Receptor
PDB id Resolution Class Description Source Keywords
3RW9 2 Å EC: 2.5.1.16 CRYSTAL STRUCTURE OF HUMAN SPERMIDINE SYNTHASE IN COMPLEX WI DECARBOXYLATED S-ADENOSYLHOMOCYSTEINE HOMO SAPIENS AMINOPROPYLTRANSFERASE TRANSFERASE
Ref.: BINDING AND INHIBITION OF HUMAN SPERMIDINE SYNTHASE DECARBOXYLATED S-ADENOSYLHOMOCYSTEINE. PROTEIN SCI. V. 20 1836 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DSH A:303;
B:303;
Valid;
Valid;
none;
none;
ic50 = 5 uM
340.401 C13 H20 N6 O3 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2O07 1.89 Å EC: 2.5.1.16 HUMAN SPERMIDINE SYNTHASE HOMO SAPIENS SPERMIDINE SYNTHASE STRUCTURAL GENOMICS STRUCTURAL GENOMICS CONSORTIUM SGC TRANSFERASE
Ref.: STRUCTURE AND MECHANISM OF SPERMIDINE SYNTHASES. BIOCHEMISTRY V. 46 8331 2007
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2O05 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
2 3RW9 ic50 = 5 uM DSH C13 H20 N6 O3 S c1nc(c2c(n....
3 2O0L - S4M C14 H24 N6 O3 S C[S@@H](CC....
4 2O07 - SPD C7 H19 N3 C(CCNCCCN)....
5 2O06 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2O05 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
2 3RW9 ic50 = 5 uM DSH C13 H20 N6 O3 S c1nc(c2c(n....
3 2O0L - S4M C14 H24 N6 O3 S C[S@@H](CC....
4 2O07 - SPD C7 H19 N3 C(CCNCCCN)....
5 2O06 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
50% Homology Family (20)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2PWP - SPD C7 H19 N3 C(CCNCCCN)....
2 2I7C ic50 = 8.5 uM AAT C18 H29 N7 O3 S c1nc(c2c(n....
3 2HTE - MTA C11 H15 N5 O3 S CSC[C@@H]1....
4 4YUX Kd = 180 uM 4JT C8 H8 N2 S c1ccc2c(c1....
5 4YV2 - S4M C14 H24 N6 O3 S C[S@@H](CC....
6 4YV1 ic50 = 830 uM 4K2 C15 H16 N2 O2 c1cc2cccnc....
7 5B1S ic50 = 124 uM BSX C8 H10 F N c1ccc(c(c1....
8 4YUZ ic50 = 9.1 uM 4JV C16 H16 N4 O Cc1ccc(cc1....
9 4YUV - S4M C14 H24 N6 O3 S C[S@@H](CC....
10 4YUW ic50 = 1.7 uM 4JU C7 H15 N CC1CCC(CC1....
11 4YV0 ic50 = 530 uM 4JW C16 H15 N O3 CN(c1ccccc....
12 4YUY ic50 = 460 uM 1SQ C9 H8 N2 c1ccc2c(c1....
13 2O05 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
14 3RW9 ic50 = 5 uM DSH C13 H20 N6 O3 S c1nc(c2c(n....
15 2O0L - S4M C14 H24 N6 O3 S C[S@@H](CC....
16 2O07 - SPD C7 H19 N3 C(CCNCCCN)....
17 2O06 - MTA C11 H15 N5 O3 S CSC[C@@H]1....
18 2PT6 - S4M C14 H24 N6 O3 S C[S@@H](CC....
19 2PT9 ic50 = 35 uM 2MH C7 H15 N CC1CCC(CC1....
20 1JQ3 ic50 = 0.2 uM AAT C18 H29 N7 O3 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DSH; Similar ligands found: 210
No: Ligand ECFP6 Tc MDL keys Tc
1 DSH 1 1
2 A7D 0.763889 0.927536
3 3DH 0.761194 0.84507
4 DTA 0.742424 0.833333
5 MTA 0.705882 0.84507
6 SAH 0.692308 0.914286
7 5X8 0.675325 0.885714
8 5N5 0.666667 0.869565
9 ADN 0.661538 0.842857
10 RAB 0.661538 0.842857
11 XYA 0.661538 0.842857
12 S8M 0.635294 0.876712
13 AAT 0.634146 0.943662
14 5CD 0.632353 0.828571
15 A4D 0.632353 0.869565
16 S4M 0.61039 0.906667
17 EP4 0.605634 0.821918
18 SXZ 0.6 0.866667
19 M2T 0.597222 0.8
20 A 0.578947 0.74359
21 AMP 0.578947 0.74359
22 A5D 0.578313 0.833333
23 ZAS 0.558442 0.810811
24 J7C 0.556962 0.863014
25 6RE 0.551282 0.851351
26 SRA 0.551282 0.728395
27 GJV 0.55 0.864865
28 AOC 0.544304 0.819444
29 AMP MG 0.544304 0.725
30 ABM 0.5375 0.725
31 A3N 0.5375 0.859155
32 A2D 0.5375 0.725
33 5AD 0.536232 0.768116
34 MAO 0.52439 0.8
35 BA3 0.52439 0.725
36 AP2 0.52439 0.740741
37 A12 0.52439 0.740741
38 MHZ 0.52381 0.87013
39 ADX 0.52381 0.678161
40 KAA 0.521277 0.75
41 AP5 0.518072 0.725
42 ADP 0.518072 0.725
43 B4P 0.518072 0.725
44 5AS 0.518072 0.696629
45 G5A 0.517241 0.715909
46 AN2 0.511905 0.716049
47 SON 0.511905 0.740741
48 A6D 0.510638 0.740741
49 7D7 0.507042 0.788732
50 Y3J 0.506849 0.746479
51 AU1 0.505882 0.707317
52 CA0 0.505882 0.707317
53 M33 0.505882 0.716049
54 ADP MG 0.505882 0.716049
55 LAD 0.505263 0.8125
56 ADP BEF 0.5 0.698795
57 ACP 0.5 0.728395
58 SFG 0.5 0.871429
59 BEF ADP 0.5 0.698795
60 ATP 0.5 0.725
61 50T 0.5 0.716049
62 XAH 0.494949 0.792683
63 5FA 0.494253 0.725
64 APC 0.494253 0.740741
65 APR 0.494253 0.725
66 PRX 0.494253 0.75
67 AR6 0.494253 0.725
68 AQP 0.494253 0.725
69 EEM 0.488889 0.818182
70 AGS 0.488636 0.710843
71 RBY 0.488636 0.740741
72 ADV 0.488636 0.740741
73 SAP 0.488636 0.710843
74 AD9 0.488636 0.707317
75 SA8 0.488636 0.864865
76 ADP PO3 0.488636 0.74359
77 A3G 0.487805 0.873239
78 NEC 0.487805 0.791667
79 3AM 0.4875 0.730769
80 ATF 0.483516 0.698795
81 A5A 0.483516 0.662921
82 SAI 0.483146 0.875
83 ATP MG 0.483146 0.716049
84 K15 0.479167 0.88
85 SMM 0.478261 0.810127
86 SSA 0.478261 0.696629
87 ACQ 0.477778 0.728395
88 TAT 0.477778 0.719512
89 SAM 0.477778 0.842105
90 GAP 0.477778 0.75
91 ANP 0.477778 0.707317
92 NSS 0.473684 0.677778
93 54H 0.473118 0.648352
94 52H 0.473118 0.641304
95 VMS 0.473118 0.648352
96 TT8 0.473118 0.888889
97 5AL 0.472527 0.716049
98 A3P 0.470588 0.721519
99 62X 0.46875 0.857143
100 5CA 0.468085 0.696629
101 53H 0.468085 0.641304
102 TSB 0.468085 0.655556
103 ALF ADP 0.467391 0.690476
104 ADP ALF 0.467391 0.690476
105 8QN 0.463158 0.716049
106 GEK 0.463158 0.876712
107 25A 0.463158 0.725
108 5SV 0.463158 0.756098
109 7D5 0.4625 0.7125
110 VO4 ADP 0.462366 0.716049
111 SRP 0.462366 0.7625
112 ADP VO4 0.462366 0.716049
