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Receptor
PDB id Resolution Class Description Source Keywords
3QPB 1.82 Å EC: 2.4.2.3 CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES URIDINE PHOSPHOR REVEALS A SUBCLASS OF THE NP-I SUPERFAMILY STREPTOCOCCUS PYOGENES SEROTYPE M6 HEXAMER NP-I SUPERFAMILY PYRIMIDINE SALVAGE PATHWAY URIDIPHOSPHORYLASE TRANSITION STATE TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES URI PHOSPHORYLASE REVEALS A DISTINCT SUBFAMILY OF NUCLE PHOSPHORYLASES. BIOCHEMISTRY V. 50 6549 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
R1P A:1254;
B:1254;
C:1254;
D:1254;
E:1254;
F:1254;
G:1254;
H:1254;
I:1254;
J:1254;
K:1254;
L:1254;
M:1254;
N:1254;
O:1254;
P:1254;
Q:1254;
R:1254;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
230.11 C5 H11 O8 P C([C@...
URA A:1255;
B:1255;
C:1255;
D:1255;
E:1255;
F:1255;
G:1255;
H:1255;
I:1255;
J:1255;
K:1255;
L:1255;
M:1255;
N:1255;
O:1255;
P:1255;
Q:1255;
R:1255;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
112.087 C4 H4 N2 O2 C1=CN...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3QPB 1.82 Å EC: 2.4.2.3 CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES URIDINE PHOSPHOR REVEALS A SUBCLASS OF THE NP-I SUPERFAMILY STREPTOCOCCUS PYOGENES SEROTYPE M6 HEXAMER NP-I SUPERFAMILY PYRIMIDINE SALVAGE PATHWAY URIDIPHOSPHORYLASE TRANSITION STATE TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES URI PHOSPHORYLASE REVEALS A DISTINCT SUBFAMILY OF NUCLE PHOSPHORYLASES. BIOCHEMISTRY V. 50 6549 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 3QPB - URA C4 H4 N2 O2 C1=CNC(=O)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3QPB - URA C4 H4 N2 O2 C1=CNC(=O)....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3QPB - URA C4 H4 N2 O2 C1=CNC(=O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: R1P; Similar ligands found: 25
No: Ligand ECFP6 Tc MDL keys Tc
1 R1P 1 1
2 M1P 0.852941 0.904762
3 XGP 0.852941 0.904762
4 G1P 0.852941 0.904762
5 GL1 0.852941 0.904762
6 RI2 0.609756 0.926829
7 GFP 0.571429 0.826087
8 GP1 0.571429 0.76
9 NG1 0.48 0.690909
10 GN1 0.48 0.690909
11 ALX 0.465116 0.904762
12 BNX 0.465116 0.904762
13 TRE 0.45 0.622222
14 T6P 0.44 0.844444
15 AMG 0.439024 0.6
16 GYP 0.439024 0.6
17 MBG 0.439024 0.6
18 MMA 0.439024 0.6
19 G16 0.4375 0.840909
20 YO5 0.418605 0.8
21 GPM 0.418605 0.8
22 MVP 0.418182 0.808511
23 PRP 0.411765 0.951219
24 PPC 0.411765 0.886364
25 GMB 0.403846 0.840909
Ligand no: 2; Ligand: URA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 URA 1 1
2 TUL 0.5 0.725
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 306
This union binding pocket(no: 1) in the query (biounit: 3qpb.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5LOG SAH 0.858369
2 2ZFU SAH 0.930233
3 1H5R THM 1.06383
4 1H5S TMP 1.06383
5 1H5T DAU 1.06383
6 1IIM TTP 1.06383
7 3P8N L4T 1.07527
8 5FA8 SAM 1.24224
9 2JLD ALA GLY GLY ALA ALA ALA ALA ALA 1.41844
10 1PA9 CSN 1.41844
11 6FA4 D1W 1.7341
12 1Z3C SA8 1.77305
13 3H8V ATP 1.77305
14 4R74 F6P 1.77305
15 3SSO SAH 1.77305
16 5DX0 SFG 1.77305
17 5AHS COA 1.77305
18 5DXA SFG 1.77305
19 6BHV DQV 1.84502
20 2RDE C2E 1.99203
21 4CE5 PDG 2.12766
22 1IYE PGU 2.12766
23 6BQC LOP 2.12766
24 1UMG 2FP 2.12766
25 5C5H 4YB 2.12766
26 4WOE ADP 2.12766
27 3ELW SAM 2.12766
28 3ELW GP3 2.12766
