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Receptor
PDB id Resolution Class Description Source Keywords
3NDJ 1.5 Å EC: 2.1.1.- X-RAY STRUCTURE OF A C-3'-METHYLTRANSFERASE IN COMPLEX WITH ADENOSYL-L-HOMOCYSTEINE AND SUGAR PRODUCT MICROMONOSPORA CHALCEA S-ADENOSYL-L-HOMOCYSTEINE KIJANOSE TETRONITROSE TETRADEOXKETO SUGAR MICROMONOSPORA CHALCEA TCAB9 C-3-prime -METHYLTRANSSUGAR METHYLATION TRANSFERASE
Ref.: MOLECULAR ARCHITECTURE OF A C-3'-METHYLTRANSFERASE IN THE BIOSYNTHESIS OF D-TETRONITROSE. BIOCHEMISTRY V. 49 5891 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
JHZ A:418;
Valid;
none;
submit data
543.356 C17 H27 N3 O13 P2 C[C@@...
PO4 A:417;
Invalid;
none;
submit data
94.971 O4 P [O-]P...
SAH A:415;
Valid;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
ZN A:416;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3NDJ 1.5 Å EC: 2.1.1.- X-RAY STRUCTURE OF A C-3'-METHYLTRANSFERASE IN COMPLEX WITH ADENOSYL-L-HOMOCYSTEINE AND SUGAR PRODUCT MICROMONOSPORA CHALCEA S-ADENOSYL-L-HOMOCYSTEINE KIJANOSE TETRONITROSE TETRADEOXKETO SUGAR MICROMONOSPORA CHALCEA TCAB9 C-3-prime -METHYLTRANSSUGAR METHYLATION TRANSFERASE
Ref.: MOLECULAR ARCHITECTURE OF A C-3'-METHYLTRANSFERASE IN THE BIOSYNTHESIS OF D-TETRONITROSE. BIOCHEMISTRY V. 49 5891 2010
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 4E33 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4E2W - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
3 4E2Z - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
4 4E30 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 4E2X - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 4E32 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 4E2Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 4E31 - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
9 3NDI - SAM C15 H22 N6 O5 S C[S@@+](CC....
10 3NDJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (13)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 4E33 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 4E2W - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
3 4E2Z - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
4 4E30 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 4E2X - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 4E32 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 4E2Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 4E31 - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
9 3NDI - SAM C15 H22 N6 O5 S C[S@@+](CC....
10 3NDJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
11 5T6B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 5T67 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
