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Receptor
PDB id Resolution Class Description Source Keywords
3REF 1.95 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF EHRHO1 BOUND TO GDP AND MAGNESIUM ENTAMOEBA HISTOLYTICA CYTOSKELETON NUCLEOTIDE-BINDING GTP-BINDING SIGNALING PROLIPOPROTEIN PRENYLATION
Ref.: UNIQUE STRUCTURAL AND NUCLEOTIDE EXCHANGE FEATURES RHO1 GTPASE OF ENTAMOEBA HISTOLYTICA. J.BIOL.CHEM. V. 286 39236 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:274;
B:274;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:192;
B:550;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
SO4 A:193;
A:194;
B:192;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3REF 1.95 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF EHRHO1 BOUND TO GDP AND MAGNESIUM ENTAMOEBA HISTOLYTICA CYTOSKELETON NUCLEOTIDE-BINDING GTP-BINDING SIGNALING PROLIPOPROTEIN PRENYLATION
Ref.: UNIQUE STRUCTURAL AND NUCLEOTIDE EXCHANGE FEATURES RHO1 GTPASE OF ENTAMOEBA HISTOLYTICA. J.BIOL.CHEM. V. 286 39236 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 3REF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 3REF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 2W2T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3REF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2J0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3REF; Ligand: GDP; Similar sites found with APoc: 578
This union binding pocket(no: 1) in the query (biounit: 3ref.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1LVG ADP None
2 5BQ5 ADP BEF None
3 4QM7 GTP None
4 3L6C MLI 1.03093
5 3VZS NAP 1.03093
6 5GVR LMR 1.54639
7 2ZPA ADP 1.54639
8 4BFW ZVW 1.54639
9 1AKY AP5 1.54639
10 4ZNL BEF ADP 1.54639
11 3HQ9 OXL 1.54639
12 1DCP HBI 1.92308
13 1DAK ADP 2.06186
14 1DAK DPU 2.06186
15 3DKP ADP 2.06186
16 3FB4 AP5 2.06186
17 3W5J GDP 2.06186
18 3GFS FMN 2.29885
19 1XPJ TLA 2.38095
20 3E70 GDP 2.57732
21 1JJV ATP 2.57732
22 2OFW ADX 2.57732
23 5J1J ANP 2.57732
24 1X6V ADP 2.57732
25 2QZ4 ADP 2.57732
26 1XMV ADP 2.57732
27 1JI0 ATP 2.57732
28 3BFV ADP 2.57732
29 5DT6 GLU 2.57732
30 2PEZ DAT 2.7933
31 2PEZ GGZ 2.7933
32 4R98 GNH 3.09278
33 1Z6T ADP 3.09278
34 3DC4 ADP 3.09278
35 1ZIN AP5 3.09278
36 2D7D ADP 3.09278
37 4MKG AP5 3.09278
38 4E03 ADP 3.09278
39 1NHX FTB 3.09278
40 1NHX PEP 3.09278
41 1T5C ADP 3.09278
