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Receptor
PDB id Resolution Class Description Source Keywords
3QKT 1.9 Å EC: 3.6.-.- RAD50 ABC-ATPASE WITH ADJACENT COILED-COIL REGION IN COMPLEX PNP PYROCOCCUS FURIOSUS RECA-LIKE FOLD COILED-COILS ATPASE ATP BINDING DNA BINDIMRE11 REPLICATION
Ref.: ABC ATPASE SIGNATURE HELICES IN RAD50 LINK NUCLEOTI TO MRE11 INTERFACE FOR DNA REPAIR. NAT.STRUCT.MOL.BIOL. V. 18 423 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:901;
B:901;
C:901;
D:901;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:902;
B:902;
C:902;
D:902;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3QKT 1.9 Å EC: 3.6.-.- RAD50 ABC-ATPASE WITH ADJACENT COILED-COIL REGION IN COMPLEX PNP PYROCOCCUS FURIOSUS RECA-LIKE FOLD COILED-COILS ATPASE ATP BINDING DNA BINDIMRE11 REPLICATION
Ref.: ABC ATPASE SIGNATURE HELICES IN RAD50 LINK NUCLEOTI TO MRE11 INTERFACE FOR DNA REPAIR. NAT.STRUCT.MOL.BIOL. V. 18 423 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4NCJ - ADP BEF n/a n/a
2 3QKT - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 4NCJ - ADP BEF n/a n/a
2 3QKT - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4NCJ - ADP BEF n/a n/a
2 3QKT - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3QKT; Ligand: ANP; Similar sites found with APoc: 673
This union binding pocket(no: 1) in the query (biounit: 3qkt.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 2ZX2 RAM None
2 5W75 SUC 1.17994
3 5W75 GDP 1.17994
4 4RZ3 ADP 1.35593
5 5URY PAM 1.36986
6 1VHT BA3 1.37615
7 4ZNL BEF ADP 1.45985
8 2FAH GDP 1.47493
9 1E2K TMC 1.51057
10 4V03 ADP 1.55642
11 1BH2 GSP 1.5873
12 4TVD BGC 1.76991
13 4PPF FLC 1.76991
14 5HCN GCP 1.91571
15 1EQ2 ADQ 1.93548
16 2IL4 COA 1.94175
17 3R7F CP 1.97368
18 2OZE AGS 2.01342
19 1XMV ADP 2.0649
20 3TBK ANP 2.0649
21 4XFR CIT 2.0649
22 4XG0 CIT 2.0649
23 3BOS CDP 2.06612
24 6HKE LMR 2.20126
25 6HKE MLT 2.20126
26 2DVZ GLU 2.2293
27 5TSH ANP 2.35988
28 5TSH ADP 2.35988
29 5M04 GDP 2.35988
30 5I0H ADP BEF 2.35988
31 4R43 GDP 2.35988
32 6AU6 GDP 2.35988
33 1IHU AF3 2.35988
34 1IHU ADP 2.35988
35 2PZ8 APC 2.46479
36 1TAD GDP 2.46914
37 1TAD ALF 2.46914
38 4BAS GNP 2.51256
39 2F5X ASP 2.5641
40 4IEE AGS 2.65487
41 5H7K GDP 2.65487
42 5H7J GCP 2.65487
43 4ZKD GDP 2.65487
44 4Y4V DAL 2.65487
45 2C9O ADP 2.65487
46 4M3P HCS 2.65487
47 3Q9L ATP 2.69231
48 2WKQ GTP 2.71084
49 6ACS CIT 2.71318
50 1NST A3P 2.76923
