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Receptor
PDB id Resolution Class Description Source Keywords
3IUY 2.4 Å EC: 3.6.1.- CRYSTAL STRUCTURE OF DDX53 DEAD-BOX DOMAIN HOMO SAPIENS REC-A-LIKE DEAD-BOX STRUCTURAL GENOMICS STRUCTURAL GENOMICONSORTIUM SGC ATP-BINDING HELICASE HYDROLASE NUCLEOTIBINDING NUCLEUS RNA-BINDING
Ref.: COMPARATIVE STRUCTURAL ANALYSIS OF HUMAN DEAD-BOX R HELICASES. PLOS ONE V. 5 12791 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AMP A:160;
B:160;
Valid;
Valid;
none;
none;
submit data
347.221 C10 H14 N5 O7 P c1nc(...
CL A:1;
B:1;
Invalid;
Invalid;
none;
none;
submit data
35.453 Cl [Cl-]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3IUY 2.4 Å EC: 3.6.1.- CRYSTAL STRUCTURE OF DDX53 DEAD-BOX DOMAIN HOMO SAPIENS REC-A-LIKE DEAD-BOX STRUCTURAL GENOMICS STRUCTURAL GENOMICONSORTIUM SGC ATP-BINDING HELICASE HYDROLASE NUCLEOTIBINDING NUCLEUS RNA-BINDING
Ref.: COMPARATIVE STRUCTURAL ANALYSIS OF HUMAN DEAD-BOX R HELICASES. PLOS ONE V. 5 12791 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 28 families.
1 3IUY - AMP C10 H14 N5 O7 P c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 26 families.
1 3IUY - AMP C10 H14 N5 O7 P c1nc(c2c(n....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 24 families.
1 4KBF - AMP C10 H14 N5 O7 P c1nc(c2c(n....
2 5GVR - LMR C4 H6 O5 C([C@@H](C....
3 3B7G - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
4 3MWK - 8OP C10 H14 N5 O8 P c1nc(c2c(n....
5 3NBF - 8OP C10 H14 N5 O8 P c1nc(c2c(n....
6 3DKP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
7 3IUY - AMP C10 H14 N5 O7 P c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AMP; Similar ligands found: 395
No: Ligand ECFP6 Tc MDL keys Tc
1 A 1 1
2 AMP 1 1
3 A2D 0.833333 0.943662
4 ABM 0.833333 0.943662
5 ADP 0.823529 0.971429
6 A12 0.808824 0.931507
7 AP2 0.808824 0.931507
8 BA3 0.808824 0.943662
9 SRA 0.80303 0.944444
10 AP5 0.797101 0.943662
11 B4P 0.797101 0.943662
12 HEJ 0.788732 0.971429
13 ATP 0.788732 0.971429
14 AT4 0.785714 0.931507
15 AN2 0.785714 0.957747
16 5FA 0.777778 0.971429
17 AQP 0.777778 0.971429
18 APC 0.777778 0.931507
19 CA0 0.774648 0.917808
20 M33 0.774648 0.930556
21 AU1 0.774648 0.944444
22 ADX 0.774648 0.848101
23 ACP 0.763889 0.944444
24 50T 0.763889 0.957747
25 25A 0.75641 0.971429
26 AR6 0.753425 0.943662
27 PRX 0.753425 0.917808
28 APR 0.753425 0.943662
29 ACQ 0.746667 0.944444
30 T99 0.746667 0.931507
31 TAT 0.746667 0.931507
32 SAP 0.743243 0.918919
33 AD9 0.743243 0.944444
34 AGS 0.743243 0.918919
35 RBY 0.743243 0.905405
36 ADV 0.743243 0.905405
37 ANP 0.723684 0.944444
38 ADP PO3 0.72 0.942857
39 6YZ 0.717949 0.944444
40 5AL 0.714286 0.930556
41 SON 0.712329 0.931507
42 LMS 0.710145 0.825
43 RAB 0.709677 0.842857
44 XYA 0.709677 0.842857
45 ADN 0.709677 0.842857
46 ATF 0.705128 0.931507
47 GAP 0.701299 0.891892
48 A22 0.7 0.957747
49 SRP 0.696203 0.905405
50 7D5 0.691176 0.902778
51 A3P 0.684932 0.971014
52 A2P 0.684932 0.956522
53 ADP ALF 0.683544 0.868421
54 ALF ADP 0.683544 0.868421
55 ADQ 0.682927 0.917808
56 MAP 0.679012 0.918919
57 ADP VO4 0.675 0.930556
58 VO4 ADP 0.675 0.930556
59 OOB 0.670732 0.930556
60 9ZA 0.670732 0.906667
61 8QN 0.670732 0.930556
62 5SV 0.670732 0.87013
63 9ZD 0.670732 0.906667
64 PTJ 0.670588 0.894737
65 AOC 0.666667 0.84507
66 PAJ 0.662651 0.858974
67 4AD 0.662651 0.893333
