Receptor
PDB id Resolution Class Description Source Keywords
3KYQ 2.44 Å EC: 2.3.1.- LIPID-INDUCED CONFORMATIONAL SWITCH CONTROLS FUSION ACTIVITY DOMAIN SNARE YKT6 RATTUS NORVEGICUS V-SNARE HOMOLOG LIPID BINDING CYTOPLASMIC VESICLE ER-GOLGTRANSPORT GOLGI APPARATUS LIPOPROTEIN PALMITATE PRENYLAPROTEIN TRANSPORT TRANSFERASE TRANSPORT
Ref.: LIPID-INDUCED CONFORMATIONAL SWITCH CONTROLS FUSION OF LONGIN DOMAIN SNARE YKT6 MOL.CELL V. 37 383 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DPV A:201;
Valid;
none;
Kd = 61 uM
351.462 C17 H38 N O4 P CCCCC...
SO4 A:199;
A:200;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3KYQ 2.44 Å EC: 2.3.1.- LIPID-INDUCED CONFORMATIONAL SWITCH CONTROLS FUSION ACTIVITY DOMAIN SNARE YKT6 RATTUS NORVEGICUS V-SNARE HOMOLOG LIPID BINDING CYTOPLASMIC VESICLE ER-GOLGTRANSPORT GOLGI APPARATUS LIPOPROTEIN PALMITATE PRENYLAPROTEIN TRANSPORT TRANSFERASE TRANSPORT
Ref.: LIPID-INDUCED CONFORMATIONAL SWITCH CONTROLS FUSION OF LONGIN DOMAIN SNARE YKT6 MOL.CELL V. 37 383 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 34 families.
1 3KYQ Kd = 61 uM DPV C17 H38 N O4 P CCCCCCCCCC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 3KYQ Kd = 61 uM DPV C17 H38 N O4 P CCCCCCCCCC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 30 families.
1 3KYQ Kd = 61 uM DPV C17 H38 N O4 P CCCCCCCCCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DPV; Similar ligands found: 10
No: Ligand ECFP6 Tc MDL keys Tc
1 DPV 1 1
2 PFS 0.539683 0.877551
3 P42 0.485294 0.826923
4 C6W 0.482143 0.847826
5 MC3 0.470588 0.877551
6 PC1 0.470588 0.877551
7 PCF 0.470588 0.877551
8 LPE 0.428571 0.826923
9 L9R 0.415584 0.86
10 POV 0.415584 0.86
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3KYQ; Ligand: DPV; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3kyq.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
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