Receptor
PDB id Resolution Class Description Source Keywords
3IAI 2.2 Å EC: 4.2.1.1 CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE TUMOR-ASSOC HUMAN CARBONIC ANHYDRASE IX HOMO SAPIENS CARBONIC ANHYDRASES TRANSMEMBRANE PROTEINS CELL MEMBRANE PROJECTION DISULFIDE BOND GLYCOPROTEIN LYASE MEMBRANE BINDING NUCLEUS PHOSPHOPROTEIN TRANSMEMBRANE
Ref.: CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF THE TUMOR-ASSOCIATED HUMAN CARBONIC ANHYDRASE IX. PROC.NATL.ACAD.SCI.USA V. 106 16233 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AZM A:263;
B:263;
C:263;
D:263;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
222.245 C4 H6 N4 O3 S2 CC(=O...
GLU ALA SER PHE PRO A:257;
 Part of Protein;
 none;
 submit data
n/a n/a
GOL A:300;
A:301;
A:302;
A:303;
A:304;
A:305;
A:307;
B:300;
B:301;
B:302;
B:303;
B:304;
B:306;
C:300;
C:301;
C:302;
C:303;
C:304;
D:300;
D:301;
D:302;
D:303;
D:304;
D:306;
D:307;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
 submit data
92.094 C3 H8 O3 C(C(C...
NAG NAG BMA MAN MAN F:1;
E:1;
G:1;
H:1;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
 submit data
n/a n/a
PO4 A:600;
A:601;
B:600;
C:600;
D:600;
 Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
none;
 submit data
94.971 O4 P [O-]P...
TRS A:501;
B:501;
C:501;
D:501;
 Invalid;
Invalid;
Invalid;
Invalid;
 none;
none;
none;
none;
 submit data
122.143 C4 H12 N O3 C(C(C...
ZN A:262;
B:262;
C:262;
D:262;
 Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
 none;
none;
none;
none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
6FE1 1.95 Å EC: 4.2.1.1 THREE DIMENSIONAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE IX I WITH BENZENESULFONAMIDE. HOMO SAPIENS LYASE
Ref.: NOVEL FLUORINATED CARBONIC ANHYDRASE IX INHIBITORS HYPOXIA-INDUCED ACIDIFICATION AND CLONOGENIC SURVIV CANCER CELLS. ONCOTARGET V. 9 26800 2018
Members (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 19 families.
1 6G9U Kd = 0.2 nM ETK C23 H27 F3 N2 O4 S2 c1cc(ccc1C....
2 6G98 Kd = 0.16 nM ER5 C27 H35 F3 N2 O4 S2 c1cc(ccc1C....
3 5FL6 Ki = 43.6 nM Y0R C13 H12 N4 O2 S2 Cc1ccc(cc1....
4 6FE0 Kd = 1.1 nM V90 C16 H23 F3 N2 O3 S2 C1CCCC(CCC....
5 5FL4 Ki = 101 nM 9FK C16 H12 N4 O2 S2 c1ccc2c(c1....
6 3IAI - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
7 6FE1 Kd = 0.05 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
8 5FL5 Ki = 6.4 nM 82E C13 H12 N4 O3 S2 COc1ccc(cc....
70% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 6G9U Kd = 0.2 nM ETK C23 H27 F3 N2 O4 S2 c1cc(ccc1C....
2 6G98 Kd = 0.16 nM ER5 C27 H35 F3 N2 O4 S2 c1cc(ccc1C....
3 5FL6 Ki = 43.6 nM Y0R C13 H12 N4 O2 S2 Cc1ccc(cc1....
4 6FE0 Kd = 1.1 nM V90 C16 H23 F3 N2 O3 S2 C1CCCC(CCC....
5 5FL4 Ki = 101 nM 9FK C16 H12 N4 O2 S2 c1ccc2c(c1....
6 3IAI - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
7 6FE1 Kd = 0.05 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
8 5FL5 Ki = 6.4 nM 82E C13 H12 N4 O3 S2 COc1ccc(cc....
50% Homology Family (638)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 3K34 - SUA C13 H14 N2 O3 S3 c1cc(ccc1N....
2 4XE1 Ki = 77.3 nM IL5 C7 H6 N2 O5 S2 c1cc2c(cc1....
3 5JG3 - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
4 4HT0 Kd = 10 nM V50 C12 H9 F4 N3 O2 S2 Cc1cc(nc(n....
5 1IF8 Kd = 230 pM SBS C19 H21 N3 O3 S C[C@@H](CN....
6 6ODZ Ki = 0.7 nM M8J C15 H18 N4 O5 S c1cc(ccc1N....
7 7JO2 Ki = 2.4 nM VFM C6 H10 N4 O3 S2 CC(C)C(=O)....
8 1I9L Kd = 3.3 nM INV C14 H13 F N2 O3 S c1cc(ccc1C....
9 6PGX Ki = 0.62 nM OJ4 C18 H24 N2 O8 S2 Te c1cc(ccc1O....
10 3VBD Ki = 8.6 nM 0FZ C16 H16 N2 O3 S COc1ccc2c(....
11 7JNX Ki = 63.4 nM VGS C7 H12 N4 O3 S2 CC(C)(C)C(....
12 3M5E Kd = 0.043 uM JDR C13 H13 Cl N4 O3 S2 CSc1nc(c(c....
13 6BBS - BZ1 C12 H21 N3 O5 S3 CCN[C@H]1C....
14 6FJJ Ki = 100 nM LSA C7 H5 N O3 S c1ccc2c(c1....
15 3P5A Ki = 0.95 nM IT2 C5 H9 N O S2 C1COCCN1C(....
16 2AW1 Ki = 43 nM COX C16 H14 N2 O3 S Cc1c(c(no1....
17 4M2W - ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
18 5J8Z Ki = 5 nM FC4 C20 H16 Cl N5 O4 S2 C[C@H](C(=....
19 4QTL Kd = 120 nM WWO C15 H15 F3 N2 O5 S2 c1ccc(cc1)....
20 6QFU Kd = 35 nM J0K C24 H29 Cl Ir N3 O4 S CC12C3([Ir....
21 5BYI Ki = 30.7 nM 4WA C12 H12 N4 O2 S c1cc(ccc1N....
22 6G6T Kd = 0.16 nM ENN C11 H14 Cl2 N2 O3 S CCCCNC(=O)....
23 4PYX Kd = 730 nM V90 C16 H23 F3 N2 O3 S2 C1CCCC(CCC....
24 5WLT Ki = 155.5 nM 86B C12 H20 N2 O4 S CC(C)NC[C@....
25 5FLT Kd = 1280 uM VJJ C13 H10 O3 c1ccc(cc1)....
26 4RIV - LSA C7 H5 N O3 S c1ccc2c(c1....
27 5NEA Ki = 0.05 nM 8V8 C10 H10 N2 O3 S Cc1ncc(o1)....
28 5EKM Kd = 0.48 uM TG5 C12 H19 N3 O3 S CCCCNCC(=O....
29 3MHC Ki = 11 nM ARZ C13 H18 N4 O3 S2 C1C2CC3CC1....
30 6T7U Ki = 0.5 nM X33 C5 H8 B10 N O2 S B1234B567B....
31 6YZJ - Q2Z C4 H6 B10 N O2 S B1234B567B....
32 5NXG Ki = 2.8 nM RA1 C13 H10 Cl N3 O5 S c1cc(ccc1N....
33 5L6K - QUK QVS 6H0 QUJ QVE n/a n/a
34 6B4D Ki = 0.78 uM 53X C15 H15 N3 O2 CCn1cc(c2c....
35 3M96 Kd = 0.06 uM E38 C15 H11 Br Cl N3 O3 S2 c1cc(c(cc1....
36 4ITP Ki = 54 nM 1GD C15 H16 N2 O3 S c1ccc(cc1)....
37 6CJV Ki = 300 nM RRY RRJ n/a n/a
38 2GD8 ic50 = 379 nM PO1 C19 H28 N2 O7 S2 C[C@]12CC[....
39 5G03 - OE2 C11 H14 Br N3 O5 S c1cc(c(cc1....
40 7JNV Ki = 53.8 nM VFJ C6 H10 N4 O3 S2 CCCC(=O)Nc....
41 4QSI Kd = 50 nM EWZ C16 H18 Cl N3 O4 S2 CC(C)(C)C1....
42 7K6T - VYV C15 H18 N4 O5 S2 c1ccc(cc1)....
43 1BNV Kd = 1.7 nM AL7 C14 H17 N3 O5 S3 CN[C@@H]1C....
44 1I9Q Kd = 3.9 nM IOF C14 H11 F3 N2 O3 S c1cc(ccc1C....
45 6IC2 Ki = 917.4 nM BBJ C11 H13 Br F N7 O4 S c1cc(c(cc1....
46 6RSZ - KJ5 C8 H7 F4 N O2 S CCc1c(c(c(....
47 2Q1Q Ki = 7 nM OSP C10 H14 N2 O4 S2 c1cc(ccc1N....
48 5LJT Ki = 1.2 nM A6N C15 H16 N4 O3 S c1ccc(cc1)....
49 1G0E - 4MZ C4 H6 N2 Cc1c[nH]cn....
50 4QIY Kd = 50 nM WWX C22 H21 F3 N2 O6 S2 c1ccc(cc1)....
51 2OSF Ki = 148 uM TH0 C6 H6 O2 S c1cc(c(cc1....
52 5BRV Kd = 0.96 nM 9TH C28 H31 Cl Ir N3 O4 S2 C[C-]12C3(....
53 6RW1 Ki = 1305 nM KL5 C15 H16 B N2 O3 S [B-]1(c2cc....
54 6SAC - 47J C6 H11 N3 Cc1cc(n(n1....
55 6D1L Ki = 7.6 nM FQV C10 H11 N O2 S Se CC#CC[Se]c....
56 5U0E Kd = 7.7 uM 7R4 C10 H9 N O S2 c1ccc(cc1)....
57 4PYY Kd = 59 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
58 6XXT Ki = 3.7 nM O42 C18 H19 N3 O4 S c1ccc(cc1)....
59 1G45 Kd = 2.3 nM FSB C14 H13 F N2 O3 S c1ccc(c(c1....
60 5FNK Kd = 1005 uM 5OO C9 H6 Cl2 O2 c1cc(c(cc1....
