Receptor
PDB id Resolution Class Description Source Keywords
3NBQ 2.3 Å EC: 2.4.2.3 HUMAN URIDINE PHOSPHORYLASE 1 (HUPP1) WITH 5-FLUOROURACIL HOMO SAPIENS NUCLEOSIDE PHOSPHORYLASE 5-FLUOROURACIL CHEMOTHERAPY TRAN
Ref.: ACTIVE SITE CONFORMATIONAL DYNAMICS IN HUMAN URIDIN PHOSPHORYLASE 1. PLOS ONE V. 5 12741 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
URF A:400;
B:400;
C:400;
D:400;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
130.077 C4 H3 F N2 O2 C1=C(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3EUF 1.9 Å EC: 2.4.2.3 CRYSTAL STRUCTURE OF BAU-BOUND HUMAN URIDINE PHOSPHORYLASE 1 HOMO SAPIENS NUCLEOSIDE PHOSPHORYLASE URIDINE RESCUE 5- BENZYLACYCLOURIDINE ALTERNATIVE SPLICING GLYCOSYLTRANSFERASE TRANSFERASE
Ref.: IMPLICATIONS OF THE STRUCTURE OF HUMAN URIDINE PHOSPHORYLASE 1 ON THE DEVELOPMENT OF NOVEL INHIBITORS FOR IMPROVING THE THERAPEUTIC WINDOW OF FLUOROPYRIMIDINE CHEMOTHERAPY. BMC STRUCT.BIOL. V. 9 14 2009
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 3EUF - BAU C14 H16 N2 O4 c1ccc(cc1)....
2 3NBQ - URF C4 H3 F N2 O2 C1=C(C(=O)....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 277 families.
1 3P0E - BAU C14 H16 N2 O4 c1ccc(cc1)....
2 3P0F - BAU C14 H16 N2 O4 c1ccc(cc1)....
3 3EUF - BAU C14 H16 N2 O4 c1ccc(cc1)....
4 3NBQ - URF C4 H3 F N2 O2 C1=C(C(=O)....
5 3KVY - URA C4 H4 N2 O2 C1=CNC(=O)....
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3P0E - BAU C14 H16 N2 O4 c1ccc(cc1)....
2 3P0F - BAU C14 H16 N2 O4 c1ccc(cc1)....
3 3EUF - BAU C14 H16 N2 O4 c1ccc(cc1)....
4 3NBQ - URF C4 H3 F N2 O2 C1=C(C(=O)....
5 5CYF - FLC C6 H5 O7 C(C(=O)[O-....
6 4TXJ - THM C10 H14 N2 O5 CC1=CN(C(=....
7 4TXM - TDR C5 H6 N2 O2 CC1=CNC(=O....
8 4TXL - URA C4 H4 N2 O2 C1=CNC(=O)....
9 4TXN - URF C4 H3 F N2 O2 C1=C(C(=O)....
10 3KVY - URA C4 H4 N2 O2 C1=CNC(=O)....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: URF; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 URF 1 1
2 WBU 0.466667 0.804348
3 IUR 0.451613 0.952381
4 TDR 0.451613 0.860465
5 5UC 0.451613 0.952381
6 5NU 0.441176 0.649123
7 FYU 0.411765 0.860465
8 HMU 0.4 0.74
Similar Ligands (3D)
Ligand no: 1; Ligand: URF; Similar ligands found: 1168
No: Ligand Similarity coefficient
1 A1U 1.0000
2 ICP 1.0000
3 PYD 1.0000
4 1MC 1.0000
5 275 1.0000
6 2MP 1.0000
7 XYD 1.0000
8 MCT 1.0000
9 34A 1.0000
10 2AC 1.0000
11 MWM 1.0000
12 4ZE 1.0000
13 XBZ 1.0000
14 4HO 1.0000
15 TH0 0.9983
16 XYP 0.9982
17 43M 0.9976
18 4CL 0.9962
19 4JJ 0.9961
20 JZ2 0.9960
21 2YU 0.9952
22 MZG 0.9952
23 4JO 0.9948
24 FPY 0.9947
25 5MH 0.9933
26 LXC 0.9929
27 27Y 0.9911