113 ANP MG 0.462366 0.690476
114 S7M 0.462366 0.842105
115 TAD 0.461538 0.72619
116 3AD 0.460526 0.855072
117 WAQ 0.459184 0.7875
118 LSS 0.458333 0.663043
119 DSZ 0.458333 0.677778
120 4AD 0.458333 0.731707
121 PAJ 0.458333 0.686047
122 A1R 0.458333 0.810127
123 2AM 0.45679 0.721519
124 ME8 0.454545 0.75
125 BIS 0.454545 0.722892
126 AHX 0.453608 0.73494
127 NVA LMS 0.453608 0.663043
128 DAL AMP 0.452632 0.716049
129 A22 0.452632 0.716049
130 MAP 0.452632 0.690476
131 7MD 0.451923 0.792683
132 LEU LMS 0.44898 0.645161
133 OOB 0.447917 0.716049
134 CC5 0.445946 0.84058
135 QQY 0.445783 0.7
136 V3L 0.445652 0.725
137 GSU 0.444444 0.696629
138 P5A 0.444444 0.761364
139 AMO 0.443299 0.740741
140 0UM 0.443299 0.90411
141 ADQ 0.443299 0.728395
142 A3S 0.443182 0.859155
143 3L1 0.441558 0.871429
144 3D1 0.441558 0.871429
145 OVE 0.440476 0.716049
146 1ZZ 0.44 0.729412
147 TXA 0.44 0.698795
148 PTJ 0.44 0.674419
149 00A 0.438776 0.682353
150 DLL 0.438776 0.716049
151 A2P 0.436782 0.708861
152 MYR AMP 0.435644 0.729412
153 3UK 0.434343 0.707317
154 OAD 0.434343 0.707317
155 ADP BMA 0.434343 0.728395
156 NOC 0.434211 0.785714
157 QQX 0.433735 0.691358
158 A3T 0.433333 0.819444
159 5F1 0.43038 0.828571
160 PR8 0.43 0.825
161 A A 0.43 0.725
162 SP1 0.428571 0.703704
163 RP1 0.428571 0.703704
164 ACK 0.428571 0.714286
165 7MC 0.427273 0.77381
166 JB6 0.425743 0.765432
167 3OD 0.425743 0.707317
168 NB8 0.425743 0.714286
169 FYA 0.425743 0.782051
170 PPS 0.425532 0.659091
171 AR6 AR6 0.424528 0.725
172 PAP 0.423913 0.7125
173 YSA 0.423077 0.677778
174 MTP 0.423077 0.75
175 TYR AMP 0.423077 0.719512
176 KB1 0.421569 0.853333
177 25L 0.421569 0.716049
178 KH3 0.420561 0.893333
179 2BA 0.420455 0.717949
180 CMP 0.420455 0.727273
181 AMP DBH 0.419048 0.707317
182 26A 0.417722 0.783784
183 ARJ 0.417722 0.771429
184 2FA 0.417722 0.786667
185 2VA 0.417582 0.797297
186 9SN 0.417476 0.674419
187 ARG AMP 0.416667 0.761905
188 LAQ 0.416667 0.75
189 ATP A A A 0.413462 0.734177
190 FA5 0.413462 0.740741
191 YAP 0.413462 0.731707
192 LPA AMP 0.412844 0.75
193 4UU 0.411215 0.690476
194 36A 0.409091 0.88
195 7D3 0.409091 0.695122
196 4YB 0.407407 0.681319
197 IOT 0.40708 0.785714
198 4UV 0.40566 0.690476
199 WSA 0.405405 0.685393
200 OMR 0.405405 0.72093
201 649 0.405405 0.722222
202 VRT 0.404255 0.837838
203 SO8 0.404255 0.786667
204 J1A 0.403361 0.871795
205 7C5 0.401869 0.725
206 G3A 0.401869 0.674419
207 YLP 0.4 0.795181
208 1DA 0.4 0.842857
209 6MD 0.4 0.805556
210 IVH 0.4 0.78481
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2O07; Ligand: MTA; Similar sites found: 462
This union binding pocket(no: 1) in the query (biounit: 2o07.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2GUC MAN 0.01018 0.42101 None
2 2NU5 NAG 0.01111 0.41789 None
3 2P41 SAH 0.0003112 0.40609 1.31579
4 3EVG SAH 0.0004226 0.40263 1.45455
5 1AE1 NAP 0.004209 0.40541 1.4652
6 2RGO FAD 0.0001746 0.46544 1.64474
7 2RGH FAD 0.001467 0.43172 1.64474
8 5LD5 NAD 0.002409 0.42 1.64474
9 3GXO SAH 0.008838 0.41542 1.64474
10 1GR0 NAD 0.003751 0.40859 1.64474
11 1WG8 SAM 0.0001081 0.44766 1.75439
12 1O97 AMP 0.009312 0.4107 1.89394
13 3LXD FAD 0.0003357 0.45148 1.92771
14 1MO9 FAD 0.002299 0.44971 1.97368
15 1MO9 KPC 0.003008 0.44513 1.97368
16 2YG3 FAD 0.001062 0.43741 1.97368
17 4KRI SAH 0.0001772 0.42471 1.97368
18 1UXG NAD 0.002959 0.41725 1.97368
19 2HJR APR 0.005269 0.4059 1.97368
20 1Z3C SA8 0.0005244 0.43681 2.01342
21 4DMG SAM 0.00007784 0.52356 2.30263
22 5X62 SAH 0.0001168 0.49787 2.30263
23 2EG5 SAH 0.0008589 0.46756 2.30263
24 3X0D SAH 0.00003054 0.44631 2.30263
25 1YQZ FAD 0.00176 0.44362 2.30263
26 4JNA FAD 0.001266 0.43644 2.30263
27 5F8F SFG 0.003311 0.43539 2.30263
28 5BUK FAD 0.001677 0.43343 2.30263
29 1I8T FAD 0.00139 0.43158 2.30263
30 4RPL 3UC 0.004785 0.42981 2.30263
31 3G5S FAD 0.001584 0.42704 2.30263
32 4RPL FAD 0.005262 0.42609 2.30263
33 4C3Y ANB 0.003121 0.42418 2.30263
34 4C3Y FAD 0.00244 0.42379 2.30263
35 3GGO ENO 0.007273 0.4054 2.30263
36 3GGO NAI 0.007273 0.4054 2.30263
37 2DT5 NAD 0.001465 0.41186 2.36967
38 1S7G APR 0.0007114 0.43589 2.37154
39 1S7G NAD 0.003447 0.40629 2.37154
40 4RDH AMP 0.0004443 0.47616 2.43056
41 3GDH SAH 0.00002494 0.49757 2.48963
42 5O4J SAH 0.002499 0.41559 2.55474
43 5O4J 9KH 0.002499 0.41559 2.55474
44 5O4J PJL 0.002334 0.41552 2.55474
45 3FUU ADN 0.00003093 0.44477 2.58303
46 1J2Z SOG 0.02462 0.40866 2.59259
47 5HJM MTA 0.0001424 0.48408 2.63158
48 4OPC PGT 0.002292 0.46036 2.63158
49 4OPC FDA 0.002088 0.45893 2.63158
50 3KLJ FAD 0.0002226 0.4558 2.63158
51 4C4A SAH 0.00003135 0.44551 2.63158
52 2V3A FAD 0.0007231 0.44189 2.63158
53 2V3B FAD 0.0007346 0.44043 2.63158
54 3TLJ SAH 0.0009013 0.43769 2.63158
55 4BJZ P3A 0.005268 0.42984 2.63158
56 2YVF NAD 0.005485 0.42398 2.63158
57 1OC2 NAD 0.00499 0.42218 2.63158
58 1KNR FAD 0.002646 0.42133 2.63158
59 2YVF FAD 0.0067 0.41958 2.63158
60 1O94 ADP 0.00215 0.41889 2.63158
61 4UP4 GAL NAG 0.02628 0.41282 2.63158
62 4NTC FAD 0.004732 0.41208 2.63158
63 4MIG G3F 0.008197 0.40846 2.63158
64 2YY7 NAD 0.003449 0.40629 2.63158
65 2YX1 SFG 0.0001125 0.4057 2.63158
66 3H8V ATP 0.0005243 0.4017 2.63158
67 2DTX BMA 0.005717 0.40675 2.65152
