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Receptor
PDB id Resolution Class Description Source Keywords
3P4X 2.41 Å EC: 7.-.-.- HELICASE DOMAIN OF REVERSE GYRASE FROM THERMOTOGA MARITIMA THERMOTOGA MARITIMA TOPOISOMERASE DNA SUPERCOILING ARCHAEA HELICASE ISOMERAS
Ref.: THE CONFORMATIONAL FLEXIBILITY OF THE HELICASE-LIKE FROM THERMOTOGA MARITIMA REVERSE GYRASE IS RESTRICT TOPOISOMERASE DOMAIN. BIOCHEMISTRY V. 50 5816 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:800;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
CL B:1;
Invalid;
none;
submit data
35.453 Cl [Cl-]
MG A:799;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3P4X 2.41 Å EC: 7.-.-.- HELICASE DOMAIN OF REVERSE GYRASE FROM THERMOTOGA MARITIMA THERMOTOGA MARITIMA TOPOISOMERASE DNA SUPERCOILING ARCHAEA HELICASE ISOMERAS
Ref.: THE CONFORMATIONAL FLEXIBILITY OF THE HELICASE-LIKE FROM THERMOTOGA MARITIMA REVERSE GYRASE IS RESTRICT TOPOISOMERASE DOMAIN. BIOCHEMISTRY V. 50 5816 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 3P4X - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 3P4X - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 3P4X - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3P4X; Ligand: ADP; Similar sites found with APoc: 725
This union binding pocket(no: 1) in the query (biounit: 3p4x.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5O3Q CMP 0.726392
2 4NCN GTP 0.968523
3 5ZBC FAD 0.968523
4 1W4R TTP 1.02564
5 4TMZ GSP 1.15942
6 1QHG ATP 1.21065
7 1XKV ATP 1.45278
8 5IRN ADP 1.45278
9 1D2E GDP 1.51134
10 3PQC GDP 1.53846
11 4P4T GDP 1.66667
12 4ZKD GDP 1.69492
13 4DCT GDP 1.69492
14 1P9B GDP 1.69492
15 1V8K ANP 1.70732
16 3WR7 COA 1.76471
17 4LC1 GDP 1.78042
18 4FRZ ADP 1.81347
19 5ZBR ANP 1.86667
20 1U0J ADP 1.87266
21 1M7G ADX 1.89573
22 1M7G ADP 1.89573
23 1M7G AV2 1.89573
24 2ZFI ADP 1.91257
25 3HU3 AGS 1.93705
26 2GMV UN8 1.93705
27 3EZ2 ADP 1.93705
28 1NHX FTB 1.93705
29 2GMV PEP 1.93705
30 1NHX PEP 1.93705
31 4YJ1 ADP 1.93705
32 5JCP GDP ALF 1.93705
33 1YTM ATP 1.93705
34 4ZG4 VO4 ADP 1.93705
35 2CNE DFJ 1.97368
36 1G3M A3P 2.04082
37 1G3M PCQ 2.04082
38 1E2K TMC 2.1148
39 4GDX GLU 2.13904
40 5AK0 8V1 2.17918
41 4HSE ADP 2.17918
42 1R6B ADP 2.17918
43 4PFO ADP 2.17918
44 3T34 GDP 2.22222
45 4DDY DN6 2.28137
46 1T5C ADP 2.29226
47 1F9V ADP 2.30548
48 5BYK A3P 2.3166
49 5BYK OAQ 2.3166
