Receptor
PDB id Resolution Class Description Source Keywords
3DAK 2.25 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF DOMAIN-SWAPPED OSR1 KINASE DOMAIN HOMO SAPIENS SERINE/THREONINE PROTEIN KINASE STE20 DOMAIN-SWAPPING ATPKINASE MAGNESIUM METAL-BINDING NUCLEOTIDE-BINDING PHOSPHOPROTEIN POLYMORPHISM SERINE/THREONINE-PROTEIN KINATRANSFERASE
Ref.: CRYSTAL STRUCTURE OF DOMAIN-SWAPPED STE20 OSR1 KINA DOMAIN. PROTEIN SCI. V. 18 304 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:1;
B:1;
C:1;
D:1;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:296;
B:296;
C:296;
D:296;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3DAK 2.25 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF DOMAIN-SWAPPED OSR1 KINASE DOMAIN HOMO SAPIENS SERINE/THREONINE PROTEIN KINASE STE20 DOMAIN-SWAPPING ATPKINASE MAGNESIUM METAL-BINDING NUCLEOTIDE-BINDING PHOSPHOPROTEIN POLYMORPHISM SERINE/THREONINE-PROTEIN KINATRANSFERASE
Ref.: CRYSTAL STRUCTURE OF DOMAIN-SWAPPED STE20 OSR1 KINA DOMAIN. PROTEIN SCI. V. 18 304 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 133 families.
1 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 101 families.
1 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 5DBX - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (663)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3IGO - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 3NCG - BK1 C19 H19 N5 CC(C)n1c2c....
3 3MWU - BK3 C22 H24 N6 c1ccc2c(c1....
4 6NG0 Ki = 10 nM B49 C22 H27 F N4 O2 CCN(CC)CCN....
5 2XF0 ic50 = 30 uM 4UB C15 H11 N5 c1ccc(cc1)....
6 2YM6 ic50 = 0.88 uM YM6 C14 H16 N6 O c1cncc2c1c....
7 6FCK ic50 = 0.031 uM D4Z C20 H22 N4 O c1ccc(cc1)....
8 4QYG ic50 = 0.0041 uM 3DW C22 H21 N5 O2 CN1CCN(CC1....
9 3TKH ic50 = 47 nM 07S C23 H27 N7 O2 S c1cc(cnc1)....
10 2XEZ ic50 = 1.5 uM XEZ C12 H9 N7 c1c[nH]nc1....
11 2HXL ic50 = 12 nM 422 C23 H24 N6 c1cc2c(cc1....
12 5OQ7 Ki = 0.322 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
13 5F4N ic50 = 2.2 nM 5UY C17 H19 N7 O3 COC(=O)c1c....
14 2E9N ic50 = 6.2 nM 76A C29 H27 N3 O3 c1cc(ccc1c....
15 2YM3 ic50 = 1.2 uM YM3 C14 H19 N5 O3 CCOC(=O)c1....
16 2YDI - YDI C16 H20 N4 O3 S CN(C)CCOc1....
17 5OP5 Ki = 0.216 uM 3FE C17 H15 N5 O c1cc(cc(c1....
18 3NLB ic50 = 35 nM 5BE C21 H28 N6 O Cc1c(c([nH....
19 3JVR Ki = 1.89 uM AGX C16 H13 Cl2 N3 O2 C[C@@H](c1....
20 2WMX ic50 = 0.86 uM ZY6 C17 H19 N5 O c1ccc(cc1)....
21 2C3J Ki = 0.659 uM DBQ C11 H11 N5 O2 c1c[nH]c2c....
22 2YM7 ic50 = 0.13 uM YM7 C15 H18 N8 c1c(ncnc1N....
23 2X8I ic50 = 0.19 uM X8I C17 H13 N3 O2 CC1=CC2=NN....
24 2YDJ ic50 = 0.005 uM YDJ C17 H19 F N4 O2 S c1cc(cc(c1....
25 4QYE ic50 = 1.2 uM 3DL C17 H12 N2 O3 c1cc(cc(c1....
26 5OP7 - A1K C19 H21 Cl N6 O3 CNc1c2c(c[....
27 5OOP - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
28 5OPR Ki = 2.56 uM A3E C21 H26 N6 O CC(C)n1cc(....
29 2BRG ic50 = 6.1 uM DFY C21 H19 N3 O2 CN(CCO)c1c....
30 5OQ5 Ki = 0.02 uM 4K4 C31 H38 N8 O3 CN1CCN(CC1....
31 2CGU ic50 = 13.4 uM 3A3 C17 H13 N O7 c1cc-2c(cc....
32 2WMR ic50 = 52 uM ZYR C10 H10 N2 O S C1CCc2c(c3....
33 3PA5 ic50 = 2 nM C73 C17 H19 Cl N4 O2 S c1cc(ccc1c....
34 2WMV ic50 = 9.2 uM ZYV C10 H14 N6 O c1[nH]c2c(....
35 5OQ8 Ki = 1.41 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
36 2CGX ic50 = 15.6 uM 3D3 C7 H8 N6 O S c1nc(c2c(n....
37 4QYF - 3DV C17 H13 N3 O3 c1cc(cc(c1....
38 5OPS Ki = 0.863 uM A3Q C14 H9 N3 O c1cc(cc(c1....
39 3JVS Kd = 0.29 uM AGY C22 H22 N4 O4 CC(C)(C)c1....
40 2WMW ic50 = 0.39 uM ZYW C11 H14 Br N5 O c1c2c(c(cn....
41 2BR1 Ki = 7.2 uM PFP C22 H21 N3 O4 COc1ccc(cc....
42 2C3L Ki = 8.58 uM IDZ C14 H10 N4 c1ccc2c(c1....
43 5OP2 Ki = 0.24 uM A0Q C24 H26 N4 O2 CN1CCN(CC1....
44 2X8E ic50 = 0.014 uM X8E C16 H12 N4 O CC1=CC2=NN....
45 2X8D ic50 = 0.8 uM X8D C11 H9 N3 O CC1=CC2=NN....
46 2YEX ic50 = 0.0001 uM YEX C15 H12 N4 O CC1=CC2=NN....
47 2BRM Ki = 1.3 uM DFZ C20 H18 N4 O c1ccc(cc1)....
48 1NVQ Ki = 5.6 nM UCN C28 H26 N4 O4 C[C@@]12[C....
49 5OOR - STU C28 H26 N4 O3 C[C@@]12[C....
50 3PA4 ic50 = 3 nM C72 C19 H19 Cl N4 O S c1cc(ccc1c....
51 4RVK ic50 = 13.5 nM 3XK C19 H13 N5 O CC(=O)Nc1c....
52 2HOG ic50 = 0.3 nM 710 C24 H25 N7 O c1cc2c(cc1....
53 6FC8 ic50 = 0.012 uM D4Q C19 H19 F N4 O S c1cc(cc(c1....
54 5R98 - SQG C10 H7 F3 N2 O2 c1cc(ccc1N....
55 5RA8 - 2O6 C8 H5 F3 N2 O c1cc2c(cc1....
56 5R9J - LXS C15 H16 N2 O4 CCN1C(=O)C....
57 4EH2 - IRG C17 H16 N4 c1ccc(cc1)....
58 3HA8 - 5JZ C36 H38 N8 O5 CCOc1nc(nc....
59 6Y7W Kd = 57.8 uM OFW C26 H35 N5 O6 S C[C@@]1(CN....
60 3HEG Kd = 0.18 uM BAX C21 H16 Cl F3 N4 O3 CNC(=O)c1c....
61 2ZAZ Ki = 0.4 uM GK1 C20 H15 N3 O2 S Cc1ccc(cc1....
62 5R9R - K3D C9 H17 N3 O2 CCNC(=O)N1....
63 3HP5 - I46 C14 H9 F2 N3 c1cc(ccc1c....
64 5ML5 ic50 = 10 nM 1VI C26 H25 F N4 O3 S COc1ccc(c(....
65 5R93 - SOJ C12 H12 N2 c1ccc(cc1)....
66 4DLI Kd = 2.4 uM IRG C17 H16 N4 c1ccc(cc1)....
