Receptor
PDB id Resolution Class Description Source Keywords
3QJ4 2.5 Å EC: 1.4.-.- CRYSTAL STRUCTURE OF HUMAN RENALASE (ISOFORM 1) HOMO SAPIENS FAD/NAD(P)-BINDING ROSSMANN FOLD SUPERFAMILY FLAVIN CONTAINOXIDOREDUCTASE MONOAMINE OXIDASE NAD EXTRACELLULAR OXIDOREDUCTASE
Ref.: FAD-BINDING SITE AND NADP REACTIVITY IN HUMAN RENAL NEW ENZYME INVOLVED IN BLOOD PRESSURE REGULATION J.MOL.BIOL. V. 411 463 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:401;
B:401;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
SO4 A:343;
A:344;
B:343;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3QJ4 2.5 Å EC: 1.4.-.- CRYSTAL STRUCTURE OF HUMAN RENALASE (ISOFORM 1) HOMO SAPIENS FAD/NAD(P)-BINDING ROSSMANN FOLD SUPERFAMILY FLAVIN CONTAINOXIDOREDUCTASE MONOAMINE OXIDASE NAD EXTRACELLULAR OXIDOREDUCTASE
Ref.: FAD-BINDING SITE AND NADP REACTIVITY IN HUMAN RENAL NEW ENZYME INVOLVED IN BLOOD PRESSURE REGULATION J.MOL.BIOL. V. 411 463 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3QJ4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3QJ4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3QJ4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3QJ4; Ligand: FAD; Similar sites found: 431
This union binding pocket(no: 1) in the query (biounit: 3qj4.bio1) has 39 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2GZ3 NAP 0.001336 0.41619 0.877193
2 3O9Z NAD 0.002847 0.40174 0.961538
3 1ZK7 FAD 0.00000001181 0.59259 1.46199
4 2V3A FAD 0.000000258 0.53426 1.46199
5 5DN9 NAD 0.000387 0.40954 1.46199
6 3CMC NAD 0.006156 0.40319 1.49701
7 1LTH NAD 0.00001623 0.42339 1.5674
8 1NAA ABL 0.00000002271 0.59268 1.75439
9 1NAA 6FA 0.00000001006 0.59178 1.75439
10 1N4W FAD 0.0000000298 0.57517 1.75439
11 2GMH FAD 0.0000001776 0.5448 1.75439
12 1YKJ FAD 0.00001413 0.49916 1.75439
13 1YKJ PHB 0.00001413 0.49916 1.75439
14 1KEW NAD 0.001503 0.41612 1.75439
15 1KEW TYD 0.002062 0.41032 1.75439
16 1U8X NAD 0.008043 0.40217 1.75439
17 3V1Y NAD 0.00004726 0.41828 1.78042
18 3BAZ NAP 0.0009715 0.44297 1.8018
19 1J0X NAD 0.0003598 0.4315 1.80723
20 2VOH CIT 0.03345 0.41961 1.91083
21 2VVL FAD 0.0000000000002794 0.7475 2.04678
22 1GET NAP 0.00000002699 0.60559 2.04678
23 1GET FAD 0.00000002357 0.60559 2.04678
24 4AT0 FAD 0.0000003407 0.54358 2.04678
25 4G74 UQ5 0.00001121 0.48941 2.04678
26 4G74 FAD 0.000004164 0.48674 2.04678
27 1HKU NAD 0.0002324 0.45196 2.04678
28 2Q1S NAI 0.0007386 0.4205 2.04678
