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Receptor
PDB id Resolution Class Description Source Keywords
3MJH 2.03 Å EC: 3.6.5.2 CRYSTAL STRUCTURE OF HUMAN RAB5A IN COMPLEX WITH THE C2H2 ZI OF EEA1 HOMO SAPIENS PROTEIN-ZINC FINGER COMPLEX BETA BETA ALPHA FOLD BETA HAIRRAB5A GTPASE EEA1 PROTEIN TRANSPORT
Ref.: STRUCTURAL BASIS FOR RAB GTPASE RECOGNITION AND END TETHERING BY THE C2H2 ZINC FINGER OF EARLY ENDOSOMA AUTOANTIGEN 1 (EEA1). PROC.NATL.ACAD.SCI.USA V. 107 10866 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:200;
C:200;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:201;
C:201;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ZN B:70;
D:70;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3MJH 2.03 Å EC: 3.6.5.2 CRYSTAL STRUCTURE OF HUMAN RAB5A IN COMPLEX WITH THE C2H2 ZI OF EEA1 HOMO SAPIENS PROTEIN-ZINC FINGER COMPLEX BETA BETA ALPHA FOLD BETA HAIRRAB5A GTPASE EEA1 PROTEIN TRANSPORT
Ref.: STRUCTURAL BASIS FOR RAB GTPASE RECOGNITION AND END TETHERING BY THE C2H2 ZINC FINGER OF EARLY ENDOSOMA AUTOANTIGEN 1 (EEA1). PROC.NATL.ACAD.SCI.USA V. 107 10866 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 3MJH - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 3MJH - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (47)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 3QBT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 5WFO - 5UU C19 H16 Cl F N2 c1cc(ccc1N....
3 6FA3 Kd = 0.038 uM D1Z C30 H36 N4 O5 CN(C)Cc1cc....
4 5WFQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
5 5O2T Kd = 3.9 nM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
6 5WPM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 5WFR - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 5UFQ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 6AMB - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
10 6FA1 - D2Z C20 H25 N2 O4 C[NH+](C)C....
11 5UFE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 5WFP - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 5WHB - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 5WPL - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
15 5XCO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 1NVU - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
17 5WHE - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
18 3KUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
19 1C1Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
20 5TAR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
21 4DXA - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
22 4HDO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
23 3MJH - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
24 5E95 Kd = 15.7 nM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
25 3CF6 - SP1 C10 H12 N5 O5 P S c1nc(c2c(n....
26 2CJW Kd = 2.5 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
27 6FA4 Kd = 0.051 uM D1W C23 H25 N3 O3 CN(C)Cc1cc....
28 2C5L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
29 4K81 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
30 1LFD - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
31 4KVG - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
32 3TNF - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
33 1ZC4 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
34 1ZC3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
35 2A9K - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
36 2A78 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
37 1WQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
38 3TKL - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
39 3DDC - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
40 3KUD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
41 1TU3 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
42 1UAD Ka = 7260000 M^-1 GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
43 5O74 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
44 3SFV - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
45 4URZ Kd = 3 mM VJP C11 H14 N2 O3 S c1cc(ccc1N....
46 4URX Kd = 1.3 mM HXY C11 H14 Br N c1cc(ccc1C....