61 2NNO Kd = 0.4 uM M28 C9 H11 N O4 S c1cc(ccc1C....
62 4Q81 Ki = 950 uM 7MH C7 H9 N O S CC1=CC(=S)....
63 3CA2 - AMS C6 H7 Hg N2 O2 S c1cc(c(cc1....
64 4Q7P Ki = 48 uM 3MH C6 H7 N O S CC1=CC=CN(....
65 4YYT Kd = 418.3 nM S2O C8 H11 N O3 S c1cc(ccc1C....
66 5E2K Ki = 9.3 nM BX4 C12 H12 N2 O2 S c1cc(cc(c1....
67 3M2N - J74 C12 H12 Cl N5 O4 S c1cc(ccc1C....
68 6H3Q Ki = 47.3 nM FMH C10 H9 Cl N2 O2 S Se c1cc(ccc1c....
69 3OYS Ki = 9 nM OYS C14 H14 N2 O3 S c1ccc(cc1)....
70 6RVK Ki = 439 nM R29 C15 H16 B N2 O4 [B-]1(c2cc....
71 6H29 Ki = 2.4 uM FK8 C8 H9 N O2 c1ccc(cc1)....
72 3RYZ Kd = 2.4 nM RYZ C11 H9 F7 N2 O3 S c1cc(ccc1C....
73 4M2V - BZ1 C12 H21 N3 O5 S3 CCN[C@H]1C....
74 3S8X Kd = 0.07 uM E59 C13 H13 N3 O4 S2 CC1=CC(=O)....
75 5U0G - 7QY C12 H13 N O4 S COc1ccc(c(....
76 3K7K Kd ~ 8.86 nM KCS C H2 S3 C(=S)(S)S
77 3T83 Ki = 105 nM MG5 C15 H25 N O11 S CCC(=O)O[C....
78 3BL1 Ki = 2520 nM BL1 C16 H16 Cl N3 O3 S C[C@H]1Cc2....
79 5EH7 Kd = 330 uM 5O5 C8 H6 Cl2 N4 O c1cc(c(cc1....
80 4RUY Ki = 12.8 nM 3W6 C9 H13 N O3 S CCCOc1ccc(....
81 3MHO Kd = 0.32 uM J43 C12 H11 Cl N4 O3 S2 CSc1nc(c(c....
82 6UGN Ki = 763.5 nM Q77 C9 H10 N2 O3 S Cc1cc(c2c(....
83 6YZT Ki = 622 nM Q3E C5 H8 B10 N O2 S B1234B567B....
84 4YX4 Kd = 1073.4 nM FB2 C6 H7 N O2 S c1ccc(cc1)....
85 4N16 ic50 = 0.22 mM CHD C24 H40 O5 C[C@H](CCC....
86 3K2F Ki = 63 nM NKX C14 H20 N4 O12 S3 CCN([C@H]1....
87 2WEO Kd = 118 nM FBW C6 H6 F N O2 S c1cc(cc(c1....
88 6UGR Ki = 533.6 nM Q71 C7 H5 F N2 O3 S c1cc2c(cc1....
89 3PO6 - DT9 C12 H18 N2 O4 S C[C@H]1c2c....
90 3V7X Ki = 2.7 nM D7A C17 H20 N2 O5 S COc1ccc(cc....
91 3IBU Ki = 0.7 nM O48 C10 H23 N O3 S CCCCCCCCCC....
92 6S03 Ki = 17 nM KPW C25 H26 N6 O2 S Cc1cccc(n1....
93 1BNT Kd = 0.16 nM AL2 C13 H14 N2 O6 S3 COc1ccc(cc....
94 4YXU Kd = 57.4 nM 4JE C9 H13 N O2 S CCCc1ccc(c....
95 4Q09 Kd = 6.7 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
96 6RJJ - K5W C6 H5 F2 N O2 S c1cc(c(c(c....
97 5FLS Kd = 905 uM 6ZX C10 H9 Cl O2 C/C(=CC(=O....
98 3DCS Ki = 11.4 nM MZM C5 H8 N4 O3 S2 CC(=O)/N=C....
99 5TYA Kd = 32.9 uM 7QS C9 H7 N O2 S c1ccc(cc1)....
100 7K6J Ki = 50.8 nM VYY C16 H20 N4 O5 S2 Cc1ccc(cc1....
101 3RYV Kd = 86 nM RYV C9 H12 N2 O3 S CCNC(=O)c1....
102 2WEJ Kd = 839 nM FB2 C6 H7 N O2 S c1ccc(cc1)....
103 6WQ4 Ki = 368.5 nM U7A C29 H34 N4 O3 S c1ccc(cc1)....
104 3MYQ Kd = 0.03 uM E27 C18 H13 Cl N4 O3 S2 c1ccc2c(c1....
105 6SD7 - SXG C12 H3 F9 N2 O4 S2 c1(c(c(c(c....
106 6YO2 - P6Q C5 H8 B10 N O2 S B12B34B156....
107 4ZWZ - 510 C12 H22 N2 O12 S2 COC(=O)[C@....
108 6RZX Ki = 7 nM KPQ C4 H2 F9 N O2 S C(C(C(F)(F....
109 4Q6D Kd = 0.0435 uM WW3 C12 H18 N4 O2 S c1cc(ccc1/....
110 3V5G Ki = 74 nM 0F3 C6 H9 N3 O4 S2 c1cc(ccc1N....
111 1EOU ic50 = 36 nM SMS C9 H15 N O10 S2 CC1(O[C@H]....
112 4RFC Ki = 5.7 nM 3O1 C15 H24 N2 O5 S CC(C)(C)OC....
113 6H33 Ki = 0.6 nM FKQ C18 H20 N2 O4 S c1ccc(cc1)....
114 5VGY Kd = 65.5 uM 9AA C12 H14 N2 O4 S COc1ccc(c(....
115 1BN4 Kd = 0.49 nM AL9 C12 H14 N2 O5 S3 COc1ccc(cc....
116 6T9Z Ki = 1.178 nM MYW C5 H8 B9 N O2 S B123B45B16....
117 5NY3 Ki = 33.9 nM 9E8 C15 H16 Cl N3 O3 S c1cc(ccc1C....
118 1G4O Kd = 5.6 nM BSB C14 H14 N2 O3 S c1ccc(cc1)....
119 6S9G - L1Q C9 H9 F4 N O2 S CCCc1c(c(c....
120 6YZO - Q3K C8 H14 B10 N O2 S B1234B567B....
121 5SZ3 Ki = 2.5 nM 72H C15 H12 N2 O2 S c1ccc2c(c1....
122 6YZQ Ki = 870.1 nM Q3Q C6 H10 B10 N O2 S B1234B567B....
123 4RUZ - 3W8 C8 H11 N O3 S CCOc1ccc(c....
124 3KIG ic50 = 245 nM DA4 C8 H7 N O2 S C#Cc1cccc(....
125 3EFI - TRP C11 H12 N2 O2 c1ccc2c(c1....
126 5SZ5 - 72E C13 H13 N O2 S Cc1ccccc1c....
127 3N0N Ki = 50 nM P9B C13 H8 F5 N3 O3 S c1cc(ccc1N....
128 4Q06 Kd = 22 nM V90 C16 H23 F3 N2 O3 S2 C1CCCC(CCC....
129 6CEH Ki = 36.5 nM EZ1 C9 H11 N O2 S Se C=CC[Se]c1....
130 2X7T Ki = 232 nM WZB C20 H30 N2 O6 S2 CCc1cc2c(c....
131 4Z1J Ki = 7.7 nM 4KC C16 H16 N2 O3 S c1ccc2c(c1....
132 5U0F Kd = 3.4 uM 7R1 C12 H13 N O3 S2 COc1ccc(c(....
133 6OE0 Ki = 1.2 nM M8S C17 H22 N4 O5 S c1cc(ccc1N....
134 3T5Z Ki = 8.96 uM B09 C7 H9 N O3 S CONS(=O)(=....
135 4FIK - TH0 C6 H6 O2 S c1cc(c(cc1....
136 7JOB Ki = 15.7 nM VGV C9 H14 N4 O3 S2 C1CCC(CC1)....
137 4E3D ic50 = 5 mM GTQ C7 H6 O4 c1cc(c(cc1....
138 1G46 Kd = 1.6 nM F2B C14 H12 F2 N2 O3 S c1cc(c(c(c....
139 5JEP - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
140 6R6J Kd = 0.12 nM JTW C15 H15 Cl N2 O6 S2 c1ccc(cc1)....
141 6Z04 - Q3W C6 H10 B9 N O2 S B123B45B16....
142 3IBL Ki = 14.6 nM O59 C8 H20 N2 O6 S2 C(CCCCOS(=....
143 6UGQ - Q7A C7 H5 Cl N2 O3 S c1cc2c(c(c....
144 6YZL - Q3T C3 H4 B10 N O2 S B1234B567B....
145 5CLU Ki = 78 uM S8A C9 H7 N O5 S c1ccc2c(c1....
146 6RVL Ki = 1148 nM KKE C14 H14 B N2 O3 S [B+]1(c2cc....
147 5FLR Kd = 1.35 uM XCZ C5 H7 N3 O2 S Cc1ccnc(n1....
148 5EKH Kd = 1.11 uM 5RD C11 H18 N2 O2 S CCCCNCc1cc....
149 5JG5 - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
150 6GOT Ki = 0.4 nM F6W C14 H15 N O2 S2 c1ccc(cc1)....
151 6ROB - KBZ C7 H6 N2 O2 S c1cc(ccc1C....
152 5ULN Ki = 14.2 nM 8JS C13 H12 F N3 O2 S2 c1cc(ccc1N....
153 1IF6 - FBU C6 H5 F2 N O2 S c1c(cc(cc1....
154 2O4Z Ki = 566 nM HSW H4 N2 O3 S NS(=O)(=O)....
155 3T84 Ki = 106 nM SG6 C8 H15 N O9 S CC(=O)O[C@....
156 4Q78 - 25X C3 H5 B10 N2 O2 S B1234B567B....
157 7JNW Ki = 75.1 nM VFM C6 H10 N4 O3 S2 CC(C)C(=O)....
158 5EH8 Kd = 791 uM 5O6 C11 H12 O3 C/C(=CC(=O....
159 6C7X Ki = 65.2 nM EO7 C10 H13 Cl N6 O6 S c1nc2c(nc(....
