Receptor
PDB id Resolution Class Description Source Keywords
3QFJ 2.29 Å NON-ENZYME: IMMUNE THE COMPLEX BETWEEN TCR A6 AND HUMAN CLASS I MHC HLA-A2 WITH MODIFIED TAX (Y5F) PEPTIDE HOMO SAPIENS TAX PEPTIDE NONAPEPTIDE MHC CLASS I HLA-A2 TCR A6 CROSSREACTIVITY Y5F MUTATION IMMUNE SYSTEM
Ref.: DISPARATE DEGREES OF HYPERVARIABLE LOOP FLEXIBILITY T-CELL RECEPTOR CROSS-REACTIVITY, SPECIFICITY, AND MECHANISM. J.MOL.BIOL. V. 414 385 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:276;
A:277;
B:100;
B:101;
B:102;
C:10;
D:207;
E:247;
E:248;
E:249;
E:250;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
LEU LEU PHE GLY PHE PRO VAL TYR VAL C:1;
Valid;
none;
submit data
1054.3 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3QFJ 2.29 Å NON-ENZYME: IMMUNE THE COMPLEX BETWEEN TCR A6 AND HUMAN CLASS I MHC HLA-A2 WITH MODIFIED TAX (Y5F) PEPTIDE HOMO SAPIENS TAX PEPTIDE NONAPEPTIDE MHC CLASS I HLA-A2 TCR A6 CROSSREACTIVITY Y5F MUTATION IMMUNE SYSTEM
Ref.: DISPARATE DEGREES OF HYPERVARIABLE LOOP FLEXIBILITY T-CELL RECEPTOR CROSS-REACTIVITY, SPECIFICITY, AND MECHANISM. J.MOL.BIOL. V. 414 385 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 3QFJ - LEU LEU PHE GLY PHE PRO VAL TYR VAL n/a n/a
70% Homology Family (30)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 67 families.
1 4JFF Kd = 600 pM GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
2 4JFD Kd = 36 uM GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
3 2P5E - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
4 2BNQ Kd = 5 uM SER LEU LEU MET TRP ILE THR GLN VAL n/a n/a
5 2BNR Kd = 13.3 uM SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
6 2PYE - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
7 2P5W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
8 3VXM - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
9 5JZI - LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL n/a n/a
10 5HHM - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
11 2VLK - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
12 2VLJ - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
13 1OGA - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
14 2VLR - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
15 5ISZ Kd = 27 nM GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
16 3QFJ - LEU LEU PHE GLY PHE PRO VAL TYR VAL n/a n/a
17 5EU6 - TYR LEU GLU PRO GLY PRO VAL THR VAL n/a n/a
18 1BD2 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
19 6BJ3 Kd = 17 uM ILE PRO LEU THR GLU GLU ALA GLU LEU n/a n/a
20 5C0B - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
21 5C07 - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
22 5C0C - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
23 5BS0 Kd = 76.7 nM GLU SER ASP PRO ILE VAL ALA GLN TYR n/a n/a
24 6D78 - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
25 3QDJ - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
26 1MI5 Kd ~ 10 uM PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
27 3VXS - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
28 3VXR - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
29 4G9F - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
30 4G8G - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
50% Homology Family (44)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 45 families.
1 4JFF Kd = 600 pM GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
2 4JFD Kd = 36 uM GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
3 2F53 - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
4 2P5E - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
5 2BNQ Kd = 5 uM SER LEU LEU MET TRP ILE THR GLN VAL n/a n/a
6 2BNR Kd = 13.3 uM SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
7 2PYE - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
8 2P5W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
9 3VXM - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
10 5JZI - LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL n/a n/a
11 5HHM - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
12 2VLK - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
13 2VLJ - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
14 1OGA - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
15 2VLR - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
16 5ISZ Kd = 27 nM GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
17 3QFJ - LEU LEU PHE GLY PHE PRO VAL TYR VAL n/a n/a
18 5IVX Kd ~ 0.54 uM ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
19 5EU6 - TYR LEU GLU PRO GLY PRO VAL THR VAL n/a n/a
20 1BD2 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
21 6BJ8 - VAL PRO LEU THR GLU ASP ALA GLU LEU n/a n/a
22 6BJ3 Kd = 17 uM ILE PRO LEU THR GLU GLU ALA GLU LEU n/a n/a
23 5JHD Kd = 37 nM GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
24 4NQD - 2LJ C12 H20 N4 O6 CC/C=N/C1=....