28 HT4 0.9905
29 BR9 0.9897
30 TM7 0.9892
31 IDH 0.9890
32 40O 0.9877
33 MWJ 0.9877
34 3ZQ 0.9874
35 5JC 0.9870
36 TLD 0.9848
37 RIP 0.9793
38 4JU 0.9787
39 AHR 0.9782
40 URA 0.9779
41 4XR 0.9773
42 DFU 0.9769
43 RCO 0.9768
44 Y8I 0.9764
45 CYT 0.9757
46 LG3 0.9755
47 XYS 0.9754
48 26D 0.9752
49 0MK 0.9746
50 OXE 0.9746
51 EDG 0.9739
52 3CH 0.9739
53 R2B 0.9736
54 CRS 0.9735
55 ABE 0.9728
56 LG5 0.9723
57 284 0.9722
58 KOJ 0.9721
59 JIF 0.9719
60 H3M 0.9716
61 ZZT 0.9713
62 CAQ 0.9713
63 RSF 0.9711
64 HPA 0.9710
65 NSP 0.9707
66 1AB 0.9705
67 GVH 0.9703
68 1PT 0.9702
69 L89 0.9701
70 4JP 0.9699
71 92Z 0.9698
72 0R1 0.9698
73 2AF 0.9697
74 2MH 0.9697
75 1AN 0.9696
76 9DA 0.9695
77 FP2 0.9695
78 24B 0.9695
79 10L 0.9693
80 IND 0.9693
81 JZ0 0.9692
82 MPI 0.9692
83 0TR 0.9690
84 RP7 0.9690
85 8H8 0.9689
86 8LG 0.9688
87 BZI 0.9688
88 BZF 0.9684
89 6MP 0.9683
90 LZ1 0.9682
91 ADE 0.9681
92 DUC 0.9681
93 76X 0.9680
94 BVF 0.9680
95 93Q 0.9678
96 DEN 0.9676
97 NK 0.9674
98 0CT 0.9674
99 OXZ 0.9674
100 BEW 0.9671
101 IFM 0.9671
102 1XX 0.9669
103 HQE 0.9666
104 7WA 0.9662
105 7HP 0.9661
106 938 0.9659
107 8GF 0.9659
108 PLQ 0.9655
109 9HX 0.9653
110 HPY 0.9652
111 25R 0.9652
112 BZX 0.9651
113 PXY 0.9651
114 1WG 0.9649
115 PCR 0.9646
116 ARB 0.9645
117 FPN 0.9640
118 2CH 0.9638
119 285 0.9638
120 IDM 0.9634
121 DA1 0.9630
122 3Z7 0.9629
123 PM6 0.9628
124 JZ9 0.9627
125 AMC 0.9626
126 F05 0.9625
127 CYH 0.9622
128 LG4 0.9621
129 150 0.9618
130 6AI 0.9618
131 ES4 0.9616
132 HTS 0.9615
133 282 0.9610
134 BTE 0.9609
135 FUL 0.9607
136 LCN 0.9606
137 CIG 0.9604
138 RIB 0.9604
139 HMH 0.9599
140 YAN 0.9598
141 FPI 0.9593
142 FUC 0.9592
143 4XX 0.9592
144 DAB 0.9588
145 L3Q 0.9587
146 3MC 0.9586
147 HAI 0.9584
148 286 0.9582
149 2CQ 0.9581
150 J1Z 0.9577
151 MRY 0.9573
152 4H2 0.9572
153 TH7 0.9572
154 25W 0.9572
155 6X8 0.9571
156 4CH 0.9570
157 TMT 0.9569
158 9EW 0.9569
159 ASO 0.9569
160 7CZ 0.9569
161 ECE 0.9569
162 23A 0.9568
163 JZ3 0.9568
164 M3T 0.9567
165 7MH 0.9567
166 0R0 0.9566
167 45C 0.9566
168 JFD 0.9562
169 BP1 0.9561
170 5H1 0.9561
171 1DW 0.9560
172 4HS 0.9558
173 HEW 0.9556
174 PYG 0.9553
175 3XX 0.9550
176 NOY 0.9550
177 SYN 0.9549
178 F60 0.9548
179 14O 0.9547
180 3DO 0.9546
181 AZF 0.9543
182 G2F 0.9541
183 FFP 0.9540
184 64K 0.9540
185 R1X 0.9538
186 5MB 0.9536
187 NOJ 0.9534
188 CXL 0.9534
189 JZ1 0.9533
190 3FA 0.9532
191 B3R 0.9532
192 2XX 0.9529
193 HBX 0.9529
194 FUF 0.9526
195 GMN 0.9525
196 MBD 0.9523
197 HX3 0.9522
198 T6C 0.9520
199 JAE 0.9519
200 BML 0.9519
201 270 0.9518
202 F4Z 0.9517
203 OXQ 0.9517
