-->
Receptor
PDB id Resolution Class Description Source Keywords
3KXC 2 Å NON-ENZYME: OTHER MUTANT TRANSPORT PROTEIN HOMO SAPIENS HETERODIMER ENDOPLASMIC RETICULUM ER-GOLGI TRANSPORT GOLGAPPARATUS LIPOPROTEIN PALMITATE TRANSPORT TRANSPORT PRO
Ref.: CHARACTERIZATION OF THE SELF-PALMITOYLATION ACTIVIT TRANSPORT PROTEIN PARTICLE COMPONENT BET3 CELL.MOL.LIFE SCI. V. 67 2653 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLM A:181;
Valid;
none;
submit data
256.424 C16 H32 O2 CCCCC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3KXC 2 Å NON-ENZYME: OTHER MUTANT TRANSPORT PROTEIN HOMO SAPIENS HETERODIMER ENDOPLASMIC RETICULUM ER-GOLGI TRANSPORT GOLGAPPARATUS LIPOPROTEIN PALMITATE TRANSPORT TRANSPORT PRO
Ref.: CHARACTERIZATION OF THE SELF-PALMITOYLATION ACTIVIT TRANSPORT PROTEIN PARTICLE COMPONENT BET3 CELL.MOL.LIFE SCI. V. 67 2653 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3KXC - PLM C16 H32 O2 CCCCCCCCCC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3KXC - PLM C16 H32 O2 CCCCCCCCCC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3KXC - PLM C16 H32 O2 CCCCCCCCCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: PLM; Similar ligands found: 62
No: Ligand ECFP6 Tc MDL keys Tc
1 MYR 1 1
2 EW8 1 1
3 TDA 1 1
4 F15 1 1
5 PLM 1 1
6 STE 1 1
7 X90 1 1
8 DAO 1 1
9 KNA 1 1
10 DCR 1 1
11 F23 1 1
12 11A 1 1
13 DKA 1 1
14 OCA 0.956522 1
15 SHV 0.833333 0.952381
16 KTC 0.793103 0.875
17 AZ1 0.73913 0.64
18 6NA 0.72 0.904762
19 ELA 0.71875 0.954545
20 OLA 0.71875 0.954545
21 NER 0.71875 0.954545
22 VCA 0.666667 0.954545
23 PAM 0.666667 0.954545
24 PML 0.625 0.6
25 3LA 0.606061 0.8
26 LEA 0.6 0.809524
27 MYZ 0.588235 0.909091
28 12H 0.586207 0.615385
29 ODD 0.567568 0.913043
30 BRC 0.566667 0.666667
31 14V 0.555556 0.740741
32 M12 0.545455 0.869565
33 14U 0.542857 0.703704
34 EIC 0.538462 0.913043
35 EOD 0.538462 0.7
36 D0G 0.5 0.954545
37 BMJ 0.5 0.954545
38 BNV 0.5 0.954545
39 BUA 0.48 0.666667
40 RCL 0.468085 0.84
41 FTT 0.459459 0.807692
42 HXD 0.459459 0.807692
43 56S 0.459459 0.653846
44 ODT 0.452381 0.782609
45 3X1 0.444444 0.818182
46 LNL 0.44186 0.826087
47 9J6 0.441176 0.666667
48 OOA 0.441176 0.76
49 CUY 0.435897 0.68
50 6UL 0.435897 0.68
51 CNS 0.435897 0.68
52 5UF 0.432432 0.807692
53 243 0.428571 0.807692
54 1QW 0.418605 0.606061
55 GYM 0.418605 0.606061
56 O8N 0.413793 0.75
57 1DO 0.413793 0.75
58 PL3 0.413793 0.75
59 OC9 0.413793 0.75
60 DE1 0.413793 0.75
61 F09 0.413793 0.75
62 T25 0.403846 0.677419
