Receptor
PDB id Resolution Class Description Source Keywords
3NQ1 2.3 Å EC: 1.14.18.1 CRYSTAL STRUCTURE OF TYROSINASE FROM BACILLUS MEGATERIUM IN WITH INHIBITOR KOJIC ACID BACILLUS MEGATERIUM TYROSINASE TYPE3 COPPER PROTEINS BACILLUS MEGATERIUM OXIDOREDUCTASE KOJIC ACID OXIDOREDUCTASE-OXIDOREDUCTASE ICOMPLEX
Ref.: FIRST STRUCTURES OF AN ACTIVE BACTERIAL TYROSINASE COPPER PLASTICITY. J.MOL.BIOL. V. 405 227 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CU A:501;
A:502;
B:501;
B:502;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
 submit data
63.546 Cu [Cu+2...
KOJ A:1351;
B:1351;
 Valid;
Valid;
 none;
none;
 submit data
142.109 C6 H6 O4 C1=C(...
ZN A:503;
A:504;
A:505;
A:506;
A:507;
A:508;
A:509;
A:510;
B:503;
B:504;
B:505;
B:506;
B:507;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6QXD 2.32 Å EC: 1.14.18.1 CRYSTAL STRUCTURE OF TYROSINASE FROM BACILLUS MEGATERIUM WIT INHIBITOR IN THE ACTIVE SITE. BACILLUS MEGATERIUM TYROSINASE INHIBITOR LIGAND OXIDOREDUCTASE
Ref.: EXPLOITING THE 1-(4-FLUOROBENZYL)PIPERAZINE FRAGMEN DEVELOPMENT OF NOVEL TYROSINASE INHIBITORS AS ANTI-MELANOGENIC AGENTS: DESIGN, SYNTHESIS, STRUCTU INSIGHTS AND BIOLOGICAL PROFILE. EUR.J.MED.CHEM. V. 178 380 2019
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6QXD ic50 = 0.96 uM JKB C18 H17 F N4 O5 c1cc(ccc1C....
2 4P6R - TYR C9 H11 N O3 c1cc(ccc1C....
3 4P6S - DAH C9 H11 N O4 c1cc(c(cc1....
4 4P6T - YRL C8 H10 O2 c1cc(ccc1C....
5 5I3B Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
6 5I3A Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
7 3NQ1 - KOJ C6 H6 O4 C1=C(OC=C(....
8 6EI4 - B5N C19 H21 F N2 O Cc1ccccc1C....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6QXD ic50 = 0.96 uM JKB C18 H17 F N4 O5 c1cc(ccc1C....
2 4P6R - TYR C9 H11 N O3 c1cc(ccc1C....
3 4P6S - DAH C9 H11 N O4 c1cc(c(cc1....
4 4P6T - YRL C8 H10 O2 c1cc(ccc1C....
5 5I3B Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
6 5I3A Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
7 3NQ1 - KOJ C6 H6 O4 C1=C(OC=C(....
8 6EI4 - B5N C19 H21 F N2 O Cc1ccccc1C....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 6QXD ic50 = 0.96 uM JKB C18 H17 F N4 O5 c1cc(ccc1C....
2 4P6R - TYR C9 H11 N O3 c1cc(ccc1C....
3 4P6S - DAH C9 H11 N O4 c1cc(c(cc1....
4 4P6T - YRL C8 H10 O2 c1cc(ccc1C....
5 5I3B Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
6 5I3A Kd = 9 uM HQE C6 H6 O2 c1cc(ccc1O....
7 3NQ1 - KOJ C6 H6 O4 C1=C(OC=C(....
8 6EI4 - B5N C19 H21 F N2 O Cc1ccccc1C....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: KOJ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 KOJ 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: KOJ; Similar ligands found: 1495
No: Ligand Similarity coefficient
1 4XR 0.9846
2 717 0.9766
3 93K 0.9743
4 HX3 0.9730
5 DHB 0.9726
6 URF 0.9721
7 4HM 0.9716
8 EUG 0.9709
9 HBA 0.9704
10 4VP 0.9693
11 MR1 0.9690
12 4M4 0.9689
13 V55 0.9689
14 INO 0.9675
15 4JJ 0.9673
16 27Y 0.9671
17 ASO 0.9671
18 LDP 0.9671
19 MNM 0.9669
20 FBA 0.9663
21 2A9 0.9658
22 2HO 0.9652
23 GLC 0.9650
24 4NC 0.9650
25 AHR 0.9648
26 3DO 0.9643
27 4FA 0.9641
28 MZG 0.9638
29 BR9 0.9627
30 4HO 0.9627
31 3XX 0.9625
32 2MI 0.9622
33 5XC 0.9620
34 P92 0.9619
35 9TW 0.9618
36 AX7 0.9616
37 XIY 0.9616
