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Receptor
PDB id Resolution Class Description Source Keywords
3QF7 1.9 Å NON-ENZYME: BINDING THE MRE11:RAD50 COMPLEX FORMS AN ATP DEPENDENT MOLECULAR CLA DOUBLE-STRAND BREAK REPAIR THERMOTOGA MARITIMA ABC-ATPASE ATPASE MRE11 HYDROLASE
Ref.: THE MRE11:RAD50 STRUCTURE SHOWS AN ATP-DEPENDENT MO CLAMP IN DNA DOUBLE-STRAND BREAK REPAIR. CELL(CAMBRIDGE,MASS.) V. 145 54 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:853;
B:853;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:854;
B:854;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3QF7 1.9 Å NON-ENZYME: BINDING THE MRE11:RAD50 COMPLEX FORMS AN ATP DEPENDENT MOLECULAR CLA DOUBLE-STRAND BREAK REPAIR THERMOTOGA MARITIMA ABC-ATPASE ATPASE MRE11 HYDROLASE
Ref.: THE MRE11:RAD50 STRUCTURE SHOWS AN ATP-DEPENDENT MO CLAMP IN DNA DOUBLE-STRAND BREAK REPAIR. CELL(CAMBRIDGE,MASS.) V. 145 54 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 3QF7 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 3QF7 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 3QF7 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3QF7; Ligand: ANP; Similar sites found with APoc: 668
This union binding pocket(no: 1) in the query (biounit: 3qf7.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 1GXU 2HP None
2 2ZFZ ARG None
3 5C2N NAG None
4 2BO4 FLC 1.36986
5 1NXJ TLA 1.63934
6 2JLR ANP 1.64384
7 1GOJ ADP 1.69014
8 5GVR LMR 1.7094
9 2XTN GTP 1.7094
10 3DC4 ADP 1.74419
11 2DPY ADP 1.91781
12 3G6K FAD 1.94805
13 3G6K POP 1.94805
14 2HCJ GDP 2.08955
15 5TVI O8N 2.17391
16 3COB ADP 2.19178
17 4NCN GTP 2.19178
18 2CKM AA7 2.19178
19 5XWV NDP 2.19178
20 5XWV 8H6 2.19178
21 4TMZ GSP 2.31884
22 2J0W ASP 2.46575
23 2WOJ ADP ALF 2.54237
24 3ZS9 ADP ALF 2.54237
25 4UTG ANP 2.60116
26 3HP8 SUC 2.72727
27 2YVF NAD 2.73973
28 2YVF FAD 2.73973
29 4E03 ADP 2.91262
30 2WHX ADP 3.0137
31 1OS1 PYR 3.0137
32 1OS1 ATP 3.0137
33 4HXY NDP 3.0137
34 5M04 GDP 3.05556
35 3EWA ANP 3.10559
36 1DAK DPU 3.125
37 1DAK ADP 3.125
38 3DKP ADP 3.26531
39 4BQS ADP 3.40909
40 4BQS K2Q 3.40909
41 2ORV 4TA 3.4188
42 4PX9 ADP 3.42466
43 6CI9 NAP 3.4749
44 4HE2 AMP 3.5503
45 3BER AMP 3.61446
46 3GJ7 GDP 3.61991
47 3GJ4 GDP 3.61991
48 3GJ5 GDP 3.61991
49 3GJ0 GDP 3.61991
50 3GJ3 GDP 3.61991
51 3GJ8 GDP 3.61991
52 3MD0 GDP 3.66197
