Receptor
PDB id Resolution Class Description Source Keywords
3IDB 1.62 Å EC: 2.7.11.11 CRYSTAL STRUCTURE OF (108-268)RIIB:C HOLOENZYME OF CAMP- DEPENDENT PROTEIN KINASE MUS MUSCULUS PKA CAMP SPR AFFINITY KINASE LINKER CRYSTAL STRUCTURERII HOLOENZYME ALTERNATIVE SPLICING ATP-BINDING CYTOPLASM LIPOPROTEIN MYRISTATE NUCLEOTIDE-BINDING NUCLEUS PHOSPHOPROTEIN SERINE/THREONINE-PROTEIN KINASE TRANSFERASE ACETYLATION CAMP-BINDING
Ref.: NOVEL ISOFORM-SPECIFIC INTERFACES REVEALED BY PKA RIIBETA HOLOENZYME STRUCTURES. J.MOL.BIOL. V. 393 1070 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:450;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MN A:401;
A:402;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3IDB 1.62 Å EC: 2.7.11.11 CRYSTAL STRUCTURE OF (108-268)RIIB:C HOLOENZYME OF CAMP- DEPENDENT PROTEIN KINASE MUS MUSCULUS PKA CAMP SPR AFFINITY KINASE LINKER CRYSTAL STRUCTURERII HOLOENZYME ALTERNATIVE SPLICING ATP-BINDING CYTOPLASM LIPOPROTEIN MYRISTATE NUCLEOTIDE-BINDING NUCLEUS PHOSPHOPROTEIN SERINE/THREONINE-PROTEIN KINASE TRANSFERASE ACETYLATION CAMP-BINDING
Ref.: NOVEL ISOFORM-SPECIFIC INTERFACES REVEALED BY PKA RIIBETA HOLOENZYME STRUCTURES. J.MOL.BIOL. V. 393 1070 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 3IDB - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 3IDB - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3IDB - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3IDB; Ligand: ANP; Similar sites found: 336
This union binding pocket(no: 1) in the query (biounit: 3idb.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3KA2 2NC 0.00708 0.42447 1.97044
2 2YW2 ATP 0.002676 0.42013 2.48447
3 4YHQ G10 0.007431 0.40891 3.0303
4 5GZ9 ANP 0.00000007018 0.60159 3.10559
5 2R7K AMZ 0.003466 0.41657 3.10559
6 1PK8 ATP 0.0003663 0.43707 3.14286
7 1AUX AGS 0.0001827 0.47967 3.53698
8 3I0O ADP 0.00008782 0.51786 3.72671
9 5IQD RIO 0.00008844 0.49625 3.72671
10 5IQD GNP 0.00008212 0.49625 3.72671
11 3K5I ADP 0.007153 0.40182 3.72671
12 4OCJ NDG 0.00004048 0.51105 4
13 4R78 AMP 0.000001859 0.47966 4.34783
14 4U98 ACP 0.0006211 0.46063 4.34783
15 3QV9 QV7 0.02984 0.40302 4.34783
16 4OCV ANP 0.00008651 0.46278 4.57143
17 5IH1 6BQ 0.002779 0.44199 4.63576
18 5IH1 GDP 0.002779 0.44199 4.63576
19 4DFU QUE 0.008998 0.42851 4.65839
20 5I35 ANP 0.00000306 0.50401 4.85714
21 4AZW ATP 0.00002865 0.4837 4.85714
22 3RE4 TO1 0.000004065 0.58317 4.96894
23 1ZP9 ATP 0.000002095 0.49667 4.96894
24 1ZTH ADP 0.0000007796 0.49473 4.96894
25 1W2D ADP 0.0004943 0.48113 4.96894
