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Receptor
PDB id Resolution Class Description Source Keywords
3QFA 2.2 Å EC: 1.8.1.9 CRYSTAL STRUCTURE OF THE HUMAN THIOREDOXIN REDUCTASE-THIORED COMPLEX HOMO SAPIENS PROTEIN-PROTEIN COMPLEX ROSSMANN FOLD THIOREDOXIN FOLD HOPYRIDINE NUCLEOTIDE DISULFIDE OXIDOREDUCTASE ELECTRON TRANOXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF THE HUMAN THIOREDOXIN REDUCTASE-THIOREDOXIN COMPLEX NAT COMMUN V. 2 383 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:600;
B:600;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
GOL A:801;
A:802;
A:803;
A:804;
B:804;
D:803;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3QFA 2.2 Å EC: 1.8.1.9 CRYSTAL STRUCTURE OF THE HUMAN THIOREDOXIN REDUCTASE-THIORED COMPLEX HOMO SAPIENS PROTEIN-PROTEIN COMPLEX ROSSMANN FOLD THIOREDOXIN FOLD HOPYRIDINE NUCLEOTIDE DISULFIDE OXIDOREDUCTASE ELECTRON TRANOXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF THE HUMAN THIOREDOXIN REDUCTASE-THIOREDOXIN COMPLEX NAT COMMUN V. 2 383 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 3QFA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 3QFA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4J57 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 4J56 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 3QFA - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3QFA; Ligand: FAD; Similar sites found with APoc: 962
This union binding pocket(no: 1) in the query (biounit: 3qfa.bio1) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 5U5G NAP 1.69492
2 5U5G 7VD 1.69492
3 3NYC FAD 1.72414
4 3NYC IAR 1.72414
5 5Y77 FAD 1.72414
6 4Z0H NAD 1.79641
7 6GKV SAH 1.9943
8 4ZGS NAD 2.07254
9 3V1Y NAD 2.07715
10 4XB2 NDP 2.08955
11 4XB2 HSE 2.08955
12 4WXJ GLU 2.23048
13 3DXY SAM 2.29358
14 1JG3 ADN 2.31214
15 4GGL CJC 2.32558
16 3G6M CFF 2.58621
17 3NJ4 NAD 2.58621
18 4P5E N6P 2.58621
19 6F3M NAD 2.58621
20 3NJ4 AFX 2.58621
21 6F3N NAD 2.58621
22 6F3N ADN 2.58621
23 2Q28 ADP 2.65957
24 5BSZ SAH 2.8
25 1PL6 NAD 2.80899
26 1PL6 572 2.80899
27 2F1K NAP 2.86738
28 2YY7 NAD 2.88462
29 4USR FAD 2.89017
30 2O4C NAD 2.89474
31 5Z20 NAI 2.89855
32 4ZCC FAD 3.08285
33 4ZCC NAI 3.08285
34 4R5M NAP 3.19149
35 5KKA 6V0 3.20513
36 5HV7 RBL 3.21101
37 3G89 SAM 3.21285
38 5A96 GTP 3.21285
39 4URF 1PS 3.22581
40 4MDH NAD 3.29341
41 5NUF NAD 3.31325
42 5NUE NAD 3.31325
43 4NBT NAD 3.33333
44 5DWQ SFG 3.4384
45 5DXA SFG 3.4384
46 5DX1 SFG 3.4384
47 5DX8 SFG 3.4384
48 5DX0 SFG 3.4384
49 1MV8 NAD 3.44037
50 5BUK FAD 3.44828
51 2B9W FAD 3.44828
52 4BJZ P3A 3.44828
53 4BJZ FAD 3.44828
54 3UCL NAP 3.44828
55 3UCL CYH 3.44828
56 3UCL FAD 3.44828
57 2R4J FAD 3.44828
58 2R4J 13P 3.44828
59 3VYW SAM 3.44828
60 1YKF NAP 3.44828
61 2EFJ SAH 3.44828
62 5M60 BGC 3.44828
63 5W7M SAH 3.44828
64 2VAR AMP 3.46821
65 3OND NAD 3.48361
66 3OND ADN 3.48361
67 4M37 SAH 3.49854
68 4E13 NAD 3.53357
69 4XDA ADP 3.55987
70 1KJ8 GAR 3.58056