53 3CH5 GDP 3.7037
54 1HTW ADP 3.79747
55 2ZEJ GDP 3.80435
56 2VOH CIT 3.82166
57 1X1R GDP 3.93258
58 2Y65 ADP 4
59 2GDJ ANP 4
60 1D2E GDP 4
61 3U6B GDP 4.10959
62 2BVN GNP 4.10959
63 1SQ5 ADP 4.10959
64 6FAA ADP 4.10959
65 1D8T GDP 4.10959
66 4G5G GDP 4.10959
67 5JBQ GDP 4.10959
68 3U6K GDP 4.10959
69 1G16 GDP 4.11765
70 1YVD GNP 4.14201
71 3KC1 2T6 4.1543
72 1UJ2 ADP 4.36508
73 1UJ2 C5P 4.36508
74 5W76 GDP 4.38356
75 4R43 GDP 4.38356
76 1FP6 ADP 4.49827
77 3TK1 GDP 4.54545
78 2ZX2 RAM 4.61538
79 4C4P GNP 4.62428
80 4PC3 GDP 4.65753
81 1XX6 ADP 4.71204
82 2ZTS ADP 4.78088
83 2D7C GTP 4.79042
84 4HDO GNP 4.79042
85 3X1Z GNP 4.79042
86 3Q72 GNP 4.81928
87 3ZOK GLY 4.93151
88 1MR3 G3D 4.97238
89 2RCN GDP 5.02793
90 1Z0F GDP 5.02793
91 1XKV ATP 5.20548
92 2J5V PCA 5.20548
93 4QM7 GTP 5.26316
94 3FYH ADP 5.2795
95 1R2Q GNP 5.29412
96 2ZPT A3P 5.42373
97 5W7Q GDP 5.47945
98 4BAS GNP 5.52764
99 4RD0 GDP 5.75342
100 4D0G GTP 5.7971
101 1GWN GTP 5.85366
102 4NU0 AP5 6
103 4X8O AP5 6
104 5H7K GDP 6
105 1W4R TTP 6
106 1OIX GDP 6
107 1U8Z GDP 6
108 2A9K GDP 6
109 1OIV GDP 6
110 3FWY ADP 6
111 4OUE IPT 6
112 2IS6 ADP 6
113 1OYY AGS 6
114 3RK1 ATP 6
115 4R98 GNH 6
116 4GOX A3P 6
117 2NCD ADP 6.0274
118 6B4K ANP 6.0274
119 1GUA GNP 6.17284
120 2YOH WMJ 6.19048
121 4WOP CTP 6.22222
122 5XC5 GTP 6.25
123 4Z7X 3CX 6.30252
124 3W5J GDP 6.37255
125 3QBT GNP 6.42857
126 5EE5 GTP 6.43275
127 2B4B COA 6.43275
128 2B4D COA 6.43275
129 2BME GNP 6.45161
130 1M7B GTP 6.52174
131 3DEF GDP 6.57534
132 4H1V GNP 6.57534
133 1Z83 AP5 6.57534
134 3IUY AMP 6.57895
135 1KO8 6PG 6.85714
136 2GJ8 ALF GDP 6.97674
137 1UAD GNP 7.07071
138 2D2F ADP 7.2
139 4HUT ATP 7.32984
140 1S8F GDP 7.34463
141 5OEC GDP 7.65027
142 4CQM NAP 7.66284
143 1JJV ATP 7.67123
144 4KAX GTP 7.69231
145 2IL4 COA 7.76699
146 3QVV A3P 7.79661
147 5HV7 RBL 8
148 4WEI GLC GAL 8
149 5KSP GDP 8
150 4NE2 ADP 8
151 4NE2 SH2 8
152 4ZNL BEF ADP 8
153 4R2I ANP 8
154 5I0H ADP BEF 8
155 2QEN ADP 8
156 2Q2Y MKR 8
157 2Q2Y ADP 8
158 2ZPA ADP 8
159 4BFW ZVW 8
160 1Y63 ADP 8
161 1IHU ADP 8
162 1IHU AF3 8
163 3KJI ADP 8
164 2B8T THM 8
165 2Q8M AMP 8
166 3FKQ ATP 8
167 5KSZ GCP 8
168 4V03 ADP 8
169 4RZ3 ADP 8
170 2F9L GDP 8.0402
171 1G6H ADP 8.17121
172 1SVI GDP 8.20513
173 1VG8 GNP 8.21256
174 1Z08 GNP 8.23529
175 4P3Y GDP 8.24176
176 2ZR9 DTP 8.30946
177 3N5C GDP 8.64198
