Receptor
PDB id Resolution Class Description Source Keywords
3DNJ 1.15 Å EC: 3.-.-.- THE STRUCTURE OF THE CAULOBACTER CRESCENTUS CLPS PROTEASE AD PROTEIN IN COMPLEX WITH A N-END RULE PEPTIDE CAULOBACTER VIBRIOIDES ADAPTOR PROTEIN-PEPTIDE COMPLEX PEPTIDE BINDING PROTEIN
Ref.: THE MOLECULAR BASIS OF N-END RULE RECOGNITION. MOL.CELL V. 32 406 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:1;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
TYR LEU PHE VAL GLN ARG ASP SER LYS GLU C:1;
D:1;
Valid;
Valid;
none;
none;
submit data
350.439 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3DNJ 1.15 Å EC: 3.-.-.- THE STRUCTURE OF THE CAULOBACTER CRESCENTUS CLPS PROTEASE AD PROTEIN IN COMPLEX WITH A N-END RULE PEPTIDE CAULOBACTER VIBRIOIDES ADAPTOR PROTEIN-PEPTIDE COMPLEX PEPTIDE BINDING PROTEIN
Ref.: THE MOLECULAR BASIS OF N-END RULE RECOGNITION. MOL.CELL V. 32 406 2008
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 253 families.
1 3DNJ - TYR LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
2 3G1B - TRP LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
3 3GW1 - PHE GLY GLY n/a n/a
4 3G19 - LEU LEU LEU n/a n/a
5 3GQ1 - TRP LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 3DNJ - TYR LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
2 3G1B - TRP LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
3 3GW1 - PHE GLY GLY n/a n/a
4 3G19 - LEU LEU LEU n/a n/a
5 3GQ1 - TRP LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 173 families.
1 3O2B - PHE ARG SER LYS GLY GLU GLU LEU PHE THR n/a n/a
2 2WA8 Kd = 3.8 uM PHE ARG SER LYS GLY GLU GLU LEU PHE THR n/a n/a
3 3DNJ - TYR LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
4 3G1B - TRP LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
5 3GW1 - PHE GLY GLY n/a n/a
6 3G19 - LEU LEU LEU n/a n/a
7 3GQ1 - TRP LEU PHE VAL GLN ARG ASP SER LYS GLU n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: TYR LEU PHE VAL GLN ARG ASP SER LYS GLU; Similar ligands found: 30
No: Ligand ECFP6 Tc MDL keys Tc
1 TYR LEU PHE VAL GLN ARG ASP SER LYS GLU 1 1
2 GLN LEU ALA 0.553846 0.714286
3 SER LYS TYR GLY LEU GLN ASP 0.534247 0.866667
4 THR GLU ASP ASN ASP ASP ASP LEU TYR GLY 0.522388 0.948718
5 TYR LEU GLY ALA ASN GLY 0.511364 0.795918
6 TYR TRP ALA ALA ALA ALA 0.494505 0.770833
7 MET ASN TYR ASP ILE 0.486842 0.883721
8 PHE LEU SER TYR LYS 0.478723 0.735849
9 PHE LEU ALA TYR LYS 0.478723 0.795918
10 SER LEU LEU LYS LYS LEU LEU LEU ALA 0.473684 0.627451
11 PHE LEU 0.470588 0.8
12 TYR GLN SER LYS LEU 0.461538 0.75
13 ASP ASP LEU TYR GLY 0.453488 0.8125
14 TYR GLY GLY PHE LEU 0.450549 0.795918
15 TYR ASP GLN ILE LEU 0.445652 0.866667
16 TYR GLN PHE 0.444444 0.777778
17 PHE LEU SER THR LYS 0.43617 0.705882
18 PHE ARG TYR LEU GLY 0.43 0.696429
19 GLY LEU TYR ALA SER LYS LEU ALA 0.428571 0.75
20 ALA GLU THR PHE TYR VAL ASP GLY 0.426966 0.863636
21 TRP LEU PHE VAL GLN ARG ASP SER LYS GLU 0.422222 0.708333
22 LYS LEU LEU PHE 0.421687 0.717391
23 ALA ALA SER LEU TYR GLU LYS LYS ALA ALA 0.419048 0.735849
24 VAL TYR 0.414286 0.9
25 SER LEU TYR LEU THR VAL ALA THR LEU 0.41 0.829787
26 ARG LEU ASN PTR ALA GLN LEU TRP HIS ARG 0.405941 0.730769
27 ASP LEU TYR CYS TYR GLU GLN LEU ASN 0.40566 0.735849
28 ALA LEU ASP LEU PHE 0.405063 0.809524
29 GLY ALA ASP ILE PHE TYR LEU ASP GLY ALA 0.4 0.8125
30 TYR VAL ASP GLY ALA 0.4 0.791667
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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