13 5T64 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 4RVD - SAM C15 H22 N6 O5 S C[S@@+](CC....
2 4RVG - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 4RV9 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 4RVH - 3YN C16 H24 N2 O14 P2 C[C@@H]1C(....
5 4E33 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 4E2W - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
7 4E2Z - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
8 4E30 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
9 4E2X - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 4E32 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
11 4E2Y - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 4E31 - JHZ C17 H27 N3 O13 P2 C[C@@H]1C(....
13 3NDI - SAM C15 H22 N6 O5 S C[S@@+](CC....
14 3NDJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
15 5T6B - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 5T67 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
17 5T64 - TMP C10 H15 N2 O8 P CC1=CN(C(=....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: JHZ; Similar ligands found: 57
No: Ligand ECFP6 Tc MDL keys Tc
1 JHZ 1 1
2 AKM 0.74 0.974684
3 DWN 0.72449 0.974026
4 3YN 0.707071 0.948052
5 0N2 0.666667 0.961538
6 TTP 0.638298 0.884615
7 3R2 0.637255 0.935897
8 TRH 0.637255 0.923077
9 18T 0.637255 0.923077
10 1JB 0.637255 0.923077
11 T46 0.634615 0.923077
12 DAU 0.631068 0.898734
13 TYD 0.630435 0.884615
14 T3F 0.625 0.948718
15 T3Q 0.625 0.948718
16 0FX 0.613208 0.948718
17 TDX 0.605769 0.910256
18 MMF 0.598131 0.924051
19 QDM 0.587156 0.9125
20 TLO 0.582524 0.886076
21 FNF 0.581818 0.935897
22 1YF 0.581818 0.935897
23 4TG 0.576577 0.935897
24 TMP 0.576087 0.871795
25 FUH 0.542373 0.948718
26 QUH 0.542373 0.948718
27 DT DT DT 0.495413 0.884615
28 DT DT PST 0.491228 0.841463
29 TBD 0.490196 0.851852
30 T5A 0.488 0.837209
31 7SG 0.481481 0.858824
32 TQP 0.481481 0.858824
33 DT DT DT DT DT 0.473684 0.886076
34 T5K 0.467153 0.848837
35 T4K 0.467153 0.848837
36 ATY 0.457944 0.910256
37 LLT 0.456522 0.794872
38 THM 0.456522 0.794872
39 AZD 0.449541 0.831325
40 0DN 0.446809 0.759494
41 UFP 0.44 0.804878
42 TPE 0.435897 0.911392
43 NYM 0.431373 0.897436
44 DT ME6 DT 0.429688 0.841463
45 THP 0.427184 0.858974
46 T3P 0.424242 0.835443
47 BRU 0.421569 0.804878
48 5HU 0.421569 0.860759
49 4TA 0.421053 0.804598
50 ATM 0.420561 0.819277
51 5IU 0.417476 0.804878
52 FDM 0.417476 0.817073
53 ABT 0.413793 0.811765
54 TXS 0.411765 0.743902
55 D3T 0.407407 0.860759
56 DUT 0.407407 0.846154
57 T3S 0.403846 0.765432
Ligand no: 2; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3NDJ; Ligand: SAH; Similar sites found with APoc: 373