71 4O0L NDP 3.63636
72 4GKV NAD 3.66089
73 2EG5 SAH 3.76344
74 3BXO SAM 3.76569
75 5ZI2 NAD 3.76812
76 5ZI2 ADP 3.76812
77 1KOL NAD 3.76884
78 5TC4 NAD 3.79747
79 2IXB NAD 3.82883
80 2IXB A2G 3.82883
81 1KZL CRM 3.84615
82 1Q19 SSC 3.85356
83 1RM4 NDP 3.85757
84 4JK3 NAD 3.861
85 4J4H NAI 3.861
86 4J4H 1J1 3.861
87 1J0X NAD 3.91566
88 3I53 SAH 3.91566
89 1YJQ NAP 3.9604
90 2I3G NAP 3.97727
91 3FPZ AHZ 3.98773
92 2D2I NAP 4.04624
93 2CDC NAP 4.09836
94 2CDC XYP 4.09836
95 2CDC XYS 4.09836
96 4L9Z OXL 4.12979
97 1SAY PYR 4.15512
98 3DCM SAM 4.16667
99 5MTE BB2 4.23892
100 4KQW NAP 4.28571
101 4BV6 FAD 4.31034
102 1Q9I TEO 4.31034
103 1Q9I FAD 4.31034
104 4REP FAD 4.31034
105 4U8P UDP 4.31034
106 5WGR FAD 4.31034
107 4U8P FDA 4.31034
108 5OC1 FAD 4.31034
109 4D04 FAD 4.31034
110 4D04 NAP 4.31034
111 3WGT QSC 4.31034
112 3WGT FAD 4.31034
113 1DSS NAD 4.31034
114 3U31 NAD 4.31034
115 6HKE LMR 4.31034
116 6HKE MLT 4.31034
117 3A4T SFG 4.31034
118 5KVA SAM 4.31034
119 1EJ4 M7G 4.31034
120 4L8V NAP 4.31034
121 3VSS FRU 4.31034
122 1ZGS XMM 4.31034
123 1R37 NAD 4.31034
124 1IZC PYR 4.31034
125 2CBZ ATP 4.31034
126 6BWL NAD 4.31034
127 1ZH8 NAP 4.41176
128 1KNR FAD 4.4316
129 1I8T FAD 4.4316
130 3GD4 NAD 4.50098
131 3GD4 FAD 4.50098
132 4J1Q NDP 4.52586
133 2FLI DX5 4.54545
134 2IVD FAD 4.60251
135 2CH5 NAG 4.61095
136 6F97 FAD 4.62428
137 4OBW SAM 4.66926
138 5E4R NAP 4.69388
139 5W3K 9TY 4.70588
140 5W3K NDP 4.70588
141 4H2D FMN 4.81696
142 5APG EEM 4.81696
143 1WP4 NDP 4.84429
144 2CVZ NDP 4.84429
145 6DUB SAH 4.95496
146 1UAY ADN 4.95868
147 1GEG NAD 5.07812
148 1RSG FAD 5.17241
149 5GSN NAP 5.17241
150 5GSN FAD 5.17241
151 2IID FAD 5.17241
152 2IID PHE 5.17241
153 5ZYN FAD 5.17241
154 5TS5 FAD 5.17241
155 5TTJ FAD 5.17241
156 5GSN MMZ 5.17241
157 2HMT NAI 5.17241
158 1RYI GOA 5.17241
159 1RYI FAD 5.17241
160 5NMX NAP 5.17241
161 2GV8 FAD 5.17241
162 2GVC FAD 5.17241
163 1VQW FAD 5.17241
164 5NMX FAD 5.17241
165 3GFB NAD 5.17241
166 5EES NAP 5.17241
167 6BQ6 TER 5.17241
168 4KOA NDP 5.17241
169 2GV8 NDP 5.17241
170 2B4R AES 5.17241
171 3GU3 SAH 5.17241
172 1X7D NAD 5.17241
173 2B4R NAD 5.17241
174 1NVT NAP 5.17241
175 3Q3C NAD 5.17241
176 1GZ4 ATP 5.17241
177 1SQF SAM 5.17241
178 4CJX NAP 5.17241
179 1H2B NAJ 5.17241
180 1KEV NDP 5.17241
181 3PT9 SAH 5.17241
182 5A1S FLC 5.17241
183 1XF1 CIT 5.17241
184 2OFD NGA 5.17241
185 4NOS ITU 5.17241
186 2DPM SAM 5.17241
187 4HXY NDP 5.17241
188 1VKO NAD 5.17241
189 1U1I NAD 5.17241
190 3O7W SAM 5.17241
191 5YAP NAI 5.17241
192 5YAP 8S0 5.17241
193 2VTD LKM 5.17241
194 2JJQ SAH 5.17647
195 5MZI FYK 5.20607
196 5MZI FAD 5.20607
197 3A25 SAM 5.31561
198 1VL0 NAI 5.47945
199 2XVF FAD 5.58767
200 1GZ6 NAI 5.64263
201 2EV9 NAP 5.70342
202 2EV9 SKM 5.70342
203 2XVE FAD 5.78035
204 2D3S TNR 5.78512
205 3CIF NAD 5.84958
206 3CIF G3H 5.84958
207 2HIM ASN 5.86592
208 4YDU ADP 5.90717
209 5EOW FAD 5.92593
210 5EVY FAD 5.93607
211 1A78 TDG 5.97015
