Receptor
PDB id Resolution Class Description Source Keywords
3T7S 2.2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF COMPLEX OF SAM AND BVU_3255, A METHYLTR FROM BACTEROIDES VULGATUS ATCC 8482 BACTEROIDES VULGATUS SMALL MOLECULE METHYLTRANSFERASE BVU_3255 ROSSMANN FOLD METHYLTRASNFERASE SAM METHYLATION TRANSFERASE
Ref.: STRUCTURAL CHARACTERIZATION OF BVU_3255, A METHYLTR FROM HUMAN INTESTINE ANTIBIOTIC RESISTANT PATHOGEN BACTEROIDES VULGATUS J.STRUCT.BIOL. 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:300;
B:300;
C:300;
D:300;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Ka = 44500 M^-1
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3T7S 2.2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF COMPLEX OF SAM AND BVU_3255, A METHYLTR FROM BACTEROIDES VULGATUS ATCC 8482 BACTEROIDES VULGATUS SMALL MOLECULE METHYLTRANSFERASE BVU_3255 ROSSMANN FOLD METHYLTRASNFERASE SAM METHYLATION TRANSFERASE
Ref.: STRUCTURAL CHARACTERIZATION OF BVU_3255, A METHYLTR FROM HUMAN INTESTINE ANTIBIOTIC RESISTANT PATHOGEN BACTEROIDES VULGATUS J.STRUCT.BIOL. 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 3T7S Ka = 44500 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
2 3T7T Ka = 29900 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 3T7S Ka = 44500 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
2 3T7T Ka = 29900 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 3T7S Ka = 44500 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
2 3T7T Ka = 29900 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found: 320
This union binding pocket(no: 1) in the query (biounit: 3t7s.bio2) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BOS GLA GAL GLC 0.01775 0.40485 None
2 1GYY FHC 0.01817 0.40386 None
3 1V6A TRE 0.01837 0.40779 1.1194
4 5EZ7 FAD 0.0236 0.40121 1.49254
5 1H8P PC 0.02897 0.41251 1.83486
6 3A25 SAM 0.000157 0.47099 1.86567
7 3ICR FAD 0.0129 0.41157 1.86567
8 3WCZ CIT 0.0242 0.40833 1.86567
9 5FTW SAH 0.00002232 0.48915 1.95312
10 1U2Z SAH 0.0000158 0.52343 2.23881
11 4UCI SAM 0.0001259 0.47743 2.23881
12 1YXM ADE 0.0009305 0.46624 2.23881
13 5G3U FDA 0.002593 0.44507 2.23881
14 1MO9 KPC 0.01581 0.43383 2.23881
15 3CGD COA 0.01533 0.43348 2.23881
16 3CGD FAD 0.01533 0.43348 2.23881
17 1MO9 FAD 0.01941 0.4288 2.23881
18 2JHF NAD 0.04218 0.42712 2.23881
19 5U8U FAD 0.01704 0.42507 2.23881
20 1KYQ NAD 0.006273 0.4057 2.23881
21 5A3B APR 0.000801 0.4038 2.23881
22 2ZWI C5P 0.01592 0.40208 2.23881
23 4OBW SAM 0.00001239 0.51832 2.33463
24 3FRH SAH 0.00001712 0.5219 2.37154