38 G4D 0.9613
39 RIB 0.9613
40 DGJ 0.9612
41 NOY 0.9612
42 270 0.9608
43 WBU 0.9608
44 MWJ 0.9606
45 MCT 0.9602
46 XBZ 0.9601
47 C2B 0.9601
48 4A3 0.9598
49 NNO 0.9591
50 MYJ 0.9591
51 82I 0.9589
52 3HM 0.9588
53 IFL 0.9586
54 XX2 0.9585
55 FHB 0.9581
56 NOJ 0.9577
57 275 0.9575
58 JLZ 0.9574
59 5JC 0.9573
60 GAL 0.9572
61 G2F 0.9566
62 4CL 0.9563
63 2YU 0.9562
64 C2A 0.9557
65 5OB 0.9554
66 BSX 0.9554
67 Q88 0.9550
68 261 0.9550
69 P9P 0.9549
70 FPY 0.9549
71 JZ7 0.9548
72 42J 0.9548
73 JZ2 0.9547
74 ABV 0.9546
75 DFB 0.9546
76 BZX 0.9545
77 XM0 0.9542
78 2AC 0.9541
79 6AI 0.9539
80 2MP 0.9537
81 H8N 0.9537
82 TH0 0.9536
83 LCN 0.9536
84 CXF 0.9535
85 4ZE 0.9534
86 4JM 0.9532
87 CHB 0.9532
88 BZ3 0.9527
89 2LP 0.9527
90 PEA 0.9520
91 NIZ 0.9518
92 YRL 0.9515
93 XYD 0.9514
94 5MB 0.9509
95 34A 0.9507
96 A1U 0.9503
97 2BG 0.9503
98 AMC 0.9502
99 2K4 0.9500
100 PHB 0.9500
101 0R0 0.9500
102 F60 0.9497
103 ES9 0.9497
104 5MI 0.9494
105 GAB 0.9493
106 1P8 0.9492
107 1M2 0.9491
108 14O 0.9490
109 1MC 0.9490
110 3HB 0.9490
111 5H1 0.9489
112 RSO 0.9489
113 MWM 0.9488
114 3OC 0.9488
115 R2B 0.9487
116 ES0 0.9486
117 FP1 0.9486
118 DHK 0.9484
119 CWM 0.9483
120 4JL 0.9482
121 TM7 0.9481
122 1PT 0.9481
123 11S 0.9480
124 5MH 0.9480
125 1LN 0.9477
126 DHS 0.9477
127 F0J 0.9476
128 IHB 0.9472
129 SAL 0.9472
130 ICP 0.9469
131 PYD 0.9469
132 TDR 0.9468
133 2XX 0.9468
134 53C 0.9467
135 AEF 0.9467
136 BGC 0.9467
137 GYE 0.9465
138 IFM 0.9465
139 3ID 0.9463
140 HYA 0.9463
141 SYN 0.9459
142 HT4 0.9458
143 PEL 0.9456
144 2EC 0.9455
145 FK1 0.9454
146 VOH 0.9454
147 OVV 0.9454
148 HMU 0.9452
149 5UC 0.9451
150 JZ4 0.9451
151 F9Y 0.9450
152 FPI 0.9449
153 JZ3 0.9447
154 F31 0.9446
155 I3A 0.9446
156 IF7 0.9445
157 PHU 0.9445
158 ZXD 0.9441
159 XYP 0.9441
160 DMJ 0.9441
161 BE2 0.9441
162 H4N 0.9440
163 HMH 0.9440
164 ABN 0.9436
165 H7Y 0.9435
166 XQ0 0.9433
167 3NT 0.9432
168 ES6 0.9431
169 TLD 0.9430
170 24B 0.9430
171 NSP 0.9430
172 ET2 0.9427
173 OAA 0.9427
174 LXC 0.9427
175 23A 0.9425
176 FAN 0.9424
177 AC6 0.9424
178 3U4 0.9423
179 VNL 0.9421
180 8ZE 0.9421
181 HBX 0.9421
182 GIV 0.9418
183 4FS 0.9417
184 8WO 0.9417
185 SOE 0.9415
186 JB5 0.9414
187 DMD 0.9414
188 HY1 0.9414
189 Y8I 0.9413
190 T6C 0.9413
191 ES5 0.9411
192 JAE 0.9409
193 7HQ 0.9408
194 RBL 0.9408
195 NPO 0.9408
196 3AB 0.9403
197 AGK 0.9401
198 PRY 0.9400
199 43M 0.9400
200 EOL 0.9399
201 PBZ 0.9399
202 SYV 0.9398
203 CN0 0.9398
204 TH7 0.9397
205 1P7 0.9396
206 NBE 0.9396
207 NK 0.9395
208 1F1 0.9395
209 4XV 0.9395
210 ZZT 0.9395
211 8H8 0.9395
212 5VM 0.9394
213 P3K 0.9393
214 LYL 0.9393
215 PZI 0.9393
216 8S0 0.9393
217 RBJ 0.9392
218 SHA 0.9392
219 1MR 0.9391
220 QOS 0.9390
221 5RG 0.9390
222 4P5 0.9389
223 36R 0.9388
224 ES2 0.9388
225 2FG 0.9388
226 SKM 0.9383
227 0HO 0.9383
228 JFJ 0.9382
229 X0V 0.9382
230 WCE 0.9379
231 5NU 0.9379
232 AZF 0.9379
233 GXL 0.9378
234 BEZ 0.9378
235 CLW 0.9377
236 R8A 0.9377
237 2AQ 0.9375
238 7A8 0.9374
239 IFP 0.9372
240 RIP 0.9372
241 7MH 0.9372
242 K2T 0.9371
243 03V 0.9370
244 ISZ 0.9370
245 3Z7 0.9370
246 VGD 0.9368
247 FBB 0.9368
248 AFR 0.9368
249 NBZ 0.9368
250 OXZ 0.9367
251 282 0.9367
252 F05 0.9367
253 EKZ 0.9365
254 JND 0.9365
255 149 0.9365
256 AEH 0.9364