47 4URY Kd = 6 mM RV1 C10 H12 N2 O3 S c1cc(ccc1N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 156
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 9GM 0.809524 0.973684
9 GNP 0.809524 0.973684
10 GCP 0.797619 0.973684
11 5GP 0.797468 0.986486
12 G 0.797468 0.986486
13 GMV 0.764706 0.973684
14 G2R 0.764045 0.961039
15 G5P 0.755319 0.973684
16 GTG 0.752688 0.936709
17 G2P 0.747126 0.961039
18 G3A 0.744681 0.973684
19 GDD 0.741935 0.961039
20 GDC 0.741935 0.961039
21 GKE 0.741935 0.961039
22 0O2 0.736264 0.986486
23 GP2 0.729412 0.961039
24 6CK 0.726316 0.936709
25 Y9Z 0.723404 0.902439
26 GPG 0.717391 0.961039
27 GFB 0.715789 0.961039
28 GDR 0.715789 0.961039
29 GPD 0.704082 0.925
30 GKD 0.693878 0.961039
31 JB2 0.693878 0.961039
32 GDX 0.686869 0.973684
33 ALF 5GP 0.685393 0.888889
34 GH3 0.681319 0.973333
35 YGP 0.677083 0.901235
36 G3D 0.67033 0.986486
37 GDP AF3 0.659574 0.888889
38 ALF GDP 0.659574 0.888889
39 GDP ALF 0.659574 0.888889
40 DGT 0.659341 0.923077
41 GMP 0.658228 0.88
42 G4P 0.655914 0.986486
43 JB3 0.653846 0.948718
44 NGD 0.647619 0.961039
45 CAG 0.642202 0.880952
46 2MD 0.62963 0.891566
47 MGP 0.619565 0.961039
48 U2G 0.616822 0.936709
49 6G0 0.612903 0.961039
50 MGD 0.612613 0.891566
51 TPG 0.608696 0.840909
52 CG2 0.605505 0.936709
53 GDP 7MG 0.601942 0.911392
54 FEG 0.601852 0.879518
55 G G 0.598039 0.948052
56 ZGP 0.59633 0.869048
57 PGD 0.591304 0.925
58 MD1 0.591304 0.891566
59 3GP 0.590909 0.946667
60 GPX 0.581633 0.946667
61 DGI 0.580645 0.923077
62 IDP 0.576087 0.972973
63 DBG 0.567797 0.948718
64 2GP 0.555556 0.96
65 FE9 0.555556 0.776596
66 G4M 0.547619 0.880952
67 BGO 0.544643 0.924051
68 GCP G 0.543689 0.921053
69 ATP 0.537634 0.92
70 HEJ 0.537634 0.92
71 G1G 0.533898 0.925
72 AQP 0.531915 0.92
73 5FA 0.531915 0.92
74 A G 0.525862 0.935065
75 G A A A 0.525862 0.923077
76 U A G G 0.521368 0.935065
77 HFD 0.520833 0.873418
78 R5I 0.520408 0.946667
79 R7I 0.520408 0.946667
80 01G 0.518868 0.902439
81 P2G 0.510638 0.883117
82 ITT 0.510638 0.868421
83 AKW 0.504348 0.890244
84 GGM 0.504274 0.901235
85 G1R G1R 0.504065 0.924051
86 DGP 0.5 0.910256
87 PGD O 0.5 0.850575
88 MGO 0.5 0.864198
89 DG 0.5 0.910256
90 P1G 0.5 0.871795
91 GTA 0.495495 0.936709
92 PRT 0.490741 0.959459
93 B4P 0.489362 0.894737
94 AP5 0.489362 0.894737
95 IMP 0.489362 0.959459
96 G U 0.487179 0.9
97 7DT 0.484536 0.906667
98 GPC 0.479339 0.879518