26 3AKK ADP 0.00009174 0.45908 4.96894
27 2VPQ ANP 0.0005417 0.44181 4.96894
28 3WVR AMP 0.0001103 0.43817 4.96894
29 5K2M ADP 0.0009221 0.43415 4.96894
30 1W2D 4IP 0.001004 0.40576 4.96894
31 5M12 7D0 0.01428 0.40556 4.96894
32 2HGS ADP 0.004158 0.4054 4.96894
33 1E4E ADP 0.001243 0.41591 5.53936
34 2IF8 ADP 0.00002703 0.55858 5.59006
35 3TDV GDP 0.000008397 0.53937 5.59006
36 3X01 AMP 0.0005084 0.49478 5.59006
37 3UDZ ADP 0.00002354 0.47904 5.59006
38 1IOW ADP 0.0009031 0.44843 5.59006
39 1IOW PHY 0.0009031 0.44843 5.59006
40 2IO8 ADP 0.0007432 0.43803 5.59006
41 3VPD ANP 0.0006429 0.43414 6.04982
42 4GYI ADP 0.00001557 0.54723 6.21118
43 4AXD ANP 0.0000456 0.4145 6.21118
44 2PUL ACP 0.00003372 0.51835 6.28571
45 4UUW AMP 0.003656 0.40246 6.28571
46 5MW8 ATP 0.00001113 0.51115 6.8323
47 1EHI ADP 0.0007828 0.44713 6.8323
48 5VZ0 ADP 0.0001544 0.43851 6.8323
49 3ETH ATP 0.003452 0.40524 6.8323
50 4OAV ACP 0.000000005537 0.59946 6.85714
51 1T36 ADP 0.003865 0.41311 6.85714
52 5W2I I3P 0.00006986 0.48048 7.393
53 5W2I ADP 0.00006986 0.48048 7.393
54 4IX4 ADP 0.00000334 0.51956 7.42857
55 3DNT ATP 0.000256 0.45716 7.45342
56 4ANW O92 0.001367 0.43798 7.45342
57 2Q7D ANP 0.0004489 0.42733 7.45342
58 2GCG DGY 0.02362 0.40247 7.45342
59 2PYW ADP 0.000006642 0.50906 8.07453
60 4LRJ ANP 0.000009216 0.48217 8.07453
61 4LO2 GAL BGC 0.007593 0.42134 8.07453
62 3WO0 ALA 0.005104 0.41943 8.07453
63 4FE2 ADP 0.007704 0.41844 8.07453
64 2VQD AP2 0.0005097 0.43449 8.28571
65 4O1P ANP 0.00000001728 0.59067 8.69565
66 4CS9 AMP 0.006438 0.42326 8.69565
67 5C1P DAL DAL 0.001997 0.42197 8.69565
68 5C1P ADP 0.0003009 0.41455 8.69565
69 4ZS4 ATP 0.00006244 0.46648 9.12052
70 1I7L ATP 0.0002588 0.44872 9.31677
71 4UWH JXM 0.001512 0.44751 9.31677
72 1XDN ATP 0.01248 0.40462 9.31677
73 5TT6 ATP 0.001979 0.42213 9.71429
74 1IA9 ANP 0.00004302 0.50217 9.93789
75 1GSA ADP 0.00005391 0.483 9.93789
76 4PU5 ANP 0.0001815 0.46133 9.93789
77 4LH7 1X8 0.002045 0.45853 9.93789
78 3ORQ ADP 0.003524 0.41501 9.93789
79 3TM0 ANP 0.0003145 0.40969 9.93789
80 3TM0 B31 0.0003404 0.40434 9.93789
81 3PDT ADP 0.0002828 0.48149 10.1818
82 5LXT ACP 0.0004562 0.44487 10.559
83 3W0O ADP 0.0001232 0.43322 11.1801
84 3W0O HY0 0.0001232 0.43322 11.1801
85 3VPC ADP 0.0002559 0.45939 11.3475
86 3VPB ADP 0.00009483 0.45914 11.3475
87 3Q60 ATP 0.00003999 0.46204 11.4286
88 1TQP ATP 0.00001282 0.50064 11.8012
89 5IGI GMP 0.002965 0.42857 11.8012
90 5IGI ZIT 0.003151 0.42857 11.8012
91 3TPV ADE 0.006105 0.40811 11.8012
92 2BKK ADP 0.00007964 0.43916 11.8343