42 5G3Y ADP 3.09278
43 3BOS CDP 3.09278
44 1NY5 ADP 3.09278
45 3ITJ CIT 3.09278
46 2GMV UN8 3.09278
47 2GMV PEP 3.09278
48 1W5T ANP 3.09278
49 1W5T ADP 3.09278
50 4WOP CTP 3.11111
51 4J0Q GDP 3.60825
52 5W76 GDP 3.60825
53 2XT3 ADP 3.60825
54 1V8K ANP 3.60825
55 1D2E GDP 3.60825
56 4LPS GDP 3.60825
57 3TK1 GDP 3.60825
58 5LTJ BEF 3.60825
59 2ZFI ADP 3.60825
60 2GK6 ADP 3.60825
61 3IO3 ADP 3.60825
62 2VVG ADP 3.60825
63 2FAH GDP 3.60825
64 5G41 AP5 3.60825
65 5E5U MLI 3.60825
66 6A20 ADP 3.60825
67 1VKJ A3P 3.60825
68 2O0J ADP 3.60825
69 5LTJ ADP 3.60825
70 1G0N PHH 3.60825
71 1G0N NDP 3.60825
72 1UKZ ADP 3.60825
73 3EWA ANP 3.60825
74 2IS6 ADP 3.60825
75 1JJ7 ADP 3.60825
76 4YAG NAI 3.60825
77 1Z83 AP5 3.60825
78 2VOH CIT 3.82166
79 2IL4 COA 3.8835
80 5W75 GDP 4.12371
81 3COB ADP 4.12371
82 1BH2 GSP 4.12371
83 1TQ4 GDP 4.12371
84 5HCN GCP 4.12371
85 1Y3A GDP 4.12371
86 5I0H ADP BEF 4.12371
87 2OM2 GDP 4.12371
88 1SVK ALF GDP 4.12371
89 4IHQ ADP 4.12371
90 4ZG4 VO4 ADP 4.12371
91 2OBM ADP 4.12371
92 1U0J ADP 4.12371
93 4XGU ADP 4.12371
94 5IFS ADP 4.12371
95 2Q2Y ADP 4.12371
96 2Q2Y MKR 4.12371
97 1FNN ADP 4.12371
98 4LYA ATP 4.12371
99 3UIE ANP 4.12371
100 1OYY AGS 4.12371
101 1YTM ATP 4.12371
102 4X8O AP5 4.12371
103 1BG2 ADP 4.12371
104 4D81 ADP 4.12371
105 3R7F CP 4.12371
106 5VGR GDP 4.12371
107 5ZB0 ADP 4.12371
108 5ZB0 TYD 4.12371
109 5H68 AGS 4.12371
110 3QXC ATP 4.12371
111 1G3Q ADP 4.12371
112 2XAU ADP 4.12371
113 3S5W FAD 4.12371
114 2YOH WMJ 4.12371
115 4NBU NAI 4.12371
116 5THQ NDP 4.41176
117 1B7T ADP 4.48718
118 1B0U ATP 4.58015
119 3KTA AP5 4.62428
120 4DCT GDP 4.63918
121 2Y65 ADP 4.63918
122 5U32 GDP 4.63918
123 4B47 GDP 4.63918
124 5AK0 8V1 4.63918
125 2BIF SIN 4.63918
126 2BIF ANP 4.63918
127 1NJF ADP 4.63918
128 2IYL GDP 4.63918
129 1LVK MNT BEF 4.63918
130 3IUY AMP 4.63918
131 1NJF AGS 4.63918
132 1T8U UAP SGN IDS SGN 4.63918
133 1SVM ATP 4.63918
134 1VHT BA3 4.63918
135 4V03 ADP 4.63918
136 4FRZ ADP 4.63918
137 1OS1 PYR 4.63918
138 4MKF AP5 4.63918
139 2ZJ5 ADP 4.63918
140 1OS1 ATP 4.63918
141 4YDS ATP 4.63918
142 5ZXD ATP 4.63918
143 6AIC AMP 4.63918
144 5NM7 GLY 4.63918
145 4GBM A3P 4.63918
146 4QOS ADP 4.63918
147 6FAA ADP 4.63918
148 3FSY SCA 4.63918
149 1G6H ADP 4.63918
150 1QF9 ALF 4.63918
151 1QF9 ADP 4.63918
152 1QF9 C5P 4.63918
153 4Z7X 3CX 4.63918