99 G C 0.478992 0.9
100 BA3 0.478723 0.894737
101 ADP 0.473684 0.92
102 G2Q 0.471698 0.961039
103 6YZ 0.470588 0.896104
104 G7M 0.46875 0.948052
105 C1Z 0.462963 0.986486
106 25L 0.458716 0.907895
107 A2D 0.457447 0.894737
108 RGT 0.45045 0.909091
109 AGS 0.45 0.873418
110 SAP 0.45 0.873418
111 SGP 0.44898 0.82716
112 A4P 0.445378 0.869048
113 G G G RPC 0.442623 0.875
114 ANP 0.441176 0.896104
115 ACQ 0.441176 0.896104
116 8GT 0.441176 0.875
117 APC G U 0.44 0.886076
118 AT4 0.438776 0.884615
119 G U34 0.438017 0.888889
120 6AD 0.436893 0.841463
121 G G G C 0.433071 0.9125
122 UP5 0.432203 0.873418
123 PCG 0.431373 0.933333
124 C2E 0.431373 0.921053
125 35G 0.431373 0.933333
126 A G C C 0.429688 0.911392
127 T99 0.427184 0.884615
128 5GP 5GP 0.427184 0.883117
129 TAT 0.427184 0.884615
130 AR6 0.425743 0.894737
131 APR 0.425743 0.894737
132 7DD 0.424242 0.906667
133 AN2 0.424242 0.907895
134 DG DG 0.423423 0.865854
135 AD9 0.421569 0.896104
136 M33 0.42 0.883117
137 7D4 0.42 0.835443
138 UCG 0.419847 0.911392
139 HDV 0.419048 0.825
140 H6Y 0.419048 0.946667
141 G C C C 0.416667 0.924051
142 ACP 0.415842 0.896104
143 T5A 0.414634 0.802326
144 A1R 0.412844 0.839506
145 ADQ 0.412844 0.871795
146 MGQ 0.412844 0.935897
147 A3R 0.412844 0.839506
148 MGT 0.411215 0.823529
149 A G U 0.410072 0.888889
150 93A 0.41 0.833333
151 A22 0.407407 0.907895
152 CA0 0.405941 0.896104
153 ATF 0.40566 0.884615
154 AGO 0.404762 0.888889
155 MGV 0.401786 0.890244
156 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3MJH; Ligand: GTP; Similar sites found with APoc: 572
This union binding pocket(no: 1) in the query (biounit: 3mjh.bio2) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1A4R GNH None
2 1A4R GDP None
3 1GRN GDP None
4 1GRN AF3 None
5 2PZE ATP None
6 2NGR GDP None
7 1JJV ATP None
8 2OBM ADP None
9 2NGR AF3 None
10 3DKP ADP None
11 1GXU 2HP None
12 2IYL GDP None
13 2BEK ATP None
14 2PEZ GGZ None
15 2PEZ DAT None
16 3QXC ATP None
17 4QRH 0O2 None
18 1NN5 2DT None
19 1NN5 ANP None
20 1A78 TDG None
21 4PTN PYR None
22 4QAG F95 None
23 6E8I PTR None
24 1ONI BEZ None
25 4ZNL BEF ADP None
26 1V3S ATP None
27 2IL4 COA None
28 2W58 ADP 1.19048
29 3A4M ADP 1.19048
30 4V03 ADP 1.19048
31 1TL2 NDG 1.19048
32 3I8T LBT 1.21951
33 4LC1 GDP 1.78571
34 1FP6 ADP 1.78571
35 5L3W GDP 1.78571
36 5M7P ADP 1.78571
37 4DID GDP 1.97368
38 4ITR GDP 2.38095
39 3B5J 12D 2.38095
40 1XX6 ADP 2.38095