178 1YZN GNP 8.64865
179 1Z0K GTP 8.69565
180 3FIU POP 8.83534
181 4LJ9 ACP 8.84956
182 2EW1 GNP 8.95522
183 2OFW ADX 9.13461
184 1VG1 GDP 9.18919
185 2HV8 GTP 9.375
186 4FCW ADP 9.6463
187 4MKF AP5 9.67742
188 1KAO GDP 9.86301
189 2V2V V12 9.9631
190 2W58 ADP 10
191 6B8B ADP 10
192 5TSH ADP 10
193 5TSH ANP 10
194 1V8K ANP 10
195 4J0Q GDP 10
196 1R6B ADP 10
197 2EFE GNH 10
198 2QTV GNP 10
199 1P72 ADP 10
200 1G41 ADP 10
201 4V0K GDP 10
202 3WXM GTP 10
203 3VMF GTP 10
204 3P4X ADP 10
205 4YJ1 ADP 10
206 5J1J ANP 10
207 1M2O GNP 10
208 2OQ2 A3P 10
209 1BO4 COA 10.119
210 5OCG GNP 10.582
211 2PEZ GGZ 10.6145
212 2PEZ DAT 10.6145
213 1ZC3 GNP 10.6195
214 1FZQ GDP 11.0497
215 4YLG GDP 11.5607
216 1Z2A GDP 11.9048
217 1U0J ADP 11.985
218 1JI0 ATP 12
219 1KK1 GNP 12
220 5W75 GDP 12
221 4MKG AP5 12
222 3TBK ANP 12
223 5G3Y ADP 12
224 3PCR GTP 12
225 3B7G ANP 12
226 2C9O ADP 12
227 4YDS ATP 12
228 1YTM ATP 12
229 4M9Q GNP 12
230 1WDT GTP 12
231 5MVR ADP 12
232 2CDN ADP 12
233 1RRC ADP 12
234 2FNA ADP 12
235 4LX0 BEF GDP 12
236 2GKS ADP 12
237 2C77 GNP 12
238 1VKJ A3P 12
239 2C78 GNP 12
240 5W75 SUC 12
241 4NON GDP 12
242 1BG2 ADP 12
243 6C90 ADP 12
244 6H5E ANP 12
245 2WJG GDP 12
246 1ION ADP 12
247 6HKE LMR 12
248 4UXH T5A 12
249 3REF GDP 12
250 2WJH FLC 12
251 1YXM ADE 12
252 2ZE7 AMP 12
253 2ZE7 DST 12
254 6HKE MLT 12
255 2WJH GDP 12
256 1NST A3P 12
257 1G3Q ADP 12
258 3VX3 ADP 12
259 4LC1 GDP 12.1662
260 2C3H GLC GLC 12.2449
261 5FEU NAP 12.3288
262 2Y8E GNP 12.8492
263 3IO3 ADP 13.1507
264 1UPT GTP 13.3333
265 2FFQ GSP 13.4503
266 1NN5 2DT 13.4884
267 1NN5 ANP 13.4884
268 1YZQ GNP 13.5294
269 4XTR ATP 13.913
270 4XVU ATP 13.913
271 4XTR ADP 13.913
272 2D7D ADP 13.9726
273 4CVN ADP 14
274 1G6O ADP 14
275 1W5T ANP 14
276 3HU3 AGS 14
277 3E70 GDP 14
278 2VB6 ADP BEF 14
279 5TB5 GDP 14
280 1W7J ADP BEF 14
281 1YZG GDP 14
282 1E2K TMC 14
283 5M7P ADP 14
284 4PFO ADP 14
285 3GJX GTP 14
286 1VG0 GDP 14
287 5N69 ADP 14
288 1W5T ADP 14
289 5WC2 ADP 14
290 5MZN ADP 14
291 4OHY ANP 14
292 3EC1 GDP 14
293 2XAU ADP 14
294 1UKZ ADP 14
295 1VG9 GDP 14
296 5DI3 GNP 14
297 5VGR GDP 14
298 5TAR GDP 14
299 3DZD ADP 14
300 5GOE GDP 14
301 1DS6 GDP 14
302 2KIN ADP 14
303 1H65 GDP 14
304 5L3R GCP 14
305 4CS9 AMP 14
306 5EP2 AZU 14
307 3LN9 FLC 14
308 2X7I CIT 14
309 5LLB 6YZ 14
310 4AVB ACO 14