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3KXC; Ligand: PLM; Similar sites found with APoc: 221
This union binding pocket(no: 1) in the query (biounit: 3kxc.bio1) has 26 residues
No: Leader PDB Ligand Sequence Similarity
1 1ZEI CRS None
2 2GBB CIT None
3 5X80 SAL 1.25
4 3SHZ 5CO 1.89873
5 3ROE THM 2.06186
6 2WKW W22 2.06186
7 4TV1 36M 2.53165
8 4MGB XDH 2.53165
9 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 2.53165
10 5AAV GW5 2.53165
11 3UUD EST 2.53165
12 2QE4 JJ3 2.53165
13 5DXE EST 2.53165
14 4MGA 27L 2.53165
15 4MG9 27K 2.53165
16 3G58 988 2.57732
17 6EVN PRO PRO GLY PRO ALA GLY PRO PRO GLY 2.94118
18 6AYH C3G 3.09278
19 5NTP 98E 3.09278
20 6AYI C3G 3.09278
21 2HZL PYR 3.16456
22 5N53 8NB 3.16456
23 5C1M OLC 3.2
24 5C1M 4VO 3.2
25 4EKQ NPO 3.20856
26 4O4Z N2O 3.24675
27 3G4Q MCH 3.42466
28 2BJ4 OHT 3.60825
29 5FQK 6NT 3.60825
30 4AIG FLX 3.60825
31 2FP2 TSA 3.61446
32 1RL4 BL5 3.7234
33 2GWH PCI 3.79747
34 4XCP PLM 3.79747
35 2HFK E4H 3.79747
36 3G5K BB2 3.82514
37 2IYG FMN 4.03226
38 1R6N 434 4.12371
39 1XX4 BAM 4.12371
40 3V1S 0LH 4.12371
41 1NQ7 HIS LYS ILE LEU HIS ARG LEU LEU GLN GLU 4.43038
42 2QCX PF1 4.43038
43 6FFI D8B 4.43038
44 3FS1 ALA ALA LEU ALA ALA LEU LEU ALA ALA 4.63918
45 3RET SAL 4.9505
46 3RET PYR 4.9505
47 1YRX FMN 4.95868
48 3SQP 3J8 5.06329
49 2Z9I GLY ALA THR VAL 5.06329
50 1DTL BEP 5.06329
51 4W6Z ETF 5.06329
52 3WMX THR 5.06329
53 5NM7 GLY 5.06329
54 1XMY ROL 5.06329
55 4F8L GAL 5.06329
56 1XM4 PIL 5.06329
57 2WH8 II2 5.06329
58 5K52 OCD 5.06329
59 3CEV ARG 5.06329
60 1XMU ROF 5.06329
61 4RQL SNE 5.06329
62 5K53 STE 5.15464
63 4MRP GSH 5.15464
64 4RC8 STE 5.15464
65 3WYJ H78 5.15464
66 3KP6 SAL 5.29801
67 6CAY ERG 5.32544
68 2AF6 BRU 5.42636
69 1MID LAP 5.49451
70 5CX6 CDP 5.6701
71 3KYQ DPV 5.6701
72 5TV6 PML 5.6962
73 2RH1 CLR 5.6962
74 6GK6 MYR 5.6962
75 4V1F BQ1 5.81395
76 4HBM 0Y7 5.83333
77 1T0S BML 6.18557
78 1M2Z BOG 6.32911
79 3B9Z CO2 6.32911
80 5NGL NOJ BGC 6.32911
81 2OWZ CIT 6.32911
82 4DDY DN6 6.32911
83 2V95 HCY 6.32911
84 1TZD ADP 6.32911
85 6MVU K4V 6.32911
86 3BJC WAN 6.32911
87 3GN8 DEX 6.32911
88 1C1X HFA 6.47887
89 1LQY BB2 6.52174
90 5OLK DTP 6.70103
91 3SFI 3SF 6.70103
92 3NB0 G6P 6.70103
93 3TDC 0EU 6.96203
94 4M51 BEZ 6.96203
95 4FGC PQ0 6.96203
96 4OB6 S2T 6.96203
97 6C0B PAM 7.05128
98 2C1Q BTN 7.14286
99 5LX9 OLB 7.2165
100 3KU0 ADE 7.2165
101 2XN3 ID8 7.28863
102 4OAS 2SW 7.29167
103 6BMS POV 7.59494
104 1VAY AZA 7.59494
105 4EIL FOL 7.59494
106 6BYM HC3 7.59494
107 1ZPD CIT 7.73196