212 5N0J FAD 5.97302
213 1N2X SAM 5.98007
214 4ZFL 4NK 5.98291
215 5VN0 FAD 5.98456
216 5VN0 NAI 5.98456
217 1GR0 NAD 5.99455
218 3FZG SAM 6
219 1LDN NAD 6.01266
220 6FHO FAD 6.01504
221 1PS9 FAD 6.03448
222 1PJS NAD 6.03448
223 1H82 FAD 6.03448
224 4USQ FAD 6.03448
225 1H82 GZZ 6.03448
226 3G5S FAD 6.03448
227 2E5V FAD 6.03448
228 4IV9 FAD 6.03448
229 5HXI FAD 6.03448
230 4K5S FAD 6.03448
231 4K5S PM0 6.03448
232 4D79 ATP 6.03448
233 4TXI FAD 6.03448
234 5HXI 5HN 6.03448
235 3GMB FAD 6.03448
236 5MQ6 NDP 6.03448
237 1I9G SAM 6.03448
238 5N6C NAD 6.03448
239 4KIB SAH 6.03448
240 2PV7 NAD 6.03448
241 1EBF NAD 6.03448
242 2JHP SAH 6.03448
243 2YX1 SFG 6.03448
244 5J6Y BGC 6.03448
245 5J6Y GLC 6.03448
246 1R18 SAH 6.03448
247 1PS9 NAP 6.03448
248 1L1E SAH 6.03448
249 2PXX SAH 6.03448
250 4CQM NAP 6.03448
251 1KGZ PRP 6.03448
252 1B74 DGN 6.03448
253 6BII NAP 6.03448
254 3T4L ZEA 6.03448
255 4DZ1 DAL 6.03448
256 1PNO NAP 6.03448
257 1UP7 NAD 6.03448
258 3A16 PXO 6.03448
259 1GPM CIT 6.03448
260 2EB5 OXL 6.03448
261 3AFH GSU 6.03448
262 1P0F NAP 6.03448
263 3QH2 3NM 6.03448
264 6DNT NAD 6.03448
265 5E72 SAM 6.03448
266 3C7A NAD 6.03448
267 6F90 MVL 6.03448
268 1P31 EPU 6.03448
269 5UR0 NAD 6.03448
270 4U60 SIA GAL NGA 6.03448
271 1HYH NAD 6.03448
272 5YU3 NAD 6.03448
273 5YU3 PRO 6.03448
274 1UWK NAD 6.03448
275 1UWK URO 6.03448
276 1ORR NAD 6.05187
277 1XXR MAN 6.21118
278 1X14 NAD 6.23441
279 3E1T FAD 6.25
280 5OFW 9TW 6.27803
281 3BAZ NAP 6.30631
282 4TM3 FAD 6.35838
283 1H5R THM 6.35838
284 2PZE ATP 6.35838
285 5F8F SFG 6.36605
286 2G5C NAD 6.40569
287 5Z75 NAD 6.42202
288 3H8V ATP 6.50685
289 4XDY NAI 6.50888
290 5TUF TDC 6.55106
291 5TUF FAD 6.55106
292 5TUK FAD 6.55106
293 2HYQ MAN MAN 6.55738
294 2NU5 NAG 6.55738
295 3G5K BB2 6.55738
296 5ZW3 SAH 6.66667
297 1RDS GPC 6.66667
298 4XDZ NDP 6.70554
299 5OJL TXP 6.71141
300 3B20 NAD 6.78466
301 3B1J NAD 6.78466
302 1XCL SAH 6.80851
303 2AG8 NAP 6.84411
304 5GT9 NAP 6.84411
305 5XVH NAP 6.86275
306 4NTC FAD 6.89655
307 3T31 FAD 6.89655
308 3T31 DCQ 6.89655
309 1QO8 FAD 6.89655
310 2YG3 FAD 6.89655
311 3AYI FAD 6.89655
312 3AYI HCI 6.89655
313 2WET FAD 6.89655
314 6ER9 FAD 6.89655
315 6ER9 NAP 6.89655
316 2RGJ FAD 6.89655
317 5DNK SAH 6.89655
318 3GF4 UPG 6.89655
319 2RGO FAD 6.89655
320 3IHG FAD 6.89655
321 3GF4 FAD 6.89655
322 2HJR APR 6.89655
323 1LTH NAD 6.89655
324 5JE8 NAD 6.89655
325 3SSO SAH 6.89655
326 5FA5 MTA 6.89655
327 4RSL FAD 6.89655
328 3ULK NDP 6.89655
329 5ERG SAM 6.89655
330 5ZI9 FLC 6.89655
331 3VSE SAH 6.89655
332 4POO SAM 6.89655
333 5D4V SAH 6.89655
334 2O07 MTA 6.89655
335 1GQ2 NAP 6.89655
336 1J5P NAD 6.89655
337 4YMH SAH 6.89655
338 2XWL CTP 6.89655
339 3A06 NDP 6.89655
340 4DSG FAD 6.89655
341 4DSG UDP 6.89655
342 1WHT BZS 6.89655
343 5WP4 SAH 6.89655
344 4KRI SAH 6.89655
345 1V8B NAD 6.89655
346 2O07 SPD 6.89655
347 1EQ2 NAP 6.89655
348 3I7S PYR 6.89655
349 5LOG SAH 6.89655
350 1C3V NDP 6.89655