25 1UAY ADN 0.00007664 0.5011 2.47934
26 1V59 NAD 0.0005145 0.46843 2.61194
27 1JQD HSM 0.00001071 0.46087 2.61194
28 1JQD SAH 0.000003854 0.45844 2.61194
29 4RDH AMP 0.000632 0.45413 2.61194
30 4YAG NAI 0.003137 0.44532 2.61194
31 4RDI ATP 0.0007971 0.4407 2.61194
32 4D79 ATP 0.0008592 0.4393 2.61194
33 4FC7 COA 0.004812 0.43657 2.61194
34 5LAU AR6 0.002004 0.43274 2.61194
35 1P77 ATR 0.006708 0.42974 2.61194
36 4YNU FAD 0.008285 0.42723 2.61194
37 4YNU LGC 0.01006 0.42656 2.61194
38 2Q28 ADP 0.001239 0.42652 2.61194
39 5JCA FAD 0.01637 0.41144 2.61194
40 5JCA NDP 0.03116 0.41024 2.61194
41 3BGD SAH 0.000004132 0.50037 2.69231
42 3BGD PM6 0.000007872 0.46171 2.69231
43 3GEG NAD 0.00004403 0.43426 2.83401
44 1X87 NAD 0.0005922 0.42079 2.90381
45 3ML1 MGD 0.01252 0.43465 2.96296
46 2AOT SAH 0.000001226 0.57578 2.98507
47 4ONQ SFG 0.000007807 0.52693 2.98507
48 5JJR SAH 0.00001356 0.51664 2.98507
49 2JJQ SAH 0.00004578 0.51137 2.98507
50 2WA2 SAM 0.00005952 0.49447 2.98507
51 2ZWA SAH 0.00001834 0.48625 2.98507
52 4M37 SAH 0.00004808 0.48421 2.98507
53 2EJU SAH 0.0001908 0.46736 2.98507
54 1PN0 IPH 0.008624 0.42978 2.98507
55 1PN0 FAD 0.008292 0.42978 2.98507
56 1Y8Q ATP 0.0003101 0.42673 2.98507
57 3GGO ENO 0.01386 0.41396 2.98507
58 5CUQ NSC 0.00001068 0.54653 2.99625
59 2BZG SAH 0.000003793 0.54038 3.01724
60 1G1T SIA GAL MAG FUC 0.02657 0.40262 3.18471
61 1WG8 SAM 0.00002074 0.52039 3.35821
62 3GCZ SAM 0.00002165 0.50791 3.35821
63 1R6D DAU 0.002142 0.46132 3.35821
64 1R6D NAD 0.00225 0.4611 3.35821
65 5L95 AMP 0.0003383 0.4589 3.35821
66 1ZQ9 SAM 0.0007869 0.44094 3.35821
67 5EB4 FAD 0.004699 0.4351 3.35821
68 3H8V ATP 0.001371 0.43059 3.35821
69 4EIP K2C 0.008005 0.42967 3.35821
70 4EIP FAD 0.008005 0.42967 3.35821
71 3M6W SAM 0.008507 0.40341 3.35821
72 1G60 SAM 0.00002035 0.49924 3.46154
73 3G2O SAM 0.000000252 0.59091 3.73134
74 3VSE SAH 0.0000365 0.52245 3.73134
75 5JAQ NAI 0.002163 0.44982 3.73134
76 3VYW SAM 0.0004645 0.43901 3.73134
77 3C6K MTA 0.003817 0.43506 3.73134
78 3TKA SAM 0.0007617 0.42854 3.73134
79 1BZL FAD 0.02799 0.42657 3.73134
80 4PIO AVI 0.00001518 0.42326 3.73134
81 4PIO SAH 0.00001618 0.4174 3.73134
82 2JHP SAH 0.005654 0.40768 3.73134
83 3RKR NAP 0.003392 0.43456 3.81679
84 2AE2 PTO 0.004189 0.43744 3.84615
85 2AE2 NAP 0.004189 0.43744 3.84615
86 4POO SAM 0.0001656 0.43598 4
87 2UYQ SAM 0.00002393 0.56004 4.10448
88 3GWZ SAH 0.000006589 0.55001 4.10448
89 3GXO SAH 0.00001345 0.52913 4.10448
90 3EVG SAH 0.00001849 0.51086 4.10448
91 2P41 SAH 0.00002779 0.50326 4.10448
92 3FUU ADN 0.0001745 0.46246 4.10448