50 2ZW5 COA 2.32558
51 5W76 GDP 2.33766
52 5EP2 AZU 2.34375
53 1U8Z GDP 2.38095
54 2WHX ADP 2.42131
55 5HR5 ADP 2.42131
56 2BIF ANP 2.42131
57 2BIF SIN 2.42131
58 1A4R GNH 2.42131
59 1A4R GDP 2.42131
60 2JLR ANP 2.42131
61 1EM6 NBG 2.42131
62 1NM5 NAP 2.46305
63 1NM5 NAD 2.46305
64 3QXC ATP 2.47934
65 3FYH ADP 2.48447
66 1ZRH A3P 2.55474
67 2WIC GNP 2.62172
68 4NSQ COA 2.63158
69 1RRC ADP 2.65781
70 5LLB 6YZ 2.6616
71 3LRE ADP 2.66344
72 4IDN GNP 2.66344
73 4DID GDP 2.66344
74 2QEN ADP 2.66344
75 1Z6T ADP 2.66344
76 5VGR GDP 2.66344
77 3RC3 ANP 2.66344
78 5HCN GCP 2.68199
79 2A9K GDP 2.69058
80 4AVB ACO 2.7027
81 2FLI DX5 2.72727
82 3KJI ADP 2.75591
83 2ZE7 DST 2.7668
84 2ZE7 AMP 2.7668
85 1T3D CYS 2.76817
86 3ORF NAD 2.78884
87 1GOJ ADP 2.8169
88 1S8F GDP 2.82486
89 4D81 ADP 2.82686
90 2J0V GDP 2.83019
91 1SVK ALF GDP 2.83286
92 5CK5 GDP 2.8481
93 2OOR TXP 2.87356
94 6FA4 GNP 2.89017
95 5FHD ADP ALF 2.90557
96 1BH2 GSP 2.90557
97 1G41 ADP 2.90557
98 3BOS CDP 2.90557
99 5FTB ANP 2.90557
100 1WDT GTP 2.90557
101 2OM2 GDP 2.90557
102 1Y3A GDP 2.90557
103 5I34 GDP 2.90557
104 5EE5 GTP 2.92398
105 3FKQ ATP 2.94906
106 2CBZ ATP 2.95359
107 1V0C KNC 2.9703
108 1V0C ACO 2.9703
109 3COB ADP 2.98103
110 2QG6 NMN 3.01508
111 4QOS ADP 3.01887
112 3T1O GDP 3.0303
113 2GDJ ANP 3.0303
114 4L2I FAD 3.04183
115 2FNA ADP 3.08123
116 3N5C GDP 3.08642
117 3PCR GTP 3.08642
118 3A1S GDP 3.10078
119 1R2Q GNP 3.1477
120 5M04 GDP 3.1477
121 2GKS ADP 3.1477
122 5ZXD ATP 3.1477
123 5FG3 GDP 3.1477
124 3QKT ANP 3.1477
125 2FAH GDP 3.1477
126 4ITR GDP 3.1477
127 3MJH GTP 3.1477
128 3CV2 OXL 3.1477
129 4ITM ATP 3.1746
130 1OJ4 ANP 3.18021
131 1AKY AP5 3.18182
132 1NJF ADP 3.2
133 1NJF AGS 3.2
134 5H68 AGS 3.23529
135 3EC1 GDP 3.25203
136 4TTQ ATP 3.25581
137 1IN4 ADP 3.29341
138 2OZE AGS 3.3557
139 1NY5 ADP 3.35917
140 3E5H GNP 3.37079
141 1YQT ADP 3.38983
142 4NON GDP 3.38983
143 3GDN MXN 3.38983
144 2WOJ ADP ALF 3.38983
145 3QWI NAP 3.38983
146 1JJV ATP 3.39806
147 2ORV 4TA 3.4188
148 2XTN GTP 3.4188
149 1KO8 6PG 3.42857
150 2QZ4 ADP 3.43511
151 2OBM ADP 3.45821
152 4UTG ANP 3.46821
153 2XT3 ADP 3.48837
154 5Z69 AGS 3.49462
155 4D9C PMP 3.50877
156 5H7K GDP 3.52645
157 5ZB0 ADP 3.53535
158 5ZB0 TYD 3.53535
159 4LJ9 ACP 3.53982
160 5G3Y ADP 3.53982
161 2Y65 ADP 3.56164
162 3GJ4 GDP 3.61991
163 3GJ7 GDP 3.61991
164 3GJ0 GDP 3.61991
165 3GJ3 GDP 3.61991