68 A3R 0.662651 0.881579
69 A1R 0.662651 0.881579
70 AMO 0.662651 0.905405
71 5N5 0.661538 0.816901
72 DAL AMP 0.658537 0.90411
73 IMO 0.657534 0.928571
74 AHX 0.654762 0.87013
75 00A 0.654762 0.881579
76 DLL 0.654762 0.930556
77 5AS 0.653333 0.776471
78 A4D 0.651515 0.816901
79 5CD 0.651515 0.828571
80 9X8 0.647059 0.893333
81 OAD 0.647059 0.917808
82 3UK 0.647059 0.917808
83 ADP BMA 0.647059 0.891892
84 25L 0.643678 0.957747
85 PR8 0.639535 0.848101
86 WAQ 0.639535 0.881579
87 LAD 0.639535 0.858974
88 B5V 0.639535 0.905405
89 DTA 0.637681 0.808219
90 V3L 0.6375 0.971429
91 3DH 0.633803 0.794521
92 BIS 0.632184 0.906667
93 ME8 0.632184 0.8375
94 3OD 0.632184 0.917808
95 FYA 0.632184 0.930556
96 NB8 0.632184 0.87013
97 1ZZ 0.632184 0.8375
98 TXA 0.632184 0.905405
99 MTA 0.628571 0.794521
100 3AM 0.625 0.956522
101 EP4 0.623188 0.773333
102 A A 0.62069 0.971429
103 9SN 0.617977 0.87013
104 M2T 0.614286 0.753247
105 JB6 0.613636 0.881579
106 YAP 0.611111 0.893333
107 B5Y 0.611111 0.893333
108 FA5 0.611111 0.905405
109 B5M 0.611111 0.893333
110 MYR AMP 0.606742 0.814815
111 G5A 0.604938 0.776471
112 XAH 0.604396 0.8375
113 4UV 0.597826 0.893333
114 71V 0.597403 0.906667
115 ATP A A A 0.593407 0.929577
116 PAP 0.592593 0.957143
117 G3A 0.591398 0.894737
118 2AM 0.589041 0.942857
119 5X8 0.5875 0.783784
120 6RE 0.586667 0.779221
121 6C6 0.585366 0.905405
122 AFH 0.585106 0.858974
123 4UU 0.585106 0.893333
124 G5P 0.585106 0.894737
125 GA7 0.585106 0.905405
126 7D3 0.584416 0.878378
127 A5A 0.583333 0.804878
128 TSB 0.581395 0.795181
129 AMP DBH 0.580645 0.891892
130 TYR AMP 0.580645 0.868421
131 2A5 0.580247 0.891892
132 DQV 0.578947 0.930556
133 DSH 0.578947 0.74359
134 GTA 0.578947 0.860759
135 TAD 0.578947 0.858974
136 6IA 0.578313 0.858974
137 SSA 0.576471 0.776471
138 AMZ 0.575342 0.888889
139 C2R 0.575342 0.876712
140 PGS 0.575 0.857143
141 7D4 0.575 0.878378
142 ZAS 0.573333 0.786667
143 ATR 0.573171 0.942857
144 LAQ 0.572917 0.8375
145 AAM 0.571429 1
146 J7C 0.571429 0.789474
147 A3N 0.571429 0.783784
148 PPS 0.571429 0.848101
149 AIR 0.571429 0.927536
150 52H 0.569767 0.776471
151 54H 0.569767 0.785714
152 VMS 0.569767 0.785714
153 AR6 AR6 0.568421 0.916667
154 ARG AMP 0.568421 0.82716
155 7MD 0.568421 0.8375
156 YLP 0.56701 0.817073
157 48N 0.56701 0.87013
158 OVE 0.565789 0.90411
159 UPA 0.565657 0.881579
160 2SA 0.564706 0.905405
161 S4M 0.564103 0.682353
162 5CA 0.563218 0.776471
163 53H 0.563218 0.776471
164 8X1 0.563218 0.75
165 UP5 0.561224 0.893333
166 NAI 0.561224 0.881579
167 6V0 0.561224 0.87013
168 NAX 0.561224 0.848101
169 4UW 0.561224 0.858974
170 DND 0.561224 0.905405
171 TXD 0.561224 0.881579
172 NXX 0.561224 0.905405
173 NIA 0.56 0.820513
174 D5M 0.558442 0.902778
175 DA 0.558442 0.902778
176 MAO 0.556962 0.777778
177 AHZ 0.556701 0.814815
178 OMR 0.555556 0.82716
179 ITT 0.555556 0.915493
180 TYM 0.555556 0.905405
181 TXE 0.555556 0.881579
182 5AD 0.552239 0.768116
183 A2R 0.551724 0.957747
184 LPA AMP 0.55102 0.814815
185 DSZ 0.550562 0.776471
186 NSS 0.550562 0.776471
187 LSS 0.550562 0.758621
188 AP0 0.55 0.87013
189 YLC 0.55 0.8375
190 4TC 0.55 0.87013
191 YLB 0.55 0.817073
192 P5A 0.549451 0.741573
193 139 0.54902 0.848101
194 A4P 0.544554 0.819277
195 NVA LMS 0.544444 0.75
196 GJV 0.544304 0.769231
197 7D7 0.544118 0.763889
198 9K8 0.543478 0.711111
199 A7D 0.54321 0.797297