41 2GDJ ANP 2.38095
42 4FCW ADP 2.38095
43 4D81 ADP 2.38095
44 4LJ9 ACP 2.38095
45 6B4K ANP 2.38095
46 5AK0 8V1 2.38095
47 2OFW ADX 2.38095
48 2BIF ANP 2.38095
49 2BIF SIN 2.38095
50 4BFW ZVW 2.38095
51 3FYH ADP 2.38095
52 3EWA ANP 2.38095
53 1UPR 4IP 2.43902
54 3U6B GDP 2.97619
55 2BVN GNP 2.97619
56 3U6K GDP 2.97619
57 5W7Q GDP 2.97619
58 4LPS GDP 2.97619
59 1D8T GDP 2.97619
60 5JBQ GDP 2.97619
61 4G5G GDP 2.97619
62 1QF5 RPL 2.97619
63 1QF5 GDP 2.97619
64 4NU0 AP5 2.97619
65 2C9O ADP 2.97619
66 1CR1 TTP 2.97619
67 1DNP MHF 2.97619
68 3MWL 8OX 2.97619
69 2HCJ GDP 2.98507
70 3P4X ADP 3.1477
71 2VOH CIT 3.18471
72 2ZR9 DTP 3.57143
73 2PL3 ADP 3.57143
74 1U0J ADP 3.57143
75 3KTA AP5 3.57143
76 4YS0 ADP 3.57143
77 3QKT ANP 3.57143
78 1OS1 PYR 3.57143
79 1OS1 ATP 3.57143
80 3B2Q AES 3.57143
81 2Z5F A3P 3.57143
82 2OQ5 BEN 3.57143
83 5MVR ADP 3.7037
84 1F2U ATP 4.02685
85 2C78 GNP 4.16667
86 2C77 GNP 4.16667
87 1G7C 5GP 4.16667
88 1WDT GTP 4.16667
89 1B0U ATP 4.16667
90 1XMV ADP 4.16667
91 3FKQ ATP 4.16667
92 5BN3 ADP 4.16667
93 4WOP CTP 4.16667
94 2FSH ANP 4.16667
95 1E2K TMC 4.16667
96 1YTM ATP 4.16667
97 1Y63 ADP 4.16667
98 1L2T ATP 4.16667
99 5LJW ANP 4.16667
100 2J0W ASP 4.16667
101 5VGR GDP 4.16667
102 1XP8 AGS 4.16667
103 3BP1 GUN 4.16667
104 5NLD LBT 4.31655
105 1CBK ROI 4.375
106 4CVN ADP 4.37956
107 3WY9 GDP 4.7619
108 2WIC GNP 4.7619
109 4PPF FLC 4.7619
110 1M7G AV2 4.7619
111 1TQ4 GDP 4.7619
112 3WYA GDP 4.7619
113 5M04 GDP 4.7619
114 4E03 ADP 4.7619
115 4H1V GNP 4.7619
116 3ZS9 ADP ALF 4.7619
117 5FTB ANP 4.7619
118 2WOJ ADP ALF 4.7619
119 3VM7 GLC 4.7619
120 1G3Q ADP 4.7619
121 1M7G ADP 4.7619
122 1ION ADP 4.7619
123 1ZIN AP5 4.7619
124 5FHD ADP ALF 4.7619
125 4MKF AP5 4.7619
126 3FB4 AP5 4.7619
127 1M7G ADX 4.7619
128 1UJ2 ADP 4.7619
129 2GWH A3P 4.7619
130 1UJ2 C5P 4.7619
131 2QZ4 ADP 4.7619
132 2ZTS ADP 4.7619
133 3TMK T5A 4.7619
134 1QF9 C5P 4.7619
135 1QF9 ADP 4.7619
136 1QF9 ALF 4.7619
137 2VHJ ADP 4.7619
138 5UIV ADP 4.7619
139 4JAL SAH 4.79042
140 6B8B ADP 5.22088
141 1JJ7 ADP 5.35714
142 3MD0 GDP 5.35714
143 2D2F ADP 5.35714
144 4P4T GDP 5.35714
145 3KJI ADP 5.35714
146 1DAK ADP 5.35714
147 1DAK DPU 5.35714
148 1Z6T ADP 5.35714
149 1IN4 ADP 5.35714
150 4KBF AMP 5.35714
151 3VX3 ADP 5.35714
152 2RGX AP5 5.35714
153 4X8O AP5 5.35714
154 1F9V ADP 5.35714
155 3BFV ADP 5.35714
156 5EXT ADP 5.35714
157 5ZB0 TYD 5.35714
158 5ZB0 ADP 5.35714
