Receptor
PDB id Resolution Class Description Source Keywords
3EYA 2.5 Å EC: 1.2.2.2 STRUCTURAL BASIS FOR MEMBRANE BINDING AND CATALYTIC ACTIVATION OF THE PERIPHERAL MEMBRANE ENZYME PYRUVATE O XIDASE FROM ESCHERICHIA COLI ESCHERICHIA COLI PYRUVATE OXIDASE MEMBRANE-ASSOCIATED FLAVOPROTEIN DEHYDROGENASE INTERACTIONS WITH LIPIDS CELL MEMBRANE FADFLAVOPROTEIN LIPID-BINDING MAGNESIUM MEMBRANE OXIDOREDUCTASE THIAMINE PYROPHOSPHATE
Ref.: STRUCTURAL BASIS FOR MEMBRANE BINDING AND CATALYTIC ACTIVATION OF THE PERIPHERAL MEMBRANE ENZYME PYRUVATE OXIDASE FROM ESCHERICHIA COLI. PROC.NATL.ACAD.SCI.USA V. 105 17390 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:612;
B:612;
C:612;
D:612;
E:612;
F:612;
G:612;
H:612;
I:612;
J:612;
K:612;
L:612;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
MG A:613;
B:613;
C:613;
D:613;
E:613;
F:613;
G:613;
H:613;
I:613;
J:613;
K:613;
L:613;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
PO4 A:614;
A:615;
A:616;
A:617;
A:618;
A:619;
B:614;
B:615;
B:616;
C:614;
C:615;
D:614;
D:615;
D:616;
D:617;
D:618;
D:619;
D:620;
E:614;
E:615;
F:614;
F:615;
G:614;
G:615;
G:616;
H:614;
H:615;
I:614;
I:615;
J:614;
K:614;
L:614;
L:615;
L:616;
L:617;
L:618;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
TDP A:611;
B:611;
C:611;
D:611;
E:611;
F:611;
G:611;
H:611;
I:611;
J:611;
K:611;
L:611;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
424.306 C12 H18 N4 O7 P2 S Cc1c(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3EYA 2.5 Å EC: 1.2.2.2 STRUCTURAL BASIS FOR MEMBRANE BINDING AND CATALYTIC ACTIVATION OF THE PERIPHERAL MEMBRANE ENZYME PYRUVATE O XIDASE FROM ESCHERICHIA COLI ESCHERICHIA COLI PYRUVATE OXIDASE MEMBRANE-ASSOCIATED FLAVOPROTEIN DEHYDROGENASE INTERACTIONS WITH LIPIDS CELL MEMBRANE FADFLAVOPROTEIN LIPID-BINDING MAGNESIUM MEMBRANE OXIDOREDUCTASE THIAMINE PYROPHOSPHATE
Ref.: STRUCTURAL BASIS FOR MEMBRANE BINDING AND CATALYTIC ACTIVATION OF THE PERIPHERAL MEMBRANE ENZYME PYRUVATE OXIDASE FROM ESCHERICHIA COLI. PROC.NATL.ACAD.SCI.USA V. 105 17390 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3EYA - TDP C12 H18 N4 O7 P2 S Cc1c(sc[n+....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3EYA - TDP C12 H18 N4 O7 P2 S Cc1c(sc[n+....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3EYA - TDP C12 H18 N4 O7 P2 S Cc1c(sc[n+....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Ligand no: 2; Ligand: TDP; Similar ligands found: 32
No: Ligand ECFP6 Tc MDL keys Tc
1 TDP 1 1
2 TPP 0.84 0.985714
3 V4E 0.797468 0.985714
4 TPS 0.77027 0.942857
5 TMV 0.75 0.944444
6 VNP 0.703704 0.945205
7 N1T 0.674699 1
8 2TP 0.609195 0.918919
9 VIB 0.605263 0.760563
10 5SR 0.582418 0.958333
11 FTP 0.574713 0.847222
12 O2T 0.546392 0.896104
13 PYI 0.483871 0.873239
14 TDW 0.474227 0.958333
15 HTL 0.474227 0.945205
16 THV 0.46 0.945205
17 TD6 0.457143 0.907895
18 WWF 0.455446 0.92
19 TOG 0.451923 0.907895