351 4EUE NAI 6.89655
352 2BZG SAH 6.89655
353 1EZ4 NAD 6.89655
354 2X6T NAP 6.89655
355 3LU1 NAD 6.89655
356 2V6G NAP 6.89655
357 4HY1 19X 6.89655
358 6C8R SAH 6.89655
359 1F3L SAH 6.89655
360 1CF2 NAP 6.89655
361 4F2Q QUS 6.89655
362 1PZG A3D 6.89655
363 4NVP 7CH 6.89655
364 1Z82 NDP 6.89655
365 2DBZ NAP 6.89655
366 2HK9 ATR 6.90909
367 2HK9 NAP 6.90909
368 2OG2 MLI 6.93642
369 3B9Q MLI 6.93642
370 4RDH AMP 6.94444
371 4RDI ATP 6.94444
372 2XVM SAH 7.03518
373 3MB5 SAM 7.05882
374 4OM8 NAD 7.11974
375 4YCA NDP 7.14286
376 3HAD NAD 7.14286
377 2UZ1 TPP 7.28242
378 1KPG SAH 7.31707
379 1KPH SAH 7.31707
380 1NAA ABL 7.32177
381 1NAA 6FA 7.32177
382 1X87 NAD 7.32177
383 3WV8 ATP 7.33945
384 5N18 8HZ 7.33945
385 3C1O NAP 7.47664
386 2RNF UM3 7.5
387 5JDI 6JO 7.63889
388 5AJU RP5 7.66423
389 1LVW TYD 7.70713
390 2UYP PPI 7.75194
391 4FWE FAD 7.75862
392 4OPC PGT 7.75862
393 4OPC FDA 7.75862
394 4GUS FAD 7.75862
395 4GUT FAD 7.75862
396 4HSU FAD 7.75862
397 4YNU LGC 7.75862
398 4YNU FAD 7.75862
399 3UOY FAD 7.75862
400 3UOY NAP 7.75862
401 4B63 NAP 7.75862
402 4B63 FAD 7.75862
403 4B63 ORN 7.75862
404 4MIG G3F 7.75862
405 4AP3 FAD 7.75862
406 4AP3 NAP 7.75862
407 1RP0 AHZ 7.75862
408 5EZ7 FAD 7.75862
409 5HSA FAS 7.75862
410 2Y6Q I7T 7.75862
411 2Y6Q FAD 7.75862
412 4C4A SAH 7.75862
413 3FUU ADN 7.75862
414 5LD5 NAD 7.75862
415 1GUZ NAD 7.75862
416 5WP5 SAH 7.75862
417 1LDM NAD 7.75862
418 3MAG SAH 7.75862
419 2RI1 GLP 7.75862
420 5X20 NAD 7.75862
421 3DMH SAM 7.75862
422 2NU8 COA 7.75862
423 3DUW SAH 7.75862
424 3MCT SAH 7.75862
425 4E5N NAD 7.75862
426 1BXK NAD 7.75862
427 1NYT NAP 7.75862
428 2EJU SAH 7.75862
429 6EL3 NAP 7.75862
430 2HNK SAH 7.75862
431 1HSL HIS 7.75862
432 3DMH GMP 7.75862
433 3R51 MMA 7.75862
434 3TY3 GGG 7.75862
435 3KAL HGS 7.75862
436 2YIV YIV 7.75862
437 3GCZ SAM 7.75862
438 4W6Z 8ID 7.78098
439 4PLG NAI 7.78443
440 4PLG OXM 7.78443
441 4DR9 BB2 7.8125
442 2C7G FAD 7.89474
443 2C7G ODP 7.89474
444 3S5W NAP 7.89981
445 4J36 FAD 7.89981
446 4J36 1HR 7.89981
447 3S5W FAD 7.89981
448 4NEC SAH 7.95455
449 5N5D SAM 7.9646
450 5AOV NAP 8.03571
451 1P1C SAH 8.0402
452 2DT5 NAD 8.05687
453 4EIP FAD 8.09249
454 4EIP K2C 8.09249
455 3WMX NAD 8.09249
456 5X62 SAH 8.12808
457 1Y63 ADP 8.15217
458 5X68 FAD 8.18414
459 4EMI NAD 8.29268
460 4EMI FAD 8.29268
461 4GLL NAD 8.30861
462 6FDF SAH 8.38323
463 5AYV NAP 8.41424
464 5AYV KPL 8.41424
465 3FG2 FAD 8.41584
466 3LL5 IP8 8.43373
467 5NC1 NAG 8.43882
468 1G60 SAM 8.46154
469 3BGD SAH 8.46154
470 2YLN CYS 8.48057
471 3T7S SAM 8.58209
472 2BRY FAD 8.62069
473 1GTE FAD 8.62069
474 1E1M NAP 8.62069
475 1E1M FAD 8.62069
476 1E6E FAD 8.62069
477 2VVM FAD 8.62069
478 3X0V FAD 8.62069
479 2VVL FAD 8.62069
480 5FJN BE2 8.62069
481 5FJN FAD 8.62069
482 3QJ4 FAD 8.62069
483 1P77 ATR 8.62069
484 1MUU NAD 8.62069
485 1WDK NAD 8.62069
486 3L9W GSH 8.62069
487 2VDV SAM 8.62069
488 5BW4 SAM 8.62069
489 2AOT SAH 8.62069
