Receptor
PDB id Resolution Class Description Source Keywords
3TDV 2.2 Å NON-ENZYME: OTHER STRUCTURE OF THE GDP COMPLEX OF WILD-TYPE AMINOGLYCOSIDE 2'- PHOSPHOTRANSFERASE-IIIA ENTEROCOCCUS GALLINARUM KINASE PHOSPHORYL TRANSFER ANTIBIOTIC RESISTANCE GENTAMICTRANSFERASE
Ref.: AMINOGLYCOSIDE-2' PHOSPHOTRANSFERASE-IIIA (APH(2')-PREFERS GTP OVER ATP: STRUCTURAL TEMPLATES FOR NUCL RECOGNITION IN THE BACTERIAL AMINOGLYCOSIDE-2' KINA J.BIOL.CHEM. V. 287 12893 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:500;
B:500;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:501;
A:502;
A:503;
B:501;
B:502;
B:503;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3TDV 2.2 Å NON-ENZYME: OTHER STRUCTURE OF THE GDP COMPLEX OF WILD-TYPE AMINOGLYCOSIDE 2'- PHOSPHOTRANSFERASE-IIIA ENTEROCOCCUS GALLINARUM KINASE PHOSPHORYL TRANSFER ANTIBIOTIC RESISTANCE GENTAMICTRANSFERASE
Ref.: AMINOGLYCOSIDE-2' PHOSPHOTRANSFERASE-IIIA (APH(2')-PREFERS GTP OVER ATP: STRUCTURAL TEMPLATES FOR NUCL RECOGNITION IN THE BACTERIAL AMINOGLYCOSIDE-2' KINA J.BIOL.CHEM. V. 287 12893 2012
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 3TDW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3TDV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 3TDW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3TDV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 3TDW - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3TDV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3TDV; Ligand: GDP; Similar sites found: 331
This union binding pocket(no: 1) in the query (biounit: 3tdv.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4N14 WR7 0.01672 0.41331 1.30719
2 1Y57 MPZ 0.0005068 0.4599 1.63399
3 3G5D 1N1 0.001849 0.46838 1.74825
4 5UOX 8GY 0.000003297 0.55497 1.84502
5 1W2D ADP 0.008695 0.41288 1.88679
6 4GYI ADP 0.000007297 0.55251 1.96078
7 3FHR P4O 0.00004914 0.48707 1.96078
8 3BU5 ATP 0.0001569 0.47359 1.96078
9 4CLI 5P8 0.0009272 0.47346 1.96078
10 3C0G 3AM 0.0002576 0.44558 1.96078
11 1GSA ADP 0.00134 0.44104 1.96078
12 1H82 GZZ 0.01337 0.4316 1.96078
13 1H82 FAD 0.01145 0.4316 1.96078
14 5GZ9 ANP 0.0000009866 0.58088 1.96721
15 2XVD AS6 0.002738 0.43522 1.98676
16 5USZ SKE 0.0001147 0.49647 2.07612
17 1IA9 ANP 0.0001095 0.47154 2.14286
18 4OTH DRN 0.000001856 0.56604 2.28758
19 5HVJ ANP 0.0001021 0.52248 2.28758
20 4U44 3D9 0.00006373 0.49064 2.28758
21 4OH4 ANP 0.0001651 0.47262 2.28758
22 4Y85 499 0.0006962 0.44028 2.28758
23 5U6C 7YS 0.002068 0.43079 2.28758
24 4JK3 NAD 0.017 0.40011 2.3166