29 1V8B NAD 0.0004751 0.41616 2.04678
30 4DPL NAP 0.0002594 0.40695 2.04678
31 5N53 8NB 0.001366 0.49515 2.05128
32 1KYQ NAD 0.00001194 0.4023 2.18978
33 1NVM NAD 0.0003086 0.41359 2.24359
34 2Z3Y F2N 0.00000000000008116 0.77106 2.33918
35 1Q9I TEO 0.00000001311 0.60535 2.33918
36 3E1T FAD 0.000000748 0.52591 2.33918
37 1Q9I FAD 0.00000001311 0.49324 2.33918
38 3GMB FAD 0.000005752 0.47426 2.33918
39 4XQC 13D 0.0008792 0.41885 2.33918
40 1GR0 NAD 0.0006781 0.40565 2.33918
41 4RQU NAD 0.0002795 0.40166 2.33918
42 4XQC NAD 0.002584 0.40134 2.33918
43 3WLE NAD 0.0007011 0.41071 2.34604
44 2DT5 NAD 0.0000319 0.43078 2.36967
45 1R6D NAD 0.001609 0.41674 2.37389
46 1R6D DAU 0.001726 0.4148 2.37389
47 2VYN NAD 0.00007752 0.41878 2.41692
48 1GUZ NAD 0.00009252 0.41431 2.58065
49 3ZNN 4WL 0.0000001448 0.56719 2.63158
50 3ZNN FAD 0.0000001448 0.56719 2.63158
51 2A8X FAD 0.00000006343 0.56363 2.63158
52 4M52 FAD 0.00000006302 0.56214 2.63158
53 3ICT FAD 0.000000064 0.55122 2.63158
54 2V6O FAD 0.0000009974 0.55041 2.63158
55 3ICS FAD 0.0000001008 0.54834 2.63158
56 5HSA FAS 0.0000001422 0.54817 2.63158
57 3AB1 FAD 0.0000001846 0.54261 2.63158
58 3ICR FAD 0.0000001654 0.53706 2.63158
59 5WGR FAD 0.0000006328 0.52399 2.63158
60 3KLJ FAD 0.0000001761 0.52149 2.63158
61 4BJZ P3A 0.00003693 0.48947 2.63158
62 2AQJ FAD 0.00003649 0.4812 2.63158
63 2AQJ TRP 0.00005224 0.47455 2.63158
64 1OC2 NAD 0.0008735 0.42804 2.63158
65 1OC2 TDX 0.0008735 0.42804 2.63158
66 1DLJ NAI 0.000826 0.4246 2.63158
67 4BJZ FAD 0.01134 0.42254 2.63158
68 3ICT ADP 0.0000003234 0.41368 2.63158
69 1DLJ UGA 0.002198 0.40931 2.63158
70 3ICS ADP 0.0000006804 0.40898 2.63158
71 2FR1 NDP 0.0005628 0.40178 2.63158
72 5A04 NDP 0.002444 0.41173 2.65487
73 5A04 BGC 0.003079 0.41173 2.65487
74 4J4H NAI 0.000454 0.43104 2.7027
75 4J4H 1J1 0.000454 0.43104 2.7027
76 1J49 NAD 0.00003771 0.42748 2.7027
77 4JK3 NAD 0.00002528 0.42657 2.7027
78 4YCA NDP 0.00007484 0.41173 2.72109
79 3NKS FAD 0.00000000001579 0.67504 2.72537
80 2PZM UDP 0.002016 0.40514 2.72727
81 2PZM NAD 0.002016 0.40514 2.72727
82 3F8D FAD 0.0000002946 0.56857 2.78638
83 4FWE FAD 0.0000000000001992 0.75733 2.92398
84 3AYI HCI 0.000000000004006 0.72881 2.92398
85 3AYI FAD 0.000000000003577 0.72881 2.92398
86 1GPE FAD 0.00000001554 0.58836 2.92398
87 3QVP FAD 0.00000002036 0.581 2.92398
88 3NYC IAR 0.00000008883 0.56856 2.92398
89 3NYC FAD 0.00000008883 0.56856 2.92398
