-->
Receptor
PDB id Resolution Class Description Source Keywords
3KO0 2.3 Å NON-ENZYME: OTHER STRUCTURE OF THE TFP-CA2+-BOUND ACTIVATED FORM OF THE S100A4 METASTASIS FACTOR HOMO SAPIENS MTS1 S100A4 TFP CA2+ OLIGOMERIZATION ACETYLATION CALCIBINDING PROTEIN
Ref.: PHENOTHIAZINES INHIBIT S100A4 FUNCTION BY INDUCING OLIGOMERIZATION. PROC.NATL.ACAD.SCI.USA V. 107 8605 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:301;
A:302;
B:301;
B:302;
C:301;
C:302;
D:301;
D:302;
E:301;
E:302;
F:301;
F:302;
G:301;
G:302;
H:301;
H:302;
I:301;
I:302;
J:301;
J:302;
K:301;
K:302;
L:301;
L:302;
M:301;
M:302;
N:301;
N:302;
O:301;
O:302;
P:301;
P:302;
Q:301;
Q:302;
R:301;
R:302;
S:301;
S:302;
T:301;
T:302;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
TFP A:201;
A:202;
B:201;
B:202;
C:201;
C:202;
D:201;
D:202;
E:201;
E:202;
F:201;
F:202;
G:201;
G:202;
H:201;
H:202;
I:201;
I:202;
J:201;
J:202;
K:201;
K:202;
L:201;
L:202;
M:201;
M:202;
N:201;
N:202;
O:201;
O:202;
P:201;
P:202;
Q:201;
Q:202;
R:201;
R:202;
S:201;
S:202;
T:201;
T:202;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
407.496 C21 H24 F3 N3 S CN1CC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3KO0 2.3 Å NON-ENZYME: OTHER STRUCTURE OF THE TFP-CA2+-BOUND ACTIVATED FORM OF THE S100A4 METASTASIS FACTOR HOMO SAPIENS MTS1 S100A4 TFP CA2+ OLIGOMERIZATION ACETYLATION CALCIBINDING PROTEIN
Ref.: PHENOTHIAZINES INHIBIT S100A4 FUNCTION BY INDUCING OLIGOMERIZATION. PROC.NATL.ACAD.SCI.USA V. 107 8605 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3KO0 - TFP C21 H24 F3 N3 S CN1CCN(CC1....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3KO0 - TFP C21 H24 F3 N3 S CN1CCN(CC1....
50% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3GK2 Kd = 2 mM 27A C13 H19 N5 S CN1CCN(CC1....
2 3CR4 Kd = 35 uM PNT C19 H24 N4 O2 c1cc(ccc1C....
3 5DKQ - 5D0 C25 H32 N4 O2 c1cc(ccc1C....
4 5DKN ic50 = 2222.1 uM B7I C25 H28 N4 O2 c1cc(ccc1c....
5 3LK1 Kd = 55.2 uM JKE C7 H6 O2 S c1ccc(c(c1....
6 3GK4 Kd = 120 uM 53A C18 H20 N4 O5 S CCOC(=O)C1....
7 5DKR ic50 = 66.6 uM 5CZ C22 H19 N5 O [H]/N=C(c1....
8 3HCM - S45 C13 H14 Cl N3 O c1cc(ccc1c....
9 3LK0 Kd = 696.9 uM Z80 C17 H19 Cl N2 S CN(C)CCCN1....
10 3CR5 Kd = 64 uM PNT C19 H24 N4 O2 c1cc(ccc1C....
11 3GK1 Kd = 80 uM 32A C13 H17 N3 O2 S CCCCC#Cc1c....
12 3KO0 - TFP C21 H24 F3 N3 S CN1CCN(CC1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: TFP; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 TFP 1 1
2 Z80 0.409639 0.796296
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 141
This union binding pocket(no: 1) in the query (biounit: 3ko0.bio6) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 2EVL GAL SPH EIC None
2 4MSG 2C6 None
3 1N8V BDD None
4 1GZ6 NAI None
5 2CFC NAD None
6 5MW4 5JU None
7 3FRQ ERY None
8 4BAE RWX None
9 4IRX INS None
10 4JAL SAH None
11 6CS8 F9Y None
12 5H5O PCG None
13 1BRW URA 1.9802
14 1N83 CLR 1.9802
15 3JQF NAP 1.9802
16 3JQ8 NAP 1.9802
17 3BMQ NAP 1.9802
18 1DEK DGP 2.9703
19 4NVQ 2OD 2.9703
20 4NVQ SAH 2.9703
21 3RDE OYP 2.9703
22 2DM6 NAP 2.9703
23 3AHQ FAD 3.9604
24 1NP7 FAD 3.9604
25 3NRR UMP 3.9604
26 3D78 NBB 3.9604
27 2ZBA ZBA 4.9505
28 5L0S UDP 4.9505
29 1FCZ 156 4.9505
30 2HI4 BHF 4.9505
31 2XN5 FUN 4.9505
32 5GSN FAD 4.9505
33 2AZC 3TL 5.05051
34 6GL8 F3Q 5.94059
35 1YZQ GNP 5.94059
36 4BNU 9KQ 5.94059
37 3WUC GLC GAL 5.94059
38 2HFK E4H 5.94059
39 4NBT NAD 5.94059
40 5MPT SAH 5.94059
41 4IID NOJ 5.94059
42 6FE1 V14 5.94059
43 5O0B 9FE 6.93069
44 4EFH ADP 6.93069
45 4B1W ATP 7.92079
46 2PBD ATP 7.92079
47 4B1V LAB 7.92079
48 4B1V ATP 7.92079
49 3SJH ATP 7.92079
50 2V51 ATP 7.92079