204 5MI 0.9513
205 ABN 0.9513
206 DFB 0.9512
207 B53 0.9509
208 2K4 0.9508
209 QUZ 0.9508
210 SAL 0.9508
211 HGQ 0.9506
212 TMZ 0.9505
213 2MY 0.9503
214 TM4 0.9503
215 V1L 0.9501
216 M1A 0.9500
217 SVN 0.9500
218 1MR 0.9500
219 G6D 0.9500
220 4JN 0.9500
221 2C9 0.9499
222 ICF 0.9499
223 BEZ 0.9499
224 Q88 0.9498
225 MLT 0.9497
226 GLC 0.9497
227 FCA 0.9496
228 DTL 0.9494
229 R8A 0.9492
230 4ZC 0.9491
231 ES0 0.9491
232 ICC 0.9490
233 FLM 0.9489
234 PYF 0.9489
235 NBE 0.9489
236 ES9 0.9489
237 0RW 0.9489
238 HLR 0.9489
239 47J 0.9486
240 HBA 0.9486
241 TC7 0.9485
242 PY7 0.9485
243 3CE 0.9482
244 OAA 0.9479
245 ARA 0.9478
246 GBD 0.9477
247 IMR 0.9476
248 AX7 0.9475
249 ADZ 0.9474
250 F81 0.9472
251 6M4 0.9469
252 BEN 0.9469
253 11S 0.9461
254 NPY 0.9458
255 BAM 0.9456
256 CWM 0.9455
257 IOL 0.9455
258 23W 0.9454
259 FUB 0.9454
260 HHQ 0.9451
261 MAK 0.9448
262 6PC 0.9445
263 PHB 0.9445
264 P92 0.9443
265 280 0.9439
266 YCP 0.9439
267 2MI 0.9436
268 GAG 0.9434
269 URQ 0.9434
270 XQ0 0.9433
271 Z6J 0.9433
272 HY3 0.9432
273 67N 0.9431
274 NCA 0.9431
275 3U4 0.9429
276 12M 0.9429
277 IPH 0.9429
278 6MH 0.9428
279 4VP 0.9428
280 FK1 0.9427
281 2CM 0.9426
282 XXR 0.9425
283 DGJ 0.9423
284 A2Q 0.9423
285 F5B 0.9422
286 7W4 0.9421
287 MBN 0.9421
288 ABV 0.9419
289 KKN 0.9415
290 ISN 0.9415
291 1SQ 0.9414
292 WDL 0.9413
293 6HQ 0.9411
294 LMR 0.9410
295 1LQ 0.9410
296 H4N 0.9410
297 2AP 0.9408
298 HVK 0.9408
299 9PO 0.9408
300 G4D 0.9408
301 APY 0.9407
302 JZ7 0.9406
303 FCB 0.9405
304 BE2 0.9403
305 PZA 0.9403
306 HRZ 0.9403
307 6M9 0.9403
308 82I 0.9401
309 35C 0.9400
310 4AP 0.9400
311 QOS 0.9400
312 5WV 0.9399
313 5Q0 0.9398
314 NBZ 0.9398
315 IFL 0.9397
316 JPZ 0.9396
317 V55 0.9396
318 VGL 0.9395
319 4HM 0.9395
320 IF7 0.9395
321 1NP 0.9394
322 LER 0.9394
323 5SG 0.9393
324 ES1 0.9393
325 DUB 0.9393
326 4SV 0.9392
327 2DR 0.9392
328 FE DB1 0.9390
329 WOT 0.9390
330 4M4 0.9390
331 EUG 0.9390
332 NIO 0.9390
333 2IM 0.9389
334 1LM 0.9388
335 3AP 0.9388
336 5IQ 0.9387
337 DBH 0.9385
338 3RK 0.9383
339 HIU 0.9383
340 HQY 0.9381
341 LGA 0.9381
342 4YS 0.9379
343 7B4 0.9379
344 C2A 0.9379
345 AX2 0.9379
346 5AC 0.9378
347 3HA 0.9377
348 2A9 0.9377
349 RM4 0.9377
350 9DG 0.9374
351 3F0 0.9373
352 ES6 0.9373
353 N5J 0.9373
354 6UA 0.9373
355 PRO 0.9373
356 8NY 0.9372
357 FBA 0.9370
358 AGK 0.9370
359 5AN 0.9370
360 ES7 0.9369
361 3MH 0.9369
362 GAL 0.9368
363 RNS 0.9366
364 FOA 0.9366
365 F0J 0.9365
366 6AP 0.9365
367 JBH 0.9365
368 A2F 0.9364
369 YHO 0.9364
370 MFB 0.9363
371 3M0 0.9361
372 AZG 0.9360
373 L60 0.9360
374 GXE 0.9359
375 2CK 0.9359