90 1COY FAD 0.00000004993 0.56404 2.92398
91 3WGT FAD 0.0000001378 0.55761 2.92398
92 3WGT QSC 0.0000001577 0.5569 2.92398
93 1COY AND 0.0000003625 0.5526 2.92398
94 3CGB FAD 0.0000001069 0.54346 2.92398
95 1BW9 NAD 0.0002599 0.47839 2.92398
96 5KMS FAD 0.00000793 0.47691 2.92398
97 5KMS NAD 0.00005854 0.47274 2.92398
98 1SC6 NAD 0.0002379 0.41292 2.9703
99 3FZG SAM 0.009486 0.42563 3
100 1OMO NAD 0.00002876 0.41558 3.10559
101 1WP4 NDP 0.0001503 0.41 3.11419
102 1GZ6 NAI 0.003676 0.40597 3.1348
103 1O8B ABF 0.02046 0.4239 3.19635
104 2E5V FAD 0.00000002103 0.5805 3.21637
105 4AP3 FAD 0.0000001181 0.57395 3.21637
106 4AP3 NAP 0.0000001181 0.57395 3.21637
107 3NTA FAD 0.0000001588 0.54154 3.21637
108 3NT6 FAD 0.0000001823 0.53947 3.21637
109 5I39 FAD 0.0000001973 0.53828 3.21637
110 2NPX NAD 0.00000102 0.53727 3.21637
111 3NTD FAD 0.0000002175 0.53682 3.21637
112 5BUK FAD 0.0000007024 0.52829 3.21637
113 2NPX FAD 0.0000003054 0.52782 3.21637
114 4BV6 FAD 0.000001021 0.51827 3.21637
115 3GD4 NAD 0.000009753 0.51371 3.21637
116 3FG2 FAD 0.0000006051 0.50519 3.21637
117 3GD4 FAD 0.000009946 0.50098 3.21637
118 5JWC FAD 0.000002178 0.49272 3.21637
119 3S5W FAD 0.0000008817 0.4879 3.21637
120 3DMH SAM 0.001956 0.44336 3.21637
121 1MV8 NAD 0.00007092 0.41281 3.21637
122 3DMH GMP 0.00444 0.41015 3.21637
123 1MUU NAD 0.0001112 0.40266 3.21637
124 2O4C NAD 0.0005076 0.40032 3.21637
125 1HYH NAD 0.0001776 0.4139 3.23625
126 5UAV NDP 0.0003101 0.42233 3.41615
127 5UAV TFB 0.0003101 0.42233 3.41615
128 4MO2 FAD 0.000000001287 0.61369 3.50877
129 4MOP 2H5 0.000000005878 0.61253 3.50877
130 4MO2 FDA 0.000000001053 0.61233 3.50877
131 4MIG G3F 0.00000001495 0.59355 3.50877
132 1E1M NAP 0.0000000254 0.59091 3.50877
133 1E1M FAD 0.0000000254 0.59091 3.50877
134 4HA6 FAD 0.0000000192 0.58189 3.50877
135 5JCA FAD 0.00000001888 0.58049 3.50877
136 5JCA NDP 0.0000001931 0.56719 3.50877
137 5EB4 FAD 0.00000004837 0.56284 3.50877
138 3GDN HBX 0.0000001824 0.5573 3.50877
139 3GDN FAD 0.00000008935 0.55682 3.50877
140 4OPC FDA 0.000001962 0.55383 3.50877
141 4OPC PGT 0.000002572 0.55374 3.50877
142 2NVK FAD 0.0000001415 0.54824 3.50877
143 2XVE FAD 0.000000877 0.54183 3.50877
144 2XVF FAD 0.0000001361 0.53998 3.50877
145 1PN0 FAD 0.0000005137 0.53721 3.50877
146 1PN0 IPH 0.0000005591 0.53721 3.50877
147 4EMI NAD 0.0000014 0.53434 3.50877
148 5EZ7 FAD 0.000000304 0.53346 3.50877
149 4EMI FAD 0.0000003959 0.52785 3.50877
