Receptor
PDB id Resolution Class Description Source Keywords
3Q7G 2.3 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF E2 DOMAIN OF HUMAN AMYLOID PRECURSOR-LI 1 IN COMPLEX WITH SOS (SUCROSE OCTASULFATE) HOMO SAPIENS AMYLOID BETA PRECURSOR PROTEIN E2 DOMAIN ALZHEIMER-prime S DISEASIGNALING HEPARIN SIGNALING PROTEIN
Ref.: CRYSTAL STRUCTURE OF THE E2 DOMAIN OF AMYLOID PRECU PROTEIN-LIKE PROTEIN 1 IN COMPLEX WITH SUCROSE OCTA J.BIOL.CHEM. V. 286 29748 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GU4 YYJ D:1;
C:1;
E:1;
 Valid;
Valid;
Valid;
 none;
none;
none;
 submit data
974.737 n/a S(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3QMK 2.21 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE E2 DOMAIN OF APLP1 IN COMPLEX WITH HEXASACCHARIDE HOMO SAPIENS APP ALZHEIMER-prime S DISEASE CELLULAR ADHESION HEPARIN BRAINADHESION
Ref.: CRYSTAL STRUCTURE OF AMYLOID PRECURSOR-LIKE PROTEIN HEPARIN COMPLEX SUGGESTS A DUAL ROLE OF HEPARIN IN DIMERIZATION. PROC.NATL.ACAD.SCI.USA V. 108 16229 2011
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 3Q7G - GU4 YYJ n/a n/a
2 4RDA - IDS SGN IDS SGN UAP n/a n/a
3 3QMK - SGN IDS SGN IDS n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 3Q7G - GU4 YYJ n/a n/a
2 4RDA - IDS SGN IDS SGN UAP n/a n/a
3 3QMK - SGN IDS SGN IDS n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 3Q7G - GU4 YYJ n/a n/a
2 4RDA - IDS SGN IDS SGN UAP n/a n/a
3 3QMK - SGN IDS SGN IDS n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GU4 YYJ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 GU4 YYJ 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: GU4 YYJ; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3QMK; Ligand: SGN IDS SGN IDS; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3qmk.bio1) has 39 residues
No: Leader PDB Ligand Sequence Similarity
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