159 5H4S RAM 5.35714
160 4GBM A3P 5.88235
161 3PQC GDP 5.95238
162 2WMO GTP 5.95238
163 4NON GDP 5.95238
164 4IHQ ADP 5.95238
165 4R98 GNH 5.95238
166 3TBK ANP 5.95238
167 4QOS ADP 5.95238
168 5K5Z ANP 5.95238
169 1ZUI SKM 5.95238
170 2GK6 ADP 5.95238
171 4RZ3 ADP 5.95238
172 5MEX PAP 5.95238
173 4LHD GLY 5.95238
174 2QG6 NMN 5.95238
175 4YMU ATP 5.95238
176 2AWN ADP 5.95238
177 2CDN ADP 5.97015
178 2XTZ GSP 6.54762
179 2RCN GDP 6.54762
180 1RRC ADP 6.54762
181 1XKV ATP 6.54762
182 6CS8 F9Y 6.54762
183 5NM7 GLY 6.54762
184 4MKG AP5 6.54762
185 3H4S ADP 6.54762
186 1S3G AP5 6.54762
187 4FRZ ADP 6.54762
188 1AQU A3P 6.54762
189 5G3Y ADP 6.54762
190 5WRI A3P 6.54762
191 5WRJ A3P 6.54762
192 2WJG GDP 7.14286
193 3COB ADP 7.14286
194 3A1S GDP 7.14286
195 6AU6 GDP 7.14286
196 2OG2 MLI 7.14286
197 1OXV ANP 7.14286
198 1H65 GDP 7.14286
199 1IWE IMP 7.14286
200 3DZD ADP 7.14286
201 3UIE ANP 7.14286
202 3IIJ ADP 7.14286
203 3IUY AMP 7.14286
204 5X40 ACP 7.14286
205 4QM7 GTP 7.14286
206 2WJH FLC 7.22892
207 2WJH GDP 7.22892
208 1BH2 GSP 7.7381
209 2ODE ALF GDP 7.7381
210 1SVK ALF GDP 7.7381
211 4WZ6 ATP 7.7381
212 5ZXD ATP 7.7381
213 1Y3A GDP 7.7381
214 1GP2 GDP 7.7381
215 2OM2 GDP 7.7381
216 2ZPA ADP 7.7381
217 2QEN ADP 7.7381
218 4ZDJ UTP 7.7381
219 3BFX A3P 7.7381
220 1SVM ATP 7.7381
221 1NY5 ADP 7.7381
222 3NHB ADP 7.7381
223 4NCN GTP 7.87746
224 5G3L SIA GAL 8.08081
225 5G3L SIA 8.08081
226 5KDO GDP 8.10811
227 1HFE CYS 8.13008
228 1NRJ GTP 8.22785
229 1HTW ADP 8.22785
230 5U32 GDP 8.33333
231 1JI0 ATP 8.33333
232 5XKT GNP 8.33333
233 3BOS CDP 8.33333
234 5LTJ BEF 8.33333
235 5Y6N ADP 8.33333
236 2XAU ADP 8.33333
237 2OZE AGS 8.33333
238 1OFH ADP 8.33333
239 4PJ3 ANP 8.33333
240 1G41 ADP 8.33333
241 5HR5 ADP 8.33333
242 4TL6 ANP 8.33333
243 5LTJ ADP 8.33333
244 5YT0 GDP 8.82353
245 5FG3 GDP 8.82353
246 1BG2 ADP 8.82353
247 5TSH ADP 8.82353
248 1SQ5 ADP 8.82353
249 5TSH ANP 8.82353
250 4XGU ADP 8.82353
251 4Q1A UDP 8.82353
252 4Q1A 2XZ 8.82353
253 2J5V PCA 8.82353
254 4NE2 SH2 8.82353
255 4NE2 ADP 8.82353
256 5G41 AP5 8.82353
257 1CS4 GSP 8.92857
258 5IRR GSP 8.92857
259 1LVG ADP 8.92857
260 5I0H ADP BEF 8.92857
261 5YV5 ADP 8.92857
262 1YQT ADP 8.92857
263 5HCN GCP 8.92857
264 1NJF ADP 8.92857
265 1NJF AGS 8.92857
266 4Y4V DAL 8.92857
267 5WC2 ADP 8.92857
268 2YOH WMJ 8.92857
269 4TTQ ATP 8.92857
270 3WXM GTP 9.52381
271 3AB3 GDP 9.52381
272 1ZCB GDP 9.52381