68 3PFG TLO 0.005904 0.40718 2.6616
69 3OID NDP 0.004922 0.40272 2.71318
70 4YMZ 13P 0.01413 0.42114 2.78884
71 3GCZ SAM 0.0002391 0.40992 2.83688
72 1I9G SAM 0.0000388 0.4464 2.85714
73 3EVF SAH 0.00281 0.41592 2.88809
74 3EVF GTA 0.003595 0.4149 2.88809
75 3EGI ADP 0.000002233 0.62577 2.91262
76 4D04 NAP 0.00119 0.45311 2.96053
77 3ICR FAD 0.000362 0.45275 2.96053
78 1BZL FAD 0.003086 0.45081 2.96053
79 3ICS FAD 0.0004722 0.44934 2.96053
80 3ICT FAD 0.0004678 0.44829 2.96053
81 3HDY FDA 0.002781 0.43661 2.96053
82 3HDY GDU 0.002887 0.43661 2.96053
83 3HDY FAD 0.002837 0.43623 2.96053
84 2NVK FAD 0.001302 0.43489 2.96053
85 3S1S SAH 0.001088 0.4343 2.96053
86 3UCL NAP 0.005978 0.42624 2.96053
87 2X3N FAD 0.002108 0.42207 2.96053
88 3UCL CYH 0.007133 0.42105 2.96053
89 3UCL FAD 0.007133 0.42105 2.96053
90 2RGJ FAD 0.002315 0.41566 2.96053
91 3FG2 FAD 0.002661 0.41327 2.96053
92 5KOK SAH 0.006705 0.41063 2.96053
93 3CIF G3H 0.004032 0.40852 2.96053
94 3CIF NAD 0.003141 0.40516 2.96053
95 2IVD FAD 0.0003723 0.40328 2.96053
96 1XCL SAH 0.00001974 0.4646 2.97872
97 1XHC FAD 0.0002383 0.45874 2.99728
98 2ZIF SAM 0.00001623 0.45083 3.0303
99 4II2 ATP 0.0002243 0.42236 3.06748
100 1JQD HSM 0.0008924 0.42789 3.08219
101 2AOT SAH 0.0001115 0.41441 3.08219
102 1JQD SAH 0.001022 0.41316 3.08219
103 4R6W PC 0.002127 0.43542 3.10078
104 4R6W SAH 0.0009812 0.42904 3.10078
105 5OFW 9TW 0.007757 0.44101 3.13901
106 3DUW SAH 0.0002203 0.4168 3.13901
107 4NTD FAD 0.0003129 0.45653 3.23529
108 1EDO NAP 0.002612 0.41232 3.27869
109 1PR9 NAP 0.004956 0.4026 3.27869
110 3RNM FAD 0.0001952 0.4707 3.28947
111 4M52 FAD 0.0002736 0.46358 3.28947
112 1U1I NAD 0.0003478 0.44953 3.28947
113 3LZW NAP 0.001423 0.44679 3.28947
114 3LZW FAD 0.0007788 0.4406 3.28947
115 5KJW 53C 0.01453 0.43178 3.28947
116 2AQJ FAD 0.003364 0.43165 3.28947
117 2AQJ TRP 0.003233 0.43165 3.28947
118 1ZMD NAI 0.001009 0.42896 3.28947
119 1OBB NAD 0.001372 0.42682 3.28947
120 2EJU SAH 0.00008466 0.42599 3.28947
121 2B4R NAD 0.001696 0.41836 3.28947
122 2B4R AES 0.001605 0.4179 3.28947
123 1ORR NAD 0.002161 0.41684 3.28947
124 3SSO SAH 0.0005604 0.41111 3.28947
125 3WE0 FAD 0.006408 0.40858 3.28947
126 2VYN NAD 0.002872 0.40667 3.28947
127 2YGM GLA NAG GAL FUC 0.03228 0.40254 3.28947
128 2CUL FAD 0.0005778 0.4421 3.44828
129 1P1C SAH 0.000004169 0.49303 3.51759
130 1R18 SAH 0.0000398 0.45229 3.52423
131 5N53 8NB 0.001536 0.47944 3.58974
132 5KVA SAM 0.0001032 0.43872 3.59712
133 3SQP FAD 0.002288 0.47564 3.61842
134 2HQM FAD 0.0001636 0.4727 3.61842
135 4CNK FAD 0.0004086 0.45187 3.61842
136 4PIO SAH 0.0004769 0.4441 3.61842
137 4PIO AVI 0.0004756 0.44279 3.61842
138 5DX0 SFG 0.0002014 0.4408 3.61842
139 1RSG FAD 0.001061 0.43957 3.61842
140 4USR FAD 0.0006261 0.43808 3.61842
141 1YY5 FAD 0.001448 0.43606 3.61842
142 5DWQ SFG 0.0002393 0.43334 3.61842
143 5MBX FAD 0.003373 0.4286 3.61842
144 5MBX SP5 0.003373 0.4286 3.61842
145 1YBH FAD 0.001722 0.42782 3.61842
146 4AT0 FAD 0.002819 0.4269 3.61842
147 4K5S PM0 0.003412 0.42432 3.61842
148 4K5S FAD 0.001397 0.42432 3.61842
149 5M67 NAD 0.003682 0.42294 3.61842
150 5M67 ADE 0.004179 0.42065 3.61842
151 5M67 3D1 0.004651 0.41872 3.61842
152 1UDB NAD 0.005474 0.4174 3.61842
153 5XVQ SAH 0.003137 0.41524 3.61842
154 2WLT ASP 0.0203 0.41301 3.61842
155 1F3L SAH 0.0005367 0.41139 3.61842
156 5MQ6 NDP 0.004525 0.40864 3.61842
157 4CQB MLI 0.03518 0.40811 3.61842
158 1SB8 NAD 0.009459 0.40506 3.61842
159 1SB8 UD2 0.01124 0.40506 3.61842
160 3LKZ SFG 0.0005365 0.40388 3.61842
161 1U2Z SAH 0.001397 0.40039 3.61842
162 3NUG NAD 0.003116 0.40801 3.64372
163 1JA9 NDP 0.005201 0.40055 3.64964
164 5IL1 SAM 0.01217 0.40229 3.66667
165 5FA8 SAM 0.000226 0.46256 3.72671
166 4J4H NAI 0.007317 0.40885 3.861
167 4J4H 1J1 0.007317 0.40885 3.861
168 1G0N NDP 0.002797 0.41824 3.88693
169 1G0N PHH 0.003445 0.41769 3.88693
170 3H2B SAH 0.0003526 0.40809 3.94089
171 5FA5 MTA 0.00007374 0.5126 3.94737
172 3AYI FAD 0.00049 0.46214 3.94737
173 3AYI HCI 0.0005145 0.46214 3.94737
174 3E1T FAD 0.0006046 0.4506 3.94737
175 3NTD FAD 0.0009711 0.43674 3.94737
176 4GQB 0XU 0.0002184 0.43591 3.94737
177 1J0X NAD 0.004533 0.41475 3.94737
178 1DLJ NAI 0.0083 0.40904 3.94737
179 3V1Y NAD 0.002805 0.40838 3.94737
180 5VN0 NAI 0.003087 0.40674 3.94737
181 4B7E OGA 0.03738 0.40319 3.94737
182 3ELW GP3 0.00154 0.43295 4
183 3ELW SAM 0.001699 0.43019 4
184 3WV8 ATP 0.00008642 0.43124 4.12844
185 3U31 NAD 0.005926 0.40672 4.13793
186 1KPG SAH 0.002676 0.42132 4.18118
187 2B9W FAD 0.009213 0.4109 4.24528
188 5FJN FAD 0.0008638 0.44321 4.27632
189 5FJN BE2 0.001025 0.44321 4.27632
190 5N5D SAM 0.0001206 0.42495 4.27632
191 1PS9 FAD 0.003799 0.41596 4.27632
192 3CMC NAD 0.01867 0.40356 4.27632
193 1ZBQ NAD 0.002291 0.41456 4.28135
194 5ITV NAI 0.001611 0.41923 4.31373
195 3A25 SAM 0.0001419 0.41773 4.31894
196 2WSB NAD 0.00383 0.41481 4.33071
197 4QTU SAM 0.0005199 0.45941 4.44444
198 3FZG SAM 0.007137 0.41977 4.5
199 1IM8 SAI 0.0009917 0.44323 4.5082
200 5JJR SAH 0.0006671 0.45887 4.60526
201 3CGD NAD 0.0015 0.45728 4.60526
202 3CGD COA 0.0015 0.45728 4.60526
203 3CGD FAD 0.0015 0.45728 4.60526
204 4FWE FAD 0.0004426 0.45614 4.60526
205 1G55 SAH 0.001321 0.44164 4.60526