150 2ZXI FAD 0.0000005215 0.52011 3.50877
151 3NJ4 NAD 0.004282 0.42916 3.50877
152 3OJO NAD 0.000007332 0.42696 3.50877
153 2B4R NAD 0.00008791 0.42543 3.50877
154 3NJ4 AFX 0.01076 0.41304 3.50877
155 2B4R AES 0.0002954 0.40538 3.50877
156 1H2B NAJ 0.0006022 0.4034 3.50877
157 2ZJ1 ARJ 0.003731 0.40187 3.50877
158 2GN4 UD1 0.01727 0.4013 3.50877
159 5JY6 NAD 0.00386 0.40051 3.50877
160 2ZJ1 NAD 0.004147 0.40021 3.50877
161 5JE8 NAD 0.0001448 0.47738 3.64238
162 2Q7V FAD 0.000000001263 0.61983 3.69231
163 2VT3 ATP 0.000001541 0.40676 3.72093
164 4YSX FAD 0.00000001737 0.57832 3.7234
165 4RPL 3UC 0.000000005898 0.62923 3.80117
166 4RPL FAD 0.000000008198 0.62037 3.80117
167 4Z24 FAD 0.00000003009 0.57339 3.80117
168 3G5S FAD 0.0000003697 0.52529 3.80117
169 1DJN ADP 0.000000002917 0.52495 3.80117
170 3IHG FAD 0.0000001954 0.50044 3.80117
171 5EOW FAD 0.000001036 0.49868 3.80117
172 4NEC SAH 0.007745 0.42991 3.80117
173 3CIF NAD 0.00005258 0.42464 3.80117
174 5M67 NAD 0.001864 0.41102 3.80117
175 5M67 3D1 0.00193 0.41047 3.80117
176 3ABI NAD 0.0001999 0.41011 3.80117
177 5M67 ADE 0.00287 0.40429 3.80117
178 3CIF G3H 0.0006733 0.40223 3.80117
179 2GSD NAD 0.001209 0.40187 3.80117
180 3H9E NAD 0.0001901 0.401 3.80117
181 1E6W NAD 0.004126 0.40642 3.84615
182 4NTC FAD 0.0000002169 0.54176 3.8806
183 3LZW NAP 0.0000004643 0.54981 3.91566
184 3LZW FAD 0.0000001241 0.54523 3.91566
185 3JUC PCA 0.02725 0.41905 3.92157
186 2VDV SAM 0.002533 0.45775 4.06504
187 1ZMD FAD 0.000000008958 0.59355 4.09357
188 1KNR FAD 0.00000001071 0.58562 4.09357
189 5U8U FAD 0.0000002303 0.56758 4.09357
190 2WPF WPF 0.000001077 0.56475 4.09357
191 1BZL FAD 0.000001062 0.56358 4.09357
192 2WPF FAD 0.000001197 0.56085 4.09357
193 2GV8 FAD 0.00000002858 0.55028 4.09357
194 2GVC FAD 0.00000002049 0.55025 4.09357
195 5BVA FAD 0.0000004478 0.5352 4.09357
196 1VQW FAD 0.00000006421 0.53434 4.09357
197 4C3Y FAD 0.0000003887 0.53291 4.09357
198 4C3Y ANB 0.000001197 0.52279 4.09357
199 4EIP FAD 0.000003056 0.50832 4.09357
200 4EIP K2C 0.000003056 0.50832 4.09357
201 1ZMD NAI 0.0000001884 0.48232 4.09357
202 2X3N FAD 0.000007717 0.48044 4.09357
203 2VHW NAI 0.0003354 0.42059 4.09357
204 1RM0 NAI 0.002429 0.40419 4.09357
205 5FJN BE2 0.0000001171 0.55726 4.16667
206 5FJN FAD 0.00000008683 0.55726 4.16667
207 2HMT NAI 0.000007611 0.42426 4.16667
208 4ZRN UPG 0.003307 0.40208 4.16667
209 1GV0 NAD 0.000127 0.41374 4.19355
