ADP 0.712644 0.873418
9 ADP ALF 0.712644 0.873418
10 ADP VO4 0.704545 0.933333
11 VO4 ADP 0.704545 0.933333
12 A 0.675 0.893333
13 AMP 0.675 0.893333
14 A2D 0.670732 0.894737
15 GAP 0.670455 0.871795
16 ADP 0.666667 0.894737
17 ADP BMA 0.659574 0.871795
18 BA3 0.654762 0.894737
19 AU1 0.651163 0.921053
20 ABM 0.650602 0.87013
21 AP5 0.647059 0.894737
22 B4P 0.647059 0.894737
23 ATP A A A 0.642857 0.906667
24 AN2 0.639535 0.907895
25 AP2 0.635294 0.860759
26 A12 0.635294 0.860759
27 DAL AMP 0.634409 0.883117
28 ANP 0.633333 0.921053
29 M33 0.632184 0.883117
30 SRA 0.626506 0.848101
31 ACP 0.625 0.871795
32 ATP 0.625 0.894737
33 A A 0.618557 0.894737
34 5FA 0.617977 0.894737
35 AQP 0.617977 0.894737
36 APR 0.617977 0.894737
37 APC 0.617977 0.860759
38 PRX 0.617977 0.848101
39 AR6 0.617977 0.894737
40 CA0 0.613636 0.871795
41 ADX 0.613636 0.809524
42 SAP 0.611111 0.85
43 AD9 0.611111 0.896104
44 AGS 0.611111 0.85
45 50T 0.606742 0.883117
46 MYR AMP 0.606061 0.8
47 AR6 AR6 0.601942 0.894737
48 MAP 0.6 0.947368
49 TAT 0.597826 0.860759
50 ACQ 0.597826 0.871795
51 ADV 0.593407 0.860759
52 RBY 0.593407 0.860759
53 AHZ 0.590476 0.8
54 TYR AMP 0.588235 0.860759
55 ATF 0.585106 0.860759
56 AMP DBH 0.582524 0.848101
57 SRP 0.578947 0.860759
58 5AL 0.574468 0.883117
59 ALF ADP 3PG 0.574074 0.841463
60 AF3 ADP 3PG 0.574074 0.841463
61 LA8 ALF 3PG 0.574074 0.841463
62 5AS 0.573034 0.764045
63 A22 0.56701 0.883117
64 SON 0.566667 0.860759
65 5SV 0.561224 0.807229
66 ARG AMP 0.560748 0.790698
67 OAD 0.56 0.871795
68 A1R 0.555556 0.839506
69 4AD 0.555556 0.873418
70 ADQ 0.555556 0.871795
71 AMO 0.555556 0.860759
72 AHX 0.55 0.851852
73 DLL 0.55 0.883117
74 NB8 0.54902 0.851852
75 3OD 0.54902 0.871795
76 AOC 0.545455 0.779221
77 OOB 0.545455 0.883117
78 25A 0.545455 0.894737
79 8QN 0.545455 0.883117
80 PO4 PO4 A A A A PO4 0.544554 0.88
81 XYA 0.544304 0.776316
82 ADN 0.544304 0.776316
83 RAB 0.544304 0.776316
84 NAD IBO 0.54386 0.873418
85 LPA AMP 0.541284 0.8
86 PAJ 0.54 0.819277
87 WAQ 0.539216 0.839506
88 LAD 0.539216 0.819277
89 4TA 0.53913 0.790698
90 NAD 0.53913 0.907895
91 NAJ PZO 0.538462 0.851852
92 3DH 0.534884 0.734177
93 00A 0.534653 0.839506
94 TXA 0.533981 0.860759
95 1ZZ 0.533981 0.8
96 ME8 0.533981 0.8
97 BIS 0.533981 0.839506
98 FYA 0.533981 0.858974
99 5N5 0.530864 0.753247
100 A3D 0.529915 0.896104
101 3UK 0.529412 0.871795
102 25L 0.528846 0.883117
103 AFH 0.527778 0.819277
104 5CD 0.52439 0.763158
105 A4D 0.52439 0.753247
106 PR8 0.524272 0.809524
107 9SN 0.52381 0.829268