93 2AQX ATP 0.0007259 0.43258 12.4224
94 4XYM A12 0.001208 0.4153 12.4224
95 4O4F ATP 0.0008902 0.43656 12.5
96 4O4F IHP 0.000978 0.43656 12.5
97 5CKW ANP 0.0000009251 0.4944 12.8571
98 5C4L 4XR 0.00001125 0.52535 13.0435
99 5C4L SIS 0.0002695 0.46662 13.0435
100 5TDF ADP 0.0008975 0.42514 13.0435
101 3VOT ADP 0.0004689 0.40942 13.1429
102 5DMZ ADP 0.000000008939 0.67204 14
103 4OH4 ANP 0.000000004252 0.68644 14.4144
104 5LPZ ADP 0.00000001974 0.58762 14.759
105 2QLU ADE 0.0000005544 0.65965 15.2866
106 4IJP 1EH 0.0000001535 0.57239 15.4286
107 4OUC 5ID 0.00000002298 0.56064 15.528
108 4I94 ANP 0.00000001071 0.58562 15.6667
109 2RIO ADP 0.000000002229 0.61345 16
110 5LPB ADP 0.000000103 0.52094 16.2162
111 3HAV ATP 0.0002405 0.46202 17.3913
112 3LXI CAM 0.02747 0.40427 17.7143
113 2CFM AMP 0.002127 0.45009 18.6335
114 4WW7 AMP 0.00001047 0.50636 18.7739
115 4CYI ATP 0.000005557 0.51013 18.8571
116 2CSN CKI 0.00000000822 0.64861 19.1919
117 3VHE 42Q 0.0000008138 0.50142 19.7143
118 4YZC STU 0.00000002513 0.64889 20.5714
119 5C03 AGS 0.00000779 0.49478 21.345
120 4Y0X ADP 0.000001143 0.51291 22
121 2PZI AXX 0.00002163 0.54041 22.8571
122 4WOV 3SM 0.0001202 0.50484 23.0284
123 4Q5H ANP 0.000001952 0.56765 23.6842
124 3HMO STU 0.0000009319 0.58945 25.4386
125 4JR7 GNP 0.00000000002385 0.69144 26
126 4CRL C1I 0.000002965 0.55372 26.8473
127 1Q8Y ADP 0.00000001921 0.60697 26.8571
128 1Q8Y ADE 0.0000003838 0.49405 26.8571
129 4IDT T28 0.000000001626 0.71528 27.1429
130 3VRY B43 0.00001137 0.49397 27.1429
131 5BVE 4VG 0.00000001585 0.69095 27.4238
132 5N87 N66 0.0000008019 0.5818 27.476
133 5KO1 6UY 0.00000247 0.50225 27.5618
134 1U5R ATP 0.00000001397 0.67267 27.5862
135 5MY8 RXZ 0.00000282 0.54044 27.7143
136 4E93 GUI 0.00000007455 0.52384 27.7143
137 3C1X CKK 0.0001404 0.45997 27.7143
138 4BTK DTQ 0.0000001958 0.5534 27.8932
139 3UIM ANP 0.000000006907 0.60718 27.9141
140 5UIU 8CG 0.0000003852 0.58562 28.1734
141 5T8O 76Z 0.00000003799 0.62755 28.3668
142 4H3Q ANP 0.00000008936 0.59728 28.5714
143 4H3P ANP 0.00000005137 0.57582 28.5714
144 3PP0 03Q 0.0000003134 0.54296 28.6982
145 4XH0 ADP 0.000002823 0.61436 28.8571
146 3LXN MI1 0.000000001066 0.6549 28.9308
147 4QTB 38Z 0.0000006955 0.5726 29.1429
148 3KMW ATP 0.0001411 0.49 29.1513
149 1VJY 460 0.000000005991 0.6671 29.3729
150 3H9R TAK 0.000003341 0.46247 29.697
151 4UX9 ANP 0.0000000004244 0.71106 29.7143
152 3GNI ATP 0.0000002288 0.59419 29.7143
153 2H8H H8H 0.00000008047 0.56465 29.7143
154 4BKJ STI 0.001272 0.43012 29.8413