490 1O6Z NAD 8.62069
491 1YXM ADE 8.62069
492 1EJ0 SAM 8.62069
493 5HS2 CTP 8.62069
494 1DL5 SAH 8.62069
495 3WBF NAP 8.62069
496 1D1T NAD 8.62069
497 3OBT SLB 8.62069
498 3TLJ SAH 8.62069
499 3WBF API 8.62069
500 1GY8 NAD 8.62069
501 3L9W AMP 8.62069
502 5JJR SAH 8.62069
503 4A59 AMP 8.62069
504 5ZZ6 ADP 8.65385
505 5ZZ6 NAD 8.65385
506 3DAG FEG 8.65922
507 5BSH PRO 8.66426
508 4X9M FAD 8.67052
509 5HJM MTA 8.67052
510 1LUA NAP 8.7108
511 2BES RES 8.72093
512 5L95 AMP 8.75
513 3ORF NAD 8.76494
514 4YMZ 13P 8.76494
515 3OFK SAH 8.7963
516 1O5I NAD 8.83534
517 4JNA FAD 8.8632
518 4Y9D NAI 8.8632
519 5DN9 NAD 8.8632
520 3GXZ BMA MAN MAN MAN 8.91089
521 2VOH CIT 8.9172
522 1UGY GLA GLC 9.02256
523 1YY5 FAD 9.05588
524 3UWB BB2 9.09091
525 6ECU SAH 9.17722
526 2FK8 SAM 9.24856
527 4ZRN NAD 9.29487
528 5TQZ GLC 9.33333
529 4EMJ FAD 9.34579
530 4Z24 FAD 9.35583
531 5K0A FAD 9.39394
532 4AT0 FAD 9.41177
533 4CT7 TRP 9.46502
534 1KYQ NAD 9.48276
535 5BRT FAD 9.48276
536 5BRT CH9 9.48276
537 1REO FAD 9.48276
538 2JB2 PHE 9.48276
539 2JB2 FAD 9.48276
540 3GDN HBX 9.48276
541 3GDN FAD 9.48276
542 5EB4 FAD 9.48276
543 3HDY FDA 9.48276
544 3HDY GDU 9.48276
545 5I39 FAD 9.48276
546 3HDY FAD 9.48276
547 5J7X FAD 9.48276
548 3X0D SAH 9.48276
549 1OMO NAD 9.48276
550 6C4N NAP 9.48276
551 1HDG NAD 9.48276
552 1ZQ9 SAM 9.48276
553 1ELI PYC 9.48276
554 2AWN ADP 9.48276
555 1HKU NAD 9.48276
556 3L4S NAD 9.48276
557 3L4S 3PG 9.48276
558 4PLT OXM 9.48276
559 4PLT NAI 9.48276
560 5KOK SAH 9.48276
561 1WG8 SAM 9.48276
562 4ZEV M6P 9.48276
563 2QQF A1R 9.48276
564 3C6K SPD 9.48276
565 4YUW S4M 9.48276
566 4YUW 4JU 9.48276
567 3H5N ATP 9.48276
568 1Z45 NAD 9.48276
569 6ECT SAM 9.48276
570 4RF7 ARG 9.48276
571 6D6Y SAH 9.48276
572 1US5 GLU 9.48276
573 3L6C MLI 9.48276
574 1K3T BRZ 9.48276
575 1Q0S SAH 9.48276
576 1Y4Z PCI 9.48276
577 1LK7 DER 9.48276
578 3C6K MTA 9.48276
579 1OBB NAD 9.48276
580 6ECW SAH 9.48276
581 3RFV 15L 9.48276
582 4OKE AMP 9.52381
583 5E1M SAH 9.54357
584 5UAV TFB 9.62733
585 5UAV NDP 9.62733
586 2HXW FLC 9.70464
587 3LST SAH 9.77011
588 5U19 827 10.0193
589 5U19 SAH 10.0193
590 3K56 IS3 10.1504
591 4B4U NAP 10.231
592 5W7K SAH 10.2564
593 4YKG FAD 10.3448
594 4YKG NAD 10.3448
595 3NT6 FAD 10.3448
596 3NTA FAD 10.3448
597 5BVA FAD 10.3448
598 5JWC FAD 10.3448
599 3K7M FAD 10.3448
600 5YB7 FAD 10.3448
601 5YB7 ORN 10.3448
602 1GAD NAD 10.3448
603 1NPD NAD 10.3448
604 1NVM NAD 10.3448
605 4D3F NAP 10.3448
606 3JWH SAH 10.3448
607 5E9W SAH 10.3448
608 2XYQ SAH 10.3448
609 6FA4 D1W 10.3448
610 2F5X ASP 10.3448
611 5A1T NAI 10.3448
612 2JK0 ASP 10.3448
613 3V1U NAD 10.3448
614 5O98 NAP 10.3448
615 5A1T OXM 10.3448
616 1LC3 NAD 10.3448
617 1UXG FUM 10.356
618 1UXG NAD 10.356
619 3TKA SAM 10.3746
620 1FWV SGA MAG FUC 10.4478
621 6E8I PTR 10.6509
622 1IM8 SAI 10.6557
623 1A5Z NAD 10.6583
624 1SOW NAD 10.6707
625 5GZ6 NDP 10.7362
626 5GZ6 7C3 10.7362
627 5U5N NAD 10.7527
628 5O4J PJL 10.9489