376 NEQ 0.9359
377 YTB 0.9358
378 XM0 0.9358
379 CEJ 0.9357
380 PYC 0.9357
381 KIV 0.9355
382 3AY 0.9354
383 SWD 0.9353
384 LDU 0.9353
385 24W 0.9353
386 BR8 0.9352
387 GUN 0.9350
388 GIF 0.9350
389 ALO 0.9347
390 8CL 0.9346
391 RAM 0.9346
392 GYE 0.9346
393 93B 0.9345
394 IGA 0.9342
395 LRH 0.9342
396 G3F 0.9342
397 9CL 0.9340
398 290 0.9337
399 4NC 0.9337
400 MB3 0.9337
401 TBP 0.9336
402 7EX 0.9336
403 3ID 0.9334
404 141 0.9331
405 5ZE 0.9331
406 VAL 0.9331
407 QSC 0.9330
408 9X7 0.9330
409 265 0.9330
410 13X 0.9327
411 PYJ 0.9327
412 BE7 0.9326
413 BGC 0.9326
414 4JL 0.9325
415 2KT 0.9324
416 UNU 0.9321
417 CFP 0.9319
418 AZA 0.9318
419 4CS 0.9316
420 3SL 0.9315
421 1XM 0.9314
422 XAN 0.9313
423 DMD 0.9309
424 1P7 0.9307
425 GCS 0.9307
426 8GC 0.9307
427 S76 0.9303
428 DGY 0.9303
429 HH8 0.9302
430 H8N 0.9302
431 ADK 0.9301
432 60P 0.9301
433 5RG 0.9300
434 03V 0.9298
435 KG7 0.9296
436 2D0 0.9295
437 JB5 0.9295
438 C2B 0.9294
439 2ZX 0.9292
440 NTN 0.9292
441 EXO 0.9292
442 COU 0.9290
443 2PC 0.9290
444 NMJ 0.9287
445 1WD 0.9286
446 5CU 0.9285
447 YH7 0.9284
448 BOA 0.9283
449 ASN 0.9280
450 SOE 0.9280
451 RUU 0.9279
452 SPV 0.9279
453 6CS 0.9278
454 HY1 0.9277
455 3SK 0.9276
456 PCA 0.9276
457 P3K 0.9274
458 1DU 0.9274
459 QWN 0.9272
460 GOO 0.9272
461 CIZ 0.9272
462 8S0 0.9272
463 R8S 0.9271
464 B24 0.9271
465 LGC 0.9269
466 GIO 0.9268
467 HUI 0.9268
468 DX4 0.9267
469 1XN 0.9267
470 TP5 0.9267
471 4XH 0.9266
472 TZC 0.9266
473 KSW 0.9266
474 2A7 0.9264
475 EQT 0.9262
476 VNJ 0.9262
477 3NT 0.9260
478 2AQ 0.9259
479 DTI 0.9258
480 JKE 0.9257
481 PRS 0.9257
482 BP9 0.9256
483 DHB 0.9256
484 BHO 0.9255
485 JBE 0.9254
486 TTO 0.9254
487 MNM 0.9254
488 8EZ 0.9251
489 KYD 0.9251
490 DXX 0.9250
491 RSO 0.9250
492 DOB 0.9249
493 HZP 0.9248
494 3PY 0.9247
495 MZ0 0.9247
496 ITN 0.9246
497 5B1 0.9245
498 GTQ 0.9245
499 DSN 0.9245
500 MLI 0.9243
501 OHG 0.9242
502 4FS 0.9239
503 ES5 0.9237
504 HSL 0.9237
505 ERH 0.9235
506 HH5 0.9234
507 4AX 0.9234
508 DMJ 0.9234
509 SS1 0.9233
510 DMG 0.9233
511 H42 0.9232
512 KPL 0.9230
513 6LW 0.9230
514 BHA 0.9229
515 3MA 0.9228
516 5HN 0.9227
517 KBG 0.9227
518 FA0 0.9226
519 HHN 0.9225
520 94N 0.9224
521 SJ5 0.9224
522 HSE 0.9223
523 2RA 0.9223
524 SEJ 0.9223
525 JAB 0.9221
526 HYN 0.9220
527 DAS 0.9220
528 FP1 0.9219
529 QXW 0.9218
530 24T 0.9218
531 25T 0.9217
532 XX2 0.9217
533 I3A 0.9217
534 DPR 0.9217
535 SER 0.9217
536 GAB 0.9217
537 4JM 0.9214
538 94B 0.9214
539 WOO 0.9213
540 TAR 0.9212
541 DBB 0.9211
542 A3B 0.9211
543 4M0 0.9210
544 OCH 0.9209
545 MMZ 0.9209
546 260 0.9209
