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Receptor
PDB id Resolution Class Description Source Keywords
3RYC 2.1 Å NON-ENZYME: OTHER TUBULIN: RB3 STATHMIN-LIKE DOMAIN COMPLEX OVIS ARIES ALPHA-TUBULIN BETA-TUBULIN GTPASE MICROTUBULE STATHMIN SSUBTILISIN TUBULIN CELL CYCLE
Ref.: THE DETERMINANTS THAT GOVERN MICROTUBULE ASSEMBLY F ATOMIC STRUCTURE OF GTP-TUBULIN. J.MOL.BIOL. V. 412 35 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP B:600;
Valid;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
GTP A:600;
D:600;
C:600;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:601;
C:601;
D:601;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
SO4 A:452;
A:453;
A:454;
A:455;
B:456;
B:457;
C:452;
C:453;
D:456;
D:457;
E:146;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3RYC 2.1 Å NON-ENZYME: OTHER TUBULIN: RB3 STATHMIN-LIKE DOMAIN COMPLEX OVIS ARIES ALPHA-TUBULIN BETA-TUBULIN GTPASE MICROTUBULE STATHMIN SSUBTILISIN TUBULIN CELL CYCLE
Ref.: THE DETERMINANTS THAT GOVERN MICROTUBULE ASSEMBLY F ATOMIC STRUCTURE OF GTP-TUBULIN. J.MOL.BIOL. V. 412 35 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3RYI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 3RYC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3RYI - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 3RYC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3RYC - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Ligand no: 2; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3RYC; Ligand: GTP; Similar sites found with APoc: 173
This union binding pocket(no: 1) in the query (biounit: 3ryc.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 1ONX ASP 2.30769
3 3NOJ PYR 2.52101
4 2HZL PYR 2.73973
5 1Q7E MET 3.4965
6 3I0O SMI 3.4965
7 5CKS GAL 3.4965
8 3EW2 BTN 3.7037
9 1TDF FAD 3.79747
10 3B5J 12D 4.04494
11 1FQK ALF 4.1958
12 1BZL FAD 4.1958
13 5A1S FLC 4.1958
14 1BZL GCG 4.1958
15 3W54 RNB 4.1958
16 1XXR MAN 4.34783
17 4Y24 TD2 4.54545
18 5J47 6JJ 4.56989
19 5GOP FRU 4.7191
20 1Z82 G3P 4.77612
21 1Z82 G3H 4.77612
22 4WGF HX2 4.87805
23 4YZ5 DAN 4.8951
24 3CQ5 PMP 4.8951
25 3IHB GLU 4.8951
26 5D63 FUC GAL GLA 5.11945
27 5D63 FUC GLA GLA 5.11945
28 3ZUY TCH 5.26316
29 3KP6 SAL 5.29801