51 5YEE ATP 7.92079
52 3C1M ANP 7.92079
53 1SQK ADP 7.92079
54 5ZZB ATP 7.92079
55 5X3R 7Y3 7.92079
56 5YPU ATP 7.92079
57 3SJH LAR 7.92079
58 4B1X ATP 7.92079
59 1Z2I NAD 7.92079
60 4L1F FAD 7.92079
61 4H03 LAR 7.92079
62 3VSV XYP 7.92079
63 3U9Z ADP 7.92079
64 1R37 NAD 7.92079
65 6FBA D48 7.92079
66 3U2U UDP 7.92079
67 3RZ3 U94 7.92079
68 4P3H 25G 7.92079
69 4RLQ 3SK 7.92079
70 5XK9 GST 8.91089
71 5XK9 DMA 8.91089
72 3CIP ATP 8.91089
73 4CBU ATP 8.91089
74 1YAG ATP 8.91089
75 4Z94 ATP 8.91089
76 4NAT ADP 8.91089
77 4NAT 2W5 8.91089
78 3L4S NAD 8.91089
79 4UCF GLA 8.91089
80 4PKG ATP 8.91089
81 4PKI ATP 8.91089
82 1HBK MYR 8.98876
83 3E2M E2M 9.90099
84 1W85 TDP 9.90099
85 2A3Z ATP 9.90099
86 3MN5 ATP 9.90099
87 2D1K ATP 9.90099
88 2A40 ATP 9.90099
89 2A42 ATP 9.90099
90 1N9G NAP 9.90099
91 1W0O DAN 9.90099
92 6ADI 9UO 11.8812
93 2VPR TDC 11.8812
94 3NRZ FAD 12.8713
95 3BZ3 YAM 12.8713
96 3MN7 ATP 13.8614
97 3MN6 ATP 13.8614
98 3MN9 ATP 13.8614
99 1LLF F23 13.8614
100 1OT6 HC4 13.8614
101 5N5U 7N8 13.8614
102 2DYR PGV 14.8936
103 5ZCO PGV 14.8936
104 2DYS PGV 14.8936
105 5Z84 PGV 14.8936
106 2DYS TGL 14.8936
107 2DYR TGL 14.8936
108 5ZCO PSC 14.8936
109 5ZCO TGL 14.8936
110 1B7H LYS NLE LYS 16.8317
111 2J0W ADP 16.8317
112 5I60 67W 16.8317
113 1RDT L79 16.8317
114 1HKK NAA NAA AMI 16.8317
115 4CBX ATP 17.8218
116 4J56 FAD 18.8119
117 2Z6D FMN 18.8119
118 1GR0 NAD 18.8119
119 6D5H FV7 19.802
120 6D56 FVM 19.802
121 6D5G FVD 19.802
122 6D59 FVJ 19.802
123 6D55 FWA 19.802
124 1Z0J GTP 19.802
125 4PL8 ATP 20.5479
126 4LSJ LSJ 20.7921
127 5WP4 SAH 20.7921
128 2WKQ FMN 20.7921
129 5AEW BNL 21.7822
130 1SR7 MOF 23.7624
131 5KVM THR TYR PHE ALA VAL LEU MET VAL SER 24.7525
132 5UY8 8UM 24.7525
133 3CGD FAD 25.7426
134 3CGD COA 25.7426
135 3CGD NAD 25.7426
136 2A2C ADP 25.7426
137 2A2C NG1 25.7426
138 4E2J MOF 26.7327
139 4WQ2 3SU 28.7129
140 3QKD HI0 29.703
141 1KXP ATP 33.6634
Pocket No.: 2; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 149
This union binding pocket(no: 2) in the query (biounit: 3ko0.bio6) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 1RM8 BAT None
2 5UGW GSH None
3 2B4D COA None
4 2NPA MMB None
5 6G96 ACO None
6 1ZVX FIN None
7 1HFS L04 None
8 3OLL EST None
9 4QIJ 1HA None
10 4UNR QZE None
11 1ZEI CRS None
12 3GEG NAD None
13 1ATL 0QI None
14 1AWI PRO PRO PRO PRO PRO PRO PRO PRO PRO PRO None
15 3STD MQ0 None
16 3G08 FEE None
17 1KUK PCA LYS TRP None
18 4ORR PE3 None
19 1RL4 BRR None
20 1Q1Y BB2 None
21 6ALW BMJ None
22 4JE7 BB2 None
23 2W14 WR2 None
24 5T70 THR SER ASN LEU GLN GLU GLN ILE GLY TRP None
25 1NYT NAP None
26 2FV5 541 None
27 5U98 VAL THR THR ASP ILE GLN VAL LYS VAL None
28 2YJD YJD None
29 2CJF RP4 None
30 1BKC INN None
31 3SP6 IL2 None
32 1G27 BB1 None
33 2GJ3 FAD None
34 4UA3 COA None
35 1K7L 544 None
36 2ZFU SAH None
37 1OD6 PNS None
38 1MMQ RRS 1.9802
39 3M6P BB2 1.9802
40 2FAV APR 1.9802
41 6AYI C3G 1.9802
42 1R55 097 1.9802
43 5UWA 8ND 2.9703
44 5YWX 93C 2.9703
45 5YWX GSH 2.9703
46 2JBZ COA 2.9703
47 2Z7I 742 2.9703
48 1RSD PSB 2.9703
49 3ND6 ATP 3.9604
50 3OKI OKI 3.9604
51 3FZG SAM 3.9604
52 5VN0 NAI 3.9604
53 4P5Z Q7M 3.9604
54 5KF9 ACO 3.9604
55 1S17 GNR 3.9604
56 5G3N X28 3.9604
57 3HB5 E2B 4.9505
58 4KX8 L2O VAL VAL ASP 4.9505
59 1SO2 666 4.9505
60 2E2R 2OH 4.9505
61 3G4Q MCH 4.9505
62 2LBD REA 4.9505
63 5N87 N66 4.9505
64 5WL1 CUY 4.9505
65 1DLL LAT 4.9505
66 4UUG PXG 4.9505
67 1JNR FAD 5.94059
68 5OBY ANP 5.94059
69 3OU2 SAH 5.94059
70 5OBU ANP 5.94059
71 2VBA P4T 5.94059
72 4QJR PIZ 5.94059
73 1ECM TSA 5.94059
74 1PZO CBT 5.94059
75 3Q2H QHF 5.94059
76 5Y77 KYN 5.94059
