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Receptor
PDB id Resolution Class Description Source Keywords
3HYW 2 Å EC: 1.8.5.- 3-D X-RAY STRUCTURE OF THE SULFIDE:QUINONE OXIDOREDUCTASE OF THE HYPERTHERMOPHILIC BACTERIUM AQUIFEX AEOLICUS IN COMPLEXW ITH DECYLUBIQUINONE AQUIFEX AEOLICUS MONOTOPIC MEMBRANE PROTEIN FLAVOPROTEIN POLYSULFUR OXIDOREDUCTASE
Ref.: THE STRUCTURE OF AQUIFEX AEOLICUS SULFIDE:QUINONE OXIDOREDUCTASE, A BASIS TO UNDERSTAND SULFIDE DETOXIFICATION AND RESPIRATION PROC.NATL.ACAD.SCI.USA V. 106 9625 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DCQ A:500;
B:500;
C:500;
D:500;
E:500;
F:500;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
322.439 C19 H30 O4 CCCCC...
FAD H2S A:441;
B:441;
C:441;
D:441;
E:441;
F:441;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data n/a n/a n/a n/a
LMT A:600;
B:600;
C:600;
D:600;
E:600;
F:600;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
510.615 C24 H46 O11 CCCCC...
PS9 A:800;
B:800;
B:802;
C:800;
D:800;
D:802;
E:800;
F:800;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
256.52 S8 S1SSS...
SO4 A:431;
A:432;
A:433;
A:434;
A:435;
B:431;
B:432;
B:433;
B:434;
C:431;
C:432;
C:433;
C:434;
D:431;
D:432;
D:433;
D:434;
E:432;
E:433;
E:434;
F:431;
F:432;
F:433;
F:434;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3HYW 2 Å EC: 1.8.5.- 3-D X-RAY STRUCTURE OF THE SULFIDE:QUINONE OXIDOREDUCTASE OF THE HYPERTHERMOPHILIC BACTERIUM AQUIFEX AEOLICUS IN COMPLEXW ITH DECYLUBIQUINONE AQUIFEX AEOLICUS MONOTOPIC MEMBRANE PROTEIN FLAVOPROTEIN POLYSULFUR OXIDOREDUCTASE
Ref.: THE STRUCTURE OF AQUIFEX AEOLICUS SULFIDE:QUINONE OXIDOREDUCTASE, A BASIS TO UNDERSTAND SULFIDE DETOXIFICATION AND RESPIRATION PROC.NATL.ACAD.SCI.USA V. 106 9625 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3HYW - DCQ C19 H30 O4 CCCCCCCCCC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3HYW - DCQ C19 H30 O4 CCCCCCCCCC....
50% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 3T2Z - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 3T2Y - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 3SXI - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 3SZW - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 3KPK - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 3SY4 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 3T14 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
8 3SYI - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
9 3SZF - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
10 3T2K - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
11 3T0K - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
12 3SZC - DCQ C19 H30 O4 CCCCCCCCCC....