547 IPB 0.9208
548 5M0 0.9207
549 ILE 0.9207
550 1LN 0.9207
551 7WV 0.9206
552 278 0.9205
553 9TY 0.9205
554 ISE 0.9204
555 7HQ 0.9203
556 UYA 0.9203
557 GLA 0.9202
558 NPO 0.9202
559 FAN 0.9201
560 3DM 0.9201
561 AC0 0.9200
562 FDB 0.9198
563 GRE 0.9198
564 BVC 0.9198
565 TEO 0.9198
566 CYS 0.9198
567 P9P 0.9197
568 TLA 0.9197
569 ET2 0.9196
570 ABA 0.9196
571 BCP 0.9196
572 BSX 0.9195
573 ALL 0.9195
574 H76 0.9194
575 6GU 0.9194
576 3HB 0.9194
577 M58 0.9193
578 948 0.9193
579 7VJ 0.9192
580 TZE 0.9192
581 273 0.9191
582 9TZ 0.9190
583 AFR 0.9189
584 3AB 0.9189
585 2ZV 0.9188
586 IQ0 0.9187
587 XIX 0.9186
588 PXL 0.9186
589 GAF 0.9186
590 JBN 0.9185
591 C5J 0.9184
592 2FG 0.9183
593 MRZ 0.9183
594 MYJ 0.9182
595 INO 0.9178
596 54G 0.9177
597 HHA 0.9175
598 2HO 0.9175
599 GXL 0.9175
600 AKB 0.9174
601 TFB 0.9173
602 MLA 0.9173
603 OVV 0.9172
604 36R 0.9172
605 CRN 0.9172
606 CLW 0.9171
607 PBC 0.9171
608 PAF 0.9171
609 717 0.9166
610 54D 0.9163
611 GLU 0.9162
612 0CU 0.9161
613 RM1 0.9161
614 9YL 0.9161
615 1DH 0.9161
616 URC 0.9159
617 1P8 0.9158
618 SMV 0.9158
619 NNO 0.9157
620 THR 0.9157
621 HYP 0.9156
622 PIH 0.9156
623 E60 0.9155
624 HGW 0.9154
625 93K 0.9153
626 IT2 0.9153
627 DTU 0.9153
628 3HM 0.9152
629 X6X 0.9152
630 FPK 0.9152
631 5VM 0.9151
632 3OC 0.9149
633 6F0 0.9149
634 PXM 0.9148
635 1GN 0.9148
636 VGD 0.9147
637 FLA 0.9146
638 URP 0.9146
639 DMI 0.9144
640 JLZ 0.9143
641 INS 0.9143
642 HX2 0.9142
643 4A3 0.9141
644 UEG 0.9141
645 NVA 0.9141
646 261 0.9138
647 JBK 0.9136
648 NXA 0.9136
649 DIE 0.9136
650 FHB 0.9134
651 BVG 0.9134
652 5MK 0.9133
653 3BZ 0.9132
654 VOH 0.9132
655 GLF 0.9131
656 WCE 0.9130
657 53C 0.9130
658 GIV 0.9130
659 C21 0.9128
660 6M1 0.9128
661 14J 0.9128
662 XQG 0.9127
663 SIN 0.9127
664 O7U 0.9127
665 9TW 0.9125
666 5JQ 0.9124
667 2LP 0.9124
668 XBT 0.9123
669 NVI 0.9122
670 42A 0.9122
671 M2H 0.9120
672 ZZ3 0.9120
673 BTY 0.9119
674 LZM 0.9119
675 YIO 0.9119
676 HJP 0.9118
677 FEH 0.9118
678 BRT 0.9115
679 0W8 0.9115
680 B55 0.9109
681 8TX 0.9109
682 ASP 0.9109
683 VNL 0.9106
684 5XC 0.9103
685 FRU 0.9103
686 0P6 0.9102
687 75K 0.9101
688 2H5 0.9101
689 FBB 0.9099
690 4JT 0.9098
691 IP0 0.9096
692 PA1 0.9096
693 SWA 0.9096
694 CN0 0.9095
695 B57 0.9094
696 KJY 0.9093
697 XLS 0.9093
698 KT7 0.9092
699 2EC 0.9091
700 FH2 0.9091
701 149 0.9091
702 9MG 0.9088
703 5OB 0.9087
704 ES2 0.9085
705 32O 0.9084
706 HIO 0.9082
707 PBE 0.9082
708 MSN 0.9082
709 SX1 0.9081
710 K2T 0.9081
711 MAE 0.9080
712 CHB 0.9079
713 TCZ 0.9079
714 JFJ 0.9079
715 DCY 0.9078
716 98J 0.9078
717 51F 0.9077
718 PAB 0.9077