206 3GDN HBX 0.001616 0.43957 4.60526
207 3GDN FAD 0.00106 0.43957 4.60526
208 4DSG UDP 0.003945 0.42941 4.60526
209 4DSG FAD 0.004364 0.42891 4.60526
210 4EIP FAD 0.002201 0.42858 4.60526
211 1ELI PYC 0.001773 0.42621 4.60526
212 4EIP K2C 0.003923 0.42007 4.60526
213 1VDC FAD 0.00665 0.41142 4.60526
214 4J36 FAD 0.003194 0.41014 4.60526
215 4J36 1HR 0.006195 0.40918 4.60526
216 2AE2 NAP 0.007757 0.40236 4.61538
217 1Q0S SAH 0.0002065 0.43739 4.6332
218 1N4W FAD 0.0003531 0.46016 4.93421
219 1RYI FAD 0.0006491 0.44719 4.93421
220 1QO8 FAD 0.0009624 0.44129 4.93421
221 3S5W FAD 0.000836 0.43037 4.93421
222 4EUE NAI 0.001007 0.42859 4.93421
223 2Q1S NAI 0.003109 0.42147 4.93421
224 5T67 JHZ 0.00363 0.42056 4.93421
225 5T67 SAH 0.003312 0.41738 4.93421
226 5MW4 5JU 0.00367 0.41557 4.93421
227 1MV8 NAD 0.00294 0.40177 4.93421
228 1MUU NAD 0.005113 0.4008 4.93421
229 2Q28 ADP 0.0007044 0.40045 4.93421
230 1XXR MAN 0.02749 0.41011 4.96894
231 3BGD PM6 0.0003903 0.43865 5
232 3BGD SAH 0.0008087 0.41164 5
233 3DXY SAM 0.000005953 0.43461 5.04587
234 3AD8 NAD 0.0004009 0.44709 5.05051
235 3AD8 FAD 0.003779 0.43359 5.05051
236 2PXX SAH 0.0005251 0.40439 5.11628
237 5CUQ NSC 0.001127 0.42667 5.24345
238 1X87 NAD 0.00002378 0.46705 5.26316
239 4NEC SAH 0.001091 0.45792 5.26316
240 3QVP FAD 0.0006148 0.4503 5.26316
241 5E72 SAM 0.0001877 0.43104 5.26316
242 1YKJ FAD 0.0045 0.42834 5.26316
243 1V5F FAD 0.005841 0.42414 5.26316
244 2O4C NAD 0.002653 0.41075 5.26316
245 1V6A TRE 0.04522 0.40005 5.26316
246 5JE8 NAD 0.001977 0.4173 5.29801
247 4CQM NAP 0.004284 0.40128 5.36398
248 1EJ0 SAM 0.0001697 0.41848 5.55556
249 3QWI CUE 0.003373 0.41807 5.55556
250 3QWI NAP 0.002281 0.41463 5.55556
251 3VYW SAM 0.00006099 0.49533 5.59211
252 2C7G ODP 0.0008893 0.453 5.59211
253 2C7G FAD 0.0009305 0.453 5.59211
254 2FN1 SAL 0.00727 0.43602 5.59211
255 5EB4 FAD 0.001288 0.43402 5.59211
256 3UOY NAP 0.004441 0.43121 5.59211
257 1NSA BEN 0.005438 0.42491 5.59211
258 3NT6 FAD 0.002007 0.42404 5.59211
259 3VSE SAH 0.00003218 0.41492 5.59211
260 2Q0L NAP 0.01226 0.40874 5.59211
261 3QSB 743 0.02652 0.40315 5.59211
262 5UDS ATP 0.02632 0.40331 5.59441
263 1I1N SAH 0.0002866 0.44382 5.75221
264 5JCM NAD 0.001042 0.45702 5.76497
265 5JCM FAD 0.001003 0.45702 5.76497
266 5JCM ISD 0.001042 0.45702 5.76497
267 4OBW SAM 0.00007441 0.50152 5.83658
268 3A4T SFG 0.0001587 0.43413 5.83942
269 2HNK SAH 0.000303 0.4185 5.85774
270 4BLW AMP 0.0004981 0.44335 5.88235
271 4BLW SAH 0.0005182 0.43082 5.88235
272 4USQ FAD 0.0003875 0.44767 5.92105
273 3LST SAH 0.005283 0.42984 5.92105
274 3NJ4 NAD 0.01384 0.42785 5.92105
275 3ITJ FAD 0.006321 0.41317 5.92105
276 1T26 NAI 0.007644 0.40452 5.92105
277 3NJ4 AFX 0.04427 0.40437 5.92105
278 4XFR CIT 0.03638 0.4036 5.92105
279 1JG3 ADN 0.000004969 0.55414 5.95745
280 1I7M CG 0.01689 0.41714 5.97015
281 4POO SAM 0.001958 0.40252 6
282 2VDV SAM 0.00008256 0.51614 6.09756
283 4D79 ATP 0.0009526 0.45193 6.15942
284 1KYQ NAD 0.00017 0.41636 6.20438
285 3DMH SAM 0.0001437 0.47932 6.25
286 1REO FAD 0.0002981 0.45859 6.25
287 3CGB FAD 0.0004078 0.45068 6.25
288 3DMH GMP 0.0002332 0.44727 6.25
289 3GD4 NAD 0.00234 0.44702 6.25
290 3GD4 FAD 0.001596 0.44467 6.25
291 2VVM FAD 0.001131 0.4363 6.25
292 5MPT SAH 0.002959 0.42988 6.25
293 3TKA SAM 0.0003313 0.41724 6.25
294 3OJO NAD 0.0006371 0.41412 6.25
295 2PZM NAD 0.006174 0.40924 6.25
296 2PZM UDP 0.006174 0.40924 6.25
297 4K28 NAD 0.00611 0.40041 6.3197
298 2YVJ FAD 0.004413 0.40918 6.42202
299 3GEG NAD 0.001085 0.42154 6.47773
300 1JNR FAD 0.001041 0.46241 6.57895
301 2CDU FAD 0.0002137 0.46062 6.57895
302 1H82 GZZ 0.001287 0.45091 6.57895
303 1H82 FAD 0.001358 0.44686 6.57895
304 2BRY FAD 0.0007435 0.43513 6.57895
305 3IHG FAD 0.001278 0.4203 6.57895
306 3NDJ JHZ 0.003944 0.41997 6.57895
307 3NDJ SAH 0.003944 0.41997 6.57895
308 4TXI FAD 0.0005762 0.41185 6.57895
309 3EYA FAD 0.004762 0.40563 6.57895
310 2C31 TZD 0.02046 0.40464 6.57895
311 2C31 ADP 0.01991 0.40461 6.57895
312 1KOL NAD 0.005959 0.40286 6.57895
313 5ULP KB1 0.0002776 0.45503 6.71642
314 5BW4 SAM 0.0001026 0.41742 6.74157
315 1ZEM NAD 0.0008269 0.42283 6.87023
316 3LAD FAD 0.0002498 0.4652 6.90789
317 5C9J DAO 0.02119 0.40808 7.07071
318 1R6D NAD 0.009654 0.40858 7.23684
319 4KIB SAH 0.0002162 0.40845 7.23684
320 1R6D DAU 0.01229 0.40342 7.23684
321 1U7T TDT 0.006325 0.40694 7.27969
322 3OFK SAH 0.000999 0.43939 7.40741
323 4M73 M72 0.00006718 0.48207 7.56579
324 4M73 SAH 0.0001112 0.47196 7.56579
325 4UP3 FAD 0.004236 0.41304 7.56579
326 1WY7 SAH 0.0003116 0.41863 7.72947
327 1Y8Q ATP 0.000094 0.47414 7.89474
328 1GET FAD 0.0005845 0.46855 7.89474
329 1GET NAP 0.0006306 0.46855 7.89474
330 3T31 DCQ 0.000807 0.45643 7.89474
331 3T31 FAD 0.0007372 0.45643 7.89474
332 1GY8 NAD 0.002929 0.40906 7.89474
333 4YMH SAH 0.0002557 0.46855 7.91667
334 2OBF F83 0.001739 0.43081 7.95848
335 2EWM NAD 0.003037 0.40845 8.03213
336 3A27 SAM 0.00008149 0.49975 8.08823
337 2PWY SAH 0.00005503 0.45121 8.13953
338 1V59 FAD 0.0001588 0.47657 8.159
339 1V59 NAD 0.0000112 0.42783 8.159
340 1UWK URO 0.00008259 0.48826 8.22368
341 1UWK NAD 0.00008259 0.48826 8.22368
342 3L9W AMP 0.0001299 0.462 8.22368