160 7K6Z - VZD C15 H17 F N4 O5 S2 c1cc(ccc1N....
161 5JGT - EVI C3 H4 N2 O2 S2 c1csc(n1)S....
162 2WD2 - MS5 C18 H22 N2 O5 S COc1cccc(c....
163 1CRA - TRI C2 H3 N3 c1[nH]cnn1
164 6QL1 Kd = 15 nM V50 C12 H9 F4 N3 O2 S2 Cc1cc(nc(n....
165 6MBY - FER C10 H10 O4 COc1cc(ccc....
166 5W8B - A57 C17 H26 N3 Cc1cc([n+]....
167 4KNJ Kd = 11.1 nM E1F C12 H10 Cl N3 O3 S2 c1cnc(nc1)....
168 1OKM - SAB C11 H17 N3 O3 S c1cc(ccc1C....
169 3RZ5 Kd = 13 nM RZ5 C12 H18 N2 O3 S CCCCCNC(=O....
170 4Q7S Ki = 38 uM 2YU C6 H7 N O S CC1=CC(=S)....
171 6U4T Ki = 78.7 nM PX7 C8 H8 N2 O3 S CN1c2ccccc....
172 3N4B Ki = 96 nM WWZ C13 H12 F N3 O3 S c1cc(ccc1N....
173 3M1K Ki = 4.1 uM BEW C5 H6 N O S c1cc[n+](c....
174 1CIM Ki = 1.52 nM PTS C8 H12 N2 O4 S3 C[C@H]1C[C....
175 4MLT Ki = 1.4 mM TM4 C6 H6 O2 S CC1=C(C(=S....
176 3HKN Ki = 4.51 uM Z3K Z3L n/a n/a
177 4RFD Ki = 8.9 nM 3O5 C10 H16 N2 O3 S c1cc(ccc1O....
178 2GEH Ki = 28 uM NHY C H4 N2 O2 C(=O)(N)NO
179 4ZX1 - 5L3 C13 H24 N2 O11 S2 CC(=O)O[C@....
180 4E49 Ki = 7.7 uM RCO C6 H6 O2 c1cc(cc(c1....
181 6UFB Ki = 4.4 nM Q64 C17 H16 N2 O4 S CC(=O)/C(=....
182 6EDA Ki = 0.2 uM J3V C14 H11 F3 N4 O6 S c1cc(ccc1C....
183 3M3X Kd = 0.15 uM JS7 C13 H15 N5 O5 S COc1c(c(nc....
184 6B5A - CQS C15 H17 N7 O3 S c1cc(ccc1C....
185 3B4F Ki = 7.2 nM TUO C15 H14 N4 O3 S c1ccc(cc1)....
186 5SZ0 Ki = 0.8 nM 72D C12 H11 N O2 S c1ccc(cc1)....
187 4E3G Ki = 10.6 uM PHB C7 H6 O3 c1cc(ccc1C....
188 4M2U Ki = 9.1 nM ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
189 6EEO Ki = 0.37 uM J6V C14 H13 F N4 O6 S Cc1cc(ccc1....
190 4MDL Ki = 1.16 uM 25Y C3 H5 B10 N2 O2 S B1234B567B....
191 4R5B Ki = 185 nM 3J4 C10 H20 N2 O10 S2 C1CN(C[C@@....
192 4Q99 Ki = 0.52 uM HT4 C7 H8 O S Cc1ccc(c(c....
193 6WQ5 Ki = 57 nM U7G C26 H34 N4 O4 S c1ccc(cc1)....
194 5N0E Ki = 3.6 nM 8F3 C22 H20 N2 O5 S c1ccc(cc1)....
195 4Z1E Ki = 5.7 nM DF5 C17 H15 N2 O4 S COc1ccc2c(....
196 5WEX Ki = 66.3 nM 8JS C13 H12 F N3 O2 S2 c1cc(ccc1N....
197 1BNQ Kd = 0.32 nM AL4 C11 H19 N3 O5 S3 CCN[C@H]1C....
198 1XPZ Kd = 84 nM 4TZ C16 H14 N6 O3 S c1cc(ccc1C....
199 6H34 Ki = 0.5 nM FKK C18 H20 F N3 O3 S c1cc(ccc1C....
200 6SBH - BE7 C7 H5 Cl Hg O2 c1cc(ccc1C....
201 6QL2 Kd = 1.1 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
202 4Z1N Ki = 5.89 nM 4KD C18 H20 N2 O5 S COc1cc2c(c....
203 6H2Z Ki = 0.5 nM FKE C18 H20 N2 O3 S c1ccc(cc1)....
204 2NNV Kd = 0.03 uM M29 C11 H15 N O4 S CCOC(=O)CC....
205 4Q8X Ki = 270 uM 7FH C6 H4 F3 N O S C1=CC(=S)N....
206 4KV0 Ki = 12 nM MB7 C13 H14 N4 O5 S2 Cc1ccc(cc1....
207 1G1D Kd = 0.36 nM FSB C14 H13 F N2 O3 S c1ccc(c(c1....
208 4R5A Ki = 2 nM 3J4 C10 H20 N2 O10 S2 C1CN(C[C@@....
209 5SZ7 - 72H C15 H12 N2 O2 S c1ccc2c(c1....
210 4PZH Kd < 10 nM V13 C8 H7 F4 N O5 S2 C(CS(=O)(=....
211 4Q07 Kd = 7.3 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
212 3N3J Ki = 3.3 nM WWV C16 H19 N3 O3 S CC(C)c1ccc....
213 3CAJ Ki = 8 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
214 5DOH Kd = 32 nM 5DU C17 H17 F3 N2 O3 S2 c1ccc2c(c1....
215 5TI0 Ki = 61 uM 7CZ C7 H6 O S C1=CC=C(C(....
216 6SDJ - J3K C3 H9 N O C[C@H](CN)....
217 4RIU - 3QR C16 H18 N4 O9 S c1cc2c(cc1....
218 3NI5 Ki = 28 nM C1H C13 H15 N5 O9 S3 c1cc(cc(c1....
219 6YZX Ki = 29.48 nM Q3H C8 H14 B9 N O2 S B123B45B16....
220 3SBH Kd = 0.22 uM E65 C14 H15 N3 O3 S2 Cc1cc(nc(n....
221 6SAS - 463 C9 H12 N2 O CC(=O)Nc1c....
222 4QY3 Ki = 0.15 uM 3G1 C14 H12 O3 S c1ccc(cc1)....
223 3D9Z Ki = 2 nM D9Z C8 H6 Cl N3 O2 S2 c1ccc(c(c1....
224 5MJN Ki = 2.9 nM 7O8 C11 H10 Cl N O2 S3 c1cc(ccc1C....
225 6RG3 Ki = 8.1 nM K1W C18 H21 N3 O3 S c1ccc(cc1)....
226 6QFV Kd = 49 nM J0N C24 H29 Cl Ir N3 O3 S CC12C3([Ir....
227 4HEZ - 1MZ C4 H7 N2 Cn1cc[nH+]....
228 1G52 Kd = 0.29 nM F2B C14 H12 F2 N2 O3 S c1cc(c(c(c....
229 5TY8 Kd = 3.5 uM 7Q1 C9 H7 N O3 c1ccc(cc1)....
230 6YO4 - P8B C5 H8 B10 N O2 S B1234B567B....
231 4Q87 Ki = 14 uM 4FH C6 H4 F3 N O S C1=CN(C(=S....
232 1I9O Kd = 3.8 nM IOC C14 H11 F3 N2 O3 S c1cc(ccc1C....
233 5FLQ Kd = 1080 uM IO2 C15 H14 O3 c1ccc(cc1)....
234 1YDD Kd = 86 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
235 2POV Ki = 75 nM I7B C6 H8 Cl N3 O4 S2 c1c(c(cc(c....
236 1G4J Kd = 2 nM FFB C14 H9 F5 N2 O3 S c1cc(ccc1C....
237 6E91 Ki = 0.08 uM J04 C20 H23 N2 O7 S COc1cc(cc(....
238 3D8W Ki = 7 nM D8W C8 H8 N4 O4 S3 c1ccc(cc1)....
239 5FNH - YIP C8 H6 Cl N4 O c1cc(cc(c1....
240 2WEH Kd = 1125 nM FB1 C6 H6 Cl N O2 S c1ccc(c(c1....
241 5NXP Ki = 10.2 nM 9DH C15 H17 N3 O3 S CN(CC(=O)N....
242 3M67 Kd = 0.18 uM E36 C17 H14 Cl N3 O5 S2 c1cc(c(cc1....
243 1I9M Kd = 3.3 nM INW C14 H12 F2 N2 O3 S c1cc(ccc1C....
244 5JE7 - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
245 2X7S Ki = 1660 nM WZC C19 H27 N O5 S C[C@]12CC[....
246 5BRU - 8TH C30 H35 Cl Ir N3 O4 S2 CCCC12C3([....
247 2FMG - PHE C9 H11 N O2 c1ccc(cc1)....
248 1TTM Kd = 45 nM 667 C14 H15 N O5 S c1cc2c(cc1....
249 5NY6 Ki = 13.5 nM R92 C15 H15 Cl N2 O4 S C[C@@H](c1....
250 3MHM Kd = 0.1 uM J75 C18 H18 N6 O4 S c1ccc(cc1)....
251 2POW Ki = 63 nM I7C C7 H8 F3 N3 O4 S2 c1c(c(cc(c....
252 6RM1 - 45L C8 H10 N2 O Cc1cccc(c1....
253 5TXY Kd = 3.5 uM 7Q1 C9 H7 N O3 c1ccc(cc1)....
254 6YZS Ki = 1296 nM Q3N C7 H12 B10 N O2 S B1234B567B....
255 1AVN Kd = 0.125 mM HSM C5 H9 N3 c1c(nc[nH]....
256 6E8P - HZJ C18 H22 N2 O6 S2 C[C@]12CCc....
257 5EHW Kd = 1005 uM 5OO C9 H6 Cl2 O2 c1cc(c(cc1....
258 1LUG - SUA C13 H14 N2 O3 S3 c1cc(ccc1N....
259 5LJQ Ki = 1 nM ANV C15 H16 N4 O3 S c1ccc(cc1)....
260 4E4A ic50 = 9 mM JKE C7 H6 O2 S c1ccc(c(c1....