51 3B8I OXL 2.78746
52 3VPD BUA 2.84698
53 3FWY ADP 2.86624
54 4WEI GLC GAL 2.88809
55 1JJV ATP 2.91262
56 2G2Y MLI 2.92208
57 2X7I CIT 2.92208
58 5FTB ANP 2.94985
59 3U6B GDP 2.94985
60 1D8T GDP 2.94985
61 4G5G GDP 2.94985
62 5JBQ GDP 2.94985
63 3U6K GDP 2.94985
64 5FHD ADP ALF 2.94985
65 3DZD ADP 2.94985
66 4PC3 GDP 2.94985
67 2BVN GNP 2.94985
68 2ZPA ADP 2.94985
69 2OBM ADP 2.94985
70 4ZG4 VO4 ADP 2.94985
71 5M7P ADP 2.94985
72 2Q2Y ADP 2.94985
73 2Q2Y MKR 2.94985
74 3VMF GTP 2.94985
75 2BEK ATP 2.94985
76 1ZCB GDP 2.94985
77 3K5I AIR 2.94985
78 5GZ9 MAN 2.95082
79 3ITJ CIT 2.95858
80 2HCJ GDP 2.98507
81 1P72 ADP 2.99401
82 4UAA 3GK 3.04183
83 4UA7 3GK 3.04183
84 3P4X ADP 3.1477
85 4TL6 ANP 3.16206
86 5K5Z ANP 3.18471
87 3FIU POP 3.21285
88 3VX3 ADP 3.22581
89 3FB4 AP5 3.24074
90 5LTJ BEF 3.24484
91 5ZBR ANP 3.24484
92 5W76 GDP 3.24484
93 6B4K ANP 3.24484
94 1G7S GDP 3.24484
95 5LB3 ADP 3.24484
96 3EZ2 ADP 3.24484
97 5LTJ ADP 3.24484
98 5KSZ GCP 3.24484
99 5HR5 ADP 3.24484
100 2XAU ADP 3.24484
101 5XDR ADP 3.24484
102 3ZOK GLY 3.24484
103 1SVK ALF GDP 3.24484
104 1F5N GNP 3.24484
105 6A20 ADP 3.24484
106 5VGR GDP 3.24484
107 1G41 ADP 3.24484
108 1NY5 ADP 3.24484
109 4TTQ ATP 3.25581
110 4LC1 GDP 3.2641
111 2Y8E GNP 3.35196
112 3E70 GDP 3.35366
113 2B8W ALF 5GP 3.35366
114 1CR1 TTP 3.37838
115 1P4V GLY 3.38983
116 4QOS ADP 3.39623
117 2RGX AP5 3.39806
118 6G14 G4P 3.40136
119 5GVR LMR 3.4188
120 3I7S PYR 3.42466
121 2CDN ADP 3.48259
122 2FFQ GSP 3.50877
123 1VKJ A3P 3.50877
124 2UVO NAG 3.50877
125 1R2Q GNP 3.52941
126 2XT3 ADP 3.53982
127 2Y65 ADP 3.53982
128 2CE7 ADP 3.53982
129 4IHQ ADP 3.53982
130 1TQ4 GDP 3.53982
131 1F9V ADP 3.53982
132 4IDN GNP 3.53982
133 4FRZ ADP 3.53982
134 2ZFI ADP 3.53982
135 2C77 GNP 3.53982
136 2C78 GNP 3.53982
137 1T0S BML 3.53982
138 3MD0 GDP 3.53982
139 4KAX GTP 3.5503
140 3MJH GTP 3.57143
141 1U8Z GDP 3.57143
142 5L3W GDP 3.59477
143 1G6O ADP 3.63636
144 5L3V GDP 3.67893
145 5L3S G 3.71622
146 5L3S GNP 3.71622
147 4BFW ZVW 3.77358
148 1US5 GLU 3.82166
149 4AG5 ADP 3.83481
150 2OG2 MLI 3.83481
151 1KK1 GNP 3.83481
152 1D2E GDP 3.83481
153 1MKY GDP 3.83481
154 2IS6 ADP 3.83481
155 1DAR GDP 3.83481
156 2J5V PCA 3.83481
157 4NCN GTP 3.83481
158 4KVA GTP 3.83481
159 5TSU CYS 3.83481
160 4TMZ GSP 3.83481
161 2QEN ADP 3.83481
162 1GP2 GDP 3.83481
163 6CRK GDP 3.83481
164 5EXT ADP 3.84615
165 5H4S RAM 3.87324