108 G5A 0.520833 0.764045
109 NAQ 0.520661 0.851852
110 JB6 0.519231 0.839506
111 PTJ 0.519231 0.829268
112 FA5 0.518868 0.860759
113 YAP 0.518868 0.85
114 AMP NAD 0.516393 0.884615
115 XAH 0.514019 0.821429
116 48N 0.513514 0.829268
117 YLP 0.513514 0.781609
118 G A A A 0.512821 0.829268
119 NAE 0.512397 0.873418
120 Z5A 0.512195 0.804598
121 PAP 0.510417 0.881579
122 NAJ PYZ 0.508197 0.876543
123 EP4 0.505882 0.716049
124 A3N 0.505495 0.725
125 A5A 0.50505 0.790698
126 TSB 0.504951 0.781609
127 NVA LMS 0.504854 0.766667
128 G3A 0.504587 0.829268
129 OMR 0.504425 0.790698
130 ZID 0.504065 0.896104
131 SSA 0.5 0.764045
132 YLC 0.5 0.8
133 A A A 0.5 0.883117
134 6RE 0.5 0.722892
135 DTA 0.5 0.746835
136 G5P 0.5 0.829268
137 M2T 0.5 0.719512
138 7MD 0.5 0.821429
139 YLB 0.5 0.781609
140 U A G G 0.495798 0.839506
141 DND 0.495575 0.884615
142 UP5 0.495575 0.85
143 NXX 0.495575 0.884615
144 NAI 0.495575 0.839506
145 GTA 0.495495 0.821429
146 TAD 0.495495 0.819277
147 4UV 0.495413 0.85
148 NSS 0.495146 0.784091
149 VMS 0.49505 0.772727
150 54H 0.49505 0.772727
151 52H 0.49505 0.764045
152 A3P 0.494624 0.893333
153 MTA 0.494253 0.734177
154 TXE 0.491228 0.839506
155 5CA 0.490196 0.764045
156 53H 0.490196 0.764045
157 J7C 0.48913 0.710843
158 7D5 0.488636 0.810127
159 139 0.487179 0.809524
160 4TC 0.486957 0.829268
161 AP0 0.486957 0.829268
162 4UU 0.486486 0.85
163 2A5 0.484536 0.825
164 S4M 0.483871 0.655556
165 7D3 0.483871 0.8125
166 AYB 0.483051 0.772727
167 A U 0.482759 0.85
168 TXD 0.482456 0.839506
169 6V0 0.482456 0.829268
170 NAX 0.482456 0.809524
171 P5A 0.481132 0.731183
172 DSZ 0.480769 0.764045
173 LSS 0.480769 0.747253
174 NDE 0.48062 0.884615
175 ATR 0.479592 0.868421
176 A2P 0.478723 0.88
177 MAO 0.478723 0.744186
178 TYM 0.478261 0.860759
179 LAQ 0.477876 0.8
180 3AM 0.477778 0.855263
181 YLA 0.474576 0.781609
182 UPA 0.474138 0.839506
183 7MC 0.474138 0.802326
184 NDC 0.473282 0.851852
185 ZAS 0.472527 0.794872
186 LEU LMS 0.471698 0.766667
187 A4P 0.470085 0.764045
188 4UW 0.469565 0.819277
189 GJV 0.468085 0.714286
190 KAA 0.46729 0.73913
191 GSU 0.46729 0.764045
192 IOT 0.466102 0.772727
193 PPS 0.465347 0.788235
194 7D4 0.463918 0.8125
195 5AD 0.463415 0.706667
196 BTX 0.46281 0.781609
197 NMN AMP PO4 0.46281 0.85
198 COD 0.46281 0.755556
199 DSH 0.462366 0.690476
200 T5A 0.462185 0.781609
201 ADJ 0.462185 0.790698
202 AV2 0.460784 0.846154
203 YSA 0.459459 0.764045
204 5X8 0.459184 0.725
205 BT5 0.459016 0.772727
206 CNA 0.458333 0.884615
207 IMO 0.457447 0.855263
