Receptor
PDB id Resolution Class Description Source Keywords
3OBQ 1.4 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A PSAP PEPTIDE HOMO SAPIENS PROTEIN TRANSPROT UBIQUITIN BINDING PROTEIN TRANSPORT
Ref.: CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS OF THE ESC /HIV-1 GAG PTAP INTERACTION. STRUCTURE V. 18 1536 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PRO THR PRO SER ALA PRO VAL PRO LEU B:346;
 Valid;
 none;
 Kd = 290 uM
878.038 n/a O=C([...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3OBU 1.6 Å NON-ENZYME: TRANSCRIPT_TRANSLATE CRYSTAL STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A PTAP PEPTIDE HOMO SAPIENS PROTEIN TRANPORT UBIQUITIN HIV-1 GAG PROTEIN TRANSPORT
Ref.: CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS OF THE ESC /HIV-1 GAG PTAP INTERACTION. STRUCTURE V. 18 1536 2010
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 308 families.
1 3OBQ Kd = 290 uM PRO THR PRO SER ALA PRO VAL PRO LEU n/a n/a
2 3OBU Kd = 50 uM PRO GLU PRO THR ALA PRO PRO GLU GLU n/a n/a
3 3OBX Kd = 130 uM PRO GLU ALA THR ALA PRO PRO GLU GLU n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 266 families.
1 3OBQ Kd = 290 uM PRO THR PRO SER ALA PRO VAL PRO LEU n/a n/a
2 3OBU Kd = 50 uM PRO GLU PRO THR ALA PRO PRO GLU GLU n/a n/a
3 3OBX Kd = 130 uM PRO GLU ALA THR ALA PRO PRO GLU GLU n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 220 families.
1 3OBQ Kd = 290 uM PRO THR PRO SER ALA PRO VAL PRO LEU n/a n/a
2 3OBU Kd = 50 uM PRO GLU PRO THR ALA PRO PRO GLU GLU n/a n/a
3 3OBX Kd = 130 uM PRO GLU ALA THR ALA PRO PRO GLU GLU n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: PRO THR PRO SER ALA PRO VAL PRO LEU; Similar ligands found: 42
No: Ligand ECFP6 Tc MDL keys Tc
1 PRO THR PRO SER ALA PRO VAL PRO LEU 1 1
2 PRO GLU PRO THR ALA PRO PRO GLU GLU 0.5 0.935484
3 VAL PRO LEU 0.48913 0.803279
4 ASN LEU VAL PRO SER VAL ALA THR VAL 0.487805 0.920635
5 PRO GLU ALA THR ALA PRO PRO GLU GLU 0.483871 0.935484
6 PRO SER TYR SEP PRO THR SEP PRO SER 0.473282 0.791667
7 SER SER GLY LYS VAL PRO LEU 0.466667 0.919355
8 SER ALA GLU PRO VAL PRO LEU GLN LEU 0.464567 0.951613
9 THR THR ALA PRO SER LEU SER GLY LYS 0.461538 0.967742
10 SER PRO SER PRO SER PRO SER PRO SER PRO 0.45098 0.868852
11 PRO ALA PRO PHE ALA SER ALA 0.444444 0.888889
12 ASN LEU VAL PRO THR VAL ALA THR VAL 0.443548 0.888889
13 ASN LEU VAL PRO VAL VAL ALA THR VAL 0.44 0.888889
14 PRO SEP LEU PRO DVA 60H 0.43609 0.777778
15 LYS LEU THR PRO LEU CYS VAL THR LEU 0.434109 0.935484
16 SER SER GLY LYS VAL PRO LEU SER 0.432 0.935484
17 GLU PTR LEU GLY LEU ASP VAL PRO VAL 0.431193 0.822581
18 GLY THR SER SER PRO SER ALA ASP 0.428571 0.887097
19 ALA MET ALA PRO ARG THR LEU LEU LEU 0.425373 0.816901
20 PRO GLY PRO LEU PRO ALA 0.424779 0.870968
21 ACE GLU VAL ASN ALA PRO VAL LPD 0.421488 0.873016
22 PRO PRO LEU ALA SER LYS 0.419355 0.95082
23 SER VAL PRO ILE 0.419048 0.903226
24 ILE PRO LEU THR GLU GLU ALA GLU LEU 0.414062 0.888889
25 ASN LEU VAL PRO GLN VAL ALA THR VAL 0.413534 0.888889
26 LEU PRO SER PHE GLU THR ALA LEU 0.413043 0.90625
27 THR PRO THR ARG ASP VAL ALA THR SER PRO 0.411765 0.867647
28 PRO ALA PRO PHE ALA ALA ALA 0.41129 0.793651
29 LYS GLY PRO PRO LEU PRO ARG PRO ARG VAL 0.408 0.776119
30 ASN LEU VAL PRO MET VAL ALA THR VAL 0.407407 0.835821
31 PRO ALA PRO PHE PRO ALA NH2 0.40708 0.777778
32 PRO PRO PRO VAL PRO PRO ARG ARG ARG ARG 0.404762 0.761194
33 VAL PRO LEU THR GLU ASP ALA GLU LEU 0.40458 0.903226
34 ALA ARG MLZ SER ALA PRO ALA THR 0.404412 0.842857
35 ASP SER THR THR PRO ALA PRO THR 0.40367 0.868852
36 VAL MET ALA PRO ARG ALA LEU LEU LEU 0.402985 0.746479
37 PRO GLN PTR ILE PTR VAL PRO ALA 0.401408 0.723684
38 ALA ASN SER ARG VAL PRO THR SER ILE ILE 0.4 0.852941
39 ALA PRO THR 0.4 0.819672
40 ALA VAL PRO ALA 0.4 0.770492
41 PRO MET GLN SER TPO PRO LEU 0.4 0.808219
42 SER ALA PRO ASP THR ARG PRO ALA 0.4 0.867647
Similar Ligands (3D)
Ligand no: 1; Ligand: PRO THR PRO SER ALA PRO VAL PRO LEU; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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