25 4LCW - 1VY C12 H16 N4 O7 CC1=C(N(C2....
26 4L4V Kd = 1.65 uM 1VY C12 H16 N4 O7 CC1=C(N(C2....
27 2JCC - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
28 2UWE - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
29 1LP9 - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
30 5C09 - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
31 5C0A - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
32 5C08 - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
33 5C0B - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
34 5C07 - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
35 5C0C - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
36 5BS0 Kd = 76.7 nM GLU SER ASP PRO ILE VAL ALA GLN TYR n/a n/a
37 6D78 - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
38 3QDJ - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
39 1MI5 Kd ~ 10 uM PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
40 3VXS - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
41 3VXR - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
42 1MWA - GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
43 4G9F - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
44 4G8G - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LEU LEU PHE GLY PHE PRO VAL TYR VAL; Similar ligands found: 181
No: Ligand ECFP6 Tc MDL keys Tc
1 LEU LEU PHE GLY TYR PRO VAL TYR VAL 1 1
2 LEU LEU PHE GLY PHE PRO VAL TYR VAL 1 1
3 LEU PHE GLY TYR PRO VAL TYR VAL 0.931624 1
4 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.888 0.968254
5 LEU LEU TYR GLY PHE VAL ASN TYR VAL 0.653846 0.75
6 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.607843 0.953125
7 ARG THR PHE SER PRO THR TYR GLY LEU 0.602649 0.847222
8 LEU LEU TYR GLY PHE VAL ASN TYR ILE 0.59854 0.738462
9 ALA LEU TRP GLY PHE PHE PRO VAL LEU 0.588235 0.890625
10 GLU TYR LEU GLY LEU ASP VAL PRO VAL 0.575342 0.951613
11 ILE PRO ALA TYR GLY VAL LEU THR ILE 0.567568 0.907692
12 TYR LEU LYS GLU PRO VAL HIS GLY VAL 0.559748 0.923077
13 ALA LEU TRP GLY PHE VAL PRO VAL LEU 0.55414 0.890625
14 ARG TYR PRO LEU THR PHE GLY TRP 0.550296 0.835616
15 TYR LEU GLY GLY PRO ASP PHE PRO THR ILE 0.54375 0.910448
16 PHE ALA PRO GLY ASN TYR PRO ALA LEU 0.542484 0.910448
17 PHE LEU PRO SER ASP PHE PHE PRO SER VAL 0.541667 0.865672
18 PHE ALA PRO GLY PHE PHE PRO TYR LEU 0.54 0.9375
19 TYR LEU GLU PRO GLY PRO VAL THR VAL 0.536424 0.893939
20 LYS PRO ILE VAL VAL LEU HIS GLY TYR 0.524691 0.909091
21 LEU GLY TYR GLY PHE VAL ASN TYR ILE 0.521127 0.738462
22 MET VAL TRP GLY PRO ASP PRO LEU TYR VAL 0.520231 0.871429
23 HIS SER ILE THR TYR LEU LEU PRO VAL 0.5125 0.830986
24 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.5125 0.884058
25 TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA 0.512346 0.923077
26 ILE GLY PRO GLY ARG ALA PHE TYR VAL 0.512346 0.897059
27 TYR LEU GLU PRO ALA PRO VAL THR ALA 0.510067 0.865672
28 ARG PHE PRO LEU THR PHE GLY TRP 0.508876 0.808219
29 TYR LEU GLU PRO GLY PRO VAL THR ALA 0.506494 0.893939