208 SAM 0.455446 0.678161
209 V3L 0.455446 0.894737
210 A2R 0.451923 0.883117
211 N01 0.451613 0.883117
212 OVE 0.451613 0.8125
213 2AM 0.450549 0.844156
214 NAD BBN 0.449275 0.86747
215 ITT 0.44898 0.844156
216 MHZ 0.44898 0.685393
217 U G A 0.448529 0.8
218 NEC 0.446809 0.6875
219 A3G 0.446809 0.7375
220 6C6 0.445545 0.814815
221 YLY 0.444444 0.772727
222 SFG 0.444444 0.7125
223 NAD CJ3 0.442857 0.837209
224 S7M 0.442308 0.678161
225 SMM 0.442308 0.674157
226 6IA 0.441176 0.776471
227 CNV FAD 0.440559 0.73913
228 ENQ 0.440367 0.868421
229 U A C C 0.44 0.839506
230 A7D 0.438776 0.7375
231 6AD 0.436893 0.819277
232 SA8 0.435644 0.674419
233 DZD 0.435484 0.819277
234 N0B 0.434109 0.781609
235 M24 0.433071 0.831325
236 71V 0.43299 0.817073
237 GDP MG 0.432692 0.875
238 PLP AAD 0.432 0.747253
239 SAI 0.431373 0.719512
240 SAH 0.431373 0.707317
241 NA7 0.431193 0.860759
242 4YB 0.431034 0.747253
243 DAT 0.43 0.8125
244 GEK 0.429907 0.722892
245 WSA 0.428571 0.772727
246 649 0.428571 0.731183
247 FAD NBT 0.427586 0.736842
248 U A A U 0.427481 0.8625
249 EAD 0.427481 0.809524
250 7C5 0.426087 0.756098
251 0UM 0.425926 0.666667
252 FAD CNX 0.425676 0.68
253 P1H 0.425373 0.790698
254 Y3J 0.425287 0.688312
255 A3S 0.424242 0.746835
256 7D7 0.423529 0.705128
257 EEM 0.423077 0.697674
258 NAP 0.423077 0.896104
259 ARU 0.422018 0.776471
260 DAL FAD PER 0.421769 0.793103
261 A5D 0.421569 0.746835
262 TAP 0.419847 0.8625
263 2SA 0.419048 0.8375
264 GDP AF3 0.418182 0.8
265 NAD TDB 0.417219 0.699029
266 D5M 0.416667 0.810127
267 AVV 0.416667 0.829268
268 GTP MG 0.416667 0.875
269 DA 0.416667 0.810127
270 6K6 0.416667 0.857143
271 NA0 0.416667 0.884615
272 NAD NDT 0.416107 0.75
273 NHD 0.416 0.883117
274 A3T 0.415842 0.75641
275 GDP BEF 0.415094 0.853659
276 NIA 0.414894 0.82716
277 DTP 0.413462 0.8125
278 3AT 0.413462 0.87013
279 P33 FDA 0.413333 0.715789
280 P6G FDA 0.413333 0.73913
281 FDA 0.413043 0.755556
282 AAM 0.412371 0.893333
283 A U C C 0.411765 0.829268
284 AAT 0.409524 0.674419
285 PAX 0.409091 0.790698
286 FB0 0.408759 0.731183
287 AMZ 0.408602 0.820513
288 TM1 0.40708 0.77907
289 APC G U 0.40625 0.795181
290 PGS 0.405941 0.817073
291 K15 0.405405 0.651685
292 A6D 0.405405 0.75
293 0WD 0.404762 0.829268
294 BEF GDP 0.40367 0.843373
295 FAD NBA 0.401274 0.686869
296 AIR 0.4 0.828947
297 A G U 0.4 0.8
298 QQX 0.4 0.765432
299 NAJ 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3TII; Ligand: ANP; Similar sites found: 264