93 4RPL 3UC 0.005741 0.44972 4.10448
94 4RPL FAD 0.00577 0.4477 4.10448
95 5XLX SAH 0.0007973 0.4407 4.10448
96 3U31 NAD 0.0005312 0.42848 4.10448
97 5FJN FAD 0.007575 0.42727 4.10448
98 5FJN BE2 0.008627 0.42727 4.10448
99 2HK9 ATR 0.005202 0.42559 4.10448
100 1LVL NAD 0.0009772 0.42397 4.10448
101 3L9W AMP 0.00008367 0.41642 4.10448
102 3L9W GSH 0.0002166 0.41286 4.10448
103 5XDT MB3 0.01043 0.41152 4.10448
104 2QQF A1R 0.007735 0.4083 4.10448
105 1E1M FAD 0.03373 0.40404 4.10448
106 5XDT GDP 0.0112 0.40255 4.10448
107 5GT9 NAP 0.003169 0.43269 4.18251
108 2E0N SAH 0.004493 0.41207 4.2471
109 4IF4 BEF 0.005769 0.43562 4.32692
110 5HJM MTA 0.000006784 0.51895 4.47761
111 3QOX SAH 0.000001257 0.5181 4.47761
112 1UWK NAD 0.0007152 0.47864 4.47761
113 3DUW SAH 0.0002574 0.45556 4.47761
114 4N9Z V3L 0.001801 0.44356 4.47761
115 2VT3 ATP 0.002215 0.43862 4.47761
116 4BV6 FAD 0.007463 0.42663 4.47761
117 5JCM NAD 0.02278 0.4188 4.47761
118 5JCM FAD 0.02477 0.4164 4.47761
119 5JCM ISD 0.02546 0.4164 4.47761
120 1LCF OXL 0.02446 0.40031 4.47761
121 1Q0S SAH 0.00008812 0.44453 4.6332
122 3FGZ BEF 0.009418 0.41431 4.6875
123 5BXV MGP 0.03505 0.40304 4.6875
124 4ZA2 NAD 0.005004 0.42103 4.74308
125 3PT9 SAH 0.000006273 0.531 4.85075
126 1RJD SAM 0.00001197 0.50093 4.85075
127 3NDJ JHZ 0.0004995 0.48704 4.85075
128 1NW5 SAM 0.0002027 0.4577 4.85075
129 4OPC FDA 0.01022 0.44961 4.85075
130 3S1S SAH 0.0001377 0.44541 4.85075
131 3ZNN FAD 0.01831 0.41908 4.85075
132 5BUK FAD 0.01257 0.41862 4.85075
133 5MBX SP5 0.01842 0.41759 4.85075
134 5MBX FAD 0.01842 0.41759 4.85075
135 4USR FAD 0.00788 0.41711 4.85075
136 1PL6 NAD 0.00332 0.40337 4.85075
137 4MO2 FDA 0.005675 0.42817 4.8913
138 5ITV NAI 0.000907 0.45734 5.09804
139 5X62 SAH 0.0000005659 0.58315 5.22388
140 2PX8 SAH 0.0003287 0.45722 5.22388
141 1V5F FAD 0.004511 0.45297 5.22388
142 5J60 FAD 0.005779 0.43089 5.22388
143 2V3V MGD 0.01627 0.42952 5.22388
144 1P31 EPU 0.004529 0.40829 5.22388
145 1SQL GUN 0.01161 0.41958 5.47945
146 2EG5 SAH 0.000001381 0.58115 5.59701
147 5XVK SAH 0.000004872 0.49903 5.59701
148 4DMG SAM 0.0001375 0.49538 5.59701
149 3GRU AMP 0.00004484 0.46514 5.59701
150 1BC5 SAH 0.000149 0.44239 5.59701
151 4J1Q NDP 0.002398 0.43397 5.59701
152 1NVM NAD 0.006461 0.42107 5.59701
153 1TZD ADP 0.008709 0.43159 5.97015
154 1G8K MGD 0.007508 0.44456 6.01504
155 5T2U NAP 0.01176 0.40913 6.04839
156 1Z5U CMP 0.006396 0.43079 6.07477
157 3O7W SAM 0.0000007058 0.59453 6.12245
158 2FKA BEF 0.004662 0.43886 6.20155
159 2QX0 PH2 0.008505 0.43176 6.28931