261 1ZE8 Ki = 21 nM PIU C16 H21 N2 O2 S Cc1cc([n+]....
262 6UGZ - Q71 C7 H5 F N2 O3 S c1cc2c(cc1....
263 6S9Z - L2K C11 H10 F2 N4 c1cc(c(cc1....
264 1BNN Kd = 0.1 nM AL1 C13 H14 N2 O5 S3 COc1cccc(c....
265 6QL3 Kd = 4.5 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
266 4RUX Ki = 12 nM 3W3 C9 H11 N O3 S C=CCOc1ccc....
267 5BNL - 2HC C9 H8 O3 c1ccc(c(c1....
268 1XQ0 Kd = 454 nM 4TR C16 H13 Br N6 O3 S c1cc(ccc1C....
269 2Q1B Ki = 5950 nM LSA C7 H5 N O3 S c1ccc2c(c1....
270 4Q8Y Ki = 2300 uM HQT C9 H7 N O S c1ccc2c(c1....
271 5THN Ki = 96 uM 7CZ C7 H6 O S C1=CC=C(C(....
272 4YXO Kd = 91.4 nM 4JC C8 H11 N O2 S CCc1ccc(cc....
273 5DOG - 5DT C21 H19 F3 N2 O2 S2 c1ccc(cc1)....
274 3BET ic50 = 1.5 uM CTF C21 H28 N2 O4 S C[C@]12CC[....
275 6QFW Kd = 149 nM JR8 C25 H31 Cl Ir N3 O4 S CC12C3([Ir....
276 6GCY Ki = 50 nM 3QR C16 H18 N4 O9 S c1cc2c(cc1....
277 7JNR Ki = 66.5 nM VFG C5 H8 N4 O3 S2 CCC(=O)Nc1....
278 4R59 Ki = 11 nM 3J3 C11 H22 N2 O10 S2 C1CN(CCC1O....
279 5DRS Kd = 1.1 nM 5EF C17 H17 F3 N2 O5 S2 c1ccc2c(c1....
280 5FDC Ki = 34.8 nM 5WN C9 H10 N2 O2 S2 c1ccc2c(c1....
281 1YDA Kd = 280 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
282 5NXI Ki = 217.4 nM 9DE C12 H11 Br N2 O4 S2 c1cc(ccc1N....
283 1CNX Kd = 43 nM EG2 C13 H21 N3 O5 S c1cc(ccc1C....
284 6RMP - 47S C9 H13 N3 O CN(C)c1ccc....
285 5LMD - RC4 C16 H18 B N2 O5 [B-]1(c2cc....
286 4BCW - TU0 C8 H7 Br O4 S c1cc(c(cc1....
287 5AML Ki = 0.7 nM 51J C11 H12 N2 O6 S2 CC#CCNS(=O....
288 4Q7V Ki = 260 uM 5MH C6 H7 N O S CC1=CN(C(=....
289 3RYX Kd = 7.3 nM RYX C10 H9 F5 N2 O3 S c1cc(ccc1C....
290 5EH5 Kd = 1.35 uM XCZ C5 H7 N3 O2 S Cc1ccnc(n1....
291 1IF9 - SBB C19 H21 N3 O3 S CC[C@H](CN....
292 5FNI Kd = 330 uM YIH C8 H5 Cl2 N4 O c1cc(c(cc1....
293 6RHJ Ki = 2.3 nM K4H C19 H23 N3 O3 S c1ccc(cc1)....
294 4RN4 Ki = 114 nM 3T7 C20 H24 N10 O7 S2 c1ccc(cc1)....
295 2H15 Ki = 2135 nM B19 C12 H22 N2 O7 S CC1(O[C@@H....
296 4Q8Z - 4HO C6 H7 N O2 CC1=CC(=O)....
297 3T82 Ki = 101 nM SG4 C10 H17 N O10 S CC(=O)O[C@....
298 1KWR ic50 = 0.25 uM SG2 C8 H8 N2 O3 S2 CN1c2ccc(c....
299 5THI Ki = 245 uM 0TR C7 H6 O2 C1=CC=C(C(....
300 1OQ5 ic50 = 21 nM CEL C17 H14 F3 N3 O2 S Cc1ccc(cc1....
301 2HL4 Ki = 23 nM BO1 C12 H18 N2 O7 S c1cc(ccc1N....
302 2OSM Ki = 1.05 uM HTS C6 H6 O S c1ccc(c(c1....
303 3P58 Ki = 25.4 nM P58 C9 H11 N S2 CN(Cc1cccc....
304 1G53 Kd = 0.91 nM F6B C14 H12 F2 N2 O3 S c1cc(c(c(c....
305 5WG7 - AUD C4 H5 N O4 S CC1=CC(=O)....
306 4MTY - SBW C14 H14 N2 O4 S c1cc(cc(c1....
307 6T4N Kd = 14 uM F1A C9 H13 N O2 S Cc1cc(c(c(....
308 3BL0 Ki = 121 nM BL0 C5 H10 N4 O2 S2 CN(C)c1nnc....
309 2QOA Ki = 52 nM MAJ C9 H11 N O2 S c1cc2c(cc1....
310 3SAX Kd = 0.14 uM E50 C14 H14 Cl N3 O3 S2 CCc1cnc(nc....
311 4HEY - 4MZ C4 H6 N2 Cc1c[nH]cn....
312 1BCD Kd = 2 nM FMS C H2 F3 N O2 S C(F)(F)(F)....
313 5NEE Ki = 0.02 nM 8V5 C12 H13 N3 O5 S2 c1cc(sc1c2....
314 5E2R Ki = 86.2 nM 520 C19 H16 N2 O3 S c1cc(ccc1c....
315 3RZ7 Kd = 1.1 nM RZ7 C13 H9 F11 N2 O3 S c1cc(ccc1C....
316 3MHL Kd = 0.056 uM J71 C12 H13 N5 O5 S COc1c(c(nc....
317 7K6X - VZ1 C17 H22 N4 O5 S2 Cc1cc(cc(c....
318 2FNN Ki = 200 mM 4MZ C4 H6 N2 Cc1c[nH]cn....
319 3P5L Ki = 40.8 nM IT5 C13 H14 N2 S2 c1ccc(cc1)....
320 5E2S Ki = 0.98 nM 5CX C15 H17 N O2 S CC(C)c1ccc....
321 4Q08 Kd = 500 nM V90 C16 H23 F3 N2 O3 S2 C1CCCC(CCC....
322 2WD3 ic50 = 86 nM MS4 C16 H12 Cl N5 O3 S c1cc(c(cc1....
323 6RVF Ki = 730 nM KKH C14 H14 B N2 O4 B1(c2cc(cc....
324 2POU Ki = 38 nM I7A C6 H6 Cl2 N2 O4 S2 c1c(cc(c(c....
325 6G3Q Ki = 57.9 nM FO9 C8 H17 N7 O2 S3 C1C(=NC(=S....
326 6UGO - Q77 C9 H10 N2 O3 S Cc1cc(c2c(....
327 4E3F ic50 = 3 mM GRE C7 H6 O4 c1cc(c(c(c....
328 3NB5 Ki = 18 nM R21 C16 H17 Cl N2 O4 S c1cc(ccc1C....
329 6EBE Ki = 0.2 uM J3V C14 H11 F3 N4 O6 S c1cc(ccc1C....
330 5AMG Ki = 6 nM IW7 C12 H18 N2 O6 S2 CCCCCNS(=O....
331 2HOC Ki = 0.3 nM 1CN C8 H7 Cl F N5 O4 S3 c1c(cc(c(c....
332 1I9N Kd = 2.2 nM IOA C14 H12 F2 N2 O3 S c1cc(ccc1C....
333 6SAY - L3Q C6 H10 N2 O2 C1CN2[C@@H....
334 6YQU - P92 C7 H5 N O S c1ccc2c(c1....
335 3DD8 Ki = 14 nM 2C7 C16 H21 N O5 S2 c1cc2c(cc1....
336 4Q9Y Ki = 2.1 uM M3T C7 H8 S Cc1cccc(c1....
337 5FLP Kd = 631 uM 6J5 C8 H7 Cl N4 O c1ccc(c(c1....
338 2WEG Kd = 314 nM FBV C6 H6 F N O2 S c1ccc(c(c1....
339 3RZ0 Kd = 28 nM RZ0 C11 H16 N2 O3 S CCCCNC(=O)....
340 4ZWY Ki = 10 nM 4SN C19 H32 N2 O14 S2 CC(=O)OC[C....
341 1CNY Kd = 14 nM EG3 C22 H30 N4 O6 S c1ccc(cc1)....
342 3MMF Ki = 37 nM D9H C11 H13 Cl N6 O3 S c1cc(ccc1N....
343 5TFX Ki = 60.9 nM 7B1 C14 H11 N3 O4 S c1ccc(cc1)....
344 4WW6 Kd = 0.062 nM 3TV C9 H9 F4 N O2 S2 CCCSc1c(c(....
345 3SAP Kd = 0.014 uM E2I C16 H19 N3 O3 S2 CCCCc1cnc(....
346 2FOV Kd = 28 nM B30 C13 H15 Cu N3 O7 S c1cc(ccc1C....
347 2X7U Ki = 5340 nM WZA C19 H27 N O5 S C[C@]12CC[....
348 5JEG - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
349 2NNS Kd = 0.9 uM M25 C10 H14 N2 O3 S CC(=O)NCCc....
350 4Q6E Kd = 0.667 uM KR5 C14 H18 N4 O3 S Cc1cc(n(n1....
351 4JSZ Ki = 5000 uM FB2 C6 H7 N O2 S c1ccc(cc1)....
352 6RH4 - 4NZ C6 H6 N2 O4 S c1cc(ccc1[....
353 5FDI Ki = 18.5 nM 5WM C9 H10 N2 O4 S2 c1ccc2c(c1....
354 6YOL - P5T C5 H8 B9 N O2 S B123B45B16....
355 6WQ9 Ki = 72.5 nM U7J C32 H35 N3 O5 S c1ccc(cc1)....
356 5GMN Kd = 18.8 uM 949 C18 H16 F N O4 S CC1(C(=O)C....
357 3FFP Ki = 72.5 nM LC1 C10 H8 N4 O2 S2 c1cc2c(cc1....
358 3R17 Ki = 390 nM 5UM C12 H11 F N2 O3 S2 c1cc(sc1)C....