67 3P78 ic50 = 0.11 uM P78 C24 H27 N3 O4 S2 CC(C)(C)c1....
68 5R9Y - SU7 C15 H18 N2 O c1ccc(cc1)....
69 4EH9 - IRG C17 H16 N4 c1ccc(cc1)....
70 1YWR ic50 = 32 nM LI9 C27 H29 F N6 O C[C@@H](c1....
71 3IW5 Kd = 0.839 uM DF3 C28 H24 F3 N3 O4 S c1ccc2c(c1....
72 5R9C - 7ZC C12 H16 N2 O CN(C)Cc1c[....
73 3HV3 ic50 = 900 nM R49 C30 H31 N7 O Cc1cccc(c1....
74 6HWV ic50 = 115 nM GEW C32 H28 F2 N6 O3 Cn1c(c(nc1....
75 5R8U - SLS C10 H11 N O2 c1cc2c(cc1....
76 4A9Y - AQZ C32 H37 N7 O4 Cc1ccc(cc1....
77 5R9Q - LVD C8 H10 N2 O2 c1ccc(cc1)....
78 3GCU - R48 C29 H30 N8 O Cc1ccc(cc1....
79 1OUY ic50 = 4.3 nM 094 C24 H18 Cl2 F2 N4 O S c1cc(c(c(c....
80 5R9L - SRJ C18 H25 N O2 c1ccc(cc1)....
81 3D7Z Ki = 12 nM GK5 C22 H24 N2 O2 Cc1ccc(cc1....
82 2YIS - YIS C35 H34 Cl N7 O3 S2 CC(C)(C)c1....
83 1OUK ic50 = 0.13 nM 084 C28 H29 F3 N6 C[C@@H](c1....
84 6YCW - OL8 C15 H10 N2 O4 c1cc(cc(c1....
85 3BV2 ic50 = 0.44 nM P38 C33 H32 N8 O3 Cc1ccc(cc1....
86 4R3C - GG5 C14 H10 F N3 c1cc(ccc1c....
87 4L8M ic50 = 0.001 uM F46 C33 H30 F N3 O5 c1ccc(cc1)....
88 4E6A - 0O9 C32 H65 O10 P CCCCCCCCCC....
89 1WBN ic50 = 0.35 uM L09 C20 H22 Cl N5 O2 CC(C)(C)c1....
90 6ZWR ic50 = 21.7 nM OEB C34 H39 N7 O3 c1ccc(cc1)....
91 2QD9 ic50 = 13 nM LGF C27 H24 F2 N6 O5 COc1c(cc2c....
92 3HUC Kd = 1030 nM G97 C20 H16 N6 O C=CC(=O)Nc....
93 3HL7 Ki = 0.023 uM I47 C20 H20 Cl N5 O2 c1cc(ccc1c....
94 4EHV - IRG C17 H16 N4 c1ccc(cc1)....
95 5R95 - SQ4 C10 H8 N2 O2 c1cc(ccc1N....
96 2GTN ic50 = 4 nM LIE C20 H16 F3 N5 O CC(C)n1c2c....
97 3HRB ic50 = 21 nM I39 C19 H14 F2 N2 O2 Cc1ccccc1c....
98 3BX5 ic50 = 3.5 nM 304 C17 H22 N4 O2 S CC[C@@H](C....
99 5R9V - SSY C10 H8 F3 N O2 CC(=O)c1cc....
100 3HVC ic50 = 600 nM GG5 C14 H10 F N3 c1cc(ccc1c....
101 2GFS ic50 = 0.7 uM PQB C19 H18 F N3 O4 c1cc(cc(c1....
102 5N63 - 8OW C21 H17 F N4 c1ccc(cc1)....
103 2NPQ Kd = 3.08 uM BOG C14 H28 O6 CCCCCCCCO[....
104 3IW6 Kd = 3.29 uM PP0 C23 H31 N3 O3 CCn1c(c(c(....
105 3S4Q ic50 = 4 nM NK0 C25 H23 N5 O2 Cc1ccc(cc1....
106 2BAJ Kd = 4 nM 1PP C20 H20 Cl2 N4 O CC(C)(C)c1....
107 3ROC - 29B C14 H10 F N3 c1cc(ccc1c....
108 5RA7 - SW7 C8 H9 N O Cc1ccc(cc1....
109 5R8Z - SN4 C7 H8 N2 O S COc1ccc(cn....
110 5R9D - N9J C8 H9 N O3 c1ccc(cc1)....
111 5R9P - SFY C11 H11 N3 O2 S c1ccnc(c1)....
112 3NWW ic50 = 7 nM 3NW C24 H34 N8 O S CCNC(=O)NC....
113 1W83 ic50 = 0.065 uM L11 C23 H25 Cl F N3 O3 c1cc(cnc1)....
114 3ZSH - 469 C27 H30 Cl F N4 O3 C[C@@H]1C[....
115 3IPH Ki = 0.0000251 mM G11 C21 H23 N3 O2 Cc1ccc(cc1....
116 5MZ3 ic50 = 0.0002 uM 8EN C24 H19 F3 N4 O2 Cc1ccc(cc1....
117 5R9W - STV C10 H13 N O4 S CCS(=O)(=O....
118 3P7B ic50 = 0.018 uM P7B C25 H28 N4 O3 S CC(C)(C)c1....
119 5RA1 - PO6 C8 H9 N O2 c1ccc(cc1)....
120 3GCQ Kd = 342 nM 1BU C29 H30 N8 O Cc1cccc(c1....
121 5RA5 - SVJ C8 H16 N2 CN1[C@@H]2....
122 5R9E - S7S C7 H13 N5 O CCCC(=O)Nc....
123 4F9Y Ki = 184 nM LM3 C21 H18 N4 CN(C)c1cc(....
124 5R92 - SO7 C14 H18 N2 O4 CN(C(=O)[C....
125 2BAL Kd = 490 nM PQA C21 H21 F N4 O2 c1cc(cc(c1....
126 3HUB Kd = 8.2 nM 469 C27 H30 Cl F N4 O3 C[C@@H]1C[....
127 4F9W Ki = 114 nM LM4 C21 H18 N4 CN(C)c1cc(....
128 3P5K ic50 = 0.076 uM P5K C24 H27 N3 O4 S2 CC(C)(C)c1....
129 2I0H ic50 = 9 nM 222 C27 H19 Cl2 F N4 O3 c1ccc2c(c1....
130 5R9F - SQP C13 H11 N O2 c1ccc(c(c1....
131 1ZYJ ic50 = 1.5 uM BI5 C19 H16 N2 O2 c1ccc(cc1)....
132 6Y7X - OFQ C11 H19 N O C1C2CC3CC1....
133 3K3I - JZJ C18 H16 Br N3 c1ccc2c(c1....
134 1WBT ic50 = 0.34 uM WBT C26 H25 F N4 O2 c1cc(cc2c1....
135 1BMK - SB5 C17 H16 F N5 c1cc(ccc1c....
136 3E92 Ki = 10 nM G6A C21 H21 N3 O2 Cc1ccc(cc1....
137 3P7A ic50 = 0.52 uM P7A C23 H27 N3 O3 S2 CC(C)(C)c1....
138 6ANL ic50 = 240 nM T75 C24 H21 N3 O S CCc1nc(c(s....
139 3NNX ic50 = 11 nM EDD C22 H23 Cl2 N5 O2 CC(C)(C)C1....
140 4EH4 - IRG C17 H16 N4 c1ccc(cc1)....
141 1KV1 Kd = 1.16 uM BMU C15 H19 Cl N4 O CC(C)(C)c1....
142 5R9U - JMM C13 H16 N2 O3 c1cc(oc1)C....
143 3KF7 ic50 = 40 nM L9G C22 H18 F2 N4 O Cc1ccc(cc1....
144 4KIN ic50 = 4.8 nM 1M8 C22 H19 Cl N2 O2 S Cc1ccc(cc1....
145 5R9N - JFS C14 H12 N2 O c1ccc2c(c1....
146 4AA4 ic50 = 9 nM QC0 C25 H25 N5 O3 Cc1ccc(cc1....