20 TPW 0.451613 0.885714
21 THY 0.45098 0.932432
22 TD9 0.448598 0.907895
23 TD8 0.448598 0.907895
24 THW 0.447619 0.945205
25 TDL 0.446602 0.884615
26 TDK 0.442308 0.907895
27 D7K 0.415929 0.896104
28 TPU 0.410526 0.828947
29 R1T 0.405941 0.873239
30 S1T 0.405941 0.873239
31 T6F 0.403509 0.884615
32 T5X 0.403509 0.884615
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: 90
This union binding pocket(no: 1) in the query (biounit: 3eya.bio3) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4B2D SER 0.009433 0.43904 1.45985
2 1WUU ANP 0.01331 0.40015 1.75439
3 4AZT SAM 0.002845 0.4398 1.82149
4 5X62 SAH 0.005854 0.42887 1.97044
5 3PT9 SAH 0.0169 0.40405 2.00364
6 1XDS SAM 0.009863 0.42533 2.13904
7 1QZZ SAM 0.01407 0.41772 2.13904
8 1YXM ADE 0.02562 0.41207 2.31023
9 4KRG SAH 0.006036 0.42824 2.36052
10 4YDD MD1 0.007288 0.40908 2.4024
11 4YDD MGD 0.007288 0.40908 2.4024
12 1V59 NAD 0.007484 0.43523 2.51046
13 1X87 NAD 0.002083 0.43194 2.55009
14 5F8F SFG 0.001675 0.45867 2.65252
15 4I5I NAD 0.0002101 0.41822 2.78746
16 5HJM MTA 0.005806 0.42215 2.84091
17 2UYQ SAM 0.002847 0.47807 2.90323
18 2EG5 SAH 0.005647 0.43724 2.95699
19 1F3L SAH 0.01216 0.40186 3.11526
20 2CDO GAL AAL GAL AAL GAL AAL 0.0302 0.4006 3.125
21 4KRI SAH 0.009912 0.40862 3.23326
22 3RIY NAD 0.0002102 0.42201 3.2967
23 2NYR SVR 0.005819 0.41739 3.32103
24 3O7W SAM 0.0098 0.42546 3.40136
25 1KYZ SAH 0.003543 0.43913 3.56164
26 3DXY SAM 0.01408 0.4214 3.66972
27 5MGZ SAH 0.01487 0.40364 3.81356
28 2J5V PCA 0.04442 0.42594 3.81471
29 1DJL NAP 0.0003035 0.42617 3.86473
30 3GU3 SAH 0.001257 0.47927 3.87324
31 4OBW SAM 0.003099 0.43809 3.89105
32 1QGQ UDP 0.02942 0.41252 3.92157
33 2XVM SAH 0.01647 0.41435 4.0201
34 1O97 FAD 0.000023 0.40604 4.0625
35 1O97 AMP 0.000023 0.40604 4.0625
36 2CUN 3PG 0.03425 0.40154 4.14634
37 2Z4T C5P 0.04295 0.40017 4.28016
38 1D4O NAP 0.0002206 0.4108 4.34783
39 1O9P MLA 0.04238 0.40404 4.34783
40 1VE3 SAM 0.0183 0.40245 4.40529
41 5E8J SAH 0.03143 0.40043 4.48718
42 4DMG SAM 0.0009199 0.48092 5.34351
43 3U31 NAD 0.000009346 0.53725 5.51724
44 1LSS NAD 0.0009975 0.45284 5.71429
45 3EGI ADP 0.003426 0.46717 5.82524
46 1P77 ATR 0.04938 0.40421 5.88235
47 2PXX SAH 0.005893 0.42186 6.51163
48 5MF6 7M2 0.0002992 0.44391 6.62252
49 5MF6 AR6 0.0002992 0.44391 6.62252
50 4KXQ APR 0.0001717 0.40039 6.66667
51 1S7G NAD 0.0004903 0.41224 6.71937
52 1S7G APR 0.001411 0.40266 6.71937
53 3ZG6 APR 0.00004177 0.41373 6.75676
54 1KYQ NAD 0.01772 0.40616 6.93431
55 3EGV SAH 0.007513 0.42376 7.08661
56 4JX1 CAH 0.03605 0.42362 7.10383
57 5LE1 6UW 0.02315 0.43198 7.14286
58 2QQF A1R 0.00009828 0.41824 7.14286
59 3MMH SME 0.02044 0.41696 7.18563
60 1SZD APR 0.0007775 0.4177 7.40741
61 5FA8 SAM 0.003431 0.42269 7.45342
62 1FWV SGA MAG FUC 0.04834 0.40188 7.46269
63 1EFV AMP 0.00001828 0.49996 7.61905
64 1EFV FAD 0.00001828 0.49996 7.61905
65 1M2K APR 0.0001036 0.42461 7.63052