166 3GJ8 GDP 3.61991
167 3GJ5 GDP 3.61991
168 2DPY ADP 3.63196
169 6AU6 GDP 3.63196
170 4J0Q GDP 3.63196
171 1NN5 ANP 3.63196
172 1NN5 2DT 3.63196
173 5LTJ ADP 3.63196
174 4R43 GDP 3.63196
175 4ZDJ UTP 3.63196
176 1G6O ADP 3.63636
177 2AWN ADP 3.67454
178 3T12 GDP ALF 3.67647
179 1ZIN AP5 3.68664
180 3CH5 GDP 3.7037
181 5BXQ GDP 3.7037
182 2C77 GNP 3.7037
183 2C78 GNP 3.7037
184 2VVG ADP 3.71429
185 4RZ3 ADP 3.72881
186 5DI3 GNP 3.78378
187 5GOE GDP 3.79147
188 1NRJ GTP 3.79747
189 2R42 FPS 3.79747
190 3FWY ADP 3.82166
191 3PE2 E1B 3.85757
192 4FCW ADP 3.85852
193 1MR3 G3D 3.8674
194 3SFV GDP 3.8674
195 5YV5 ADP 3.87409
196 1DAR GDP 3.87409
197 1OS1 PYR 3.87409
198 1OS1 ATP 3.87409
199 2C9O ADP 3.87409
200 4GID 0GH 3.87409
201 2BME GNP 3.87409
202 3TE4 ACO 3.87409
203 4KVA GTP 3.8835
204 2JAQ DCP 3.90244
205 1GWN GTP 3.90244
206 4Q1A UDP 3.92857
207 4Q1A 2XZ 3.92857
208 4U5X GNP 3.93258
209 5SZH GNP 3.94089
210 4M9Q GNP 3.96476
211 1UJ2 C5P 3.96825
212 1UJ2 ADP 3.96825
213 6G96 ACO 3.97727
214 2GCO GNP 3.9801
215 2GCN GDP 3.9801
216 1WF3 GNP 3.98671
217 1FQK GDP 4
218 1TAD ALF 4.01235
219 1TAD GDP 4.01235
220 2F9L GDP 4.0201
221 3SXN COA 4.02844
222 1F6B GDP 4.0404
223 1AKV FMN 4.08163
224 1XP8 AGS 4.09836
225 1X6V ADP 4.11622
226 1FZQ GDP 4.11622
227 1SKQ GDP 4.11622
228 1MKY GDP 4.11622
229 2ZR9 DTP 4.11622
230 3ZFD ANP 4.11622
231 1IHU AF3 4.11622
232 1IHU ADP 4.11622
233 4GOJ GNP 4.11622
234 3TKL GTP 4.11622
235 5ECP MET 4.11622
236 5ECP JAA 4.11622
237 5ECP ATP 4.11622
238 1QF9 C5P 4.12371
239 1QF9 ALF 4.12371
240 1QF9 ADP 4.12371
241 4NU0 AP5 4.14747
242 1I4D GDP 4.16667
243 1BO4 COA 4.16667
244 1OIV GDP 4.18848
245 1OIX GDP 4.18848
246 1P72 ADP 4.19162
247 5IFS ADP 4.21941
248 3A4M ADP 4.23077
249 3TK1 GDP 4.24242
250 3DOE GTP 4.24242
251 2WJG GDP 4.25532
252 3SBD GNP 4.27807
253 3BD9 A3P 4.28571
254 1MH1 GNP 4.30108
255 5IRC GDP 4.30108
256 5HPY GDP 4.32432
257 6BCB GSP 4.32432
258 3RWO GDP 4.32432
259 1YZN GNP 4.32432
260 1KMQ GNP 4.34783
261 1OE0 TTP 4.34783
262 4NTO 1PW 4.34783
263 6A20 ADP 4.35835
264 1LVK MNT BEF 4.35835
265 2NCD ADP 4.35835
266 4OHY ANP 4.35835
267 3WXM GTP 4.35835
268 3VMF GTP 4.35835
269 1IWE IMP 4.35835
270 5KSP GDP 4.35835
271 2A2C ADP 4.35835
272 2A2C NG1 4.35835
273 4V36 LYN 4.35835
274 3QVV 3QV 4.35835
275 3QVV A3P 4.35835
276 5OEC GDP 4.37158
277 4BFW ZVW 4.40252