29 5N5S NAP 2.12766
30 1S4M LUM 2.12766
31 4IXH IMP 2.12766
32 3PPM JG1 2.12766
33 1JGT CMA 2.12766
34 1JGT APC 2.12766
35 3GFB NAD 2.12766
36 3KRB NAP 2.12766
37 4FK7 P34 2.18341
38 5NDF LU2 2.27671
39 5NDF UDP 2.27671
40 5MRH Q9Z 2.48227
41 4LH7 NMN 2.48227
42 5FUB SAH 2.48227
43 1HDG NAD 2.48227
44 5VN0 FAD 2.48227
45 1Y8Q ATP 2.48227
46 4L9Z COA 2.48227
47 1VMK GUN 2.52708
48 3EVF SAH 2.52708
49 5LX6 78P 2.6178
50 1OJZ NAD 2.83019
51 5W75 SUC 2.83688
52 2GMH FAD 2.83688
53 1KYZ SAH 2.83688
54 4H03 NAD 2.83688
55 6GAS FAD 2.83688
56 1CT9 AMP 2.83688
57 4ZUL UN1 2.83688
58 2DFV NAD 2.83688
59 1KYZ FER 2.83688
60 6B92 SAH 2.83688
61 3EYA TDP 2.83688
62 1J0D 5PA 2.83688
63 1GZF NIR 2.8436
64 1GZF ADP 2.8436
65 1GZF NAD 2.8436
66 4R38 RBF 2.85714
67 3JSX CC2 2.9304
68 3JSX FAD 2.9304
69 1QL9 ZEN 3.13901
70 6GFK SAH 3.18725
71 5U3F 7TS 3.19149
72 3DAA PDD 3.19149
73 4GV4 MEJ 3.19149
74 4PAB THG 3.19149
75 4X9X OLA 3.19149
76 4A22 TD4 3.19149
77 2FJK 13P 3.19149
78 5BVE 4VG 3.19149
79 2XIQ MLC 3.19149
80 1T90 NAD 3.19149
81 1GZ6 NAI 3.19149
82 4KIB SAH 3.19149
83 1U72 MTX 3.22581
84 1U72 NDP 3.22581
85 2IXB NAD 3.37838
86 2A5F NAD 3.42857
87 3CBG SAH 3.44828
88 6ACS CIT 3.48837
89 1OG1 TAD 3.53982
90 5UKL SIX 3.5461
91 4B2Z P5S 3.5461
92 6MPT C30 3.5461
93 1DMR PGD 3.5461
94 3KJD 78P 3.5461
95 3CKJ CIT 3.5461
96 1O9J NAD 3.5461
97 3GCZ SAM 3.5461
98 3GAY P6T 3.5461
99 1VJY 460 3.5461
100 4M73 M72 3.5461
101 4M73 SAH 3.5461
102 6CBO DOW 3.5461
103 4R84 CSF 3.5461
104 2WZG UPG 3.5461
105 3JZ4 NAP 3.5461
106 5UCD NAP 3.5461
107 4YBN FAD 3.57143
108 3HVJ 705 3.61991
109 1WXI AMP 3.63636
110 1AOE GW3 3.64583
111 1AOE NDP 3.64583
112 1EFY BZC 3.71429
113 3VRY B43 3.90071
114 2PA4 UPG 3.90071
115 6CBN OZY 3.90071
116 1PL6 572 3.90071
117 4Z0G 5GP 3.90071
118 1PL6 NAD 3.90071
119 3DLG GWE 3.90071
120 5YSI NCA 3.94737
121 4WUJ FMN 4.08163
122 4LAE 1VM 4.19162
123 4LAE NAP 4.19162
124 1NV8 SAM 4.22535
125 1NV8 MEQ 4.22535
126 1EU1 MGD 4.25532
127 2C6Q IMP 4.25532
128 2BLE 5GP 4.25532
129 2B5W NAP 4.25532
130 5ZW3 SAH 4.44444
131 5VJE GOS 4.46927
132 1G2O IMH 4.47761
133 5A89 FMN 4.48718
134 4YC0 5OF 4.60251
135 4UUG PXG 4.60993
136 2C5S AMP 4.60993
137 1LVW TYD 4.60993
138 2WN6 NDP 4.60993
139 3EFV NAD 4.60993
140 1ZBQ NAD 4.60993
141 5WP5 SAH 4.60993
142 5WYF ILP 4.60993
143 1XK9 P34 4.65116
144 1JG3 ADN 4.68085
145 4PTZ FMN 4.71204
146 1S7G NAD 4.74308
147 4X6F 3XU 4.7619
148 3B82 NAD 4.83092
149 3KYG 5GP 5GP 4.84582
150 4R81 FMN 4.85437
151 5XDT ZI7 4.87013
152 3DUW SAH 4.93274
153 2XHK AKG 4.95496
154 5F7J ADE 4.96454
155 2XXP DSL 4.96454
156 5X8G S0N 4.96454
157 3LVW GSH 4.96454
158 1O5R FR9 4.96454
159 1U2Z SAH 4.96454
160 1F76 FMN 4.96454
161 4QAR ADE 4.97512
162 5F7N NAG GAL FUC FUC A2G 5
163 5JZI LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL 5
164 5F7Y GLC GAL NAG GAL FUC A2G 5
165 2F59 INI 5.09554
166 5K3W PLP 5.11182
167 3ESS 18N 5.21739
168 3LF0 ATP 5.26316
169 5N5D SAM 5.30973
170 4GLJ RHB 5.31915
171 1H0H 2MD 5.31915
172 3VZ3 SSN 5.31915
173 3VZ3 NAP 5.31915
174 5UAV NDP 5.31915
175 5UAV TFB 5.31915
176 1H0H MGD 5.31915
177 3RHJ NAP 5.31915
178 4RT1 C2E 5.35714
179 2HNK SAH 5.43933
180 5ZJ5 NAI 5.55556
181 4XSH NAI 5.58659
182 3O8M BGC 5.67376
183 3O8M GLC 5.67376
184 4BLW AMP 5.67376
185 4BLW SAH 5.67376
186 2VAP GDP 5.67376