210 2Q1W NAD 0.0004044 0.40702 4.2042
211 1CER NAD 0.0001869 0.46908 4.22961
212 4E13 NAD 0.00002915 0.40107 4.24028
213 2F1K NAP 0.00004788 0.41924 4.30108
214 3AD8 NAD 0.000000003309 0.58126 4.38596
215 4CNK FAD 0.00000004631 0.56 4.38596
216 5MZI FYK 0.00000154 0.53281 4.38596
217 5MZI FAD 0.000001443 0.53281 4.38596
218 3Q9T FAY 0.0000002936 0.53233 4.38596
219 3AD8 FAD 0.000002454 0.53023 4.38596
220 3AD8 PYC 0.000002454 0.53023 4.38596
221 3OZ2 FAD 0.0000004669 0.52858 4.38596
222 2RGJ FAD 0.0000003745 0.50988 4.38596
223 5UAO FAD 0.00004666 0.45638 4.38596
224 1LDN NAD 0.0002587 0.40928 4.43038
225 4DMG SAM 0.004639 0.44896 4.58015
226 3FPZ AHZ 0.0006669 0.47784 4.60123
227 4YNU LGC 0.00000006403 0.57092 4.67836
228 4YNU FAD 0.00000004429 0.57069 4.67836
229 1FL2 FAD 0.00000006416 0.55687 4.67836
230 2DKH 3HB 0.0000002963 0.53384 4.67836
231 2DKH FAD 0.0000001073 0.52646 4.67836
232 5TUF TDC 0.00000348 0.51874 4.67836
233 3LXD FAD 0.0000004689 0.51517 4.67836
234 5TUF FAD 0.0000005707 0.49913 4.67836
235 1ELI PYC 0.00001635 0.47209 4.67836
236 3OND ADN 0.0008828 0.42171 4.67836
237 3OND NAD 0.0008828 0.42171 4.67836
238 2CDC XYP 0.00499 0.40596 4.67836
239 4HXY NDP 0.0004004 0.40383 4.67836
240 2CDC XYS 0.006268 0.40226 4.67836
241 2CDC NAP 0.006268 0.40226 4.67836
242 2F5Z FAD 0.00000001036 0.59133 4.6875
243 3CTY FAD 0.0000000003281 0.64595 4.70219
244 4PLG NAI 0.0005926 0.41553 4.79042
245 1DXY NAD 0.00002961 0.42429 4.8048
246 1DSS NAD 0.00002942 0.42132 4.8048
247 4ZVV NAD 0.002148 0.41607 4.81928
248 4ZVV GN0 0.002148 0.41607 4.81928
249 3UCL NAP 0.0000001989 0.57303 4.97076
250 3UCL CYH 0.0000001673 0.57275 4.97076
251 3UCL FAD 0.0000001673 0.57275 4.97076
252 2RGH FAD 0.0000009265 0.51823 4.97076
253 5TUK FAD 0.000005141 0.45387 4.97076
254 2G5C NAD 0.00006466 0.42738 4.98221
255 4M73 SAH 0.0008574 0.40752 5.04451
256 3GGO ENO 0.0005063 0.4241 5.09554
257 3GGO NAI 0.0005063 0.4241 5.09554
258 9LDB NAD 0.0001502 0.41684 5.12048
259 9LDT NAD 0.0001554 0.41634 5.12048
260 2Q0L FAD 0.0000001794 0.54464 5.14469
261 1PS9 FAD 0.00000001294 0.58453 5.26316
262 2RAB NAD 0.00000009014 0.58383 5.26316
263 2RAB FAD 0.00000001887 0.58378 5.26316
264 1WDK NAD 0.00002398 0.41456 5.26316
265 1PS9 NAP 0.0001507 0.4038 5.26316
266 1RP0 AHZ 0.00000003533 0.53605 5.28169
267 4MP8 NAD 0.00065 0.41389 5.30973
268 1SOW NAD 0.0002129 0.41549 5.4878
269 2R4J 13P 0.0000004036 0.54612 5.55556