278 1UKZ ADP 4.4335
279 3H4S ADP 4.44444
280 4XOI GTP 4.44444
281 5X40 ACP 4.45205
282 5JCZ GDP 4.46927
283 4NE2 ADP 4.49102
284 4NE2 SH2 4.49102
285 2FJU GSP 4.49438
286 1FP6 ADP 4.49827
287 4LX0 BEF GDP 4.51977
288 1TX4 ALF GDP 4.51977
289 3B5J 12D 4.52675
290 1OXV ANP 4.53258
291 1LVG ADP 4.54545
292 4BQS K2Q 4.54545
293 4BQS ADP 4.54545
294 1WA5 GTP 4.54545
295 1HE1 GDP 4.54545
296 2IS6 ADP 4.55882
297 2BNE U5P 4.56432
298 3NKV GNP 4.57143
299 3NHB ADP 4.57516
300 1VHT BA3 4.58716
301 4LHW GNP 4.5977
302 3TNF GNP 4.5977
303 1B0U ATP 4.60048
304 5VHC BEF ADP 4.60048
305 3WY9 GDP 4.60048
306 3WYA GDP 4.60048
307 1Z83 AP5 4.60048
308 2WMO GTP 4.60048
309 2CE7 ADP 4.60048
310 1SVI GDP 4.61538
311 1Q20 A3P 4.68227
312 1Q20 PLO 4.68227
313 3LXR GDP 4.6875
314 2VB6 ADP BEF 4.69799
315 1G4U GDP 4.69974
316 1G16 GDP 4.70588
317 4WZA ACP 4.71014
318 4WZA ADP 4.71014
319 2A5J GDP 4.71204
320 5OCG GNP 4.7619
321 4QRH 0O2 4.7619
322 5UQW GDP 4.7619
323 5K5Z ANP 4.77707
324 3MD0 GDP 4.78873
325 4R98 GNH 4.79705
326 2WJH GDP 4.81928
327 2WJH FLC 4.81928
328 4WZ6 ATP 4.82759
329 2VZZ SCA 4.84262
330 6DEF GCP 4.85933
331 2CHG ANP 4.86726
332 1UPR 4IP 4.87805
333 4U00 ADP 4.91803
334 1KY3 GDP 4.94506
335 5KSZ GCP 4.95283
336 3IIJ ADP 5
337 1DS6 GDP 5
338 1XMV ADP 5.05618
339 1H74 ADP 5.06757
340 2Q2Y ADP 5.08475
341 2Q2Y MKR 5.08475
342 4IHQ ADP 5.08475
343 1FNN ADP 5.08475
344 3FB4 AP5 5.09259
345 1W5T ADP 5.09709
346 1W5T ANP 5.09709
347 4PX9 ADP 5.13699
348 1Z0A GDP 5.17241
349 5YGE ACO 5.17241
350 5YGE GLU 5.17241
351 2B8W ALF 5GP 5.18293
352 1SQ5 ADP 5.19481
353 4QM7 GTP 5.26316
354 6FHO FAD 5.26316
355 5WDR GNP 5.26316
356 1ZC3 GNP 5.30973
357 1YVD GNP 5.32544
358 3Q85 GNP 5.32544
359 5XDR ADP 5.32688
360 4GOX A3P 5.32688
361 5TVJ COA 5.32688
362 3V2U ATP 5.32688
363 1IBR GNP 5.32688
364 1YRB GDP 5.34351
365 3DUV KDO 5.34351
366 1ZUI SKM 5.35714
367 2GWH A3P 5.36913
368 5G41 AP5 5.38117
369 3W5J GDP 5.39216
370 6G14 G4P 5.44218
371 2VBQ BSJ 5.45455
372 3UIE ANP 5.5
373 6CRK GDP 5.50725
374 1S3G AP5 5.52995
375 4MKF AP5 5.52995
376 4MKG AP5 5.52995
377 4RD0 GDP 5.54217
378 4DKX GDP 5.55556
379 2G77 GDP 5.55556
380 5WC2 ADP 5.56901
381 3CPJ GDP 5.56901
382 2BCG GDP 5.56901
383 5EXT ADP 5.56901
384 1M7B GTP 5.56901
385 1GP2 GDP 5.58824
386 3B7G ANP 5.65217
387 4KFU ACP 5.66038
388 2WKQ GTP 5.72289
389 4HUT ATP 5.75916