257 4SX 0.9363
258 LNR 0.9362
259 E7Z 0.9361
260 BEN 0.9361
261 OCH 0.9357
262 DHR 0.9357
263 COU 0.9356
264 FYU 0.9356
265 258 0.9356
266 IDH 0.9355
267 ADE 0.9354
268 PY7 0.9353
269 6RQ 0.9352
270 5QY 0.9352
271 8NY 0.9351
272 GLA 0.9351
273 PYJ 0.9351
274 R1X 0.9351
275 XYL 0.9350
276 RB5 0.9350
277 FUL 0.9348
278 PZA 0.9346
279 5HN 0.9345
280 DFU 0.9344
281 4ZC 0.9344
282 ISN 0.9343
283 JZ1 0.9343
284 H76 0.9343
285 BCU 0.9343
286 BML 0.9343
287 NCA 0.9343
288 KKN 0.9342
289 BAM 0.9342
290 B24 0.9341
291 APY 0.9341
292 PZM 0.9339
293 8WT 0.9339
294 4AA 0.9339
295 3HA 0.9339
296 4FH 0.9337
297 ABI 0.9337
298 BDP 0.9336
299 HPA 0.9336
300 CEE 0.9336
301 N2I 0.9335
302 5WV 0.9334
303 ALL 0.9334
304 G3F 0.9334
305 4JO 0.9332
306 PYF 0.9331
307 5M0 0.9331
308 4XS 0.9330
309 1DW 0.9330
310 9X7 0.9328
311 ES7 0.9328
312 286 0.9328
313 0HN 0.9328
314 DBH 0.9328
315 GTQ 0.9327
316 7W4 0.9324
317 GAF 0.9324
318 TPA 0.9324
319 RM1 0.9323
320 URA 0.9323
321 L99 0.9322
322 CFI 0.9322
323 PAB 0.9322
324 CRS 0.9322
325 DEN 0.9321
326 FBM 0.9321
327 7HP 0.9321
328 3Z8 0.9320
329 FA0 0.9319
330 IUR 0.9318
331 4CH 0.9318
332 FUC 0.9317
333 NYL 0.9316
334 NIO 0.9315
335 94B 0.9314
336 6PC 0.9314
337 2D0 0.9312
338 PBC 0.9312
339 7WG 0.9311
340 H42 0.9311
341 45L 0.9311
342 2ZM 0.9310
343 GDE 0.9310
344 1AB 0.9309
345 R8S 0.9308
346 IDM 0.9307
347 EDG 0.9307
348 ROR 0.9307
349 LGC 0.9306
350 URC 0.9306
351 FUF 0.9306
352 ASC 0.9305
353 9CL 0.9304
354 HBD 0.9303
355 826 0.9303
356 7MU 0.9303
357 XAN 0.9303
358 X6X 0.9302
359 F81 0.9300
360 4CS 0.9299
361 BTE 0.9299
362 MAN 0.9298
363 5B1 0.9297
364 SJ5 0.9297
365 GZL 0.9297
366 SS1 0.9296
367 42A 0.9295
368 BHO 0.9295
369 GCS 0.9294
370 3BZ 0.9294
371 YCP 0.9294
372 8TX 0.9292
373 9TZ 0.9292
374 EHM 0.9291
375 QUZ 0.9289
376 R9S 0.9289
377 5CU 0.9288
378 BZ2 0.9288
379 I1E 0.9287
380 FEH 0.9287
381 ORN 0.9286
382 3M0 0.9286
383 3DM 0.9285
384 HGQ 0.9285
385 XRG 0.9283
386 URQ 0.9282
387 3A9 0.9281
388 L3Q 0.9281
389 GIF 0.9281
390 NPY 0.9280
391 271 0.9280
392 5NI 0.9280
393 UNU 0.9280
394 54G 0.9280
395 HIO 0.9278
396 0MK 0.9278
397 4JU 0.9277
398 BNF 0.9277
399 LZ1 0.9276
400 PAC 0.9276
401 268 0.9275
402 HHA 0.9275
403 HPY 0.9274
404 J9T 0.9273
405 BP9 0.9272
406 Z82 0.9272
407 IMR 0.9272
408 26D 0.9271
409 BHA 0.9270
410 1Y6 0.9270
411 DOB 0.9270
412 2AL 0.9270
413 1GN 0.9269
414 3F0 0.9269
415 GLF 0.9267
416 2DR 0.9267
417 UYA 0.9266
418 2H5 0.9266
419 4M0 0.9265
420 2CK 0.9264
421 069 0.9264
422 6M4 0.9264
423 0P6 0.9264
424 8GC 0.9262
425 IND 0.9261
426 7N0 0.9261
427 6NT 0.9261
428 TBP 0.9260
429 BMA 0.9260
430 QDK 0.9259
431 PA1 0.9259
432 M1A 0.9258
433 LZM 0.9256
434 XYS 0.9256
435 4MA 0.9255
436 5RO 0.9255
437 A7W 0.9254
438 T9G 0.9254
439 RSF 0.9254
440 0R1 0.9253
441 JA8 0.9253
442 FA1 0.9253
443 JKE 0.9253
444 AC0 0.9251
445 GJZ 0.9250
446 HSM 0.9247
447 MLT 0.9246
448 BZF 0.9245
449 QSC 0.9244
450 2A7 0.9244
451 9DG 0.9243
452 FUB 0.9242
453 1LQ 0.9242
454 HDH 0.9241
455 67N 0.9241
456 MUC 0.9240
457 FE DB1 0.9239
458 PCA 0.9238
459 4HS 0.9238
460 DIN 0.9237
461 ZZ3 0.9237
462 5MK 0.9237
463 4ZA 0.9236
464 HSE 0.9236
465 S76 0.9236
466 4WL 0.9236
467 GLL 0.9236
468 GVH 0.9235
469 2CQ 0.9235
470 Z6J 0.9235
471 QY9 0.9234