155 2B9J ADP 0.000000004095 0.69698 30
156 2B9I ADP 0.000000007611 0.67516 30
157 2B9H ADP 0.000000009613 0.60954 30
158 3E8N VRA 0.00000005738 0.46339 30.2053
159 3E8N ATP 0.00000005738 0.46339 30.2053
160 5HCY 60D 0.000001609 0.57984 30.2115
161 5EOB 5QQ 0.00003697 0.52984 30.4075
162 5LXC 7AA 0.0000000003945 0.62155 30.5714
163 2WU6 DKI 0.00000004447 0.60973 30.5714
164 2B9F ADP 0.000000009427 0.59978 30.5714
165 3OFM 4B0 0.00000008725 0.53367 30.5714
166 4D2S DYK 0.000001018 0.495 30.6338
167 2PVN P63 0.000000001487 0.60596 30.6818
168 4NFN 2KC 0.000008408 0.54587 30.7443
169 5W4W 9WG 0.0000368 0.50344 31.1178
170 4KBA 1QM 0.00006025 0.45203 31.1178
171 4GJ3 0XP 0.00000001953 0.64287 31.1258
172 4P5Z Q7M 0.00002347 0.52136 31.1429
173 1OPK P16 0.00001126 0.4574 31.1429
174 3PE2 E1B 0.00000005757 0.64718 31.1573
175 3ALN ANP 0.00000003234 0.63055 31.1927
176 4CLI 5P8 0.000004767 0.55894 31.1927
177 5X8I SQZ 0.0000000006118 0.64066 31.2139
178 4E1Z 0MX 0.00000005779 0.60506 31.2715
179 1CM8 ANP 0.000000006821 0.59584 31.4286
180 5JGA 6KC 0.0000004053 0.58884 31.4286
181 3LXK MI1 0.00000002229 0.5762 31.4985
182 3KRR DQX 0.00000001852 0.69032 31.5254
183 3NW7 LGV 0.00002537 0.52928 31.5961
184 5DBX ANP 0.000001042 0.49838 31.7073
185 4F9C 0SX 0.000000004894 0.59822 31.7143
186 4NST ADP 0.0000000365 0.57991 31.7143
187 4IZY 1J2 0.000004274 0.5398 31.7143
188 4U44 3D9 0.00000007214 0.56429 31.9277
189 1Y57 MPZ 0.0000003461 0.57311 32
190 1OUK 084 0.000268 0.51816 32
191 5HVJ ANP 0.00000003196 0.72229 32.0635
192 3LQV ADE 0.003341 0.4373 32.1739
193 5BYZ 4WE 0.00001034 0.5269 32.1839
194 3KRL KRL 0.000005084 0.51813 32.2388
195 4Y93 746 0.00001672 0.50831 32.2857
196 4LOO SB4 0.0001195 0.44683 32.2857
197 2OO8 RAJ 0.001815 0.41579 32.4921
198 4YLL 4E3 0.000001611 0.54565 32.5714
199 4Y8D 49J 0.0000002708 0.60593 32.6471
200 1K3A ACP 0.000002372 0.49069 32.7759
201 3ORK AGS 0.0000001793 0.56529 32.7974
202 4Y85 499 0.0000007474 0.5209 32.8313
203 4NM5 ADP 0.000589 0.4724 32.8571
204 5TO8 7FM 0.00005422 0.50691 32.9787
205 4AT3 LTI 0.00002254 0.45769 33.1104
206 4WHZ 3NL 0.000002531 0.57658 33.1429
207 3TTI KBI 0.0000001701 0.5451 33.1429
208 3PTG 932 0.0000008786 0.49119 33.1429
209 5EFQ ADP 0.00000003014 0.58401 33.4294
210 1O9U ADZ 0.0000002167 0.6877 34
211 5AWM ANP 0.00000001826 0.54737 34
212 3PLS ANP 0.00000008767 0.55811 34.2282
213 2JLD AG1 0.000000003795 0.55783 34.2857
214 3E7O 35F 0.00002692 0.51093 34.2857
215 4QMN DB8 0.000004233 0.55053 34.5161
216 3F7Z 34O 0.00000001517 0.59178 34.5714