166 1PUJ GNP 3.90071
167 1G8S MET 3.91304
168 1BG2 ADP 4
169 1CS4 GSP 4
170 3ZQ6 ADP ALF 4.01235
171 3DKP ADP 4.08163
172 4JLV ADP 4.08922
173 1AKY AP5 4.09091
174 2B4D COA 4.09357
175 2WIC GNP 4.11985
176 1V8K ANP 4.12979
177 3WY9 GDP 4.12979
178 3WYA GDP 4.12979
179 1WDT GTP 4.12979
180 3FKQ ATP 4.12979
181 4PFO ADP 4.12979
182 3IO3 ADP 4.12979
183 2CUN 3PG 4.12979
184 4HSE ADP 4.12979
185 5GOE GDP 4.12979
186 1FP6 ADP 4.15225
187 1YRB GDP 4.19847
188 2QZ4 ADP 4.19847
189 4X8O AP5 4.20561
190 1O3Y GTP 4.21687
191 1Y3A GDP 4.25532
192 1RE0 GDP 4.26829
193 3BD9 A3P 4.28571
194 5EP2 AZU 4.29688
195 3B9Q MLI 4.30464
196 4WZA ACP 4.34783
197 4WZA ADP 4.34783
198 3AQ4 GDP 4.34783
199 4XZ3 ACP 4.34783
200 4M6T SAM 4.37158
201 2WHX ADP 4.42478
202 5YT0 GDP 4.42478
203 5FG3 GDP 4.42478
204 4LYA ATP 4.42478
205 5MZN ADP 4.42478
206 4A4Z ANP 4.42478
207 3ZFD ANP 4.42478
208 2JLR ANP 4.42478
209 2NCD ADP 4.42478
210 3BFV ADP 4.42804
211 1RYH GNP 4.4335
212 3H4S ADP 4.44444
213 2W58 ADP 4.45545
214 1U0J ADP 4.49438
215 1ION ADP 4.52675
216 3T1O GDP 4.54545
217 5ZB0 TYD 4.54545
218 5ZB0 ADP 4.54545
219 3CYI ATP 4.54545
220 1F6B GDP 4.54545
221 2A5F GTP 4.57143
222 5J1S ATP 4.57746
223 1NRJ GTP 4.58716
224 1KSH GDP 4.60526
225 1S3G AP5 4.60829
226 3VPB GLU 4.60993
227 1SVI GDP 4.61538
228 1G3Q ADP 4.64135
229 3RK1 ATP 4.64135
230 1WF3 GNP 4.65116
231 4ONT SIA GAL BGC 4.65116
232 1I4D GDP 4.6875
233 1E96 GTP 4.6875
234 2VB6 ADP BEF 4.69799
235 1SKQ GDP 4.71976
236 1W5T ADP 4.71976
237 4H1V GNP 4.71976
238 1W5T ANP 4.71976
239 5IRN ADP 4.71976
240 4P4T GDP 4.71976
241 4PJ3 ANP 4.71976
242 3WXM GTP 4.71976
243 5AK0 8V1 4.71976
244 4MKG AP5 4.71976
245 6DEF GCP 4.71976
246 4HE2 AMP 4.73373
247 2X77 GDP 4.7619
248 5UIV ADP 4.84582
249 5IRR GSP 4.87013
250 5J1J ANP 4.91228
251 3N5C GDP 4.93827
252 4D81 ADP 4.947
253 1Z6T ADP 5.01475
254 2ZR9 DTP 5.01475
255 1DNP MHF 5.01475
256 1XP8 AGS 5.01475
257 4OUE IPT 5.01475
258 4OHY ANP 5.01475
259 5IFS ADP 5.06329
260 2ZTS ADP 5.17928
261 6H5E ANP 5.17928
262 2D2F ADP 5.2
263 4YLG GDP 5.20231
264 2A5J GDP 5.2356
265 5UQW GDP 5.29101
266 4XGU ADP 5.30973
267 5G3Y ADP 5.30973
268 1T5C ADP 5.30973
269 4RT1 C2E 5.35714
270 5G41 AP5 5.38117
271 5TB5 GDP 5.40541
272 5TAR GDP 5.40541
273 1JI0 ATP 5.41667
274 3CX8 GSP 5.41872
275 4P3Y GDP 5.49451
276 1ZIN AP5 5.52995
277 3TMK T5A 5.55556
278 1Z0F GDP 5.58659
279 3FYH ADP 5.59006