472 FCA 0.9234
473 ABE 0.9234
474 4JT 0.9233
475 MRW 0.9233
476 TWO 0.9233
477 R8V 0.9233
478 4JN 0.9232
479 KTA 0.9231
480 3C4 0.9230
481 DAB 0.9229
482 ARA 0.9229
483 ORO 0.9228
484 SRT 0.9227
485 6FZ 0.9227
486 150 0.9227
487 3NY 0.9226
488 GLU 0.9225
489 TZE 0.9225
490 35C 0.9224
491 3PF 0.9224
492 4Z4 0.9223
493 FH2 0.9223
494 JAW 0.9223
495 14J 0.9222
496 NVA 0.9221
497 TSS 0.9221
498 1SQ 0.9220
499 LDU 0.9220
500 ICO 0.9220
501 51F 0.9219
502 6LW 0.9218
503 DIE 0.9217
504 DHY 0.9217
505 948 0.9217
506 GXY 0.9216
507 M6W 0.9216
508 LMR 0.9216
509 BNS 0.9213
510 MPI 0.9213
511 1WG 0.9213
512 GUN 0.9212
513 FDK 0.9211
514 JIF 0.9210
515 45C 0.9210
516 URP 0.9210
517 BZI 0.9208
518 5FX 0.9208
519 4SV 0.9208
520 HLR 0.9207
521 NTN 0.9207
522 VGL 0.9207
523 2MH 0.9207
524 5RN 0.9205
525 RNS 0.9205
526 M4T 0.9205
527 BRT 0.9203
528 5QX 0.9203
529 RAM 0.9203
530 HYP 0.9202
531 SS2 0.9202
532 SHG 0.9201
533 YIO 0.9201
534 1XX 0.9201
535 174 0.9200
536 URS 0.9199
537 N5J 0.9198
538 9EW 0.9197
539 25R 0.9197
540 VXX 0.9197
541 BPN 0.9195
542 XUL 0.9194
543 0RW 0.9193
544 IGA 0.9193
545 WOO 0.9193
546 PXY 0.9192
547 OTR 0.9192
548 64K 0.9192
549 FQI 0.9191
550 PCR 0.9190
551 FDB 0.9190
552 VNJ 0.9190
553 RNT 0.9189
554 KBG 0.9189
555 QSH 0.9189
556 JBH 0.9188
557 F9P 0.9187
558 TTL 0.9187
559 IOL 0.9186
560 SW7 0.9186
561 JB8 0.9185
562 AEG 0.9185
563 ICB 0.9185
564 SVD 0.9184
565 0CU 0.9184
566 284 0.9183
567 OK7 0.9182
568 JPZ 0.9181
569 E5X 0.9181
570 G3E 0.9180
571 M58 0.9179
572 HQE 0.9178
573 5SG 0.9178
574 TEO 0.9178
575 IV2 0.9178
576 SE2 0.9177
577 D48 0.9177
578 KJY 0.9177
579 D1X 0.9177
580 ARW 0.9176
581 7B4 0.9176
582 6M9 0.9175
583 54D 0.9175
584 5IQ 0.9175
585 MWP 0.9175
586 JDN 0.9174
587 J5I 0.9174
588 2CO 0.9174
589 AL0 0.9174
590 B55 0.9172
591 GLT 0.9171
592 10L 0.9169
593 BTY 0.9167
594 LG4 0.9166
595 ES1 0.9166
596 69O 0.9166
597 BE7 0.9165
598 IJZ 0.9165
599 UGC 0.9164
600 2HU 0.9164
601 THE 0.9164
602 HH5 0.9164
603 OHG 0.9164
604 ARB 0.9164
605 1LM 0.9163
606 DX4 0.9163
607 3R6 0.9163
608 9YL 0.9163
609 O72 0.9162
610 F4Z 0.9162
611 LRH 0.9162
612 TYL 0.9162
613 ZBT 0.9161
614 TZL 0.9161
615 6GU 0.9161
616 1P3 0.9161
617 J6W 0.9161
618 DIG 0.9161
619 290 0.9160
620 SR1 0.9160
621 B53 0.9160
622 32O 0.9160
623 DOR 0.9159
624 PNZ 0.9159
625 1NP 0.9158
626 75K 0.9157
627 4YS 0.9156
628 ADA 0.9155
629 NLE 0.9154
630 OXC 0.9154
631 2RH 0.9153
632 9MG 0.9153
633 6CS 0.9151
634 H3M 0.9150
635 MZW 0.9150
636 P72 0.9149
637 4NM 0.9149
638 ESP 0.9149
639 S2G 0.9148
640 FPN 0.9147
641 JZ9 0.9147
642 PLQ 0.9146
643 ILE 0.9146
644 4BZ 0.9146
645 6AP 0.9145
646 KUF 0.9145
647 XQG 0.9145
648 9DA 0.9144
649 DA1 0.9143
650 OHP 0.9143
651 24W 0.9141
652 6MP 0.9141
653 95Z 0.9141
654 5Q0 0.9140
655 3CH 0.9140
656 49F 0.9140
657 ONL 0.9139
658 5JQ 0.9139
659 HL5 0.9138
660 3HP 0.9138
661 6NI 0.9138
662 3SK 0.9138
663 XLS 0.9137
664 2HQ 0.9136
665 23W 0.9136
666 LT2 0.9135
667 GLY ALA 0.9134
668 A2F 0.9133
669 40E 0.9133
670 FOC 0.9133
671 G6D 0.9133
672 KT7 0.9132
673 RP7 0.9132
674 25W 0.9132
675 ADZ 0.9131
676 PYG 0.9131
677 FBJ 0.9130
678 CWS 0.9129
679 HQY 0.9129
680 FBW 0.9129
681 5JL 0.9129
682 K97 0.9129
683 MQN 0.9128
684 KDV 0.9127
685 4H2 0.9126