217 3ZRM ZRM 0.000001035 0.52267 34.5714
218 5AX9 4KT 0.00000001933 0.5861 34.7403
219 4AUA 4AU 0.0000001258 0.55243 34.8534
220 4ASE AV9 0.00001076 0.52045 35.1275
221 4AU8 Z3R 0.00000003882 0.68203 35.1351
222 4YZN 4K5 0.0000000003597 0.69572 35.1916
223 4EWH T77 0.0000002111 0.54004 35.2727
224 5NKB 8ZT 0.000009514 0.41817 35.2941
225 5JFS 6K0 0.000007466 0.54606 35.3896
226 3DAK ANP 0.0000002343 0.62531 35.5172
227 4YMJ 4EJ 0.00000007985 0.6966 35.5263
228 2HK5 1BM 0.000006149 0.50943 35.5556
229 2BPM 529 0.000000009409 0.46898 35.5987
230 4XV1 904 0.000005002 0.54397 35.6164
231 5HES 032 0.000001476 0.53963 35.8306
232 5H2U 1N1 0.00006246 0.45703 35.9551
233 3O0G 3O0 0.000000005399 0.5964 35.9589
234 1UNH IXM 0.0000000172 0.55733 35.9589
235 2F57 23D 0.000002264 0.49641 36
236 3GGF GVD 0.000000001583 0.72659 36.2126
237 5DA3 58V 0.0000008229 0.61712 36.2264
238 2A19 ANP 0.0000002062 0.64654 36.2676
239 2XVD AS6 0.000006008 0.53309 36.4238
240 4X7Q 3YR 0.0000000003619 0.73419 36.5385
241 3GC8 B45 0.000003202 0.53915 36.5714
242 5M06 ADP 0.000004672 0.48357 36.5942
243 4CFU 2WC 0.000000008996 0.69137 36.6337
244 5HX8 66P 0.00000001834 0.5899 36.755
245 4G31 0WH 0.00001058 0.44247 36.7893
246 4BCQ TJF 0.0000001319 0.51785 36.8771
247 4BCM T7Z 0.000001206 0.46844 36.8771
248 2XMY CDK 0.0000001167 0.65446 36.9128
249 4EUU BX7 0.00000002021 0.63228 36.9906
250 4BCN T9N 0.000000004016 0.71865 37
251 4CQE CQE 0.000004006 0.53507 37.0504
252 4M69 ANP 0.000001336 0.53724 37.0607
253 3TKI S25 0.000000007621 0.69585 37.1517
254 2HY0 306 0.00000009199 0.65369 37.2671
255 4JDI ANP 0.000000002899 0.67536 37.2832
256 4AG8 AXI 0.000001029 0.46403 37.3418
257 5LMK 6ZK 0.000001297 0.50305 37.3737
258 3SLS ANP 0.0000000259 0.62686 37.5
259 5U6C 7YS 0.000000691 0.554 37.7778
260 3IGO ANP 0.000001954 0.54815 38
261 2Y6O 1N1 0.00002319 0.5031 38.1443
262 4K33 ACP 0.000000004628 0.62145 38.1538
263 2OFV 242 0.0000207 0.52071 38.2671
264 2PVF ACP 0.0000000007895 0.72959 38.3234
265 5CEO 50D 0.000006056 0.49437 38.3333
266 5JKG 6LF 0.00001109 0.53556 38.5852
267 4BHN BH9 0.000000001432 0.64971 38.6228
268 5HQ0 LZ9 0.000000002361 0.64274 38.7417
269 3GQI ACP 0.000000004243 0.6105 38.9571
270 5MJA 7O3 0.000005251 0.48149 39.0164
271 5VC5 96M 0.000002245 0.54902 39.1003
272 3DLS ADP 0.0000000006205 0.61431 39.1045
273 5TA6 79D 0.00006315 0.48817 39.1061
274 1V0O INR 0.000000002479 0.68736 39.2361
275 1U59 STU 0.000000001271 0.70984 39.3728
276 4FL3 ANP 0.0000003089 0.58173 39.7143