147 5RA9 - SWD C6 H3 Cl N2 S c1csc2c1nc....
148 5XYY ic50 = 9.221 uM P0F C15 H12 Cl F N4 O c1cc(cc(c1....
149 5R97 - RUY C7 H12 N4 O C1CCN(CC1)....
150 3E93 Ki = 1.4 nM 19B C30 H32 N4 O3 Cc1ccc(cc1....
151 5R9O - 54F C11 H10 N2 O c1ccnc(c1)....
152 4AAC ic50 = 6.7 nM AAV C24 H24 N6 O3 Cc1ccc(cc1....
153 4AA0 ic50 = 35 nM AA0 C30 H33 N7 O3 Cc1ccc(cc1....
154 1OZ1 ic50 = 6.5 nM FPH C18 H12 F N3 O c1cc2c(c(c....
155 5N64 - 8OH C19 H16 N4 S c1ccc(cc1)....
156 3IW8 Kd = 13.4 uM HIZ C19 H18 Cl F N4 O2 S c1ccc(cc1)....
157 3LFN ic50 = 3160 nM A27 C23 H21 N3 O2 CCCC(=O)Nc....
158 3PY1 Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
159 2A4L ic50 = 0.4 uM RRC C19 H26 N6 O CC[C@H](CO....
160 1Y8Y ic50 = 2 uM CT7 C13 H11 Cl N4 O2 S CS(=O)(=O)....
161 6GUH Kd = 26 nM FB8 C18 H21 N5 O2 S Cc1ncc(n1C....
162 1OIR ic50 = 0.032 uM HDY C23 H26 N6 O2 Cc1c(n2ccc....
163 1PXJ - CK2 C9 H10 N4 S Cc1c(sc(n1....
164 2VTO ic50 = 0.14 uM LZ8 C17 H13 F N4 O2 c1ccc(cc1)....
165 2BTR ic50 = 95 nM U73 C13 H15 N3 O S CC(C)C1=CN....
166 6Q4K - HHW C16 H12 Cl N O3 c1cc(cc(c1....
167 2VTA ic50 = 185 uM LZ1 C7 H6 N2 c1ccc2c(c1....
168 3EZR - EZR C26 H27 N7 O CN1CCN(CC1....
169 3ULI ic50 = 0.07 uM 1N3 C21 H25 Br N6 O2 COc1ccc(cc....
170 2DS1 ic50 = 3.4 nM 1CD C22 H21 N5 O3 C[C@@H]1C[....
171 5FP5 - 1Y6 C7 H5 F O2 c1cc(ccc1C....
172 2VTH ic50 = 120 uM LZ2 C10 H9 N O3 S c1cc2c(ccc....
173 1KE5 ic50 = 560 nM LS1 C16 H15 N3 O3 S CNS(=O)(=O....
174 3FZ1 - B98 C13 H15 N3 O2 S COc1ccc2c(....
175 1WCC ic50 = 350 uM CIG C4 H4 Cl N3 c1c(nc(cn1....
176 1PXO Ki = 2 nM CK7 C14 H12 N6 O2 S Cc1c(sc(n1....
177 1H00 ic50 = 38 uM FAP C21 H23 F2 N5 O2 CN(C)C[C@@....
178 2R3R - 6SC C18 H14 Br N5 c1ccc(cc1)....
179 1B39 Kd = 0.12 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
180 6Q4C - HH8 C8 H5 Br N2 c1cc2c(ccn....
181 3PXF Kd = 37 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
182 3TI1 - B49 C22 H27 F N4 O2 CCN(CC)CCN....
183 2R3G ic50 = 800 nM SC9 C18 H14 F N5 c1ccc(c(c1....
184 2C69 ic50 = 26 uM CT8 C17 H14 Br N6 c1cc(cc(c1....
185 2VTM ic50 ~ 1 mM LZM C7 H4 N4 c1cnc2c(cn....
186 4ERW - STU C28 H26 N4 O3 C[C@@]12[C....
187 1E1V Ki = 12 uM CMG C12 H17 N5 O c1[nH]c2c(....
188 2VV9 ic50 = 0.017 uM IM9 C23 H29 N7 O2 Cc1ncc(n1C....
189 5IEV - R0N C18 H23 F3 N4 O3 S C[C@H]([C@....
190 6Q48 - HHQ C5 H4 I N O C1C(=CC=NC....
191 4D1X - ESJ C11 H8 N2 O3 S2 c1cc2c(cc1....
192 5MHQ - 8QT C19 H27 N7 O CC[C@@H]([....
193 2BTS ic50 = 20 nM U32 C12 H15 N3 O2 S2 CC(C)c1cnc....
194 6Q4D - HHT C9 H9 Br O3 COc1cc(ccc....
195 1URW ic50 < 0.003 uM I1P C21 H24 N8 O2 S CN(C)CCCNS....
196 5FP6 - MFZ C11 H7 Cl2 N O c1cc(c2c(c....
197 1CKP - PVB C20 H25 Cl N6 O3 CC(C)[C@H]....
198 1KE6 ic50 = 5.7 nM LS2 C17 H15 N5 O3 S2 CNS(=O)(=O....
199 2C6K ic50 = 0.73 uM DT2 C17 H21 N7 O2 S c1cc(ccc1N....
200 6Q4F - 26D C5 H7 N3 c1cc(nc(c1....
201 2R3Q - 5SC C19 H16 Br N5 O Cc1ccccc1c....
202 1OIT ic50 < 0.003 uM HDT C17 H14 N6 O2 S c1ccn2c(c1....
203 3NS9 ic50 = 0.003 uM NS9 C20 H27 N5 O3 CC(C)c1cnn....
204 6Q4I - HGK C13 H11 N O4 c1cc(ccc1C....
205 1H01 ic50 = 22 uM FAL C21 H23 Cl2 N5 O2 CN(C)C[C@H....
206 2EXM - ZIP C10 H13 N5 CC(=CCNc1c....
207 4BGH ic50 = 4 nM 3I6 C13 H16 Br N5 O3 S C[C@H](CO)....
208 2R3F ic50 = 500 nM SC8 C18 H13 Cl2 N5 c1cc(c(c(c....
209 1GII - 1PU C17 H16 N4 O2 c1ccnc(c1)....
210 6Q4B - HHN C4 H3 Br N2 c1c(cncn1)....
211 2R64 ic50 = 0.03 uM 740 C23 H27 N5 O3 S c1cc(ccc1C....
212 5A14 - LQ5 C24 H26 F3 N7 O2 CN1CCN(CC1....
213 2C6L ic50 = 0.27 uM DT4 C17 H22 N8 O2 S c1cc(ccc1N....
214 2W06 - FRV C18 H20 N6 O2 S Cc1ncc(n1C....
215 4EZ7 - STU C28 H26 N4 O3 C[C@@]12[C....
216 6Q4J - HHB C12 H11 N3 O2 c1cc(cc(c1....
217 5D1J ic50 = 48 nM 56H C17 H24 N4 O2 S2 CC(C)(C)c1....
218 5IEY - 6AE C14 H19 N5 O3 S C[C@H]([C@....
219 2VTT ic50 = 0.044 uM LZD C16 H17 F2 N5 O2 c1cc(c(c(c....
220 2VU3 ic50 = 0.047 uM LZE C16 H17 Cl2 N5 O2 c1cc(c(c(c....
221 2B54 - D05 C20 H15 Cl3 N4 O3 CCc1c2c(n(....
222 1GZ8 - MBP C10 H13 N5 O2 CC(C)C(=O)....
223 3PY0 ic50 = 0.13 uM SU9 C13 H11 N3 O2 COc1ccc2c(....
224 2VTR ic50 = 1.5 uM LZB C10 H10 Cl N5 CC(C)Nc1cc....
225 1E1X Ki = 1.3 uM NW1 C11 H17 N5 O2 C1CCC(CC1)....
226 3UNJ ic50 = 11 uM 0BX C17 H14 N4 O2 c1ccc(cc1)....
227 2A0C - CK9 C19 H26 N6 O2 CC[C@H](CO....
228 3TIY - TIY C11 H8 O5 c1c2c(c(c(....