This union binding pocket(no: 1) in the query (biounit: 3ndj.bio1) has 47 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL GLC NBU None
2 2BOS GLA GAL GLC None
3 2UVF AD0 1.20192
4 4PIO AVI 1.23839
5 4PIO SAH 1.23839
6 5H81 NAP 1.28535
7 1F8G NAD 1.30208
8 1L7E NAI 1.30208
9 3MAG SAH 1.30293
10 3MCT SAH 1.3468
11 1U2Z SAH 1.44231
12 1X87 NAD 1.44231
13 5ERG SAM 1.44231
14 3OJO NAD 1.44231
15 5G3U FDA 1.44231
16 1SC6 NAD 1.48515
17 4DMG SAM 1.52672
18 2Q0L NAP 1.60772
19 5XNC MTA 1.61725
20 1HYH NAD 1.61812
21 3GWZ SAH 1.62602
22 3GXO SAH 1.62602
23 4Y9D NAI 1.63934
24 1V59 NAD 1.68269
25 4YAC NAI 1.6835
26 3GMB FAD 1.68675
27 3VSE SAH 1.75879
28 2HJR APR 1.82927
29 3JWH SAH 1.84332
30 2EJU SAH 1.85185
31 5F8F SFG 1.85676
32 1A5Z NAD 1.88088
33 1UP7 NAD 1.92308
34 4X8D AVI 1.92308
35 5VN0 FAD 1.92308
36 4JK3 NAD 1.9305
37 5YF1 SFG 1.9337
38 5YF1 8V0 1.9337
39 1ZGA SAH 1.96078
40 6AA8 NAD 1.98676
41 1X14 NAD 1.99501
42 5MB4 NAG 1.99501
43 2AOT SAH 2.05479
44 1JQD SAH 2.05479
45 1JQD HSM 2.05479
46 1CER NAD 2.1148
47 1QH9 LAC 2.15517
48 5ZXD ATP 2.16346
49 3S1S SAH 2.16346
50 3TPV ADE 2.16346
51 3S5W FAD 2.16346
52 1NW5 SAM 2.19436
53 3AB1 FAD 2.22222
54 6C4N NAP 2.22717
55 5D4V SAH 2.23881
56 1BW9 NAD 2.24719
57 1C1X NAD 2.25352
58 2PFY PCA 2.32558
59 5U19 SAH 2.34604
60 5U19 827 2.34604
61 5BSZ SAH 2.4
62 4KOA NDP 2.4024
63 6BQ6 TER 2.41692
64 1NVT NAP 2.43902
65 3TKY SAH 2.44565
66 1R0X ATP 2.44755
67 1LTH NAD 2.50784
68 5Z20 NAI 2.6087
69 1ZOS MTM 2.6087
70 2AG8 NAP 2.6616
71 3L9W AMP 2.66344
72 1DSS NAD 2.7027
73 2GCG NDP 2.72727
74 4E5N NAD 2.72727
75 5GWX SAR 2.8169
76 5GWX SAM 2.8169
77 5ICE SAH 2.84091
78 5E9W SAH 2.88462
79 5E8J SAH 2.88462
80 5L2R MLA 2.88462
81 1DJN ADP 2.88462
82 4OM8 NAD 2.91262
83 2CBZ ATP 2.95359
84 1RM4 NDP 2.96736
85 5JE8 NAD 2.98013
86 3FZG SAM 3
87 2Q28 ADP 3.01418
88 5Y8L NAD 3.05085
89 3W9F I3P 3.07692
90 5ZJ5 NAI 3.08642
91 5N5D SAM 3.09735
92 3KLJ FAD 3.11688
93 4KRG SAH 3.125
94 2IZ1 ATR 3.125
95 6B3A SAM 3.125
96 5JJR SAH 3.125
97 1A4R GNH 3.14136
98 6AYU MLI 3.17003
99 3TKA SAM 3.17003
100 1XDS SAM 3.20856
101 1QZZ SAM 3.20856
102 5AHO TLA 3.27381
103 1Z82 G3P 3.28358
104 1Z82 G3H 3.28358
105 1V6A TRE 3.31325
106 3Q3C NAD 3.34448
107 2HNK SAH 3.34728
108 2HIM ASN 3.35196
109 2CDU ADP 3.36538
110 1MV8 NAD 3.36538
111 1MUU NAD 3.36538
112 1O0S NAI 3.36538
113 6F7L FAD 3.36538
114 2CDU FAD 3.36538
115 5MGZ SAH 3.38983
116 4NEC SAH 3.40909
117 1WP4 NDP 3.46021
118 1G60 SAM 3.46154
119 4OBW SAM 3.50195
120 4LWP SAH 3.53261
121 1RJW ETF 3.53982
122 1PSC EBP 3.56164
123 1P31 EPU 3.57895
124 1P3D UMA 3.57895