160 4N49 SAM 0.00002782 0.48583 6.34328
161 4X9M FAD 0.005953 0.43028 6.34328
162 5GWX SAR 0.0002678 0.42285 6.34328
163 5GWX SAM 0.0002678 0.42285 6.34328
164 2H7C SIA 0.007525 0.41542 6.34328
165 5DM1 SAH 0.000001959 0.42298 6.36704
166 5DM1 5D7 0.000002113 0.41778 6.36704
167 2VDV SAM 0.00000005229 0.64641 6.50407
168 2XYQ SAH 0.004161 0.40987 6.55738
169 2HYQ MAN MAN 0.0263 0.40137 6.55738
170 5KXE 6Y2 0.02092 0.40486 6.58436
171 4DCM SAM 0.0003515 0.46556 6.71642
172 1G0N PHH 0.005502 0.43287 6.71642
173 1G0N NDP 0.005169 0.43111 6.71642
174 1N2X SAM 0.00002897 0.46756 7.08955
175 4D7E FAD 0.003005 0.43986 7.08955
176 3P9C SAH 0.00009725 0.40564 7.08955
177 2FAV APR 0.01096 0.40156 7.22222
178 3G89 SAM 0.00000001722 0.66855 7.22892
179 5O4J PJL 0.004297 0.42918 7.29927
180 5O4J 9KH 0.00487 0.42788 7.29927
181 5O4J SAH 0.00487 0.42788 7.29927
182 3DXY SAM 0.00003503 0.52328 7.33945
183 5MW4 5JU 0.000008836 0.56261 7.46269
184 2A14 SAH 0.00001154 0.49413 7.46269
185 1KYZ SAH 0.00006963 0.48614 7.46269
186 3RIY NAD 0.00183 0.44213 7.46269
187 2NYR SVR 0.04192 0.41269 7.46269
188 2R4J 13P 0.02523 0.40951 7.46269
189 1KYZ FER 0.0003906 0.4077 7.46269
190 2AF6 BRU 0.02316 0.40409 7.46269
191 3I53 SAH 0.0000008632 0.54365 7.83133
192 4A6D SAM 0.00001183 0.50927 7.83582
193 3X0D SAH 0.00009695 0.47193 7.83582
194 4REP FAD 0.004302 0.43587 7.83582
195 2PXX SAH 0.0000001151 0.59126 7.90698
196 4BLW SAH 0.0005828 0.40554 7.95848
197 3GU3 SAH 0.0000001342 0.64668 8.09859
198 3TKY SAH 0.000003163 0.54653 8.20895
199 3A4T SFG 0.000015 0.48892 8.20895
200 3LXD FAD 0.004867 0.42905 8.20895
201 1WY7 SAH 0.0002335 0.44225 8.21256
202 4J4H NAI 0.0428 0.43137 8.49421
203 4J4H 1J1 0.009597 0.42591 8.49421
204 4YSX FAD 0.002746 0.44603 8.51064
205 5E9W SAH 0.0000005218 0.54356 8.58209
206 3OND ADN 0.007235 0.43261 8.58209
207 4D42 W0I 0.02267 0.41032 8.58209
208 4D42 NAP 0.02267 0.41032 8.58209
209 2BZ1 TAU 0.005881 0.41827 8.67347
210 2EUG URA 0.02454 0.4042 8.73362
211 2HMT NAI 0.0004819 0.4305 9.02778
212 5J6Y GLC 0.005818 0.44259 9.04255
213 5J6Y BGC 0.005818 0.44259 9.04255
214 3LCC SAH 0.00000003324 0.63714 9.32836
215 5THQ NDP 0.005384 0.42093 9.32836
216 4ORM FMN 0.0376 0.40676 9.32836
217 4ORM 2V6 0.0376 0.40676 9.32836
218 4JN6 OXL 0.02042 0.40292 9.32836
219 1QAN SAH 0.00001355 0.48982 9.42623
220 3SSO SAH 0.0004408 0.43796 9.70149
221 3NJ4 AFX 0.03117 0.43021 9.70149
222 1Q9I TEO 0.01187 0.4283 9.70149
223 5UAO FAD 0.006315 0.42706 9.70149
224 4J7U NAP 0.01046 0.42065 9.70149
225 4J7U YTZ 0.01046 0.42065 9.70149