13 3T31 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
14 3SX6 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
15 3SZ0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
16 3HYW - DCQ C19 H30 O4 CCCCCCCCCC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DCQ; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 DCQ 1 1
2 UQ1 0.4 0.742857
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 213
This union binding pocket(no: 1) in the query (biounit: 3hyw.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 2NNQ T4B None
2 5J75 6GQ 1.13636
3 1LOX RS7 1.16279
4 1OPK P16 1.16279
5 1YMT DR9 1.21951
6 1YP0 PEF 1.25523
7 5EYT AMP 1.39535
8 2P8U COA 1.62791
9 1ZDT PEF 1.65975
10 2YJD YJD 1.66667
11 2WH8 II2 1.69492
12 4K26 SFF 1.81159
13 1M13 HYF 1.89873
14 3WYJ H78 1.97628
15 6BR8 PGV 1.98413
16 6BR8 6OU 1.98413
17 3RGA ILD 2.12014
18 5EEH P9P 2.12766
19 5EEH SAH 2.12766
20 4V24 GYR 2.15633
21 5LPA 71R 2.22222
22 5LPA ATP 2.22222
23 4TX6 38B 2.25806
24 3O01 DXC 2.27273
25 5KOR GDP 2.30326
26 3DZT EAH 2.31023
27 3D9F N6C 2.32558
28 3D9F FAD 2.32558
29 3COW 52H 2.32558
30 4Q6R 30J 2.32558
31 2EVL GAL SPH EIC 2.39234
32 3ABI NAD 2.46575
33 5C2H 4PX 2.48619
34 2R0N TGC 2.53807
35 4NKW PLO 2.55814
36 3F5K CE5 2.55814
37 3FWN 6PG 2.55814
38 3VVY ET 2.57732
39 5MOB A8S 2.58621
40 2A1L PCW 2.59259
41 4R6W SAH 2.71318
42 3PG7 PTY 2.73438
43 1UDY FAD 2.77778
44 1UDY CS8 2.77778
45 2E9L BGC 2.7907
46 2E9L PLM 2.7907
47 5LNQ CAA 2.7907
48 6AOV SIA GAL NAG GAL NAG 2.87356
49 5KBZ 3B2 2.91777
50 4WGF HX2 2.92683
51 6AP6 TLF 2.97398
52 3MPI GRA 3.02267
53 2WYA HMG 3.02326
54 1EWF PC1 3.02326
55 5MBC FMN 3.11615
56 6ALW BNV 3.125
57 6ALW BMJ 3.125
58 4KVX ACO 3.20513
59 3VC1 GST 3.20513
60 2H7C COA 3.25581
61 4ZBR DIF 3.25581
62 4ZBR NPS 3.25581
63 1XPM CAA 3.28283
64 3WCA FPS 3.28767
65 3FAL REA 3.30579
66 4IQY AR6 3.33333
67 1FCZ 156 3.40426
68 1DKF OLA 3.43348
69 4POJ 2VP 3.4632
70 4M8E 29V 3.4632
71 1YKI NFZ 3.48837
72 1YKI FMN 3.48837
73 3AHO 3A2 3.48837
74 3H0A 9RA 3.50877
75 3H0A D30 3.50877
76 1YOK P6L 3.51562
77 1YUC EPH 3.52941
78 3PVT 3HC 3.53698
79 4YRY FAD 3.62319
80 1ZDU P3A 3.67347
81 4XQC 13D 3.72093
82 3HR1 PF9 3.72093
83 1POC GEL 3.73134
84 3F8K COA 3.75
85 4A2B AGS 3.81862
86 4A2A ATP 3.81862
87 6MPT C30 3.84615
88 3JRS A8S 3.84615
89 6F7L CWH 3.84615
90 5UR6 8KM 3.8674
91 5LX9 OLB 3.87324
92 1P1M MET 3.94089
93 4KVL PLM 3.95349
94 5KKB BMA NAG MAN MAN MAN MAN MAN MAN MAN 3.95349
95 2XXP DSL 4.0201
96 3FPF TNA 4.02685
97 3FPF MTA 4.02685
98 2OO8 RAJ 4.10095
99 5CYV WCA 4.10959
100 6D6L FY4 4.11765
101 4KIB SAH 4.20168
102 4ELG 52J 4.21687
103 6ADI 9UO 4.29594
104 3MBG FAD 4.31655
105 5IXH OTP 4.34783
106 4Y9J UCC 4.4186
107 4KWD JF2 4.4586
108 5LD8 6U5 4.5977
109 5IGI ZIT 4.65116
110 5IGI GMP 4.65116