125 3HVJ 705 3.61991
126 3GEG NAD 3.64372
127 5GM1 SAH 3.7037
128 2VT3 ATP 3.72093
129 2PT9 S4M 3.73832
130 2A92 NAI 3.73832
131 2PT9 2MH 3.73832
132 3B1F NAD 3.7931
133 4UP3 NDP 3.82166
134 1JG3 ADN 3.82979
135 1KYZ SAH 3.83562
136 5W7K SAH 3.84615
137 3BGD SAH 3.84615
138 3BGD PM6 3.84615
139 2UYQ SAM 3.87097
140 2PWY SAH 3.87597
141 2BZG SAH 3.87931
142 1G6H ADP 3.89105
143 4O4Z N2O 3.8961
144 5X62 SAH 3.94089
145 1Z0A GDP 4.02299
146 1Z3C SA8 4.02685
147 5JE0 SAH 4.04858
148 5JE0 AZ8 4.04858
149 1G55 SAH 4.08163
150 1OBB NAD 4.08654
151 4U00 ADP 4.09836
152 4BLW SAH 4.15225
153 4RDH AMP 4.16667
154 4RDI ATP 4.16667
155 5MW4 5JU 4.19162
156 1PL6 NAD 4.21348
157 3VYW SAM 4.22078
158 2I7C AAT 4.24028
159 3GCZ SAM 4.25532
160 4V3I ASP LEU THR ARG PRO 4.28016
161 5SXS NIZ 4.32692
162 1XTP SAI 4.33071
163 4D79 ATP 4.34783
164 1TE2 PGA 4.42478
165 1I1N SAH 4.42478
166 6ECW SAH 4.44444
167 5THY SAH 4.44444
168 5THZ SAH 4.44444
169 1BXG NAD 4.49438
170 4AZW SAM 4.56731
171 5W7R SAH 4.56731
172 5GSN NAP 4.56731
173 5GSN FAD 4.56731
174 5YJF 8WO 4.57746
175 5YJF SAH 4.57746
176 3DXY SAM 4.58716
177 2RBK VN4 4.5977
178 2DFV NAD 4.61095
179 1F3L SAH 4.6729
180 6C5B SAH 4.69208
181 1KYQ NAD 4.74453
182 3A27 SAM 4.77941
183 4URG C2E 4.79042
184 3ICT ADP 4.80769
185 3PT9 SAH 4.80769
186 3ICS ADP 4.80769
187 1PJS NAD 4.80769
188 3T7S SAM 4.85075
189 2QQF A1R 4.87013
190 2OD9 A1R NCA 4.87013
191 1O94 ADP 4.92424
192 1NM5 NAD 4.92611
193 2A14 SAH 4.94297
194 6ECT SAM 4.98442
195 1I9G SAM 5
196 2D2I NAP 5
197 2F1K NAP 5.01792
198 3FPF MTA 5.03356
199 3FPF TNA 5.03356
200 2AF6 FAD 5.03876
201 2NVK NAP 5.04808
202 4DCM SAM 5.06667
203 6GKV SAH 5.12821
204 2A5J GDP 5.2356
205 4B4U NAP 5.28053
206 2VDV SAM 5.28455
207 5DNK SAH 5.28846
208 4A6D SAM 5.38244
209 3KB6 NAD 5.38922
210 5KOK SAH 5.52885
211 1LVL NAD 5.52885
212 5KOK R9T 5.52885
213 5X7Q GLC GLC GLC 5.52885
214 5KOK S9T 5.52885
215 2IVD FAD 5.52885
216 5LOG SAH 5.5794
217 3B20 NAD 5.60472
218 1FP1 SAH 5.64516
219 1ZEI CRS 5.66038
220 3H5N ATP 5.66572
221 5XLX SAH 5.67376
222 5HJM MTA 5.68182
223 3LCV SAM 5.69395
224 1LSS NAD 5.71429
225 2ZIF SAM 5.72391
226 2OOR NAD 5.74713
227 5E72 SAM 5.78035
228 4D3F NAP 5.80645
229 3N8K D1X 5.81395
230 5FUB SAH 5.93472
231 6CEP NAD 5.98802
232 5FA5 MTA 5.99455
233 1X7D NAD 6
234 6ECU SAH 6.01266
235 1QAN SAH 6.14754
236 2FKA BEF 6.20155
237 2CZL TLA 6.25
238 2BRY FAD 6.25
239 4GQB 0XU 6.39535
240 4TXI FAD 6.49038
241 3QOX SAH 6.57277
242 2CVZ NDP 6.57439
243 2O07 MTA 6.57895
244 2O07 SPD 6.57895
245 4RL4 PPV 6.60377
246 3OA2 NAD 6.60377
247 1J49 NAD 6.60661
248 1P77 ATR 6.61765
249 2DT5 NAD 6.63507