200 AF3 ADP 3PG 0.54 0.835443
201 6K6 0.539326 0.957143
202 IOT 0.539216 0.829268
203 A3G 0.538462 0.797297
204 LEU LMS 0.538462 0.75
205 A5D 0.535714 0.808219
206 7MC 0.534653 0.817073
207 T5A 0.533981 0.817073
208 ADJ 0.533981 0.82716
209 YLA 0.533981 0.817073
210 GSU 0.532609 0.776471
211 KAA 0.532609 0.75
212 7RA 0.531646 0.985507
213 SFG 0.53012 0.77027
214 SAH 0.529412 0.763158
215 HFD 0.529412 0.918919
216 AYB 0.528846 0.807229
217 CNA 0.528846 0.905405
218 N6P 0.527473 0.942029
219 8BR 0.525 0.931507
220 F2R 0.52381 0.839506
221 80F 0.523364 0.817073
222 Y3J 0.521127 0.746479
223 YSA 0.520833 0.776471
224 7RP 0.518987 0.955882
225 BTX 0.518868 0.839506
226 NAD 0.518868 0.930556
227 COD 0.518868 0.788235
228 G A A A 0.518868 0.87013
229 MHZ 0.518072 0.714286
230 SA8 0.517647 0.725
231 6AD 0.517241 0.883117
232 DZD 0.514019 0.858974
233 BT5 0.514019 0.829268
234 RMB 0.5125 0.898551
235 SAI 0.511628 0.753247
236 AV2 0.511364 0.890411
237 8PZ 0.510417 0.776471
238 A3D 0.509259 0.917808
239 A3S 0.506024 0.808219
240 3AT 0.505747 0.943662
241 SAM 0.505747 0.707317
242 SMM 0.505618 0.702381
243 NA7 0.505376 0.931507
244 4TA 0.504673 0.804878
245 AMP NAD 0.504673 0.90411
246 EEM 0.5 0.707317
247 G 0.5 0.905405
248 NEC 0.5 0.743243
249 5GP 0.5 0.905405
250 AAT 0.5 0.725
251 YLY 0.495495 0.807229
252 M24 0.495495 0.848101
253 7C5 0.494949 0.815789
254 DAT 0.494118 0.878378
255 A3T 0.494118 0.819444
256 P2P 0.493827 0.928571
257 FAI 0.493827 0.888889
258 1RB 0.493671 0.911765
259 NAE 0.491071 0.893333
260 U A 0.490909 0.906667
261 NAJ PZO 0.490909 0.846154
262 A G 0.490741 0.881579
263 TM1 0.489583 0.771084
264 A A A 0.489362 0.90411
265 A6D 0.489362 0.740741
266 PO4 PO4 A A A A PO4 0.489362 0.901408
267 S7M 0.488889 0.707317
268 DTP 0.488636 0.878378
269 RBZ 0.4875 0.873239
270 101 0.4875 0.902778
271 EAD 0.486957 0.848101
272 NAQ 0.486726 0.87013
273 U A G G 0.486239 0.881579
274 4YB 0.485149 0.758621
275 NDE 0.483051 0.931507
276 ZID 0.482456 0.917808
277 N0B 0.482456 0.817073
278 WSA 0.480769 0.785714
279 RGT 0.479592 0.931507
280 ARU 0.478723 0.835443
281 GGZ 0.478261 0.8
282 JLN 0.47561 0.863014
283 ANZ 0.475248 0.820513
284 QQY 0.475 0.837838
285 ACK 0.475 0.885714
286 NAJ PYZ 0.473684 0.804878
287 S8M 0.473118 0.779221
288 GEK 0.473118 0.734177
289 AVV 0.473118 0.87013
290 3AD 0.472973 0.828571
291 A U 0.471698 0.868421
292 P1H 0.470588 0.82716
293 0UM 0.468085 0.716049
294 RVP 0.467532 0.847222
295 649 0.466667 0.741573
296 Z5A 0.465517 0.776471
297 PMO 0.464286 0.873239
298 SXZ 0.463918 0.707317
299 62X 0.463158 0.682353
300 QQX 0.4625 0.826667
301 8Q2 0.462264 0.75
302 2VA 0.45977 0.797297
303 IMP 0.458824 0.90411
304 K15 0.458333 0.698795
305 CC5 0.458333 0.84058
306 AS 0.457831 0.855263
307 DDS 0.455556 0.851351
308 V1N 0.455446 0.943662
309 NJP 0.454545 0.918919
310 7DD 0.453488 0.957143
311 93A 0.453488 0.804878
312 G7M 0.453488 0.87013
313 3L1 0.453333 0.77027
314 3D1 0.453333 0.77027
315 EO7 0.452381 0.785714
316 NDC 0.45082 0.87013
317 FB0 0.45082 0.781609
318 0WD 0.45045 0.894737
319 NVA 2AD 0.449438 0.75641
320 26A 0.447368 0.76
321 2FA 0.447368 0.810811
322 2BA 0.447059 0.914286
323 CMP 0.447059 0.927536
324 D3Y 0.446809 0.786667
325 KB1 0.444444 0.716049
326 APU 0.444444 0.893333
327 VRT 0.444444 0.766234
328 SO8 0.444444 0.786667
329 FDA 0.443548 0.809524