77 3JZB 4HY 5.94059
78 3UP3 XCA 5.94059
79 1ZDT PEF 5.94059
80 5LWY OLB 5.94059
81 1YP0 PEF 5.94059
82 2ZPA ACO 5.94059
83 2GCE SFC 6.93069
84 3QWI CUE 6.93069
85 4YSX EPH 6.93069
86 4QGE 35O 6.93069
87 2HFN FMN 6.93069
88 4V24 GYR 6.93069
89 6GWR FEW 6.93069
90 1XON PIL 6.93069
91 3OJI PYV 6.93069
92 1VLH PNS 6.93069
93 3HP9 CF1 6.93069
94 1LRI CLR 7.14286
95 2V7Y ADP 7.92079
96 4WZV E40 7.92079
97 5YJF 8WO 7.92079
98 5ISZ GLY ILE LEU GLY PHE VAL PHE THR LEU 7.92079
99 3TGE TGE 7.92079
100 5YJF SAH 7.92079
101 2J83 BAT 7.92079
102 2A8X FAD 8.91089
103 3DST GRG 8.91089
104 4E90 7RG 8.91089
105 5HM3 649 8.91089
106 2QG6 NMN 8.91089
107 6GXA TB8 8.91089
108 4GAA BES 8.91089
109 5DEY 59T 8.91089
110 3G5K BB2 8.91089
111 2FB3 GTP 8.91089
112 1TXR BES 9.90099
113 3ZKK XYP XYP XYP XYP 9.90099
114 5JZI LYS LEU VAL ALA LEU GLY ILE ASN ALA VAL 9.90099
115 5EXW 7DT 9.90099
116 4DD8 BAT 9.90099
117 2GTE VA 9.90099
118 2AEL SAZ 9.90099
119 2HFP NSI 9.90099
120 5FUS DAO 9.90099
121 3TMK T5A 11.8812
122 5HCV 60R 11.8812
123 1BII ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 11.8812
124 3EWK FAD 12.8713
125 2TCL RO4 12.8713
126 5C2H 4XU 12.8713
127 6BJ3 ILE PRO LEU THR GLU GLU ALA GLU LEU 12.8713
128 4XCP PLM 12.8713
129 5JF2 SF7 13.8614
130 4JNE ATP 14.8515
131 4AR8 IP8 GLY PRO ALA 14.8515
132 4ELG 52I 14.8515
133 4ELG 52J 14.8515
134 3WV1 WHH 15.8416
135 1M48 FRG 16.5414
136 1Q3A NGH 16.8317
137 1FBL HTA 18.8119
138 5EHR 5OD 18.8119
139 3G4G D71 19.802
140 4J36 1HR 20.7921
141 4J36 FAD 20.7921
142 3CX5 SMA 20.7921
143 5E1M SAH 20.7921
144 5E1M PRO PRO LYS ARG ILE ALA 20.7921
145 4B9Q ATP 21.7822
146 1SVM ATP 23.7624
147 5MWY YNU 23.7624
148 5V03 658 26.7327
149 5UFS 1TA 26.7327
Pocket No.: 3; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 36
This union binding pocket(no: 3) in the query (biounit: 3ko0.bio6) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4ITU 1HS None
2 1ZBQ NAD None
3 4DK7 0KS None
4 4XTX 590 None
5 5AZC PGT None
6 4S15 4D8 1.9802
7 3BMN NAP 1.9802
8 5TWJ SAM 1.9802
9 3LN0 52B 2.9703
10 1F8Y 5MD 2.9703
11 3A23 GAL 2.9703
12 4R84 CSF 4.9505
13 4X8O AP5 5.94059
14 5QB1 F1C 5.94059
15 5W10 CMP 5.94059
16 1WDK N8E 5.94059
17 5JU6 BGC 5.94059
18 3NTA COA 5.94059
19 5K0S 0OU 5.94059
20 1H5Q NAP 6.93069
21 3SFI 3SF 6.93069
22 4KCF FMN 6.93069
23 3HCN CHD 7.92079
24 2RAB FAD 7.92079
25 2Q4H AMP 8.91089
26 2BJU IH4 9.90099
27 4P6X HCY 9.90099
28 4C2V YJA 9.90099
29 2A3I C0R 11.8812
30 4D7M TDC 11.8812
31 5L13 6ZE 12.8713
32 6ARJ SAH 12.8713
33 6ARJ BW4 12.8713
34 1RC0 KT5 13.8614
35 4YRY FAD 15.8416
36 5G5W R8C 20.7921
Pocket No.: 4; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 242
This union binding pocket(no: 4) in the query (biounit: 3ko0.bio6) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 6ALW BNV None
2 2OKL BB2 None
3 2VBQ BSJ None
4 5MT9 SRO None
5 5MT9 ARG None
6 3KDU NKS None
7 4AIG FLX None
8 4B6C B5U None
9 5BQI 4UL None
10 5BQI GSH None
11 4OHU 2TK None
12 4OHU NAD None
13 1LQY BB2 None
14 1HG4 LPP None
15 2I0G I0G None
16 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU None
17 3R1V AZB None
18 4C2X NHW None
19 3D04 SAK None
20 3FEI CTM None
21 1UVC STE None
22 2JEV NHQ None
23 1NU4 MLA None
24 3ET1 ET1 None
25 6B5K TYD None
26 3GWL FAD None
27 6GH1 ARG LEU PRO ALA LYS ALA PRO LEU LEU None
28 3DFR MTX None
29 1YBU APC None
30 4V2O CLQ None
31 5CHR 4NC None
32 2J1P GRG None
33 4WKI 3PW None
34 1C1X HFA None
35 2GBB CIT None
36 3IA4 MTX None
37 3NBK PNS None
38 3JRS A8S None
39 1BW9 PPY None
40 4HBM 0Y7 None
41 1YOK P6L 1.9802
42 1YUC EPH 1.9802
43 1ZDU P3A 1.9802