This union binding pocket(no: 1) in the query (biounit: 3tii.bio2) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4EN4 GT1 0.02054 0.41888 0.641026
2 4EN4 GT0 0.02054 0.41888 0.641026
3 4BFM ANP 0.0007042 0.4126 1.49701
4 3UDZ ADP 0.0005769 0.41412 1.57895
5 5JFS 6K0 0.01386 0.42877 1.62338
6 4L3L 5FI 0.000888 0.47877 1.64474
7 4LWA Q13 0.03833 0.40653 1.65289
8 1V0O INR 0.0007774 0.41713 1.73611
9 1E4E ADP 0.0004773 0.42709 1.74927
10 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.004962 0.4645 1.75439
11 2JDR L20 0.004962 0.4645 1.75439
12 4LRJ ANP 0.001795 0.41409 1.77515
13 5IH9 6BF 0.001981 0.46793 1.79104
14 3K5I ADP 0.000004056 0.4933 1.84211
15 4AZT LY2 0.003687 0.42147 1.84211
16 2HK5 1BM 0.00153 0.40084 1.85185
17 3LXN MI1 0.0007774 0.40868 1.88679
18 2VZ6 FEF 0.006235 0.40499 1.91693
19 1XJD STU 0.0004471 0.4252 2.02899
20 1M0W ANP 0.0000157 0.53853 2.10526
21 4OYA 1VE 0.03618 0.42243 2.10526
22 5TO8 7FM 0.007473 0.44167 2.12766
23 1Z2P I3S 0.000001382 0.40679 2.16049
24 1Z2P ACP 0.000001382 0.40679 2.16049
25 3SRV S19 0.002469 0.40875 2.16606
26 2Z7R STU 0.0004619 0.41286 2.18069
27 4F4P 0SB 0.02686 0.42636 2.1978
28 3FUR Z12 0.03367 0.41376 2.20588
29 5C1P DAL DAL 0.00009419 0.52044 2.28758
30 5C1P ADP 0.00004256 0.51502 2.28758
31 5GZ9 ANP 0.005326 0.43054 2.29508
32 5W2I ADP 0.000004477 0.58351 2.33463
33 5W2I I3P 0.000004477 0.58351 2.33463
34 5C03 AGS 0.003659 0.43094 2.33918
35 2YRX AMP 0.00004154 0.53139 2.36842
36 4UWH JXM 0.0005584 0.44403 2.36842
37 5AWM ANP 0.002066 0.43321 2.36842
38 4CLI 5P8 0.008281 0.44334 2.44648
39 4H3P ANP 0.001954 0.40791 2.48619
40 5BVE 4VG 0.001443 0.49645 2.49307
41 4YLL 4E3 0.001095 0.46422 2.49307
42 2YAB AMP 0.0008351 0.46391 2.49307
43 1IA9 ANP 0.000586 0.41948 2.5
44 2OFV 242 0.009623 0.43275 2.52708
45 2B9H ADP 0.0007227 0.46694 2.54958
46 2B9J ADP 0.001141 0.42491 2.54958
47 2B9F ADP 0.0009156 0.42355 2.54958
48 2B9I ADP 0.00132 0.41666 2.54958
49 5LI9 ACP 0.0009281 0.41294 2.57143
50 1U5R ATP 0.003198 0.40297 2.58621
51 5IQD GNP 0.004499 0.45085 2.62295
52 5IQD RIO 0.004731 0.45085 2.62295
53 4WNK 453 0.003077 0.45164 2.63158
54 3V8S 0HD 0.0009483 0.42415 2.63158
55 2WTX VDO 0.01921 0.41939 2.63158
56 2WTX UDP 0.02 0.41639 2.63158
57 3AHO 3A2 0.0257 0.40255 2.63158
58 3I0O ADP 0.0004338 0.46482 2.65487
59 4I94 ANP 0.003527 0.40074 2.66667
60 4BTK DTQ 0.001246 0.45336 2.67062
61 3HAV ATP 0.001665 0.45151 2.67559
62 5HCY 60D 0.009475 0.44027 2.71903
63 1KEW NAD 0.0406 0.41387 2.77008
64 2R7K AMZ 0.00003481 0.41238 2.77008
65 1ZN7 HSX 0.003699 0.42141 2.77778
66 1ZN7 ADE 0.003699 0.42141 2.77778