686 JBK 0.9126
687 FGZ 0.9126
688 0W8 0.9126
689 XCZ 0.9125
690 ODO 0.9124
691 GCU 0.9124
692 B3R 0.9123
693 GAG 0.9123
694 GOJ 0.9121
695 BCP 0.9121
696 SVN 0.9120
697 SWA 0.9120
698 YH7 0.9119
699 AMH 0.9119
700 3MB 0.9119
701 OVM 0.9119
702 51R 0.9119
703 TC7 0.9117
704 KMT 0.9117
705 AX3 0.9116
706 86J 0.9116
707 HEW 0.9116
708 9HX 0.9115
709 0CT 0.9115
710 SWD 0.9115
711 IP0 0.9115
712 RCO 0.9114
713 9ZE 0.9112
714 LNO 0.9112
715 15N 0.9110
716 FCR 0.9108
717 1DJ 0.9108
718 BDF 0.9108
719 MNN 0.9106
720 EV0 0.9105
721 E7S 0.9102
722 EA1 0.9101
723 DAS 0.9101
724 173 0.9101
725 HCS 0.9100
726 JBE 0.9100
727 CIG 0.9100
728 1WD 0.9100
729 4JQ 0.9098
730 M3T 0.9098
731 XAZ 0.9098
732 NMJ 0.9098
733 3IT 0.9098
734 M2K 0.9097
735 TIU 0.9097
736 FSG 0.9096
737 HHQ 0.9095
738 EMZ 0.9094
739 XBT 0.9093
740 FBS 0.9093
741 DEE 0.9091
742 34D 0.9091
743 M2H 0.9090
744 HIS 0.9090
745 IT2 0.9089
746 DYA 0.9088
747 BVF 0.9088
748 PAF 0.9087
749 ISD 0.9087
750 MBG 0.9086
751 PXL 0.9086
752 0JD 0.9086
753 KJU 0.9086
754 YHO 0.9086
755 2FY 0.9085
756 B57 0.9085
757 CRN 0.9084
758 IOM 0.9083
759 LG5 0.9082
760 Q6T 0.9082
761 MS9 0.9081
762 COI 0.9081
763 4YO 0.9080
764 UAN 0.9079
765 MAE 0.9079
766 OW4 0.9078
767 AS3 0.9077
768 4JP 0.9076
769 FOT 0.9076
770 8CM 0.9074
771 ASP 0.9074
772 AW5 0.9073
773 ASN 0.9072
774 AZG 0.9072
775 IPB 0.9072
776 XXR 0.9072
777 7WA 0.9071
778 HY3 0.9071
779 GTR 0.9070
780 R9Y 0.9070
781 NF3 0.9067
782 98J 0.9065
783 1DU 0.9065
784 LG3 0.9064
785 JFD 0.9062
786 TLA 0.9060
787 AH8 0.9060
788 HQJ 0.9060
789 259 0.9058
790 FBV 0.9058
791 KPL 0.9057
792 PM6 0.9057
793 A65 0.9057
794 OMD 0.9057
795 UY7 0.9057
796 4RW 0.9056
797 HH8 0.9056
798 QBM 0.9055
799 141 0.9054
800 KYD 0.9054
801 NEQ 0.9054
802 MRY 0.9053
803 3RK 0.9052
804 1XM 0.9050
805 3SL 0.9049
806 8GF 0.9048
807 8IG 0.9048
808 ANN 0.9048
809 HA5 0.9047
810 IT9 0.9047
811 8EZ 0.9047
812 K5W 0.9047
813 C2U 0.9047
814 263 0.9046
815 4J8 0.9046
816 KP6 0.9046
817 MED 0.9045
818 GOO 0.9045
819 94W 0.9044
820 MRZ 0.9043
821 CFP 0.9042
822 SN4 0.9041
823 42C 0.9041
824 AZA 0.9040
825 QMP 0.9039
826 BP1 0.9038
827 FCB 0.9038
828 ICF 0.9037
829 N8Y 0.9036
830 HZP 0.9036
831 4HC 0.9036
832 PRA 0.9035
833 JTH 0.9035
834 7VS 0.9034
835 12Q 0.9033
836 DTL 0.9033
837 QWN 0.9032
838 PE0 0.9031
839 VAH 0.9031
840 HX2 0.9031
841 AKH 0.9031
842 DE5 0.9030
843 I4B 0.9030
844 AKG 0.9030
845 LKA 0.9029
846 PRO 0.9028
847 7W1 0.9027
848 SF9 0.9026
849 DUC 0.9026
850 0TU 0.9025
851 JYD 0.9025
852 J9Q 0.9025
853 ECE 0.9025
854 4XH 0.9024
855 MFB 0.9024
856 TSU 0.9024
857 M1E 0.9024
858 J1Z 0.9023
859 QXW 0.9023
860 CYT 0.9023
861 LFR 0.9023
862 92K 0.9022
863 MET 0.9021
864 AZ9 0.9020
865 H62 0.9020
866 BOA 0.9019
867 GRE 0.9019
868 CTL 0.9018
869 UEG 0.9017
870 XX3 0.9017
871 SAN 0.9016
872 AAS 0.9016
873 AMS 0.9016
874 SX1 0.9016
875 HSO 0.9016
876 5WX 0.9016
877 AZ8 0.9015
878 B2J 0.9014
879 PMB 0.9014
880 DBX 0.9014
881 EDR 0.9013
882 RUU 0.9013
883 449 0.9012
884 5LA 0.9012
885 6F0 0.9012
886 ITN 0.9011
887 HPS 0.9011
888 7D2 0.9011
889 6M1 0.9011
890 IAC 0.9009
891 M3H 0.9006
892 5HY 0.9006
893 KJH 0.9005
894 HQD 0.9005
895 DHI 0.9005
896 47J 0.9005
897 5GU 0.9004
898 PBA 0.9002
899 PFB 0.9002
900 KBB 0.9001