44 5UNJ RJW 1.9802
45 3ETG GLU 1.9802
46 3ETG NDP 1.9802
47 3ETG GTP 1.9802
48 3QLM PLM 1.9802
49 3EKK GS2 1.9802
50 5DUF G7A 2.9703
51 5AAV GW5 2.9703
52 2BJ4 OHT 2.9703
53 4IA6 EIC 2.9703
54 4TV1 36M 2.9703
55 2QE4 JJ3 2.9703
56 4MGB XDH 2.9703
57 1UOU CMU 2.9703
58 2PD4 NAD 2.9703
59 2PD4 DCN 2.9703
60 4LAE NAP 2.9703
61 4LAE 1VM 2.9703
62 1SBR VIB 2.9703
63 2YPO PHE 2.9703
64 5EPL 5R0 PHE ALA LEU ELY 5R5 3.33333
65 3P0K FAD 3.9604
66 4WP9 ZDA 3.9604
67 5NTP 98E 3.9604
68 5NTW 98N 3.9604
69 6ESN BWE 3.9604
70 3G5N PB2 3.9604
71 5IXK 6EW 3.9604
72 5NI5 8YB 3.9604
73 5APK 76E 3.9604
74 6F7L CWH 3.9604
75 4WPF 3SN 3.9604
76 2O3Z AI7 3.9604
77 4OIV XX9 3.9604
78 6F6E PLM 3.9604
79 2WH8 II2 3.9604
80 1YKD CMP 4.27136
81 3QCP FAD 4.9505
82 1R5L VIV 4.9505
83 1KZN CBN 4.9505
84 5WIU AQD 4.9505
85 6C7D EOJ 4.9505
86 4BXK 1IU 4.9505
87 3TKY SAH 4.9505
88 4M73 SAH 4.9505
89 4M73 M72 4.9505
90 5OYH T99 4.9505
91 4CA5 3EF 5.94059
92 1YMT DR9 5.94059
93 4EOX 0S5 5.94059
94 1P3D ANP 5.94059
95 3WCA FPS 5.94059
96 4DR9 BB2 5.94059
97 4WVO 3UZ 5.94059
98 3TDC 0EU 5.94059
99 4LA7 A1O 5.94059
100 5EQY 5RA 5.94059
101 5ICE 2H4 5.94059
102 5LX9 OLB 5.94059
103 3KDJ A8S 5.94059
104 4QWT ACD 5.94059
105 4KVL PLM 5.94059
106 5Z1N PEF 5.94059
107 1FCH TYR GLN SER LYS LEU 5.94059
108 2E7Z MGD 5.94059
109 2JJK R15 5.94059
110 1GQY ACP 6.93069
111 6C1R EFD 6.93069
112 4WZ8 3W7 6.93069
113 1UDY CS8 6.93069
114 5JO1 6LM 6.93069
115 1UDY FAD 6.93069
116 1AOE NDP 6.93069
117 1AOE GW3 6.93069
118 2O5L MNR 6.93069
119 3GWT 066 6.93069
120 4DV8 0LX 6.93069
121 1XM4 PIL 6.93069
122 4DS8 A8S 6.93069
123 2WG9 OCA 6.93069
124 2OI9 GLN LEU SER PRO PHE PRO PHE ASP LEU 6.93069
125 1XMU ROF 6.93069
126 2Q2Y MKR 6.93069
127 2Q2Y ADP 6.93069
128 1XMY ROL 6.93069
129 2FR3 REA 6.93069
130 2EW5 Y12 6.93069
131 3C9U ADP 6.93069
132 5V13 JH3 6.93069
133 4NKW PLO 6.93069
134 4F7E 0SH 7.92079
135 3QUZ QUV 7.92079
136 4C12 ADP 7.92079
137 2YNC YNC 7.92079
138 2YNE NHW 7.92079
139 2YNE YNE 7.92079
140 3QP4 HL0 7.92079
141 5OLZ T4E 7.92079
142 5TO8 7FM 7.92079
143 3SCM LGN 7.92079
144 4M7V RAR 7.92079
145 4JD3 PLM 7.92079
146 4JD3 COA 7.92079
147 4EI7 GDP 7.92079
148 2ZXG S23 8.91089
149 5B4B LP5 8.91089
150 3P9T TCL 8.91089
151 3ET3 ET1 9.90099
152 2PRG BRL 9.90099
153 2R0N TGC 9.90099
154 1RX0 2MC 9.90099
155 2EIX FAD 9.90099
156 3G58 988 9.90099
157 5AHS COA 9.90099
158 2VJ8 HA2 9.90099
159 2P4Y C03 9.90099
160 4P6W MOF 9.90099
161 1N1G BCP 9.90099
162 5W8Q BU4 9.90099
163 3B1M KRC 9.90099
164 5G57 6M5 10.8911
165 4OGQ 2WA 10.8911
166 3V49 PK0 10.8911
167 2AX9 BHM 10.8911
168 4NE2 SH2 10.8911
169 2BW7 APC 10.8911
170 2BW7 ECS 10.8911
171 4GFD 0YB 10.8911
172 1ZGA HMK 10.8911
173 5N9T 8QQ 10.8911
174 3KMZ EQO 10.8911
175 3KMR EQN 10.8911
176 4NE2 ADP 10.8911
177 3IQE F42 10.8911
178 4OGQ 3WM 10.8911
179 3IQE H4M 10.8911
180 4UWJ MYA 11.8812
181 4UWJ 7L5 11.8812
182 2WCJ M21 11.8812
183 2H7C COA 11.8812
184 2X24 X24 11.8812
185 2YB9 HA0 11.8812
186 1BGQ RDC 11.8812
187 3BEJ MUF 12
188 4DM8 REA 12
189 5C2H 4PX 12.8713
190 3HR1 PF9 12.8713
191 4ZVV NAD 12.8713
192 1EYQ NAR 12.8713
193 4ZVV GN0 12.8713
194 2F99 AKV 12.8713
195 1TYU GLA MAN RAM TYV GLA MAN RAM TYV 13.8614
196 1AL8 DHP 13.8614
197 4LY9 1YY 13.8614
198 4LY9 S6P 13.8614
199 4R57 ACO 13.8614
200 2XCG XCG 14.8515
201 1XVB BHL 14.8515
202 6CC0 EWM 14.8515
203 1KPG 16A 14.8515
204 2DYR PEK 14.8936
205 2DYS PEK 14.8936
206 5Z84 PSC 14.8936
207 5Z84 TGL 14.8936
208 5ZCO PEK 14.8936
209 1OLM VTQ 16.8317
210 4I6G FAD 16.8317
211 4ZVI 4S4 16.8317
212 1DKF OLA 16.8317
213 1CZR FMN 16.8317
214 1FM9 570 16.8317