273 1G7S GDP 9.52381
274 3EZ2 ADP 9.52381
275 5H67 ATP 9.52381
276 6AIC AMP 9.52381
277 1O8B ABF 9.52381
278 3B9Q MLI 10.119
279 5GOE GDP 10.119
280 2WHX ADP 10.119
281 3B7G ANP 10.119
282 1K6M AGS 10.119
283 2NCD ADP 10.119
284 4HSE ADP 10.119
285 2JLR ANP 10.119
286 1SKQ GDP 10.7143
287 5L3R GCP 10.7143
288 2FNA ADP 10.7143
289 4XVU ATP 10.7143
290 5H68 AGS 10.7143
291 4XZ3 ACP 10.7143
292 1D2N ANP 10.7143
293 4XTR ATP 10.8108
294 4XTR ADP 10.8108
295 5KSZ GCP 11.3095
296 5VHC BEF ADP 11.3095
297 1W5T ANP 11.3095
298 1W5T ADP 11.3095
299 1Z83 AP5 11.3095
300 2WCU FUC 11.4094
301 2KIN ADP 11.7647
302 4AG5 ADP 11.7647
303 4P3Y GDP 11.7647
304 5J1J ANP 11.7647
305 4IEE AGS 11.7647
306 1FNN ADP 11.7647
307 4A4Z ANP 11.7647
308 2ZJ5 ADP 11.7647
309 3CNL GNP 11.9048
310 4KVA GTP 11.9048
311 2Q2Y ADP 11.9048
312 2Q2Y MKR 11.9048
313 6G14 G4P 12.5
314 4U00 ADP 12.5
315 1PUJ GNP 12.5
316 3Q9L ATP 12.5
317 3T34 GDP 13.0952
318 4AVV CD 13.0952
319 5Z69 AGS 13.0952
320 5KSP GDP 13.6905
321 1IHU AF3 13.6905
322 1IHU ADP 13.6905
323 1SQL GUN 13.6986
324 4PX9 ADP 14.2857
325 1GOJ ADP 14.7059
326 3ZIA ATP 14.7059
327 3ZFD ANP 14.7059
328 3ZIA ADP 14.7059
329 1W0J ADP 14.7059
330 5IFS ADP 14.7059
331 2CHG ANP 14.7059
332 2IXE ATP 14.7059
333 1W0J ADP BEF 14.7059
334 3QF7 ANP 14.7059
335 1VKJ A3P 14.7059
336 3IO3 ADP 14.7059
337 3RC3 ANP 14.7059
338 1JPA ANP 14.7059
339 3HU3 AGS 14.7059
340 5DG2 GAL GLC 14.7059
341 1R6B ADP 14.7059
342 1UKZ ADP 14.7059
343 6H5E ANP 14.7059
344 2XTN GTP 14.881
345 4PU6 ASP 14.881
346 4LYA ATP 15.4762
347 4JLV ADP 15.4762
348 5GVR LMR 15.4762
349 3H86 AP5 15.4762
350 1SVI GDP 16.0714
351 6DEF GCP 16.0714
352 2HF9 GSP 16.0714
353 4WZA ACP 16.0714
354 4WZA ADP 16.0714
355 3BER AMP 16.0714
356 1DCP HBI 16.3462
357 1WF3 GNP 16.6667
358 3E70 GDP 16.6667
359 5MZN ADP 16.6667
360 4BQS ADP 16.6667
361 4BQS K2Q 16.6667
362 2X7I CIT 17.2078
363 1VHT BA3 17.2619
364 5CK5 GDP 17.6471
365 1G6H ADP 17.6471
366 4ZG4 VO4 ADP 17.6471
367 5LB3 ADP 17.6471
368 1G6O ADP 17.6471
369 5L3S GNP 17.6471
370 2CK3 ANP 17.6471
371 2V7Q ADP 17.6471
372 2FAH GDP 17.6471
373 2CE7 ADP 17.6471
374 4YJ1 ADP 17.6471
375 6C90 ADP 17.6471
376 5L3V GDP 17.6471
377 2D7D ADP 17.6471
378 6FAA ADP 17.6471
379 1OYY AGS 17.6471
380 2WZF BGC 17.6471
381 1X6V ADP 17.6471
382 2V7Q ATP 17.6471
383 2CK3 ADP 17.6471
384 1P9B GDP 17.6471
385 3FJG 3PG 17.6471
386 5L3S G 17.6471
387 3LRE ADP 17.6471