67 3G5D 1N1 0.003082 0.47479 2.7972
68 5U6C 7YS 0.005755 0.42717 2.85714
69 4Y8D 49J 0.001754 0.4098 2.85714
70 2PYW ADP 0.000004328 0.48745 2.89474
71 2QK4 ATP 0.0003077 0.46576 2.89474
72 3HZT J60 0.001581 0.43863 2.89474
73 1TZD ADP 0.000001255 0.60769 2.90909
74 4NFN 2KC 0.0006059 0.4339 2.91262
75 3MVH WFE 0.001174 0.47268 2.92398
76 2GU8 796 0.003014 0.4753 2.96736
77 4U44 3D9 0.001012 0.45771 3.01205
78 1W2D ADP 0.00001125 0.53875 3.01887
79 1W2D 4IP 0.00003945 0.41462 3.01887
80 4XV1 904 0.002876 0.45715 3.08219
81 3RE4 TO1 0.0007312 0.45425 3.10078
82 1ZTH ADP 0.001046 0.44699 3.10078
83 1ZP9 ATP 0.001139 0.43044 3.10078
84 2AQX ATP 0.0001157 0.43258 3.11419
85 1RE8 BD2 0.001523 0.48382 3.14286
86 4WB6 ATP 0.001655 0.46058 3.14286
87 4OCV ANP 0.0007516 0.41598 3.16623
88 1EHI ADP 0.0002814 0.43449 3.18302
89 1TQP ATP 0.00002571 0.43683 3.19149
90 5AIG VPR 0.01246 0.40098 3.2
91 4CQE CQE 0.002879 0.46196 3.23741
92 1BYG STU 0.004958 0.40305 3.23741
93 5AX9 4KT 0.001211 0.45397 3.24675
94 3NW7 LGV 0.02906 0.41636 3.25733
95 4UAP NGA 0.0035 0.43761 3.28947
96 2PVF ACP 0.004085 0.40015 3.29341
97 3GGF GVD 0.001997 0.42015 3.32226
98 1K3A ACP 0.0059 0.41439 3.34448
99 4N70 2HX 0.003695 0.46546 3.35366
100 3TKI S25 0.006184 0.45702 3.40557
101 2HY0 306 0.001778 0.4285 3.41615
102 3X01 AMP 0.00002057 0.54697 3.42105
103 4ME6 ADP 0.00005263 0.5252 3.42105
104 2F2U M77 0.003443 0.42286 3.42105
105 2F57 23D 0.004132 0.40494 3.47003
106 1GSA ADP 0.0000005419 0.50104 3.48101
107 5HVJ ANP 0.003146 0.43803 3.49206
108 3RI1 3RH 0.003318 0.44857 3.51438
109 1CM8 ANP 0.001001 0.42447 3.54223
110 4P5Z Q7M 0.01754 0.42143 3.60111
111 4G17 0VN 0.001673 0.44263 3.63636
112 5T8O 76Z 0.0006987 0.41073 3.68421
113 4WTV ATP 0.001777 0.4057 3.68421
114 3F5K CE5 0.02509 0.40437 3.68421
115 3KN5 ANP 0.003356 0.42592 3.69231
116 4AU8 Z3R 0.0008829 0.45043 3.71622
117 4JR7 GNP 0.0003015 0.48289 3.74332
118 5EOB 5QQ 0.04195 0.4131 3.76176
119 3E7O 35F 0.001039 0.47825 3.88889
120 4YZC STU 0.004382 0.45144 3.94737
121 2IO8 ADP 0.00003228 0.43893 3.94737
122 4Z3E GAL NGA GLA BGC GAL 0.007584 0.41951 4.0404
123 2Q7D ANP 0.000006919 0.44703 4.04624
124 3C8F MT2 0.002594 0.43109 4.08163
125 2IF8 ADP 0.000001548 0.59778 4.13223
126 4IJP 1EH 0.003018 0.43897 4.18994
127 4BHN BH9 0.0005061 0.41286 4.19162
128 4U98 ACP 0.00007618 0.46859 4.21053
129 4CYI ATP 0.001337 0.45612 4.21053
130 1T36 ADP 0.00006241 0.41619 4.21053
131 1NJJ GET 0.0149 0.40973 4.21053
132 4Y85 499 0.01449 0.40023 4.21687