226 1XDS SAM 0.000001264 0.58292 9.89305
227 3R51 MMA 0.01535 0.40141 10
228 3U4C NDP 0.0003029 0.40494 10.0746
229 3C3Y SAH 0.002757 0.41272 10.1266
230 3Q87 SAM 0.0008099 0.41479 10.4
231 3D3W NAP 0.003648 0.43244 10.6557
232 3GDH SAH 0.000001449 0.50842 10.7884
233 2IZ1 ATR 0.005358 0.43717 10.8209
234 3WV8 ATP 0.004901 0.40872 11.0092
235 2ZIF SAM 0.00001091 0.51057 11.194
236 4C4A SAH 0.00003155 0.49184 11.194
237 3JWH SAH 0.00000004491 0.65922 11.5207
238 1G55 SAH 0.000004874 0.52571 11.5672
239 3CH6 NAP 0.002382 0.46522 11.5672
240 1P1C SAH 0.000218 0.44022 11.5672
241 1XCL SAH 0.0002447 0.40112 11.5672
242 1NV8 MEQ 0.00002561 0.44131 11.6197
243 1NV8 SAM 0.00002813 0.43396 11.6197
244 5N53 8NB 0.01025 0.42298 11.7949
245 2DPM SAM 0.00005121 0.4672 11.9718
246 4CVN ADP 0.02433 0.40115 12.4088
247 3EGI ADP 0.000008193 0.57767 12.6214
248 2PZM UDP 0.0009277 0.47127 12.6866
249 1L1E SAH 0.00000008078 0.58588 13.2404
250 2NXE SAM 0.000002931 0.54518 13.3858
251 3EGV SAH 0.00002483 0.51112 13.3858
252 4M73 SAH 0.0000003733 0.62024 13.4328
253 2FK8 SAM 0.0000002041 0.57007 13.4328
254 4M73 M72 0.0000005441 0.44467 13.4328
255 1QZZ SAM 0.000002555 0.56889 13.806
256 1ZMD NAI 0.0009191 0.40485 13.806
257 5M67 NAD 0.008234 0.43074 14.1791
258 5M67 ADE 0.009051 0.42877 14.1791
259 5M67 3D1 0.009786 0.42714 14.1791
260 4II2 ATP 0.001536 0.41701 14.4578
261 1TPY SAH 0.00000007806 0.57488 14.9254
262 5MPT SAH 0.000001378 0.55925 14.9254
263 1R18 SAH 0.000007152 0.49987 14.978
264 3FZG SAM 0.0000343 0.51088 15
265 5LW0 AR6 0.001698 0.43593 15.5844
266 2EFJ SAH 0.000001588 0.5635 15.6716
267 5THZ SAH 0.000008179 0.53599 16.0448
268 5THY SAH 0.00000594 0.51335 16.0448
269 3DMH SAM 0.00002162 0.48979 16.0448
270 3UCL FAD 0.006421 0.44605 16.0448
271 3DMH GMP 0.000037 0.43908 16.0448
272 5D4V SAH 0.002636 0.42407 16.0448
273 2Q1S NAI 0.01296 0.41712 16.0448
274 3HVJ 705 0.00003788 0.40408 16.2896
275 3VC1 SAH 0.00000004159 0.67145 16.4179
276 4AZW SAM 0.0000005972 0.56212 16.4179
277 2YX1 SFG 0.00005149 0.47163 16.4179
278 3VC1 GST 0.00000004159 0.45498 16.4179
279 4Y2H SAH 0.00003275 0.53469 17.1642
280 4Y2H 49K 0.00005682 0.52353 17.1642
281 3TLJ SAH 0.000001465 0.51715 17.1642
282 1JG3 ADN 0.00002959 0.50209 17.1642
283 1KPG SAH 0.0000001294 0.56706 17.5373
284 2PWY SAH 0.00000734 0.49216 17.8295
285 5E8J SAH 0.000000577 0.59855 18.1818
286 4GQB 0XU 0.00002031 0.46613 18.1818
287 4FZV SAM 0.000144 0.45676 18.2836
288 3OFK SAH 0.0002179 0.44302 18.5185
289 1I1N SAH 0.00000472 0.46726 18.6567
290 4QTU SAM 0.00000002816 0.61691 18.75