229 2R3I ic50 = 1000 nM SCF C18 H14 F N5 c1ccc(c(c1....
230 1VYZ ic50 = 290 nM N5B C13 H13 N3 O c1ccc(cc1)....
231 3WBL ic50 = 23 uM PDY C20 H26 N6 O CCOc1ccc(c....
232 4RJ3 ic50 = 93 nM 3QS C22 H28 N6 O COC1CCN(CC....
233 2VTN ic50 = 0.85 uM LZ7 C12 H11 F N4 O2 CC(=O)Nc1c....
234 1AQ1 - STU C28 H26 N4 O3 C[C@@]12[C....
235 2C6M ic50 = 0.35 uM DT5 C17 H20 N6 O3 S c1cc(ccc1N....
236 2R3L ic50 = 100 nM SCW C18 H14 Br N5 c1ccc(cc1)....
237 6Q4A - HGW C4 H3 I N2 c1c(cncn1)....
238 1H08 - BYP BWP n/a n/a
239 1B38 Kd = 0.254 uM ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
240 2B52 ic50 = 8 nM D42 C21 H23 N7 O2 S Cc1c(sc(n1....
241 1PXL - CK4 C16 H13 F3 N4 S Cc1c(sc(n1....
242 3S2P ic50 = 0.068 uM PMU C17 H22 N4 O3 CC(C)c1cc(....
243 2R3O ic50 = 600 nM 2SC C19 H17 N5 O c1ccc(cc1)....
244 3IGG ic50 = 95 nM EFQ C16 H19 N3 O3 COc1ccc(cc....
245 1R78 ic50 = 3 nM FMD C20 H20 F N3 O4 C[C@H]([C@....
246 2FVD Ki = 0.003 uM LIA C18 H21 F2 N5 O4 S COc1ccc(c(....
247 2VTL ic50 = 97 uM LZ5 C10 H9 N3 O c1ccc(cc1)....
248 1KE9 ic50 = 660 nM LS5 C16 H15 N5 O3 S c1ccc2c(c1....
249 6Q3B - PYZ C3 H3 I N2 c1c(cn[nH]....
250 1PYE Ki = 386 nM PM1 C21 H13 F2 N3 O2 c1ccc(cc1)....
251 6Q49 - HGQ C5 H4 Br N O C1=CNC(=O)....
252 4EZ3 - 0S0 C11 H10 N4 O4 S c1cc(ccc1/....
253 1H07 ic50 = 3 uM MFP C24 H27 Br N6 O2 Cc1ccc(c(c....
254 2B53 ic50 = 0.6 uM D23 C19 H19 F3 N4 CC(C)(C)Nc....
255 6GUK Kd = 715 nM FC8 C19 H24 Cl N7 CCn1cnc2c1....
256 2DUV ic50 = 0.087 uM 371 C19 H17 N O7 S Cc1cc2c(c(....
257 4D1Z - WG8 C13 H10 N2 O3 S c1cc2ccc(n....
258 6Q4E Kd = 350 uM HH5 C5 H4 I N5 c1[nH]c2c(....
259 4ACM Ki = 210 nM 7YG C20 H23 N7 O3 S CN(C)CCNS(....
260 2C5Y ic50 = 0.25 uM MTW C19 H15 N7 O2 c1cc(cc(c1....
261 6Q4G Kd = 50 uM HJK C13 H11 N5 O2 c1cc(cc(c1....
262 2R3K ic50 = 100 nM SCQ C18 H14 Br N5 c1ccc(cc1)....
263 2V0D - C53 C9 H7 N3 O S [H]/N=C1/N....
264 2W1H ic50 = 0.052 uM L0F C17 H13 N5 O c1ccc(cc1)....
265 1Y91 ic50 = 0.059 uM CT9 C23 H33 N7 O2 S CC(C)c1cnn....
266 4FII - ARG PRO LYS PRO LEU VAL ASP PRO n/a n/a
267 4NJD ic50 = 0.79 uM NJD C21 H20 N8 O COc1nc(nc(....
268 4JDK - ARG ARG ARG ARG SER TRP TYR n/a n/a
269 5XVG Ki = 0.009 uM 8FX C20 H22 Cl N7 O C[C@@H]1CN....
270 5VED - STU C28 H26 N4 O3 C[C@@]12[C....
271 2X4Z Kd = 2.7 nM 7KC C25 H30 N8 O S Cc1nc2ccsc....
272 5XVA Ki = 0.051 uM 8FU C18 H20 Cl N7 O Cc1cc(n[nH....
273 2CDZ - 23D C19 H24 Cl N7 CCn1cnc2c1....
274 4JDI - ARG ARG ARG ARG SER TRP TYR n/a n/a
275 6WLX - LYS LYS ARG LEU SER VAL GLU n/a n/a
276 2ZV2 - 609 C19 H10 N2 O3 c1ccc2c(c1....
277 4ONA ic50 = 0.002 uM UW1 C19 H23 N5 O2 CCOc1ccc2c....
278 4JBV ic50 = 0.003 uM V68 C26 H32 N6 O CC(C)COc1c....
279 3NYV - DTQ C16 H15 N3 O3 COc1cc2c(c....
280 3T3U Ki = 0.0025 uM BK6 C22 H24 N6 O COc1ccc2cc....
281 3KU2 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
282 4M84 ic50 = 0.049 uM 21E C17 H19 N5 O CC(C)(C)n1....
283 3HX4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
284 3UPX Ki = 0.0075 uM B6A C20 H22 N4 O c1ccc(cc1)....
285 3SXF Ki = 0.0025 uM BK5 C20 H21 N5 O CCOc1ccc2c....
286 3T3V Ki = 0.003 uM BK4 C19 H19 N5 O CC(C)n1c2c....
287 3I7B ic50 = 0.066 uM BK1 C19 H19 N5 CC(C)n1c2c....
288 3V5P Ki = 0.0011 uM C88 C19 H24 N6 O Cc1cc(ccc1....
289 3V51 - I76 C25 H22 Cl N5 O CC(C)n1c2c....
290 3UPZ - B5A C11 H16 N6 c1c2c(ncnc....
291 3I7C ic50 = 0.018 uM BK2 C19 H19 N5 CC(C)(C)n1....
292 3V5T - UW9 C24 H30 N6 O CCOc1ccc2c....
293 3N51 - BK3 C22 H24 N6 c1ccc2c(c1....
294 6HME - FXB C21 H21 N O3 CC(C)n1c2c....
295 6HOP - FER C10 H10 O4 COc1cc(ccc....
296 5OTO - AQW C24 H23 Cl2 N3 CCc1ccccc1....
297 3AT4 Kd = 2.26 nM CCK C20 H20 N6 O2 CC(C)Nc1cc....
298 3OWJ Ki = 0.86 uM 1EL C17 H14 N2 O2 Cc1c2c(c(c....
299 6RFF ic50 = 0.37 uM K1B C12 H6 Br N5 O4 S c1cc(c(cc1....
300 6EII - B5W C22 H23 Cl N c1ccc(cc1)....
301 5CU0 - 54R C18 H21 Cl N2 O CC(=O)NCCC....
302 5H8E Kd = 6.33 pM 5Y3 C21 H25 N9 O CC(=O)Nc1c....
303 5OWH - B0K C10 H9 Br4 N3 c1nc2c(n1C....
304 6L1Z - E3U C16 H12 O6 c1cc(c(c2c....
305 3WAR - NIO C6 H5 N O2 c1cc(cnc1)....
306 5MOE Kd = 520 uM OQC C11 H10 Cl N O c1cc(c(cc1....
307 5OUE - AVZ C18 H19 Cl N3 c1ccc(cc1)....
308 5MOD Kd = 300 uM 86L C10 H14 Cl N O CC(C)Oc1cc....
309 6RB1 ic50 = 1.37 uM JWQ C14 H9 F3 N4 O3 S COc1cc(ccc....
310 6TEI - N4N C15 H11 N3 O2 S c1ccnc(c1)....
311 5OWL - B0K C10 H9 Br4 N3 c1nc2c(n1C....
312 6HBN - FXB C21 H21 N O3 CC(C)n1c2c....