280 1XNG ATP 5.59701
281 4YJ1 ADP 5.60472
282 4LJ9 ACP 5.60472
283 3EC1 GDP 5.60472
284 6FAA ADP 5.60472
285 5N69 ADP 5.60472
286 1Q8A HCS 5.60472
287 2FH5 GTP 5.60748
288 3TKL GTP 5.61225
289 3E5H GNP 5.61798
290 1S8F GDP 5.64972
291 3REF GDP 5.6701
292 4YDS ATP 5.70175
293 3IUY AMP 5.70175
294 4D0G GTP 5.71429
295 3DEF GDP 5.72519
296 1Z0A GDP 5.74713
297 6FA4 GNP 5.78035
298 5KSP GDP 5.78947
299 5KUT GDP 5.82011
300 5BQ5 ADP BEF 5.82011
301 1Z06 GNP 5.82011
302 5WDR GNP 5.84795
303 4K81 GTP 5.84795
304 3GJ4 GDP 5.88235
305 3GJ7 GDP 5.88235
306 3GJ5 GDP 5.88235
307 3GJ3 GDP 5.88235
308 3GJ8 GDP 5.88235
309 3GJ0 GDP 5.88235
310 5FII PHE 5.88235
311 1XKV ATP 5.8997
312 3HU3 AGS 5.8997
313 5WC2 ADP 5.8997
314 2GKS ADP 5.8997
315 2CBZ ATP 5.90717
316 2BME GNP 5.91398
317 5O2T GSP 5.91716
318 3RAB GNP 5.91716
319 4JLS 3ZE 5.92105
320 3WYF GTP 5.93607
321 3M1I GTP 5.93607
322 1YZN GNP 5.94595
323 1BO4 COA 5.95238
324 2IMG MLT 5.96026
325 1M7B GTP 5.97826
326 6BVI GNP 5.98802
327 6BVL GNP 5.98802
328 6BVK GNP 5.98802
329 6D5H GNP 5.98802
330 6D5E GNP 5.98802
331 6D5J GNP 5.98802
332 6D56 GNP 5.98802
333 6D55 GNP 5.98802
334 6BVJ GNP 5.98802
335 6D59 GNP 5.98802
336 6D5G GNP 5.98802
337 6D5V GNP 5.98802
338 4NE2 ADP 5.98802
339 4NE2 SH2 5.98802
340 6D5L GNP 5.98802
341 6BVM GNP 5.98802
342 6D5M GNP 5.98802
343 5BXQ GDP 6.01852
344 3CH5 GDP 6.01852
345 1WQ1 AF3 6.0241
346 2UZI GTP 6.0241
347 1CLU DBG 6.0241
348 1WQ1 GDP 6.0241
349 3KUD GDP 6.0241
350 1NVV GNP 6.0241
351 5WLB GNP 6.0241
352 2F9L GDP 6.03015
353 4Q1A 2XZ 6.07143
354 4Q1A UDP 6.07143
355 3SFV GDP 6.07735
356 1MR3 G3D 6.07735
357 4FCW ADP 6.10932
358 1FQJ GDP 6.12245
359 1FQK GDP 6.12245
360 1SQ5 ADP 6.16883
361 5BN3 ADP 6.19469
362 4PX9 ADP 6.19469
363 4DCT GDP 6.19469
364 1LVK MNT BEF 6.19469
365 1IBR GNP 6.19469
366 1Q19 APC 6.19469
367 1W0J ADP BEF 6.25
368 1W0J ADP 6.25
369 1OIX GDP 6.28272
370 1OIV GDP 6.28272
371 3NKV GNP 6.28571
372 1IN4 ADP 6.28743
373 1M2O GNP 6.31579
374 4LHW GNP 6.32184
375 3QBT GNP 6.32184
376 3TNF GNP 6.32184
377 5U32 GDP 6.35593
378 4URS C2E 6.38298
379 1Z0K GTP 6.39535
380 2XTN GTP 6.41026
381 1ZJ6 G3D 6.41711
382 4QM7 GTP 6.43275
383 2B4B COA 6.43275
384 5W7Q GDP 6.43432
385 1G16 GDP 6.47059
386 3RWO GDP 6.48649
387 5JCP GDP ALF 6.48968
388 1D8C SOR 6.48968
389 2RCN GDP 6.48968
390 1K6M AGS 6.48968
391 4JEJ 1GP 6.55738
392 1RJ9 GCP 6.57895
393 1KY3 GDP 6.59341