390 4WOP CTP 5.77778
391 1DAK ADP 5.80357
392 1DAK DPU 5.80357
393 4PJ3 ANP 5.81114
394 3FVQ ATP 5.81114
395 4H1V GNP 5.81114
396 5MEX SZZ 5.81114
397 5MEX PAP 5.81114
398 6MA3 JAJ 5.81114
399 5KUT GDP 5.82011
400 1Z06 GNP 5.82011
401 2B8T THM 5.8296
402 4YMU ATP 5.83333
403 4CVN ADP 5.83942
404 1W0J ADP 5.88235
405 1W0J ADP BEF 5.88235
406 1EK0 GNP 5.88235
407 3RAB GNP 5.91716
408 2FH5 GTP 5.94595
409 1L2T ATP 5.95745
410 2CDN ADP 5.97015
411 2D2F ADP 6
412 2CK3 ANP 6
413 2CK3 ADP 6
414 6B8B ADP 6.0241
415 3IO3 ADP 6.03448
416 3TBK ANP 6.05327
417 5O74 GDP 6.09137
418 3DEF GDP 6.10687
419 2PZE ATP 6.11354
420 3OVR 5SP 6.14035
421 1J99 AND 6.14334
422 1JJ7 ADP 6.15385
423 5UIV ADP 6.1674
424 1NU4 MLA 6.18557
425 4GBM A3P 6.19195
426 5L3W GDP 6.20915
427 3GDH MGP 6.22407
428 4V03 ADP 6.22568
429 3H86 AP5 6.25
430 1D2N ANP 6.25
431 2F3R G5P 6.28019
432 2ZJ5 ADP 6.2954
433 1F5N GNP 6.2954
434 1KK1 GNP 6.2954
435 5XC5 GTP 6.2954
436 4TL6 ANP 6.32411
437 2Z5F A3P 6.37584
438 2ODE ALF GDP 6.38298
439 3E70 GDP 6.40244
440 1Z08 GNP 6.47059
441 3CNL GNP 6.48855
442 1Y63 ADP 6.52174
443 3DZD ADP 6.52174
444 5N69 ADP 6.53266
445 3ZIA ADP 6.53753
446 4IOK XPO 6.53753
447 4IOK ADP 6.53753
448 3ZIA ATP 6.53753
449 3Q9L ATP 6.53846
450 5M7P ADP 6.60793
451 1G6H ADP 6.61479
452 3AB3 GDP 6.62983
453 1ZCB GDP 6.62983
454 2IYL GDP 6.69014
455 1YZG GDP 6.70391
456 1F2U ATP 6.71141
457 2OFW ADX 6.73077
458 2A5F GTP 6.73575
459 3GJX GTP 6.77966
460 4E03 ADP 6.79612
461 2OD9 A1R NCA 6.81818
462 2QQF A1R 6.81818
463 1I1D 16G 6.8323
464 1RM6 FAD 6.8323
465 1I1D COA 6.8323
466 1RYH GNP 6.89655
467 3MGB PAP 6.89655
468 4X8O AP5 7.00935
469 2B4B COA 7.01754
470 2B4D COA 7.01754
471 6B4K ANP 7.02179
472 4A4Z ANP 7.02179
473 2XAU ADP 7.02179
474 1K6M AGS 7.02179
475 1SZD APR 7.07071
476 3CX8 GSP 7.10059
477 4P3Y GDP 7.1066
478 3U6B GDP 7.1066
479 5JBQ GDP 7.1066
480 4G5G GDP 7.1066
481 3U6K GDP 7.1066
482 4PC3 GDP 7.1066
483 1D8T GDP 7.12468
484 2BVN GNP 7.12468
485 3QBT GNP 7.14286
486 3Q72 GNP 7.22892
487 1OYY AGS 7.26392
488 5MZN ADP 7.26392
489 5H7J GCP 7.26392
490 4XGU ADP 7.26392
491 2JJK R15 7.26392
492 5I0H ADP BEF 7.26392
493 3KC1 2T6 7.26392
494 1M2O GNP 7.36842
495 4JLV ADP 7.43494
496 1G7C 5GP 7.44681
497 5IRR GSP 7.46753
498 4HI0 GDP 7.48031
499 2EFE GNH 7.49064
500 2V7Q ATP 7.50605
501 4D0N GDP 7.50605
502 2V7Q ADP 7.50605