277 4XLI 1N1 0.00000562 0.48685 39.9254
278 2YAB AMP 0.0000000002454 0.66998 40
279 2WQN ADP 0.000004467 0.57313 40
280 3KN5 ANP 0.00000001033 0.5677 40
281 3EKK GS2 0.000006074 0.54537 40.0651
282 4BFM ANP 0.000000002087 0.64572 40.1198
283 5USZ SKE 0.0000004387 0.57879 40.1384
284 5EKO N17 0.0004294 0.44595 40.2857
285 4G17 0VN 0.000006583 0.47583 40.303
286 3BU5 ATP 0.00000003349 0.58228 40.5229
287 3SXF BK5 0.000003166 0.55427 40.5714
288 3RI1 3RH 0.0000002179 0.58914 40.5751
289 3SXS PP2 0.000001111 0.56483 40.6716
290 4CSV STI 0.0002141 0.45838 40.7273
291 3G5D 1N1 0.0000008802 0.60482 40.9091
292 4U0I 0LI 0.00003896 0.50238 40.9524
293 2X2M X2M 0.00000007967 0.59093 41.0828
294 3C0G 3AM 0.0000000395 0.54137 41.1429
295 3HZT J60 0.0000000696 0.52705 41.1429
296 5VCV 1N1 0.0000001249 0.59405 41.1576
297 5UR1 YY9 0.00004856 0.51299 41.1576
298 4N70 2HX 0.000000008723 0.68701 41.1585
299 4TWP AXI 0.000001378 0.58427 41.3284
300 3FHR P4O 0.0000001001 0.61719 41.369
301 5FBN 5WF 0.000007049 0.53929 41.6974
302 3FC2 IBI 0.0001297 0.51485 41.791
303 3SRV S19 0.0000000005859 0.62999 41.8773
304 2V7O DRN 0.000000001461 0.56601 41.9643
305 4F4P 0SB 0.0000004752 0.6206 42.4908
306 4I6H 1C8 0.00003559 0.51138 42.5325
307 3GC0 AMP 0.000004456 0.48135 42.5532
308 1BYG STU 0.000000008152 0.57944 42.8058
309 2J7T 274 0.00002449 0.50918 43.0464
310 5DEY 59T 0.000008077 0.55873 43.0976
311 3CY2 MB9 0.000000001744 0.66754 43.3121
312 2WEL K88 0.0000004748 0.45946 43.4251
313 5DH3 5BS 0.000000188 0.5674 43.4921
314 2X4Z X4Z 0.000031 0.51156 43.5811
315 5IH9 6BF 0.0000002775 0.60174 43.5821
316 3M2W L8I 0.0000000005713 0.60822 44.1472
317 5DRB 5FJ 0.000002599 0.5734 44.3299
318 2VZ6 FEF 0.00000001019 0.69933 44.7284
319 4KS7 X4Z 0.00001113 0.51116 44.863
320 1ZY5 ANP 0.0000006361 0.5251 44.8845
321 4L9I 8PR 0.0000005188 0.52776 45.7143
322 4A4X JUP 0.000008192 0.52334 46.2366
323 5A6N U7E 0.0000002861 0.55725 46.2898
324 2WEI VGG 0.00002119 0.46184 46.3415
325 1PHK ATP 0.000000000005852 0.73007 46.6443
326 4WNP 3RJ 0.00000000121 0.59714 47.0383
327 4USF 6UI 0.00004425 0.48868 47.0395
328 2VN9 GVD 0.00000001091 0.53379 47.1761
329 5UOX 8GY 0.000000002862 0.64859 47.6015
330 4FG8 ATP 0.00000001402 0.61458 47.9365
331 2ZV2 609 0.000000001405 0.75258 47.9866
332 2YAK OSV 0.00000002467 0.6362 48.0702
333 3OCP CMP 0.006545 0.42615 48.2014
334 4WNK 453 0.000000005753 0.663 48.5714
335 2XK9 XK9 0.000001324 0.57238 48.7578
336 5JZJ AN2 0.0000000003061 0.64085 48.8215
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