111 3RLB VIB 4.6875
112 3KDU NKS 4.69314
113 3SSO SAH 4.77327
114 1T27 PCW 4.79705
115 3O55 FAD 4.8
116 1OQC FAD 4.8
117 2NPA MMB 4.81482
118 6AP8 BNY 4.83271
119 4E5N NAD 4.84848
120 6EOP F15 4.88372
121 3VP6 HLD 4.88372
122 2DVX 23A 4.89297
123 4DYG MES 4.91803
124 5W7B MYR 4.96454
125 3VZS NAP 5.05837
126 4JD3 COA 5.09915
127 4JD3 PLM 5.09915
128 5ECP ATP 5.11628
129 5V2J UDP 5.11628
130 5V2J 7WV 5.11628
131 6CBO DOW 5.11628
132 3A4X NAG NAG NAG NDG 5.14469
133 1NU4 MLA 5.15464
134 3NJQ NJQ 5.18135
135 1P3D ANP 5.34884
136 3FYS PLM 5.39683
137 3SXN COA 5.45024
138 5AAV GW5 5.55556
139 2BJ4 OHT 5.55556
140 4KBS PX2 5.5814
141 1GQY ACP 5.5814
142 3RYC GTP 5.59441
143 2HJ3 FAD 5.6
144 4MUV PCG 5.6338
145 6BR9 PGV 5.81395
146 2E3N 6CM 5.88235
147 2F99 AKV 5.88235
148 3LDW ZOL 6.06061
149 6H21 UD1 6.08696
150 2ART LPA AMP 6.10687
151 4XPL ACO 6.13497
152 2WCJ M21 6.38298
153 4LNU GTP 6.46154
154 4LY9 1YY 6.51163
155 4LY9 S6P 6.51163
156 1G63 FMN 6.62983
157 4D7M TDC 6.91244
158 3E7O 35F 6.94444
159 3FS1 MYR 6.95652
160 5ICK FEZ 6.9869
161 3QUZ QUV 7.07071
162 3RUG DB6 7.07071
163 3L9R L9Q 7.14286
164 3OJI PYV 7.40741
165 2AX9 BHM 7.42188
166 4E2J MOF 7.6
167 4XU6 TDA 7.61905
168 1SR7 MOF 7.72201
169 2O3Z AI7 7.74908
170 4OAR 2S0 7.75194
171 3V49 PK0 7.89474
172 1XVB BHL 8.13953
173 1LRI CLR 8.16327
174 3BM1 FMN 8.19672
175 3WH1 NAG NAG NAG NAG 8.25243
176 1TXR BES 8.69565
177 4WO4 JLS 9
178 1LVK MNT BEF 9.06977
179 3HUJ AGH 9.09091
180 1KZN CBN 9.26829
181 4U31 MVP 9.53488
182 2ZXG S23 9.76744
183 5N7O 69Y 9.95475
184 1NHZ 486 10.3571
185 1M2Z BOG 10.5058
186 1EZV SMA 10.8108
187 5UGW GSH 10.8571
188 5UAV TFB 10.8696
189 5UAV NDP 10.8696
190 3CX5 SMA 12.037
191 2JAP J01 12.1457
192 3GWL FAD 13.2075
193 1VPV PLM 13.3333
194 3ZLM ANP 14.3617
195 2A06 SMA 14.5161
196 5U6V 7WY 15.4545
197 1FM9 9CR 16
198 5NNT DPV 16.2162
199 3KO0 TFP 16.8317
200 4NB5 2JT 16.9591
201 5M36 9SZ 18.4211
202 2HFP NSI 19.0476
203 2DYS PEK 20.4082
204 2DYR PEK 20.4082
205 5Z84 CHD 20.4082
206 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 20.4082
207 4J7Q B7N 21.021
208 1RDT L79 21.7391
209 4MGB XDH 23.0769
210 6A5Y 9CR 25
211 1RV1 IMZ 25.8824
212 5EIB GTP 26.087
213 1PZL MYR 28.5714
Pocket No.: 2; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 37
This union binding pocket(no: 2) in the query (biounit: 3hyw.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 3HB5 NAP 1.52905
2 4QJR PIZ 1.63265
3 3LN0 52B 2.09302
4 2NVA PL2 2.15054
5 1R6T TYM 2.32558
6 2OBD PCW 2.7907
7 3LCC SAH 2.97872
8 2LBD REA 2.99625
9 3OZV FAD 3.22581
10 3OZV ECN 3.22581
11 4LA7 A1O 3.62538
12 3JUQ AKD 4.32432
13 3JUQ AJD 4.32432
14 5ECP MET 5.11628
15 5ECP JAA 5.11628
16 1IUP ALQ 5.31915
17 3HLX PQQ 5.42636
18 2B4Q NAP 5.43478
19 3FRQ ERY 5.64103