154 1RRC ADP 4.63918
155 5Z2L NDP 4.63918
156 3L6R MLI 4.63918
157 1XEX ATP 4.65116
158 1APZ ASP 4.93827
159 2C78 GNP 5.15464
160 2C77 GNP 5.15464
161 5GOE GDP 5.15464
162 4R2I ANP 5.15464
163 2PL3 ADP 5.15464
164 3FKQ ATP 5.15464
165 4JLV ADP 5.15464
166 2FNA ADP 5.15464
167 2BEK ATP 5.15464
168 5FHD ADP ALF 5.15464
169 3RLF ANP 5.15464
170 1G41 ADP 5.15464
171 2AWN ADP 5.15464
172 2CBZ ATP 5.15464
173 5FTB ANP 5.15464
174 1D2N ANP 5.15464
175 4PPF FLC 5.15464
176 1RJW ETF 5.15464
177 1ZUI SKM 5.35714
178 2QQ0 ANP 5.43478
179 2QQ0 TMP 5.43478
180 2QQ0 ADP 5.43478
181 2QQ0 THM 5.43478
182 3ZQ6 ADP ALF 5.55556
183 5MVR ADP 5.55556
184 3U6B GDP 5.6701
185 2BVN GNP 5.6701
186 1KK1 GNP 5.6701
187 1WDT GTP 5.6701
188 2HCJ GDP 5.6701
189 5W7Q GDP 5.6701
190 5JBQ GDP 5.6701
191 1D8T GDP 5.6701
192 3U6K GDP 5.6701
193 4G5G GDP 5.6701
194 4P3Y GDP 5.6701
195 3B5J 12D 5.6701
196 3CNL GNP 5.6701
197 4KVA GTP 5.6701
198 5LB3 ADP 5.6701
199 2CE7 ADP 5.6701
200 2ZTS ADP 5.6701
201 4IDN GNP 5.6701
202 1UJ2 ADP 5.6701
203 1UJ2 C5P 5.6701
204 4RZ3 ADP 5.6701
205 1M2Z BOG 5.6701
206 4ZDJ UTP 5.6701
207 3QKT ANP 5.6701
208 1NN5 ANP 5.6701
209 1NN5 2DT 5.6701
210 3EZ2 ADP 5.6701
211 4A4Z ANP 5.6701
212 1RM0 NAI 5.6701
213 4NFE BEN 5.6701
214 4YJ1 ADP 5.6701
215 4NTO 1PW 5.6701
216 1NRJ GTP 5.6962
217 3H86 AP5 5.72917
218 4NCN GTP 6.18557
219 3VMF GTP 6.18557
220 3CX8 GSP 6.18557
221 2QN6 GDP 6.18557
222 3WYA GDP 6.18557
223 3WY9 GDP 6.18557
224 2WIC GNP 6.18557
225 3KJI ADP 6.18557
226 5L3W GDP 6.18557
227 6CS8 F9Y 6.18557
228 3FVQ ATP 6.18557
229 3TMK T5A 6.18557
230 2GKS ADP 6.18557
231 3FYH ADP 6.18557
232 3B7G ANP 6.18557
233 4D42 W0I 6.18557
234 4D42 NAP 6.18557
235 1W4R TTP 6.18557
236 5BYK OAQ 6.18557
237 5BYK A3P 6.18557
238 5X40 ACP 6.50685
239 4UXH T5A 6.52174
240 1BO4 COA 6.54762
241 4RD0 GDP 6.70103
242 5XKT GNP 6.70103
243 5BN3 ADP 6.70103
244 1IWE IMP 6.70103
245 4OHY ANP 6.70103
246 5H7J GCP 6.70103
247 1IHU AF3 6.70103
248 1IHU ADP 6.70103
249 4NU0 AP5 6.70103
250 3LRE ADP 6.70103
251 1ION ADP 6.70103
252 5Z69 AGS 6.70103
253 1NST A3P 6.70103
254 1M2O GNP 6.84211
255 5H67 ATP 6.91489
256 4OI4 ATP 6.95652
257 4ZKD GDP 7.2165
258 4PC3 GDP 7.2165
259 1DAR GDP 7.2165
260 2HF9 GSP 7.2165
261 1R0X ATP 7.2165
262 3Q9L ATP 7.2165
263 5VHC BEF ADP 7.2165
264 1S3G AP5 7.2165
265 1XKV ATP 7.2165