343 3L9W GSH 0.0001273 0.45909 8.22368
344 3F8D FAD 0.003422 0.43799 8.55263
345 2WET FAD 0.001137 0.43729 8.55263
346 1D4D FAD 0.001351 0.4363 8.55263
347 3L4S 3PG 0.003504 0.40855 8.55263
348 3L4S NAD 0.003257 0.40855 8.55263
349 3Q87 SAM 0.001366 0.40464 8.8
350 3GRU AMP 0.00005148 0.45491 8.81356
351 4GUT FAD 0.0004077 0.46071 8.87097
352 4HSU FAD 0.0003665 0.46056 8.87097
353 4GUS FAD 0.0003885 0.45953 8.87097
354 4Y2H SAH 0.0005111 0.44914 8.88158
355 4Y2H 49K 0.0007397 0.44265 8.88158
356 1VQW FAD 0.001057 0.4291 8.88158
357 2GVC FAD 0.001183 0.42717 8.88158
358 1NW5 SAM 0.0004801 0.40556 8.88158
359 2DFV NAD 0.003157 0.40365 8.88158
360 2DPM SAM 0.000172 0.43241 9.15493
361 5E8J SAH 0.0008342 0.46817 9.21053
362 3CTY FAD 0.003212 0.42183 9.21053
363 1J49 NAD 0.004001 0.40108 9.21053
364 1M2K APR 0.003272 0.40305 9.23695
365 1XDS SAM 0.0004575 0.48063 9.35829
366 1E6E FAD 0.001287 0.42948 9.375
367 1QAN SAH 0.0003701 0.4193 9.42623
368 4WEY EG6 0.007964 0.41057 9.52381
369 4BV6 FAD 0.0005932 0.44878 9.53947
370 1N2X SAM 0.001244 0.40802 9.63455
371 4M38 SAH 0.0001125 0.48389 9.86842
372 4AP3 NAP 0.0005558 0.46572 9.86842
373 1DL5 SAH 0.0001389 0.45118 9.86842
374 4TM3 FAD 0.003277 0.43756 9.86842
375 4M37 SAH 0.00009386 0.43304 9.86842
376 2DKH FAD 0.001156 0.42757 9.86842
377 2DKH 3HB 0.001809 0.42696 9.86842
378 4D7E FAD 0.0005644 0.40085 9.86842
379 1UP7 NAD 0.0004472 0.42913 10.1974
380 2FK8 SAM 0.002128 0.42896 10.1974
381 2XYQ SAH 0.0004654 0.40597 10.3448
382 3SHR CMP 0.02056 0.40875 10.3679
383 5E1M SAH 0.001018 0.44274 10.3734
384 3HVJ 705 0.0001618 0.46677 10.4072
385 4REP FAD 0.0006772 0.4442 10.5263
386 5JE0 AZ8 0.001197 0.4061 10.5263
387 5JE0 SAH 0.001197 0.4061 10.5263
388 3G2O SAM 0.0001355 0.48986 10.7023
389 3G89 SAM 0.00002467 0.54119 10.8434
390 4EMI NAD 0.002183 0.44038 10.8553
391 4EMI FAD 0.0008296 0.43949 10.8553
392 1SQF SAM 0.00006446 0.43401 10.8553
393 2Z3Y F2N 0.001867 0.43054 10.8553
394 5THY SAH 0.002349 0.42711 10.8553
395 2Y6Q FAD 0.001802 0.41866 10.8553
396 2Y6Q I7T 0.00454 0.41744 10.8553
397 1K3T BRZ 0.005338 0.40133 11.1842
398 4EMJ FAD 0.001048 0.43654 11.215
399 3EGV SAH 0.00009878 0.5012 11.4173
400 2NXE SAM 0.0002479 0.47811 11.4173
401 1XTP SAI 0.0003704 0.40384 11.4173
402 5DLY SAH 0.0001525 0.41017 11.6541
403 5DLY 5D7 0.0001623 0.40184 11.6541
404 2RAB FAD 0.0002036 0.47104 11.8421
405 2RAB NAD 0.0005127 0.471 11.8421
406 4YNU LGC 0.0008229 0.45001 11.8421
407 4YNU FAD 0.0006759 0.44965 11.8421
408 2XVE FAD 0.003603 0.43109 11.8421
409 2XVF FAD 0.001265 0.43096 11.8421
410 1TDF NAP 0.01336 0.41221 11.8421
411 1TDF FAD 0.007 0.40965 11.8421
412 1RP0 AHZ 0.0004055 0.44411 11.9718
413 4FZV SAM 0.00003963 0.44908 12.1339
414 1LTH NAD 0.003536 0.40175 12.1711
415 5L95 AMP 0.001186 0.44368 12.5
416 1FEC FAD 0.001068 0.44343 12.5
417 1FL2 FAD 0.001883 0.42625 12.5
418 3FPF MTA 0.00006759 0.48462 12.7517
419 3FPF TNA 0.00006759 0.41348 12.7517
420 3M6W SAM 0.007962 0.41754 12.8289
421 4UCI SAM 0.0007389 0.40139 13.012
422 1VKO NAD 0.001338 0.4009 13.1579
423 4N49 SAM 0.0003668 0.41754 13.3178
424 2E5V FAD 0.002091 0.42853 13.4868
425 1ZQ9 SAM 0.000008577 0.46136 13.6842
426 3PT9 SAH 0.0003185 0.40427 13.8158
427 1LVL NAD 0.00006568 0.49395 13.9738
428 2WPF FAD 0.001201 0.46874 14.1447
429 2WPF WPF 0.001532 0.46547 14.1447
430 5MGZ SAH 0.00131 0.4418 14.4068
431 1V8B NAD 0.003897 0.41024 14.4737
432 2JJQ SAH 0.0001901 0.49884 14.8026
433 2HMT NAI 0.0003459 0.4207 15.2778
434 1QD0 RR6 0.009379 0.42179 15.625
435 1NV8 SAM 0.0001082 0.46184 15.8451
436 1NV8 MEQ 0.00009764 0.46184 15.8451
437 5XVK SAH 0.002582 0.41875 15.8451
438 3MB5 SAM 0.0002871 0.42779 16.4706
439 4XUC 43G 0.0004607 0.44469 16.9725
440 4XUC SAM 0.0004607 0.44469 16.9725
441 2VHW NAI 0.004028 0.40967 17.7632
442 1X7D ORN 0.003 0.41591 18.0921
443 1X7D NAD 0.003046 0.40568 18.0921
444 3ZNN 4WL 0.003604 0.42891 18.4211
445 3ZNN FAD 0.003604 0.42891 18.4211
446 3WGT FAD 0.002609 0.42829 18.4211
447 3WGT QSC 0.002808 0.42784 18.4211
448 2F5Z FAD 0.0001309 0.47779 18.75
449 5TVF CGQ 0.02307 0.40255 18.8235
450 1LSS NAD 0.0000433 0.44694 20
451 5LOG SAH 0.0001364 0.42446 21.03
452 1L3I SAH 0.0001277 0.45287 21.875
453 3CBG SAH 0.00008963 0.4194 21.9828
454 2GAG NAD 0.0005632 0.44505 23.2323
455 2GAG FAD 0.001546 0.43585 23.2323
456 2GAG FOA 0.001636 0.43484 23.2323
457 4J56 FAD 0.001691 0.43329 26.3158
458 3C6K SPD 0.0000000001111 0.71156 30.5921
459 3C6K MTA 0.0000000001111 0.71156 30.5921
460 5DXA SFG 0.0005247 0.44742 31.5789
461 5DX8 SFG 0.0006246 0.44428 31.5789
462 5DX1 SFG 0.0006102 0.42282 31.5789
Pocket No.: 2; Query (leader) PDB : 2O07; Ligand: SPD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2o07.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2O07; Ligand: SPD; Similar sites found: 414
This union binding pocket(no: 3) in the query (biounit: 2o07.bio1) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2GUC MAN 0.01118 0.42101 None
2 2RGO FAD 0.000208 0.45571 1.64474
3 2RGH FAD 0.001648 0.42415 1.64474
4 5LD5 NAD 0.002642 0.42117 1.64474
5 3GXO SAH 0.01005 0.41542 1.64474
6 1GR0 NAD 0.004589 0.40016 1.64474
7 1WG8 SAM 0.0001306 0.43387 1.75439
8 1O97 AMP 0.01179 0.40193 1.89394