359 5SZ2 Ki = 2 nM 72G C13 H11 N O3 S c1cc(cc(c1....
360 2HD6 Ki = 16 nM BOS C13 H12 N2 O3 S2 c1ccc(c(c1....
361 2QO8 Ki = 3.4 nM 3CC C17 H26 N2 O3 S CCCC(CCC)C....
362 5FNJ Kd = 5150 uM YI6 C10 H12 O3 CCOc1ccc(c....
363 1I91 ic50 = 1.15 nM INQ C17 H19 N3 O6 S3 c1cc(cc(c1....
364 4YXI Kd = 318.8 nM 4J8 C7 H9 N O2 S Cc1ccc(cc1....
365 6YZP - Q3H C8 H14 B9 N O2 S B123B45B16....
366 6YZN - Q3Q C6 H10 B10 N O2 S B1234B567B....
367 6YZW Ki = 821.2 nM Q3K C8 H14 B10 N O2 S B1234B567B....
368 6VJ3 - QYA C12 H12 N4 O5 S c1cc(ccc1N....
369 6UFD Ki = 2.9 nM Q6D C15 H14 N2 O4 S2 CC(=O)/C(=....
370 1BN1 Kd = 0.46 nM AL5 C12 H14 N2 O4 S3 Cc1ccc(cc1....
371 5JQT Ki = 8180 nM 6M9 C7 H7 B O2 B1(c2ccccc....
372 1G48 Kd = 3.9 nM F6B C14 H12 F2 N2 O3 S c1cc(c(c(c....
373 5SZ4 - 72D C12 H11 N O2 S c1ccc(cc1)....
374 1AM6 ic50 = 47 uM HAE C2 H5 N O2 CC(=O)NO
375 1OKL Kd = 0.93 uM MNS C12 H14 N2 O2 S CN(C)c1ccc....
376 3OY0 Ki = 10.1 nM OY0 C15 H24 N2 O3 S CCC[C@H](C....
377 2FOS Kd = 27 nM B17 C17 H23 Cu N3 O9 S c1cc(ccc1C....
378 6RRG - FBU C6 H5 F2 N O2 S c1c(cc(cc1....
379 2EZ7 Kd = 43.5 uM DHI C6 H10 N3 O2 c1c([nH+]c....
380 6HX5 Ki = 2.2 uM GXE C6 H6 Se c1ccc(cc1)....
381 3MZC Ki = 226 nM S6I C12 H17 N3 O3 S c1cc(ccc1N....
382 5A6H Ki = 88 nM OE2 C11 H14 Br N3 O5 S c1cc(c(cc1....
383 1IF7 Kd = 30 pM SBR C19 H21 N3 O3 S C[C@H](CNC....
384 7JO1 Ki = 2.1 nM VFJ C6 H10 N4 O3 S2 CCCC(=O)Nc....
385 3DCW Ki < 1 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
386 6T81 Kd = 0.77 uM MUE C10 H9 N O2 S c1ccc2cc(c....
387 5JGS - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
388 3C7P ic50 = 0.1 nM POF C24 H27 N3 O5 S C[C@]12CC[....
389 6MBV - NIO C6 H5 N O2 c1cc(cnc1)....
390 5O07 Ki = 33.8 nM 1VQ C6 H10 N4 O5 S Cc1ncc(n1C....
391 5TH4 - BEW C5 H6 N O S c1cc[n+](c....
392 6RIT - FBV C6 H6 F N O2 S c1ccc(c(c1....
393 6YZK - Q3N C7 H12 B10 N O2 S B1234B567B....
394 3DAZ Ki = 11.8 nM MZM C5 H8 N4 O3 S2 CC(=O)/N=C....
395 4PQ7 Ki = 9.5 nM IL3 C11 H14 N2 O3 S CC#CCOc1cc....
396 6SDS Ki = 37.9 nM L8N C12 H12 N O5 P S c1ccc(cc1)....
397 6RNP - KBB C6 H5 F2 N O2 S c1cc(c(cc1....
398 5L3O - QUJ QUK 6H0 QVS QVE n/a n/a
399 1G54 Kd = 1.5 nM FFB C14 H9 F5 N2 O3 S c1cc(ccc1C....
400 4Z1K Ki = 4.7 nM 4KB C16 H16 N2 O5 S c1cc(ccc1C....
401 4JSS Ki = 500 uM BEW C5 H6 N O S c1cc[n+](c....
402 2Q38 Ki = 5950 nM LSA C7 H5 N O3 S c1ccc2c(c1....
403 3HS4 Ki = 10 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
404 6YO7 - P7Z C8 H16 B10 N2 O4 S2 B1234B567B....
405 4BF6 Ki = 4.5 nM X0Q C13 H9 N5 O2 S2 c1cc(cc(c1....
406 2HKK Ka = 96 M^-1 ALE C9 H13 N O3 CNC[C@@H](....
407 6SB7 - 8K2 C4 H4 Cl N O2 S2 c1cc(sc1S(....
408 7K6U - VYY C16 H20 N4 O5 S2 Cc1ccc(cc1....
409 2NNG Kd = 4.4 uM ZYX C8 H12 N2 O2 S c1cc(ccc1C....
410 3F8E Ki = 59 nM TE1 C15 H20 O5 CC(C)C[C@@....
411 5NYA Ki = 415.6 nM FB2 C6 H7 N O2 S c1ccc(cc1)....
412 5FLO Kd = 709 uM J4K C8 H7 Cl N4 O c1cc(ccc1O....
413 3DD0 Ki < 1 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
414 3ML2 Ki = 9.1 nM SU0 C18 H16 N2 O6 S COc1ccc2c(....
415 6RL9 - SAN C6 H8 N2 O2 S c1cc(ccc1N....
416 4M2R Ki = 3.2 nM BZ1 C12 H21 N3 O5 S3 CCN[C@H]1C....
417 4JSA Ki = 11 uM FB2 C6 H7 N O2 S c1ccc(cc1)....
418 3CYU Kd = 60 nM 0CR C74 H74 N10 O18 S COc1cc2c3c....
419 6EEA Ki = 0.2 uM J3V C14 H11 F3 N4 O6 S c1cc(ccc1C....
420 1IF4 - FBS C6 H6 F N O2 S c1cc(ccc1F....
421 1BNW Kd = 0.83 nM TPD C9 H10 N2 O4 S4 c1cc(sc1)C....
422 2EU3 - FF3 C3 H4 F2 N4 O2 S2 c1(nnc(s1)....
423 2QP6 Ki = 208 nM MB1 C6 H5 Cl N2 O4 S c1cc(c(cc1....
424 6U4Q Ki = 150.3 nM PX7 C8 H8 N2 O3 S CN1c2ccccc....
425 5JES - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
426 5JDV - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
427 4MDM Ki = 6.79 uM 26E C3 H5 B9 N2 O2 S B123B45B16....
428 3RZ8 Kd = 6.7 nM RZ8 C13 H20 N2 O3 S CCCCCCNC(=....
429 3EFT Ki = 12 nM 3BS C16 H25 Cl N4 O3 S2 CC1(CC(CC(....
430 5U0D Kd = 28.6 uM 7R7 C11 H11 N O4 S COc1ccc(c(....
431 6YOK - P82 C8 H16 B10 N2 O4 S2 B1234B567B....
432 1CIN Ki = 1.88 nM MTS C9 H14 N2 O4 S3 C[C@H]1C[C....
433 6ECZ Ki = 0.27 uM J4D C13 H6 F5 N4 O8 S c1c(cc(c(c....
434 6RG4 Ki = 5.4 nM K45 C19 H23 N3 O3 S CN1CCN(C[C....
435 4MLX Ki = 0.65 mM TM7 C6 H6 O2 S CC1=CC(=S)....
436 2FMZ Ki = 35 nM DPN C9 H11 N O2 c1ccc(cc1)....
437 5SZ6 - 72G C13 H11 N O3 S c1cc(cc(c1....
438 3IEO Ki = 331 nM AMJ C13 H18 N2 O3 CC(=O)N[C@....
439 3F4X Ki = 138 nM KLT C14 H11 Cl N2 O4 S c1ccc2c(c1....
440 6YZU Ki = 299.4 nM Q4B C7 H12 B9 N O2 S B123B45B16....
441 3T5U Ki = 5.47 uM A09 C6 H7 N O3 S c1ccc(cc1)....
442 1BNU Kd = 0.2 nM AL3 C11 H12 N2 O5 S4 c1cc(sc1)C....
443 1OKN Kd = 2.3 nM STB C12 H19 N3 O3 S2 c1cc(ccc1C....
444 7JO0 Ki = 12.8 nM VFG C5 H8 N4 O3 S2 CCC(=O)Nc1....
445 3DBU Ki = 8.8 nM D8W C8 H8 N4 O4 S3 c1ccc(cc1)....
446 7K6L Ki = 458.3 nM VZD C15 H17 F N4 O5 S2 c1cc(ccc1N....
447 4MO8 Ki = 10.1 nM 2VQ C6 H11 N5 O4 S Cc1ncc(n1C....
448 1I9P Kd = 3.9 nM IOE C14 H11 F3 N2 O3 S c1cc(ccc1C....
449 6B59 Ki = 8.2 nM CQS C15 H17 N7 O3 S c1cc(ccc1C....
450 3N2P Ki = 15 nM AYX C13 H12 N4 O5 S c1cc(cc(c1....
451 6T4P Kd = 2.9 uM MHK C10 H9 N O2 S c1ccc2c(c1....
452 4QJM Kd = 6.7 nM V1F C21 H19 F3 N2 O4 S2 c1ccc(cc1)....
453 3M40 Kd = 0.17 uM J45 C10 H8 Cl N5 O4 S c1cc(ccc1N....
454 5TY9 Kd = 6.1 uM 7QV C11 H11 N O5 COc1ccc(c(....
455 5NXV Ki = 3.5 nM 9E2 C12 H12 Cl N5 O5 S Cc1c(c(nn1....
456 5NXO Ki = 4.9 nM 9HK C13 H12 N2 O4 S c1cc(ccc1C....
457 2FOU Kd = 80 nM B22 C21 H22 Cu N4 O8 S c1cc(cc(c1....
458 4QSA Kd = 40 nM EWW C13 H12 Cl N3 O4 S2 CC1=CC(=O)....
459 5FNG Kd = 1105 uM YIE C8 H6 Cl N4 c1cc(ccc1C....