66 2EJU SAH 0.01616 0.40495 7.67196
67 1PNO NAP 0.000353 0.44423 7.77778
68 2OOR TXP 0.0003497 0.45078 8.04598
69 2VDV SAM 0.001912 0.46033 8.13008
70 1P0Z FLC 0.04557 0.40613 8.39695
71 1L3I SAH 0.002788 0.4205 9.89583
72 4JSR 1NQ 0.003586 0.40693 11.2281
73 1WY7 SAH 0.01292 0.40072 11.5942
74 1YC5 NCA 0.0002624 0.45574 11.7886
75 4BUZ NAD 0.0002759 0.45488 11.7886
76 4BUZ OAD 0.0003626 0.44075 11.7886
77 4BUZ OCZ 0.0004926 0.43571 11.7886
78 4RHS SIA SIA GAL 0.04242 0.41163 14.7541
79 1MZC SUC 0.005526 0.45094 16.7539
80 3OFK SAH 0.01233 0.41361 33.7963
81 2C31 TZD 0.03109 0.40927 38.7978
82 2C31 ADP 0.03024 0.40927 38.7978
83 2FKA BEF 0.04915 0.40619 40
84 1T9D FAD 0.000000001255 0.58733 45.9016
85 1T9D P25 0.000000007576 0.42932 45.9016
86 1T9D PYD 0.000000009877 0.4277 45.9016
87 1T9D 1MM 0.00000001044 0.42493 45.9016
88 1YBH FAD 0.0000003703 0.58763 47.9053
89 1V5F TPP 0.00003462 0.56882 47.9053
90 1V5F FAD 0.00003462 0.56882 47.9053
Pocket No.: 2; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: 68
This union binding pocket(no: 2) in the query (biounit: 3eya.bio3) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3HQP FDP 0.02537 0.40947 1.2024
2 5TME UDP 0.02549 0.40139 1.49893
3 1RP7 TZD 0.001354 0.41605 2.36794
4 2QV7 ADP 0.01441 0.40271 2.37389
5 3CV2 COA 0.01574 0.42487 2.44361
6 2FN1 SAL 0.0189 0.41193 2.51716
7 2VZ6 FEF 0.02454 0.40221 2.55591
8 5EK3 5PK 0.03159 0.40044 2.72953
9 3AI7 TPP 0.0001593 0.45743 2.73224
10 3LL5 IP8 0.02098 0.413 2.81124
11 2FN8 RIP 0.03692 0.40178 2.9703
12 1NW4 IMH 0.01427 0.40639 3.26087
13 3WRB GDE 0.01872 0.40434 3.34928
14 3EXH TPP 0.0001246 0.4784 3.40314
15 5KOH HCA 0.02287 0.41618 3.40681
16 4YFB PAC 0.02091 0.40199 3.46084
17 2O1S TDP 0.0002214 0.41329 3.64299
18 1TKB N1T 0.002671 0.42007 4.00729
19 5IFK HPA 0.001534 0.47882 4.48718
20 2C42 PYR 0.0000004958 0.56529 4.55373
21 2C42 TPP 0.0000004958 0.56529 4.55373
22 1VL1 CIT 0.02635 0.40812 4.74138
23 3CTL S6P 0.006026 0.40978 4.7619
24 1R9J TPP 0.000593 0.44191 4.91803
25 2NUO BGC 0.01913 0.40018 4.91803
26 2OZL TPP 0.0001126 0.44631 4.93151
27 1B09 PC 0.0294 0.40443 5.33981
28 1TV5 ORO 0.03617 0.40198 5.41761
29 3SIG AR6 0.003957 0.41438 5.77617
30 5ESO TDP 0.00000001142 0.55033 6.01093
31 5ESO ISC 0.00000001142 0.55033 6.01093
32 3QH2 3NM 0.008414 0.43469 6.33484
33 5DUS APR 0.004106 0.4105 6.54762
34 3BRE C2E 0.01292 0.42585 6.70391
35 1ITZ TPP 0.0006015 0.42857 6.73953
36 5EXE 5SR 0.00000006208 0.55622 6.98413
37 3HWW AKG 0.0001417 0.41692 7.10383
38 4R2I ANP 0.03821 0.40003 7.14286
39 4XDY HIO 0.02306 0.41338 7.39645
40 1G2O IMH 0.01261 0.40542 7.46269
41 5ND5 TPP 0.0004842 0.44552 8.56102
42 2QQD AG2 0.02544 0.4094 9.82143
43 5B48 TDN 0.00000003115 0.56819 9.83607
44 1UMD TDP COI 0.00008458 0.46829 12.2616
45 2YIC TPP 0.0009391 0.41787 12.9326
46 3DVA TPW 0.0002279 0.45128 13.2791
47 1W85 TDP 0.0001513 0.44079 14.2857