901 XXG 0.9001
902 ZWZ 0.9001
903 7WV 0.9000
904 MXN 0.9000
905 ES4 0.8999
906 3AL 0.8998
907 UFV 0.8998
908 FRU 0.8998
909 1DV 0.8998
910 FB2 0.8997
911 4ME 0.8997
912 ESX 0.8997
913 ICC 0.8997
914 6UA 0.8997
915 AMG 0.8997
916 264 0.8996
917 DBJ 0.8996
918 PIY 0.8996
919 RHU 0.8996
920 PIM 0.8995
921 60P 0.8995
922 9RW 0.8993
923 PO6 0.8993
924 285 0.8993
925 HQ9 0.8992
926 RAT 0.8990
927 BEW 0.8990
928 4HP 0.8989
929 QIC 0.8989
930 7VJ 0.8989
931 TAR 0.8987
932 J9N 0.8987
933 M1Q 0.8986
934 92P 0.8985
935 FB1 0.8985
936 OVP 0.8984
937 9FE 0.8982
938 TTY 0.8982
939 ZB1 0.8982
940 Q24 0.8981
941 0LH 0.8981
942 SOR 0.8981
943 PKU 0.8980
944 OXQ 0.8980
945 JZ5 0.8979
946 GZ3 0.8979
947 PXM 0.8978
948 AHB 0.8977
949 7NI 0.8976
950 F4E 0.8975
951 GIO 0.8975
952 0W1 0.8974
953 12T 0.8973
954 M5K 0.8971
955 RM4 0.8971
956 CSS 0.8970
957 9FL 0.8970
958 HQT 0.8969
959 JXN 0.8969
960 KIV 0.8968
961 TGX 0.8967
962 15L 0.8967
963 EVA 0.8967
964 MBD 0.8966
965 PRZ 0.8964
966 GLN 0.8964
967 AQO 0.8963
968 3FH 0.8962
969 DIU 0.8962
970 E1T 0.8961
971 0N7 0.8961
972 3MG 0.8961
973 CWJ 0.8960
974 G5V 0.8959
975 SPV 0.8959
976 ALO 0.8958
977 SLS 0.8958
978 GBD 0.8957
979 CYS 0.8957
980 A29 0.8956
981 RMN 0.8955
982 9R5 0.8953
983 DQA 0.8952
984 N4B 0.8951
985 LEU 0.8951
986 O7U 0.8951
987 MD0 0.8950
988 1XN 0.8950
989 2PC 0.8950
990 2KT 0.8949
991 0F9 0.8949
992 F5B 0.8948
993 MAJ 0.8947
994 MAK 0.8947
995 OGA 0.8947
996 1U6 0.8947
997 G2H 0.8946
998 GCB 0.8946
999 6VD 0.8944
1000 13P 0.8943
1001 LER 0.8941
1002 0TR 0.8941
1003 NDH 0.8941
1004 6MH 0.8939
1005 FK8 0.8939
1006 FA3 0.8938
1007 HDA 0.8938
1008 CIZ 0.8938
1009 3ZQ 0.8936
1010 MEW 0.8935
1011 DNF 0.8935
1012 MSN 0.8934
1013 SKA 0.8931
1014 3CE 0.8930
1015 12M 0.8930
1016 3PY 0.8930
1017 N2Z 0.8929
1018 5AC 0.8929
1019 5XB 0.8928
1020 YTX 0.8928
1021 II6 0.8928
1022 HXX 0.8928
1023 PRS 0.8927
1024 L5V 0.8926
1025 J9W 0.8925
1026 MZB 0.8925
1027 BEA 0.8924
1028 QX4 0.8924
1029 34V 0.8922
1030 M6N 0.8921
1031 7ME 0.8921
1032 2GS 0.8921
1033 260 0.8921
1034 SIN 0.8920
1035 FUM 0.8920
1036 2C9 0.8920
1037 6ME 0.8920
1038 40O 0.8920
1039 2HC 0.8919
1040 FX1 0.8918
1041 M4E 0.8918
1042 MPV 0.8917
1043 LT1 0.8916
1044 HLZ 0.8916
1045 SEP 0.8916
1046 97T 0.8914
1047 2LY 0.8913
1048 C2Y 0.8911
1049 3V4 0.8911
1050 7CZ 0.8909
1051 UNC 0.8909
1052 B62 0.8909
1053 8OZ 0.8909
1054 4NG 0.8909
1055 GUA 0.8908
1056 O2A 0.8906
1057 CTS 0.8906
1058 6HQ 0.8906
1059 TSR 0.8905
1060 EYK 0.8905
1061 FUD 0.8905
1062 4BY 0.8905
1063 MO8 0.8904
1064 4P0 0.8904
1065 IPH 0.8903
1066 2MY 0.8902
1067 JBN 0.8902
1068 3MC 0.8901
1069 280 0.8901
1070 2PG 0.8901
1071 SEJ 0.8901
1072 PHE 0.8899
1073 SD4 0.8899
1074 ESI 0.8899
1075 G3P 0.8899
1076 265 0.8898
1077 KTW 0.8898
1078 2HG 0.8898
1079 NCT 0.8898
1080 TFB 0.8898
1081 3BU 0.8897
1082 K34 0.8897
1083 2CM 0.8894
1084 DTU 0.8894
1085 2IM 0.8894
1086 0FN 0.8892
1087 HAI 0.8892
1088 PSV 0.8892
1089 SMN 0.8891
1090 7WR 0.8891
1091 2CL 0.8890
1092 YPN 0.8885
1093 3FA 0.8885
1094 428 0.8885
1095 M0Q 0.8884
1096 NXA 0.8883
1097 BPW 0.8882
1098 KG7 0.8882
1099 M0W 0.8881
1100 TP5 0.8881
1101 DQU 0.8881
1102 TZC 0.8881
1103 PRI 0.8880
1104 2BX 0.8880
1105 GYP 0.8880
1106 MFU 0.8879
1107 DGN 0.8879
1108 44V 0.8879