460 6QFX Kd = 20 nM JR3 C24 H28 Cl Ir N4 O5 S CC12C3([Ir....
461 4BF1 Ki = 2.4 nM 9FK C16 H12 N4 O2 S2 c1ccc2c(c1....
462 6C7W Ki = 3410 nM LMS C10 H14 N6 O6 S c1nc(c2c(n....
463 4ZWI - 62I C13 H24 N2 O11 S2 CC(=O)OC[C....
464 1BN3 Kd = 0.13 nM AL6 C13 H12 N2 O5 S3 COc1cccc(c....
465 4Q90 Ki = 7 mM 4H2 C6 H7 N S CC1=CC(=S)....
466 5EHV Kd = 826 uM 5ON C18 H16 O5 c1cc(cc(c1....
467 4MDG Ki = 0.7 uM 25X C3 H5 B10 N2 O2 S B1234B567B....
468 6YZR Ki = 333 nM Q3W C6 H10 B9 N O2 S B123B45B16....
469 5JQ0 - 6M4 C7 H8 B O3 [B-]1(c2cc....
470 6RS5 - KGK C7 H5 F4 N O2 S Cc1c(c(c(c....
471 6UX1 ic50 = 6.6 mM SAL C7 H6 O3 c1ccc(c(c1....
472 3MNU Ki = 48 nM BON C12 H19 B N2 O4 S B1(OC(C(O1....
473 2ABE Ki = 113 uM HIS C6 H10 N3 O2 c1c([nH+]c....
474 4HEW - 2MZ C4 H6 N2 Cc1[nH]ccn....
475 5G01 - OE2 C11 H14 Br N3 O5 S c1cc(c(cc1....
476 3RYY Kd = 38 nM RYY C10 H14 N2 O3 S CCCNC(=O)c....
477 5NXW Ki = 57.4 nM RA9 C10 H11 N5 O3 S3 c1cc(ccc1N....
478 6RQI - FBW C6 H6 F N O2 S c1cc(cc(c1....
479 3SBI Kd = 0.017 uM E90 C12 H11 N3 O3 S2 c1cnc(nc1)....
480 6YOI - P7H C8 H16 B10 N2 O4 S2 B1234B567B....
481 5FNL Kd = 826 uM 5ON C18 H16 O5 c1cc(cc(c1....
482 3RZ1 Kd = 1.8 nM RZ1 C12 H9 F9 N2 O3 S c1cc(ccc1C....
483 4QSB Kd = 1300 nM EWY C13 H13 N3 O4 S2 CC1=CC(=O)....
484 1YDB Kd = 5.8 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
485 5EKJ Kd = 1 uM TG4 C14 H23 N3 O3 S CCCCNCC(=O....
486 4Q7W Ki = 2300 uM 6MH C6 H7 N O S CC1=CC=CC(....
487 2EU2 - 5DS C5 H11 N5 O2 S2 CN(C)c1nnc....
488 4CQ0 - SXS C7 H6 N2 O3 S c1cc2c(cc1....
489 1MOO - 4MZ C4 H6 N2 Cc1c[nH]cn....
490 7K6K Ki = 474.5 nM VZ1 C17 H22 N4 O5 S2 Cc1cc(cc(c....
491 3DC3 Ki = 4.9 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
492 3MNA Ki = 41 nM DWH C12 H13 Cl N6 O4 S COC(=O)CNc....
493 6UH0 Ki = 853.1 nM PX7 C8 H8 N2 O3 S CN1c2ccccc....
494 1CNW Kd = 19 nM EG1 C15 H24 N4 O6 S c1cc(ccc1C....
495 7JNZ Ki = 62.8 nM VGV C9 H14 N4 O3 S2 C1CCC(CC1)....
496 6UGP Ki = 685.5 nM Q7A C7 H5 Cl N2 O3 S c1cc2c(c(c....
497 4Z0Q Ki = 6.8 nM 4K9 C16 H16 N2 O3 S c1ccc2c(c1....
498 6ROE - FBT C6 H5 F2 N O2 S c1cc(c(c(c....
499 6YZV Ki = 21 nM Q2Z C4 H6 B10 N O2 S B1234B567B....
500 6YQT - P9E C7 H6 N2 O3 S2 c1cc2c(cc1....
501 4LP6 - Q4I C68 H64 N12 O16 S CC(C)COc1c....
502 5THJ Ki = 1350 uM 0TR C7 H6 O2 C1=CC=C(C(....
503 6YZM - Q4B C7 H12 B9 N O2 S B123B45B16....
504 2HNC Ki = 60 nM 1SA C2 H4 N4 O2 S2 c1(nnc(s1)....
505 6WQ7 Ki = 30.4 nM U6V C28 H35 F N4 O3 S c1ccc(cc1)....
506 6RKN - FBS C6 H6 F N O2 S c1cc(ccc1F....
507 6OE1 Ki = 3.1 nM M8V C16 H20 N4 O5 S c1cc(ccc1N....
508 6RHK Ki = 0.6 nM K4B C17 H19 N3 O3 S c1ccc(cc1)....
509 3S9T Kd = 0.22 uM E49 C14 H14 Cl N3 O3 S2 Cc1cc(nc(n....
510 4ILX Ki = 233 nM 1EZ C18 H24 N2 O3 S c1cc(ccc1N....
511 5AMD Ki = 2.8 nM 45I C15 H16 N2 O6 S2 c1ccc(cc1)....
512 6R6F - EA3 C15 H21 Cl N2 O4 S2 c1c(c(cc(c....
513 3P4V Ki = 8 uM PMX C14 H14 Cl N O6 COC(=O)/C=....
514 7JOC ic50 = 6.4 nM ARZ C13 H18 N4 O3 S2 C1C2CC3CC1....
515 3IBI Ki = 2.6 nM BOW C8 H19 N O3 S CCCCCCCCOS....
516 5JEH - EVF C7 H6 N2 O2 S2 c1ccc2c(c1....
517 2H4N Kd = 0.002 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
518 6EQU Ki = 419 nM BVE C31 H27 N2 O2 S c1ccc(cc1)....
519 5TY1 Kd = 3.5 uM 7QV C11 H11 N O5 COc1ccc(c(....
520 7K6I Ki = 444.5 nM VYV C15 H18 N4 O5 S2 c1ccc(cc1)....
521 6RRI - KFH C6 H3 F4 N O2 S c1c(c(c(c(....
522 5FNM Kd = 791 uM 5O6 C11 H12 O3 C/C(=CC(=O....
523 1ZSB Kd = 250 mM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
524 6E8X Ki = 0.07 uM J0A C19 H22 N2 O7 S2 C[C@]12C=C....
525 3OYQ Ki = 10.3 nM OYQ C13 H20 N2 O3 S CC[C@H](C)....
526 3T85 Ki = 11.3 nM SG7 C10 H17 N O10 S CC(=O)O[C@....
527 1IF5 - FBT C6 H5 F2 N O2 S c1cc(c(c(c....
528 3IBN Ki = 24.5 nM O60 C10 H24 N2 O6 S2 C(CCCCCOS(....
529 4KAP - 1QV C7 H2 F4 N2 O2 S2 c12c(c(c(c....
530 5E28 Ki = 12.3 nM BC5 C12 H12 N2 O2 S c1cc(ccc1c....
531 5WGP - AUD C4 H5 N O4 S CC1=CC(=O)....
532 5LVS - QUJ QUK 6H0 QVS QVE n/a n/a
533 5SZ1 Ki = 1.2 nM 72E C13 H13 N O2 S Cc1ccccc1c....
534 1I90 ic50 = 1.28 nM INM C10 H15 N3 O5 S3 COCCC[N@]1....
535 6D1M Ki = 6.3 nM FQY C12 H17 N O2 S Se c1cc(ccc1S....
536 5NY1 Ki = 366.7 nM 9E5 C19 H20 N2 O4 S Cc1ccc2c(c....
537 4IWZ Ki = 51 nM 1GO C8 H8 N4 O3 S3 c1cc(sc1)C....
538 4E3H Ki = 90 nM HQE C6 H6 O2 c1cc(ccc1O....
539 1I8Z ic50 = 1.27 nM INL C18 H21 N3 O6 S3 COc1cccc(c....
540 6E92 Ki = 0.002 uM HZY C19 H21 N2 O6 S COc1cc(cc(....
541 2F14 Kd = 0.64 nM FL1 C29 H23 N3 O7 S2 c1cc(ccc1C....
542 6UFC Ki = 0.45 nM Q6A C18 H18 N2 O5 S CC(=O)/C(=....
543 3R16 Ki = 50 nM 5UN C12 H12 N2 O3 S2 c1cc(sc1)C....
544 6EEH Ki = 0.29 uM J4D C13 H6 F5 N4 O8 S c1c(cc(c(c....
545 1CIL Ki = 0.372 nM ETS C10 H16 N2 O4 S3 CCN[C@H]1C....
546 5WLV Ki = 3 nM 42G C21 H29 N3 O5 S CC(C)NC[C@....
547 4ZX0 - 5L2 C14 H24 N2 O13 S2 CC(=O)OC[C....
548 6WQ8 Ki = 2.4 nM U77 C26 H31 N3 O6 S c1ccc(cc1)....
549 3MHI Kd = 0.2 uM J90 C11 H11 N5 O5 S c1cc(ccc1C....
550 3DCC Ki = 1.1 nM D9Z C8 H6 Cl N3 O2 S2 c1ccc(c(c1....
551 6UZU Ki = 7 nM 6LU C15 H17 N3 O3 S Cc1cc(cc(c....
552 4KNI Kd = 16.7 nM E1E C14 H14 Cl N3 O3 S2 Cc1cc(nc(n....
553 3IGP Ki = 32.8 nM DT7 C11 H16 N2 O4 S COc1cc2c(c....
554 3RYJ Kd = 16 nM RYJ C9 H9 F3 N2 O3 S c1cc(ccc1C....
555 2FOQ Kd = 235 nM B15 C20 H21 Cu N3 O7 S c1cc(ccc1C....
556 4ZWX Ki = 2 nM 5KZ C19 H32 N2 O14 S2 CC(=O)OC[C....
557 6T4O Kd = 18 uM MJ2 C8 H11 N O2 S Cc1cc(cc(c....
558 5N0D Ki = 3.3 nM 8F2 C22 H20 N2 O5 S c1ccc(cc1)....