629 5O4J 9KH 10.9489
630 5O4J SAH 10.9489
631 6A3J NAI 10.9827
632 6BVE PGA 11.0204
633 2NXE SAM 11.0236
634 2VT3 ATP 11.1628
635 4C3Y FAD 11.1753
636 4C3Y ANB 11.1753
637 2GMH FAD 11.2069
638 5MBX SP5 11.2069
639 5MBX FAD 11.2069
640 2QA1 FAD 11.2069
641 2DKH FAD 11.2069
642 2VYN NAD 11.2069
643 2DKH 3HB 11.2069
644 6AIN FAD 11.2069
645 2OOR NAD 11.2069
646 3AXB PRO 11.2069
647 3AXB FAD 11.2069
648 1F8G NAD 11.2069
649 3VPH NAD 11.2069
650 3A27 SAM 11.2069
651 2PWY SAH 11.2069
652 3VPH OXM 11.2069
653 5YF1 SFG 11.2069
654 1L7E NAI 11.2069
655 1QAN SAH 11.2069
656 3CBG SAH 11.2069
657 4LWP SAH 11.2069
658 1TPY SAH 11.2069
659 1NM5 NAD 11.2069
660 2VHW NAI 11.2069
661 4XG0 CIT 11.2069
662 1L3I SAH 11.2069
663 5NM7 GLY 11.2069
664 1XDS SAM 11.2069
665 1HE1 AF3 11.2069
666 5FUB SAH 11.2069
667 1XTP SAI 11.2069
668 4XFR CIT 11.2069
669 3TD3 GLY 11.2069
670 4NAE 1GP 11.2069
671 2OOR TXP 11.2069
672 1G55 SAH 11.2069
673 4JJF FE9 11.2069
674 5AOA PPI 11.2069
675 2OEM 1AE 11.2069
676 2X77 GDP 11.2069
677 5YRF GLC GLC 11.2676
678 2CDU ADP 11.2832
679 2CDU FAD 11.2832
680 5AHO TLA 11.3095
681 3A3B RBF 11.5789
682 1GV0 NAD 11.6129
683 1DLJ NAI 11.6915
684 1DLJ UGA 11.6915
685 3WLE NAD 11.7302
686 2FWP ICR 12.0219
687 2ZXI FAD 12.069
688 6GNA FAD 12.069
689 1GPE FAD 12.069
690 3NKS FAD 12.069
691 2RGH FAD 12.069
692 5G3U FDA 12.069
693 1C0I FAD 12.069
694 1C0I BE2 12.069
695 5G3U ITW 12.069
696 1I36 NAP 12.069
697 2DFV NAD 12.069
698 5ZBC FAD 12.069
699 1VI2 NAD 12.069
700 4DMG SAM 12.069
701 5OCM NAP 12.069
702 5Z21 NAI 12.069
703 4TSK NDP 12.069
704 4YT4 FE9 12.069
705 4N49 SAM 12.069
706 6AM8 TRP 12.069
707 5M67 3D1 12.069
708 5M67 NAD 12.069
709 5M67 ADE 12.069
710 3AD8 NAD 12.1212
711 3AD8 PYC 12.1212
712 3AD8 FAD 12.1212
713 3KB6 NAD 12.8743
714 1BW9 NAD 12.9213
715 1BXG NAD 12.9213
716 1BW9 PPY 12.9213
717 6GNC FAD 12.931
718 2Z3Y F2N 12.931
719 5UAO FAD 12.931
720 1Y8Q ATP 12.931
721 4MO2 FAD 12.931
722 4MO2 FDA 12.931
723 1J49 NAD 12.931
724 2PT9 S4M 12.931
725 5CAE COA 12.931
726 3OA2 NAD 12.931
727 3LCC SAH 12.931
728 4XGX ADP 12.931
729 4U00 ADP 12.931
730 4AZW SAM 12.931
731 2PT9 2MH 12.931
732 5N2I NAP 12.931
733 4XQC 13D 12.931
734 4XQC NAD 12.931
735 1C1X NAD 12.9577
736 1C1X HFA 12.9577
737 2GAG NAD 13.1313
738 2GAG FAD 13.1313
739 2GAG FOA 13.1313
740 1OUW MLT 13.1579
741 5C79 PBU 13.3333
742 4XZ3 COA 13.4783
743 4LFL TG6 13.5802
744 1JAY NAP 13.6792
745 1D4D FAD 13.7931
746 4CNK FAD 13.7931
747 6AA8 NAD 13.7931
748 4HA6 FAD 13.7931
749 3ZNN 4WL 13.7931
750 3ZNN FAD 13.7931
751 3H9E NAD 13.7931
752 3ABI NAD 13.7931
753 4KRG SAH 13.7931
754 2ZIF SAM 13.7931
755 2P3V SRT 13.7931
756 5BJX NAD 13.7931
757 1T9D P22 13.7931
758 5BJX UDP 13.7931
759 4FZV SAM 13.7931
760 1KAE NAD 13.7931
761 1R6B ADP 13.7931
762 1FL2 FAD 13.871
763 1YKJ PHB 13.9594
764 1YKJ FAD 13.9594
765 1E3W NAD 14.1762
766 2YVF FAD 14.2157
767 2YVF NAD 14.2157
768 2YVJ FAD 14.2157
769 2YVJ NAI 14.2157