187 1ELI PYC 5.67376
188 5E72 SAM 5.67376
189 4BUY F37 5.83333
190 5ULP KB1 5.97015
191 4POO SAM 6
192 4NBU NAI 6
193 4PJT 2YQ 6.02837
194 4IVG ANP 6.02837
195 1CER NAD 6.02837
196 4PLT NAI 6.02837
197 2X24 X24 6.02837
198 4IPE ANP 6.02837
199 2NV4 SAM 6.12245
200 1I52 CTP 6.35593
201 4I8P NAD 6.38298
202 2Z7R STU 6.38298
203 2EG5 SAH 6.38298
204 3VSE SAH 6.38298
205 1OFU GDP 6.38298
206 5EWK P34 6.5
207 3KPB SAM 6.55738
208 1GAD NAD 6.73759
209 4FXQ G9L 6.73759
210 2XKO AKG 6.74157
211 2DTX BMA 6.81818
212 5VNF VAL THR SER VAL VAL 7.00637
213 3E2M E2M 7.02703
214 3LGS ADE 7.11611
215 3LGS SAH 7.11611
216 1TLG GAL 7.2
217 4CS4 AXZ 7.29927
218 4CS4 ANP 7.29927
219 4MSG 2C6 7.37327
220 1G8K MGD 7.44681
221 5I7A 68Q 7.44681
222 2X06 NAD 7.44681
223 1VM6 NAD 7.45614
224 1MDC PLM 7.57576
225 6ECT SAM 7.80142
226 2OYS FMN 7.85124
227 1MFI FHC 7.89474
228 4Z9D NAD 8
229 2E7Z MGD 8.15603
230 3NRR D16 8.15603
231 3DMH SAM 8.39895
232 3DMH GMP 8.39895
233 4H2D FMN 8.48485
234 2IVD ACJ 8.51064
235 3VC1 SAH 8.51064
236 5UNJ RJW 8.57143
237 5UC4 83S 8.63636
238 6E48 4OA 8.84956
239 3SUD SUE 8.86699
240 2ZMF CMP 8.99471
241 2Z9C FMN 9
242 3OLL EST 9.16667
243 3N9R TD3 9.44625
244 3C56 PH4 9.44625
245 4R3U 3KK 9.49367
246 4R3U 3HC 9.49367
247 2ART LPA AMP 9.54198
248 4N82 FMN 9.55056
249 1R27 MGD 9.57447
250 3BXF 13P 9.80392
251 3BXF FBP 9.80392
252 1GR0 NAD 9.92908
253 4YMH SAH 10
254 5CLO NS8 10.1695
255 5NWD 9C8 10.2041
256 3WB0 FEG 10.241
257 2IU8 PLM 10.2837
258 1KY8 NAP 10.2837
259 3OQJ 3CX 10.5058
260 4I3V NAD 10.6383
261 1K27 MTM 10.9929
262 2C29 NAP 11.3475
263 4JWH SAH 11.5016
264 2A8Y MTA 12.2222
265 4YMZ 13P 12.3506
266 4WKB TDI 12.7049
267 1PZG A3D 12.766
268 4YCA NDP 12.9252
269 3MB5 SAM 12.9412
270 2A9K NAD 13.369
271 3BL6 FMC 13.913
272 5KVA SAM 14.0288
273 5I60 67W 14.1844
274 1WOR RED 14.1844
275 6C5F 7L9 14.5299
276 3B4Y F42 14.8936
277 4WKC BIG 15.102
278 2IV2 MGD 16.6667
279 3DJF BC3 18.0851
280 5DYO FLU 18.3486
281 1ZMT RNO 18.5039
282 3A5Z KAA 18.8482
283 2P4S DIH 19.8582
284 2A0W DIH 20.2128
285 5ETJ IM5 20.2128
286 1B8O IMH 20.922
287 1C3X 8IG 21.4286
288 5IFK HPA 21.9858
289 3BJE URA 22.3404
290 5WS9 AMP 24.1135
291 3KVY URA 24.8227
292 3KVY R2B 24.8227
293 4BMX ADE 29.0837
294 4FFS BIG 30.9623
295 2FTB OLA 31.2
296 5TBS ADE 31.5603
297 1ZOS MTM 31.7391
298 6AYR BIG 35.2941
299 6F4W FMC 40.3433
300 4DA6 GA2 41.1067
301 1NW4 IMH 41.3043
302 1VHW ADN 41.502
303 3U40 ADN 41.7355
304 1A69 FMB 43.2773
305 2AC7 ADN 45.1064
306 1JE1 GMP 45.7627
Pocket No.: 2; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 70
This union binding pocket(no: 2) in the query (biounit: 3qpb.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2EB5 OXL 1.49813
2 3BP1 GUN 1.77305
3 5DK4 ATP 2.12766
4 5DK4 5BX 2.12766
5 3ITJ FAD 2.12766
6 4BWL MN9 2.12766
7 5K9B FMN 2.22222
8 4IF4 BEF 2.40385
9 2D1S SLU 2.48227
10 2FAH GDP 2.48227
11 2VAR ANP 2.48227
12 4D57 ARG AMP 2.83688
13 3EYA TDP 2.83688
14 2CJF RP4 3.18471
15 2DHC DCE 3.19149
16 5X68 FAD 3.19149
17 1T3D CYS 3.19149
18 4PVV HO4 3.19149
19 4JWJ SAH 3.19149
20 4M0R 644 3.5461
21 1TLL FMN 3.90071
22 1O7Q UDP 3.90071
23 1O7Q GAL NAG 3.90071
24 5BSR AMP 3.90071
25 1S16 ANP 3.90071
26 4RF7 ARG 3.90071
27 5O4J SAH 4.0146
28 5O4J 9KH 4.0146
29 5O4J PJL 4.0146
30 3GD4 NAD 4.25532
31 3GD4 FAD 4.25532