25 3VPC ADP 0.002477 0.4034 2.48227
26 3ORK AGS 0.000002804 0.5654 2.61438
27 4OCJ NDG 0.000008195 0.56451 2.61438
28 2PYW ADP 0.000009132 0.53281 2.61438
29 4ZS4 ATP 0.000008189 0.53225 2.61438
30 3NW7 LGV 0.0007827 0.4791 2.61438
31 2IF8 ADP 0.006982 0.4269 2.61438
32 1O9U ADZ 0.009173 0.41021 2.61438
33 1OLM VTQ 0.01036 0.40736 2.61438
34 1T36 ADP 0.01118 0.40583 2.61438
35 5FI4 5XV 0.008966 0.40575 2.61438
36 1K3A ACP 0.0003723 0.44195 2.67559
37 2OFV 242 0.003098 0.44069 2.88809
38 3PDT ADP 0.00001419 0.53201 2.90909
39 1XJD STU 0.000000522 0.58469 2.94118
40 2R5T ANP 0.0000003092 0.55733 2.94118
41 4BHN BH9 0.000002971 0.55433 2.94118
42 4JDI ANP 0.000006318 0.53987 2.94118
43 4M69 ANP 0.00001534 0.52288 2.94118
44 2JLD AG1 0.000003831 0.44686 2.94118
45 2F57 23D 0.0005422 0.44079 2.94118
46 3E7S AT2 0.0112 0.41692 2.94118
47 5FBN 5WF 0.00548 0.42789 2.95203
48 2HK5 1BM 0.007149 0.40506 2.96296
49 5HX8 66P 0.00002702 0.52308 2.98013
50 2X4Z X4Z 0.0003255 0.48512 3.04054
51 5LI1 ANP 0.00000000875 0.6693 3.26797
52 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.000005767 0.59249 3.26797
53 2JDR L20 0.000005767 0.59249 3.26797
54 5LI9 ACP 0.0000006955 0.56383 3.26797
55 4Y0X ADP 0.00006167 0.4819 3.26797
56 3ALN ANP 0.00005982 0.47455 3.26797
57 3UIM ANP 0.000418 0.45504 3.26797
58 2PZI AXX 0.002223 0.43645 3.26797
59 2Q7D ANP 0.003636 0.4266 3.26797
60 2VQD AP2 0.002349 0.42643 3.26797
61 3OND ADN 0.03837 0.40049 3.26797
62 5EW9 5VC 0.006429 0.46389 3.32103
63 5TO8 7FM 0.0004596 0.48336 3.5461
64 2Z7R STU 0.0000001852 0.56441 3.59477
65 4JR7 GNP 0.000001408 0.5628 3.59477
66 3I0O ADP 0.0002513 0.48668 3.59477
67 5VCV 1N1 0.0001793 0.48206 3.59477
68 3VOT ADP 0.0006632 0.42693 3.59477
69 1M0W ANP 0.001331 0.42394 3.59477
70 3KRL KRL 0.005033 0.41362 3.59477
71 2VPQ ANP 0.007706 0.40709 3.59477
72 5VZ0 ADP 0.005431 0.4021 3.59477
73 2FXU ATP 0.04976 0.40152 3.59477
74 3SXS PP2 0.00189 0.41448 3.73134
75 4KS7 X4Z 0.00002426 0.47602 3.76712
76 5VC5 96M 0.0006517 0.46212 3.80623
77 1OGX EQU 0.002144 0.41426 3.81679
78 3KMW ATP 0.004245 0.41497 3.87597
79 4WB6 ATP 0.00000003683 0.6529 3.92157
80 2QCS ANP 0.00000004287 0.64991 3.92157
81 2GU8 796 0.000001642 0.61817 3.92157
82 1RE8 BD2 0.000008101 0.57462 3.92157
83 4WB7 ATP 0.000004359 0.57417 3.92157
84 4OCV ANP 0.000003506 0.54841 3.92157
85 4L9I 8PR 0.00002873 0.49876 3.92157
86 4FL3 ANP 0.0000113 0.49829 3.92157
87 2PUL ACP 0.0002105 0.47316 3.92157
88 2H8H H8H 0.0009816 0.43888 3.92157