313 5CU3 Kd = 0.32 uM 54S C26 H26 Cl N3 O4 c1ccc(cc1)....
314 5OTR - AU8 C13 H12 Cl2 N c1ccc(cc1)....
315 4KWP Ki = 0.04 uM EXX C12 H10 Br4 N2 O3 c1nc2c(n1[....
316 5OSL - A9K C13 H12 Cl N O c1ccc(c(c1....
317 5N9N Ki = 0.41 nM KC5 C20 H15 Cl2 N O4 COc1ccc(cc....
318 5CSP Kd = 58 uM 54G C8 H8 O3 Cc1ccc(c(c....
319 5CTP - 54R C18 H21 Cl N2 O CC(=O)NCCC....
320 5MOW - BR9 C5 H6 Br N3 c1c(cnc(c1....
321 4UB7 Ki = 2.5 nM 3G5 C16 H8 Br2 O5 c1cc(ccc1C....
322 5MMF - JMB C16 H19 Cl N CCC[NH2+]C....
323 5OTH - AQ8 C25 H26 Cl N3 O CCc1ccccc1....
324 1PJK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
325 6YPK - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
326 3NSZ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
327 5OTI - AOK C25 H26 Cl N3 CCc1ccccc1....
328 3AXW - TID C9 H7 N3 O2 S c1cc(ccc1c....
329 5MO6 - KXZ C19 H21 Cl N2 O3 c1ccc(cc1)....
330 2PVR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
331 3C13 - EMO C15 H10 O5 Cc1cc2c(c(....
332 5CS6 Kd = 630 uM K82 C10 H14 Cl N O CCCOc1ccc(....
333 6YPH - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
334 3PE2 Ki = 0.175 nM E1B C20 H12 N4 O2 C#Cc1cccc(....
335 5CT0 - 54P C16 H18 Cl N O c1ccc(cc1)....
336 6RCM ic50 = 0.36 uM K0N C17 H18 N4 O3 S CC(C)(C)c1....
337 5CU6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
338 5M4C - 7EY C16 H14 N2 O2 S2 Cc1ccc(cc1....
339 6SPX ic50 = 44 uM DAS ASP ASP ASP ASP ASP LYS 9AB n/a n/a
340 5MO7 - YRA C16 H17 Cl N2 O c1ccc(cc1)....
341 5N9L Ki = 15 nM 8QH C20 H15 Cl2 N O3 Cc1ccc(cc1....
342 5OT5 - AWK C25 H26 Cl N3 CCc1ccccc1....
343 3OWK ic50 = 1.5 uM 18E C16 H11 Cl N2 O Cc1cnc(c2c....
344 5MMR - H83 C17 H21 Cl N2 c1ccc(cc1)....
345 5MPJ - J2P C15 H17 Cl N CC[NH2+]Cc....
346 5OQU - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
347 6GIH - EZN C15 H13 Cl N2 c1cc(c2cc[....
348 6RFE ic50 = 0.28 uM K0Z C13 H9 Br N4 O3 S COc1cc(ccc....
349 6YPG - N5Q C20 H14 N2 O3 S c1ccc2cc(c....
350 5CSV - GAB C7 H7 N O2 c1cc(cc(c1....
351 5MOT - HBD C7 H7 N O2 c1cc(ccc1C....
352 3R0T ic50 = 0.91 nM FU9 C22 H16 F3 N5 O2 c1cc(cc(c1....
353 3PE1 Ki = 0.223 nM 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
354 3JUH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
355 5CLP - 42J C8 H9 Cl2 N c1cc(c(cc1....
356 5ORH Kd = 41 uM A4N C14 H14 Cl N Cc1ccccc1c....
357 3H30 Ki = 29.2 uM RFZ C12 H12 Cl2 N2 O4 c1c2c(cc(c....
358 2ZJW Ki = 0.02 uM REF C14 H6 O8 c1c2c-3c(c....
359 6HOU - V55 C8 H8 O3 COc1cc(ccc....
360 7A4C ic50 = 3.82 uM QWW C5 H Br3 N4 c12c(c(c(n....
361 6YPN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
362 5OSZ - AHK C24 H25 Cl N3 CCc1ccccc1....
363 4GRB ic50 = 17 nM 0XG C19 H18 N4 O4 S CN(C)C(=O)....
364 5OT6 - AJK C19 H20 Cl N2 c1ccc(cc1)....
365 6EHK - AUW C24 H23 Cl2 N3 CCc1ccccc1....
366 6L24 - E3U C16 H12 O6 c1cc(c(c2c....
367 3MB7 ic50 = 200 nM 14I C16 H8 O6 c1cc2c(cc(....
368 5OS8 - J27 C14 H14 Cl F N Cc1cc(ccc1....
369 5OTY - AUW C24 H23 Cl2 N3 CCc1ccccc1....
370 5OTD - AOW C24 H24 Cl N4 O2 CCc1ccccc1....
371 6GMD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
372 5CVF - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
373 6HNY - GHT C19 H19 N O4 CN1CCc2cc(....
374 5CX9 - 551 C20 H23 Cl N2 O3 COC(=O)CC(....
375 5OUL - AWE C13 H11 Cl F N c1cc(cc(c1....
376 4XP0 - 42A C8 H5 N3 c1cc2c(c[n....
377 4QP2 Kd = 940 uM 36R C7 H5 Cl N2 O c1cc2c(cc1....
378 5NHF ic50 < 0.00032 uM 8X5 C23 H25 N5 O2 c1ccc(cc1)....
379 5BUJ ic50 = 0.005 uM 4VB C16 H15 N5 O c1cnccc1c2....
380 6G9J ic50 = 4.1 nM ERK C27 H28 Cl N5 O3 C[C@H](c1c....
381 5BUI ic50 = 0.089 uM 4V9 C17 H15 F N4 c1ccnc(c1)....
382 4QP7 ic50 = 5.9 uM 363 C9 H7 N5 c1c[nH]c2c....
383 3ERK ic50 = 18 uM SB4 C18 H19 F N6 c1cc(ccc1c....
384 6GDQ - EVK C21 H22 Cl2 N4 O2 CC(C)Nc1cc....
385 5V60 - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
386 6QA1 - HVK C5 H6 N2 c1ccnc(c1)....
387 1TVO Ki = 0.14 uM FRZ C18 H13 N7 c1ccc(cc1)....
388 6G9A ic50 = 21 nM ESQ C23 H28 Cl N5 O3 c1cc2c(cc1....
389 5BVD ic50 = 0.16 nM 4VF C24 H26 Cl N5 O3 c1cc(cc(c1....
390 4ZZN ic50 = 0.26 uM CQ8 C18 H21 Cl N4 O2 CNC(=O)c1c....
391 3SA0 - NRA C13 H8 O6 c1c(cc2c(c....
392 4ERK ic50 = 27 uM OLO C15 H18 N6 O Cn1cnc2c1n....
393 6GJD ic50 = 0.022 uM F0E C46 H55 N11 O5 c1cnc(nc1)....
394 5U6I - 81Y C19 H22 N4 O2 CC(C)Oc1cc....
395 5NHV ic50 = 0.0028 uM 8QB C16 H19 N5 O2 c1cnc(nc1c....
396 6QAL - HV2 C3 H6 O3 S C1C(CS1(=O....
397 3I5Z Ki = 2 nM Z48 C24 H23 N5 O2 Cc1cnc(nc1....
398 6QA4 - HRZ C5 H5 N O C1=CC(=O)N....
399 4N0S - DHC C9 H8 O4 c1cc(c(cc1....
400 5NHP ic50 = 0.023 uM 8XK C19 H23 N7 O2 Cn1c(ccn1)....
401 3I60 Ki < 2 nM E86 C24 H22 Cl N5 O2 Cc1cnc(nc1....
402 4XP2 - TT4 C8 H9 N5 c1ccc(cc1)....
403 1PME Ki = 0.76 nM SB2 C21 H16 F N3 O S C[S@](=O)c....
404 6Q7T - HOW C3 H4 N2 O c1conc1N
405 5NHL ic50 < 0.0003 uM 8XB C20 H25 N7 O2 Cc1cnc(nc1....