32 1X87 NAD 4.60993
33 3G5S FAD 4.60993
34 5X8G S0N 4.96454
35 5WXU FLC 5.31915
36 1Q1R FAD 5.31915
37 6MVU K4V 6.02837
38 3VPH NAD 6.38298
39 3VPH OXM 6.38298
40 1NVM NAD 6.38298
41 6HT0 GQ8 6.45161
42 5IDM ANP 6.70391
43 5KVS 6XR 7.0922
44 5KVS NAP 7.0922
45 3LGS ADE 7.11611
46 3LGS SAH 7.11611
47 2IVD FAD 8.51064
48 2CXS F6P 11.3475
49 1AG9 FMN 12
50 2WC1 FMN 12.6374
51 4WKB TDI 12.7049
52 3A70 NPO 13.4752
53 3BL6 FMC 13.913
54 5I60 67W 14.1844
55 4WKC BIG 15.102
56 5MQ6 NDP 16.6667
57 3BJE R1P 22.3404
58 3KVY R2B 24.8227
59 4BMX ADE 29.0837
60 4FFS BIG 30.9623
61 1ZOS MTM 31.7391
62 6AYR BIG 35.2941
63 6F4W FMC 40.3433
64 4DA6 GA2 41.1067
65 1NW4 IMH 41.3043
66 1VHW ADN 41.502
67 3U40 ADN 41.7355
68 1A69 FMB 43.2773
69 2AC7 ADN 45.1064
70 1JE1 GMP 45.7627
Pocket No.: 3; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 59
This union binding pocket(no: 3) in the query (biounit: 3qpb.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 6ALW BNV 1.38889
2 3LA3 2FT 1.64609
3 5ICK FEZ 1.74672
4 1QZR ANP 2.12766
5 4C01 QY9 2.12766
6 2WKV COA 2.12766
7 1XNG ATP 2.23881
8 3PP0 03Q 2.48227
9 2BJK NAD 2.48227
10 1AJQ SPA 2.83688
11 1D01 ACE MET LEU SER VAL GLU GLU GLU GLY 2.97619
12 5B0W 22B 3.19149
13 3NKS ACJ 3.19149
14 4HIA FMN 3.40909
15 1KZN CBN 3.41463
16 1Q19 APC 3.57853
17 2RDQ AKG 3.90071
18 3UDZ ADP 3.90071
19 5DDW 5B6 3.90071
20 4JEJ 1GP 4.09836
21 3CQD ATP 4.20712
22 5TUF FAD 4.25532
23 5X5U NAD 4.25532
24 5H2U 1N1 4.49438
25 4QAC KK3 4.60829
26 6GEH FAD 4.6875
27 3RMK BML 4.96454
28 2ADA HPR 4.96454
29 2VGK REZ 4.96454
30 2IVF MGD 5.14019
31 3IVV ASP GLU VAL THR SER THR THR SER SER SER 5.51724
32 4OZJ ADP 5.59441
33 5LHT TIH 5.67376
34 1FEC FAD 5.67376
35 4W6Z 8ID 5.67376
36 5ANU 58T 5.6962
37 4PLT OXM 6.02837
38 4J5R A1R 6.16438
39 1Q0S SAH 6.17761
40 5IDM ANP 6.70391
41 2WBP SIN 6.73759
42 2WBP ZZU 6.73759
43 5W4W 9WG 7.0922
44 4H8N NDP 7.0922
45 1J2J GTP 7.22892
46 4WHZ 3NL 7.44681
47 2WOX NDP 7.44681
48 3QXV MTX 7.93651
49 2H04 4UN 8.15603
50 1YUC EPH 8.23529
51 2DSA HPX 8.37438
52 2DSA GSH 8.37438
53 3GDH SAH 8.71369
54 3Q9O NAD 8.86525
55 4PZ2 NAD 9.57447
56 5L13 6ZE 9.92908
57 4MIX UD1 9.92908
58 2G5C NAD 13.5231
59 4II2 ATP 14.8936
Pocket No.: 4; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 49
This union binding pocket(no: 4) in the query (biounit: 3qpb.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1RJW ETF 1.77305
2 5TWJ SAM 1.85185
3 3D91 REM 2.12766
4 4ZH7 FUC GAL NAG GAL FUC 2.12766
5 1WDK ACO 2.12766
6 3S5W FAD 2.12766
7 5Z2F NAP 2.26415
8 3WYJ H78 2.37154
9 4J3L AJ5 2.38095
10 2XVD AS6 2.48227
11 3C1X CKK 2.48227
12 1T5B FMN 2.48756
13 3PNQ 2HA 2.83688
14 5HCY 60D 2.83688
15 5LYH 7B8 3.10881
16 4D9C PMP 3.19149
17 1D4O NAP 3.26087
18 4ONA UW1 3.5461
19 3HXU A5A 3.5461
20 6BQ6 TER 3.90071
21 1G55 SAH 3.90071
22 4XZ3 COA 3.91304
23 6BJO DUY 4
24 2C6Q NDP 4.25532
25 5W8Q BU4 4.25532
26 1GTE IUR 4.60993
27 1GTE FMN 4.60993
28 2BJ4 OHT 4.7619
29 6AMI TRP 4.96454
30 5UC1 486 5.40541
31 2A92 NAI 5.67376
32 5UR0 NAD 5.67376
33 6GAQ FMN 5.84416
34 1WG8 SAM 6.02837
35 2WUF KEM 6.02837
36 5AHM IMP 6.25
37 3OA2 NAD 6.38298
38 5XGX DAS DLY 6.73759
39 4XUC 43G 7.33945
40 4XUC SAM 7.33945
41 1QD0 RR6 8.59375
42 4QTU SAM 8.88889
43 2Z9C DTC 9
44 1PN4 HDC 10.7143
45 6EK3 OUL 13.5747
46 1MLD CIT 14.1844