311 4LHW GNP 14
312 4KSY 1SY 14
313 2PZ8 APC 14
314 5E5U MLI 14
315 4QRH 0O2 14
316 2FAH GDP 14
317 5X40 ACP 14.3836
318 2CK3 ADP 14.5205
319 1W0J ADP BEF 14.5205
320 2V7Q ATP 14.5205
321 2CK3 ANP 14.5205
322 1W0J ADP 14.5205
323 2V7Q ADP 14.5205
324 3E5H GNP 14.6067
325 3MJH GTP 14.7059
326 1D5C GDP 14.8148
327 2CBZ ATP 15.1899
328 1Z0A GDP 15.5172
329 1O3Y GTP 15.6627
330 2J59 GTP 15.6627
331 1J2J GTP 15.6627
332 2A5J GDP 15.7068
333 1JJ7 ADP 15.7692
334 5KUT GDP 15.873
335 5UQW GDP 15.873
336 2XT3 ADP 16
337 1SKQ GDP 16
338 3FVQ ATP 16
339 5LTJ BEF 16
340 2IXE ATP 16
341 2QZ4 ADP 16
342 3AQ4 GDP 16
343 2W83 GTP 16
344 4ZI2 GNP 16
345 4Q1A 2XZ 16
346 4Q1A UDP 16
347 6AU6 GDP 16
348 5L3V GDP 16
349 3LRE ADP 16
350 5LTJ ADP 16
351 2OBM ADP 16
352 4OI4 ATP 16
353 5WDR GNP 16
354 4LYA ATP 16
355 3BOS CDP 16
356 2WKQ GTP 16
357 3R7F CP 16
358 4KBF AMP 16
359 5JCP GDP ALF 16
360 4XSH GSP 16
361 6BCA GSP 16
362 6BCB GSP 16
363 5HR5 ADP 16
364 1Z06 GNP 16
365 1KMQ GNP 16
366 1CXZ GSP 16
367 4XOI GTP 16
368 2WIC GNP 16
369 5HPY GDP 16
370 3FSY SCA 16
371 1OW3 GDP 16
372 3MBI HSX 16
373 1TX4 ALF GDP 16
374 2GK6 ADP 16
375 3Q9L ATP 16
376 4YRY FAD 16
377 2PL3 ADP 16
378 4TTQ ATP 16
379 5UIV ADP 16.2996
380 1S9D GDP 16.4634
381 1RE0 GDP 16.4634
382 1LVG ADP 16.6667
383 5XKT GNP 17
384 5FFF NAP 17.2603
385 5FFF 5XC 17.2603
386 2C5L GTP 17.341
387 6FA4 GNP 17.341
388 4K81 GTP 17.5439
389 5O2T GSP 17.7515
390 5E95 GDP 17.8571
391 1LFD GNP 17.9641
392 4WZ6 ATP 18
393 2CE7 ADP 18
394 1NJF AGS 18
395 2QQ0 ANP 18
396 2QQ0 ADP 18
397 2QQ0 TMP 18
398 5ZBR ANP 18
399 1NJF ADP 18
400 1RJ9 GCP 18
401 3WYF GTP 18
402 3M1I GTP 18
403 5UWT GNP 18
404 5UWJ GNP 18
405 5UWI GNP 18
406 1ZJ6 G3D 18
407 5DI9 GNP 18
408 5UWR GNP 18
409 5UWU GNP 18
410 5DIF GNP 18
411 5UWS GNP 18
412 5UWQ GNP 18
413 6CIT GNP 18
414 4HAT GNP 18
415 5DHF GNP 18
416 5UWP GNP 18
417 1TQ4 GDP 18
418 3NKV GNP 18
419 2VVG ADP 18
420 5H7J GCP 18
421 1NY5 ADP 18
422 5XDR ADP 18
423 6A20 ADP 18
424 1F9V ADP 18
425 1ZUI SKM 18
426 1VHT BA3 18
427 1TAD GDP 18
428 1TAD ALF 18
429 2IYL GDP 18
430 3CNL GNP 18
431 5O74 GDP 18
432 1WLJ U5P 18
433 1OE0 TTP 18
434 2QQ0 THM 18
435 1CLU DBG 18.0723
436 1WQ1 GDP 18.0723
437 5WLB GNP 18.0723
438 3KUD GDP 18.0723
439 1WQ1 AF3 18.0723
440 2UZI GTP 18.0723
441 5CK5 GDP 18.0822
442 2CHG ANP 18.1416
443 1Z0J GTP 18.6441