9 3LXD FAD 0.0004867 0.43886 1.92771
10 1MO9 FAD 0.002975 0.43959 1.97368
11 1MO9 KPC 0.003842 0.43539 1.97368
12 2YG3 FAD 0.00149 0.42587 1.97368
13 4KRI SAH 0.000211 0.41172 1.97368
14 1UXG NAD 0.00372 0.40818 1.97368
15 2HJR APR 0.006119 0.4059 1.97368
16 1Z3C SA8 0.001416 0.41441 2.01342
17 4DMG SAM 0.00009472 0.52279 2.30263
18 5X62 SAH 0.0001381 0.49787 2.30263
19 2EG5 SAH 0.0009926 0.46756 2.30263
20 5BUK FAD 0.000855 0.43956 2.30263
21 5F8F SFG 0.003796 0.43539 2.30263
22 1YQZ FAD 0.002323 0.43316 2.30263
23 3X0D SAH 0.00003679 0.43209 2.30263
24 4JNA FAD 0.001961 0.42325 2.30263
25 1I8T FAD 0.001891 0.42074 2.30263
26 4RPL 3UC 0.006106 0.42043 2.30263
27 4RPL FAD 0.006153 0.41838 2.30263
28 3G5S FAD 0.001985 0.41769 2.30263
29 4C3Y FAD 0.003131 0.41422 2.30263
30 4C3Y ANB 0.004325 0.41333 2.30263
31 3AXB FAD 0.0004494 0.40322 2.30263
32 2DT5 NAD 0.001914 0.41216 2.36967
33 1S7G APR 0.001191 0.42135 2.37154
34 4RDH AMP 0.0005179 0.47616 2.43056
35 3GDH SAH 0.00003055 0.49757 2.48963
36 5O4J SAH 0.00308 0.40681 2.55474
37 5O4J 9KH 0.00308 0.40681 2.55474
38 5O4J PJL 0.003027 0.40588 2.55474
39 3FUU ADN 0.00003726 0.43042 2.58303
40 1J2Z SOG 0.02572 0.41013 2.59259
41 5HJM MTA 0.0001693 0.48408 2.63158
42 4OPC PGT 0.00231 0.45487 2.63158
43 4OPC FDA 0.002394 0.45095 2.63158
44 3KLJ FAD 0.0003267 0.4428 2.63158
45 3TLJ SAH 0.001064 0.43769 2.63158
46 2V3A FAD 0.0007186 0.43601 2.63158
47 2V3B FAD 0.0008837 0.43134 2.63158
48 4C4A SAH 0.00003776 0.4313 2.63158
49 4BJZ P3A 0.005956 0.42271 2.63158
50 1O94 ADP 0.002571 0.41856 2.63158
51 4MIG G3F 0.003751 0.41754 2.63158
52 1OC2 NAD 0.005809 0.41457 2.63158
53 1KNR FAD 0.002904 0.41449 2.63158
54 2YVF NAD 0.00738 0.41378 2.63158
55 4UP4 GAL NAG 0.02886 0.41282 2.63158
56 2YVF FAD 0.007675 0.4124 2.63158
57 4NTC FAD 0.005396 0.40489 2.63158
58 3PFG TLO 0.00503 0.40511 2.6616
59 1I9G SAM 0.00004682 0.43177 2.85714
60 3EVF GTA 0.002461 0.41626 2.88809
61 3EVF SAH 0.004107 0.40432 2.88809
62 3EGI ADP 0.000002659 0.62577 2.91262
63 4D04 NAP 0.001325 0.44545 2.96053
64 3ICR FAD 0.0005442 0.43951 2.96053
65 1BZL FAD 0.004454 0.43868 2.96053
66 3ICS FAD 0.0007102 0.43621 2.96053
67 3S1S SAH 0.001282 0.4343 2.96053
68 3ICT FAD 0.0008362 0.43227 2.96053
69 3HDY GDU 0.003384 0.42853 2.96053
70 3HDY FDA 0.003256 0.42853 2.96053
71 3HDY FAD 0.003376 0.42788 2.96053
72 2NVK FAD 0.001794 0.42375 2.96053
73 3UCL NAP 0.007093 0.41831 2.96053
74 3UCL FAD 0.007368 0.41575 2.96053
75 3UCL CYH 0.007368 0.41575 2.96053
76 2X3N FAD 0.002802 0.41188 2.96053
77 5KOK SAH 0.007705 0.41063 2.96053
78 2RGJ FAD 0.003019 0.40592 2.96053
79 2ZXI FAD 0.0004636 0.40581 2.96053
80 2IVD FAD 0.0005266 0.40526 2.96053
81 3FG2 FAD 0.003549 0.40324 2.96053
82 1TV5 N8E 0.04344 0.40278 2.96053
83 1XCL SAH 0.00003286 0.4646 2.97872
84 1XHC FAD 0.0003494 0.4457 2.99728
85 2ZIF SAM 0.00001966 0.43613 3.0303
86 4II2 ATP 0.0002665 0.40982 3.06748
87 1JQD HSM 0.0008529 0.43169 3.08219
88 1JQD SAH 0.001104 0.41848 3.08219
89 2AOT SAH 0.0001366 0.40182 3.08219
90 4R6W PC 0.002677 0.42598 3.10078
91 4R6W SAH 0.001438 0.41691 3.10078
92 5OFW 9TW 0.008649 0.44101 3.13901
93 3DUW SAH 0.0002609 0.40428 3.13901
94 4NTD FAD 0.0004769 0.44295 3.23529
95 1EDO NAP 0.003448 0.40247 3.27869
96 3RNM FAD 0.0003048 0.4563 3.28947
97 4M52 FAD 0.0003911 0.45092 3.28947
98 3SSO SAH 0.0005846 0.44182 3.28947
99 2AQJ FAD 0.001784 0.43789 3.28947
100 2AQJ TRP 0.001713 0.43787 3.28947
101 1U1I NAD 0.0005657 0.43504 3.28947
102 3LZW NAP 0.002068 0.43449 3.28947
103 1ZMD NAI 0.0009551 0.43292 3.28947
104 1OBB NAD 0.001563 0.42744 3.28947
105 3LZW FAD 0.001224 0.427 3.28947
106 2EJU SAH 0.0001007 0.41298 3.28947
107 1ORR NAD 0.002695 0.40781 3.28947
108 2B4R AES 0.002148 0.4076 3.28947
109 2B4R NAD 0.002354 0.40746 3.28947
110 3WE0 FAD 0.005933 0.40515 3.28947
111 2YGM GLA NAG GAL FUC 0.03588 0.40254 3.28947
112 2CUL FAD 0.000787 0.43083 3.44828
113 1P1C SAH 0.000005172 0.476 3.51759
114 1R18 SAH 0.00004819 0.43807 3.52423
115 5N53 8NB 0.001738 0.47944 3.58974
116 5KVA SAM 0.0001239 0.42515 3.59712
117 3SQP FAD 0.003424 0.46221 3.61842
118 2HQM FAD 0.0002508 0.45854 3.61842
119 1RSG FAD 0.0006446 0.44235 3.61842
120 4CNK FAD 0.0005767 0.43973 3.61842
121 4PIO SAH 0.000687 0.4318 3.61842
122 1YY5 FAD 0.001428 0.4307 3.61842
123 4PIO AVI 0.0006956 0.43027 3.61842
124 4USR FAD 0.0007596 0.42881 3.61842
125 5DX0 SFG 0.0002427 0.42661 3.61842
126 5DWQ SFG 0.0002604 0.42115 3.61842
127 4AT0 FAD 0.003095 0.42004 3.61842
128 1YBH FAD 0.002023 0.41959 3.61842
129 5MBX FAD 0.004281 0.41924 3.61842
130 5MBX SP5 0.004281 0.41924 3.61842
131 4K5S PM0 0.003546 0.41853 3.61842
132 4K5S FAD 0.00149 0.41764 3.61842
133 5XVQ SAH 0.004079 0.41328 3.61842
134 5M67 NAD 0.005655 0.41035 3.61842
135 5M67 ADE 0.006176 0.40881 3.61842
136 5MQ6 NDP 0.005263 0.40864 3.61842
137 4CQB MLI 0.03877 0.40811 3.61842
138 1UDB NAD 0.007047 0.4081 3.61842
139 5M67 3D1 0.006824 0.40706 3.61842
140 2Q1W NAD 0.001988 0.40047 3.61842
141 5IL1 SAM 0.01387 0.40229 3.66667
142 5FA8 SAM 0.0002703 0.46256 3.72671
143 4J4H 1J1 0.009254 0.40007 3.861
144 4J4H NAI 0.009254 0.40007 3.861
145 1G0N PHH 0.006084 0.40284 3.88693
146 1G0N NDP 0.005781 0.4007 3.88693