266 2VTD LKM 7.2165
267 4YMU ATP 7.2165
268 2DPY ADP 7.2165
269 2CDN ADP 7.2165
270 4IOK ADP 7.2165
271 4IOK XPO 7.2165
272 3CV2 OXL 7.2165
273 3IIJ ADP 7.22222
274 1F2U ATP 7.38255
275 6C90 ADP 7.69231
276 2RCN GDP 7.73196
277 4WZ6 ATP 7.73196
278 2WHX ADP 7.73196
279 4P4T GDP 7.73196
280 1M7G AV2 7.73196
281 4WZA ADP 7.73196
282 1RJ9 GCP 7.73196
283 4WZA ACP 7.73196
284 5M04 GDP 7.73196
285 2CHG ANP 7.73196
286 3ZFD ANP 7.73196
287 4FCW ADP 7.73196
288 5MZN ADP 7.73196
289 1M7G ADX 7.73196
290 1M7G ADP 7.73196
291 4LJ9 ACP 7.73196
292 2JLR ANP 7.73196
293 1FP6 ADP 7.73196
294 1U1I NAD 7.73196
295 4PJ3 ANP 7.73196
296 3P4X ADP 7.74818
297 2QTV GNP 7.78443
298 6CRK GDP 8.11594
299 5J1S ATP 8.13008
300 3H4S ADP 8.14815
301 5KDO GDP 8.23529
302 4U00 ADP 8.24742
303 5ZBR ANP 8.24742
304 5Y6N ADP 8.24742
305 6B4K ANP 8.24742
306 2QG6 NMN 8.24742
307 1PUJ GNP 8.76289
308 4IEE AGS 8.76289
309 5L3S GNP 8.76289
310 5L3V GDP 8.76289
311 1QF5 RPL 8.76289
312 1QF5 GDP 8.76289
313 4HSE ADP 8.76289
314 4WEI GLC GAL 8.76289
315 5XDR ADP 8.76289
316 5L3S G 8.76289
317 1HTW ADP 8.86076
318 2KIN ADP 9
319 1F6B GDP 9.27835
320 5WC2 ADP 9.27835
321 1E2K TMC 9.27835
322 4NE2 SH2 9.27835
323 4NE2 ADP 9.27835
324 1SQ5 ADP 9.27835
325 3BER AMP 9.27835
326 2C9O ADP 9.27835
327 1OXV ANP 9.27835
328 6B8B ADP 9.27835
329 1XP8 AGS 9.27835
330 2GWH A3P 9.27835
331 1P9B GDP 9.27835
332 6AU6 GDP 9.79381
333 1CS4 GSP 9.79381
334 5TSH ADP 9.79381
335 3AB3 GDP 9.79381
336 5TSH ANP 9.79381
337 1ZCB GDP 9.79381
338 1W0J ADP 9.79381
339 1W0J ADP BEF 9.79381
340 4QRH 0O2 9.79381
341 3PQC GDP 10.3093
342 4DDY DN6 10.3093
343 5K5Z ANP 10.3093
344 1F5N GNP 10.3093
345 2FSH ANP 10.3093
346 4Q1A UDP 10.3093
347 4Q1A 2XZ 10.3093
348 2NCD ADP 10.3093
349 5I34 GDP 10.3093
350 5N69 ADP 10.3093
351 2X7I CIT 10.3093
352 3NHB ADP 10.3093
353 1W7J ADP BEF 10.596
354 1G7C 5GP 10.6383
355 2ODE ALF GDP 10.6383
356 5IRN ADP 10.8247
357 1IN4 ADP 10.8247
358 2J5V PCA 10.8247
359 4R43 GDP 10.8247
360 4GOX A3P 10.8247
361 5UIV ADP 10.8247
362 1KO8 6PG 10.8571
363 4H1V GNP 11.3402
364 4PX9 ADP 11.3402
365 4TL6 ANP 11.3402
366 5HR5 ADP 11.3402
367 4CVN ADP 11.6788
368 1SKQ GDP 11.8557
369 4TMZ GSP 11.8557
370 5H7K GDP 11.8557
371 2OZE AGS 11.8557
372 3RC3 ANP 11.8557
373 1K6M AGS 11.8557
374 2ZR9 DTP 11.8557
375 1L2T ATP 11.8557
376 5M7P ADP 11.8557