20 1WWZ ACO 5.66038
21 3Q9N COA 5.67376
22 5W7R 9Z7 5.82751
23 2FDW D3G 6.27907
24 4G31 0WH 6.35452
25 3VNM SDD 6.48464
26 2R40 EPH 6.76692
27 3KMZ EQO 6.76692
28 4OIV XX9 7.07965
29 4F7E 0SH 7.14286
30 3KFC 61X 7.50988
31 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 8.08081
32 5UXH GFB 8.17439
33 5EPO TUD 8.39695
34 5EOO CIT 8.67924
35 1N1G BCP 9.01639
36 2DYS TGL 20.4082
37 5ZCO CHD 20.4082
Pocket No.: 3; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 21
This union binding pocket(no: 3) in the query (biounit: 3hyw.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 3RDE OYP 1.16279
2 5FI3 NAP 1.40056
3 2I0G I0G 1.55642
4 1XPK CAA 1.80412
5 1K97 CIR 2.09302
6 1K97 ASP 2.09302
7 5U3B 7TD 3.67893
8 3WXL ADP 3.72093
9 3STD MQ0 4.84848
10 2YB9 HA0 4.88372
11 6C8R EQV 5.01319
12 4GBD MCF 5.11628
13 5A8E XTK 5.71429
14 5LGA 6VH 6.66667
15 3OKI OKI 6.86695
16 2VZZ SCA 6.88073
17 3L9R L9R 7.14286
18 2AIB ERG 7.14286
19 2HFN FMN 7.18954
20 5CHR 4NC 13.8686
21 3SE5 ANP 27.439
Pocket No.: 4; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 23
This union binding pocket(no: 4) in the query (biounit: 3hyw.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 5G57 6M5 1.66667
2 1KOR SIN 2
3 1KOR ARG 2
4 1KOR ANP 2
5 1BUC CAA 2.08877
6 3T58 FAD 2.09302
7 1YKD CMP 2.26131
8 1JXZ BCA 2.97398
9 5MZI FAD 3.48837
10 5MZI FYK 3.48837
11 3O3O 2RH 4.15584
12 4CSV STI 4.36364
13 2WET FAD 4.65116
14 2QE4 JJ3 5.64516
15 6GWR FEW 5.71429
16 4QYS PLP SEP 6.04651
17 2GTE VA 6.45161
18 3G08 FEE 7.07071
19 4IGH FMN 10.2151
20 4IGH ORO 10.2151
21 4IGH 1EA 10.2151
22 2Y31 SMQ 13.1086
23 5W97 CHD 20.4082
Pocket No.: 5; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 48
This union binding pocket(no: 5) in the query (biounit: 3hyw.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 4RJD TFP None
2 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 2.04082
3 4M0R 644 2.37467
4 1PZG A3D 2.41692
5 2V58 LZJ 2.44989
6 5TCI 79V 2.53623
7 6CS8 F9Y 2.64026
8 4WX0 HXD 2.6616
9 3N17 NAG NAG 2.7027
10 2OBD 2OB 2.7907
11 5X1M THG 2.7907
12 5X1M DHB 2.7907
13 4GFD 0YB 3.41463
14 1X0P FAD 3.4965
15 3B1Q NOS 3.68098
16 3C9U ADP 3.80117
17 4PLG NAI 3.89222
18 4PLG OXM 3.89222
19 5TIV A3P 3.95257
20 4Z87 5GP 3.95349
21 4DXD 9PC 4.0404
22 2YG2 FLC 4.06977
23 2YG2 S1P 4.06977
24 1PVN MZP 4.25532
25 4KCF AKM 4.65116
26 2WPX ACO 4.71976
27 2WPW ACO 4.71976
28 5B4B LP5 4.83871
29 3FEI CTM 4.86891
30 4Z0G 5GP 5.08475
31 4RVU NDP 5.12048
32 4B7X NAP 5.35714
33 4UA3 COA 5.6701
34 2C6Q NDP 5.98291
35 1GHE ACO 6.21469
36 5CSD ACD 6.91824
37 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 7
38 1Y60 H4M 7.10059
39 4BVA T3 7.16418
40 3ANP DAO 7.35294
41 3JYN NDP 7.69231
42 3IQE F42 7.77385
43 4CRZ ACO 10.9489
44 6GH1 ARG LEU PRO ALA LYS ALA PRO LEU LEU 13.8686