215 1FM9 9CR 16.8317
216 4M8E 29V 16.8317
217 3HYW DCQ 16.8317
218 3ROE THM 17.8218
219 3RO7 TDR 17.8218
220 3UA1 08Y 17.8218
221 3WYJ H78 18.8119
222 5CJH 522 18.8119
223 2R40 EPH 18.8119
224 3NMV PYV 18.8119
225 2X5W K2B 18.8119
226 5OHJ 9VE 19.802
227 5EK3 5PK 19.802
228 1WS1 BB2 19.802
229 3BQD DAY 20.7921
230 1NHZ 486 20.7921
231 1M2Z DEX 20.7921
232 4DHY S41 20.7921
233 1EZV SMA 20.7921
234 2QXL ATP 20.7921
235 4LPG 1MV 21.7822
236 2JC9 ADN 21.7822
237 6MPT C30 22.7723
238 4OAR 2S0 23.7624
239 5UC1 486 23.7624
240 1T8U UAP SGN IDS SGN 25.7426
241 3GN8 DEX 26.7327
242 2Q1H AS4 28.7129
Pocket No.: 5; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 23
This union binding pocket(no: 5) in the query (biounit: 3ko0.bio3) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4ITU NAI None
2 1Q5D EPB 1.9802
3 2UZI GTP 1.9802
4 2VDY HCY 2.9703
5 3F3E LEU 4.9505
6 6FP4 FAD 4.9505
7 5FB3 NDP 4.9505
8 1NJF AGS 4.9505
9 1J0X NAD 5.94059
10 1E8G FAD 6.93069
11 1E8G FCR 6.93069
12 5O2T GSP 6.93069
13 3U4L ATP 6.93069
14 4H03 ATP 7.92079
15 4ZL4 4PK 7.92079
16 2FXV 5GP 7.92079
17 5ISY NAD 10.8911
18 1TT8 PHB 12.8713
19 4YRY NAD 15.8416
20 1DUV PSQ 17.8218
21 6D55 GNP 19.802
22 5L7G 6QE 23.7624
23 4UDB CV7 23.7624
Pocket No.: 6; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 33
This union binding pocket(no: 6) in the query (biounit: 3ko0.bio3) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 4XDA RIB None
2 4XDA ADP None
3 1B63 ANP None
4 2PX6 DH9 None
5 3R35 4CO None
6 1L6O SER LEU LYS LEU MET THR THR VAL None
7 6F68 GSH None
8 4MZQ 1VU None
9 3KFC 61X None
10 4MG8 27J 2.9703
11 2WPF FAD 4.9505
12 6FX0 E9T 4.9505
13 3BY9 SIN 4.9505
14 4QOS ADP 5.94059
15 2MBR FAD 5.94059
16 2MBR EPU 5.94059
17 4X6F 3XU 5.94059
18 1NY5 ADP 5.94059
19 5B4T 3HR 6.93069
20 5B4T NAD 6.93069
21 4WQM FAD 6.93069
22 3WH1 NAG NAG NAG NAG 6.93069
23 5FWA J7C 7.92079
24 1IG0 VIB 7.92079
25 3B99 U51 7.92079
26 5C0C ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA 8.91089
27 2Q8M AMP 8.91089
28 6AD9 KK4 9.90099
29 5TIV A3P 12.8713
30 1MUU NAD 19.802
31 5B25 4QJ 21.7822
32 1MWH GTG 22.7723
33 1CMC SAM 24.7525
Pocket No.: 7; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 26
This union binding pocket(no: 7) in the query (biounit: 3ko0.bio3) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 2IYG FMN None
2 1YRX FMN None
3 4XXH T6P None
4 3JQ9 NAP 1.9802
5 5FTW SAH 2.9703
6 1G16 GDP 3.9604
7 4B2Z P5S 3.9604
8 1ODM ASV 5.94059
9 2D1S SLU 5.94059
10 1XKD NAP 6.93069
11 2PAV ATP 7.92079
12 2Q97 ATP 7.92079
13 3AB1 FAD 7.92079
14 2D4V NAD 7.92079
15 3WDM ADN 8.91089
16 3L4S 3PG 8.91089
17 4Z9D NAD 10.8911
18 4OCJ NDG 13.8614
19 5Y24 GLY MET PRO ARG GLY ALA 13.8614
20 2V92 ATP 15.8416
21 5MBC FMN 15.8416
22 5HTX ADP 15.8416
23 3NJ4 AFX 16.8317
24 5HRA DAS 18.8119
25 1HV9 UD1 28.7129
26 5AE9 OKO 29.703
Pocket No.: 8; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 50
This union binding pocket(no: 8) in the query (biounit: 3ko0.bio3) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 5U98 1KX None
2 3GWN FAD None
3 4OAS 2SW None
4 5XWC NAP None
5 5XWC 8GL None
6 5XWC 2IT None
7 3LLI FAD None
8 2RFX LEU SER SER PRO VAL THR LYS SER PHE None
9 2VVT I24 1.9802
10 4TUZ 36J 2.9703
11 5G4L NDP 2.9703
12 4MGD 27N 2.9703
13 4MG7 27H 2.9703
14 1X0P FAD 2.9703
15 2IHU TP9 2.9703
16 3V1S 0LH 2.9703
17 3H78 BE2 3.9604
18 5WL1 D3D 4.9505
19 3KB9 BTM 4.9505
20 5UI2 EQ3 4.9505
21 5C1M OLC 4.9505
22 3IU9 T07 5.94059
23 1C9K 5GP 5.94059
24 5VZ0 2BA 5.94059
25 4ORM FMN 6.93069
26 4ORM 2V6 6.93069
27 4ORM ORO 6.93069
28 1JDC GLC GLC GLC GLC 6.93069
29 1LPD ADE 7.92079