270 2R4J FAD 0.0000004036 0.54612 5.55556
271 2BRY FAD 0.0000003106 0.51178 5.55556
272 4TXI FAD 0.0000002605 0.50909 5.55556
273 2YVF NAD 0.00001254 0.50016 5.55556
274 2YVF FAD 0.00001182 0.50016 5.55556
275 4K5S PM0 0.000006708 0.49856 5.55556
276 4K5S FAD 0.0000008991 0.49856 5.55556
277 2YVJ FAD 0.000002366 0.49789 5.55556
278 2YVJ NAI 0.0000003811 0.4421 5.55556
279 2CUL FAD 0.000000044 0.54812 5.60345
280 1YJQ NAP 0.0001688 0.42064 5.61056
281 4GUT FAD 0.0000000000001834 0.76525 5.64516
282 4GUS FAD 0.0000000000001796 0.76118 5.64516
283 4HSU FAD 0.0000000000002018 0.75939 5.64516
284 2PV7 NAD 0.00009814 0.41287 5.7047
285 2B9W FAD 0.00000000001896 0.70764 5.84795
286 4REP FAD 0.00000000001352 0.68425 5.84795
287 4X9M FAD 0.00000006608 0.55813 5.84795
288 5J7X FAD 0.000000149 0.54249 5.84795
289 2JHF NAD 0.008171 0.42219 5.84795
290 5MQ6 NDP 0.0001128 0.40419 5.84795
291 4JNA FAD 0.000001487 0.514 5.88235
292 2A92 NAI 0.0004893 0.40474 5.919
293 1KPG SAH 0.007799 0.41347 5.92335
294 4D04 NAP 0.0000002151 0.56655 6.14035
295 4D04 FAD 0.0000002151 0.56655 6.14035
296 1T26 NAI 0.0008541 0.41724 6.21118
297 3AXB PRO 0.00000007088 0.56035 6.25
298 3AXB FAD 0.00000003511 0.56035 6.25
299 2YG3 FAD 0.000000000000644 0.73248 6.43275
300 3GF4 UPG 0.000000002969 0.63031 6.43275
301 3GF4 FAD 0.000000004954 0.61807 6.43275
302 3HDY GDU 0.00000002099 0.60402 6.43275
303 3HDY FDA 0.0000000195 0.60402 6.43275
304 3HDY FAD 0.00000002418 0.60056 6.43275
305 2IID PHE 0.000000000003324 0.59434 6.43275
306 2IID FAD 0.000000000003324 0.59434 6.43275
307 3UOY NAP 0.0000001336 0.5785 6.43275
308 3UOY FAD 0.0000001336 0.5785 6.43275
309 1MO9 KPC 0.0000002774 0.57684 6.43275
310 1MO9 FAD 0.0000002671 0.5766 6.43275
311 4NTD FAD 0.0000006606 0.52018 6.43275
312 1SB8 UD2 0.00284 0.40697 6.43275
313 1SB8 NAD 0.002446 0.4059 6.43275
314 3ITJ FAD 0.0000002428 0.55019 6.50888
315 5BR7 FAD 0.000000004756 0.62668 6.61578
316 5BR7 FLC 0.00000002812 0.59813 6.61578
317 1V59 FAD 0.00000001117 0.59345 6.72515
318 2QA1 FAD 0.00000008653 0.5386 6.72515
319 1V59 NAD 0.00000006456 0.4304 6.72515
320 1BXK NAD 0.0003203 0.40202 6.72515
321 4UP3 FAD 0.0000001281 0.54813 7.00637
322 1I8T FAD 0.000000000668 0.62556 7.01754
323 4YRY FAD 0.00000001581 0.58319 7.01754
324 4YRY NAD 0.0000001428 0.56372 7.01754
325 1GTE FAD 0.0000003514 0.55648 7.01754
326 4USR FAD 0.0000006042 0.5019 7.01754
327 4USQ FAD 0.000002006 0.49129 7.01754