559 4Q83 Ki = 64 uM 3FH C6 H4 F3 N O S C1=CN(C(=S....
560 7JO3 Ki = 8.2 nM VGS C7 H12 N4 O3 S2 CC(C)(C)C(....
561 4QJX Kd = 52 nM WWO C15 H15 F3 N2 O5 S2 c1ccc(cc1)....
562 4HU1 Kd = 29 nM V13 C8 H7 F4 N O5 S2 C(CS(=O)(=....
563 6G5U Kd = 6.3 nM ENN C11 H14 Cl2 N2 O3 S CCCCNC(=O)....
564 4KNN Kd = 16.7 nM E1F C12 H10 Cl N3 O3 S2 c1cnc(nc1)....
565 4KNM Kd = 10 nM E1E C14 H14 Cl N3 O3 S2 Cc1cc(nc(n....
566 4QIZ Kd = 7.1 nM WWX C22 H21 F3 N2 O6 S2 c1ccc(cc1)....
567 5E2N Kd = 0.29 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
568 3CZV Ki = 16 nM AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
569 4QJP Kd = 2.5 nM V1F C21 H19 F3 N2 O4 S2 c1ccc(cc1)....
570 4QSJ Kd = 5 nM EWW C13 H12 Cl N3 O4 S2 CC1=CC(=O)....
571 4COQ - SAN C6 H8 N2 O2 S c1cc(ccc1N....
572 4UOV - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
573 5TT3 Ki = 193 nM EZL C9 H10 N2 O3 S2 CCOc1ccc2c....
574 5TUO Ki = 323 nM 1SA C2 H4 N4 O2 S2 c1(nnc(s1)....
575 6Y00 Ki = 653.8 nM O5T C16 H19 Br N4 O4 S c1cc(cc(c1....
576 6EVR Ki = 8.8 nM BZW C20 H23 N3 O4 S CC(=O)N1CC....
577 2NMX Kd = 2.7 uM M25 C10 H14 N2 O3 S CC(=O)NCCc....
578 6HWZ Ki = 6.7 uM GXE C6 H6 Se c1ccc(cc1)....
579 6FAF Ki = 306.1 nM D3B C15 H17 N3 O4 S Cc1ccc(c(c....
580 1BZM - MZM C5 H8 N4 O3 S2 CC(=O)/N=C....
581 2FW4 Kd = 30 nM HIS C6 H10 N3 O2 c1c([nH+]c....
582 6F3B Ki = 273.3 nM CJK C15 H17 N3 O4 S Cc1ccc(cc1....
583 3LXE Ki = 250 nM TOR C12 H21 N O8 S CC1(O[C@@H....
584 6XZS Ki = 724.7 nM O5K C16 H19 F N4 O3 S c1cc(ccc1C....
585 2IT4 Ki = 24.1 mM PPF C H3 O5 P C(=O)(O)P(....
586 2NN7 Kd = 0.3 uM M29 C11 H15 N O4 S CCOC(=O)CC....
587 5E2M Kd = 59 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
588 4WR7 Kd = 0.002 nM 3TV C9 H9 F4 N O2 S2 CCCSc1c(c(....
589 6XZY Ki = 728 nM O5N C16 H19 F N4 O3 S c1ccc(c(c1....
590 6G3V Ki = 922.4 nM FO9 C8 H17 N7 O2 S3 C1C(=NC(=S....
591 6XZO Ki = 138.4 nM O55 C16 H19 Br N4 O4 S c1cc(ccc1N....
592 4WUQ - 3UG C11 H12 F4 N2 O2 S C1CCN(CC1)....
593 6XZX Ki = 928.3 nM O5H C16 H20 N4 O3 S c1ccc(cc1)....
594 6XZE Ki = 24.6 nM O4Z C16 H19 F N4 O3 S c1ccc(c(c1....
595 1CZM - AAS C8 H10 Hg N2 O4 S CC(=O)O[Hg....
596 2NN1 Kd = 1.5 uM M28 C9 H11 N O4 S c1cc(ccc1C....
597 4WUP Kd = 0.15 nM 3UF C8 H11 N O3 S2 c1cc(ccc1S....
598 2FOY Kd = 120 nM B30 C13 H15 Cu N3 O7 S c1cc(ccc1C....
599 5GMM Kd = 29.1 uM 949 C18 H16 F N O4 S CC1(C(=O)C....
600 1AZM - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
601 6EX1 Ki = 49.4 nM N19 C18 H21 N3 O3 S c1ccc(cc1)....
602 4X5S - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
603 4QJ0 Kd = 48 nM WWX C22 H21 F3 N2 O6 S2 c1ccc(cc1)....
604 6T5P Kd = 5.9 uM VD8 C14 H23 N O2 S CC(C)(C)c1....
605 4QJO Kd = 40 nM V1F C21 H19 F3 N2 O4 S2 c1ccc(cc1)....
606 4KP8 Kd = 3330 nM E1G C12 H11 N3 O3 S2 c1cc(cc(c1....
607 4KP5 Kd = 833 nM E1F C12 H10 Cl N3 O3 S2 c1cnc(nc1)....
608 6R71 Kd = 0.12 nM JTW C15 H15 Cl N2 O6 S2 c1ccc(cc1)....
609 6G7A Kd = 0.041 nM EOQ C16 H18 Cl N3 O4 S c1ccc(cc1)....
610 1JD0 - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
611 4QJW Kd = 16 nM WWO C15 H15 F3 N2 O5 S2 c1ccc(cc1)....
612 4HT2 Kd = 290 nM V50 C12 H9 F4 N3 O2 S2 Cc1cc(nc(n....
613 5MSB Kd = 35 nM V13 C8 H7 F4 N O5 S2 C(CS(=O)(=....
614 6R6Y Kd = 0.008 nM EA3 C15 H21 Cl N2 O4 S2 c1c(c(cc(c....
615 4WW8 Kd = 0.067 nM VD9 C9 H13 N O2 S2 CCCSc1ccc(....
616 6G5L Kd = 0.019 nM EM5 C15 H22 Cl N3 O4 S c1c(c(cc(c....
617 4Q0L Kd = 20 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
618 6T5Q Kd = 0.83 uM MKQ C18 H15 N O2 S c1ccc(cc1)....
619 6H36 Ki = 0.45 nM FKE C18 H20 N2 O3 S c1ccc(cc1)....
620 6H37 Ki = 2.6 nM FKQ C18 H20 N2 O4 S c1ccc(cc1)....
621 6H38 Ki = 7.8 nM FKK C18 H20 F N3 O3 S c1cc(ccc1C....
622 3ML5 - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
623 6SDT Ki = 16.1 nM L8N C12 H12 N O5 P S c1ccc(cc1)....
624 6G9U Kd = 0.2 nM ETK C23 H27 F3 N2 O4 S2 c1cc(ccc1C....
625 6G98 Kd = 0.16 nM ER5 C27 H35 F3 N2 O4 S2 c1cc(ccc1C....
626 5FL6 Ki = 43.6 nM Y0R C13 H12 N4 O2 S2 Cc1ccc(cc1....
627 6FE0 Kd = 1.1 nM V90 C16 H23 F3 N2 O3 S2 C1CCCC(CCC....
628 5FL4 Ki = 101 nM 9FK C16 H12 N4 O2 S2 c1ccc2c(c1....
629 3IAI - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
630 6FE1 Kd = 0.05 nM V14 C16 H23 F3 N2 O5 S2 C1CCCC(CCC....
631 5FL5 Ki = 6.4 nM 82E C13 H12 N4 O3 S2 COc1ccc(cc....
632 1FLJ - GSH C10 H17 N3 O6 S C(CC(=O)N[....
633 1DMY - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
634 3F7B ic50 = 64 nM AG5 C20 H19 N3 O3 S2 c1ccc(cc1)....
635 4LU3 - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
636 5CJF Ki = 0.26 nM 520 C19 H16 N2 O3 S c1cc(ccc1c....