30 4IAE 1DX 8.91089
31 2HJ3 FAD 8.91089
32 5JE8 NAD 8.91089
33 2BUP ATP 9.90099
34 2BUP ADP 9.90099
35 5K13 6Q7 10.8911
36 2QWO ADP 11.9565
37 4ZAC 4LU 12.8713
38 4GA6 AMP 12.8713
39 1YP1 LYS ASN LEU 14.8515
40 3FAL LO2 16.8317
41 4EKQ NPO 18.8119
42 2R40 20E 18.8119
43 2NPX NAD 19.802
44 5AR0 GB8 20.7921
45 6G3R ADP 20.7921
46 2R75 01G 21.7822
47 5DX0 SFG 25
48 5I7S NAD 28.7129
49 5I7S E9P 28.7129
50 6APV 3L4 34.6535
Pocket No.: 9; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 61
This union binding pocket(no: 9) in the query (biounit: 3ko0.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5FVJ ACO None
2 2IVD ACJ None
3 3VRV YSD None
4 1AG9 FMN None
5 1YKI FMN None
6 1YKI NFZ None
7 6AYH C3G None
8 3RET SAL None
9 3RET PYR None
10 3ZCB ATP None
11 4D42 NAP 1.9802
12 4D42 W0I 1.9802
13 4OOP DUP 1.9802
14 3WR7 COA 1.9802
15 1UPA TPP 2.9703
16 2XSU PIE 3.9604
17 2CDU ADP 3.9604
18 3OKP GDD 3.9604
19 1MGP PLM 3.9604
20 3OKA GDD 3.9604
21 1LVK MNT BEF 4.9505
22 5LOF 70R 4.9505
23 4KIB SAH 4.9505
24 3V66 D3A 5.94059
25 2ZCQ B65 5.94059
26 2VTD LKM 5.94059
27 4PTZ FMN 5.94059
28 3IIS PID 6.93069
29 2GMH UQ5 6.93069
30 4Y30 49L 6.93069
31 4Y30 SAH 6.93069
32 1PZG A3D 6.93069
33 4Z2B 4LC 6.93069
34 3RGA ILD 6.93069
35 3K5I AIR 7.92079
36 5A8E XTK 7.92079
37 5UQK U2F 7.92079
38 2GQT FAD 8.91089
39 4AVB ACO 8.91089
40 3G9E RO7 9.90099
41 3OZ2 FAD 9.90099
42 4OYA 1VE 9.90099
43 5TWO 7MV 9.90099
44 3OZ2 OZ2 9.90099
45 6BTN E8M 9.90099
46 2BCG GER 9.90099
47 5F1R 42O 9.90099
48 3RWP ABQ 10.8911
49 3T58 FAD 11.8812
50 4WO4 JLS 12.8713
51 3GZ9 D32 13.8614
52 5EEH SAH 13.8614
53 5EEH P9P 13.8614
54 1XVB 3BR 14.8515
55 4H07 IPH 15.8416
56 1DKF BMS 16.8317
57 4POJ 2VP 16.8317
58 2YOO K2B 18.8119
59 2E9L PLM 21.7822
60 3C88 ARG ARG GLY CYS NH2 22.7723
61 3GD4 NAD 28.7129
Pocket No.: 10; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 28
This union binding pocket(no: 10) in the query (biounit: 3ko0.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 3IUY AMP None
2 4PL9 ADP None
3 3BGD PM6 None
4 4YGF AZM 1.9802
5 4EDF UPG 2.9703
6 3QXY SAM 3.9604
7 3OBK PBG 3.9604
8 2XN3 ID8 4.9505
9 3KRL KRL 5.94059
10 2F59 INI 6.93069
11 5XLX SAH 6.93069
12 5H62 UDP 6.93069
13 2FXU ATP 7.92079
14 1B8O IMH 7.92079
15 4R6W SAH 7.92079
16 1PVN MZP 7.92079
17 5ETJ IM5 7.92079
18 1N62 FAD 10.8911
19 6F9Q NAD 10.8911
20 5SYM 71Q 10.8911
21 1RHC F42 ACN 12.8713
22 3RK0 AMP 13.8614
23 3NJ4 NAD 16.8317
24 1T36 U 17.8218
25 1A59 COA 24.7525
26 5UY8 AMZ 24.7525
27 2RG0 CTT 29.703
28 2RFZ CTR 29.703
Pocket No.: 11; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 61
This union binding pocket(no: 11) in the query (biounit: 3ko0.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5O42 9JW None
2 5O42 BGC None
3 5O42 NAD None
4 2ZFZ ARG None
5 5W7U GY8 None
6 5UR6 8KM None
7 5N7O 69Y None
8 2F7A BEZ None
9 1GHE ACO None
10 4OGN 2U5 None
11 3ZLM ANP None
12 1LBT T80 1.9802
13 3E3U NVC 1.9802
14 3MPI GRA 2.9703
15 6AP8 BNY 2.9703
16 3B9Z CO2 2.9703
17 2IHT TPP 2.9703
18 1IID NHM 3.9604
19 2WSA 646 3.9604
20 2WSA MYA 3.9604
21 5YS9 FAD 3.9604
22 1VPV PLM 3.9604
23 2WPF WPF 4.9505
24 6CGN DA 4.9505
25 5C1M 4VO 4.9505
26 1OBV FMN 4.9505
27 1IYK MYA 5.94059
28 4U0S ADP 5.94059
29 1XUJ BOZ 5.94059
30 5K7K 6RJ 6.93069
31 2WKW W22 6.93069
32 3TL1 JRO 6.93069
33 2FXU BID 7.92079
34 5EY0 GTP 7.92079
35 3RUG DB6 7.92079
36 2EV1 OLA 7.92079
37 1GUX ASP LEU TYR CYS TYR GLU GLN LEU ASN 7.92079
38 2BIF BOG 7.92079
39 3V78 ET 7.92079
40 2P1C GG3 7.92079
41 2RH1 CAU 7.92079
42 4M52 FAD 8.91089
43 2WPX ACO 8.91089
44 6BQC LOP 9.90099
45 1TMX HGX 9.90099