328 2WET FAD 0.00002087 0.47249 7.01754
329 4YUW 4JU 0.01524 0.40266 7.23684
330 4YUW S4M 0.01535 0.40213 7.23684
331 1REO FAD 0.0000000000005768 0.73172 7.30994
332 1QO8 FAD 0.0000000009999 0.62524 7.30994
333 1LVL FAD 0.0000001076 0.55554 7.30994
334 1LVL NAD 0.0000001949 0.45774 7.30994
335 3L9W AMP 0.0003479 0.40757 7.30994
336 3OFK SAH 0.0005972 0.46252 7.40741
337 1TDF FAD 0.00000003335 0.57812 7.59494
338 1TDF NAP 0.0000002804 0.56939 7.59494
339 5TS5 FAD 0.0000000000004766 0.70383 7.60234
340 1D4D FAD 0.000000001064 0.62612 7.60234
341 1YQZ FAD 0.0000002514 0.56073 7.60234
342 4J36 FAD 0.00000016 0.52028 7.60234
343 4J36 1HR 0.000001385 0.5165 7.60234
344 1UWK URO 0.002521 0.40362 7.60234
345 1UWK NAD 0.002521 0.40362 7.60234
346 5JCM FAD 0.000006763 0.51196 7.89474
347 5JCM ISD 0.000007158 0.51196 7.89474
348 5JCM NAD 0.000007158 0.51196 7.89474
349 2GAG NAD 0.00000001852 0.56972 8.08081
350 2GAG FAD 0.0000008375 0.52697 8.08081
351 2GAG FOA 0.000001525 0.51774 8.08081
352 1HDG NAD 0.0005696 0.45262 8.13253
353 3SQP FAD 0.0000009261 0.59355 8.18713
354 4II2 ATP 0.00001121 0.41612 8.43373
355 2JB2 FAD 0.000000000001591 0.71645 8.47953
356 2JB2 PHE 0.00000000000186 0.71645 8.47953
357 2HQM FAD 0.00000001683 0.58224 8.47953
358 1Y8Q ATP 0.00002395 0.41962 8.47953
359 3QFA FAD 0.0000002063 0.54407 8.62069
360 1RYI FAD 0.0000003175 0.53598 8.63874
361 1RYI GOA 0.004281 0.42226 8.63874
362 1YY5 FAD 0.0000000000001079 0.769 8.77193
363 1RSG FAD 0.000000000000194 0.75541 8.77193
364 3WE0 FAD 0.000000000002543 0.71839 8.77193
365 2CDU FAD 0.0000005807 0.51493 8.77193
366 4RSL FAD 0.000004453 0.4854 8.77193
367 2CDU ADP 0.00000007774 0.45328 8.77193
368 1H82 FAD 0.0000000000003524 0.77078 9.06433
369 1H82 GZZ 0.0000000000006039 0.77078 9.06433
370 2C7G FAD 0.00000005653 0.58088 9.06433
371 2C7G ODP 0.0000000522 0.58086 9.06433
372 5VN0 FAD 0.000001718 0.50585 9.06433
373 5VN0 NAI 0.00002441 0.40604 9.06433
374 5O4J SAH 0.0006725 0.40603 9.12409
375 5O4J 9KH 0.0006725 0.40603 9.12409
376 5O4J PJL 0.0007861 0.40061 9.12409
377 5TTJ FAD 0.0000000000005039 0.73375 9.18367
378 5MBX SP5 0.0000000000001426 0.78326 9.35672
379 5MBX FAD 0.0000000000001426 0.78326 9.35672
380 2IXB NAD 0.0003724 0.40597 9.35672
381 2IXB A2G 0.001554 0.40384 9.35672
382 1E6E FAD 0.000000003994 0.58766 9.375
383 1VDC FAD 0.00000009965 0.56264 9.60961
384 3VPH OXM 0.0005979 0.40953 9.67742
385 3LAD FAD 0.0000000243 0.57665 9.94152