48 2X7J TPP 0.00000002372 0.6086 14.3898
49 1QPB PYM 0.000000001191 0.66279 34.6084
50 1QPB TPP 0.000000001191 0.66279 34.6084
51 2VK4 TPP 0.0000000003794 0.67954 34.9727
52 2NXW TPP 0.00000000003675 0.64765 37.7049
53 1UPA TPP 0.000000000008235 0.74525 39.0925
54 2IHT TPP 0.00000000001951 0.73045 39.0925
55 2IHU TP9 0.00000000003077 0.74801 39.6161
56 2VBF TPP 0.000000001325 0.66639 39.7086
57 2UZ1 TPP 0.000000000003814 0.75845 41.8944
58 1ZPD DPX 0.00000000277 0.65354 41.9014
59 4RJK TPP 0.000000000008774 0.71635 43.898
60 1OZH HE3 0.0000000001861 0.48163 45.3552
61 1T9D P22 0.00000002222 0.72598 45.9016
62 1T9D PYD 0.00000002181 0.692 45.9016
63 1T9D P25 0.0000000002562 0.41453 45.9016
64 1T9D FAD 0.0000000002676 0.41436 45.9016
65 1T9D 1MM 0.0000000002826 0.41161 45.9016
66 1V5F TPP 0.03046 0.44774 47.9053
67 1V5F FAD 0.03046 0.44774 47.9053
68 1YBH P22 0.0009123 0.43516 47.9053
Pocket No.: 3; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 3eya.bio3) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 3eya.bio3) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 3eya.bio3) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 3eya.bio3) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 3eya.bio3) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 3eya.bio3) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: 63
This union binding pocket(no: 9) in the query (biounit: 3eya.bio1) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3LST SAH 0.02002 0.41369 1.72414
2 1VMK GUN 0.0307 0.41714 1.80505
3 4MXP DB4 0.01831 0.41208 1.82927
4 4AZW SAM 0.003873 0.4301 2.12314
5 3L8G GMB 0.03039 0.41579 2.13904
6 3JWH SAH 0.001974 0.46429 2.30415
7 3UDG TMP 0.01029 0.44405 2.32558
8 1IM8 SAI 0.01308 0.40326 2.45902
9 3BXO SAM 0.001391 0.4671 2.51046
10 2P69 PLP 0.02274 0.42459 2.61438
11 2YX1 SFG 0.009742 0.42559 2.67857
12 3CQ5 PMP 0.04551 0.40238 2.71003
13 1EU1 GLC 0.03423 0.41098 2.91439
14 3RKR NAP 0.004834 0.44924 3.05344
15 2JJQ SAH 0.01362 0.41842 3.05882
16 4P4M D3T 0.02995 0.41211 3.1746
17 3LGS ADE 0.03849 0.41232 3.37079
18 2EFJ SAH 0.01418 0.41073 3.38542
19 1G60 SAM 0.01003 0.41141 3.46154
20 1ZQ9 SAM 0.005461 0.42674 3.50877
21 4WBD CIT 0.03648 0.4101 3.51201
22 5LKC FUC GLA A2G 0.04003 0.40672 3.57143
23 4A6D SAM 0.01584 0.40239 3.68272
24 1SQF SAM 0.009782 0.41505 3.7296
25 1FP1 SAH 0.006467 0.43049 3.76344
26 1LCF OXL 0.01454 0.42957 3.82514
27 3PMA SCR 0.03276 0.4063 3.861
28 2IZ1 ATR 0.02894 0.42193 4.00844
29 3I9U DTU 0.04661 0.40719 4.18251
30 3CQL NAG 0.02362 0.41733 4.52675
31 1UAY ADN 0.003666 0.44645 4.54545
32 2CJZ PTR 0.0411 0.4059 4.59016
33 3GXO SAH 0.0219 0.40492 4.60705
34 2RI1 GLP 0.04953 0.40554 4.68085
35 1ZGA SAH 0.007167 0.43215 4.91803
36 1EJ0 SAM 0.01098 0.41274 5
37 3ABI NAD 0.004415 0.40197 5.20548
38 3LCC SAH 0.001868 0.45221 5.53191
39 2BO4 FLC 0.01896 0.42833 5.54156
