Receptor
PDB id Resolution Class Description Source Keywords
3EA5 2.5 Å NON-ENZYME: SIGNAL_HORMONE KAP95P BINDING INDUCES THE SWITCH LOOPS OF RANGDP TO ADOPT T BOUND CONFORMATION: IMPLICATIONS FOR NUCLEAR IMPORT COMPLEXD YNAMICS HOMO SAPIENS KARYOPHERIN IMPORTIN RAN GTP-BINDING HOST-VIRUS INTERACTNUCLEOTIDE-BINDING NUCLEUS PHOSPHOPROTEIN PROTEIN TRANSPTRANSPORT TRANSPORT PROTEIN
Ref.: KAP95P BINDING INDUCES THE SWITCH LOOPS OF RANGDP T THE GTP-BOUND CONFORMATION: IMPLICATIONS FOR NUCLEA COMPLEX ASSEMBLY DYNAMICS. J.MOL.BIOL. V. 383 772 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP MG A:220;
C:220;
 Valid;
Valid;
 none;
none;
 submit data
315.37 n/a P(=O)...
MG A:221;
C:221;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3EA5 2.5 Å NON-ENZYME: SIGNAL_HORMONE KAP95P BINDING INDUCES THE SWITCH LOOPS OF RANGDP TO ADOPT T BOUND CONFORMATION: IMPLICATIONS FOR NUCLEAR IMPORT COMPLEXD YNAMICS HOMO SAPIENS KARYOPHERIN IMPORTIN RAN GTP-BINDING HOST-VIRUS INTERACTNUCLEOTIDE-BINDING NUCLEUS PHOSPHOPROTEIN PROTEIN TRANSPTRANSPORT TRANSPORT PROTEIN
Ref.: KAP95P BINDING INDUCES THE SWITCH LOOPS OF RANGDP T THE GTP-BOUND CONFORMATION: IMPLICATIONS FOR NUCLEA COMPLEX ASSEMBLY DYNAMICS. J.MOL.BIOL. V. 383 772 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 289 families.
1 3EA5 - GDP MG n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 3EA5 - GDP MG n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 3EA5 - GDP MG n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GDP MG; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP MG 1 1
2 N 0.590909 0.906977
3 CU0 0.583333 0.909091
Similar Ligands (3D)
Ligand no: 1; Ligand: GDP MG; Similar ligands found: 56
No: Ligand Similarity coefficient
1 GDP 0.9797
2 ADP 0.9684
3 GNH 0.9666
4 ADP MG 0.9656
5 GTP 0.9519
6 GDP BEF 0.9507
7 GNP 0.9489
8 GSP 0.9446
9 GCP 0.9412
10 GDP AF3 0.9358
11 7DD 0.9356
12 ADX 0.9338
13 ANP 0.9298
14 9GM 0.9298
15 BEF GDP 0.9271
16 G8D 0.9248
17 ATP 0.9246
18 KG4 0.9232
19 ALF GDP 0.9219
20 ACP 0.9218
21 GDP ALF 0.9217
22 BEF ADP 0.9160
23 DAT 0.9159
24 DGI 0.9144
25 AV2 0.9122
26 M7G 0.9094
27 CA0 0.9093
28 AU1 0.9062
29 8GD 0.9049
30 ADP AF3 0.8983
31 DBG 0.8980
32 IDP 0.8963
33 DTP 0.8952
34 AN2 0.8945
35 5GP 0.8932
36 GJV 0.8925
37 AGS 0.8916
38 SAH 0.8895
39 ADP ALF 0.8883
40 GAP 0.8874
41 G3D 0.8872
42 NWZ 0.8829
43 SRP 0.8781
44 CUU 0.8768
45 8LH 0.8767
46 SAM 0.8767
47 6RE 0.8752
48 8LE 0.8750
49 SSA 0.8731
50 G5A 0.8726
51 A5A 0.8709
52 DAL AMP 0.8686
53 J7C 0.8685
54 Y9Z 0.8681
55 IMU 0.8513
56 NX8 0.8512
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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