503 2ZTS ADP 7.50605
504 5L3R GCP 7.50853
505 2ZEJ GDP 7.6087
506 1QF5 GDP 7.65661
507 1QF5 RPL 7.65661
508 1S7N COA 7.69231
509 2RFI SAH 7.7193
510 1VG0 GDP 7.72947
511 1VG8 GNP 7.72947
512 1BG2 ADP 7.74818
513 4PPF FLC 7.74818
514 4AG5 ADP 7.74818
515 3WYG GTP 7.74818
516 1OFH ADP 7.74818
517 2GK6 ADP 7.74818
518 3EWA ANP 7.74818
519 3REF GDP 7.74818
520 1RJ9 GCP 7.74818
521 2X7I CIT 7.79221
522 1NF3 GNP 7.8125
523 4OI4 ATP 7.82609
524 5NM7 GLY 7.89474
525 2EW1 GNP 7.9602
526 4B47 GDP 7.98898
527 1NST A3P 8
528 3ZQ6 ADP ALF 8.02469
529 5T2U NAP 8.06452
530 2OG2 MLI 8.07799
531 4YLG GDP 8.09249
532 2RCN GDP 8.10056
533 3RLF ANP 8.10811
534 2IXE ATP 8.11808
535 3WYF GTP 8.21918
536 3M1I GTP 8.21918
537 2QQ0 THM 8.23245
538 2QQ0 ANP 8.23245
539 2QQ0 TMP 8.23245
540 2QQ0 ADP 8.23245
541 2ZPA ADP 8.23245
542 6EDV COA 8.24742
543 1JI0 ATP 8.33333
544 5L3V GDP 8.3612
545 2PEZ GGZ 8.37989
546 2PEZ DAT 8.37989
547 5L3S GNP 8.38926
548 5TUZ SAM 8.42912
549 5TUZ 7L6 8.42912
550 1Z0J GTP 8.47458
551 1W7J ADP BEF 8.60927
552 1VG1 GDP 8.64865
553 1VG9 GDP 8.64865
554 4UXH T5A 8.69565
555 1X1R GDP 8.71671
556 1OW3 GDP 8.71671
557 3TMK T5A 8.7963
558 2O66 FLC 8.88889
559 1XX6 ADP 8.90052
560 6CS8 F9Y 8.91089
561 1Z0F GDP 8.93855
562 2NGR GDP 8.95884
563 1GRN GDP 8.95884
564 4KAX GTP 8.95884
565 5BQ5 ADP BEF 8.99471
566 1ZD9 GDP 9.04255
567 5U32 GDP 9.20097
568 3VX3 ADP 9.27419
569 1G7S GDP 9.4431
570 4LYA ATP 9.4431
571 4IEE AGS 9.4431
572 3B9Q MLI 9.60265
573 2XTZ GSP 9.60452
574 1SVM ATP 9.81432
575 5TIV A3P 9.88142
576 1T8U UAP SGN IDS SGN 9.92647
577 1T8U A3P 9.92647
578 5W7Q GDP 9.92736
579 2YOH WMJ 10
580 3QF7 ANP 10
581 4BAS GNP 10.0503
582 1Z0K GTP 10.1449
583 4C4P GNP 10.2804
584 3BFX A3P 10.4116
585 2BEK ATP 10.4116
586 5UWP GNP 10.4895
587 5UWS GNP 10.4895
588 5DI9 GNP 10.4895
589 1R0X ATP 10.4895
590 5UWO GNP 10.4895
591 5UWW GNP 10.4895
592 6CIT GNP 10.4895
593 5UWH GNP 10.4895
594 5UWI GNP 10.4895
595 5DHF GNP 10.4895
596 5UWU GNP 10.4895
597 5DIF GNP 10.4895
598 5UWT GNP 10.4895
599 5UWJ GNP 10.4895
600 2X77 GDP 10.582
601 2Y8E GNP 10.6145
602 4YC7 GNP 10.6538
603 5T0K SAM 10.6538
604 1ZJ6 G3D 10.6952
605 4HAT GNP 10.7143
606 2QTV GNP 10.7784
607 5W75 GDP 10.8959
608 2HV8 GTP 10.9375
609 3IUY AMP 10.9649
610 2KIN ADP 11
611 2FFQ GSP 11.1111
612 1YZQ GNP 11.1765
613 1O3Y GTP 11.4458
614 1J2J GTP 11.4458
615 3KTA AP5 11.5607