89 3WLV AZA 0.005691 0.43139 3.92157
90 3D91 REM 0.04498 0.4289 3.92157
91 3SLS ANP 0.0000762 0.46331 3.94737
92 2XMY CDK 0.00003572 0.56015 4.02685
93 1UNH IXM 0.0006396 0.43244 4.10959
94 4WNK 453 0.0000004004 0.61275 4.24837
95 5EOB 5QQ 0.0001415 0.52221 4.24837
96 3GNI ATP 0.00001481 0.50122 4.24837
97 3WO0 ALA 0.001132 0.46365 4.24837
98 5JFS 6K0 0.001388 0.4618 4.24837
99 1OPK P16 0.01077 0.41055 4.24837
100 3B20 NAD 0.01253 0.4007 4.24837
101 5DEY 59T 0.0002123 0.51262 4.3771
102 4XV1 904 0.000532 0.47379 4.45205
103 3G08 FEE 0.04429 0.40023 4.5614
104 3OFM 4B0 0.00007249 0.46956 4.57143
105 5UIU 8CG 0.000008583 0.55164 4.57516
106 2X2M X2M 0.00005515 0.50067 4.57516
107 3X01 AMP 0.001056 0.4703 4.57516
108 4YMJ 4EJ 0.0004829 0.48951 4.60526
109 4CQE CQE 0.00122 0.41546 4.67626
110 4AT3 LTI 0.009541 0.4117 4.68227
111 4TWP AXI 0.0006498 0.48194 4.79705
112 3DAK ANP 0.0005679 0.45891 4.82759
113 1U59 STU 0.000003435 0.54591 4.87805
114 4AXD ANP 0.0000003173 0.63104 4.90196
115 3UDZ ADP 0.0000001464 0.6089 4.90196
116 5MY8 RXZ 0.000006049 0.55035 4.90196
117 4K33 ACP 0.00000498 0.54173 4.90196
118 4P5Z Q7M 0.002262 0.44947 4.90196
119 3AKK ADP 0.001156 0.43795 4.90196
120 1ZY5 ANP 0.0008111 0.43693 4.9505
121 5CEO 50D 0.0002925 0.4618 5
122 3IGO ANP 0.0000009494 0.53764 5.22876
123 2V7O DRN 0.0000008024 0.52627 5.22876
124 2PVF ACP 0.00002164 0.50485 5.22876
125 5UR1 YY9 0.0003288 0.49386 5.22876
126 5DH3 5BS 0.0001606 0.47787 5.22876
127 4F4P 0SB 0.007374 0.44108 5.22876
128 5AWM ANP 0.002245 0.40765 5.22876
129 4CRL C1I 0.0003789 0.48063 5.26316
130 3GQI ACP 0.000007175 0.53197 5.30973
131 4I94 ANP 0.0006018 0.44399 5.33333
132 4G31 0WH 0.005993 0.42487 5.35117
133 3O0G 3O0 0.0002315 0.46101 5.36913
134 3PVW QRX 0.000008705 0.4697 5.40541
135 4YZC STU 0.000002069 0.59102 5.55556
136 3TKI S25 0.00001193 0.5737 5.55556
137 4X7Q 3YR 0.000003339 0.54645 5.55556
138 2B9J ADP 0.000009097 0.53397 5.55556
139 2B9I ADP 0.00001179 0.52257 5.55556
140 5I35 ANP 0.00001124 0.51625 5.55556
141 2B9F ADP 0.00001822 0.51433 5.55556
142 2B9H ADP 0.00002345 0.51221 5.55556
143 5JGA 6KC 0.0001941 0.49262 5.55556
144 2WU6 DKI 0.000009321 0.48676 5.55556
145 3EKK GS2 0.0004577 0.4809 5.55556
146 5C03 AGS 0.0002235 0.46689 5.55556
147 2HY0 306 0.0008786 0.4553 5.55556
148 4WOV 3SM 0.000402 0.43978 5.55556
149 3E8N ATP 0.0000136 0.56252 5.57185
150 3E8N VRA 0.03454 0.42378 5.57185
151 2WEI VGG 0.004457 0.40037 5.57491
152 3IDB ANP 0.000008397 0.53937 5.59006
153 2VN9 GVD 0.00001826 0.47705 5.64784