388 4PVR ASP 17.6471
389 1NHX FTB 17.6471
390 1NHX PEP 17.6471
391 3FXU TSU 17.6471
392 2GMV UN8 17.6471
393 1T8U UAP SGN IDS SGN 17.6471
394 1QHG ATP 17.6471
395 2GMV PEP 17.6471
396 3CX8 GSP 17.8571
397 2O0J ADP 17.8571
398 5TIV A3P 17.8571
399 1P4V GLY 18.4524
400 4OI4 ATP 19.6429
401 4J0Q GDP 20.2381
402 2DPY ADP 20.2381
403 5J1S ATP 20.3252
404 1FQK ALF 20.5882
405 1TAD ALF 20.5882
406 1TAD GDP 20.5882
407 6A20 ADP 20.5882
408 1V8K ANP 20.5882
409 1FQK GDP 20.5882
410 5ZBR ANP 20.5882
411 6CRK GDP 20.5882
412 1GOT GDP 20.5882
413 1B7T ADP 20.5882
414 5BQ5 ADP BEF 20.5882
415 4OHY ANP 20.5882
416 4IDN GNP 20.5882
417 1KK8 BEF ADP 20.5882
418 6FMC DUE 20.5882
419 2ZFI ADP 20.5882
420 3DC4 ADP 20.5882
421 2Z49 AMG 20.5882
422 3FSY SCA 20.5882
423 4O48 ASP 20.5882
424 2GKS ADP 20.5882
425 1P72 ADP 20.5882
426 4IF4 BEF 20.5882
427 3VMF GTP 20.8333
428 1YXM ADE 20.8333
429 4TMZ GSP 21.4286
430 2X77 GDP 21.4286
431 2XT3 ADP 23.5294
432 1R0X ATP 23.5294
433 2IS6 ADP 23.5294
434 3ZQ6 ADP ALF 23.5294
435 4R2I ANP 23.5294
436 3FWY ADP 23.5294
437 4WEI GLC GAL 23.5294
438 5I34 GDP 23.5294
439 1NST A3P 23.5294
440 4GOX A3P 23.5294
441 4IOK ADP 23.5294
442 4IOK XPO 23.5294
443 2BO4 FLC 23.5294
444 2QQ0 ANP 23.5294
445 2QQ0 TMP 23.5294
446 2QQ0 ADP 23.5294
447 2QQ0 THM 23.5294
448 4ZI2 GNP 24.2105
449 4GOJ GNP 24.3386
450 1YRB GDP 25
451 1FZQ GDP 25.4144
452 5KUT GDP 25.5952
453 2QN6 GDP 26.4706
454 4RD0 GDP 26.4706
455 5W75 GDP 26.4706
456 1FQJ ALF 26.4706
457 4ZKD GDP 26.4706
458 5H7K GDP 26.4706
459 5H7J GCP 26.4706
460 2Y65 ADP 26.4706
461 1FQJ GDP 26.4706
462 4YDS ATP 26.4706
463 3TK1 GDP 26.4706
464 4R43 GDP 26.4706
465 5N69 ADP 26.4706
466 1APZ ASP 26.4706
467 1AKY AP5 26.4706
468 1T5C ADP 26.4706
469 1G8S MET 26.4706
470 3IT6 ORN 26.4706
471 1I0B PEL 26.4706
472 1KO8 6PG 26.4706
473 4YC7 GNP 26.7857
474 1RJ9 GCP 26.7857
475 1ZJ6 G3D 27.381
476 1DAR GDP 27.381
477 1YZG GDP 28.5714
478 3ITJ CIT 29.1667
479 4HI0 GDP 29.4118
480 5XDR ADP 29.4118
481 3RLF ANP 29.4118
482 5YLF BGC 29.4118
483 5IRN ADP 29.4118
484 1BO4 COA 29.4118
485 3FVQ ATP 29.4118
486 3WV6 GAL GLC 29.4118
487 3R7F CP 29.4118
488 1UPT GTP 30.4094
489 5DI3 GNP 30.9524
490 1R4A GNP 31.5152
491 5EE5 GTP 31.5476
492 1KSH GDP 32.1429
493 3DOE GTP 32.1429
494 1MR3 G3D 32.1429
495 1KK1 GNP 32.3529
496 5W76 GDP 32.3529
497 4KFU ACP 32.3529
498 2B8W ALF 5GP 32.3529
499 1F5N GNP 32.3529
500 1W7J ADP BEF 32.3529