444 1L2T ATP 18.7234
445 3B5J 12D 18.93
446 3ZIA ADP 19.0476
447 3ZIA ATP 19.0476
448 3KTA AP5 19.6532
449 1M7G AV2 20
450 1I4D GDP 20
451 5LB3 ADP 20
452 4D0N GDP 20
453 5FHD ADP ALF 20
454 1LVK MNT BEF 20
455 3UIE ANP 20
456 1F6B GDP 20
457 2AWN ADP 20
458 5IRN ADP 20
459 1M7G ADP 20
460 1M7G ADX 20
461 5FTB ANP 20
462 5J1S ATP 20
463 1A4R GDP 20
464 2FSH ANP 20
465 1A4R GNH 20
466 1SVK ALF GDP 20
467 2XTZ GSP 20
468 1GRN GDP 20
469 2OZE AGS 20
470 1BH2 GSP 20
471 1GP2 GDP 20
472 4XGU ADP 20
473 1E96 GTP 20
474 1NF3 GNP 20
475 3T12 GDP ALF 20
476 1MH1 GNP 20
477 2I6U CP 20
478 4IEE AGS 20
479 2FJU GSP 20
480 2NGR GDP 20
481 1RYH GNP 20
482 3T1O GDP 20
483 2FH5 GTP 20
484 4DID GDP 20
485 1HE1 GDP 20
486 4Y4V DAL 20
487 4IOK ADP 20
488 1G4U GDP 20
489 4TMK T5A 20
490 2ZJ5 ADP 20
491 4IOK XPO 20
492 1XEX ATP 20.3488
493 2PZE ATP 20.524
494 2WMO GTP 20.5479
495 4YMU ATP 20.8333
496 3SBD GNP 20.8556
497 4U00 ADP 21.7213
498 4AG5 ADP 22
499 3RLF ANP 22
500 1SVM ATP 22
501 2A5F GTP 22
502 5VHC BEF ADP 22
503 4ZG4 VO4 ADP 22
504 3BC1 GNP 22
505 2RGX AP5 22
506 1KK8 BEF ADP 22
507 4KVG GTP 22
508 1B7T ADP 22
509 4WZA ACP 22
510 4WZA ADP 22
511 2ZFI ADP 22
512 3DDC GNP 22
513 3IIJ ADP 22
514 1GOT GDP 22
515 4YC7 GNP 22
516 3LXR GDP 22
517 4B47 GDP 22
518 4ITR GDP 22
519 1WF3 GNP 22
520 3QXC ATP 22
521 3WYG GTP 22.3684
522 2W2X GSP 22.5806
523 5BXQ GDP 24
524 1X6V ADP 24
525 1CR1 TTP 24
526 5IRR GSP 24
527 3SFV GDP 24
528 2BEK ATP 24
529 5HCN GCP 24
530 4QOS ADP 24
531 3BFV ADP 24
532 1XNG ATP 24
533 6CS8 F9Y 24
534 1KQP ADJ 24
535 2OM2 GDP 25
536 1R4A GNP 25.4902
537 4KFU ACP 26
538 1YQT ADP 26
539 5YV5 ADP 26
540 4JLV ADP 26
541 4HI0 GDP 26
542 2X77 GDP 26
543 3TKL GTP 26
544 3ZQ6 ADP ALF 26
545 1ZCB GDP 26
546 5JCZ GDP 26
547 4DKX GDP 26
548 3TMK T5A 26
549 1F5N GNP 26
550 1G7S GDP 26
551 1DAR GDP 26
552 1PUJ GNP 26
553 2JAQ DCP 26
554 1ZD9 GDP 26.0638
555 1B0U ATP 26.3359
556 4HDQ GNP 26.9231
557 5LEF GTP 27.2727
558 1OXV ANP 28
559 3B9Q MLI 28
560 5Y6N ADP 28
561 3RC3 ANP 28
562 1Z6T ADP 28
563 1WA5 GTP 28
564 1KSH GDP 28
565 4KVA GTP 28
566 3RAB GNP 28
567 1FQK GDP 28
568 4LPS GDP 28
569 4IDN GNP 28
570 2HF9 GSP 28
571 5UPK GNP 28
572 4JLS 3ZE 28
573 3AB4 THR 28
574 1FQJ GDP 28
575 2DTJ THR 28
576 5UWW GNP 28.5714
577 5YT0 GDP 28.5714
578 5IFS ADP 30
579 1R0X ATP 30
580 4IHQ ADP 30