719 SRT 0.9074
720 BDF 0.9074
721 Z82 0.9074
722 5JL 0.9070
723 86J 0.9070
724 1P3 0.9069
725 BZ3 0.9067
726 FDK 0.9067
727 1Y6 0.9067
728 ZBT 0.9065
729 XYL 0.9065
730 RB5 0.9065
731 BDP 0.9064
732 BMA 0.9063
733 FOT 0.9063
734 CWS 0.9061
735 OXC 0.9060
736 N7P 0.9057
737 O72 0.9056
738 HCS 0.9056
739 DHK 0.9055
740 MR1 0.9055
741 RHU 0.9054
742 R8V 0.9054
743 8IG 0.9053
744 SS2 0.9053
745 LYL 0.9052
746 8CM 0.9048
747 UY7 0.9047
748 CFI 0.9046
749 GXY 0.9045
750 QSB 0.9044
751 N8P 0.9044
752 NIZ 0.9043
753 PE0 0.9041
754 CGB 0.9039
755 XAZ 0.9037
756 FQI 0.9037
757 5CL 0.9036
758 40E 0.9036
759 DOR 0.9036
760 XUL 0.9033
761 IJZ 0.9032
762 UNC 0.9032
763 MAN 0.9031
764 DIG 0.9030
765 JZ4 0.9030
766 SHG 0.9026
767 95Z 0.9025
768 ORO 0.9022
769 KUF 0.9021
770 PZI 0.9020
771 ZXD 0.9019
772 UGC 0.9018
773 3V4 0.9016
774 IOM 0.9016
775 ISZ 0.9015
776 Q24 0.9014
777 BNS 0.9013
778 ARW 0.9012
779 174 0.9007
780 I2M 0.9007
781 DBJ 0.9006
782 MZW 0.9006
783 JZ5 0.9005
784 PRY 0.9005
785 HFB 0.9005
786 M6N 0.9004
787 6KX 0.9004
788 7W1 0.9003
789 39A 0.9003
790 PBZ 0.9003
791 HVQ 0.9001
792 MEW 0.9000
793 2MN 0.8999
794 8WT 0.8997
795 LDP 0.8996
796 MBG 0.8996
797 AQO 0.8995
798 CXF 0.8995
799 FW5 0.8995
800 QBK 0.8994
801 AZ8 0.8993
802 HBD 0.8992
803 LFR 0.8989
804 7WG 0.8986
805 LEU 0.8986
806 A7W 0.8986
807 826 0.8983
808 EKZ 0.8983
809 5QX 0.8981
810 PZM 0.8981
811 SF9 0.8980
812 3WA 0.8979
813 4AA 0.8978
814 M5K 0.8976
815 MRW 0.8976
816 SHA 0.8975
817 ZWZ 0.8975
818 IHB 0.8974
819 3Z8 0.8974
820 FBM 0.8973
821 XIY 0.8973
822 E7Z 0.8972
823 SW7 0.8971
824 HDA 0.8969
825 4MA 0.8968
826 69O 0.8966
827 A65 0.8964
828 1M2 0.8963
829 2HQ 0.8962
830 PEA 0.8962
831 192 0.8961
832 F9P 0.8960
833 QX2 0.8958
834 P2D 0.8957
835 HLZ 0.8953
836 4PW 0.8949
837 ORN 0.8948
838 HZQ 0.8947
839 IV2 0.8947
840 IPZ 0.8947
841 FA1 0.8947
842 TTL 0.8942
843 2EZ 0.8941
844 QWW 0.8940
845 32X 0.8940
846 PEL 0.8940
847 AUD 0.8939
848 4FA 0.8939
849 4HC 0.8938
850 AC6 0.8938
851 8WO 0.8938
852 1AC 0.8937
853 34D 0.8936
854 GLT 0.8936
855 DHS 0.8936
856 MXN 0.8936
857 I1N 0.8935
858 KJH 0.8934
859 G5V 0.8934
860 C2U 0.8933
861 J9W 0.8933
862 DIN 0.8930
863 JBQ 0.8929
864 7VS 0.8929
865 MNN 0.8924
866 12Q 0.8923
867 7N0 0.8923
868 PAV 0.8923
869 1DJ 0.8923
870 SGL 0.8923
871 5WX 0.8922
872 AW5 0.8918
873 HQT 0.8918
874 MWP 0.8918
875 P72 0.8917
876 DQN 0.8916
877 MT0 0.8915
878 BCF 0.8913
879 XRG 0.8913
880 F9Y 0.8911
881 ASC 0.8909
882 DIU 0.8906
883 CTL 0.8905
884 DHQ 0.8904
885 495 0.8899
886 1DQ 0.8898
887 SNE 0.8898
888 5RN 0.8898
889 LT2 0.8897
890 KP6 0.8896