45 2D5A COA 13.8889
46 5U98 1KX 14.0794
47 4HEE 14R 16
48 3T03 3T0 22.2222
Pocket No.: 6; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 25
This union binding pocket(no: 6) in the query (biounit: 3hyw.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 5OHJ 9VE 0.950119
3 4XOQ F42 1.44928
4 2YVK MRU 2.40642
5 3GFZ FMN 2.42131
6 5UC9 MYR 2.65487
7 2Q4V ACO 2.94118
8 1JF0 CZH 3.58974
9 3A51 VDY 3.64964
10 1ZVX FIN 3.68098
11 1GEG GLC 3.72093
12 4WEY EG6 4.7619
13 2ZFZ ARG 5.06329
14 1RQJ RIS 5.68562
15 1LLO NAA NAA AMI 5.86081
16 3D78 NBB 5.88235
17 3R9C ECL 5.98086
18 3A4V PYR 6.30915
19 2XFH CL6 6.56934
20 1HG4 LPP 6.81004
21 2CKM AA7 9.30233
22 5L7G 6QE 10.4918
23 4P6W MOF 10.7143
24 2Y69 CHD 15.5039
25 1K7L 544 19.0476
Pocket No.: 7; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 13
This union binding pocket(no: 7) in the query (biounit: 3hyw.bio3) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 3Q8G PEE 1.25
2 3HB5 E2B 1.52905
3 5XVG 8FX 1.70648
4 5X93 K87 2.15517
5 4BJZ P3A 2.35849
6 4BJZ FAD 2.35849
7 2E2R 2OH 3.27869
8 1N46 PFA 4.65116
9 6B3A SAM 4.65116
10 5KAU RHQ 7.87879
11 3TDC 0EU 8.83721
12 5ODQ FAD 9.0301
13 4WQ2 3SU 12.7168
Pocket No.: 8; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 4
This union binding pocket(no: 8) in the query (biounit: 3hyw.bio3) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 2HUI GLV 1.27226
2 3MDV CL6 3.48837
3 4QOM PYG 5.34884
4 3ANP DCC 7.35294
Pocket No.: 9; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 12
This union binding pocket(no: 9) in the query (biounit: 3hyw.bio3) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 3AGC RCC 1.44928
2 2P1C GG3 1.79487
3 1XW6 GSH 2.75229
4 2E9L OLA 2.7907
5 2GJ5 VD3 3.08642
6 6F7L FAD 3.84615
7 5ICE SAH 4.88372
8 5HWO HMG 6.90476
9 1MT1 AG2 7.07965
10 1MGP PLM 10.2236
11 4ORR PE3 11.0526
12 5HCV 60R 12.4514
Pocket No.: 10; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 6
This union binding pocket(no: 10) in the query (biounit: 3hyw.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 2V2V V12 1.47601
2 3NUG NAD 2.42915
3 5TBM 79A 5.21739
4 1TMX HGX 5.80205
5 1FM9 570 16
6 1RDT 570 21.7391
Pocket No.: 11; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 4
This union binding pocket(no: 11) in the query (biounit: 3hyw.bio3) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 5K7K 6RJ 3.02326
2 3JZB 4HY 4.49438
3 4NJH SAM 13.4783
4 4NJH 2K8 13.4783
Pocket No.: 12; Query (leader) PDB : 3HYW; Ligand: DCQ; Similar sites found with APoc: 4
This union binding pocket(no: 12) in the query (biounit: 3hyw.bio3) has 14 residues
No: Leader PDB Ligand Sequence Similarity
1 1W0O DAN 1.39535
2 1TO9 HMH 1.92308
3 5C1M OLC 5.74324
4 5H5A 6OU 10
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