386 4JDR FAD 0.00000003186 0.57086 9.94152
387 2RGO FAD 0.0000003849 0.52474 9.94152
388 2IVD FAD 0.0000000000008156 0.71293 10.2339
389 2EV9 NAP 0.0004664 0.40324 10.2662
390 2EV9 SKM 0.0004664 0.40324 10.2662
391 4EMJ FAD 0.0000006384 0.52229 10.2804
392 1O94 ADP 0.00000000623 0.52208 10.6061
393 2VVM FAD 0.000000000000367 0.74097 10.8187
394 3K7M FAD 0.000000000006328 0.72161 10.8187
395 4U8P FDA 0.000000002117 0.64589 10.8187
396 4U8P UDP 0.000000002445 0.64589 10.8187
397 3T31 FAD 0.000003867 0.51285 10.8187
398 3T31 DCQ 0.000004425 0.51285 10.8187
399 2V3B FAD 0.0000003369 0.52641 10.9091
400 3WV8 ATP 0.00003731 0.40897 11.0092
401 1XHC FAD 0.0000002226 0.52893 11.4035
402 4D7E FAD 0.000004048 0.48651 11.4035
403 2NAD NAD 0.0009243 0.4036 11.4035
404 5J60 FAD 0.00000004592 0.56363 11.5625
405 3HAD NAD 0.001419 0.41526 11.6883
406 5G3U FDA 0.0000000000002268 0.74322 11.6959
407 5G3U ITW 0.000000000001281 0.73104 11.6959
408 4DSG UDP 0.000000001778 0.64117 11.6959
409 4DSG FAD 0.000000001778 0.64117 11.6959
410 2HJR APR 0.00003829 0.4082 11.6959
411 2I3G NAP 0.0004305 0.40374 11.6959
412 3B1F NAD 0.000006401 0.42818 11.7241
413 1D1T NAD 0.0003972 0.40597 12.2807
414 1LSS NAD 0.000008704 0.41675 12.8571
415 5ODQ FAD 0.0000001376 0.55024 12.8655
416 1Q1R FAD 0.000001089 0.50943 12.8655
417 4IV9 FAD 0.0000000000006855 0.73153 13.7427
418 4TM3 FAD 0.00001908 0.49864 14.3275
419 3CGD COA 0.0000005997 0.56231 15.2047
420 3CGD FAD 0.0000005997 0.56231 15.2047
421 3CGD NAD 0.0000005997 0.56231 15.2047
422 4J56 FAD 0.00000001257 0.59001 16.0819
423 1UXG NAD 0.0003403 0.4266 16.1812
424 1JNR FAD 0.0000005165 0.56214 16.6667
425 2Y6Q I7T 0.000006423 0.49684 17.8363
426 2Y6Q FAD 0.0000007151 0.4964 17.8363
427 1FEC FAD 0.0000004589 0.53761 19.5906
428 4E5N NAD 0.0002005 0.41386 23.6364
429 3RNM FAD 0.000000007387 0.5965 29.3103
430 4ZCC FAD 0.0000000000000161 0.81155 36.0119
431 4ZCC NAI 0.0000000000000161 0.81155 36.0119
Pocket No.: 2; Query (leader) PDB : 3QJ4; Ligand: FAD; Similar sites found: 6
This union binding pocket(no: 2) in the query (biounit: 3qj4.bio2) has 39 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2NU8 COA 0.002463 0.40009 2.43056
2 1JG3 ADN 0.0003474 0.40011 4.25532
3 1I0Z NAI 0.000368 0.40157 6.60661
4 3VPH NAD 0.0006372 0.40204 9.67742
5 1C0I BE2 0.01655 0.40082 10.8187
6 1C0I FAD 0.01655 0.40082 10.8187
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