133 4AUA 4AU 0.0004512 0.47209 4.23453
134 1IOW PHY 0.00001376 0.57665 4.24837
135 1IOW ADP 0.00001376 0.57665 4.24837
136 3GC0 AMP 0.001211 0.43606 4.25532
137 4Y0X ADP 0.0001322 0.49478 4.26667
138 4A4X JUP 0.002645 0.45046 4.30108
139 3PLS ANP 0.00189 0.41226 4.36242
140 4UX9 ANP 0.0004433 0.41695 4.3956
141 5UKL SIX 0.02096 0.40701 4.42478
142 5N87 N66 0.002564 0.46219 4.47284
143 3ORQ ADP 0.000003782 0.49635 4.50928
144 3ALN ANP 0.004414 0.41782 4.58716
145 5DXI TRE 0.009921 0.41012 4.63576
146 5MW8 ATP 0.0002492 0.49569 4.73684
147 4CRL C1I 0.001793 0.46758 4.73684
148 2PUL ACP 0.0001916 0.45286 4.73684
149 3KRR DQX 0.004803 0.46966 4.74576
150 5FBN 5WF 0.007195 0.43807 4.79705
151 4F9C 0SX 0.000298 0.44568 4.86111
152 5BYZ 4WE 0.01733 0.41502 4.88506
153 4O1P ANP 0.003515 0.40342 5
154 4OUC 5ID 0.01039 0.40503 5.04202
155 2GQR ADP 0.001283 0.42019 5.06329
156 3AQV TAK 0.002022 0.40906 5.07246
157 1Q8Y ADE 0.0041 0.42417 5.09383
158 1C1L GAL BGC 0.005911 0.4235 5.10949
159 4X7Q 3YR 0.0006334 0.42634 5.12821
160 4YZN 4K5 0.00229 0.44852 5.22648
161 4GYI ADP 0.00004665 0.49872 5.26316
162 4LH7 1X8 0.0004541 0.4808 5.26316
163 5I35 ANP 0.0001149 0.46225 5.26316
164 2YW2 ATP 0.00005844 0.45469 5.26316
165 2HGS ADP 0.00004717 0.44199 5.26316
166 3VPC ADP 0.00004134 0.45648 5.31915
167 5M06 ADP 0.003048 0.4303 5.43478
168 4UAL 3FV 0.0002176 0.48968 5.52632
169 5KO1 6UY 0.001704 0.41508 5.65371
170 3TXO 07U 0.0006683 0.44027 5.66572
171 2BKK ADP 0.005068 0.4175 5.68182
172 5JZJ AN2 0.004981 0.42241 5.72391
173 5UR1 YY9 0.0097 0.43879 5.78778
174 4NM5 ADP 0.03837 0.41303 5.83554
175 5UOX 8GY 0.0005974 0.40508 5.90406
176 4CFU 2WC 0.000953 0.43296 5.94059
177 4BCQ TJF 0.005255 0.41428 5.98007
178 4BCM T7Z 0.004272 0.40706 5.98007
179 2A19 ANP 0.002283 0.43119 5.98592
180 3OFM 4B0 0.000161 0.48789 6
181 4BCN T9N 0.0008708 0.4425 6
182 2XMY CDK 0.005165 0.46864 6.04027
183 5DXT 5H5 0.002678 0.43951 6.05263
184 5EKO N17 0.01742 0.40522 6.05263
185 3DAK ANP 0.003416 0.40935 6.2069
186 4FE2 ADP 0.002553 0.41943 6.27451
187 3F7Z 34O 0.0003088 0.48239 6.28571
188 1O9U ADZ 0.0007335 0.47877 6.28571
189 5JKG 6LF 0.01208 0.42983 6.43087
190 4O4F IHP 0.00003013 0.54692 6.45161
191 4O4F ATP 0.00002741 0.54692 6.45161
192 5UIU 8CG 0.00481 0.44188 6.50155
193 2V7O DRN 0.000394 0.47289 6.54762
194 4NST ADP 0.004012 0.42902 6.55271
195 3DLS ADP 0.0004854 0.46806 6.56716
196 1ZY5 ANP 0.001304 0.41954 6.60066
197 3PE2 E1B 0.0004731 0.51045 6.82493
198 3C0G 3AM 0.003237 0.41716 6.83761
199 3VOT ADP 0.00001254 0.53655 6.84211