377 5TIV A3P 11.8557
378 1FQJ ALF 11.9048
379 1FQJ GDP 11.9048
380 2V7Q ATP 12
381 2CK3 ANP 12
382 2CK3 ADP 12
383 2V7Q ADP 12
384 3QF7 ANP 12
385 3T34 GDP 12.3711
386 3DZD ADP 12.3711
387 4DBH OXL 12.3711
388 1Q19 SSC 12.3711
389 1XX6 ADP 12.5654
390 2PZE ATP 12.8866
391 3TBK ANP 12.8866
392 2W58 ADP 13.4021
393 3WXM GTP 13.4021
394 5EXT ADP 13.4021
395 5MEX PAP 13.4021
396 1KK8 BEF ADP 14.2857
397 4M9Q GNP 14.433
398 2XTZ GSP 14.433
399 3ZIA ADP 14.433
400 1H65 GDP 14.433
401 3DEF GDP 14.433
402 3ZIA ATP 14.433
403 4YS0 ADP 14.433
404 4NON GDP 14.9485
405 2RGX AP5 14.9485
406 1GXU 2HP 15.3846
407 1ZD9 GDP 15.4255
408 2WJG GDP 15.4255
409 1Y4Z PCI 15.4639
410 3K5I AIR 15.4639
411 5CK5 GDP 15.9794
412 1P72 ADP 15.9794
413 1G8S MET 15.9794
414 1YRB GDP 16.4948
415 1Y63 ADP 16.8478
416 2OG2 MLI 17.0103
417 1G7S GDP 17.0103
418 3B9Q MLI 17.0103
419 4HI0 GDP 17.0103
420 5L3R GCP 17.0103
421 4TTQ ATP 17.0103
422 2WJH GDP 17.4699
423 2WJH FLC 17.4699
424 1MKY GDP 18.0412
425 1OFH ADP 18.3908
426 5IRR GSP 18.5567
427 1GOJ ADP 18.5567
428 3BFX A3P 18.5567
429 4BQS K2Q 18.75
430 4BQS ADP 18.75
431 5DI3 GNP 18.9189
432 4V0K GDP 18.9349
433 1CR1 TTP 19.0722
434 3DOE GTP 19.7917
435 1KSH GDP 19.8925
436 5YT0 GDP 20.1031
437 5FG3 GDP 20.1031
438 1F9V ADP 20.1031
439 3A4M ADP 20.3846
440 2FH5 GTP 20.6186
441 3T12 GDP ALF 20.6186
442 3T1O GDP 20.6186
443 1ZJ6 G3D 20.8556
444 1YZG GDP 21.229
445 3FWY ADP 22.1649
446 1UPT GTP 22.2222
447 2X77 GDP 22.2222
448 5KSZ GCP 22.6804
449 5EE5 GTP 22.807
450 3PCR GTP 22.8395
451 5KSP GDP 23.1579
452 2A5F GTP 23.4286
453 1J2J GTP 23.494
454 2J59 GTP 23.494
455 1O3Y GTP 23.494
456 1RE0 GDP 23.7805
457 1S9D GDP 23.7805
458 3N5C GDP 24.0741
459 4PFO ADP 24.2268
460 1R4A GNP 24.2424
461 4ZI2 GNP 24.7368
462 2WOJ ADP ALF 24.7423
463 3ZS9 ADP ALF 24.7423
464 4XTR ATP 24.7423
465 4XVU ATP 24.7423
466 4XTR ADP 24.7423
467 4GOJ GNP 24.8677
468 4KAX GTP 25.4438
469 2W83 GTP 25.4545
470 3AQ4 GDP 25.5435
471 1FZQ GDP 25.9669
472 2VB6 ADP BEF 26.2887
473 5KUT GDP 26.9841
474 1MR3 G3D 27.0718
475 4YLG GDP 28.9017
476 2ZEJ GDP 29.3478
477 4BAS GNP 29.8969
478 3WYF GTP 30.4124
479 3M1I GTP 30.4124
480 3GJX GTP 30.4124
481 3GJ7 GDP 30.9278
482 5DIF GNP 30.9278
483 5UWW GNP 30.9278
484 5UWP GNP 30.9278
485 5UWU GNP 30.9278
486 5UWI GNP 30.9278
487 3GJ4 GDP 30.9278
488 5UWQ GNP 30.9278