770 5YEC ATP 14.2857
771 1XG5 NAP 14.3369
772 5JCM ISD 14.4124
773 5JCM NAD 14.4124
774 5JCM FAD 14.4124
775 4YAC NAI 14.4781
776 1CER NAD 14.5015
777 6F7L FAD 14.6552
778 1COY AND 14.6552
779 1COY FAD 14.6552
780 2A92 NAI 14.6552
781 1YS4 NAP 14.6552
782 1VL1 CIT 14.6552
783 5Y8L NAD 14.6552
784 5Y8L HUI 14.6552
785 4D7E FAD 14.6552
786 4RQU NAD 14.6552
787 6CEP NAD 14.6552
788 2PK3 A2R 14.6552
789 6CEP OXM 14.6552
790 1LLU NAD 14.6552
791 4BVA NDP 14.6552
792 2I7C AAT 14.6552
793 6F5Z SAH 14.7541
794 2Q1S NAI 14.8362
795 3GGO NAI 14.8362
796 3GGO ENO 14.8362
797 1SC6 NAD 14.8515
798 1Q1R FAD 15.0812
799 1JNR FAD 15.5172
800 3OZ2 FAD 15.5172
801 1PN0 FAD 15.5172
802 1PN0 IPH 15.5172
803 2AQJ FAD 15.5172
804 2AQJ TRP 15.5172
805 3QVP FAD 15.5172
806 4MOP 2H5 15.5172
807 4F8L AES 15.5172
808 1DIG NAP 15.5172
809 3TN7 NJP 15.5172
810 1CDO NAD 15.5172
811 4QTU SAM 15.5556
812 6G3R ADP 15.7895
813 3QV1 NAD 15.8537
814 1UKG MMA 15.873
815 1Q8Q MAN MMA 15.873
816 1Q8S MAN MMA 15.873
817 2PHX MAN MAN 15.873
818 2GND MAN 15.873
819 1Q8V MAN MAN 15.873
820 1Q8P MAN MMA 15.873
821 2GND MAN MMA 15.873
822 1Q8O MAN MMA 15.873
823 2PHF MAN MAN BMA MAN 15.873
824 2PHR MAN MAN BMA MAN 15.873
825 2GNB MAN 15.873
826 2GN3 MAN 15.873
827 5E8J SAH 15.9091
828 5A04 BGC 15.9292
829 5A04 NDP 15.9292
830 4YSX FAD 15.9574
831 4USI AKG 16.2338
832 4KVL PLM 16.3793
833 1QMG APX 16.3793
834 1ZEM NAD 16.3793
835 3G2O SAM 16.3793
836 2IDV M7G 16.3793
837 3TTY GLA 16.3793
838 3OJO NAD 16.3793
839 4OOE NDP 16.3793
840 1ZBQ NAD 16.3793
841 2DC1 NAD 16.5254
842 1JQ3 AAT 16.5541
843 4II2 ATP 16.8675
844 1V6A TRE 16.8675
845 3EGI ADP 17.2414
846 1O0S NAI 17.2414
847 1LJ8 NAD 17.2414
848 1M2W NAD 17.2414
849 5T96 79J 17.2414
850 1M2W MTL 17.2414
851 3GDH SAH 17.2414
852 4IWN GEK 17.2414
853 1Y1P NMN AMP PO4 17.2414
854 3LXD FAD 17.3494
855 5H81 NAP 17.4807
856 9LDT NAD 17.7711
857 9LDB NAD 17.7711
858 4ZVV NAD 17.7711
859 4ZVV GN0 17.7711
860 3AB1 FAD 18.1034
861 3Q9T FAY 18.1034
862 2Q1W NAD 18.1034
863 1D4O NAP 18.1034
864 1DJL NAP 18.1034
865 5I34 GDP 18.1034
866 2QV7 ADP 18.1034
867 5X9D 80F 18.1034
868 5BXV MGP 18.1818
869 5EIN NAP 18.5185
870 2NPX NAD 18.5682
871 2NPX FAD 18.5682
872 5NA1 FAD 18.6275
873 1O94 ADP 18.8825
874 1DJN ADP 18.8825
875 1LSS NAD 18.9655
876 4RPL 3UC 18.9655
877 4RPL FAD 18.9655
878 5TCI MLI 18.9655
879 1MZV AMP 18.9655
880 3NTD FAD 19.0751
881 3CGB FAD 19.1667
882 6H3O FAD 19.8276
883 1NV8 MEQ 19.8276
884 1NV8 SAM 19.8276
885 2BNE U5P 19.8276
886 3B1F NAD 20.6897
887 6C4T NA7 20.6897
888 3FPF MTA 20.6897
889 3FPF TNA 20.6897
890 4WOV 3SM 20.6897
891 1VDC FAD 21.021
892 5KMS FAD 21.2346
893 5KMS NAD 21.2346
894 4DCM SAM 21.5517
895 2W58 ADP 21.5517
896 5NII FAD 21.6828
897 3K5I AIR 22.4138
898 1GEE NAD 22.4138
899 4NTD FAD 22.9412
900 6C4M NAP 23.2759
901 3KLJ FAD 23.6364
902 5KOX FAD 24.1379
903 5KOX RFP 24.1379
904 1HDR NAD 24.1379
905 1RLJ FMN 24.1379
906 3CGD FAD 24.2775