406 5HD4 - 38Z C33 H33 N9 O2 c1cnc(nc1)....
407 6G97 ic50 = 4.2 nM EQZ C20 H23 Cl N4 O3 COCCN1Cc2c....
408 6G92 ic50 = 76000 nM ERZ C10 H13 N5 Cc1cnc(nc1....
409 5K4I ic50 = 3.1 nM 6QB C21 H18 Cl F N6 O2 Cn1c(ccn1)....
410 3SHE - I85 C24 H22 F3 N5 O2 c1cc(cc(c1....
411 1JNK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
412 5IZJ - 6J9 C10 H13 N5 c1c[nH]c2c....
413 3AG9 Ki = 9 nM A02 C40 H70 N18 O9 [H]/N=C(N)....
414 5IZF Kd = 0.18 nM 6J9 AZ1 DAR ACA DAR NH2 n/a n/a
415 6YPS - P72 C7 H8 N2 O [H]/N=C(c1....
416 6Z44 - IPH C6 H6 O c1ccc(cc1)....
417 6SPU - GAB C7 H7 N O2 c1cc(cc(c1....
418 3DA6 - BZ9 C28 H23 N7 O Cc1cc(c2cc....
419 2R9S ic50 = 0.15 uM 255 C24 H24 N4 O2 S CC(C)(C)NS....
420 4Y5H ic50 = 15 nM 519 C20 H30 N6 O2 CC(C)NC(=O....
421 4X21 Kd = 36 nM 3WH C20 H23 I N6 O CCNC(=O)N1....
422 3RTP ic50 = 7 nM 34I C18 H14 N6 O2 S c1ccc2c(c1....
423 3PZE - CFK C12 H11 N3 O2 S c1ccc(cc1)....
424 4Z9L ic50 = 1.6 nM 880 C27 H34 Cl2 N6 CCCn1c(c(n....
425 4WHZ ic50 < 1 nM 3NL C24 H23 Cl N8 O2 c1ccc(c(c1....
426 4W4Y ic50 = 3034 nM 3HQ C24 H22 N6 O2 Cc1ccc(cc1....
427 4W4W ic50 = 6630 nM 3HJ C23 H20 N6 O2 Cc1cc(ccn1....
428 3G90 Ki = 0.44 uM J72 C17 H12 F2 N2 O4 c1cc2c(cc1....
429 1PMV ic50 = 150 nM 537 C14 H8 N2 O c1ccc2c(c1....
430 2VZ6 - FEF C20 H19 N3 O4 c1ccc2c(c1....
431 2Z7R ic50 ~ 0.4 nM STU C28 H26 N4 O3 C[C@@]12[C....
432 4J8M ic50 = 48 nM CJ5 C26 H25 F3 N8 O c1cc(cc(c1....
433 5ORO - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
434 6HJJ ic50 = 1.7 uM G7T C26 H24 F4 N6 O2 Cc1cc(ccc1....
435 5ORS - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
436 5ORL - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
437 5DR9 - 5E2 C16 H9 Br Cl N O2 c1cc(cc(c1....
438 4DEA ic50 = 256 nM NHI C18 H14 N4 O4 c1cc(ccc1C....
439 5DN3 Kd = 3.77 uM 5DN C16 H9 Br F N O2 c1cc(cc(c1....
440 6C2T - EGJ C27 H26 Cl F N4 O2 S C[C@H]1C[C....
441 5ORP - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
442 4DEE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
443 5OSE Kd = 681 uM A98 C6 H9 N3 O2 S2 CCSc1nnc(s....
444 6R4B - JSN C14 H15 F2 N3 O2 CC1=NC(=O)....
445 5DNR - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
446 6VPJ - GLC GLC n/a n/a
447 6VPL - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
448 3UOD Kd = 49 nM 0C3 C18 H13 F3 N4 O2 c1ccc(c(c1....
449 3EFW - AK8 C25 H21 F3 N6 O2 Cc1cc(ccc1....
450 5DT0 - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
451 3UO4 Kd = 299 nM 0C0 C23 H18 N4 O2 c1ccc(cc1)....
452 3UP2 Kd = 40 nM 0C8 C18 H13 F3 N4 O3 c1ccc(c(c1....
453 5ORX ic50 = 308 uM A6H C11 H8 Cl2 N2 O c1cc(c(c(c....
454 6VPI - MLA C3 H4 O4 C(C(=O)O)C....
455 5ORN - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
456 5OS5 Kd = 410 uM A8K C12 H10 O2 S c1cc(ccc1O....
457 5DR2 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
458 3DJ5 - AK5 C21 H20 Br N5 O3 S COc1ccc(cc....
459 6R4D - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
460 3UOL ic50 = 3.1 nM 0C7 C17 H13 Cl N8 c1ccc(c(c1....
461 3D14 ic50 = 22 nM AK1 C19 H15 F3 N6 O S2 c1cc(cc(c1....
462 5OSD - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
463 5OS2 Kd = 1821 uM A7K C13 H21 N2 O c1ccc(c(c1....
464 4BN1 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
465 2NP8 ic50 = 42 nM CC3 C21 H18 F3 N5 O c1cc(cc(c1....
466 5ORR Kd = 170 uM A5Q C9 H6 F3 N3 S c1cc(ccc1c....
467 4JBQ - VX6 C23 H28 N8 O S Cc1cc([nH]....
468 5OS3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
469 5DRD - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
470 5DPV - SKE C15 H12 F2 N6 O3 S c1cc(c(c(c....
471 5ORZ Kd = 432 uM A6W C10 H9 N O2 S2 COC(=O)c1c....
472 4UYN ic50 = 4 nM Y3M C25 H22 N4 O4 S CCOC(=O)c1....
473 5DT3 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
474 2WTV Ki = 1.8 nM ZZL C25 H15 Cl F2 N4 O2 c1cc(c(c(c....
475 6HJK ic50 = 25 nM G7W C25 H20 F4 N6 O2 CC(C)n1c2c....
476 3O50 - LJE C24 H17 F3 N4 O2 Cc1cc(ccc1....
477 2J4Z ic50 = 65 nM 626 C23 H24 N6 O2 S CN1CCN(CC1....
478 3LAU ic50 = 0.044 uM OFI C17 H17 N3 O2 CCCC(=O)Nc....
479 3DAJ ic50 = 2.9 uM FXG C22 H29 N7 O2 CCCCNC(=O)....
480 4JBO ic50 = 24 nM WPH C31 H32 N6 O3 CN(C)CCOc1....
481 5ORW Kd = 796 uM A6E C13 H16 F N O2 S c1cc(ccc1O....
482 2C6D - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
483 5OS0 Kd = 2792 uM A6Z C12 H15 Cl N3 c1cc(cc(c1....
484 3K5U ic50 = 309 nM PFQ C20 H17 N3 O2 c1ccc(cc1)....
485 3GC9 - B45 C28 H27 Cl3 F N3 O CC(C)N1CCC....
486 4KS7 - 7KC C25 H30 N8 O S Cc1nc2ccsc....
487 4KS8 - B49 C22 H27 F N4 O2 CCN(CC)CCN....
488 6TE2 - N4N C15 H11 N3 O2 S c1ccnc(c1)....
489 6HMB - 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
490 7A22 ic50 = 1.98 uM QWW C5 H Br3 N4 c12c(c(c(n....
491 3OFM - 4B0 C9 H7 Br4 N3 O C(Cn1c2c(c....
492 6HMC - FXB C21 H21 N O3 CC(C)n1c2c....
493 5YF9 - NIO C6 H5 N O2 c1cc(cnc1)....
494 6TGU - N92 C16 H11 Cl N2 O3 S c1cc(ccc1c....
495 4DGN ic50 = 0.35 uM LU2 C15 H10 O6 c1cc(c(cc1....
496 1M2Q - MNX C13 H7 N O6 c1cc(c2c(c....
497 2OXY - K17 C7 H2 Br4 N2 c1[nH]c2c(....
498 1M2R - MNY C14 H10 N2 O4 c1cc(c2c(c....
499 3KXN - K8X C7 H2 I4 N2 c1[nH]c2c(....