154 2Y88 2ER 0.01967 0.40401 5.7377
155 4AU8 Z3R 0.002507 0.43881 5.74324
156 2VZ6 FEF 0.00004853 0.51407 5.7508
157 3SRV S19 0.0000102 0.51876 5.77617
158 5DMZ ADP 0.000000005275 0.66852 5.88235
159 4F9C 0SX 0.0000001467 0.59582 5.88235
160 5HCY 60D 0.0003617 0.49303 5.88235
161 5JKG 6LF 0.000685 0.47394 5.88235
162 4FE2 ADP 0.0005591 0.46447 5.88235
163 1CM8 ANP 0.0006003 0.44245 5.88235
164 5HES 032 0.002984 0.42372 5.88235
165 3PP0 03Q 0.0005281 0.40985 5.88235
166 4YZN 4K5 0.000001834 0.56886 5.92335
167 4EWH T77 0.00002789 0.44654 6.18182
168 3QCQ 3Q0 0.00000541 0.61553 6.20915
169 4FG8 ATP 0.000001072 0.57386 6.20915
170 3MVH WFE 0.000004965 0.56255 6.20915
171 5LVP ATP 0.000002161 0.52899 6.20915
172 3SXF BK5 0.00005546 0.52097 6.20915
173 2XK9 XK9 0.0001393 0.50377 6.20915
174 4AZT LY2 0.0001052 0.46013 6.20915
175 3ETH ATP 0.005698 0.41123 6.20915
176 1VJY 460 0.00002176 0.53661 6.27063
177 2GQR ADP 0.0001198 0.47223 6.32911
178 2GQS ADP 0.0001547 0.46783 6.32911
179 3M2W L8I 0.0000004271 0.55425 6.35452
180 1TQP ATP 0.00002409 0.46718 6.38298
181 5UKL SIX 0.000003665 0.56453 6.45161
182 4QMN DB8 0.00007243 0.51706 6.45161
183 2H7C COA 0.02952 0.41174 6.45756
184 5M06 ADP 0.0001591 0.46204 6.52174
185 2WQN ADP 0.000005102 0.55978 6.53595
186 4UAL 3FV 0.000002768 0.55 6.53595
187 1OUK 084 0.0002221 0.54031 6.53595
188 4BTK DTQ 0.000008572 0.52861 6.53595
189 4EUU BX7 0.00002561 0.52414 6.53595
190 4OUC 5ID 0.000006347 0.51929 6.53595
191 4NFN 2KC 0.00002541 0.51409 6.53595
192 3HZT J60 0.00003524 0.47112 6.53595
193 2HGS ADP 0.0009498 0.44772 6.53595
194 4LOO SB4 0.002143 0.42409 6.53595
195 4ASE AV9 0.006896 0.41543 6.53595
196 3ZJX BOG 0.00071 0.48089 6.57439
197 4WNP 3RJ 0.00000976 0.50204 6.62021
198 3GGF GVD 0.00001638 0.52916 6.64452
199 3PLS ANP 0.00004897 0.48873 6.71141
200 5JZJ AN2 0.0000001355 0.59755 6.73401
201 4IDT T28 0.000004136 0.54923 6.86275
202 2F2U M77 0.00002415 0.5354 6.86275
203 3TXO 07U 0.000003829 0.52699 6.86275
204 4IJP 1EH 0.00004839 0.50086 6.86275
205 3V8S 0HD 0.00003261 0.49672 6.86275
206 3RI1 3RH 0.0001368 0.49117 6.86275
207 3K5I ADP 0.003645 0.40454 6.86275
208 3GC8 B45 0.002726 0.40002 6.86275
209 5DRB 5FJ 0.0001233 0.51772 6.87285
210 4L3L 5FI 0.0001002 0.50265 6.90789
211 1Q8Y ADP 0.00000007808 0.62406 7.18954
212 5X8I SQZ 0.000001285 0.56453 7.18954
213 1Q8Y ADE 0.00006752 0.4539 7.18954
214 5T8O 76Z 0.0006111 0.43456 7.18954
215 4XYM A12 0.002409 0.42396 7.3913
216 5LJB RTL 0.004601 0.41353 7.40741
217 3VPD ANP 0.005051 0.41356 7.47331