40 3G89 SAM 0.009522 0.42608 5.62249
41 1JG3 ADN 0.005397 0.42698 5.95745
42 2PT9 S4M 0.007568 0.40261 6.23053
43 3QH2 3NM 0.04822 0.40478 6.33484
44 2O07 MTA 0.004762 0.40563 6.57895
45 2B4G ORO 0.0288 0.41706 6.62461
46 3TKA SAM 0.01025 0.40797 6.62824
47 2NXE SAM 0.006805 0.42233 7.08661
48 2OD9 A1R NCA 0.0003828 0.44288 7.14286
49 2HMT NAI 0.005358 0.41739 7.63889
50 3LN9 FLC 0.01411 0.41823 7.91367
51 3UNN MET GLU ASP TPO GLN ALA ILE ASP 0.04569 0.40012 7.9646
52 3G2O SAM 0.008938 0.41686 8.02676
53 3RFV 15L 0.006121 0.4038 8.2397
54 2VOH CIT 0.0334 0.41622 8.28025
55 1R18 SAH 0.001582 0.44043 8.37004
56 3GEG NAD 0.005611 0.40279 8.50202
57 4NEC SAH 0.01166 0.41816 8.71212
58 2WPB ZZI 0.04967 0.40407 9.21053
59 3F81 STT 0.01205 0.43583 10.3825
60 1XTQ GDP 0.01311 0.40044 11.2994
61 3C3Y SAH 0.01378 0.40513 11.3924
62 3MYZ TFX 0.02323 0.40483 12
63 2Q28 ADP 0.00002288 0.53069 42.0765
Pocket No.: 10; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 3eya.bio1) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: 44
This union binding pocket(no: 11) in the query (biounit: 3eya.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2PYW SR1 0.0288 0.40722 1.66667
2 3H4T UDP 0.006326 0.40568 1.9802
3 1JN2 SFP 0.01755 0.42984 2.1097
4 3OTH TYD 0.01589 0.40073 2.18447
5 4NAE 1GP 0.01925 0.41492 2.22222
6 3LJU IP9 0.0292 0.40929 2.33161
7 1VBH PEP 0.02541 0.41053 2.73224
8 3QPB URA 0.02421 0.41204 2.83688
9 3QPB R1P 0.0254 0.40147 2.83688
10 1RRV TYD 0.007891 0.41131 3.125
11 4C2G ALA ALA ALA ALA 0.02968 0.40183 3.13901
12 1G8S MET 0.01134 0.42726 3.47826
13 4BT5 23B 0.03075 0.40104 3.50195
14 4WBD CIT 0.01211 0.43215 3.51201
15 1MFI FHC 0.01244 0.4273 4.38596
16 5KQA GSH 0.03946 0.40031 4.54545
17 2IYF UDP 0.00758 0.43224 4.57831
18 1VJ7 GPX 0.0004914 0.50027 4.58015
19 2RI1 GLP 0.01909 0.41678 4.68085
20 1KC7 PPR 0.0231 0.40825 4.73588
21 2GUE NAG 0.01618 0.42733 4.91803
22 2XHK AKG 0.01846 0.41676 4.95496
23 1MLD CIT 0.03718 0.40067 5.09554
24 1LYX PGA 0.005985 0.42435 5.64516
25 1U6R IOM 0.02644 0.40281 5.78947
26 5N9X THR 0.04104 0.40253 6.04915
27 2ZL4 ALA ALA ALA ALA 0.0178 0.41941 6.12245
28 3LA3 2FT 0.01936 0.41762 6.17284
29 3QDW NDG 0.03436 0.4003 6.29371
30 3FIU AMP 0.0265 0.40054 6.82731
31 1X9I G6Q 0.01548 0.40837 7.28477
32 5GWE GWM 0.02996 0.40162 7.90123
33 2P4S DIH 0.009932 0.41777 8.31099
34 1UGY GLA GLC 0.02721 0.42257 10.5263
35 1UGY GLA BGC 0.03272 0.41687 10.5263
36 1XVB 3BR 0.01475 0.4133 12.9412
37 1QS0 TDP 0.001396 0.43742 15.2334
38 1WAP TRP 0.01326 0.4044 17.3333
39 3FSJ D7K 0.00005091 0.43971 37.6894
40 2C31 TZD 0.0000003046 0.62599 38.7978
41 2C31 ADP 0.0000002901 0.62599 38.7978
42 3IAE D7K 0.00000000001376 0.67132 41.8944
43 2Q28 TPP 0.00005731 0.47496 42.0765
44 4RJK TDL 0.00000000002635 0.67519 43.898