147 5FA5 MTA 0.00008722 0.5126 3.94737
148 3AYI HCI 0.0006259 0.4525 3.94737
149 3AYI FAD 0.0005954 0.4525 3.94737
150 3E1T FAD 0.0005609 0.4458 3.94737
151 3NTD FAD 0.00137 0.42509 3.94737
152 4GQB 0XU 0.0002622 0.42262 3.94737
153 5VN0 NAI 0.002837 0.41101 3.94737
154 3V1Y NAD 0.003305 0.40838 3.94737
155 4X60 SFG 0.000202 0.4062 3.94737
156 1J0X NAD 0.005615 0.4061 3.94737
157 4X60 3XV 0.0001876 0.40389 3.94737
158 4B7E OGA 0.04128 0.40319 3.94737
159 1DLJ NAI 0.01049 0.40029 3.94737
160 3ELW GP3 0.001428 0.42869 4
161 3ELW SAM 0.001344 0.42869 4
162 3WV8 ATP 0.0001032 0.41804 4.12844
163 3U31 NAD 0.00648 0.40777 4.13793
164 1KPG SAH 0.003119 0.42132 4.18118
165 2B9W FAD 0.01178 0.40195 4.24528
166 5FJN BE2 0.001363 0.43247 4.27632
167 5FJN FAD 0.001347 0.42969 4.27632
168 5TUK FAD 0.00153 0.41315 4.27632
169 5N5D SAM 0.0001436 0.41183 4.27632
170 1PS9 FAD 0.004641 0.40748 4.27632
171 1ZBQ NAD 0.003179 0.40381 4.28135
172 5ITV NAI 0.00232 0.40769 4.31373
173 3A25 SAM 0.0001681 0.40512 4.31894
174 2WSB NAD 0.003709 0.41031 4.33071
175 4QTU SAM 0.0006111 0.45941 4.44444
176 3FZG SAM 0.008129 0.41977 4.5
177 1IM8 SAI 0.001163 0.44323 4.5082
178 5JJR SAH 0.0007799 0.45887 4.60526
179 3CGD FAD 0.001884 0.44748 4.60526
180 3CGD COA 0.001884 0.44748 4.60526
181 3CGD NAD 0.001884 0.44748 4.60526
182 4FWE FAD 0.0005326 0.44669 4.60526
183 1G55 SAH 0.00154 0.44164 4.60526
184 3GDN HBX 0.002122 0.42925 4.60526
185 3GDN FAD 0.001426 0.42872 4.60526
186 4DSG UDP 0.005011 0.42007 4.60526
187 4EIP FAD 0.002728 0.41951 4.60526
188 4DSG FAD 0.005636 0.41931 4.60526
189 1ELI PYC 0.002083 0.418 4.60526
190 4EIP K2C 0.004811 0.41148 4.60526
191 1VDC FAD 0.005338 0.41052 4.60526
192 4J36 FAD 0.003191 0.405 4.60526
193 4J36 1HR 0.006594 0.40333 4.60526
194 3WJO IPE 0.04331 0.40208 4.60526
195 1Q0S SAH 0.0002451 0.42445 4.6332
196 1N4W FAD 0.0004429 0.44987 4.93421
197 1RYI FAD 0.0006818 0.44031 4.93421
198 1QO8 FAD 0.001193 0.43178 4.93421
199 4EUE NAI 0.001256 0.41915 4.93421
200 3S5W FAD 0.001468 0.41521 4.93421
201 2Q1S NAI 0.003629 0.41363 4.93421
202 5T67 JHZ 0.004196 0.41297 4.93421
203 5T67 SAH 0.003806 0.40987 4.93421
204 1MUU NAD 0.005797 0.40132 4.93421
205 5MW4 5JU 0.0066 0.40047 4.93421
206 1XXR MAN 0.03018 0.41011 4.96894
207 3BGD PM6 0.0004071 0.4278 5
208 3BGD SAH 0.0009273 0.40023 5
209 3DXY SAM 0.000007129 0.42066 5.04587
210 3AD8 NAD 0.0005758 0.43474 5.05051
211 3AD8 FAD 0.004636 0.42482 5.05051
212 5CUQ NSC 0.001713 0.41402 5.24345
213 4NEC SAH 0.001263 0.45792 5.26316
214 1X87 NAD 0.00002903 0.45208 5.26316
215 3QVP FAD 0.0008936 0.43778 5.26316
216 1V5F FAD 0.004754 0.42306 5.26316
217 1YKJ FAD 0.005175 0.42085 5.26316
218 5E72 SAM 0.0002241 0.41839 5.26316
219 1V6A TRE 0.04985 0.40005 5.26316
220 3B9Q MLI 0.02911 0.42245 5.29801
221 5JE8 NAD 0.002104 0.41909 5.29801
222 3QWI CUE 0.003006 0.41492 5.55556
223 1EJ0 SAM 0.0002008 0.40665 5.55556
224 3QWI NAP 0.003649 0.40154 5.55556
225 3VYW SAM 0.0000733 0.49533 5.59211
226 2C7G FAD 0.001111 0.44401 5.59211
227 2C7G ODP 0.00106 0.44401 5.59211
228 1NSA BEN 0.006018 0.42491 5.59211
229 3UOY NAP 0.004892 0.42448 5.59211
230 5EB4 FAD 0.001844 0.42223 5.59211
231 2Q0L NAP 0.007926 0.42029 5.59211
232 3NT6 FAD 0.002608 0.41419 5.59211
233 3QSB 743 0.02961 0.40315 5.59211
234 3VSE SAH 0.00003803 0.40228 5.59211
235 1I1N SAH 0.0003696 0.42881 5.75221
236 5JCM NAD 0.001324 0.4469 5.76497
237 5JCM ISD 0.001324 0.4469 5.76497
238 5JCM FAD 0.001273 0.4469 5.76497
239 4OBW SAM 0.00008864 0.50152 5.83658
240 3A4T SFG 0.0001897 0.42148 5.83942
241 2HNK SAH 0.000359 0.40665 5.85774
242 4BLW AMP 0.000679 0.432 5.88235
243 4BLW SAH 0.0006208 0.41972 5.88235
244 4USQ FAD 0.0005639 0.43509 5.92105
245 3LST SAH 0.006015 0.42984 5.92105
246 3NJ4 NAD 0.02131 0.41509 5.92105
247 3ITJ FAD 0.005991 0.40934 5.92105
248 4RSL FAD 0.0006562 0.40462 5.92105
249 4XFR CIT 0.03996 0.4036 5.92105
250 1JG3 ADN 0.000006057 0.55414 5.95745
251 1I7M CG 0.01888 0.41714 5.97015
252 4G74 FAD 0.0007913 0.4002 5.9761
253 2VDV SAM 0.0000972 0.51614 6.09756
254 4D79 ATP 0.00111 0.45193 6.15942
255 1KYQ NAD 0.0002004 0.40471 6.20438
256 3DMH SAM 0.0001714 0.47932 6.25
257 1REO FAD 0.0003402 0.44987 6.25
258 3DMH GMP 0.0002825 0.44727 6.25
259 3CGB FAD 0.0005572 0.43911 6.25
260 3GD4 NAD 0.003351 0.43508 6.25
261 3GD4 FAD 0.002459 0.4314 6.25
262 5MPT SAH 0.003415 0.42988 6.25
263 2VVM FAD 0.00157 0.42497 6.25
264 3TKA SAM 0.0003922 0.4052 6.25
265 2PZM UDP 0.006371 0.40392 6.25
266 2PZM NAD 0.006371 0.40392 6.25
267 3OJO NAD 0.0007547 0.40246 6.25
268 4K28 NAD 0.007105 0.40041 6.3197
269 3GEG NAD 0.001244 0.41026 6.47773
270 1JNR FAD 0.001408 0.45106 6.57895
271 2CDU FAD 0.0003342 0.44645 6.57895
272 1H82 GZZ 0.001307 0.44497 6.57895
273 1H82 FAD 0.001466 0.43987 6.57895
274 2BRY FAD 0.0008676 0.4266 6.57895
275 3IHG FAD 0.0009246 0.41807 6.57895
276 3NDJ JHZ 0.003302 0.41803 6.57895
277 3NDJ SAH 0.003302 0.41803 6.57895
278 4TXI FAD 0.0008435 0.41337 6.57895
279 2C31 TZD 0.01705 0.40392 6.57895
280 2C31 ADP 0.01654 0.40392 6.57895
281 5ULP KB1 0.0003393 0.45467 6.71642
282 5BW4 SAM 0.0001215 0.4048 6.74157
283 1ZEM NAD 0.001015 0.41062 6.87023
284 3LAD FAD 0.0003921 0.45088 6.90789