891 DYA 0.8896
892 F31 0.8896
893 AJ2 0.8894
894 D1X 0.8893
895 MO8 0.8893
896 7NI 0.8892
897 BBF 0.8891
898 OK7 0.8890
899 MFU 0.8888
900 NDH 0.8888
901 4Z4 0.8887
902 M1Q 0.8887
903 JA8 0.8886
904 271 0.8886
905 Q6T 0.8885
906 TMH 0.8883
907 GDE 0.8882
908 EA1 0.8880
909 FBV 0.8877
910 PFB 0.8877
911 AAE 0.8870
912 M1E 0.8867
913 2TQ 0.8866
914 KIB 0.8865
915 KIA 0.8865
916 51R 0.8862
917 F3B 0.8859
918 HSM 0.8859
919 T2C 0.8859
920 2BG 0.8857
921 COI 0.8857
922 SKA 0.8854
923 NDM 0.8852
924 M0Q 0.8852
925 K5W 0.8849
926 MQN 0.8845
927 TPA 0.8845
928 G3E 0.8845
929 CEE 0.8844
930 ODV 0.8839
931 4YO 0.8837
932 GCB 0.8837
933 TEP 0.8836
934 5DI 0.8836
935 42C 0.8835
936 SYV 0.8834
937 DRL 0.8833
938 OVM 0.8829
939 DBX 0.8829
940 TIU 0.8829
941 IFP 0.8828
942 42J 0.8827
943 BAE 0.8827
944 KMT 0.8827
945 SKM 0.8826
946 3PF 0.8826
947 FGZ 0.8826
948 HIS 0.8826
949 1DV 0.8825
950 5QY 0.8822
951 4P5 0.8819
952 3MB 0.8817
953 AKH 0.8817
954 PTO 0.8817
955 GCU 0.8817
956 PEP 0.8816
957 NTM 0.8815
958 HXX 0.8815
959 H7Y 0.8814
960 173 0.8813
961 II6 0.8812
962 IBF 0.8810
963 3MT 0.8810
964 PCI 0.8808
965 CSS 0.8808
966 EV0 0.8806
967 AC5 0.8806
968 2GS 0.8806
969 3MG 0.8804
970 2AL 0.8804
971 PHT 0.8802
972 7D2 0.8802
973 KLW 0.8801
974 2PG 0.8800
975 FB1 0.8800
976 TFU 0.8799
977 CTS 0.8797
978 3IT 0.8797
979 OXL 0.8796
980 6RQ 0.8790
981 MUA 0.8788
982 3FH 0.8788
983 SVD 0.8786
984 4XV 0.8785
985 0TU 0.8783
986 M2K 0.8783
987 PGA 0.8783
988 AMG 0.8782
989 CP 0.8782
990 329 0.8781
991 4JQ 0.8780
992 8ZE 0.8779
993 ZB1 0.8779
994 GLY PRO 0.8778
995 5RO 0.8777
996 QY9 0.8777
997 PAC 0.8777
998 EVA 0.8777
999 44V 0.8776
1000 PKU 0.8775
1001 9X6 0.8775
1002 ADA 0.8771
1003 0JD 0.8771
1004 OXM 0.8771
1005 7MU 0.8769
1006 PYR 0.8769
1007 EYK 0.8768
1008 BAQ 0.8765
1009 PMB 0.8765
1010 DZX 0.8762
1011 LKA 0.8762
1012 XHP 0.8760
1013 SE2 0.8760
1014 LSA 0.8758
1015 OXD 0.8757
1016 AMT 0.8756
1017 ICO 0.8756
1018 OW4 0.8755
1019 FBT 0.8755
1020 IVA 0.8754
1021 RMN 0.8754
1022 37T 0.8752
1023 ATQ 0.8752
1024 SF6 0.8751
1025 SR1 0.8749
1026 B62 0.8748
1027 AEF 0.8747
1028 R9S 0.8745
1029 QSH 0.8744
1030 YRL 0.8741
1031 0V5 0.8739
1032 4SD 0.8737
1033 XCZ 0.8734
1034 D48 0.8734
1035 4XS 0.8734
1036 MET 0.8734
1037 GTR 0.8734
1038 PHU 0.8734
1039 J5I 0.8733
1040 JND 0.8731
1041 AEH 0.8731
1042 X0V 0.8731
1043 1CB 0.8729
1044 FB2 0.8728
1045 GLL 0.8725
1046 EOL 0.8724
1047 B2J 0.8724
1048 PYQ 0.8723
1049 GBL 0.8721
1050 SXS 0.8718
1051 1U6 0.8717
1052 SOR 0.8715
1053 2OP 0.8707
1054 5GU 0.8705
1055 44W 0.8704
1056 NCM 0.8704
1057 KJU 0.8702