30 TYR LEU ALA PRO GLY PRO VAL THR ALA 0.503356 0.880597
31 VAL ORN LEU DPN PRO VAL ORN LEU DPN PRO 0.5 0.857143
32 DHI PRO PHE HIS LEU LEU VAL TYR 0.5 0.907692
33 LEU ASN PHE PRO ILE SER PRO 0.5 0.811594
34 PRO ARG GLY TYR PRO GLY GLN VAL 0.5 0.920635
35 PHE GLN PRO GLN ASN GLY GLN PHE ILE 0.493506 0.833333
36 TYR MET PHE PRO ASN ALA PRO TYR LEU 0.490566 0.84507
37 THR THR ALA PRO PHE LEU SER GLY LYS 0.490446 0.808824
38 ARG TYR PRO LEU THR LEU GLY TRP CYS PHE 0.48913 0.813333
39 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.488372 0.821918
40 LYS LEU PRO ALA GLN PHE TYR ILE LEU 0.487805 0.968254
41 PHE ALA PRO GLY ASN TYR PRO 0.486486 0.865672
42 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.486486 0.8
43 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.486339 0.810811
44 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.48503 0.810811
45 PHE LEU ARG GLY ARG ALA TYR VAL LEU 0.483871 0.735294
46 LYS LEU TYR GLN ASN PRO THR THR TYR ILE 0.481707 0.882353
47 ILE LEU LYS GLU PRO VAL HIS GLY VAL 0.481481 0.818182
48 GLN LEU SER PRO PHE PRO PHE ASP LEU 0.480519 0.878788
49 SER ASP ILE LEU PHE PRO ALA ASP SER 0.48 0.820895
50 ARG MET PHE PRO ASN ALA PRO TYR LEU 0.47929 0.792208
51 ARG SEP PRO VAL PHE SER 0.477707 0.675325
52 PHE ALA PRO GLY ASN TYI PRO ALA LEU 0.475309 0.847222
53 LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE 0.475 0.724638
54 LEU TYR LEU VAL CYS GLY GLU ARG VAL 0.474359 0.695652
55 PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU 0.473988 0.880597
56 GLN ASN TYR PRO ILE VAL GLN 0.473333 0.892308
57 ARG PHE PRO LEU THR PHE GLY TRP CYS PHE 0.472527 0.786667
58 PHE GLU ALA ILE PRO ALA GLU TYR LEU 0.471698 0.967742
59 SER ILE TYR PHE TPO PRO GLU LEU TYR ASP 0.47093 0.824324
60 ASP PHE GLU GLU ILE PRO GLY GLU TYR LEU 0.46988 0.953125
61 LEU SER SER PRO VAL THR LYS SER PHE 0.467949 0.80597
62 LEU PRO SER PHE GLU THR ALA LEU 0.467532 0.848485
63 ILE GLY PRO GLY ARG ALA PHE TYR THR 0.467066 0.869565
64 ILE SER TYR GLY ASN ASP ALA LEU MET PRO 0.467066 0.819444
65 GLN ASN GLY PTR VAL ASN PRO THR TYR 0.464968 0.821918
66 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.463576 0.757143
67 SER SER TYR ARG ARG PRO VAL GLY ILE 0.462963 0.783784
68 TYR PRO PHE PHE NH2 0.462121 0.885246
69 ASN ARG PRO VAL TYR ILE PRO ARG PRO PRO 0.462025 0.814286
70 SER LEU PHE HIS 22G THR PRO 0.461538 0.857143
71 GLY TYR GLU ASN PRO THR TYR LYS PHE PHE 0.461078 0.865672
72 ILE LEU GLY PRO PRO GLY SER VAL TYR 0.459627 0.867647
73 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.459627 0.72973
74 LYS PRO ILE VAL GLN TYR ASP ASN PHE 0.458333 0.910448
75 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.457317 0.907692
76 ILE GLY PRO GLY ARG ALA PHE TYR THR ILE 0.456647 0.84507
77 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.45625 0.679487
78 ASP ASN ARG LEU GLY LEU VAL TYR GLN PHE 0.455882 0.737705
79 GLY TYR GLN ASP TYR GLU PRO GLU ALA 0.455172 0.887097
80 ARG PRO MET THR TYR LYS GLY ALA LEU 0.454545 0.776316