30 2WME NAP 5.32151
31 1B09 PC 5.33981
32 1KJ8 GAR 5.37084
33 4MGA 27L 5.39326
34 3UUA 0CZ 5.39326
35 4MG7 27H 5.39326
36 4MG9 27K 5.39326
37 3THR C2F 5.46075
38 2FLI DX5 5.59441
39 3HYW DCQ 5.59441
40 2HI4 BHF 5.59441
41 5NM7 GLY 5.6391
42 3BY9 SIN 5.76923
43 5V6F MAN BMA MAN 5.7971
44 4O4Z N2O 5.84416
45 1TL2 NDG 5.9322
46 1P4V GLY 6.1017
47 3R75 BEZ 6.29371
48 6APL C5P 6.29371
49 1T9D P22 6.29371
50 6C0B PAM 6.41026
51 5Z2F PDC 6.41509
52 4IEE AGS 6.43016
53 3P2H MTA 6.46766
54 1PJS NAD 6.56455
55 3N8K D1X 6.65188
56 1W5F G2P 6.79887
57 6FLZ MMA 6.87361
58 5CXI 5TW 6.89655
59 1W62 PYC 6.99301
60 2EFX NFA 6.99301
61 4A59 AMP 7.31707
62 2RHO GSP 7.69231
63 1RQ2 CIT 7.69231
64 2RHO GDP 7.69231
65 1LES GLC FRU 7.69231
66 1YFZ IMP 7.69231
67 3S5W NAP 7.69231
68 6CB2 OLC 7.84983
69 4P6G 2FZ 7.9646
70 4IXH Q21 8.03324
71 1VBO MAN 8.05369
72 1VBO MAN MAN MAN 8.05369
73 2FN1 SAL 8.39161
74 2J5V PCA 8.39161
75 1WQ1 AF3 8.39161
76 1NBU PH2 8.40336
77 2CHT TSA 8.66142
78 2BQP GLC 8.97436
79 5OLK DTP 8.98876
80 6DWI HD4 9.01288
81 3CEV ARG 9.0301
82 1IXI 2HP 9.09091
83 1M0S CIT 9.09091
84 2HGS GSH 9.09091
85 4V1F BQ1 9.30233
86 4D86 ADP 9.53437
87 1SQL GUN 9.58904
88 6AM8 TRP 9.59596
89 2W41 ADP 9.7561
90 3DTU DXC 9.79021
91 1S20 TLA 9.79021
92 5TXR PLP 9.79021
93 5FPE 3TR 9.79021
94 1MO9 KPC 9.79021
95 5LJW ANP 10.4895
96 3K56 IS3 10.4895
97 3SAO DBH 10.625
98 2PHF MAN MAN 11.1111
99 1Q8V MAN MAN 11.1111
100 2PHW MAN MAN 11.1111
101 2PHU MAN MAN 11.1111
102 2GND MAN MMA 11.1111
103 1Q8Q MAN MMA 11.1111
104 2PHR MAN MAN 11.1111
105 2PHX MAN MAN 11.1111
106 1Q8P MAN MMA 11.1111
107 2GN3 MAN 11.1111
108 2GNB MAN 11.1111
109 2PHR MAN MAN BMA MAN 11.1111
110 1Q8S MAN MMA 11.1111
111 2PHF MAN MAN BMA MAN 11.1111
112 2PHT MAN MAN MAN BMA MAN 11.1111
113 2GNM MAN 11.1111
114 2PHU MAN MAN MAN BMA MAN 11.1111
115 2PHW MAN MAN MAN BMA MAN MAN MAN 11.1111
116 2GMM MAN MAN 11.1111
117 2GN3 MMA 11.1111
118 2AUY NAG MAN MMA 11.1111
119 2AR6 NAG MAN 11.1111
120 2PHT MAN MAN MAN 11.1111
121 1Q8O MAN MMA 11.1111
122 2GMP NAG MAN 11.1111
123 2GND MAN 11.1111
124 1VKF CIT 11.1888
125 3Q9T FAY 11.1888
126 3HP9 CF1 11.1888
127 1VMK GUN 11.1913
128 1OFS SUC 11.2299
129 1R6N 434 11.3744
130 5EYY MDM 11.4286