616 5J1J ANP 11.5789
617 1RE0 GDP 11.5854
618 1ION ADP 11.6223
619 2PL3 ADP 11.8644
620 1G3Q ADP 11.8644
621 2D7D ADP 11.8644
622 1HTW ADP 12.0253
623 1QHH ATP 12.1065
624 2C5L GTP 12.1387
625 5J1S ATP 12.1951
626 1CS4 GSP 12.2642
627 4K81 GTP 12.2807
628 6GAQ FMN 12.3377
629 5GVR LMR 12.3932
630 5E95 GDP 12.5
631 5UPK GNP 12.5
632 6BVM GNP 12.5749
633 6BVK GNP 12.5749
634 6D5E GNP 12.5749
635 6D5G GNP 12.5749
636 6BVI GNP 12.5749
637 6BVL GNP 12.5749
638 6D5H GNP 12.5749
639 1LFD GNP 12.5749
640 6D5M GNP 12.5749
641 6D5V GNP 12.5749
642 6D59 GNP 12.5749
643 6D56 GNP 12.5749
644 6D55 GNP 12.5749
645 6D5L GNP 12.5749
646 6D5J GNP 12.5749
647 6BVJ GNP 12.5749
648 3DDC GNP 12.6506
649 1NVV GNP 12.6506
650 1CLU DBG 12.6506
651 1WQ1 GDP 12.6506
652 2UZI GTP 12.6506
653 3DKP ADP 12.6531
654 4ZI2 GNP 12.782
655 1XEX ATP 12.7907
656 3BER AMP 12.8514
657 5MVR ADP 12.963
658 2J59 GTP 13.0952
659 4TMK T5A 13.1455
660 1WWZ ACO 13.2075
661 4KBF AMP 13.4247
662 4KVG GTP 13.6905
663 1R4A GNP 13.7255
664 4HDO GNP 13.7725
665 3X1Z GNP 13.7725
666 4HDQ GNP 13.7725
667 2HT6 GDP 13.8015
668 2CJW GDP 14.0436
669 2W83 GTP 14.2857
670 1Z2A GDP 14.2857
671 3BC1 GNP 14.359
672 1B7T ADP 14.7436
673 1S9D GDP 14.7783
674 5KDO GDP 14.8649
675 1KAO GDP 14.9701
676 6FAA ADP 15.0121
677 1GOT GDP 15.0685
678 3AQ4 GDP 15.2174
679 5WRJ A3P 15.2542
680 5WRI A3P 15.2542
681 4XTR ADP 15.6682
682 4XTR ATP 15.6682
683 4XVU ATP 15.6682
684 5LB3 ADP 15.7385
685 1CR1 TTP 15.9806
686 2W2X GSP 16.129
687 3T5G GDP 16.4474
688 1KK8 BEF ADP 16.5468
689 2D7C GTP 16.6667
690 1FQJ GDP 16.6667
691 5H67 ATP 16.707
692 5BN3 ADP 17.1913
693 1GUA GNP 17.284
694 3KUD GDP 17.284
695 5Z2M GTP 17.3913
696 2GJ8 ALF GDP 17.4419
697 5WLB GNP 17.6471
698 1UAD GNP 18.1818
699 1VKJ A3P 18.2456
700 3KV8 FAH 18.705
701 2I4I AMP 19.1283
702 1PUJ GNP 19.1489
703 6C90 ADP 19.3705
704 6AIC AMP 19.6262
705 5LEF GTP 19.697
706 1SQL GUN 19.863
707 6BSX GDP 20.2247
708 6BSX E7S 20.2247
709 3MWL 8OX 21.256
710 1CXZ GSP 23.2558
711 2RGX AP5 23.301
712 4XSH GSP 24.2009
713 2HCJ GDP 24.3243
714 4YDS ATP 24.5614
715 1KSH GDP 25
716 2QN6 GDP 25.8065
717 6BCA GSP 25.8278
718 3ZS9 ADP ALF 26.3158
719 2VOH CIT 26.9231
720 4D0G GTP 27.5362
721 5YT0 GDP 28.5714
722 5UWR GNP 29.6296
723 1E96 GTP 30.0493
724 6BC0 GSP 32
725 5UWQ GNP 36.3636
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