218 5N87 N66 0.0001133 0.50796 7.51634
219 5IH9 6BF 0.000273 0.49008 7.51634
220 4NW6 2NS 0.000002227 0.45767 7.51634
221 4Y93 746 0.001341 0.44458 7.51634
222 3HMO STU 0.001583 0.4341 7.51634
223 3GC0 AMP 0.001296 0.41952 7.51634
224 4A4X JUP 0.0003206 0.47441 7.52688
225 5L8L ADP 0.00006867 0.46596 7.7193
226 5LXM ADP 0.000001683 0.55202 7.77385
227 1OBD ATP 0.0001945 0.45053 7.84314
228 4R78 AMP 0.0005216 0.43213 7.84314
229 3V4S ATP 0.007398 0.40618 7.84314
230 3V4S ADP 0.01742 0.40545 7.84314
231 4R38 RBF 0.008937 0.40076 7.85714
232 5DA3 58V 0.01172 0.40664 7.92453
233 1PHK ATP 0.000001142 0.56977 8.05369
234 4BFM ANP 0.00000005479 0.63086 8.16993
235 4UX9 ANP 0.0000009447 0.54834 8.16993
236 4IZY 1J2 0.000002111 0.53127 8.16993
237 4ANW O92 0.0003177 0.48272 8.16993
238 4OAV ACP 0.0001641 0.46725 8.16993
239 3TTI KBI 0.00001592 0.45834 8.16993
240 4OYA 1VE 0.005173 0.45227 8.16993
241 4WHZ 3NL 0.006116 0.43789 8.16993
242 4U98 ACP 0.001473 0.43549 8.16993
243 3PTG 932 0.0005227 0.42475 8.16993
244 5W2I I3P 0.00495 0.41736 8.17121
245 5W2I ADP 0.00495 0.41736 8.17121
246 3E5A VX6 0.0006274 0.41098 8.20895
247 2Y6O 1N1 0.008067 0.4045 8.24742
248 4LRJ ANP 0.00000001826 0.63504 8.28402
249 5HQ0 LZ9 0.000002515 0.55752 8.33333
250 5HWV MBN 0.0007768 0.40448 8.46154
251 5MW8 ATP 0.00000003376 0.64629 8.49673
252 5BVE 4VG 0.000003799 0.60569 8.82353
253 4QTB 38Z 0.000005155 0.55983 8.82353
254 4H3Q ANP 0.000009461 0.53706 8.82353
255 3F7Z 34O 0.00001485 0.5182 8.82353
256 4H3P ANP 0.0000643 0.49047 8.82353
257 3ZRM ZRM 0.0004103 0.45539 8.82353
258 5TDF ADP 0.001319 0.43751 8.82353
259 4YRY NAD 0.02237 0.41127 8.82353
260 4NM5 ADP 0.02707 0.40798 8.82353
261 3Q60 ATP 0.00006094 0.48456 9.15033
262 3E7O 35F 0.009362 0.41462 9.15033
263 3KRR DQX 0.0001488 0.52839 9.15254
264 2AQX ATP 0.008884 0.40263 9.34256
265 2BKK ADP 0.000004913 0.51521 9.4697
266 3DLS ADP 0.000005011 0.5232 9.47712
267 5BYZ 4WE 0.0004429 0.47454 9.47712
268 3TM0 ANP 0.00007248 0.41379 9.5057
269 3TM0 B31 0.0000784 0.40829 9.5057
270 2A19 ANP 0.00001971 0.53962 9.50704
271 3AQV TAK 0.003308 0.41586 9.78261
272 3KN5 ANP 0.00009178 0.46742 9.80392
273 4O1P ANP 0.0002606 0.46398 9.80392
274 4UWH JXM 0.0007264 0.45403 10.1307
275 4C2V YJA 0.00003943 0.52123 10.1754
276 4C2W ANP 0.0001473 0.45222 10.3943
277 3LXN MI1 0.0000006179 0.58442 10.4575
278 1U5R ATP 0.00004243 0.49231 10.4575
279 5W4W 9WG 0.0003865 0.47727 10.4575
280 5TA6 79D 0.001175 0.45047 10.4575
281 3FC2 IBI 0.03589 0.41113 10.4575