907 3CGD COA 24.2775
908 3CGD NAD 24.2775
909 1YQZ FAD 24.4292
910 3W9K MYR 24.4604
911 5TWB FAD 25
912 2YYY NAP 25
913 1VM6 NAD 25
914 6GAS FAD 25.3776
915 3GRU AMP 25.8621
916 6GAR FAD 26.2042
917 3LZW NAP 26.2048
918 3LZW FAD 26.2048
919 4YRY NAD 26.7094
920 4YRY FAD 26.7094
921 5ODQ FAD 26.7241
922 2CUL FAD 27.1552
923 4GQB 0XU 27.2727
924 5J60 FAD 27.5
925 3ICS FAD 27.9383
926 3ICR FAD 27.9383
927 3ICT FAD 27.9383
928 3ICT ADP 27.9383
929 3ICS ADP 27.9383
930 3F8D FAD 28.1734
931 5JCA NDP 28.3237
932 5JCA FAD 28.3237
933 4M38 SAH 28.5714
934 1LOB MMA 28.8462
935 1TDF NAP 30.0633
936 1TDF FAD 30.0633
937 3CTY FAD 30.4075
938 1XHC FAD 32.1526
939 2I6U NVA 32.7586
940 3TA2 AKG 35.5932
941 5C2N NAG 37.5
942 1ZK7 FAD 39.1863
943 1LVL FAD 41.7031
944 1LVL NAD 41.7031
945 4JDR FAD 41.8112
946 1MO9 KPC 42.3892
947 1MO9 FAD 42.3892
948 1V59 FAD 43.1599
949 1V59 NAD 43.1599
950 3LAD FAD 43.5453
951 5U8U FAD 44.316
952 2A8X FAD 45.4741
953 4M52 FAD 45.7082
954 4M52 M52 45.7082
955 2F5Z FAD 46.6245
956 5J5Z FAD 46.6281
957 3RNM FAD 46.6281
958 1FEC FAD 47.2062
959 1BZL GCG 48.5597
960 1BZL FAD 48.5597
961 2WPF FAD 49.3256
962 2WPF WPF 49.3256
Pocket No.: 2; Query (leader) PDB : 3QFA; Ligand: FAD; Similar sites found with APoc: 71
This union binding pocket(no: 2) in the query (biounit: 3qfa.bio1) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 3HIY UTP 2.58621
2 3HJ1 UTP 2.58621
3 5AHW CMP 3.40136
4 1RRC ADP 3.44828
5 1KYZ SAH 3.44828
6 4CL6 7SB 3.50877
7 3GWZ SAH 5.14905
8 3H2B SAH 5.17241
9 5GWE GWM 5.17241
10 1WVG APR 5.17241
11 1B8U NAD 5.17241
12 3QVL 5HY 5.39499
13 1VRP ADP 5.51181
14 1GZW GAL BGC 6.03448
15 1W6O LAT 6.03448
16 1W6P NDG GAL 6.03448
17 4CCK OGA 6.03448
18 3MQ2 SAH 6.03448
19 1M2K APR 6.03448
20 1SO2 666 6.03448
21 5N53 8NB 6.15385
22 2NUO BGC 6.55738
23 3SAO DBH 6.89655
24 5LX9 OLA 6.89655
25 3HVJ 705 6.89655
26 4DE3 DN8 7.22433
27 5HP8 PYR 7.25806
28 3SHR CMP 7.35786
29 1U1W 3HA 7.38255
30 2D0O ADP 7.75862
31 4MCC 21X 7.75862
32 1TL2 NDG 8.62069
33 3C3Y SAH 8.86076
34 1JJ7 ADP 9.23077
35 2XYA 7L4 9.48276
36 3P2E SAH 9.48276
37 5K4W NAI 10.3448
38 4JZ8 CIT 11.2069
39 3LKZ SFG 11.2069
40 3AY6 NAI 11.2069
41 5MGZ SAH 11.2069
42 5EYY MDM 11.4286
43 3A3B FMN 11.5789
44 5X2N ALA 12.069
45 3QOX SAH 12.069
46 3GEG NAD 12.069
47 1QZZ SAM 12.069
48 1V1A ADP 12.931
49 3AB4 LYS 14.6067
50 3EFS BTN 15.5172
51 2PHU MAN MAN 15.873
52 2PHW MAN MAN 15.873
53 2PHR MAN MAN 15.873
54 2PHF MAN MAN 15.873
55 2PHT MAN MAN MAN 15.873
56 2AUY NAG MAN MMA 15.873
57 2AR6 NAG MAN 15.873
58 2GN3 MMA 15.873
59 2PHT MAN MAN MAN BMA MAN 15.873
60 2PHU MAN MAN MAN BMA MAN 15.873
61 2PHW MAN MAN MAN BMA MAN MAN MAN 15.873
62 2AR6 NAG MAN MAN MAN NAG 15.873
63 2GMP NAG MAN 15.873
64 3BF1 PAU 16.3793
65 1FIW PBZ 17.2414
66 2ZFU SAH 19.8276
67 2CUN 3PG 19.8276
68 6C7Y ADP 20.6294
69 1O5E 132 21.9298
70 1N13 AG2 23.0769
71 2Y7I ARG 24.0175
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