81 ASN GLY TYR GLU ASN PRO THR TYR LYS 0.454545 0.865672
82 PHE ALA PRO GLY ASN TYR PRO ALA TRP 0.454023 0.855072
83 ILE GLY PRO GLY ARG ALA PHE TYR ALA 0.451807 0.882353
84 TYR PRO ASN VAL ASN ILE HIS ASN PHE 0.451807 0.869565
85 VAL TYR PRO IAS HIS ALA 0.45098 0.865672
86 ACE GLY PHE GLY VAL VAL PRO SER PHE TYR 0.449664 0.830769
87 ARG PRO MET THR PHE LYS GLY ALA LEU 0.448864 0.736842
88 ARG GLN PHE GLY PRO ASP PHE PRO THR ILE 0.448276 0.794521
89 GLY LEU LEU GLY SEP PRO VAL ARG ALA 0.446541 0.675325
90 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.446429 0.739726
91 SER SER LEU GLU ASN PHE ALA ALA TYR VAL 0.445161 0.701493
92 ASP PHE GLU GLU ILE PRO GLY GLU TYS LEU 0.443787 0.75
93 ASN TYR THR PRO GLY PRO GLY THR ARG PHE 0.442529 0.808219
94 VAL PRO LEU ARG PRO MET THR TYR 0.442424 0.763158
95 GLY ALA GLU VAL PHE TYR VAL ASP GLY ALA 0.439189 0.761905
96 GLY ILE LEU GLY LEU VAL PHE THR LEU 0.438356 0.661538
97 PHE LEU ARG GLY ARG ALA TYR GLY LEU 0.437909 0.735294
98 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.436464 0.797297
99 ALA PHE ARG ILE PRO LEU THR ARG 0.435583 0.753425
100 MET LEU TRP GLY TYR LEU GLN TYR VAL 0.435583 0.80597
101 TRP GLU TYR ILE PRO ASN VAL 0.435294 0.882353
102 PHE ASN PHE PRO GLN ILE THR 0.435065 0.835821
103 ASN TYR THR PRO GLY PRO GLY ILE ARG PHE 0.435028 0.810811
104 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.434066 0.776316
105 LEU TYR LEU VAL CYS GLY GLU ARG GLY 0.433962 0.695652
106 ILE THR ASP GLN VAL PRO PHE SER VAL 0.432927 0.835821
107 VAL MET ALA PRO ARG THR LEU PHE LEU 0.431953 0.723684
108 TYR PRO TYR ASP VAL PRO ASP TYR ALA 0.430464 0.921875
109 ASP VAL GLN THR GLY ARG ARG PRO TYR GLU 0.430233 0.805556
110 PHE PRO THR LYS ASP VAL ALA LEU 0.429448 0.848485
111 ARG PRO PRO ILE PHE ILE ARG ARG LEU 0.429448 0.771429
112 TYR SEP PRO THR SEP PRO SER 0.428571 0.743243
113 GLU THR PHE TYR VAL ASP GLY 0.427586 0.738462
114 SER PRO ILE VAL PRO SER PHE ASP MET 0.426829 0.777778
115 PHE ASN ARG PRO VAL 0.426667 0.757143
116 TYR GLY GLY PHE LEU 0.426471 0.803279
117 PHE PRO ARG PRO TRP LEU HIS GLY LEU 0.42623 0.791667
118 LEU PRO PHE GLU LYS SER THR VAL MET 0.426035 0.788732
119 LYS TYR TYR SER ILE ILE PRO HIS SER ILE 0.425926 0.830986
120 TYR TYR SER ILE ILE PRO HIS SER ILE 0.425926 0.830986
121 LYS THR PHE PRO PRO THR GLU PRO LYS 0.425926 0.833333
122 PHE LEU SER TYR LYS 0.425532 0.753846
123 ARG LEU TYR HIS SEP LEU PRO ALA 0.425287 0.725
124 GLU ALA ASP PRO THR GLY HIS SER TYR 0.425287 0.828571
125 GLY ALA GLU THR PHE TYR VAL ASP GLY ALA 0.424837 0.727273
126 ACE LEU TYR ALA SER SER ASN PRO ALA PTR 0.424242 0.813333
127 GLU PTR LEU GLY LEU ASP VAL PRO VAL 0.424242 0.822581
128 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.422619 0.783784
129 DVA DPR GLY DSN DGN DHI DTY DAS DSN 0.422619 0.842857
130 ASP ASP ASP MET GLY PHE GLY LEU PHE ASP 0.422222 0.693548
131 ASP ASP MET GLY PHE GLY LEU PHE ASP 0.422222 0.693548
132 GLU PRO VAL GLU THR THR ASP TYR 0.422078 0.861538
133 LYS PRO PHE PTR VAL ASN VAL NH2 0.420732 0.794521