581 1IBR GNP 30
582 4ZKD GDP 30
583 2BCG GDP 30
584 6D5J GNP 30
585 6D55 GNP 30
586 6D5L GNP 30
587 6BVJ GNP 30
588 6BVM GNP 30
589 6D5E GNP 30
590 6D5M GNP 30
591 6BVK GNP 30
592 6D56 GNP 30
593 6D5H GNP 30
594 6D59 GNP 30
595 6BVL GNP 30
596 6D5G GNP 30
597 6BVI GNP 30
598 6D5V GNP 30
599 1NVV GNP 30
600 3CPJ GDP 30
601 1T5C ADP 30
602 5IRC GDP 30
603 2G77 GDP 30
604 3A1S GDP 30
605 2O66 FLC 30
606 3H86 AP5 31.7708
607 5UWH GNP 31.8182
608 5H68 AGS 32
609 1S3G AP5 32
610 4PPF FLC 32
611 1NRJ GTP 32
612 5G41 AP5 32
613 5SZH GNP 32
614 6DEF GCP 32
615 3WYA GDP 32
616 3WY9 GDP 32
617 1QF9 C5P 32
618 1QF9 ADP 32
619 1QF9 ALF 32
620 4YS0 ADP 32
621 2QN6 GDP 33.3333
622 4TL6 ANP 34
623 3EZ2 ADP 34
624 3ZFD ANP 34
625 6BSX E7S 34
626 6BSX GDP 34
627 1K6M AGS 34
628 4GOJ GNP 34
629 3N9R TD3 34
630 2OG2 MLI 36
631 1FNN ADP 36
632 1IN4 ADP 36
633 4A4Z ANP 36
634 5K5Z ANP 36
635 1OFH ADP 36
636 6BC0 GSP 36
637 5FG3 GDP 36
638 1Q19 APC 36
639 1Y3A GDP 37.5
640 1AKY AP5 38
641 3FB4 AP5 38
642 1ZIN AP5 38
643 3TNF GNP 38
644 6G14 G4P 38
645 2B8W ALF 5GP 38
646 5L3S GNP 40
647 5L3S G 40
648 1CS4 GSP 40
649 5L3W GDP 40
650 3CGD FAD 40
651 3CGD NAD 40
652 3CGD COA 40
653 2QG6 NMN 40
654 5U32 GDP 42
655 5BN3 ADP 42
656 2BIF ANP 42
657 2BIF SIN 42
658 4HSE ADP 42
659 3DOE GTP 44
660 4D81 ADP 44
661 5ZB0 TYD 44
662 5ZB0 ADP 44
663 5Z69 AGS 46
664 5EXT ADP 46
665 1TU3 GNP 46.8354
666 5H67 ATP 48
667 3A4M ADP 48
668 3QKT ANP 48.2192
669 5AK0 8V1 50
670 5UWO GNP 50
Pocket No.: 2; Query (leader) PDB : 3QF7; Ligand: ANP; Similar sites found with APoc: 103
This union binding pocket(no: 2) in the query (biounit: 3qf7.bio3) has 31 residues
No: Leader PDB Ligand Sequence Similarity
1 4CU1 H4B 1.64384
2 4CFT H4B 1.64384
3 4XFR CIT 1.64384
4 5HQ8 SAH 1.64384
5 1GVF PGH 1.74825
6 1LDN FBP 1.89873
7 2DT9 THR 2.39521
8 5KXE 6Y2 2.46914
9 1P77 ATR 2.57353
10 2FJK 13P 2.62295
11 1IK4 PGH 2.63158
12 4DZ1 DAL 2.7027
13 1SQL GUN 2.73973
14 4NFE BEN 2.95359
15 2ZL4 ALA ALA ALA ALA 3.06122
16 2RC8 DSN 3.06122
17 1US5 GLU 3.50318
18 2XVM SAH 3.51759
19 5Z20 OXM 3.56164
20 4P83 U5P 3.84615
21 4FMS BDP 4
22 1C3V PDC 4
23 4NTM 2K8 4
24 6GN6 MAL 4
25 2BMB PMM 4.10959
26 5N1P 8GK 4.36893
27 2PS1 ORO 4.86726
28 1UJ5 5RP 5.20548
29 6AR9 3L4 5.51471
30 3KCC CMP 5.75342
31 3WLV AZA 5.76923
32 1V7Z CRN 5.76923
33 2P3V SRT 6