394 5O74 GDP 6.59898
395 1G6H ADP 6.61479
396 2EFE GNH 6.62983
397 5L3R GCP 6.64452
398 3PQC GDP 6.66667
399 5JCZ GDP 6.70391
400 5KDO GDP 6.75676
401 4LX0 BEF GDP 6.77966
402 1FZQ GDP 6.78466
403 3GJX GTP 6.78466
404 1SVM ATP 6.78466
405 1QHG ATP 6.78466
406 1X6V ADP 6.78466
407 2GDJ ANP 6.81818
408 1ZD9 GDP 6.91489
409 4OI4 ATP 6.95652
410 5CK5 GDP 6.96203
411 2EW1 GNP 6.96517
412 5UWS GNP 6.99301
413 6CIT GNP 6.99301
414 5DIF GNP 6.99301
415 5UWI GNP 6.99301
416 5UWW GNP 6.99301
417 5UWO GNP 6.99301
418 5UWR GNP 6.99301
419 5UWT GNP 6.99301
420 5UWP GNP 6.99301
421 5UWU GNP 6.99301
422 5UWQ GNP 6.99301
423 5UWH GNP 6.99301
424 5DHF GNP 6.99301
425 5UWJ GNP 6.99301
426 5DI9 GNP 6.99301
427 3UIE ANP 7
428 2IYL GDP 7.04225
429 1Z08 GNP 7.05882
430 1FNN ADP 7.07965
431 3KJI ADP 7.08661
432 1APZ ASP 7.0922
433 3Q85 GNP 7.10059
434 4HAT GNP 7.14286
435 4R2I ANP 7.14286
436 3EWA ANP 7.14286
437 4B47 GDP 7.16253
438 2D7C GTP 7.18563
439 2QTV GNP 7.18563
440 3BER AMP 7.22892
441 1IK4 PGH 7.23684
442 1X1R GDP 7.30337
443 4GOX A3P 7.34824
444 4MKF AP5 7.37327
445 3RC3 ANP 7.37463
446 4KBF AMP 7.37463
447 5SXS NIZ 7.37463
448 3DC4 ADP 7.37463
449 1GOJ ADP 7.37463
450 1WA5 GTP 7.38636
451 5XC5 GTP 7.38636
452 1KO8 6PG 7.42857
453 1HTW ADP 7.59494
454 2DPY ADP 7.66962
455 4RD0 GDP 7.66962
456 4V0K GDP 7.69231
457 1KAO GDP 7.78443
458 1GWN GTP 7.80488
459 1YZG GDP 7.82123
460 4DKX GDP 7.87037
461 2FNA ADP 7.9646
462 6B8B ADP 8.03213
463 1LFD GNP 8.04598
464 2GJ8 ALF GDP 8.13953
465 2QQ0 THM 8.15217
466 2QQ0 ANP 8.15217
467 2QQ0 TMP 8.15217
468 2QQ0 ADP 8.15217
469 1GOT GDP 8.21918
470 4NU0 AP5 8.29493
471 2J59 GTP 8.33333
472 4KVG GTP 8.33333
473 2OM2 GDP 8.33333
474 1S9D GDP 8.37438
475 4HDO GNP 8.38323
476 1GUA GNP 8.38323
477 3X1Z GNP 8.38323
478 3AB4 THR 8.42697
479 2OWZ CIT 8.43373
480 2Q8M AMP 8.43373
481 3A1S GDP 8.52713
482 5Z69 AGS 8.55457
483 4CVN ADP 8.55457
484 2WOJ ADP ALF 8.55457
485 6C90 ADP 8.55457
486 3DDC GNP 8.58896
487 1RRC ADP 8.63787
488 5MVR ADP 8.64198
489 4LPS GDP 8.67769
490 4J0Q GDP 8.84956
491 4YS0 ADP 8.84956
492 1R6B ADP 8.84956
493 3LRE ADP 8.84956
494 1TU3 GNP 8.86076
495 1YVD GNP 8.87574
496 1M7G AV2 9.00474
497 1M7G ADP 9.00474
498 1M7G ADX 9.00474
499 4BQS K2Q 9.09091
500 4BQS ADP 9.09091
501 2BCG GDP 9.14454
502 3CPJ GDP 9.14454
503 3CNL GNP 9.16031
504 4PU6 ASP 9.16031
505 3KC1 2T6 9.19881
506 4R98 GNH 9.22509
507 3A4M ADP 9.23077