330 PUA 0.443478 0.858974
331 ODP 0.441441 0.883117
332 6FA 0.44 0.817073
333 103 0.439024 0.861111
334 RP1 0.439024 0.864865
335 SP1 0.439024 0.864865
336 3NZ 0.438776 0.779221
337 A C A C 0.438596 0.846154
338 7DT 0.438202 0.957143
339 NDP 0.436364 0.894737
340 NPW 0.436364 0.860759
341 MTP 0.434211 0.727273
342 FAS 0.433071 0.82716
343 SFD 0.433071 0.712766
344 FAD 0.433071 0.82716
345 IRN 0.432432 0.867647
346 ZZB 0.432432 0.792683
347 TXP 0.432432 0.894737
348 NZQ 0.432432 0.883117
349 62F 0.430769 0.8375
350 FNK 0.430769 0.781609
351 128 0.429907 0.752941
352 1DA 0.428571 0.842857
353 6MD 0.428571 0.805556
354 PAX 0.428571 0.82716
355 SLU 0.426087 0.767442
356 XNP 0.424779 0.848101
357 12D 0.424528 0.761905
358 5F1 0.423077 0.72973
359 ETB 0.422414 0.809524
360 DCA 0.422414 0.8
361 F0P 0.422018 0.725
362 WMP 0.421053 0.864865
363 GUO 0.421053 0.864865
364 FAY 0.416667 0.8375
365 38Y 0.415929 0.804878
366 5J9 0.415842 0.728395
367 COA 0.415254 0.8
368 0T1 0.415254 0.8
369 KH3 0.415094 0.690476
370 U A C C 0.413793 0.857143
371 N01 0.413793 0.90411
372 FMP 0.413793 0.871429
373 RFL 0.413534 0.797619
374 NMN AMP PO4 0.412281 0.868421
375 GP2 0.408602 0.858974
376 GDP 0.408602 0.893333
377 NAP 0.408333 0.944444
378 NOC 0.407895 0.760563
379 2ER 0.405941 0.831169
380 1PR 0.405941 0.820513
381 P5F 0.405797 0.8
382 CAO 0.404959 0.772727
383 TAP 0.404959 0.906667
384 30N 0.404959 0.731183
385 COS 0.404959 0.781609
386 AMX 0.404959 0.809524
387 XMP 0.402299 0.891892
388 G2P 0.402062 0.858974
389 APC G U 0.401709 0.833333
390 U A A U 0.401639 0.906667
391 CMX 0.401639 0.8
392 NA0 0.401639 0.931507
393 SCO 0.401639 0.8
394 9JJ 0.40146 0.8375
395 F2N 0.4 0.790698
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3IUY; Ligand: AMP; Similar sites found with APoc: 648
This union binding pocket(no: 1) in the query (biounit: 3iuy.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 2KIN ADP None
2 2GCN GDP None
3 1G3Q ADP None
4 1KY3 GDP None
5 4BQS K2Q None
6 4BQS ADP None
7 3R96 ACO None
8 3R96 AMP None
9 1DCP HBI None
10 2GCO GNP None
11 3B5J 12D None
12 1KMQ GNP None
13 1CXZ GSP None
14 1VG8 GNP 1.44928
15 3W5J GDP 1.47059
16 1VG1 GDP 1.62162
17 3E5H GNP 1.68539
18 2OZE AGS 1.75439
19 5HCN GCP 1.75439
20 1JI0 ATP 1.75439
21 4M0R 644 1.75439
22 5G3Y ADP 1.76991
23 3RAB GNP 1.77515
24 3GJ8 GDP 1.80995
25 3GJ0 GDP 1.80995
26 3GJ4 GDP 1.80995
27 4NU0 AP5 1.84332
28 1XX6 ADP 2.09424
29 4U00 ADP 2.19298
30 2OBM ADP 2.19298
31 4IDN GNP 2.19298
32 5WC2 ADP 2.19298
33 2R42 FPS 2.19298
34 5TIV A3P 2.19298
35 1R6B ADP 2.19298
36 2V2V V12 2.19298
37 5YT0 GDP 2.19298
38 2GKS ADP 2.19298
39 1DAK ADP 2.23214
40 1DAK DPU 2.23214
41 6BSX GDP 2.24719
42 6BSX E7S 2.24719
43 1G16 GDP 2.35294
44 5BXQ GDP 2.3622
45 4BAS GNP 2.51256
46 1Q20 A3P 2.63158
47 1Q20 PLO 2.63158
48 1ION ADP 2.63158
49 1P72 ADP 2.63158
50 5MEX PAP 2.63158
51 5MEX SZZ 2.63158
52 4NON GDP 2.63158
53 1QF5 GDP 2.63158
54 1QF5 RPL 2.63158
55 1YRB GDP 2.63158
56 6BA2 7KM 2.63158
57 3B9Q MLI 2.63158
58 4D0N GDP 2.63158
59 2OG2 MLI 2.63158
60 4B47 GDP 2.63158
61 4B5W PYR 2.63158
62 1VKJ A3P 2.63158
63 5G41 AP5 2.69058
64 3AQ4 GDP 2.71739
65 3TMK T5A 2.77778
66 1Z0F GDP 2.7933
67 1CS4 GSP 2.83019
68 3LN9 FLC 2.8777
69 2OFW ADX 2.88462
70 2QG6 NMN 3.01508
71 1S9D GDP 3.04878
72 4WOP CTP 3.07018
73 5WRJ A3P 3.07018
74 4GOX A3P 3.07018
75 1E2K TMC 3.07018