637 6IM3 - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
638 4G7A - AZM C4 H6 N4 O3 S2 CC(=O)Nc1n....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: AZM; Similar ligands found: 8
No: Ligand ECFP6 Tc MDL keys Tc
1 AZM 1 1
2 VGS 0.634146 0.935484
3 VFM 0.619048 0.966667
4 VFG 0.619048 0.920635
5 VFJ 0.577778 0.878788
6 VGV 0.490196 0.863636
7 ARZ 0.471698 0.850746
8 1GO 0.446429 0.904762
Similar Ligands (3D)
Ligand no: 1; Ligand: AZM; Similar ligands found: 691
No: Ligand Similarity coefficient
1 S0E 0.9724
2 P9E 0.9723
3 EUE 0.9718
4 4CM 0.9689
5 MZM 0.9669
6 STX 0.9642
7 MAJ 0.9593
8 SKF 0.9562
9 3W8 0.9529
10 ATX 0.9500
11 AM4 0.9487
12 4NZ 0.9483
13 RYV 0.9465
14 AES 0.9448
15 4JE 0.9446
16 6KT 0.9442
17 DA4 0.9434
18 CSN 0.9414
19 SSC 0.9407
20 5GT 0.9390
21 4NP 0.9384
22 U7E 0.9380
23 2O8 0.9358
24 N4E 0.9351
25 2O6 0.9344
26 IOS 0.9344
27 SNO 0.9341
28 0F3 0.9336
29 PNP 0.9332
30 4MB 0.9325
31 QBP 0.9324
32 7O4 0.9322
33 4JC 0.9310
34 UA5 0.9309
35 657 0.9302
36 ZEC 0.9302
37 88L 0.9300
38 3VX 0.9294
39 RNO 0.9287
40 ZYX 0.9285
41 IAC 0.9277
42 DER 0.9271
43 5LD 0.9256
44 5DL 0.9256
45 3VS 0.9255
46 GGB 0.9254
47 RD4 0.9247
48 Z13 0.9245
49 GO2 0.9243
50 K4V 0.9241
51 A7H 0.9231
52 PDC 0.9231
53 HPO 0.9226
54 4I8 0.9225
55 2J3 0.9218
56 OW7 0.9214
57 N91 0.9214
58 A98 0.9214
59 4NS 0.9214
60 JB8 0.9213
61 JDN 0.9212
62 VM1 0.9211
63 M4S 0.9210
64 PRO GLY 0.9208
65 VD9 0.9207
66 4TU 0.9201
67 2FX 0.9199
68 PD2 0.9196
69 7MW 0.9194
70 VC3 0.9194
71 EN1 0.9191
72 FBF 0.9190
73 RKV 0.9189
74 EYV 0.9186
75 LEL 0.9185
76 3W3 0.9181
77 3W6 0.9181
78 0JD 0.9181
79 4NB 0.9180
80 BL0 0.9176
81 EVF 0.9174
82 A7N 0.9173
83 5RP 0.9153
84 IPE 0.9151
85 PUE 0.9147
86 9ZE 0.9147
87 1F1 0.9147
88 TSR 0.9146
89 7UC 0.9145
90 HSA 0.9145
91 6NT 0.9140
92 MB1 0.9140
93 9NB 0.9139
94 8G0 0.9137
95 DX5 0.9137
96 F02 0.9136
97 6NI 0.9131
98 JAW 0.9124
99 GWM 0.9123
100 LQ2 0.9123
101 8NB 0.9122
102 49P 0.9115
103 D1G 0.9111
104 15N 0.9107
105 EWG 0.9102
106 LUQ 0.9100
107 E1T 0.9099
108 CWJ 0.9099
109 G14 0.9098
110 5NI 0.9097
111 5F5 0.9097
112 R5P 0.9090
113 R52 0.9090
114 60L 0.9088
115 SLS 0.9087
116 94W 0.9086
117 3NY 0.9086
118 QIV 0.9084
119 RES 0.9084
120 ZZA 0.9081
121 QMS 0.9078
122 3VQ 0.9076
123 BGT 0.9076
124 TZP 0.9075
125 1L5 0.9074
126 R1P 0.9074
127 DEZ 0.9074
128 492 0.9073
129 0HO 0.9073
130 XCG 0.9072
131 MD6 0.9072
132 3A9 0.9071
133 A5Q 0.9071
134 PTB 0.9070
135 2ZM 0.9070
136 3MB 0.9067
137 OVM 0.9065
138 DVQ 0.9065
139 A5P 0.9061
140 OVP 0.9060
141 5LA 0.9058
142 0HN 0.9058
143 M5H 0.9055
144 N1E 0.9055
145 363 0.9054
146 36M 0.9053
147 EUH 0.9050
148 GCO 0.9050
149 92P 0.9048
150 2HU 0.9047
151 E4P 0.9047
152 6MW 0.9045
153 CIR 0.9044
154 GVA 0.9043
155 LR8 0.9042
156 4TP 0.9040
157 428 0.9040
158 IPR 0.9037
159 ODK 0.9037
160 HJ7 0.9036
161 M78 0.9033
162 N2M 0.9033
163 DZA 0.9032
164 KBZ 0.9030
165 RA7 0.9026
166 6ZX 0.9025
167 M5E 0.9024
168 OW4 0.9023
169 LGT 0.9021
170 TYR 0.9020
171 9R5 0.9020
172 5SP 0.9018
173 KPC 0.9018
174 ABI 0.9017
175 AMH 0.9016
176 HA5 0.9015
177 PFF 0.9014
178 FWB 0.9013
179 S7A 0.9011
180 BQ2 0.9009
181 MNP 0.9009
182 ILO 0.9008
183 ICO 0.9004
184 XI7 0.9004
185 C2Y 0.9004
186 5H6 0.9003
187 KLE 0.9002
188 4BY 0.8999
189 DMA 0.8999
190 DAR 0.8999
191 ARG 0.8999
192 2JJ 0.8996
193 MVH 0.8996
194 AGP 0.8994
195 MS0 0.8994
196 AHN 0.8992
197 5TZ 0.8992
198 BZJ 0.8990
199 7FU 0.8989
200 1FE 0.8988
201 3R4 0.8988
202 6C5 0.8986
203 PML 0.8984
204 PNZ 0.8984
205 Q06 0.8980
206 MKN 0.8978
207 6C9 0.8977
208 MLY 0.8977
209 27B 0.8973
210 XRX 0.8970
211 1X4 0.8969
212 OCA 0.8967
213 C26 0.8967
214 PA5 0.8966
215 1PS 0.8966
216 W81 0.8965
217 3ZB 0.8964
218 Y3L 0.8957
219 SRO 0.8957
220 ANN 0.8956
221 3XR 0.8956
222 JMG 0.8956
223 HG3 0.8956
224 TEG 0.8956
225 D2G 0.8956
226 F4K 0.8956
227 3AE 0.8955
228 2UZ 0.8954
229 5XC 0.8954
230 9FE 0.8951
231 JCZ 0.8951
232 AJ1 0.8950
233 5F8 0.8947
234 LR5 0.8946
235 2BX 0.8946
236 TMG 0.8946
237 2QC 0.8945
238 4BL 0.8945
239 D9Z 0.8943
240 TRP 0.8943
241 4BZ 0.8942
242 C82 0.8940
243 DXP 0.8938
244 NPI 0.8935
245 5OB 0.8935
246 I3E 0.8934
247 RGP 0.8934
248 EE8 0.8933
249 L1T 0.8932
250 M4E 0.8931
251 5RN 0.8931
252 N2I 0.8929
253 XEN 0.8929
254 PEY 0.8928
255 S7J 0.8927
256 9BF 0.8923
257 67X 0.8923
258 EZ1 0.8922
259 HNT 0.8922
260 549 0.8922
261 DNF 0.8920
262 795 0.8919
263 HC4 0.8917
264 NK5 0.8916
265 IOP 0.8916
266 6FG 0.8915
267 6C4 0.8915
268 3VW 0.8915
269 AVA 0.8914
270 KYA 0.8912
271 8V8 0.8910
272 EV2 0.8910
273 GJP 0.8908
274 TYL 0.8908
275 KDG 0.8907
276 5TO 0.8906
277 P93 0.8906
278 FCD 0.8904
279 5XB 0.8904
280 SEP 0.8903
281 DED 0.8903
282 DRG 0.8903
283 1HN 0.8903
284 5GV 0.8897
285 BSA 0.8896
286 BVA 0.8896
287 D3G 0.8895
288 4RU 0.8895
289 5DS 0.8892
290 A6W 0.8890
291 5O6 0.8889
292 M1T 0.8889
293 YIE 0.8889
294 ZYQ 0.8888
295 NPX 0.8888
296 JBZ 0.8887
297 UN1 0.8886
298 AKG 0.8886
299 LX1 0.8882
300 0NX 0.8882
301 ZHA 0.8881
302 8D6 0.8879
303 GZ2 0.8878
304 M2K 0.8878
305 3PG 0.8878
306 OGA 0.8877
307 DHY 0.8876
308 5WZ 0.8876
309 78Y 0.8873
310 L14 0.8872
311 LZ5 0.8870
312 GK8 0.8869
313 6C8 0.8868
314 DEW 0.8866
315 DAH 0.8863
316 HLP 0.8863
317 E5X 0.8863
318 P81 0.8862
319 TSU 0.8861
320 6HO 0.8860
321 YE6 0.8859
322 0LO 0.8859
323 I2E 0.8857
324 9UL 0.8857
325 8ZE 0.8856
326 27K 0.8856
327 TSS 0.8852
328 5OY 0.8852
329 SG2 0.8852
330 9FH 0.8850
331 KNA 0.8850
332 AAN 0.8849
333 BZ2 0.8847
334 8XL 0.8847
335 KDV 0.8846
336 QME 0.8846
337 YZM 0.8846
338 SG3 0.8844
339 12T 0.8844
340 X0U 0.8843
341 5FL 0.8843
342 SNU 0.8842
343 36E 0.8841
344 BZQ 0.8839
345 PSJ 0.8839
346 IQ5 0.8839
347 ENW 0.8838
348 PQZ 0.8838
349 4JK 0.8838
350 WT2 0.8838
351 80G 0.8834
352 30G 0.8834
353 F9Y 0.8833
354 BOQ 0.8833
355 J6W 0.8833
356 EXY 0.8832
357 J38 0.8831
358 EXD 0.8830
359 OA1 0.8830
360 ALE 0.8829
361 NPA 0.8829
362 MQB 0.8826
363 M4N 0.8826
364 UNJ 0.8826
365 PPY 0.8825
366 KMY 0.8823
367 PPT 0.8822
368 2D2 0.8821
369 CFA 0.8821
370 CPZ 0.8821
371 OQC 0.8819
372 BIK 0.8819
373 0L1 0.8818
374 64Z 0.8818
375 RYY 0.8817
376 3R6 0.8817
377 F4E 0.8817
378 IBP 0.8817
379 OOG 0.8817
380 BZ3 0.8815
381 9FL 0.8815
382 4FE 0.8814
383 HLD 0.8814
384 9CA 0.8814
385 6FB 0.8812
386 NLA 0.8811
387 H4E 0.8811
388 EQW 0.8811
389 0FK 0.8811
390 ESX 0.8809
391 CXH 0.8808
392 MSL 0.8808
393 TCA 0.8808
394 MS9 0.8807
395 YI6 0.8807
396 8CC 0.8806
397 NVU 0.8805
398 FTV 0.8804
399 1VK 0.8803
400 8U3 0.8803
401 NAG 0.8803
402 HAR 0.8802
403 NPS 0.8802
404 2HC 0.8801
405 KLS 0.8801
406 4FF 0.8801
407 MSR 0.8801
408 YPN 0.8800
409 PH3 0.8800
410 K82 0.8799
411 M6Z 0.8796
412 CS2 0.8796
413 0K7 0.8796
414 1IT 0.8794
415 ABF 0.8794
416 4TB 0.8793
417 8HC 0.8793
418 DG2 0.8792
419 Y4L 0.8790
420 CKA 0.8789
421 2K8 0.8788
422 LVD 0.8788
423 5TY 0.8788
424 Q02 0.8787
425 6SD 0.8786
426 463 0.8786
427 TCR 0.8786
428 5E5 0.8786
429 5NS 0.8782
430 LZ2 0.8782
431 0OL 0.8782
432 MR1 0.8782
433 GLO 0.8778
434 AMR 0.8777
435 S3P 0.8777
436 TFM 0.8776
437 0F9 0.8775
438 PLP 0.8775
439 AVO 0.8775
440 ONR 0.8774
441 V1T 0.8774
442 BPN 0.8772
443 WV7 0.8771
444 EZL 0.8770
445 LRW 0.8770
446 NF3</