47 4BMO FMN 14.2857
48 2GCE SFC 15.9574
49 2GCE RFC 15.9574
Pocket No.: 5; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 12
This union binding pocket(no: 5) in the query (biounit: 3qpb.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6F7L FAD 1.77305
2 5TUK FAD 2.12766
3 1YQS BSA 2.12766
4 3MJY IJZ 2.48227
5 3MJY FMN 2.48227
6 1J0D 5PA 2.83688
7 2RGJ FAD 3.48259
8 4BHL ARG 3.65169
9 4CQE CQE 3.95683
10 2RAB FAD 5.67376
11 4I9B NAD 6.73759
12 3RF4 FUN 7.75862
Pocket No.: 6; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 20
This union binding pocket(no: 6) in the query (biounit: 3qpb.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1BVY FMN 2.12766
2 3A06 NDP 2.48227
3 2BJK NAD 2.48227
4 5U3F 7TS 3.19149
5 2HQM FAD 3.5461
6 1VFS DCS 3.5461
7 2W5P CL8 4.02685
8 4BV6 FAD 4.25532
9 3N39 FMN 4.25532
10 5X30 HCS 4.60993
11 4QAR ADE 4.97512
12 1U3G THF 5.29101
13 1FEC FAD 5.67376
14 4XW2 SIM 8.08081
15 4Y4V DAL 8.15603
16 2RL1 UD1 8.51064
17 4PZ2 NAD 9.57447
18 2R4J 13P 9.92908
19 2R4J FAD 9.92908
20 3Q9T FAY 10.2837
Pocket No.: 7; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 6
This union binding pocket(no: 7) in the query (biounit: 3qpb.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 6HOY TSN 3.19149
2 3IWJ NAD 3.19149
3 1UWK URO 7.44681
4 1UWK NAD 7.44681
5 5ECP MET 13.0045
6 5XFV FMN 16.3121
Pocket No.: 8; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 8
This union binding pocket(no: 8) in the query (biounit: 3qpb.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5IUW IAC 4.25532
2 5IUW NAD 4.25532
3 1PVN MZP 4.78723
4 1RC0 KT5 5.26316
5 16PK BIS 5.67376
6 3UZO GLU 6.38298
7 4ZNO SUC 6.73759
8 2IU8 PLM 10.2837
Pocket No.: 9; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 24
This union binding pocket(no: 9) in the query (biounit: 3qpb.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 3EVF GTA 2.52708
2 5JFL NAD 2.67176
3 4BTV RB3 3.19149
4 4BG4 ADP 3.65169
5 4LWP SAH 3.90071
6 2J8Z NAP 3.90071
7 4Z87 5GP 3.90071
8 1EP2 FMN 4.60993
9 1EP2 ORO 4.60993
10 2NSJ C2R 4.73373
11 6CUZ FEV 4.96454
12 4AF0 IMP 4.96454
13 2BYS LOB 5.28634
14 1T9D PYD 6.20384
15 1T9D FAD 6.20384
16 1T9D 1MM 6.20384
17 1T9D P25 6.20384
18 3O9L LPN 6.25
19 2VYN NAD 6.73759
20 3THR C2F 6.82594
21 3EQO LGC 8.15603
22 3L4S NAD 9.57447
23 3L4S 3PG 9.57447
24 3C3N FMN 13.1206
Pocket No.: 10; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 5
This union binding pocket(no: 10) in the query (biounit: 3qpb.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1JXN MFU 3.71901
2 5VW2 NAP 4.60993
3 5VW2 FDA 4.60993
4 4W6Z 8ID 5.67376
5 5L13 6ZE 9.92908
Pocket No.: 11; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 68
This union binding pocket(no: 11) in the query (biounit: 3qpb.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 1Q2C COA None
2 2PT9 2MH 1.77305
3 5MJI 7O6 1.94553
4 5Y8L NAD 2.0339
5 5BVA FAD 2.12766
6 3B6R ADP 2.12766
7 1YOA FAD 2.51572
8 5CUQ NSC 2.62172
9 1NFS DED 2.73224
10 4OKZ 3E9 2.83688
11 5M67 3D1 2.83688
12 5M67 NAD 2.83688
13 5T8U LPA 2.83688
14 5LRT ADP 2.83688
15 2ZKJ ADP 2.83688
16 5YU3 PRO 3.19149
17 5YU3 NAD 3.19149
18 1K97 CIR 3.19149
19 1K97 ASP 3.19149
20 4PXL NAD 3.19149
21 3KB6 NAD 3.19149
22 3O3R NAP 3.19149
23 3ZIU LSS 3.19149
24 4YAG NAI 3.46021
25 5LD5 NAD 3.5461
26 3FIU AMP 3.61446