291 4XUC SAM 0.00002811 0.53058 18.8073
292 4XUC 43G 0.00002811 0.53058 18.8073
293 5KOK SAH 0.00000004753 0.62525 19.0299
294 5KOK S9T 0.0000009205 0.59867 19.0299
295 5KOK R9T 0.000002754 0.57512 19.0299
296 4M38 SAH 0.00005491 0.47349 19.0476
297 1DL5 SAH 0.00001169 0.46324 19.403
298 5DWQ SFG 0.00001049 0.53346 19.7761
299 5DX0 SFG 0.00001681 0.5265 19.7761
300 3A27 SAM 0.00008114 0.48329 19.7761
301 5FA5 MTA 0.00005028 0.50343 20
302 1KPH SAH 0.0000001672 0.56297 20.1493
303 4RL4 PPV 0.01205 0.41629 20.283
304 3MB5 SAM 0.0000222 0.47625 20.7843
305 1Z3C SA8 0.0000002489 0.49285 20.8955
306 1EJ0 SAM 0.00005177 0.49167 22.7778
307 4R6W SAH 0.0000001639 0.48589 22.8682
308 5MGZ SAH 0.00000002693 0.61708 23.3051
309 1VE3 SAM 0.0000005416 0.57666 23.348
310 5M58 SAH 0.0000001772 0.60057 23.4783
311 2XVM SAH 0.000001076 0.58613 24.1206
312 1LSS NAD 0.00003891 0.47999 26.4286
313 5E1M SAH 0.0000002112 0.62798 26.556
314 5E1M PRO PRO LYS ARG ILE ALA 0.0000002112 0.62798 26.556
315 1IM8 SAI 0.0000005065 0.55376 29.5082
316 4IWN GEK 0.00000008835 0.62236 30.5677
317 3CBG SAH 0.0005053 0.45373 32.3276
318 5DX1 SFG 0.000006858 0.54377 36.8421
319 5DXA SFG 0.000009429 0.48742 36.8421
320 5DX8 SFG 0.000009702 0.48721 36.8421
Pocket No.: 2; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found: 7
This union binding pocket(no: 2) in the query (biounit: 3t7s.bio4) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5G3U ITW 0.01013 0.42308 2.23881
2 4U7W NDP 0.01313 0.4008 2.23881
3 4JCA CIT 0.00583 0.42514 2.39521
4 1CBF SAH 0.009154 0.40198 2.61194
5 1RYO OXL 0.02012 0.40264 3.35821
6 1NVM OXL 0.01995 0.40189 5.59701
7 3NJ4 NAD 0.03173 0.4298 9.70149
Pocket No.: 3; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found: 9
This union binding pocket(no: 3) in the query (biounit: 3t7s.bio3) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1WOG 16D 0.0199 0.40008 2.23881
2 2P9T 3PG 0.02619 0.40129 2.61194
3 2CI5 HCS 0.02765 0.40134 4.47761
4 1EJH M7G 0.0284 0.40337 4.73684
5 1JBW ACQ 0.01559 0.40119 5.97015
6 3CV2 COA 0.02508 0.40668 6.34328
7 1VPE 3PG 0.02836 0.40147 6.34328
8 2WDQ TEO 0.02491 0.40062 7.75194
9 5T46 MGP 0.03633 0.40304 25.7576
Pocket No.: 4; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found: 4
This union binding pocket(no: 4) in the query (biounit: 3t7s.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5HCF BGC 0.02663 0.40957 2.61194
2 5BVE 4VG 0.04072 0.40261 3.87812
3 3WQQ IB3 0.02712 0.40015 4.85075
4 1NJR XYL 0.0006879 0.40034 6.71642
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