250 2O66 FLC 6.66667
251 5YJI 8WO 6.69014
252 5YJI SAH 6.69014
253 3BXO SAM 6.69456
254 1J5P NAD 6.71937
255 4KIB SAH 6.72269
256 4IF4 BEF 6.73077
257 3GJ3 GDP 6.78733
258 1FP2 SAH 6.81818
259 5KVA SAM 6.83453
260 3H8V ATP 6.84932
261 3I7S PYR 6.84932
262 3U31 NAD 6.89655
263 3KO0 TFP 6.93069
264 5L95 AMP 7.16846
265 5FWA J7C 7.21154
266 2P41 SAH 7.21311
267 1OH2 SUC 7.26392
268 1KPG SAH 7.31707
269 1KPH SAH 7.31707
270 3G2O SAM 7.35786
271 5FTW SAH 7.42188
272 4XB2 NDP 7.46269
273 4POO SAM 7.5
274 3GJ8 GDP 7.6087
275 1XCL SAH 7.65957
276 2JHP SAH 7.69231
277 1Y8Q ATP 7.69231
278 5MQ6 NDP 7.69231
279 3GFB NAD 7.71429
280 3LST SAH 7.75862
281 3OU2 SAH 7.79817
282 3WV8 ATP 7.79817
283 3W6X HZP 7.86026
284 3EVG SAH 8
285 2YVJ NAI 8.25688
286 1U3R 338 8.29876
287 3OLL EST 8.33333
288 5LD5 NAD 8.37989
289 2P0D I3P 8.52713
290 3QV1 NAD 8.53659
291 6DUB SAH 8.55856
292 5FA8 SAM 8.69565
293 3MQ2 SAH 8.7156
294 4PNE SAH 8.9404
295 3A25 SAM 8.9701
296 6C8R SAH 8.97098
297 1P1C SAH 9.04523
298 3HQP FDP 9.13461
299 2DPM SAM 9.15493
300 6B92 SAH 9.18367
301 3ZZQ TRP 9.23077
302 2O1C PPV 9.33333
303 3IHG FAD 9.375
304 2XVM SAH 9.54774
305 5ULP KB1 9.70149
306 1JQ3 AAT 9.7973
307 2GV8 FAD 9.85577
308 2GVC FAD 9.85577
309 5OFW 9TW 9.86547
310 5OJL TXP 10.0671
311 1VQW FAD 10.0962
312 1L3I SAH 10.4167
313 4II2 ATP 10.4294
314 2RGO FAD 10.5769
315 2G5C NAD 10.6762
316 2ZFU SAH 10.6977
317 2PXX SAH 10.6977
318 6GFK SAH 10.757
319 5E1M PRO PRO LYS ARG ILE ALA 10.7884
320 5E1M SAH 10.7884
321 5MPT SAH 10.8696
322 2JBM SRT 11.0368
323 1BC5 SAH 11.1524
324 2J5V RGP 11.1717
325 1OMO NAD 11.1801
326 3GJ7 GDP 11.2245
327 5BW4 SAM 11.236
328 5N53 8NB 11.2821
329 4KRI SAH 11.2981
330 5WP4 SAH 11.2981
331 5Z21 NAI 11.4525
332 5JGL SAM 12.1107
333 3Q87 SAM 12.3529
334 5W7M SAH 12.5
335 2HK9 ATR 12.7273
336 2HK9 NAP 12.7273
337 2BZ1 TAU 12.7551
338 2HMT NAI 13.1944
339 4ZGS NAD 13.4715
340 1EZ4 NAD 13.8365
341 5UFN SAH 13.8655
342 4AIA ADK 14.3617
343 3IWD M2T 14.5161
344 3PFG TLO 14.8289
345 3PFG SAM 14.8289
346 4R6W SAH 15.1163
347 4R6W PC 15.1163
348 2V7Q ADP 15.1515
349 4CQM NAP 15.1639
350 1DL5 SAH 15.4574
351 3H2B SAH 15.7635
352 2YX1 SFG 15.7738
353 2WPB ZZI 15.7895
354 6F5Z SAH 16.4502
355 5YEC ATP 16.8067
356 5T9E NAP 16.9742
357 3MB5 SAM 17.2549
358 1R18 SAH 17.6211
359 1VE3 SAM 18.5022
360 3OF1 CMP 18.6992
361 5DWQ SFG 19.7708
362 5DX8 SFG 19.7708
363 5DX1 SFG 19.7708
364 5DXA SFG 19.7708
365 5DX0 SFG 19.7708
366 6ARJ SAH 19.7708
367 6ARJ BW4 19.7708
368 3P2E SAH 20.4444
369 1TPY SAH 21.9512
370 1L1E SAH 22.9965
371 5ZZ6 ADP 24.5192
372 5ZZ6 NAD 24.5192
373 4YMH SAH 30
Pocket No.: 2; Query (leader) PDB : 3NDJ; Ligand: JHZ; Similar sites found with APoc: 373
