Receptor
PDB id Resolution Class Description Source Keywords
3IVV 1.25 Å NON-ENZYME: OTHER STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES: S POPMATH-PUCSBC1_PEP1 HOMO SAPIENS PROTEIN BINDING NUCLEUS UBL CONJUGATION PATHWAY LIGASE
Ref.: STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES. MOL.CELL V. 36 39 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ASP GLU VAL THR SER THR THR SER SER SER D:96;
 Valid;
 none;
 Kd = 3.7 uM
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3IVV 1.25 Å NON-ENZYME: OTHER STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES: S POPMATH-PUCSBC1_PEP1 HOMO SAPIENS PROTEIN BINDING NUCLEUS UBL CONJUGATION PATHWAY LIGASE
Ref.: STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES. MOL.CELL V. 36 39 2009
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 6I7A Kd = 55 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
2 6I68 Kd = 13 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
3 3IVV Kd = 3.7 uM ASP GLU VAL THR SER THR THR SER SER SER n/a n/a
4 6I41 Kd = 61 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
5 6I5P Kd = 48 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 6I7A Kd = 55 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
2 6I68 Kd = 13 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
3 3IVV Kd = 3.7 uM ASP GLU VAL THR SER THR THR SER SER SER n/a n/a
4 6I41 Kd = 61 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
5 6I5P Kd = 48 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 6I7A Kd = 55 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
2 6I68 Kd = 13 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
3 3IVV Kd = 3.7 uM ASP GLU VAL THR SER THR THR SER SER SER n/a n/a
4 6I41 Kd = 61 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
5 6I5P Kd = 48 uM LYS ALA ASP THR THR THR PRO THR THR n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ASP GLU VAL THR SER THR THR SER SER SER; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: ASP GLU VAL THR SER THR THR SER SER SER; Similar ligands found: 1
No: Ligand Similarity coefficient
1 ASP GLU VAL THR SER THR THR SER SER SER 1.0000
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3IVV; Ligand: ASP GLU VAL THR SER THR THR SER SER SER; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3ivv.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
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