1109 DAL DAL 0.8878
1110 X0W 0.8878
1111 DUB 0.8877
1112 NVI 0.8877
1113 GMN 0.8875
1114 EXO 0.8874
1115 2AS 0.8874
1116 AJ2 0.8873
1117 GLY CYS 0.8873
1118 GRO 0.8871
1119 8NB 0.8871
1120 YTB 0.8871
1121 DGY 0.8870
1122 UNJ 0.8870
1123 AJV 0.8869
1124 SF6 0.8869
1125 GTL 0.8869
1126 THR 0.8869
1127 CAQ 0.8869
1128 9KH 0.8869
1129 278 0.8868
1130 GOX 0.8868
1131 52C 0.8866
1132 B85 0.8865
1133 GLY PRO 0.8865
1134 A13 0.8864
1135 PEP 0.8864
1136 ONR 0.8863
1137 APZ 0.8863
1138 PYC 0.8859
1139 GXE 0.8858
1140 2TQ 0.8858
1141 MUA 0.8857
1142 FLM 0.8856
1143 FFP 0.8855
1144 94N 0.8854
1145 44W 0.8854
1146 M1H 0.8853
1147 5ZE 0.8852
1148 HJP 0.8852
1149 VAL 0.8851
1150 OXE 0.8848
1151 13X 0.8847
1152 FOA 0.8846
1153 NGO 0.8846
1154 2ZV 0.8845
1155 HIU 0.8845
1156 A2Q 0.8845
1157 SC2 0.8844
1158 93B 0.8843
1159 SRO 0.8842
1160 8U3 0.8841
1161 DRL 0.8841
1162 S24 0.8840
1163 PRF 0.8840
1164 HVQ 0.8838
1165 XHP 0.8837
1166 6X8 0.8837
1167 3MH 0.8837
1168 MMA 0.8837
1169 XDE 0.8836
1170 EQT 0.8836
1171 3PG 0.8836
1172 CXL 0.8836
1173 IHG 0.8836
1174 DCY 0.8835
1175 MLE 0.8834
1176 TFU 0.8833
1177 DS0 0.8832
1178 B40 0.8831
1179 X09 0.8829
1180 INS 0.8829
1181 HTS 0.8828
1182 HC4 0.8828
1183 2FT 0.8827
1184 INE 0.8827
1185 C21 0.8826
1186 OTW 0.8823
1187 C2N 0.8823
1188 FP2 0.8823
1189 36E 0.8823
1190 6JN 0.8823
1191 293 0.8822
1192 8NX 0.8820
1193 TM4 0.8820
1194 23J 0.8818
1195 3ZB 0.8818
1196 SXS 0.8818
1197 AOS 0.8817
1198 273 0.8817
1199 CMS 0.8817
1200 LSA 0.8817
1201 2IT 0.8816
1202 DGL 0.8816
1203 1L5 0.8816
1204 4MU 0.8814
1205 TMZ 0.8814
1206 PDC 0.8814
1207 G3H 0.8812
1208 4AV 0.8812
1209 MLI 0.8812
1210 VK3 0.8812
1211 8LG 0.8811
1212 GGL 0.8811
1213 IPZ 0.8810
1214 R20 0.8809
1215 QSB 0.8809
1216 MZ0 0.8809
1217 2CH 0.8808
1218 CPZ 0.8808
1219 L89 0.8807
1220 SMV 0.8807
1221 MSE 0.8806
1222 DHQ 0.8805
1223 9CA 0.8804
1224 1AN 0.8803
1225 TTO 0.8803
1226 8W9 0.8803
1227 XSP 0.8802
1228 XXP 0.8802
1229 8CL 0.8801
1230 3AY 0.8801
1231 TAG 0.8801
1232 EXD 0.8801
1233 2ZX 0.8800
1234 FHN 0.8800
1235 HHH 0.8800
1236 92Z 0.8799
1237 CYH 0.8799
1238 X05 0.8798
1239 DYT 0.8798
1240 PIH 0.8797
1241 2F6 0.8797
1242 4BL 0.8797
1243 JZ0 0.8796
1244 AX2 0.8796
1245 2AF 0.8795
1246 DZX 0.8795
1247 SNO 0.8794
1248 ABA 0.8794
1249 463 0.8794
1250 0FO 0.8793
1251 Q02 0.8793
1252 NGT 0.8793
1253 NGW 0.8793
1254 RNO 0.8792
1255 9ON 0.8791
1256 1SA 0.8791
1257 2MN 0.8791
1258 E60 0.8790
1259 76X 0.8790
1260 SSB 0.8790
1261 MT0 0.8788
1262 BVG 0.8788
1263 HGW 0.8787
1264 MSR 0.8787
1265 3WA 0.8787
1266 DTT 0.8786
1267 1IT 0.8785
1268 SNE 0.8785
1269 TEP 0.8784
1270 93Q 0.8783
1271 F12 0.8783
1272 HHN 0.8781
1273 BVC 0.8779
1274 MEV 0.8778
1275 KMH 0.8777
1276 DMG 0.8775
1277 GCO 0.8773
1278 CXP 0.8772
1279 DLY 0.8771
1280 KIB 0.8771
1281 QPR 0.8768
1282 15E 0.8768
1283 9TY 0.8768
1284 LQ2 0.8767
1285 4NB 0.8766
1286 LYS 0.8765
1287 M4S 0.8761
1288 OW7 0.8761
1289 R67 0.8760
1290 WOT 0.8760
1291 TMT 0.8760
1292 PQ0 0.8760
1293 BR8 0.8758
1294 ISE 0.8757
1295 0V5 0.8756
1296 4SD 0.8756
1297 4VY 0.8756
1298 ERH 0.8753
1299 MBN 0.8753
1300 NAG 0.8753
1301 I3E 0.8752
1302 FBU 0.8750
1303 495 0.8749
1304 39A 0.8748
1305 4XX 0.8748
1306 PEQ 0.8747
1307 H33 0.8746
1308 0OC 0.8745
1309 2AK 0.8744