46 5UIJ TYD 10.8911
47 2Z9I GLY ALA THR VAL 10.8911
48 3SQP 3J8 10.8911
49 2PEH LYS ARG LYS SER ARG TRP ASP GLU THR PRO 12.8713
50 5SWB NAG BMA MAN MAN MAN MAN 13.8614
51 2Y69 CHD 14.8515
52 5ZCO CHD 14.8936
53 5Z84 CHD 14.8936
54 5W97 CHD 14.8936
55 3FAL REA 16.8317
56 2VL8 UDP 16.8317
57 1OPK P16 18.8119
58 2IBZ UQ6 20.7921
59 1JQI CAA 21.7822
60 5H94 LYS MET ASN THR GLN PHE THR ALA VAL 22.7723
61 1BUC CAA 25.7426
Pocket No.: 12; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 18
This union binding pocket(no: 12) in the query (biounit: 3ko0.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 1LLU NAD 1.9802
2 6ECT SAM 3.9604
3 1A27 NAP 4.9505
4 3S43 478 5.05051
5 2X41 BGC 5.94059
6 1MS9 LAT 5.94059
7 2NSX IFM 7.92079
8 1US5 GLU 7.92079
9 4PNE SAH 8.91089
10 4WAS NAP 9.90099
11 5X8G S0N 12.8713
12 1ZPD DPX 12.8713
13 5N5U AMP 13.8614
14 4QDF 30Q 14.8515
15 3B8Y ADA ADA ADA ADA 14.8515
16 2Y8L AMP 15.8416
17 2Y8L ADP 15.8416
18 6ECU SAH 30.6931
Pocket No.: 13; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 5
This union binding pocket(no: 13) in the query (biounit: 3ko0.bio8) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4GKV NAD None
2 3NRR D16 3.9604
3 6MVU K4V 6.93069
4 1W3Y PVC 9.90099
5 5XCZ GLC BGC 12.8713
Pocket No.: 14; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 16
This union binding pocket(no: 14) in the query (biounit: 3ko0.bio8) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4KOT CE3 None
2 3CB2 GDP None
3 2B4B COA None
4 4B7H NDP None
5 2ZW5 COA 1.9802
6 6D6L FY4 3.9604
7 2D3M COA 5.94059
8 1YBH FAD 5.94059
9 3EEL 53T 7.92079
10 5JBX MLI 8.91089
11 1RJD SAM 15.8416
12 3H0A D30 16.8317
13 1FEC FAD 18.8119
14 3BIY 01K 19.802
15 5G61 FNY 20.7921
16 4QOM PYG 21.7822
Pocket No.: 15; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 26
This union binding pocket(no: 15) in the query (biounit: 3ko0.bio8) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 3H4V NAP None
2 2O07 SPD None
3 2O07 MTA None
4 3BMO NAP 1.9802
5 4CM4 NAP 1.9802
6 4CM8 NAP 1.9802
7 3JQG NAP 1.9802
8 3JQB NAP 1.9802
9 2WD7 NAP 1.9802
10 3JQ7 NAP 1.9802
11 5JDI NAP 1.9802
12 4CLR NAP 1.9802
13 5JCJ NAP 1.9802
14 5K6A NAP 1.9802
15 4CM9 NAP 1.9802
16 4CME NAP 1.9802
17 4CLO NAP 1.9802
18 3JQA NAP 1.9802
19 5JDC NAP 1.9802
20 4CMI NAP 1.9802
21 1Z83 AP5 6.93069
22 4WAS COO 9.90099
23 1MXH NAP 11.8812
24 1MXH DHF 11.8812
25 6BJO DUY 14.8515
26 1DTL BEP 18.8119
Pocket No.: 16; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 14
This union binding pocket(no: 16) in the query (biounit: 3ko0.bio8) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4M4Q 21A None
2 4KM2 ATR None
3 5DHU 5A8 5.94059
4 3KJS DQ1 5.94059
5 5ICE SAH 5.94059
6 5NWI TYR PHE SER SEP ASN 5.94059
7 3I53 SAH 6.93069
8 4E70 N7I 7.92079
9 1Q2C COA 8.91089
10 2AE2 PTO 10.8911
11 2AE2 NAP 10.8911
12 4NB5 2JT 11.8812
13 5BYK A3P 23.7624
14 5BYK OAQ 23.7624
Pocket No.: 17; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 27
This union binding pocket(no: 17) in the query (biounit: 3ko0.bio5) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 1U3R 338 None
2 1YNS HPO None
3 6CB2 OLC None
4 4J24 EST None
5 2C0U FAD NBT 1.9802
6 2YFB SIN 3.9604
7 1SMR PIV HIS PRO PHE HIS LPL TYR TYR SER 4.9505
8 2OO8 RAJ 5.94059
9 3D9F N6C 5.94059
10 2WYA HMG 5.94059
11 4AP9 1PS 6.93069
12 3RJ5 NAD 6.93069
13 3MYU VIB 6.93069
14 2PK3 A2R 7.92079
15 3QDJ ALA ALA GLY ILE GLY ILE LEU THR VAL 7.92079
16 1ZOY UQ1 7.92079
17 2BVN ENX 8.91089
18 2WW4 ADP 9.90099
19 6B3A SAM 11.8812
20 4JRB PGT 14.8515
21 1DIG NAP 16.8317
22 1DIG L37 16.8317
23 2CE7 ADP 16.8317