Pocket No.: 12; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 3eya.bio1) has 35 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 13; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 13) in the query (biounit: 3eya.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 14; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 14) in the query (biounit: 3eya.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 15; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 15) in the query (biounit: 3eya.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 16; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 16) in the query (biounit: 3eya.bio1) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 17; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 17) in the query (biounit: 3eya.bio2) has 35 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 18; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: 15
This union binding pocket(no: 18) in the query (biounit: 3eya.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5U75 SIA GAL NDG FUC 0.02602 0.40416 1.78571
2 2IYA UDP 0.01521 0.40364 2.59434
3 1C1D PHE 0.02167 0.40352 3.09859
4 4ZNO SUC 0.01682 0.4108 3.28358
5 1BGV GLU 0.03048 0.40542 3.64299
6 5T96 79J 0.03801 0.40074 3.80117
7 2R5N TPP 0.0003431 0.41021 3.82514
8 2R5N R5P 0.0003705 0.40903 3.82514
9 2R5N RP5 0.0003507 0.4059 3.82514
10 4EKV BTN 0.01128 0.41361 4.40252
11 2CJZ PTR 0.02551 0.40697 4.59016
12 2BFR ADP 0.004192 0.4055 6.77083
13 1V3S ATP 0.003058 0.42102 6.89655
14 1MAI I3P 0.04025 0.40569 19.8473
15 3VY6 BGC BGC 0.009666 0.43317 21.9858
Pocket No.: 19; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 19) in the query (biounit: 3eya.bio2) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 20; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 20) in the query (biounit: 3eya.bio2) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 21; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 21) in the query (biounit: 3eya.bio2) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 22; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 22) in the query (biounit: 3eya.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 23; Query (leader) PDB : 3EYA; Ligand: FAD; Similar sites found: 10
This union binding pocket(no: 23) in the query (biounit: 3eya.bio2) has 36 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3OBT SLB 0.02202 0.40048 1.84332
2 4NAE 1GP 0.03869 0.41356 2.22222
3 2Z48 NGA 0.01868 0.41618 3.24074
4 2Z48 A2G 0.04725 0.40028 3.24074
5 2BZG SAH 0.02062 0.40004 4.31034
6 3VC1 SAH 0.01328 0.4002 4.48718
7 2IMG MLT 0.04084 0.40596 4.63576
8 2WCU FUC 0.0274 0.41347 4.69799
9 1G8K MGD 0.01036 0.4013 6.01093
10 4PIO AVI 0.004927 0.40013 8.35913
Pocket No.: 24; Query (leader) PDB : 3EYA; Ligand: TDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 24) in the query (biounit: 3eya.bio2) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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