200 5MJA 7O3 0.003235 0.42907 6.88525
201 4YMJ 4EJ 0.001633 0.45188 6.90789
202 5EFQ ADP 0.002698 0.43729 6.91643
203 1VJY 460 0.003383 0.45227 6.93069
204 2VN9 GVD 0.000547 0.46607 6.97674
205 5LXM ADP 0.005786 0.4193 7.06714
206 5MY8 RXZ 0.001461 0.4616 7.10526
207 5EW9 5VC 0.01013 0.4686 7.38007
208 4TWP AXI 0.004032 0.46066 7.38007
209 3ETH ATP 0.000006493 0.47483 7.60563
210 3V4S ATP 0.000001413 0.4999 7.63158
211 3V4S ADP 0.000004242 0.4102 7.63158
212 5W4W 9WG 0.003697 0.449 7.85498
213 4KBA 1QM 0.01181 0.40211 7.85498
214 2FB3 GTP 0.02123 0.40931 7.94118
215 2WEL K88 0.00133 0.45621 8
216 5TDF ADP 0.004633 0.42994 8.02469
217 4R78 AMP 0.003622 0.42675 8.09062
218 4D2S DYK 0.005892 0.41442 8.09859
219 5A6N U7E 0.00129 0.45481 8.12721
220 4IDT T28 0.001147 0.42172 8.14607
221 2PZI AXX 0.0002837 0.46323 8.1579
222 4XLI 1N1 0.001202 0.42189 8.20895
223 2ZV2 609 0.001211 0.44404 8.38926
224 1QB7 ADE 0.006494 0.40998 8.47458
225 3PN1 IVH 0.00496 0.40599 8.49057
226 1OBD ATP 0.003336 0.41638 8.49673
227 2VPQ ANP 0.000001231 0.48866 8.64745
228 4M69 ANP 0.005242 0.42733 8.68421
229 4BKJ STI 0.008235 0.42443 8.88889
230 5VC5 96M 0.001992 0.45816 8.99654
231 1UNH IXM 0.0001719 0.48655 9.13461
232 1NYW DAU 0.00422 0.42998 9.13706
233 4USF 6UI 0.009703 0.41935 9.21053
234 1MZV AMP 0.002097 0.43291 9.3617
235 3M2W L8I 0.001497 0.43206 9.36455
236 4WNP 3RJ 0.0004001 0.4578 9.40767
237 5HES 032 0.001148 0.46132 9.44625
238 4CFT M48 0.01693 0.40125 9.47368
239 5FI4 5XV 0.003338 0.44221 9.59752
240 2VQD AP2 0.00001253 0.47544 9.73684
241 5VZ0 ADP 0.0000005675 0.61015 10
242 5EYK 5U5 0.005797 0.43499 10.1695
243 3AKK ADP 0.0004218 0.4782 10.4615
244 5HQ0 LZ9 0.0007867 0.46728 10.596
245 3VPB ADP 0.00000452 0.4684 10.7143
246 2QF7 AGS 0.00006207 0.40964 11.0526
247 5X8I SQZ 0.0007175 0.42519 11.2717
248 4CC6 L5Y 0.008388 0.40925 11.3208
249 4ZS4 ATP 0.00118 0.40871 11.4007
250 4C2W ANP 0.003173 0.42452 11.5385
251 2X4Z X4Z 0.002242 0.46393 11.8243
252 4ZGP ADP 0.000386 0.47532 12.2867
253 3O0G 3O0 0.0005041 0.4698 12.7517
254 5DEY 59T 0.004361 0.4651 12.7946
255 4Q5H ANP 0.0002927 0.43864 13.1579
256 3H9R TAK 0.00689 0.41335 13.7615
257 4XYM A12 0.001067 0.45878 14.7826
258 5LVP ATP 0.002251 0.43408 15.7556
259 4MV1 ADP 0.00003449 0.55308 19.8718
260 4DC2 ADE 0.0002787 0.43622 21.4286
261 3VPD ANP 0.0000005193 0.51259 22.0641
262 5LI1 ANP 0.001722 0.45272 25
263 5L8L ADP 0.005731 0.41252 29.0598
264 3ZRM ZRM 0.0003342 0.43433 31.25
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