76 5EXT ADP 3.07018
77 2X7I CIT 3.07018
78 4ITM ATP 3.07018
79 3NHB ADP 3.07018
80 1L2T ATP 3.07018
81 2BIF ANP 3.07018
82 2BIF SIN 3.07018
83 6B8B ADP 3.07018
84 4PFO ADP 3.07018
85 3FKQ ATP 3.07018
86 1BG2 ADP 3.07018
87 5M04 GDP 3.07018
88 4R43 GDP 3.07018
89 5OJI ISN 3.07018
90 1UJ2 ADP 3.07018
91 5OJI NAP 3.07018
92 1SVI GDP 3.07692
93 1RE0 GDP 3.16742
94 1GXU 2HP 3.2967
95 2YOH WMJ 3.33333
96 4R57 ACO 3.40909
97 1KO8 6PG 3.42857
98 2GJ8 ALF GDP 3.48837
99 3A1S GDP 3.48837
100 3UIE ANP 3.5
101 4ZNL BEF ADP 3.50877
102 2O0J ADP 3.50877
103 4PJ3 ANP 3.50877
104 4JLV ADP 3.50877
105 1J99 AND 3.50877
106 2DPY ADP 3.50877
107 2WOJ ADP ALF 3.50877
108 4UTG ANP 3.50877
109 4V03 ADP 3.50877
110 2Z5F A3P 3.50877
111 2ZPT A3P 3.50877
112 4OHY ANP 3.50877
113 4R98 GNH 3.50877
114 3THR C2F 3.50877
115 1SVM ATP 3.50877
116 1H74 ADP 3.50877
117 3HU3 AGS 3.50877
118 3EZ2 ADP 3.50877
119 2WIC GNP 3.50877
120 4LPS GDP 3.50877
121 5HPY GDP 3.50877
122 1TAD ALF 3.50877
123 1TAD GDP 3.50877
124 4AUT FAD 3.50877
125 1PUJ GNP 3.50877
126 1RRC ADP 3.50877
127 1PR9 NAP 3.50877
128 5W75 GDP 3.50877
129 1Z08 GNP 3.52941
130 1ZUI SKM 3.57143
131 2WJH FLC 3.61446
132 2WJH GDP 3.61446
133 5Z2M GTP 3.62319
134 4MKF AP5 3.68664
135 4DKX GDP 3.7037
136 2WJG GDP 3.7234
137 2PEZ DAT 3.91061
138 2PEZ GGZ 3.91061
139 5SZH GNP 3.94089
140 1F5N GNP 3.94737
141 3IO3 ADP 3.94737
142 4PPF FLC 3.94737
143 5MZN ADP 3.94737
144 4XVU ATP 3.94737
145 4XTR ATP 3.94737
146 5L3R GCP 3.94737
147 4XTR ADP 3.94737
148 3Q9L ATP 3.94737
149 2B8W ALF 5GP 3.94737
150 5K5Z ANP 3.94737
151 3H4S ADP 3.94737
152 5BYK OAQ 3.94737
153 5BYK A3P 3.94737
154 1XKV ATP 3.94737
155 5CK5 GDP 3.94737
156 1NJF ADP 3.94737
157 4HI0 GDP 3.94737
158 4FRZ ADP 3.94737
159 3T34 GDP 3.94737
160 5I34 GDP 3.94737
161 5ZXD ATP 3.94737
162 5EP2 AZU 3.94737
163 1NJF AGS 3.94737
164 2ZR9 DTP 3.94737
165 1SKQ GDP 3.94737
166 2R3A SAM 3.94737
167 4J0Q GDP 3.94737
168 2QZ4 ADP 3.94737
169 2ORV 4TA 3.94737
170 6BCA GSP 3.97351
171 2EW1 GNP 3.9801
172 6BC0 GSP 4
173 1YAG ATP 4
174 4LHW GNP 4.02299
175 3QBT GNP 4.02299
176 1TX4 ALF GDP 4.0404
177 5JCP GDP ALF 4.05728
178 6BYF CIT 4.11765
179 1OW3 GDP 4.13223
180 4V0K GDP 4.14201
181 1ZIN AP5 4.14747
182 5OCG GNP 4.2328
183 1YZN GNP 4.32432
184 2QQ0 ADP 4.34783
185 2QQ0 TMP 4.34783
186 2QQ0 ANP 4.34783
187 4E03 ADP 4.36893
188 2RGX AP5 4.36893
189 3BFV ADP 4.38596
190 4H1V GNP 4.38596
191 4LC1 GDP 4.38596
192 3MGB PAP 4.38596
193 3NOJ PYR 4.38596
194 5UQW GDP 4.38596
195 3GJX GTP 4.38596
196 3MD0 GDP 4.38596
197 2WKQ GTP 4.38596
198 5BN3 ADP 4.38596
199 2VWT PYR 4.38596
200 1YTM ATP 4.38596
201 1S7N COA 4.3956
202 2HF9 GSP 4.42478
203 2Y8E GNP 4.46927
204 1DAR GDP 4.48625
205 1X1R GDP 4.49438
206 2F9L GDP 4.52261
207 1LVG ADP 4.54545
208 1F6B GDP 4.54545
209 3NKV GNP 4.57143
210 1ZC3 GNP 4.57143
211 1UAD GNP 4.57143
212 1W4R TTP 4.61538
213 3BC1 GNP 4.61538
214 4YLG GDP 4.62428
215 6FA4 GNP 4.62428
216 3REF GDP 4.63918
217 6EDV COA 4.63918
218 3LXR GDP 4.6875
219 4TMK T5A 4.69484
220 1YZQ GNP 4.70588
221 4KFU ACP 4.71698
222 3Q85 GNP 4.73373
223 1U8Z GDP 4.7619
224 4KVG GTP 4.7619
225 1LFD GNP 4.79042
226 1CLU DBG 4.81928
227 3DDC GNP 4.81928
228 2UZI GTP 4.81928
229 3E70 GDP 4.82456
230 4AG5 ADP 4.82456
231 6CS8 F9Y 4.82456
232 4GBM A3P 4.82456
233 1WDT GTP 4.82456
234 2CBZ ATP 4.82456
235 4LYA ATP 4.82456