1058 FBW 0.8698
1059 B60 0.8697
1060 3TR 0.8696
1061 TNE 0.8696
1062 TSU 0.8695
1063 E5X 0.8695
1064 LNR 0.8694
1065 AZ9 0.8694
1066 ABU 0.8692
1067 TSS 0.8691
1068 PSV 0.8691
1069 PAE 0.8691
1070 HOW 0.8686
1071 JXN 0.8684
1072 PRF 0.8684
1073 MR3 0.8683
1074 OTW 0.8681
1075 680 0.8681
1076 12B 0.8679
1077 ENL 0.8678
1078 1MZ 0.8678
1079 LAC 0.8677
1080 GJS 0.8676
1081 2MZ 0.8675
1082 0HO 0.8675
1083 DHR 0.8673
1084 2AI 0.8673
1085 KBB 0.8671
1086 4MZ 0.8671
1087 A13 0.8670
1088 DQU 0.8669
1089 GM7 0.8668
1090 92K 0.8665
1091 DCD 0.8664
1092 YSO 0.8663
1093 0FO 0.8662
1094 GZL 0.8662
1095 PQ0 0.8657
1096 8OZ 0.8657
1097 BEA 0.8654
1098 HGY 0.8654
1099 SFU 0.8650
1100 4SX 0.8650
1101 OVP 0.8646
1102 DAL 0.8645
1103 AKG 0.8643
1104 HQD 0.8642
1105 VK3 0.8640
1106 AH8 0.8640
1107 S0H 0.8639
1108 FCN 0.8638
1109 NIS 0.8637
1110 NQ 0.8632
1111 FA3 0.8632
1112 B20 0.8629
1113 6JN 0.8627
1114 4FH 0.8624
1115 N2I 0.8624
1116 BUO 0.8622
1117 1F1 0.8621
1118 YQA 0.8620
1119 2FY 0.8619
1120 TTY 0.8619
1121 PYM 0.8618
1122 5KX 0.8616
1123 0HN 0.8614
1124 ALA 0.8608
1125 KDV 0.8606
1126 4ZA 0.8604
1127 APZ 0.8603
1128 TB6 0.8603
1129 MMA 0.8602
1130 PNZ 0.8602
1131 IHG 0.8600
1132 SYG 0.8597
1133 G1O 0.8596
1134 4NM 0.8594
1135 3NY 0.8594
1136 BNZ 0.8591
1137 T9G 0.8589
1138 NK2 0.8589
1139 0PY 0.8589
1140 FCR 0.8588
1141 ANN 0.8587
1142 RXA 0.8585
1143 JUG 0.8584
1144 GOL 0.8584
1145 UAN 0.8583
1146 2ZM 0.8583
1147 H62 0.8581
1148 6NT 0.8577
1149 259 0.8577
1150 MZB 0.8575
1151 N8Y 0.8574
1152 4WL 0.8574
1153 MVN 0.8566
1154 TBS 0.8565
1155 NAK 0.8564
1156 PHZ 0.8562
1157 5Y9 0.8559
1158 TWO 0.8556
1159 GJZ 0.8555
1160 P1R 0.8551
1161 INE 0.8547
1162 K17 0.8544
1163 SAR 0.8542
1164 ABI 0.8539
1165 BAL 0.8537
1166 BYZ 0.8535
1167 5NI 0.8520
1168 3A9 0.8514
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3EUF; Ligand: BAU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3euf.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 3EUF; Ligand: BAU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 3euf.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 3EUF; Ligand: BAU; Similar sites found with APoc: 2
This union binding pocket(no: 3) in the query (biounit: 3euf.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 3BJE URA 30.4878
2 3BJE URA 30.4878
Pocket No.: 4; Query (leader) PDB : 3EUF; Ligand: BAU; Similar sites found with APoc: 2
This union binding pocket(no: 4) in the query (biounit: 3euf.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 3BJE URA 30.4878
2 3BJE URA 30.4878
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