282 4KBA 1QM 0.0108 0.40047 10.4575
283 5EYK 5U5 0.0003278 0.47571 10.5072
284 4CFU 2WC 0.00003752 0.51274 10.8911
285 4GJ3 0XP 0.000004918 0.56465 10.9272
286 4BCM T7Z 0.00006762 0.48376 10.9635
287 4BCQ TJF 0.000916 0.4224 10.9635
288 4E1Z 0MX 0.000009217 0.53757 10.9966
289 4BCN T9N 0.00005764 0.51058 11
290 2RIO ADP 0.000005447 0.53217 11.1111
291 1ZP9 ATP 0.0000393 0.48645 11.2403
292 1ZTH ADP 0.0000232 0.48006 11.2403
293 1EPB REA 0.007599 0.40367 11.5854
294 2Y69 CHD 0.004371 0.43686 11.6279
295 2YAB AMP 0.00000001973 0.64707 11.7647
296 4NST ADP 0.00004877 0.4957 11.7647
297 1IOW ADP 0.005721 0.42702 11.7647
298 1IOW PHY 0.005721 0.42702 11.7647
299 3RE4 TO1 0.0002527 0.44139 12.0155
300 4I6H 1C8 0.003891 0.41279 12.0915
301 3FHI ANP 0.00000007851 0.63801 12.3377
302 4N70 2HX 0.000003823 0.59293 12.4183
303 3CY2 MB9 0.00000178 0.56943 12.4183
304 5EFQ ADP 0.0001006 0.482 12.4183
305 2PVN P63 0.0000005386 0.49456 12.7451
306 5LMK 6ZK 0.003182 0.40998 12.7946
307 3PE2 E1B 0.000004823 0.58546 13.0719
308 4G17 0VN 0.001575 0.42159 13.0719
309 2YAK OSV 0.00000319 0.57138 13.3333
310 5A6N U7E 0.000000498 0.58558 13.4276
311 4YLL 4E3 0.00001446 0.52884 13.7255
312 4Q5H ANP 0.0000000507 0.6257 14.4737
313 1V0O INR 0.00002282 0.50057 14.9306
314 5AX9 4KT 0.0000509 0.49489 15.0327
315 3LXK MI1 0.000008768 0.46282 15.5963
316 2CSN CKI 0.0000001581 0.62424 16.1616
317 3VPB ADP 0.000701 0.40925 17.8571
318 5G1X ADP 0.00000656 0.52711 19.0476
319 2ZV2 609 0.00002447 0.53513 19.4631
320 1BYG STU 0.00003041 0.4925 20.1439
321 4Y8D 49J 0.001936 0.42602 20.5882
322 4AUA 4AU 0.0001254 0.47261 22.8013
323 5IH1 GDP 0.00000449 0.59204 28.8079
324 5IH1 6BQ 0.00000449 0.59204 28.8079
325 3W0O HY0 0.00003429 0.52402 36.9281
326 3W0O ADP 0.00003429 0.52402 36.9281
327 5IGI GMP 0.00003296 0.53457 39.8671
328 5IGI ZIT 0.00003541 0.53457 39.8671
329 5IQD RIO 0.00000005741 0.66603 42.9508
330 5IQD GNP 0.0000000523 0.66603 42.9508
331 3HAV ATP 0.00009106 0.43046 45.1505
Pocket No.: 2; Query (leader) PDB : 3TDV; Ligand: GDP; Similar sites found: 8
This union binding pocket(no: 2) in the query (biounit: 3tdv.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2IVD ACJ 0.01219 0.40182 2.61438
2 2CWH NDP 0.01568 0.40174 2.94118
3 2XG5 EC5 0.01759 0.401 3.46821
4 2XG5 EC2 0.01759 0.401 3.46821
5 4C3Y ANB 0.03485 0.40179 3.92157
6 4USF 6UI 0.01161 0.40069 4.27632
7 1DZK PRZ 0.004454 0.41807 5.73248
8 2V2V V12 0.03006 0.40086 10.3321
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