501 3KAL HGS 32.3529
502 4V0K GDP 33.3333
503 2CBZ ATP 33.3333
504 3KO0 TFP 33.6634
505 3AQ4 GDP 33.9286
506 1RE0 GDP 34.1463
507 1S9D GDP 34.1463
508 4YLG GDP 35.119
509 2VVG ADP 35.2941
510 4PC3 GDP 35.2941
511 2VB6 ADP BEF 35.2941
512 4PFO ADP 35.2941
513 2J59 GTP 35.5422
514 1J2J GTP 35.5422
515 1O3Y GTP 35.5422
516 4KAX GTP 35.7143
517 2A5F GTP 35.7143
518 3PCR GTP 35.8025
519 3N5C GDP 36.4198
520 1F6B GDP 36.9048
521 2W83 GTP 36.9697
522 1M2O GNP 38.0952
523 4B47 GDP 38.0952
524 2ZEJ GDP 38.0952
525 3EC1 GDP 38.2353
526 1D2E GDP 38.2353
527 1LVK MNT BEF 38.2353
528 2QTV GNP 38.3234
529 2GJ8 ALF GDP 38.6905
530 1ZD9 GDP 38.6905
531 1M7B GTP 39.881
532 1GWN GTP 39.881
533 1MKY GDP 39.881
534 3W5J GDP 41.0714
535 2FH5 GTP 41.6667
536 4DCT GDP 43.4524
537 5UPK GNP 44.0476
538 1NF3 GNP 44.0476
539 3REF GDP 44.0476
540 1I4D GDP 45.8333
541 3SBD GNP 45.8333
542 2FJU GSP 45.8333
543 1HE1 GDP 45.8333
544 1HE1 AF3 45.8333
545 1E96 GTP 46.4286
546 1MH1 GNP 46.4286
547 2WKQ GTP 46.4286
548 2W2X GSP 46.4286
549 1DS6 GDP 46.4286
550 1G4U GDP 46.4286
551 1G4U AF3 46.4286
552 3Q85 GNP 47.0238
553 2J0V GDP 47.619
554 2GCO GNP 48.2143
555 5JCP GDP ALF 48.2143
556 1TX4 ALF GDP 48.2143
557 5IRC GDP 48.2143
558 2GCN GDP 48.2143
559 4XSH GSP 48.2143
560 1OW3 GDP 48.2143
561 5HPY GDP 48.2143
562 6BCB GSP 48.8095
563 6BCA GSP 48.8095
564 1CXZ GSP 48.8095
565 4XOI GTP 48.8095
566 1KMQ GNP 48.8095
567 3LXR GDP 48.8095
568 6BC0 GSP 48.8095
569 4U5X GNP 48.8095
570 6BSX GDP 49.4048
571 3T5G GDP 49.4048
572 6BSX E7S 49.4048
Pocket No.: 2; Query (leader) PDB : 3MJH; Ligand: GTP; Similar sites found with APoc: 31
This union binding pocket(no: 2) in the query (biounit: 3mjh.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 1M48 FRG None
2 2O66 FLC None
3 5J6Y BGC None
4 5J6Y GLC None
5 2X52 GYT None
6 1LK7 DER None
7 2JBM SRT 2.38095
8 1QAN SAH 2.38095
9 3TW1 AHN 2.97619
10 3N29 GOL 4.16667
11 4YJK URA 4.16667
12 3L8H FX1 4.7619
13 2IDV M7G 4.7619
14 4U8P UDP 5.35714
15 5DT6 GLU 5.35714
16 1N13 AG2 5.76923
17 3GDN MXN 5.95238
18 5G6U TRP 7.14286
19 5E5U MLI 8.33333
20 2OFD NGA 8.4507
21 2OFE NAG 8.4507
22 1XPJ TLA 8.73016
23 4EBZ NAG NAG NAG NAG 9.52381
24 5F7Y GLC GAL NAG GAL FUC A2G 10.8333
25 6HL7 CP 13.6905
26 5CIC 51R 14.7059
27 1TE2 PGA 14.881
28 3KC1 2T6 17.6471
29 1QHH ATP 17.6471
30 3AB4 THR 20.5882
31 3UG4 AHR 29.7619
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