This union binding pocket(no: 2) in the query (biounit: 3ndj.bio1) has 47 residues
No: Leader PDB Ligand Sequence Similarity
1 2BOS GLA GAL GLC NBU None
2 2BOS GLA GAL GLC None
3 2UVF AD0 1.20192
4 4PIO AVI 1.23839
5 4PIO SAH 1.23839
6 5H81 NAP 1.28535
7 1F8G NAD 1.30208
8 1L7E NAI 1.30208
9 3MAG SAH 1.30293
10 3MCT SAH 1.3468
11 1U2Z SAH 1.44231
12 1X87 NAD 1.44231
13 5ERG SAM 1.44231
14 3OJO NAD 1.44231
15 5G3U FDA 1.44231
16 1SC6 NAD 1.48515
17 4DMG SAM 1.52672
18 2Q0L NAP 1.60772
19 5XNC MTA 1.61725
20 1HYH NAD 1.61812
21 3GWZ SAH 1.62602
22 3GXO SAH 1.62602
23 4Y9D NAI 1.63934
24 1V59 NAD 1.68269
25 4YAC NAI 1.6835
26 3GMB FAD 1.68675
27 3VSE SAH 1.75879
28 2HJR APR 1.82927
29 3JWH SAH 1.84332
30 2EJU SAH 1.85185
31 5F8F SFG 1.85676
32 1A5Z NAD 1.88088
33 1UP7 NAD 1.92308
34 4X8D AVI 1.92308
35 5VN0 FAD 1.92308
36 4JK3 NAD 1.9305
37 5YF1 SFG 1.9337
38 5YF1 8V0 1.9337
39 1ZGA SAH 1.96078
40 6AA8 NAD 1.98676
41 1X14 NAD 1.99501
42 5MB4 NAG 1.99501
43 2AOT SAH 2.05479
44 1JQD SAH 2.05479
45 1JQD HSM 2.05479
46 1CER NAD 2.1148
47 1QH9 LAC 2.15517
48 5ZXD ATP 2.16346
49 3S1S SAH 2.16346
50 3TPV ADE 2.16346
51 3S5W FAD 2.16346
52 1NW5 SAM 2.19436
53 3AB1 FAD 2.22222
54 6C4N NAP 2.22717
55 5D4V SAH 2.23881
56 1BW9 NAD 2.24719
57 1C1X NAD 2.25352
58 2PFY PCA 2.32558
59 5U19 SAH 2.34604
60 5U19 827 2.34604
61 5BSZ SAH 2.4
62 4KOA NDP 2.4024
63 6BQ6 TER 2.41692
64 1NVT NAP 2.43902
65 3TKY SAH 2.44565
66 1R0X ATP 2.44755
67 1LTH NAD 2.50784
68 5Z20 NAI 2.6087
69 1ZOS MTM 2.6087
70 2AG8 NAP 2.6616
71 3L9W AMP 2.66344
72 1DSS NAD 2.7027
73 2GCG NDP 2.72727
74 4E5N NAD 2.72727
75 5GWX SAR 2.8169
76 5GWX SAM 2.8169
77 5ICE SAH 2.84091
78 5E9W SAH 2.88462
79 5E8J SAH 2.88462
80 5L2R MLA 2.88462
81 1DJN ADP 2.88462
82 4OM8 NAD 2.91262
83 2CBZ ATP 2.95359
84 1RM4 NDP 2.96736
85 5JE8 NAD 2.98013
86 3FZG SAM 3
87 2Q28 ADP 3.01418
88 5Y8L NAD 3.05085
89 3W9F I3P 3.07692
90 5ZJ5 NAI 3.08642
91 5N5D SAM 3.09735
92 3KLJ FAD 3.11688
93 4KRG SAH 3.125
94 2IZ1 ATR 3.125
95 6B3A SAM 3.125
96 5JJR SAH 3.125
97 1A4R GNH 3.14136
98 6AYU MLI 3.17003
99 3TKA SAM 3.17003
100 1XDS SAM 3.20856
101 1QZZ SAM 3.20856
102 5AHO TLA 3.27381
103 1Z82 G3P 3.28358
104 1Z82 G3H 3.28358
105 1V6A TRE 3.31325
106 3Q3C NAD 3.34448
107 2HNK SAH 3.34728
108 2HIM ASN 3.35196
109 2CDU ADP 3.36538
110 1MV8 NAD 3.36538
111 1MUU NAD 3.36538
112 1O0S NAI 3.36538
113 6F7L FAD 3.36538
114 2CDU FAD 3.36538
115 5MGZ SAH 3.38983
116 4NEC SAH 3.40909
117 1WP4 NDP 3.46021
118 1G60 SAM 3.46154
119 4OBW SAM 3.50195
120 4LWP SAH 3.53261
121 1RJW ETF 3.53982
122 1PSC EBP 3.56164
123 1P31 EPU 3.57895
124 1P3D UMA 3.57895