131 1XX6 ADP 11.5183
132 2D2F ADP 11.6
133 3G4Q MCH 11.6438
134 3WLV AZA 11.8881
135 4DXD GDP 11.9101
136 5XDT MB3 11.9101
137 5XDT GDP 11.9101
138 3N7S 3N7 12.1739
139 3CGD FAD 12.5874
140 3CGD COA 12.5874
141 3CGD NAD 12.5874
142 1OBD AMP 12.7451
143 1HE1 AF3 13.0682
144 1T0S BML 13.2867
145 1VAY AZA 13.2867
146 1LOB MMA 13.4615
147 1ZK7 FAD 13.7079
148 4XZ3 ACP 13.986
149 1RJW ETF 13.986
150 1ECM TSA 14.6789
151 4EI7 GDP 14.6853
152 2QCX PF1 14.6853
153 2R75 01G 14.7929
154 2VAP GDP 15.1099
155 1OFU GDP 15.3125
156 2VSL MAA LYS PRO PHE 16.6667
157 2HIM ASP 16.7832
158 5IFK HPA 16.7832
159 1RV1 IMZ 17.6471
160 3ITJ CIT 18.1818
161 4YSX MLI 18.1818
162 3ITJ FAD 18.1818
163 5KOD IAC 18.8811
164 3K5I AIR 18.8811
165 6CI9 F3V 19.305
166 4URX FK1 20.2797
167 6BVM EBV 20.2797
168 6BVK EAV 20.2797
169 2Q0L NAP 20.979
170 1HBK COA 23.5955
171 3B8I OXL 23.7762
172 2Q7V FAD 25.1748
173 1JAC AMG 35
Pocket No.: 2; Query (leader) PDB : 3RYC; Ligand: GTP; Similar sites found with APoc: 139
This union binding pocket(no: 2) in the query (biounit: 3ryc.bio1) has 32 residues
No: Leader PDB Ligand Sequence Similarity
1 5XH2 NPO 3.43511
2 5ZBL AMP 3.4965
3 2ACV UDP 3.4965
4 1A27 EST 3.4965
5 5JIL 6KL 3.60825
6 1RTW MP5 4.09091
7 2PUL ACP 4.1958
8 4RP9 ASC 4.1958
9 1TE2 PGA 4.42478
10 5TE1 7A2 4.8951
11 1GDE GLU PLP 4.8951
12 4M2K PLP 4.8951
13 2Q8M AMP 4.8951
14 2FMD MAN MAN 5
15 4TV1 36M 5.39326
16 4TUZ 36J 5.39326
17 4MGD 27N 5.39326
18 6MVU K4V 5.54324
19 2VNO GAL GAL FUC 5.55556
20 4KVL PLM 5.59441
21 2GZM DGL 5.59441
22 2OG7 AHB 5.59441
23 4YNU FAD 5.59441
24 4YNU LGC 5.59441
25 2E2P ADP 5.68562
26 1FDJ 13P 5.78512
27 1NF8 BOG 5.7971
28 2BES RES 5.81395
29 2YVF NAD 5.88235
30 2YVF FAD 5.88235
31 3KC1 2T6 5.93472
32 1PFK ADP 5.9375
33 1M26 GAL A2G 6.01504
34 5CC2 CKA 6.03774
35 2OG2 MLI 6.06742
36 3B9Q MLI 6.29139
37 4HE2 AMP 6.29371
38 2HK9 ATR 6.29371
39 4CIB 7UZ 6.29371
40 3VSV XYP 6.29371
41 2YVJ NAI 6.42202
42 4Q86 AMP 6.51685
43 4ZGM 32M 6.55738
44 1MID LAP 6.59341
45 3WQM B29 6.64452
46 4MOP 2H5 6.74157
47 5O22 C3R 6.92042
48 2I74 MAN MAN MAN MAN 6.99301
49 4M52 M52 6.99301
50 4M52 FAD 6.99301
51 1WPQ 13P 6.99301
52 4XCP PLM 7.05882
53 4CNO 9PY 7.14286
54 1UNQ 4IP 7.2