108 3A8H TAY 7.73196
109 4CC6 L5Y 7.73196
110 4RZB NFQ 8.22785
111 1RV1 IMZ 8.23529
112 5L7G LYS SER LEU LEU GLN GLN LEU LEU THR GLU 8.24742
113 5HCV 60R 8.24742
114 1Y4Z PCI 8.24742
115 5W7B MYR 8.51064
116 4V2O CLQ 8.53659
117 3F8C HT1 8.73016
118 5ZKC 3C0 8.76289
119 1DL2 NAG NAG BMA 8.76289
120 1NVM OXL 8.76289
121 1MFI FHC 8.77193
122 5HV0 AKG 8.86076
123 1N6B DMZ 8.86076
124 1SBR VIB 8.86076
125 1DEK DGP 8.86076
126 1N8V BDD 8.92857
127 4YMU ARG 9.27835
128 5AZC PGT 9.27835
129 4J6C STR 9.27835
130 4Q86 AMP 9.27835
131 4UCC ZKW 9.27835
132 1XVB BHL 9.49367
133 3C8E GSH 9.49367
134 5UNJ RJW 9.49367
135 3BF8 MLA 9.49367
136 3ZO7 K6H 9.57447
137 3HP9 CF1 9.79381
138 3X01 AMP 9.79381
139 4QBK 3NZ 9.79381
140 3ET1 ET1 9.79381
141 2V5E SCR 9.90099
142 2Q4G CIT 10.1266
143 4RLT FSE 10.2041
144 6A5Y 9CR 10.3093
145 3FAL REA 10.3093
146 5IM3 DTP 10.3093
147 1FM9 9CR 10.3093
148 4I90 CHT 10.3093
149 6CGN DA 10.7595
150 6FBA D48 10.7595
151 2GL0 ADN 10.7784
152 4IA6 EIC 10.8247
153 5V3Y 5V8 11.3402
154 4WGF HX2 11.3402
155 1C9K 5GP 11.3924
156 4XDY HIO 11.3924
157 4JE7 BB2 11.3924
158 4Y3O OGA 11.3924
159 1GPM CIT 11.3924
160 6ADI 9UO 11.8557
161 4ZJS 4P0 11.8557
162 4OGQ 1O2 12.0253
163 4OGQ 7PH 12.0253
164 3WQM B29 12.0253
165 4OGQ 2WD 12.0253
166 6CB2 OLC 12.0253
167 4DR9 BB2 12.0253
168 3HQ9 OXL 12.3711
169 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 12.381
170 1UUY PPI 12.5749
171 2BCG GER 12.6582
172 1I0B PEL 12.8866
173 5HCN DAO 13.0268
174 5LWY OLB 13.0841
175 3KAL HGS 13.2911
176 3V78 ET 13.2911
177 5OCA 9QZ 13.4021
178 4COL DTP 13.4021
179 3HW5 AMP 13.9241
180 1VBO MAN MAN MAN 14.094
181 3RUG DB6 14.1414
182 2Y69 CHD 14.2857
183 1HBK COA 14.6067
184 3P9T TCL 14.9485
185 6H8S FSZ 15.1899
186 4WH9 3M8 15.1899
187 5CHR 4NC 15.3285
188 3RLF MAL 15.8228
189 4YSX E23 15.8228
190 1J78 VDY 16.4948
191 3TL1 JRO 17.0886
192 3D04 SAK 17.7215
193 1ZED PNP 18.0412
194 1B4B ARG 18.3099
195 5L2R MLA 18.3544
196 4B1V LAB 18.3544
197 5XJD 87L 18.3544
198 2FDW D3G 18.5567
199 4TVD BGC 18.9873
200 1QMG DMV 19.0722
201 5Z84 CHD 19.1489
202 5ZCO CHD 19.1489
203 5W97 CHD 19.1489
204 2DYS PGV 19.1489
205 5Z84 PGV 19.1489
206 2DYR TGL 19.1489
207 2DYS TGL 19.1489
208 1SR7 MOF 19.6203
209 4BXF AKG 19.6203
210 3N7S 3N7 19.7917
211 5EY0 GTP 20.2532
212 1TV5 N8E 21.134
213 5M36 9SZ 21.519
214 2GJ3 FAD 21.6667
215 1NU4 MLA 24.7423
216 2JC9 ADN 25.3165
217 5UGW GSH 27.2152
218 4F4S EFO 27.6316
219 4ZGM 32M 29.0323
220 2GU8 796 30
221 5Y02 HBX 31.7757
APoc FAQ
Feedback