125 3HVJ 705 3.61991
126 3GEG NAD 3.64372
127 5GM1 SAH 3.7037
128 2VT3 ATP 3.72093
129 2PT9 S4M 3.73832
130 2A92 NAI 3.73832
131 2PT9 2MH 3.73832
132 3B1F NAD 3.7931
133 4UP3 NDP 3.82166
134 1JG3 ADN 3.82979
135 1KYZ SAH 3.83562
136 5W7K SAH 3.84615
137 3BGD SAH 3.84615
138 3BGD PM6 3.84615
139 2UYQ SAM 3.87097
140 2PWY SAH 3.87597
141 2BZG SAH 3.87931
142 1G6H ADP 3.89105
143 4O4Z N2O 3.8961
144 5X62 SAH 3.94089
145 1Z0A GDP 4.02299
146 1Z3C SA8 4.02685
147 5JE0 SAH 4.04858
148 5JE0 AZ8 4.04858
149 1G55 SAH 4.08163
150 1OBB NAD 4.08654
151 4U00 ADP 4.09836
152 4BLW SAH 4.15225
153 4RDH AMP 4.16667
154 4RDI ATP 4.16667
155 5MW4 5JU 4.19162
156 1PL6 NAD 4.21348
157 3VYW SAM 4.22078
158 2I7C AAT 4.24028
159 3GCZ SAM 4.25532
160 4V3I ASP LEU THR ARG PRO 4.28016
161 5SXS NIZ 4.32692
162 1XTP SAI 4.33071
163 4D79 ATP 4.34783
164 1TE2 PGA 4.42478
165 1I1N SAH 4.42478
166 6ECW SAH 4.44444
167 5THY SAH 4.44444
168 5THZ SAH 4.44444
169 1BXG NAD 4.49438
170 4AZW SAM 4.56731
171 5W7R SAH 4.56731
172 5GSN NAP 4.56731
173 5GSN FAD 4.56731
174 5YJF 8WO 4.57746
175 5YJF SAH 4.57746
176 3DXY SAM 4.58716
177 2RBK VN4 4.5977
178 2DFV NAD 4.61095
179 1F3L SAH 4.6729
180 6C5B SAH 4.69208
181 1KYQ NAD 4.74453
182 3A27 SAM 4.77941
183 4URG C2E 4.79042
184 3ICT ADP 4.80769
185 3PT9 SAH 4.80769
186 3ICS ADP 4.80769
187 1PJS NAD 4.80769
188 3T7S SAM 4.85075
189 2QQF A1R 4.87013
190 2OD9 A1R NCA 4.87013
191 1O94 ADP 4.92424
192 1NM5 NAD 4.92611
193 2A14 SAH 4.94297
194 6ECT SAM 4.98442
195 1I9G SAM 5
196 2D2I NAP 5
197 2F1K NAP 5.01792
198 3FPF MTA 5.03356
199 3FPF TNA 5.03356
200 2AF6 FAD 5.03876
201 2NVK NAP 5.04808
202 4DCM SAM 5.06667
203 6GKV SAH 5.12821
204 2A5J GDP 5.2356
205 4B4U NAP 5.28053
206 2VDV SAM 5.28455
207 5DNK SAH 5.28846
208 4A6D SAM 5.38244
209 3KB6 NAD 5.38922
210 5KOK SAH 5.52885
211 1LVL NAD 5.52885
212 5KOK R9T 5.52885
213 5X7Q GLC GLC GLC 5.52885
214 5KOK S9T 5.52885
215 2IVD FAD 5.52885
216 5LOG SAH 5.5794
217 3B20 NAD 5.60472
218 1FP1 SAH 5.64516
219 1ZEI CRS 5.66038
220 3H5N ATP 5.66572
221 5XLX SAH 5.67376
222 5HJM MTA 5.68182
223 3LCV SAM 5.69395
224 1LSS NAD 5.71429
225 2ZIF SAM 5.72391
226 2OOR NAD 5.74713
227 5E72 SAM 5.78035
228 4D3F NAP 5.80645
229 3N8K D1X 5.81395
230 5FUB SAH 5.93472
231 6CEP NAD 5.98802
232 5FA5 MTA 5.99455
233 1X7D NAD 6
234 6ECU SAH 6.01266
235 1QAN SAH 6.14754
236 2FKA BEF 6.20155
237 2CZL TLA 6.25
238 2BRY FAD 6.25
239 4GQB 0XU 6.39535
240 4TXI FAD 6.49038
241 3QOX SAH 6.57277
242 2CVZ NDP 6.57439
243 2O07 MTA 6.57895
244 2O07 SPD 6.57895
245 4RL4 PPV 6.60377
246 3OA2 NAD 6.60377
247 1J49 NAD 6.60661
248 1P77 ATR 6.61765
249 2DT5 NAD 6.63507
250 2O66 FLC 6.66667