236 4K81 GTP 4.82456
237 6A20 ADP 4.82456
238 5WDR GNP 4.82456
239 1K6M AGS 4.82456
240 4BFW ZVW 4.82456
241 2CE7 ADP 4.82456
242 2D2F ADP 4.82456
243 3W8X FTK 4.82456
244 3W8X FAD 4.82456
245 1IID NHM 4.82456
246 6G14 G4P 4.82456
247 5ZBR ANP 4.82456
248 3RWO GDP 4.86486
249 2ZEJ GDP 4.8913
250 2A9K GDP 4.93274
251 2CDN ADP 4.97512
252 5JCZ GDP 5.02793
253 1VHT BA3 5.04587
254 1HTW ADP 5.06329
255 4LX0 BEF GDP 5.08475
256 3H86 AP5 5.20833
257 2CJW GDP 5.20833
258 2HV8 GTP 5.23256
259 2XT3 ADP 5.26316
260 3FWY ADP 5.26316
261 3ZS9 ADP ALF 5.26316
262 1FNN ADP 5.26316
263 2XTN GTP 5.26316
264 3CPJ GDP 5.26316
265 3A4M ADP 5.26316
266 2BCG GDP 5.26316
267 1D2N ANP 5.26316
268 1WA5 GTP 5.26316
269 5IRN ADP 5.26316
270 5M7P ADP 5.26316
271 2FNA ADP 5.26316
272 2ZW5 COA 5.26316
273 3CNL GNP 5.26316
274 2HIM ASP 5.26316
275 1WQ1 GDP 5.26316
276 4ZDJ UTP 5.26316
277 2D7C GTP 5.38922
278 1FQK GDP 5.44218
279 3KTA AP5 5.49451
280 1XEX ATP 5.49451
281 5N69 ADP 5.52764
282 2G77 GDP 5.55556
283 4C4P GNP 5.60748
284 4X8O AP5 5.60748
285 5L3V GDP 5.70175
286 1IHU AF3 5.70175
287 1IHU ADP 5.70175
288 1VG9 GDP 5.70175
289 1VG0 GDP 5.70175
290 2WHX ADP 5.70175
291 1NVV GNP 5.70175
292 4KVA GTP 5.70175
293 6D5G GNP 5.70175
294 6D5V GNP 5.70175
295 6D56 GNP 5.70175
296 6D55 GNP 5.70175
297 6D5L GNP 5.70175
298 6D59 GNP 5.70175
299 6D5M GNP 5.70175
300 6D5E GNP 5.70175
301 6D5J GNP 5.70175
302 6BVJ GNP 5.70175
303 6BVL GNP 5.70175
304 6BVM GNP 5.70175
305 6BVK GNP 5.70175
306 6D5H GNP 5.70175
307 6BVI GNP 5.70175
308 1OXV ANP 5.70175
309 2VVG ADP 5.70175
310 3QKT ANP 5.70175
311 1T8U UAP SGN IDS SGN 5.70175
312 1T8U A3P 5.70175
313 5ERG SAM 5.70175
314 2HT6 GDP 5.74713
315 1B7T ADP 5.76923
316 1Z06 GNP 5.82011
317 2X77 GDP 5.82011
318 3GJ5 GDP 5.88235
319 2J9C ATP 5.88235
320 2IYL GDP 5.98592
321 3Q72 GNP 6.0241
322 2VB6 ADP BEF 6.04027
323 3GJ3 GDP 6.06061
324 1MR3 G3D 6.07735
325 3VX3 ADP 6.14035
326 2FSH ANP 6.14035
327 1IWE IMP 6.14035
328 3KJI ADP 6.14035
329 1IBR GNP 6.14035
330 4ZG4 VO4 ADP 6.14035
331 2A2C NG1 6.14035
332 2A2C ADP 6.14035
333 4ZKD GDP 6.14035
334 1W7J ADP BEF 6.14035
335 1YQT ADP 6.14035
336 3U6B GDP 6.14035
337 4PC3 GDP 6.14035
338 1M5B BN1 6.14035
339 2Q2Y MKR 6.14035
340 5I0H ADP BEF 6.14035
341 2Q2Y ADP 6.14035
342 4KQW NAP 6.14035
343 3WXM GTP 6.14035
344 5HR5 ADP 6.14035
345 1U0J ADP 6.14035
346 1R0X ATP 6.14035
347 4L80 OXL 6.14035
348 1D8T GDP 6.14035
349 4M9Q GNP 6.1674
350 1ZD9 GDP 6.38298
351 2ODE ALF GDP 6.38298
352 1RYH GNP 6.40394
353 5O2T GSP 6.41711
354 4QM7 GTP 6.43275
355 2BME GNP 6.45161
356 3WR7 COA 6.47059
357 1KK8 BEF ADP 6.47482
358 2W2X GSP 6.48649
359 1YVD GNP 6.50888
360 4UXH T5A 6.52174
361 4RZ3 ADP 6.57895
362 6DEF GCP 6.57895
363 4P4T GDP 6.57895
364 2PZE ATP 6.57895
365 4R2I ANP 6.57895
366 4TL6 ANP 6.57895
367 1GP2 GDP 6.57895
368 6CRK GDP 6.57895
369 1V8K ANP 6.57895
370 3QF7 ANP 6.57895
371 4XOI GTP 6.57895
372 3BFX A3P 6.57895
373 4O0L NDP 6.57895
374 5YV5 ADP 6.57895
375 1GOJ ADP 6.57895
376 3PQC GDP 6.66667
377 4DID GDP 6.73575
378 4U5X GNP 6.74157
379 1DS6 GDP 6.77083
380 1I4D GDP 6.77083
381 1A4R GNH 6.80628
382 4ITR GDP 6.80628
383 1GRN GDP 6.80628
384 2NGR GDP 6.80628
385 1A4R GDP 6.80628
386 2WMO GTP 6.84211
387 1B0U ATP 6.87023
388 5YGE ACO 6.89655
389 4XGU ADP 7.01754
390 1TU3 GNP 7.01754
391 1H65 GDP 7.01754
392 1G6O ADP 7.01754
393 4WZ6 ATP 7.01754