508 1W7J ADP BEF 9.27152
509 5EE5 GTP 9.35672
510 3T5G GDP 9.39227
511 1YZQ GNP 9.41177
512 2FSH ANP 9.43953
513 6BSX E7S 9.55056
514 6BSX GDP 9.55056
515 2QN6 GDP 9.67742
516 1UAD GNP 9.71429
517 1ZC3 GNP 9.71429
518 6A4R ASP 9.73451
519 3AB3 GDP 9.7561
520 1OFH ADP 9.77011
521 2GCO GNP 9.95025
522 2GCN GDP 9.95025
523 5XKT GNP 10
524 3COB ADP 10.0295
525 4HI0 GDP 10.0503
526 4U5X GNP 10.1124
527 1Z2A GDP 10.119
528 1OXV ANP 10.3245
529 1YTM ATP 10.3245
530 2J0V GDP 10.3774
531 1L7N AF3 10.4265
532 1L7N ALF 10.4265
533 3FVQ ATP 10.585
534 5VHC BEF ADP 10.6195
535 4D0N GDP 10.8108
536 3LXR GDP 10.8108
537 6BCA GSP 10.8108
538 6BC0 GSP 10.8108
539 6BCB GSP 10.9589
540 1CXZ GSP 10.989
541 2KIN ADP 11
542 3T12 GDP ALF 11.0294
543 2OFW ADX 11.0577
544 1LVG ADP 11.1111
545 3PCR GTP 11.1111
546 2G77 GDP 11.2094
547 2G77 AF3 11.2094
548 4C4P GNP 11.215
549 1OW3 GDP 11.399
550 3NHB ADP 11.4379
551 1YQT ADP 11.5044
552 5YV5 ADP 11.5044
553 1XX6 ADP 11.5183
554 1SQS TLA 11.5702
555 2A9K GDP 11.6592
556 1G7C 5GP 11.7021
557 3B7G ANP 11.7391
558 5HPY GDP 11.8919
559 1KMQ GNP 11.9565
560 2CJW GDP 11.9792
561 2I4I AMP 12.0944
562 4ZI2 GNP 12.1053
563 4GOJ GNP 12.1693
564 5OEC GDP 12.1827
565 1YRO UDP 12.1951
566 4XOI GTP 12.2222
567 3RLF ANP 12.3894
568 2XTZ GSP 12.3894
569 2AWN ADP 12.3894
570 1TX4 ALF GDP 12.4294
571 1H65 GDP 12.5926
572 2C5L GTP 12.8205
573 2PEZ GGZ 12.8492
574 2PEZ DAT 12.8492
575 2GK6 ADP 12.9794
576 1DS6 GDP 13.0208
577 2ZEJ GDP 13.0435
578 4KFU ACP 13.2075
579 2HT6 GDP 13.2184
580 5ZXD ATP 13.2743
581 2WJG GDP 13.2979
582 1UPT GTP 13.3333
583 2O66 FLC 13.3333
584 3SBD GNP 13.369
585 2W2X GSP 13.5135
586 1VG8 GNP 13.5266
587 1VG0 GDP 13.5266
588 1D5C GDP 13.5802
589 4E03 ADP 13.5922
590 1L2T ATP 13.617
591 1QHH ATP 13.7725
592 3DOE GTP 13.9394
593 1MH1 GNP 13.9785
594 2PL3 ADP 13.9831
595 5E5U MLI 14.0152
596 2FJU GSP 14.0449
597 1G4U GDP 14.1304
598 1HE1 GDP 14.2045
599 1HE1 AF3 14.2045
600 3W5J GDP 14.2157
601 5IRC GDP 14.4279
602 5E95 GDP 14.433
603 3Q72 GNP 14.4578
604 1R0X ATP 14.6853
605 5Y6N ADP 14.7493
606 2IXE ATP 14.7601
607 1NJF ADP 14.8
608 1NJF AGS 14.8
609 3B5J 12D 14.8148
610 4WZ6 ATP 14.8276
611 2ODE ALF GDP 14.8936
612 5SZH GNP 15.0327
613 2WJH GDP 15.0602
614 2WJH FLC 15.0602
615 1VG1 GDP 15.1351
616 1VG9 GDP 15.1351
617 5LEF GTP 15.1515
618 2W83 GTP 15.5844
619 5DI3 GNP 15.5894
620 1R4A GNP 15.6863
621 5Z2M GTP 15.9091