134 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.420455 0.733333
135 PRO PRO ALA TYR PRO PRO PRO PRO VAL PRO 0.42 0.875
136 ALA VAL ALA PHE TYR ILE PRO ASP GLN ALA 0.42 0.935484
137 ASN ASP TRP LEU LEU PRO SER TYR 0.41954 0.871429
138 PHE LEU TRP GLY PRO ARG ALA LEU VAL 0.418994 0.814286
139 PRO SER TYR SEP PRO THR SEP PRO SER 0.417722 0.743243
140 ARG TYR GLY PHE VAL ALA ASN PHE 0.417722 0.7
141 GLY SER TYR LEU VAL THR SER VAL 0.417266 0.666667
142 GLY LEU MET TRP LEU SER TYR PHE VAL 0.417178 0.746479
143 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.416667 0.893939
144 GLU SER ASP PRO ILE VAL ALA GLN TYR 0.416667 0.880597
145 SER SER GLY LYS VAL PRO LEU SER 0.416107 0.791045
146 ASN LEU VAL PRO VAL VAL ALA THR VAL 0.416107 0.80303
147 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.41573 0.72973
148 TYR TYR SER ILE ALA PRO HIS SER ILE 0.415663 0.805556
149 ILE MET ASP GLN VAL PRO PHE SER VAL 0.414201 0.774648
150 ARG PRO PRO GLY PHE SER PRO PHE ALA 0.413174 0.75
151 ARG GLY TYR VAL TYR GLN GLY LEU 0.412903 0.746269
152 THR GLU ASN LEU TYR PHE GLN SER GLY THR 0.4125 0.746269
153 GLN VAL PRO SER ASP PRO TYR ASN TYR 0.4125 0.852941
154 LEU PRO PHE GLU ARG ALA THR VAL MET 0.412429 0.746667
155 ARG VAL SER PRO SER THR SER TYR THR PRO 0.412162 0.848485
156 ASP PHE GLU GLU ILE PRO GLU GLU TYS LEU 0.411111 0.759494
157 TRP ASP ILE PRO PHE 0.410072 0.825397
158 TRP MET ASP PHE ASP ASP ASP ILE PRO PHE 0.410072 0.825397
159 VAL SER GLN ASN TYR PRO ILE VAL GLN ASN 0.409938 0.852941
160 GLY ASN TYR SER PHE TYR ALA LEU 0.409722 0.701493
161 ACE PHE HIS PRO ALA NH2 0.409722 0.757576
162 CYS VAL ASN GLY SER CYS PHE THR VAL 0.407895 0.617647
163 TYR MET ASP PHE ASP ASP ASP ILE PRO PHE 0.407692 0.806452
164 ACE TYR PRO ILE GLN GLU THR 0.407643 0.890625
165 THR PRO PRO SER PRO PHE 0.407143 0.80303
166 THR PRO ASP TYR PHE LEU 0.407143 0.887097
167 GLU THR LEU LEU ASP LEU ASP PHE ASP PRO 0.406667 0.861538
168 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.40625 0.783784
169 ASP TYR ILE ASN THR ASN VAL LEU PRO 0.40625 0.865672
170 ASN ARG PRO VAL TYR ILE PRO PRO PRO PRO 0.405229 0.890625
171 GLY GLY CYS PHE SER LYS PRO LYS MYR 0.404624 0.746479
172 ARG GLY PRO GLY CYS ALA PHE VAL THR ILE 0.404494 0.767123
173 GLU PHE SER PRO 0.404412 0.796875
174 GLU GLN TYR LYS PHE TYR SER VAL 0.403974 0.742424
175 SER TYR SEP PRO THR SEP PRO SEP TYR SER 0.403846 0.716216
176 ACE GLU HIS PHE ILE VAL PRO ASP LEU TYR 0.402367 0.80597
177 GLY ILE LEU GLY PHE VAL PHE THR LEU 0.401316 0.676923
178 ASP ILE ALA TYR TYR THR SER GLU PRO 0.401274 0.895522
179 LYS VAL LEU PHE LEU ASP GLY 0.4 0.709677
180 ASN LEU VAL PRO THR VAL ALA THR VAL 0.4 0.80303
181 GLU ASN LEU TYR PHE GLN 0.4 0.71875
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3QFJ; Ligand: LEU LEU PHE GLY PHE PRO VAL TYR VAL; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3qfj.bio1) has 43 residues
No: Leader PDB Ligand Sequence Similarity
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