55 2OZ5 7XY 7.43243
56 5ZZ6 ADP 7.69231
57 5A04 BGC 7.69231
58 2JK0 ASP 7.69231
59 1QVJ RP5 7.69231
60 1TUU AMP 7.69231
61 2I6U CP 7.69231
62 4DNJ ANN 7.69231
63 4MG8 27J 7.86517
64 2IZ1 ATR 8.39161
65 2J5V RGP 8.39161
66 1WUU GLA 8.39161
67 5AJU RP5 8.39416
68 5ZI9 FLC 8.46154
69 4R5M NAP 9.04255
70 2HJR CIT 9.09091
71 1QD0 RR6 9.375
72 4Q6R SIN 9.79021
73 1O9P MLA 9.79021
74 2BNE U5P 9.79021
75 1MO9 FAD 9.79021
76 4IJ6 SEP 9.79021
77 3G5N PB2 9.79021
78 3F8D FAD 9.79021
79 2C3W GLC GLC GLC GLC 9.80392
80 3KOX Z98 9.91736
81 5HUA FK5 10.4348
82 3MMH SME 10.4895
83 2CJP VPR 10.4895
84 4OUE IPT 10.4895
85 1QMG APX 10.4895
86 2BMZ XLM 10.6383
87 3W6G FLC 10.6481
88 1UKG MMA 11.1111
89 5VEQ PMP 11.1888
90 1FHX 4IP 11.6279
91 3TDC 0EU 11.8881
92 2QXL ATP 11.8881
93 2RI1 GLP 11.8881
94 1Q9I TEO 11.8881
95 1Q9I FAD 11.8881
96 3IB1 IMN 12.4638
97 3VPB GLU 12.5
98 2F5Z FAD 12.5
99 4TVD BGC 12.5874
100 2ZGY GDP 12.5874
101 2VT3 ATP 12.5874
102 4KJU 1RH 12.7907
103 6BYF CIT 13.2867
104 4LAY I63 13.2867
105 1X9D SMD 13.2867
106 5LX9 OLB 13.2867
107 3N9R TD3 13.2867
108 5W7B MYR 13.4752
109 3CM2 X23 13.8462
110 5X2N ALA 13.986
111 3VGL ANP 14.3302
112 1ZDQ MSM 14.6853
113 5WS9 OXL 14.6853
114 1O5Q PYR 14.6853
115 6FEA HCA 15.0442
116 4RF7 ARG 15.3846
117 5FII PHE 15.6863
118 1QPB PYM 16.0839
119 1FM9 9CR 16.0839
120 5BWD FUM 16.6667
121 1RO7 CSF 16.7832
122 4YRY FAD 16.7832
123 4EMI NAD 16.7832
124 4PJ3 ANP 16.7832
125 3QVI K95 18.8811
126 4JLS 3ZE 20.2797
127 3ICT ADP 21.6783
128 6ACS CIT 21.6783
129 3ICS ADP 21.6783
130 1JQY A32 22.3301
131 4TQK NAG 23.0769
132 2V7Q ADP 24.2424
133 4OGQ SQD 25.1748
134 1EYQ NAR 25.1748
135 5LWY OLB 27.7311
136 1LOJ URI 32.1839
137 1LOJ U 32.1839
138 3KPE TM3 39.2157
139 1M2Z BOG 47.619
Pocket No.: 3; Query (leader) PDB : 3RYC; Ligand: GDP; Similar sites found with APoc: 153
This union binding pocket(no: 3) in the query (biounit: 3ryc.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 3NOJ PYR 2.52101
3 2WPF WPF 3.32594
4 2WPF FAD 3.32594
5 3I0O SMI 3.4965
6 2WT9 NIO 3.82979
7 1RTW MP5 4.09091
8 4RP9 ASC 4.1958
9 4JGP PYR 4.1958
10 1BZL FAD 4.1958
11 1XXR MAN 4.34783
12 5Y02 HBX 4.6729
13 4WGF HX2 4.87805
14 1E4I NFG 4.8951
15 3CQ5 PMP 4.8951