489 5UWJ GNP 30.9278
490 5UWO GNP 30.9278
491 5UWR GNP 30.9278
492 5UWS GNP 30.9278
493 6CIT GNP 30.9278
494 4HAT GNP 30.9278
495 5DHF GNP 30.9278
496 5UWH GNP 30.9278
497 5UWT GNP 30.9278
498 3GJ5 GDP 30.9278
499 5DI9 GNP 30.9278
500 3GJ8 GDP 30.9278
501 3CH5 GDP 30.9278
502 3GJ3 GDP 30.9278
503 3T5G GDP 31.4917
504 3WYG GTP 32.4176
505 3RWO GDP 32.4324
506 2BCG GDP 32.4742
507 3E5H GNP 33.1461
508 1YZN GNP 34.0541
509 1WA5 GTP 34.0909
510 1Z06 GNP 34.3915
511 3A1S GDP 34.5361
512 1VG8 GNP 36.5979
513 1VG0 GDP 36.5979
514 2BME GNP 38.172
515 2CJW GDP 38.5417
516 1VG1 GDP 38.9189
517 1VG9 GDP 38.9189
518 5Z2M GTP 40.3409
519 1Z0K GTP 40.6977
520 2HT6 GDP 40.8046
521 3Q72 GNP 40.9639
522 3TKL GTP 41.2371
523 5SZH GNP 41.7526
524 1OIX GDP 41.8848
525 2EFE GNH 41.9889
526 3BC1 GNP 42.268
527 2F9L GDP 42.268
528 3CPJ GDP 42.268
529 1OIV GDP 42.4084
530 1ZC3 GNP 42.8571
531 1UAD GNP 43.4286
532 3SFV GDP 43.6464
533 2EW1 GNP 43.7811
534 5TB5 GDP 43.7838
535 5TAR GDP 43.7838
536 5OCG GNP 43.8144
537 2A9K GDP 43.8503
538 1TU3 GNP 43.8596
539 5LEF GTP 43.9791
540 3MJH GTP 44.0476
541 1R2Q GNP 44.1176
542 5OEC GDP 44.2623
543 4DKX GDP 44.3299
544 3Q85 GNP 44.3787
545 5UQW GDP 44.4444
546 1U8Z GDP 44.6429
547 5O74 GDP 45
548 5JCZ GDP 45.2514
549 2A5J GDP 45.5497
550 4LX0 BEF GDP 45.7627
551 2C5L GTP 46.2428
552 3NKV GNP 46.2857
553 1Z0J GTP 46.4706
554 4K81 GTP 46.7836
555 4C4P GNP 46.8208
556 2Y8E GNP 46.9274
557 3QBT GNP 47.1264
558 4LHW GNP 47.1264
559 3TNF GNP 47.1264
560 1KY3 GDP 47.2527
561 1YVD GNP 47.3373
562 5O2T GSP 47.3373
563 2FFQ GSP 47.3684
564 1EK0 GNP 47.6471
565 1YZQ GNP 47.6471
566 1Z0A GDP 47.7011
567 1X1R GDP 47.7528
568 5WDR GNP 47.9532
569 1CLU DBG 48.1928
570 2UZI GTP 48.1928
571 5E95 GDP 48.2143
572 1GWN GTP 48.4536
573 3DDC GNP 48.7952
574 3KUD GDP 48.7952
575 1Z0F GDP 49.162
576 1Z08 GNP 49.4118
577 4D0G GTP 49.7143
578 1S8F GDP 49.7175
579 1M7B GTP 50
580 6BSX GDP 50
581 6BSX E7S 50
Pocket No.: 2; Query (leader) PDB : 3REF; Ligand: GDP; Similar sites found with APoc: 8
This union binding pocket(no: 2) in the query (biounit: 3ref.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1EXF GLY None
2 3QVV A3P 3.60825
3 2TOH HBI 4.63918
4 4IF4 BEF 5.15464
5 5WRJ A3P 5.6701
6 2WPB ZZI 7.2165
7 2V2G BEZ 11.3402
8 1GJW GLC 13.4021
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