251 5YJI 8WO 6.69014
252 5YJI SAH 6.69014
253 3BXO SAM 6.69456
254 1J5P NAD 6.71937
255 4KIB SAH 6.72269
256 4IF4 BEF 6.73077
257 3GJ3 GDP 6.78733
258 1FP2 SAH 6.81818
259 5KVA SAM 6.83453
260 3H8V ATP 6.84932
261 3I7S PYR 6.84932
262 3U31 NAD 6.89655
263 3KO0 TFP 6.93069
264 5L95 AMP 7.16846
265 5FWA J7C 7.21154
266 2P41 SAH 7.21311
267 1OH2 SUC 7.26392
268 1KPG SAH 7.31707
269 1KPH SAH 7.31707
270 3G2O SAM 7.35786
271 5FTW SAH 7.42188
272 4XB2 NDP 7.46269
273 4POO SAM 7.5
274 3GJ8 GDP 7.6087
275 1XCL SAH 7.65957
276 2JHP SAH 7.69231
277 1Y8Q ATP 7.69231
278 5MQ6 NDP 7.69231
279 3GFB NAD 7.71429
280 3LST SAH 7.75862
281 3OU2 SAH 7.79817
282 3WV8 ATP 7.79817
283 3W6X HZP 7.86026
284 3EVG SAH 8
285 2YVJ NAI 8.25688
286 1U3R 338 8.29876
287 3OLL EST 8.33333
288 5LD5 NAD 8.37989
289 2P0D I3P 8.52713
290 3QV1 NAD 8.53659
291 6DUB SAH 8.55856
292 5FA8 SAM 8.69565
293 3MQ2 SAH 8.7156
294 4PNE SAH 8.9404
295 3A25 SAM 8.9701
296 6C8R SAH 8.97098
297 1P1C SAH 9.04523
298 3HQP FDP 9.13461
299 2DPM SAM 9.15493
300 6B92 SAH 9.18367
301 3ZZQ TRP 9.23077
302 2O1C PPV 9.33333
303 3IHG FAD 9.375
304 2XVM SAH 9.54774
305 5ULP KB1 9.70149
306 1JQ3 AAT 9.7973
307 2GV8 FAD 9.85577
308 2GVC FAD 9.85577
309 5OFW 9TW 9.86547
310 5OJL TXP 10.0671
311 1VQW FAD 10.0962
312 1L3I SAH 10.4167
313 4II2 ATP 10.4294
314 2RGO FAD 10.5769
315 2G5C NAD 10.6762
316 2ZFU SAH 10.6977
317 2PXX SAH 10.6977
318 6GFK SAH 10.757
319 5E1M PRO PRO LYS ARG ILE ALA 10.7884
320 5E1M SAH 10.7884
321 5MPT SAH 10.8696
322 2JBM SRT 11.0368
323 1BC5 SAH 11.1524
324 2J5V RGP 11.1717
325 1OMO NAD 11.1801
326 3GJ7 GDP 11.2245
327 5BW4 SAM 11.236
328 5N53 8NB 11.2821
329 4KRI SAH 11.2981
330 5WP4 SAH 11.2981
331 5Z21 NAI 11.4525
332 5JGL SAM 12.1107
333 3Q87 SAM 12.3529
334 5W7M SAH 12.5
335 2HK9 ATR 12.7273
336 2HK9 NAP 12.7273
337 2BZ1 TAU 12.7551
338 2HMT NAI 13.1944
339 4ZGS NAD 13.4715
340 1EZ4 NAD 13.8365
341 5UFN SAH 13.8655
342 4AIA ADK 14.3617
343 3IWD M2T 14.5161
344 3PFG TLO 14.8289
345 3PFG SAM 14.8289
346 4R6W SAH 15.1163
347 4R6W PC 15.1163
348 2V7Q ADP 15.1515
349 4CQM NAP 15.1639
350 1DL5 SAH 15.4574
351 3H2B SAH 15.7635
352 2YX1 SFG 15.7738
353 2WPB ZZI 15.7895
354 6F5Z SAH 16.4502
355 5YEC ATP 16.8067
356 5T9E NAP 16.9742
357 3MB5 SAM 17.2549
358 1R18 SAH 17.6211
359 1VE3 SAM 18.5022
360 3OF1 CMP 18.6992
361 5DWQ SFG 19.7708
362 5DX8 SFG 19.7708
363 5DX1 SFG 19.7708
364 5DXA SFG 19.7708
365 5DX0 SFG 19.7708
366 6ARJ SAH 19.7708
367 6ARJ BW4 19.7708
368 3P2E SAH 20.4444
369 1TPY SAH 21.9512
370 1L1E SAH 22.9965
371 5ZZ6 ADP 24.5192
372 5ZZ6 NAD 24.5192
373 4YMH SAH 30
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