16 1GDE GLU PLP 4.8951
17 5HY1 WDL 4.8951
18 1SO0 GAL 4.94186
19 3KP6 SAL 5.29801
20 2WME NAP 5.32151
21 4MGA 27L 5.39326
22 4MG9 27K 5.39326
23 3UUA 0CZ 5.39326
24 2NU8 COA 5.41237
25 6MVU K4V 5.54324
26 3V1S 0LH 5.59441
27 5NM7 GLY 5.6391
28 5V6F MAN BMA MAN 5.7971
29 3ETG GWD 5.8427
30 2GWH PCI 5.8427
31 5L7G LYS SER LEU LEU GLN GLN LEU LEU THR GLU 5.90164
32 3KC1 2T6 5.93472
33 2QJT AMP 5.96591
34 5YB7 FAD 6.03448
35 5YB7 ORN 6.03448
36 1FL2 FAD 6.29371
37 1UZ4 IFL 6.29371
38 5YBL AKG 6.29371
39 1T9D P22 6.29371
40 4ZGM 32M 6.55738
41 1PJS NAD 6.56455
42 1MID LAP 6.59341
43 3N8K D1X 6.65188
44 1W5F G2P 6.79887
45 6FLZ MMA 6.87361
46 5CXI 5TW 6.89655
47 1ZGS XMM 6.99301
48 4M52 FAD 6.99301
49 5X7Q GLC GLC GLC GLC 6.99301
50 4M52 M52 6.99301
51 6FP4 E1T 6.99301
52 6FP4 FAD 6.99301
53 2A8X FAD 6.99301
54 2EFX NFA 6.99301
55 1W62 PYC 6.99301
56 3P9T TCL 6.99301
57 2PZI AXX 6.99301
58 2I74 MAN MAN MAN MAN 6.99301
59 1RQ2 CIT 7.69231
60 2RHO GSP 7.69231
61 2RHO GDP 7.69231
62 1TUU AMP 7.69231
63 1RL4 BL5 7.69231
64 2DC1 CIT 7.69231
65 6GAS FAD 7.85498
66 3RNM FAD 7.86517
67 1VBO MAN MAN MAN 8.05369
68 1VBO MAN 8.05369
69 1GET NAP 8.08989
70 1GET FAD 8.08989
71 1QO8 FAD 8.31461
72 2BQP GLC 8.97436
73 5OLK DTP 8.98876
74 1IXI 2HP 9.09091
75 3AB1 FAD 9.09091
76 5LY1 PPI 9.09091
77 4V1F BQ1 9.30233
78 6FYQ PLP 9.31264
79 4D86 ADP 9.53437
80 2W41 ADP 9.7561
81 5TXR PLP 9.79021
82 3F8D FAD 9.79021
83 5HUA FK5 10.4348
84 2B99 RDL 10.4895
85 1Q8Q MAN MMA 11.1111
86 1Q8S MAN MMA 11.1111
87 2PHX MAN MAN 11.1111
88 1Q8V MAN MAN MAN 11.1111
89 2GNM MAN 11.1111
90 1Q8P MAN MMA 11.1111
91 2PHF MAN MAN BMA MAN 11.1111
92 1Q8V MAN MAN 11.1111
93 2PHT MAN MAN MAN BMA MAN 11.1111
94 2PHR MAN MAN BMA MAN 11.1111
95 2PHU MAN MAN 11.1111
96 1Q8O MAN MMA 11.1111
97 2PHU MAN MAN MAN BMA MAN 11.1111
98 2PHR MAN MAN 11.1111
99 2PHW MAN MAN 11.1111
100 2PHT MAN MAN MAN 11.1111
101 2PHF MAN MAN 11.1111
102 1UKG MMA 11.1111
103 2GND MAN MMA 11.1111
104 2PHW MAN MAN MAN BMA MAN MAN MAN 11.1111
105 3HP9 CF1 11.1888
106 1OFS SUC 11.2299
107 1R6N 434 11.3744
108 5EYY MDM 11.4286
109 3G4Q MCH 11.6438
110 1WHT BZS 11.7647
111 1Q9I TEO 11.8881
112 1Q9I FAD 11.8881
113 1D4D FAD 11.8881
114 2RI1 GLP 11.8881