285 2B99 RDL 0.02863 0.40034 7.05128
286 5C9J DAO 0.02371 0.40808 7.07071
287 1R6D NAD 0.01151 0.40092 7.23684
288 1U7T TDT 0.005863 0.40347 7.27969
289 3OFK SAH 0.001175 0.43939 7.40741
290 4M73 M72 0.0001169 0.46543 7.56579
291 4M73 SAH 0.0001769 0.45713 7.56579
292 4UP3 FAD 0.006212 0.4015 7.56579
293 1WY7 SAH 0.0003704 0.40538 7.72947
294 1Y8Q ATP 0.0001137 0.47414 7.89474
295 1GET NAP 0.00085 0.45704 7.89474
296 1GET FAD 0.0008209 0.45628 7.89474
297 3T31 DCQ 0.001006 0.44659 7.89474
298 3T31 FAD 0.0009171 0.44659 7.89474
299 5UAV TFB 0.004798 0.40058 7.89474
300 1GY8 NAD 0.003639 0.4003 7.89474
301 5UAV NDP 0.004609 0.40009 7.89474
302 4YMH SAH 0.0003034 0.46855 7.91667
303 2OBF F83 0.001982 0.42306 7.95848
304 3A27 SAM 0.000097 0.49975 8.08823
305 2PWY SAH 0.00006667 0.43611 8.13953
306 1V59 FAD 0.0002442 0.46227 8.159
307 1V59 NAD 0.00001334 0.4144 8.159
308 1UWK NAD 0.0001158 0.4752 8.22368
309 1UWK URO 0.0001158 0.4752 8.22368
310 3L9W GSH 0.0001842 0.44352 8.22368
311 3L9W AMP 0.000262 0.44352 8.22368
312 2WET FAD 0.000431 0.44815 8.55263
313 3F8D FAD 0.004284 0.42876 8.55263
314 1D4D FAD 0.001583 0.42793 8.55263
315 3GRU AMP 0.00006241 0.44069 8.81356
316 4HSU FAD 0.0004319 0.45136 8.87097
317 4GUT FAD 0.0006567 0.44612 8.87097
318 4GUS FAD 0.0007236 0.44244 8.87097
319 4Y2H SAH 0.0006275 0.43947 8.88158
320 4Y2H 49K 0.000735 0.43679 8.88158
321 1VQW FAD 0.001705 0.4154 8.88158
322 2GVC FAD 0.001716 0.41529 8.88158
323 2DPM SAM 0.0002087 0.41942 9.15493
324 5E8J SAH 0.0009642 0.46817 9.21053
325 3CTY FAD 0.00456 0.41062 9.21053
326 1XDS SAM 0.0005314 0.48063 9.35829
327 1E6E FAD 0.001705 0.41909 9.375
328 1QAN SAH 0.0003992 0.40692 9.42623
329 4WEY EG6 0.009113 0.41057 9.52381
330 4BV6 FAD 0.0008326 0.43689 9.53947
331 1N2X SAM 0.001556 0.40086 9.63455
332 4M38 SAH 0.0001345 0.48389 9.86842
333 4AP3 NAP 0.0008088 0.45285 9.86842
334 1DL5 SAH 0.0001685 0.43591 9.86842
335 4TM3 FAD 0.00422 0.4278 9.86842
336 2DKH 3HB 0.001847 0.42113 9.86842
337 2DKH FAD 0.001248 0.42058 9.86842
338 4M37 SAH 0.000112 0.42031 9.86842
339 4D7E FAD 0.000625 0.40623 9.86842
340 2FK8 SAM 0.002478 0.42896 10.1974
341 1UP7 NAD 0.0004975 0.41788 10.1974
342 3SHR CMP 0.02301 0.40875 10.3679
343 5E1M SAH 0.001193 0.44274 10.3734
344 3HVJ 705 0.000267 0.4515 10.4072
345 4REP FAD 0.0009781 0.43193 10.5263
346 5JE0 AZ8 0.001741 0.4068 10.5263
347 5JE0 SAH 0.001741 0.4068 10.5263
348 3G2O SAM 0.0001606 0.48986 10.7023
349 3G89 SAM 0.00002933 0.54119 10.8434
350 4EMI NAD 0.00264 0.4316 10.8553
351 5THY SAH 0.002429 0.42933 10.8553
352 4EMI FAD 0.001291 0.42609 10.8553
353 2Z3Y F2N 0.00232 0.42135 10.8553
354 1SQF SAM 0.00007689 0.42115 10.8553
355 2Y6Q I7T 0.004988 0.41085 10.8553
356 2Y6Q FAD 0.00219 0.40997 10.8553
357 4EMJ FAD 0.001503 0.42464 11.215
358 3EGV SAH 0.000117 0.5012 11.4173
359 2NXE SAM 0.0002923 0.47811 11.4173
360 5DLY SAH 0.0002266 0.41188 11.6541
361 5DLY 5D7 0.0002328 0.40408 11.6541
362 2RAB NAD 0.0007115 0.45888 11.8421
363 2RAB FAD 0.0002836 0.45862 11.8421
364 4YNU LGC 0.0005455 0.45128 11.8421
365 4YNU FAD 0.0008852 0.43896 11.8421
366 2XVE FAD 0.003857 0.42478 11.8421
367 2XVF FAD 0.001602 0.42131 11.8421
368 1TDF NAP 0.01498 0.40575 11.8421
369 1TDF FAD 0.008815 0.40092 11.8421
370 1RP0 AHZ 0.0003563 0.43994 11.9718
371 4FZV SAM 0.00004781 0.43503 12.1339
372 5L95 AMP 0.001477 0.44244 12.5
373 1FEC FAD 0.001409 0.43285 12.5
374 1FL2 FAD 0.001815 0.42143 12.5
375 3FPF MTA 0.0001145 0.46836 12.7517
376 3FPF TNA 0.0001145 0.41348 12.7517
377 3M6W SAM 0.009059 0.41754 12.8289
378 1VKO NAD 0.001999 0.40067 13.1579
379 4N49 SAM 0.0004338 0.40594 13.3178
380 2E5V FAD 0.002329 0.42128 13.4868
381 1ZQ9 SAM 0.00001041 0.44664 13.6842
382 1LVL NAD 0.0000694 0.49636 13.9738
383 2WPF FAD 0.001778 0.45561 14.1447
384 2WPF WPF 0.002212 0.45293 14.1447
385 5MGZ SAH 0.001527 0.4418 14.4068
386 2JJQ SAH 0.0002224 0.49884 14.8026
387 2HMT NAI 0.0004107 0.40844 15.2778
388 1QD0 RR6 0.0106 0.42179 15.625
389 1NV8 MEQ 0.0001186 0.44763 15.8451
390 1NV8 SAM 0.0001491 0.44763 15.8451
391 5XVK SAH 0.003019 0.41875 15.8451
392 3MB5 SAM 0.0003426 0.41508 16.4706
393 4XUC 43G 0.0007387 0.4306 16.9725
394 4XUC SAM 0.0007387 0.4306 16.9725
395 1X7D ORN 0.003794 0.40676 18.0921
396 3WGT QSC 0.002129 0.42746 18.4211
397 3WGT FAD 0.002886 0.42127 18.4211
398 3ZNN 4WL 0.00435 0.42046 18.4211
399 3ZNN FAD 0.00435 0.42046 18.4211
400 2F5Z FAD 0.0001995 0.4636 18.75
401 5TVF CGQ 0.02586 0.40255 18.8235
402 1LSS NAD 0.00004903 0.43365 20
403 5LOG SAH 0.0001623 0.41169 21.03
404 1L3I SAH 0.000155 0.438 21.875
405 3CBG SAH 0.0001062 0.40677 21.9828
406 2GAG NAD 0.0007454 0.43421 23.2323
407 2GAG FAD 0.001848 0.4272 23.2323
408 2GAG FOA 0.001886 0.42684 23.2323
409 4J56 FAD 0.001656 0.42814 26.3158
410 3C6K SPD 0.000000000144 0.69243 30.5921
411 3C6K MTA 0.000000000144 0.69243 30.5921
412 5DXA SFG 0.0006226 0.44742 31.5789
413 5DX8 SFG 0.0007399 0.44428 31.5789
414 5DX1 SFG 0.0007277 0.40971 31.5789
Pocket No.: 4; Query (leader) PDB : 2O07; Ligand: MTA; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2o07.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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