27 2XNJ NAP 3.7594
28 4PVD NDP 3.90071
29 5OUH L0B 3.90244
30 4BGB ADP 4
31 2FZW NAD 4.25532
32 5IUW NAD 4.25532
33 5IUW IAC 4.25532
34 6EOZ 58K 4.60993
35 6EOZ AKG 4.60993
36 3LPP KTL 4.60993
37 2J9C ATP 5.04202
38 3W8X FTK 5.67376
39 3W8X FAD 5.67376
40 1ZEM NAD 5.72519
41 3P7N FMN 5.81395
42 4JBL MET 6.02837
43 5VM6 9EG 6.56934
44 2ZJ1 ARJ 6.73759
45 2ZJ1 NAD 6.73759
46 5JE8 NAD 6.73759
47 4KBA 1QM 7.0922
48 3G6K POP 7.0922
49 3G6K FAD 7.0922
50 2E5A LAQ 7.44681
51 2HSA FMN 7.44681
52 5DKK FMN 7.58621
53 3C6K MTA 7.80142
54 3C6K SPD 7.80142
55 1U1I NAD 7.80142
56 2VHW NAI 8.15603
57 1D1T NAD 8.15603
58 1EJ0 SAM 8.33333
59 3A2Q ACA ACA 8.51064
60 1HSK FAD 8.51064
61 3O03 NAP 9.21986
62 3NJ4 NAD 10.6383
63 1MUU NAD 11.3475
64 4WCX ALA 11.3475
65 3L5R 47X 13.9344
66 1N07 FMN 15.3374
67 2IV2 2MD 16.6667
68 1RLJ FMN 20.1439
Pocket No.: 12; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 13
This union binding pocket(no: 12) in the query (biounit: 3qpb.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1M15 ADP 2.12766
2 1M15 ARG 2.12766
3 4PIO SAH 2.48227
4 4B0T ADP 2.83688
5 3G2O SAM 2.83688
6 4FAJ LEU VAL THR LEU VAL PHE VAL 3.5461
7 1M2O GNP 3.68421
8 1GVF PGH 4.96454
9 3WG6 NDP 6.38298
10 3G89 SAM 6.4257
11 6C5B SAH 7.44681
12 4YQE PLQ 8.15603
13 4YQE FMN 8.15603
Pocket No.: 13; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 61
This union binding pocket(no: 13) in the query (biounit: 3qpb.bio3) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4MIB 28M 2.12766
2 4L50 D8X 2.25564
3 1NMK SFM 2.42424
4 2EFJ SAH 2.48227
5 5J75 6GQ 2.65152
6 2PWY SAH 2.71318
7 2V3V MGD 2.83688
8 5JJR SAH 2.83688
9 4CQM NAP 2.86885
10 2QRK AMP 3.19149
11 2P41 SAH 3.19149
12 6FDF SAH 3.19149
13 1TRD PGH 3.2
14 5TA6 79D 3.35196
15 2IXB A2G 3.37838
16 5ALC TIQ 3.4188
17 1WVC CTP 3.4749
18 5YAP NAI 3.5461
19 3TAO PGH 3.74532
20 5MGZ SAH 3.81356
21 2YAK OSV 3.90071
22 2RIO ADP 3.90071
23 4AGS GSH 3.90071
24 3PE2 E1B 4.25532
25 3R75 BEZ 4.25532
26 6H5E ANP 4.25532
27 5VW2 NAP 4.60993
28 5VW2 FDA 4.60993
29 4KRI SAH 4.60993
30 2FK8 SAM 4.60993
31 5X2Z 3LM 4.60993
32 2JHP SAH 4.60993
33 4C12 UML 4.60993
34 5XDT GDP 4.87013
35 6CGD AKN 4.96454
36 6CGD GNP 4.96454
37 3X0Y FMN 4.96454
38 3L9R L9Q 5.10204
39 1R4A GNP 5.45455
40 3B2Q ATP 5.54371
41 1SW0 PGA 5.64516
42 1U6R ADP 5.67376
43 5WKC FAD 6.20384
44 3KJS DQ1 6.38298
45 6H3O FAD 6.38298
46 1VA6 P2S 6.73759
47 1VA6 ADP 6.73759
48 1KOL NAD 7.03518
49 3LKZ SFG 7.0922
50 5YRV 5AD 7.29927
51 5XNC MTA 7.81671
52 3RG9 NDP 7.91667
53 3RG9 WRA 7.91667
54 1USF FMN 8.42697
55 1USF NAP 8.42697
56 2VPY MGD 10.2564
57 2OQ2 A3P 12.2605
58 5L9N ATP 14.2857
59 1V3S ATP 14.6552
60 1RL4 BRR 15.4255
61 2BZG SAH 15.5172
Pocket No.: 14; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 33
This union binding pocket(no: 14) in the query (biounit: 3qpb.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5KF6 NAD 2.12766
2 1QMG APX 2.48227
3 4CQM NAP 2.86885
4 1T90 NAD 3.19149
5 4PXL NAD 3.19149
6 5L2M 6ZY 3.5461
7 1O9J NAD 3.5461
8 3A2Y TS5 3.5533
9 1Q19 APC 3.57853
10 4A0M NAD 3.90071
11 1QPB PYM 3.90071
12 3VCY UD1 3.90071
13 4OXI GAP 3.90071
14 2IO8 ADP 3.90071
15 5D4V SAH 5.22388
16 1OBV FMN 5.31915
17 4WOP CTP 5.33333
18 3R77 QLI 5.74163
19 4XOI GTP 6.02837
20 2NV4 SAM 6.12245
21 4I8P NAD 6.38298
22 3X0V FAD 6.73759