394 1AQU A3P 7.01754
395 3BOS CDP 7.01754
396 5DI3 GNP 7.02703
397 5UPK GNP 7.02703
398 5UIV ADP 7.04846
399 4KVX ACO 7.05128
400 1R2Q GNP 7.05882
401 1G4U GDP 7.06522
402 5O74 GDP 7.1066
403 5OEC GDP 7.1066
404 3MJH GTP 7.14286
405 1Z2A GDP 7.14286
406 4YC7 GNP 7.18232
407 1KAO GDP 7.18563
408 3T5G GDP 7.23684
409 1JJV ATP 7.28155
410 1E96 GTP 7.29167
411 4CVN ADP 7.32984
412 2A5J GDP 7.32984
413 5TB5 GDP 7.33333
414 1S3G AP5 7.37327
415 5BQ5 ADP BEF 7.40741
416 2A5F GTP 7.42857
417 5TAR GDP 7.43243
418 1QHH ATP 7.45614
419 1F9V ADP 7.45614
420 3TK1 GDP 7.45614
421 4HSE ADP 7.45614
422 3ZFD ANP 7.45614
423 5YVT NAI 7.45614
424 2GWH A3P 7.45614
425 3CV2 OXL 7.45614
426 3CX8 GSP 7.45614
427 1QHG ATP 7.45614
428 3AB3 GDP 7.45614
429 2ZPA ADP 7.45614
430 1ZCB GDP 7.45614
431 3SBD GNP 7.48663
432 1MH1 GNP 7.52688
433 6BCB GSP 7.53425
434 1EK0 GNP 7.64706
435 4L9Z OXL 7.66962
436 4KAX GTP 7.69231
437 1QF9 ADP 7.73196
438 1QF9 C5P 7.73196
439 1QF9 ALF 7.73196
440 4HDO GNP 7.78443
441 3X1Z GNP 7.78443
442 4HDQ GNP 7.78443
443 2W83 GTP 7.87879
444 5VGR GDP 7.89474
445 1D8C GLV 7.89474
446 1Q19 SSC 7.89474
447 1P7T PYR 7.89474
448 1SVK ALF GDP 7.89474
449 5IFS ADP 7.89474
450 2ZFI ADP 7.89474
451 1Y3A GDP 7.89474
452 3DC4 ADP 7.89474
453 4YMU ATP 7.89474
454 1W0J ADP BEF 7.89474
455 1BH2 GSP 7.89474
456 1W0J ADP 7.89474
457 3N5C GDP 8.02469
458 1Z0A GDP 8.04598
459 2CK3 ANP 8.21918
460 2CK3 ADP 8.21918
461 2V7Q ATP 8.21918
462 2V7Q ADP 8.21918
463 5TSH ADP 8.33333
464 1RJ9 GCP 8.33333
465 5TSH ANP 8.33333
466 5GOE GDP 8.33333
467 4NE2 ADP 8.33333
468 4NE2 SH2 8.33333
469 1G6H ADP 8.33333
470 1SQ5 ADP 8.33333
471 1T5C ADP 8.33333
472 1S8F GDP 8.47458
473 2F3R G5P 8.69565
474 1F2U ATP 8.72483
475 2IL4 COA 8.73786
476 1G3M A3P 8.77193
477 1G3M PCQ 8.77193
478 3EC1 GDP 8.77193
479 2D7D ADP 8.77193
480 1LVK MNT BEF 8.77193
481 4IOK ADP 8.77193
482 4IOK XPO 8.77193
483 4IEE AGS 8.77193
484 1WF3 GNP 8.77193
485 1MKY GDP 8.77193
486 4XSH GSP 9.13242
487 2FH5 GTP 9.18919
488 3COB ADP 9.21053
489 1NST A3P 9.21053
490 2GMV UN8 9.21053
491 2GMV PEP 9.21053
492 1NHX FTB 9.21053
493 1NHX PEP 9.21053
494 2FJU GSP 9.21053
495 4D81 ADP 9.21053
496 4B1W ATP 9.21053
497 2FXU ATP 9.21053
498 1D2E GDP 9.21053
499 1GWN GTP 9.26829
500 1I1D 16G 9.31677
501 1Z0J GTP 9.41177
502 3CH5 GDP 9.61539
503 5LB3 ADP 9.64912
504 3DEF GDP 9.64912
505 3ZIA ADP 9.83607
506 3ZIA ATP 9.83607
507 2J0V GDP 9.90566
508 1M7G AV2 9.95261
509 1M7G ADP 9.95261
510 1M7G ADX 9.95261
511 5KUT GDP 10.0529
512 1X8J A3P 10.0877
513 2NCD ADP 10.0877
514 1Z6T ADP 10.0877
515 4DCT GDP 10.0877
516 1NRJ GTP 10.0917
517 3GJ7 GDP 10.2041
518 2C5L GTP 10.2564
519 1M7B GTP 10.3261
520 3PCR GTP 10.4938
521 5WRI A3P 10.5263
522 5FHD ADP ALF 10.5263
523 5FTB ANP 10.5263
524 1X6V ADP 10.5263
525 1M2O GNP 10.5263
526 3IIJ ADP 10.5556
527 2CHG ANP 10.6195
528 3DOE GTP 10.9375
529 3P4X ADP 10.9649
530 1G7C 5GP 10.9649
531 5U32 GDP 10.9649
532 1NY5 ADP 10.9649
533 2KCE D16 10.9649
534 2XTZ GSP 10.9649
535 3T1O GDP 11.1111
536 2OM2 GDP 11.1111
537 3T12 GDP ALF 11.1111
538 3FB4 AP5 11.1111
539 2ZFZ ARG 11.3924
540 5AK0 8V1 11.4035
541 1Z0K GTP 11.5942
542 5WLB GNP 11.7647
543 4IHQ ADP 11.8421
544 3LRE ADP 11.8421
545 2O66 FLC 11.8519
546 2QTV GNP 11.976
547 5LEF GTP 12.1212
548 2EFE GNH 12.1547
549 2JAQ DCP 12.1951
550 3ZQ6 ADP ALF 12.2807
551 2AWN ADP 12.2807