34 5IXB LGA 6
35 3LL9 ADP 6
36 3VPC ADP 6
37 3S5W NAP 6.0274
38 5SXS NIZ 6.57534
39 2JBH 5GP 7.11111
40 4OUJ LBT 7.81759
41 6A4R ASP 8
42 2OWZ CIT 8
43 3VPD BUA 8.54093
44 4PYA 2X3 8.69565
45 4TR9 38D 8.76712
46 3Q8U ADP 8.9172
47 4RJD TFP 9.09091
48 6AM8 TRP 9.59596
49 4QYS PLR 10
50 1UP7 G6P 10
51 4MZU COA 10
52 3VV5 SLZ 10
53 1I7Q BEZ 10
54 2UYQ SAM 10.137
55 4XMF HSM 10.8696
56 1O8B ABF 12
57 4IRP UDP 12
58 2C5S AMP 12
59 1DCP HBI 13.4615
60 5GZ9 MAN 14
61 3L6R MLI 14
62 3UDZ ADP 14
63 5JVB 2PO 14
64 3KP6 SAL 14
65 3G5S GSH 14
66 1MT6 SAH 14
67 2VHL GLP 16
68 4K6B GLU 16
69 1VAY AZA 16
70 1Y13 BIO 16
71 2ZC0 PMP 16
72 3X01 AMP 16
73 5F7U GLC GLC GLC GLC 16
74 4NOS H4B 18
75 3N71 SFG 18
76 5CPR SAM 18
77 5YLF BGC 18
78 4P86 5GP 19.6721
79 1L7N AF3 20
80 1QHH ATP 20
81 5A07 GDP 20
82 1L7N ALF 20
83 1XXA ARG 20
84 1HE1 AF3 20
85 1CM0 COA 20.8333
86 2HK9 ATR 22
87 4HZ0 1AV 22
88 4B2D FBP 24
89 5TDF 7A3 26
90 1N4K I3P 26
91 2Q0L NAP 26
92 5CZY SAM 28
93 3ITJ CIT 28
94 4GV8 DUP 28
95 4A59 AMP 30
96 2G77 AF3 30
97 1U3G ADP 30
98 4D1J DGJ 32
99 6ACS CIT 32
100 1P4V GLY 32
101 1QHG ATP 34
102 5WXU IAC 44
103 3QXY SAM 46.6667
Pocket No.: 3; Query (leader) PDB : 3QF7; Ligand: ANP; Similar sites found with APoc: 27
This union binding pocket(no: 3) in the query (biounit: 3qf7.bio3) has 30 residues
No: Leader PDB Ligand Sequence Similarity
1 1EYE PMM 1.78571
2 5N9X THR 1.91781
3 6H8S FSZ 3.65448
4 5HGZ MLA 4
5 1B4P GPS 4.14747
6 4FGC PQ0 4.84848
7 2AKO ADP 4.93151
8 4R29 SAM 5.35714
9 4XZ3 ACP 6
10 5VM6 9EG 6.56934
11 2IMG MLT 7.94702
12 1BW9 PPY 8
13 5HTL C2E 8
14 6GIU L69 8
15 1G7C 5GP 9.57447
16 1I7Q PYR 10
17 5ZRR 9J3 10
18 1R55 097 10
19 1M0S CIT 14
20 4NOS H2B 18
21 4N49 MGT 18
22 5FII PHE 22
23 4JEJ 1GP 24
24 3G6N MET ALA SER 28
25 3L6C MLI 28
26 5GG9 8GM 36
27 2WA2 SAM 42
Pocket No.: 4; Query (leader) PDB : 3QF7; Ligand: ANP; Similar sites found with APoc: 17
This union binding pocket(no: 4) in the query (biounit: 3qf7.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 4WOH 4NP 1.20482
2 4I4B NAD 2.46575
3 5A96 GTP 4.41767
4 3S5W FAD 6.0274
5 2F3R G5P 7.72947
6 3FPF MTA 8
7 3FPF TNA 8
8 2BHZ MAL 8.49315
9 5Z21 OXM 10
10 4B63 ORN 12
11 4B63 FAD 12
12 1D2N ANP 16
13 4KOT CE3 16
14 2A2C NG1 16
15 2A2C ADP 16
16 1G3M PCQ 26
17 1G3M A3P 26
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