500 6QS5 ic50 = 0.57 uM JGB C10 H8 N2 O3 c1cc(c(cc1....
501 1ZOE Ki = 0.04 uM K25 C9 H7 Br4 N3 CN(C)c1[nH....
502 2PVL Ki = 0.024 uM P55 C18 H20 N8 CCN1CCN(CC....
503 1LP4 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
504 2PVN Ki = 0.00035 uM P63 C20 H16 N8 O CC(=O)Nc1c....
505 3KXG - K6X C7 H Br5 N2 c12c(c(c(c....
506 3BE9 Ki = 24 nM P04 C19 H21 N7 O c1cc2cc(c1....
507 2OXX - K22 C7 H2 Br4 N2 S c12c(c(c(c....
508 3KXM - K74 C11 H9 Br4 N3 O S CNC(=O)CSc....
509 1LR4 - BEN C7 H8 N2 [H]/N=C(c1....
510 1OM1 Ki = 0.17 uM IQA C17 H12 N2 O3 c1ccc2c(c1....
511 1ZOH Ki = 0.1 uM K44 C10 H7 Br4 N3 C[N@@]1CCn....
512 2PVK Ki = 0.008 uM P45 C19 H14 Cl N7 c1ccc(cc1)....
513 1DAY - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
514 5BYZ ic50 = 0.042 uM 4WE C25 H32 F N7 O Cc1ncc(n1C....
515 6HKN ic50 = 0.051 uM G9E C22 H21 F3 N4 O3 COc1ccc2c(....
516 4ZSJ ic50 = 2.3 uM 4R0 C13 H17 Cl N6 O Cc1cc(ccc1....
517 4ZSG - 4QX C12 H15 Cl N6 O CC(C)NC(=O....
518 6HKM ic50 = 270 nM G92 C23 H22 F3 N3 O4 COc1cc2c(c....
519 3EH9 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
520 1IG1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
521 5AUW ic50 = 8.9 uM QUE C15 H10 O7 c1cc(c(cc1....
522 5AV2 - KMP C15 H10 O6 c1cc(ccc1C....
523 5AUU ic50 = 21 uM LU2 C15 H10 O6 c1cc(c(cc1....
524 3EHA - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
525 5AV3 - KMP C15 H10 O6 c1cc(ccc1C....
526 5AUT Kd = 6.7 uM 2AN C16 H13 N O3 S c1ccc(cc1)....
527 5AV0 ic50 = 280 uM 47X C15 H10 O5 c1cc(c(cc1....
528 1JKK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
529 3F5U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
530 5AV4 - GEN C15 H10 O5 c1cc(ccc1C....
531 5AUX ic50 = 10 uM KMP C15 H10 O6 c1cc(ccc1C....
532 5AUV ic50 = 31 uM AGI C15 H10 O5 c1cc(ccc1C....
533 2XK6 - EQH C18 H21 N3 O2 S c1csc(c1C2....
534 2W5A - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
535 5M55 ic50 = 0.24 uM 7GG C17 H20 N6 CCN(CC)/C=....
536 6SK9 ic50 = 1.42 uM F9N C23 H33 N7 O3 S CN(C)CCCNS....
537 2XNM ic50 = 0.16 uM WGZ C27 H27 F3 N4 O3 S C[C@H](c1c....
538 2XKF ic50 = 0.87 uM BX1 C19 H24 N4 O5 COc1cc(cc(....
539 2JAV ic50 ~ 8 uM 5Z5 C17 H16 Cl N3 O2 Cc1c([nH]c....
540 5M53 ic50 = 0.62 uM 7GJ C21 H26 N6 O2 CN(C)C(=O)....
541 2XK8 ic50 = 2.4 uM 5R1 C21 H21 N3 O6 COc1cc(ccc....
542 2WQO - VGK C21 H20 N2 O5 COc1cc(cc(....
543 2XKE ic50 = 4.2 uM WI2 C17 H20 N4 O3 COc1cccc(c....
544 2XNN - 430 C21 H16 F3 N3 O2 S C[C@H](c1c....
545 2XK7 ic50 = 1.5 uM 30E C21 H28 N4 O5 CC[C@H]1C[....
546 1Z5M ic50 = 30 nM LI8 C23 H31 Br N8 O3 CC(C)(C(=O....
547 5HKM ic50 = 0.013 uM 61Y C16 H15 N7 CCc1cc(nc(....
548 3QD0 ic50 = 3.16 nM 3Q4 C24 H26 N8 O C[C@@H]1CC....
549 3ORZ - BI4 C27 H26 N4 O2 C[N@]1CCC[....
550 5LVN Kd = 20 uM ADN C10 H13 N5 O4 c1nc(c2c(n....
551 2XCH ic50 = 374 nM CKG C22 H25 N7 O c1c2c(nc(n....
552 4AW0 - MJF C18 H15 Cl O5 c1ccc(cc1)....
553 3OTU - BI4 C27 H26 N4 O2 C[N@]1CCC[....
554 3QCX ic50 = 63 nM 3Q2 C16 H19 N7 O C[C@@H]1CO....
555 1UU3 ic50 = 0.75 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
556 5LVL Kd = 1.25 uM 537 C14 H8 N2 O c1ccc2c(c1....
557 3QC4 ic50 = 0.002 uM MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
558 3QCY ic50 = 20 nM 3Q3 C22 H22 N8 O2 c1ccc(cc1)....
559 1UU8 ic50 = 9 uM BI1 C25 H24 N4 O2 CN(C)CCCn1....
560 4CT1 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
561 4A07 - AZ7 C17 H13 Cl3 N2 O2 c1cc(ccc1[....
562 2X39 ic50 = 2.2 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
563 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
564 4QNA ic50 = 0.023 uM X11 C9 H9 N5 O c1ccc(c(c1....
565 4QMO ic50 = 0.019 uM 34L C13 H8 N4 O S c1cc2c(c3c....
566 4QMW ic50 = 0.086 uM KS1 C17 H17 N7 c1c[nH]c2c....
567 3A7H - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
568 4QML - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
569 4QO9 ic50 = 0.16 uM 627 C26 H30 N6 O3 CN1CCN(CC1....
570 4QMQ ic50 = 0.26 uM 34U C24 H27 N5 O2 COCCOc1ccc....
571 4QMY ic50 = 0.004 uM STU C28 H26 N4 O3 C[C@@]12[C....
572 3A7J - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
573 4W8D - 3JA C14 H16 N6 O Cn1cc(cn1)....
574 4QMN ic50 = 0.003 uM DB8 C26 H29 Cl2 N5 O3 CN1CCN(CC1....
575 4QMS ic50 = 7.4 uM 1N1 C22 H26 Cl N7 O2 S Cc1cccc(c1....
576 4QMV ic50 = 0.023 uM 34W C23 H25 F3 N6 O2 CC(=O)NCC(....
577 3A7I - ADE C5 H5 N5 c1[nH]c2c(....
578 6ISJ - 3NG C19 H12 Cl N3 O2 c1cc(cc(c1....
579 4EL9 - AFE C21 H20 O10 C[C@H]1[C@....
580 5D9L ic50 = 0.024 uM 583 C15 H12 N2 O2 c1cc(ccc1c....
581 6YG2 - 8E8 C25 H26 N6 O2 CCC(=O)N1C....
582 2XK9 ic50 = 0.03 nM XK9 C18 H17 N7 O4 C/C(=NNC(=....
583 2YCS ic50 = 1.36 nM NXP C18 H18 N6 O C/C(=NNC(=....
584 2WTI ic50 = 0.092 uM WTI C18 H15 N3 O3 S c1cc(ccc1c....
585 2YIR ic50 = 0.17 nM YIR C20 H19 N7 O3 [H]/N=C(N)....
586 2XBJ ic50 = 0.003 uM XBJ C23 H27 F N4 O4 CC(C)([C@@....
587 2XM9 ic50 = 0.009 uM LWH C21 H20 N6 O c1ccc2c(c1....
588 2YIQ ic50 = 12.67 nM YIQ C20 H19 N7 O C/C(=NNC(=....
589 2CN5 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
590 3HZT - J60 C22 H27 Cl N4 O2 CCN(CC)CCN....