23 5FNU L6I 8.15603
24 1MI3 NAD 8.15603
25 3NRZ FAD 8.15603
26 3Q87 SAM 8.23529
27 1JNR FAD 8.66667
28 4R57 ACO 9.09091
29 4I3V NAD 10.6383
30 5JNW 6LJ 10.6918
31 1UM0 FMN 11.3475
32 3C3N FMN 13.1206
33 5WS9 AMP 24.1135
Pocket No.: 15; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 15) in the query (biounit: 3qpb.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 16; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 20
This union binding pocket(no: 16) in the query (biounit: 3qpb.bio3) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1MLY ACZ PLP 2.12766
2 5XET ME8 2.83554
3 5DQ8 FLF 2.91667
4 2RHO GSP 3.07692
5 1S17 GNR 3.88889
6 1NHZ 486 3.92857
7 4PQG NAG 4.60993
8 5X30 4LM 4.60993
9 2GJN NIS 4.96454
10 2GJN FMN 4.96454
11 4Y7U 2KH 5.62771
12 1HV9 UD1 5.67376
13 1B7H LYS NLE LYS 5.67376
14 4KXQ APR 6.40569
15 1L3I SAH 6.77083
16 1W5F G2P 7.08215
17 1QRD FAD 7.32601
18 1HXD BTN 9.57447
19 5DJU FMN 13.1034
20 2EW5 Y12 13.8122
Pocket No.: 17; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 22
This union binding pocket(no: 17) in the query (biounit: 3qpb.bio3) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 2Z6D FMN None
2 1LBT T80 1.77305
3 5DWQ SFG 1.77305
4 5DX1 SFG 1.77305
5 6APL C5P 2.12766
6 5VN0 NAI 2.48227
7 4IWN GEK 2.62009
8 4KM2 TOP 2.7933
9 5MDH NAD 2.83688
10 4UWJ 7L5 3.5461
11 4UWJ MYA 3.5461
12 1UXG NAD 3.90071
13 1UXG FUM 3.90071
14 5Y0T TAT 3.90071
15 5M3Z PY6 6.73759
16 5M3Z NLE 6.73759
17 4LOO SB4 7.0922
18 2UZH CDP 7.27273
19 4FZV SAM 9.20502
20 4IDN GNP 11.1597
21 4OM8 NAD 11.3475
22 2VUT NAD 16.2791
Pocket No.: 18; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 4
This union binding pocket(no: 18) in the query (biounit: 3qpb.bio3) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5TUF TDC 4.25532
2 4ZGS NAD 7.0922
3 3L9W FMN 9.92908
4 1JQ9 PHE LEU SER TYR LYS 12.3967
Pocket No.: 19; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 4
This union binding pocket(no: 19) in the query (biounit: 3qpb.bio3) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5DX8 SFG 1.77305
2 2Z6C FMN 6.20155
3 4PLG NAI 8.51064
4 4PLG OXM 8.51064
Pocket No.: 20; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 20
This union binding pocket(no: 20) in the query (biounit: 3qpb.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1JQY A32 None
2 3A7R LAQ 1.41844
3 4YWV SSN 2.12766
4 4RUS NDG 2.52101
5 4RUS NAG 2.52101
6 1GPE FAD 3.19149
7 3CV2 COA 3.19149
8 2IMP NAI 3.5461
9 3JZ4 NAP 3.5461
10 5J60 FAD 3.5461
11 1I8T FAD 3.90071
12 5FPE 3TR 4.60993
13 3VZ3 NAP 5.31915
14 4RKK GLC GLC GLC GLC GLC GLC 5.31915
15 2VDF OCT 5.5336
16 2B6N ALA PRO THR 6.83453
17 5N2I NAP 7.32759
18 2RG0 CBI 8.15603
19 5T2Z 017 13.1313
20 4G6I RS3 13.8095
Pocket No.: 21; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 3
This union binding pocket(no: 21) in the query (biounit: 3qpb.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2G50 ALA 1.77305
2 1QPB TPP 3.90071
3 2WPB ZZI 6.73759
Pocket No.: 22; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 15
This union binding pocket(no: 22) in the query (biounit: 3qpb.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1Y52 BTN None
2 3S5W NAP 2.12766
3 4UP3 FAD 2.48227
4 1DL5 SAH 3.19149
5 1CZR FMN 3.5503
6 2OKL BB2 3.78378
7 4XU6 TDA 3.80952
8 5Y77 FAD 3.90071