622 1OS1 ATP 15.9292
623 1OS1 PYR 15.9292
624 4NON GDP 16.1538
625 1B0U ATP 16.7939
626 1NF3 GNP 16.9231
627 4DID GDP 17.0984
628 1ZUI SKM 17.2619
629 1A4R GDP 17.2775
630 1A4R GNH 17.2775
631 2WMO GTP 17.3684
632 1GXU 2HP 17.5824
633 4U00 ADP 17.623
634 1JJ7 ADP 17.6923
635 5UPK GNP 17.8378
636 2CK3 ANP 18
637 2CK3 ADP 18
638 4M9Q GNP 18.0617
639 1TKU 5RP 18.1373
640 4YC7 GNP 18.232
641 1B7T ADP 18.5897
642 4YMU ATP 18.75
643 2PZE ATP 18.7773
644 1KK8 BEF ADP 18.8312
645 2NGR GDP 19.3717
646 1GRN GDP 19.3717
647 4ITR GDP 19.3717
648 2VVG ADP 19.469
649 3WYG GTP 19.7368
650 2CHG ANP 19.9115
651 3IIJ ADP 20
652 5X40 ACP 20.2055
653 4XSH GSP 20.5479
654 1EK0 GNP 21.1765
655 2HV8 GTP 23.4375
656 1Z0J GTP 25.4237
657 4HDQ GNP 26.9231
658 3BC1 GNP 27.1795
659 6AIC AMP 28.0374
660 2V7Q ADP 28.7879
661 2V7Q ATP 28.7879
662 3ZS9 ADP ALF 28.9474
663 2VOH CIT 30.7692
664 3KTA AP5 35.8382
665 3ZIA ADP 37.7049
666 3ZIA ATP 37.7049
667 1XEX ATP 37.7907
668 2D7D ADP 40
669 5H67 ATP 43.7186
670 1Y63 ADP 45.6522
671 5H68 AGS 46.7647
672 3QF7 ANP 48.2192
673 1J2J GTP 48.8889
Pocket No.: 2; Query (leader) PDB : 3QKT; Ligand: ANP; Similar sites found with APoc: 17
This union binding pocket(no: 2) in the query (biounit: 3qkt.bio1) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 5CX8 TG6 2.65487
2 1QMG DMV 3.83481
3 2HF9 GSP 3.9823
4 4LRJ ANP 4.14201
5 3G5N PB2 5.01475
6 4CC6 L5Y 5.03145
7 4UXU MLK 5.04587
8 1UJ2 C5P 5.95238
9 1UJ2 ADP 5.95238
10 1FQK ALF 6.12245
11 1IGW PYR 6.78466
12 4NFE BEN 8.01688
13 3SHR CMP 9.36455
14 3PN1 IVH 9.74843
15 1M0S CIT 13.6986
16 2D24 XYS XYS 14.7493
17 1I7Q BEZ 15.544
Pocket No.: 3; Query (leader) PDB : 3QKT; Ligand: ANP; Similar sites found with APoc: 12
This union binding pocket(no: 3) in the query (biounit: 3qkt.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 5HV7 RBL 2.0649
2 4RM0 FUC NDG GAL 2.53165
3 3LN9 FLC 2.8777
4 5NM7 GLY 3.00752
5 4IJ6 SEP 3.31754
6 1OI6 TMP 3.90244
7 1GPM AMP 4.12979
8 1M5B BN1 4.56274
9 1NN5 2DT 4.65116
10 1NN5 ANP 4.65116
11 1LDN FBP 4.74684
12 1YFS ALA 5.8997
Pocket No.: 4; Query (leader) PDB : 3QKT; Ligand: ANP; Similar sites found with APoc: 4
This union binding pocket(no: 4) in the query (biounit: 3qkt.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 4WBD CIT 2.94985
2 2ZQO NGA 3.07692
3 4URN NOV 3.11111
4 2NGR AF3 19.3717
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