1310 L14 0.8742
1311 FLA 0.8742
1312 WDL 0.8741
1313 N7I 0.8741
1314 SME 0.8740
1315 NDM 0.8740
1316 CGB 0.8740
1317 N3W 0.8738
1318 57O 0.8738
1319 HZQ 0.8736
1320 B0D 0.8736
1321 1AL 0.8736
1322 MLA 0.8736
1323 GLY GLY 0.8735
1324 1CO 0.8735
1325 PD2 0.8735
1326 AES 0.8735
1327 JBQ 0.8734
1328 RUY 0.8734
1329 329 0.8734
1330 37T 0.8733
1331 SYA 0.8733
1332 SDD 0.8731
1333 CXH 0.8730
1334 938 0.8729
1335 K7M 0.8729
1336 4RU 0.8728
1337 QX2 0.8728
1338 209 0.8727
1339 Z5P 0.8727
1340 GJP 0.8726
1341 0FK 0.8726
1342 ADK 0.8725
1343 3MA 0.8725
1344 4TU 0.8722
1345 CDV 0.8722
1346 P7Y 0.8721
1347 SER 0.8721
1348 MJ2 0.8720
1349 1DH 0.8717
1350 8XL 0.8717
1351 GLO 0.8716
1352 N8P 0.8715
1353 JAB 0.8714
1354 MVN 0.8714
1355 9PY 0.8714
1356 A7H 0.8713
1357 PSJ 0.8712
1358 KDF 0.8711
1359 SKG 0.8710
1360 6TZ 0.8710
1361 GF4 0.8708
1362 IZC 0.8706
1363 7ZE 0.8705
1364 4AP 0.8704
1365 TCA 0.8704
1366 MQB 0.8703
1367 PPY 0.8701
1368 5WY 0.8701
1369 QWW 0.8700
1370 HVK 0.8700
1371 24T 0.8699
1372 A7N 0.8699
1373 HCI 0.8699
1374 CEJ 0.8699
1375 DA4 0.8696
1376 2EZ 0.8696
1377 8EW 0.8694
1378 TCZ 0.8692
1379 TT4 0.8692
1380 CIY 0.8691
1381 1DQ 0.8691
1382 EVF 0.8690
1383 P2D 0.8690
1384 BNT 0.8689
1385 PMF 0.8686
1386 UFO 0.8686
1387 8K2 0.8683
1388 152 0.8683
1389 SFU 0.8683
1390 PH2 0.8682
1391 HHR 0.8682
1392 L60 0.8682
1393 PYQ 0.8681
1394 RPQ 0.8679
1395 CIT 0.8679
1396 8G0 0.8678
1397 8HC 0.8678
1398 FBT 0.8678
1399 LLQ 0.8677
1400 HDL 0.8676
1401 NVU 0.8676
1402 3AP 0.8675
1403 6OT 0.8674
1404 2AP 0.8674
1405 ZZZ 0.8674
1406 2CZ 0.8674
1407 T2C 0.8674
1408 27B 0.8673
1409 DEW 0.8669
1410 32X 0.8668
1411 FPK 0.8668
1412 DSN 0.8667
1413 XIZ 0.8667
1414 PBE 0.8667
1415 5AN 0.8665
1416 2O6 0.8664
1417 JG8 0.8663
1418 TMH 0.8663
1419 HA7 0.8662
1420 GWM 0.8661
1421 V1L 0.8661
1422 K32 0.8661
1423 PG3 0.8660
1424 6R8 0.8658
1425 PGA 0.8657
1426 YAN 0.8656
1427 C5J 0.8655
1428 4JC 0.8653
1429 AAN 0.8653
1430 36Y 0.8653
1431 ABU 0.8653
1432 APG 0.8650
1433 61M 0.8649
1434 6KT 0.8649
1435 2ZQ 0.8648
1436 KIA 0.8647
1437 FSW 0.8646
1438 9KT 0.8643
1439 FDR 0.8641
1440 AAE 0.8641
1441 GV9 0.8639
1442 HRZ 0.8638
1443 IQ0 0.8638
1444 MA3 0.8634
1445 EGR 0.8633
1446 GVG 0.8631
1447 IWT 0.8627
1448 NQ 0.8626
1449 M1Z 0.8626
1450 LGA 0.8625
1451 N7P 0.8625
1452 ACH 0.8625
1453 LEA 0.8625
1454 RXA 0.8622
1455 SNU 0.8620
1456 2FQ 0.8619
1457 41K 0.8617
1458 GM7 0.8615
1459 9PO 0.8614
1460 CFF 0.8614
1461 3DY 0.8612
1462 BHH 0.8610
1463 P84 0.8609
1464 YQA 0.8607
1465 PAH 0.8603
1466 6KX 0.8599
1467 DNC 0.8599
1468 GG6 0.8595
1469 XQI 0.8591
1470 A5E 0.8585
1471 NSG 0.8582
1472 SYG 0.8581
1473 PFL 0.8580
1474 1XA 0.8579
1475 P4B 0.8576
1476 K17 0.8575
1477 289 0.8574
1478 HL4 0.8574
1479 PLU 0.8573
1480 IPM 0.8570
1481 1KP 0.8570
1482 BNL 0.8569
1483 PJW 0.8569
1484 A09 0.8569
1485 K22 0.8557
1486 4A5 0.8556
1487 AY4 0.8555
1488 TYR 0.8555
1489 2KA 0.8551
1490 QAT 0.8548
1491 GJS 0.8539
1492 DCL 0.8539
1493 CFA 0.8535
1494 86L 0.8509
1495 F1A 0.8506
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 6QXD; Ligand: JKB; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 6qxd.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
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