9 5UWP GNP 4.96454
10 4HAT GNP 4.96454
11 3WYF GTP 5.93607
12 1WA5 GTP 8.15603
13 5U19 827 10.6383
14 5U19 SAH 10.6383
15 4JWH SAH 11.5016
Pocket No.: 23; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 2
This union binding pocket(no: 23) in the query (biounit: 3qpb.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 3AB1 FAD 4.60993
2 1H6H PIB 19.5804
Pocket No.: 24; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 3
This union binding pocket(no: 24) in the query (biounit: 3qpb.bio3) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 5KF6 NAD 2.12766
2 5B25 4QJ 4.60993
3 3ZLR X0B 7.59494
Pocket No.: 25; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 3
This union binding pocket(no: 25) in the query (biounit: 3qpb.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 4GAA BES 4.96454
2 1KQF MGD 7.0922
3 2DT5 NAD 7.58294
Pocket No.: 26; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 7
This union binding pocket(no: 26) in the query (biounit: 3qpb.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1QZR CDX 2.12766
2 1ZXM ANP 2.48227
3 5M60 BGC 2.48227
4 4HVA 4HV 3.77358
5 3D04 SAK 4.40252
6 4ZSI 4R1 5.26316
7 3NK7 SAM 7.58123
Pocket No.: 27; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 1
This union binding pocket(no: 27) in the query (biounit: 3qpb.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5C5H 4YB 2.12766
Pocket No.: 28; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 1
This union binding pocket(no: 28) in the query (biounit: 3qpb.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 4CNK FAD 3.19149
Pocket No.: 29; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 29) in the query (biounit: 3qpb.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 30; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 6
This union binding pocket(no: 30) in the query (biounit: 3qpb.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 3KEE 30B 1.05263
2 2NYA MGD 1.77305
3 3ZOK NAD 1.85185
4 4Y24 TD2 3.24675
5 6AM8 TRP 4.96454
6 2F6U CIT 6.41026
Pocket No.: 31; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 1
This union binding pocket(no: 31) in the query (biounit: 3qpb.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1CLU DBG 3.01205
Pocket No.: 32; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 5
This union binding pocket(no: 32) in the query (biounit: 3qpb.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 2YOO K2B 2.12766
2 4WZH FMN 3.19149
3 3IWJ NAD 3.19149
4 5LJB RTL 6.66667
5 5D48 L96 9.86842
Pocket No.: 33; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: 1
This union binding pocket(no: 33) in the query (biounit: 3qpb.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1SZD APR 9.92908
Pocket No.: 34; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 34) in the query (biounit: 3qpb.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 35; Query (leader) PDB : 3QPB; Ligand: R1P; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 35) in the query (biounit: 3qpb.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 36; Query (leader) PDB : 3QPB; Ligand: URA; Similar sites found with APoc: 1
This union binding pocket(no: 36) in the query (biounit: 3qpb.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 2RHQ GAX 11.7021
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