115 4IHL 1F5 11.8881
116 5XDT MB3 11.9101
117 5XDT GDP 11.9101
118 4DXD GDP 11.9101
119 1U08 PLP 12.1762
120 2F5Z FAD 12.5
121 3CGD NAD 12.5874
122 3CGD FAD 12.5874
123 3CGD COA 12.5874
124 1WB4 SXX 12.5874
125 2FPU HSO 13.0682
126 6BYF CIT 13.2867
127 4LAY I63 13.2867
128 5LX9 OLB 13.2867
129 4LAX FK5 13.2867
130 5W7B MYR 13.4752
131 1ZK7 FAD 13.7079
132 3KIF GDL 14.1509
133 4EI7 GDP 14.6853
134 2QCX PF1 14.6853
135 1O5Q PYR 14.6853
136 4RL4 PPV 14.6853
137 1FHW I5P 14.7287
138 2R75 01G 14.7929
139 1E4E PHY 14.8559
140 2VAP GDP 15.1099
141 1OFU GDP 15.3125
142 2RAB NAD 15.3846
143 5O74 GDP 16.1111
144 4GN8 ASO 16.7832
145 3LZW FAD 16.8675
146 3LZW NAP 16.8675
147 1RV1 IMZ 17.6471
148 3ITJ CIT 18.1818
149 4J56 FAD 19.2982
150 4NTD FAD 19.5804
151 4JLS 3ZE 20.2797
152 5C1M OLC 21.6
153 1JQY A32 22.3301
Pocket No.: 4; Query (leader) PDB : 3RYC; Ligand: GTP; Similar sites found with APoc: 55
This union binding pocket(no: 4) in the query (biounit: 3ryc.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 2WPF FAD 3.32594
2 1TDF NAP 3.79747
3 3SI2 PBD 4.1958
4 5GOO FRU 4.7191
5 3GDN HBX 4.94382
6 3GDN FAD 4.94382
7 2ZR9 DTP 5.59441
8 4KYS VIB 5.59441
9 3A06 FOM 5.85106
10 1APZ ASP 6.17284
11 4CP8 MLI 6.29371
12 5W8X UDP 6.29371
13 1FL2 FAD 6.29371
14 1MVQ MMA 6.77966
15 1DKU ABM 6.94006
16 5HV7 RBL 6.99301
17 1YTM OXD 7.09534
18 4ZX2 4TE 7.20721
19 3CTY FAD 7.21003
20 5TCI MLI 7.31707
21 3OEN GLU 7.69231
22 1SL6 GAL NDG FUC 7.69231
23 5DEP UD1 7.75194
24 2AF6 FAD 7.98226
25 1GET NAP 8.08989
26 3WXL ADP 8.39161
27 5EXK MET 8.39161
28 4XDY HIO 8.57988
29 5MIT NAP 9.09091
30 5MIT FAD 9.09091
31 4JZ8 CIT 9.09091
32 3A23 GAL 9.4382
33 1H5R THM 9.55631
34 4URG C2E 9.58084
35 2D09 FLV 9.79021
36 4JNE ATP 9.79021
37 1ONI BEZ 10.1449
38 1C3V PDC 10.4895
39 2BOI MFU 10.6195
40 2PHX MAN MAN MAN MAN 11.1111
41 1Q8V MAN MAN MAN 11.1111
42 1PS9 FAD 11.1888
43 5N1Q COM 11.8774
44 3UEC ALA ARG TPO LYS 11.8881
45 5IN3 G1P 13.217
46 2WW4 ADP 13.2867
47 5FS0 5JC 15.1659
48 2V7B BEZ 15.3846
49 2J0B UDP 16.7832
50 4YKG FAD 16.7832
51 2XA2 UPG 17.4825
52 1DCP HBI 19.2308
53 3K1X DBX 19.2308
54 2BOS GLA GAL GLC 29.4118
55 2BOS GLA GAL GLC NBU 29.4118
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