24 1MV8 NAD 19.802
25 3IB1 IMN 24.7525
26 3LCV SAM 26.7327
27 3EKI TPP 30.6931
Pocket No.: 18; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 6
This union binding pocket(no: 18) in the query (biounit: 3ko0.bio5) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 1EK0 GNP None
2 5WP5 SAH 3.9604
3 4XPL ACO 6.93069
4 4G7A AZM 6.93069
5 2C78 PUL 8.91089
6 1Y8Q ATP 16.8317
Pocket No.: 19; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 17
This union binding pocket(no: 19) in the query (biounit: 3ko0.bio5) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 3TTZ 07N None
2 5DM1 SAH 1.9802
3 5DM1 5D7 1.9802
4 2ADA HPR 3.9604
5 4XYM COA 4.9505
6 3VPD ANP 4.9505
7 3KC1 2T6 5.94059
8 2VYN NAD 5.94059
9 5XLS URA 6.93069
10 2RAB NAD 7.92079
11 2DT5 NAD 7.92079
12 1BZL GCG 8.91089
13 6B5G NAD 13.8614
14 4EMV 0R9 13.8614
15 2B4R NAD 16.8317
16 2B4R AES 16.8317
17 2YNM PMR 30.6931
Pocket No.: 20; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 36
This union binding pocket(no: 20) in the query (biounit: 3ko0.bio5) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5HH0 COA None
2 2FP2 TSA None
3 5U3B 7TD None
4 5CG1 NAD BBN None
5 5HGZ ACO None
6 1QG6 NAD None
7 1QG6 TCL None
8 4PJT 2YQ None
9 4QC6 30N None
10 3G5D 1N1 1.9802
11 1POC GEL 1.9802
12 5LGA 6VH 2.9703
13 3NTD COA 5.94059
14 5DLY 5D7 5.94059
15 3NT6 COA 5.94059
16 2BNE U5P 5.94059
17 4KXL 6C6 6.93069
18 1M13 HYF 6.93069
19 3PVT 3HC 7.92079
20 4M52 M52 8.91089
21 2FZH DH1 8.91089
22 1XCL SAH 8.91089
23 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 10.8911
24 4OGQ 2WD 10.8911
25 3QWB NDP 12.8713
26 1EM6 CP4 13.8614
27 4ZW3 4S9 14.8515
28 3A4X NAG NAG NAG NDG 15.8416
29 1YQZ FAD 16.8317
30 1RDT 570 16.8317
31 5M36 9SZ 18.4211
32 1RM6 FAD 18.8119
33 2YI0 YI0 19.802
34 5AM1 I5T 23.7624
35 2D5Z L35 25.7426
36 3LDW IPE 38.6139
Pocket No.: 21; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 10
This union binding pocket(no: 21) in the query (biounit: 3ko0.bio10) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 5WZU 7W3 None
2 5GUD NDP None
3 5GUD 2IT None
4 1N46 PFA 3.9604
5 4B63 FAD 4.9505
6 4B63 ORN 4.9505
7 4B63 NAP 4.9505
8 3MBG FAD 4.9505
9 3ZUY TCH 5.94059
10 2RHQ GAX 17.8218
Pocket No.: 22; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 17
This union binding pocket(no: 22) in the query (biounit: 3ko0.bio10) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 3K87 FAD None
2 1K0E TRP 1.9802
3 2DM6 IMN 2.9703
4 2C49 ANP 2.9703
5 2JAH NDP 2.9703
6 2JAP NDP 2.9703
7 1MI3 NAD 3.9604
8 5KF9 NAG 3.9604
9 5KF9 COA 3.9604
10 5ESO TDP 4.9505
11 5ESO ISC 4.9505
12 1NVM NAD 4.9505
13 4RI1 ACO 9.90099
14 2YBQ UP2 10.8911
15 1OQC FAD 11.8812
16 3IAE D7K 12.8713
17 6C0B MLI 16.8317
Pocket No.: 23; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 8
This union binding pocket(no: 23) in the query (biounit: 3ko0.bio10) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4WUJ FMN None
2 3VC1 GST 2.9703
3 3WQT ANP 6.93069
4 5KJZ PCG 6.93069
5 5GK9 ACO 11.8812
6 3DAK ANP 16.8317
7 4M5P FMN 17.8218
8 6D5E GNP 19.802
Pocket No.: 24; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 9
This union binding pocket(no: 24) in the query (biounit: 3ko0.bio10) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4URF NAD 2.9703
2 4UHL VFV 4.9505
3 5K6N XYP 6.93069
4 3ZS7 ATP 6.93069
5 4U63 FAD 7.92079
6 3IPQ 965 12
7 5EOU ATP 14.8515
8 2DYS PSC 14.8936
9 2PI8 NAG NAG NAG NAG NAG NAG 24.7525
Pocket No.: 25; Query (leader) PDB : 3KO0; Ligand: TFP; Similar sites found with APoc: 34
This union binding pocket(no: 25) in the query (biounit: 3ko0.bio9) has 9 residues