552 5UWH GNP 12.2807
553 5UWO GNP 12.2807
554 5DHF GNP 12.2807
555 5UWP GNP 12.2807
556 5UWW GNP 12.2807
557 4HAT GNP 12.2807
558 6CIT GNP 12.2807
559 5DIF GNP 12.2807
560 5UWS GNP 12.2807
561 5UWI GNP 12.2807
562 5UWT GNP 12.2807
563 5DI9 GNP 12.2807
564 3WYF GTP 12.2807
565 5UWJ GNP 12.2807
566 2G86 UMP 12.2807
567 3M1I GTP 12.2807
568 3RLF ANP 12.2807
569 5UWU GNP 12.2807
570 1GUA GNP 12.3457
571 3KUD GDP 12.3457
572 2W58 ADP 12.3762
573 1Y63 ADP 12.5
574 3WYG GTP 12.6374
575 1J2J GTP 12.6506
576 2J59 GTP 12.6506
577 1O3Y GTP 12.6506
578 5L3S GNP 12.7193
579 1TQ4 GDP 12.7193
580 3V2U ATP 12.7193
581 3QVV A3P 12.7193
582 3QVV 3QV 12.7193
583 1OS1 ATP 12.7193
584 1OS1 PYR 12.7193
585 3WYA GDP 12.7193
586 1ZJ6 G3D 12.8342
587 2QN6 GDP 12.9032
588 4OI4 ATP 13.1579
589 1YZG GDP 13.4078
590 1JJ7 ADP 13.5965
591 4YDS ATP 14.0351
592 1OIV GDP 14.1361
593 1OIX GDP 14.1361
594 5H68 AGS 14.4737
595 5ZB0 ADP 14.6465
596 5ZB0 TYD 14.6465
597 5KDO GDP 14.8649
598 4NCN GTP 14.9123
599 1KSH GDP 15.0538
600 1GOT GDP 15.0685
601 4ZI2 GNP 15.2632
602 4GOJ GNP 15.3439
603 4TTQ ATP 15.3488
604 4YS0 ADP 15.3509
605 3DZD ADP 15.3509
606 6C90 ADP 15.3846
607 1D5C GDP 15.4321
608 4P3Y GDP 15.9341
609 1FZQ GDP 16.0221
610 3TNF GNP 16.2281
611 3TKL GTP 16.2281
612 3SFV GDP 16.2281
613 3B8I OXL 16.2281
614 5XKT GNP 16.5
615 5L3W GDP 16.6667
616 2BEK ATP 16.6667
617 1P9B GDP 17.5439
618 5J1J ANP 17.5439
619 1Z83 AP5 17.8571
620 6F5Z SAH 18.0328
621 5XC5 GTP 18.1818
622 5EE5 GTP 18.7134
623 4WZA ACP 18.8596
624 4WZA ADP 18.8596
625 1FP6 ADP 18.8596
626 3FVQ ATP 18.9415
627 1NF3 GNP 20.3125
628 4TMZ GSP 20.614
629 1HE1 GDP 22.2222
630 5E95 GDP 23.7113
631 2ZTS ADP 24.7012
632 3TBK ANP 25.4386
633 1IN4 ADP 25.4386
634 4QOS ADP 25.8772
635 5UWR GNP 25.9259
636 4D0G GTP 27.5362
637 5LTJ ADP 27.6316
638 5IRR GSP 28.0702
639 6FAA ADP 28.5088
640 2XZ9 PYR 28.5088
641 2Y65 ADP 30
642 1UPT GTP 31.6667
643 5UWQ GNP 31.8182
644 4A4Z ANP 33.3333
645 5XDR ADP 34.6491
646 1R4A GNP 37.2549
647 1FQJ GDP 40.4762
648 6B4K ANP 46.9298
Pocket No.: 2; Query (leader) PDB : 3IUY; Ligand: AMP; Similar sites found with APoc: 54
This union binding pocket(no: 2) in the query (biounit: 3iuy.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 3KO0 TFP None
2 4AVB ACO 1.31579
3 2B8T THM 1.75439
4 5MVR ADP 1.85185
5 3EWA ANP 2.19298
6 1AKY AP5 2.27273
7 1WWZ ACO 2.51572
8 1XP8 AGS 2.63158
9 6AU6 GDP 2.63158
10 1OE0 TTP 2.63158
11 2GDJ ANP 3.07018
12 5Z69 AGS 3.07018
13 1UJ2 C5P 3.07018
14 1NN5 2DT 3.25581
15 1NN5 ANP 3.25581
16 3FYH ADP 3.50877
17 3RC3 ANP 3.50877
18 1XMV ADP 3.50877
19 2QEN ADP 3.50877
20 2B4B COA 3.50877
21 4FCW ADP 3.50877
22 1W0O SIA 3.94737
23 3VMF GTP 3.94737
24 5J1S ATP 4.06504
25 2QQ0 THM 4.34783
26 1G41 ADP 4.38596
27 1CR1 TTP 4.38596
28 4MKG AP5 4.60829
29 2IXE ATP 4.82456
30 4QIJ 1HA 5.26316
31 4RD0 GDP 5.26316
32 5TVJ COA 5.70175
33 4YJ1 ADP 5.70175
34 5H7J GCP 5.70175
35 3QXC ATP 5.70175
36 1N62 MCN 5.70175
37 5W76 GDP 6.14035
38 1KK1 GNP 6.14035
39 5JBQ GDP 6.14035
40 4G5G GDP 6.14035
41 3U6K GDP 6.14035
42 2HCJ GDP 6.14035
43 5KSZ GCP 6.57895
44 1UKZ ADP 6.89655
45 5W7Q GDP 7.01754
46 2C78 GNP 7.01754
47 3CF6 SP1 7.78443
48 5KSP GDP 7.89474
49 2JLR ANP 9.64912
50 1YRO GDU 9.7561
51 1OFH ADP 12.069
52 3WY9 GDP 12.7193
53 5FG3 GDP 13.5965
54 5X40 ACP 17.5439
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