591 4FG8 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
592 5K00 ic50 = 7 nM 6PV C32 H34 N6 O4 COc1cccc(c....
593 5MAG - 7KC C25 H30 N8 O S Cc1nc2ccsc....
594 5IHC ic50 = 0.013 uM 6BB C20 H21 F N4 O c1ccc(c(c1....
595 2F57 - 23D C19 H24 Cl N7 CCn1cnc2c1....
596 5L2S - 6ZV C27 H32 F2 N8 CCN1CCN(CC....
597 4AUA ic50 = 7.2 uM 4AU C12 H9 N3 O c1ccc2c(c1....
598 6YLC - OXW C20 H19 F N10 CN1CCC(CC1....
599 6BUU - GLY ARG PRO ARG THR THR ZXW PHE ALA GLU n/a n/a
600 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
601 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
602 2WEI ic50 = 3.4 nM VGG C17 H21 N5 Cc1cccc(c1....
603 4EYJ - N61 C20 H23 N5 O2 CC(C)(C)c1....
604 3C0G - 3AM C10 H14 N5 O7 P c1nc(c2c(n....
605 3MFR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
606 4OTI ic50 = 43 nM MI1 C16 H20 N6 O C[C@@H]1CC....
607 6QF4 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
608 6SPW ic50 = 4.5 uM DAS ASP ASP ASP ASP ASP LYS A0Z n/a n/a
609 5ONI - 9YE C23 H25 N O3 CC(C)n1c2c....
610 3WF7 ic50 = 206 nM FS9 C18 H17 F3 N6 O c1cc(cc(c1....
611 4L3J - 5FI C19 H21 F3 N6 CCc1cncnc1....
612 3WF6 ic50 = 33 nM FZ9 C18 H16 N6 c1ccc2c(c1....
613 4AU8 ic50 = 551 nM Z3R C11 H8 N2 O2 S3 c1ccc2c(c1....
614 6B16 Ki = 32 nM C7Y C19 H20 N8 C[C@@H](c1....
615 5DFP Ki = 22 nM 59U C28 H32 Cl N7 O CCN1c2c(cn....
616 3FXZ ic50 = 130 nM FLL C30 H18 Cl F N5 O4 Ru c1ccc(cc1)....
617 5IME Ki = 4.6 nM 6BZ C22 H22 Cl N7 O2 CC1=NC=CN(....
618 4ZY6 Ki = 5 nM 4T6 C18 H17 Cl N8 c1cc2c(c(c....
619 3Q53 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
620 4EQC ic50 = 8 nM XR1 C29 H28 Cl N7 O S CCN1c2c(cn....
621 4ZJJ Kd = 9.9 nM 4OR C24 H29 Cl F N5 O CCN1c2ccc(....
622 5KBR ic50 = 260 nM IPW C22 H20 Cl N5 O c1cc(ccc1C....
623 4ZLO ic50 = 12 uM 4PV C18 H18 F2 N4 CN1CCN(CC1....
624 4ZJI Kd = 340 nM 4OQ C20 H22 Cl F N4 CCN1c2ccc(....
625 5DEY Ki = 3.7 nM 59T C25 H25 Cl N6 O3 Cc1cccc(n1....
626 3Q4Z - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
627 4ZY5 Ki = 26 nM 4T5 C17 H25 N7 c1cnc(nc1N....
628 5JZJ - AN2 C10 H16 N6 O9 P2 c1nc(c2c(n....
629 3SLS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
630 5AX9 ic50 = 8 nM 4KT C24 H24 N4 O3 COc1ccc(cc....
631 2J7T - 274 C28 H30 Cl N5 O4 S Cc1c([nH]c....
632 4JQE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
633 4MWH - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
634 4LFI - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
635 3GGF - GVD C22 H19 N7 c1ccc2c(c1....
636 4U44 ic50 = 0.008 uM 3D9 C17 H13 N5 c1ccc(cc1)....
637 4RVT ic50 = 1.9 uM 3XM C17 H19 N O4 CCCCCC(=O)....
638 4OBO ic50 = 0.077 uM 2QV C14 H10 Cl N3 c1cc(cc(c1....
639 3DAK - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
640 1CM8 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
641 3EQD - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
642 3EQC - AGS C10 H16 N5 O12 P3 S c1nc(c2c(n....
643 3EQI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
644 1QL6 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
645 1PHK - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
646 3M2W ic50 < 0.003 uM L8I C23 H21 F N4 O CN1CC2(C1)....
647 3BHY - 7CP C18 H18 Cl2 N4 O Cn1c2c(ccc....
648 2J90 - IZA C18 H16 F N3 O CC(C)(C)c1....
649 5VJA - DUK C14 H12 Cl N5 O2 S C[C@H](C(=....
650 5A6N ic50 = 52 uM U7E C7 H7 N5 O2 S c1cc(cc(c1....
651 6CMJ ic50 = 5 nM F6J C24 H22 N2 O2 CC(C)Cc1cc....
652 3E7O ic50 = 120 nM 35F C20 H14 N6 O2 c1cc(cc(c1....
653 2VN9 - GVD C22 H19 N7 c1ccc2c(c1....
654 4EJN ic50 = 0.005 uM 0R4 C33 H26 F N7 O2 CC(=O)Nc1c....
655 4WNO ic50 = 160 nM 3RF C20 H19 N7 c1ccc2c(c1....
656 4WNP ic50 = 8 nM 3RJ C22 H20 N8 c1ccc2c(c1....
657 6QAS - 34W C23 H25 F3 N6 O2 CC(=O)NCC(....
658 6MNH - JVD C12 H16 N4 O C[C@H](C(C....
659 5CI7 ic50 = 120 nM 51W C18 H24 I N7 O c1cc(cc(c1....
660 2V7O - DRN C25 H23 N5 O2 S [H]/N=C(/N....
661 2UV2 - GVD C22 H19 N7 c1ccc2c(c1....
662 2JFL - DKI C15 H13 F2 N7 O2 S2 c1cc(c(c(c....
663 3AQV - TAK C24 H25 N5 O c1cc(ccc1c....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ANP; Similar ligands found: 429
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 ADP 0.802632 0.972222
4 AP5 0.802632 0.945205
5 B4P 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 HEJ 0.772152 0.972222
10 AN2 0.769231 0.986111
11 AT4 0.769231 0.933333
12 AQP 0.7625 0.972222
13 5FA 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 APR 0.740741 0.945205
18 AR6 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 AGS 0.731707 0.921053
22 KG4 0.728395 0.92
23 AMP 0.723684 0.944444
24 A 0.723684 0.944444
25 ATF 0.717647 0.933333
26 CA0 0.716049 0.92
27 ADX 0.716049 0.851852
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 45A 0.696203 0.893333
33 AMP MG 0.692308 0.90411
34 HQG 0.681818 0.958904
35 A12 0.679012 0.933333
36 AP2 0.679012 0.933333
37 APC 0.678571 0.933333
38 TAT 0.674419 0.933333
39 T99 0.674419 0.933333
40 A22 0.674157 0.958904
41 SRA 0.670886 0.894737
42 SRP 0.670455 0.883117
43 5AL 0.666667 0.906667
44 8LE 0.666667 0.871795
45 ADP BEF 0.662651 0.917808
46 ADP MG 0.662651 0.917808
47 ADQ 0.659341 0.92
48 A1R 0.659341 0.884615
49 A3R 0.659341 0.884615
50 QA7 0.655556 0.871795
51 JNT 0.652174 0.92
52 8LH 0.651685 0.883117
53 3OD 0.648936 0.92
54 BIS 0.648936 0.909091
55 5SV 0.648352 0.82716
56 V2G 0.647727 0.897436
57 9X8 0.645161 0.896104
58 OAD 0.645161 0.92
59 25L 0.642105 0.958904
60 AMO 0.641304 0.907895
61 ANP MG 0.640449 0.958904
62 8LQ 0.637363 0.883117
63 G5P 0.636364 0.897436
64 DLL 0.634409 0.906667
65 00A 0.634409 0.860759
66 AHX 0.634409 0.897436
67 RBY 0.632184 0.907895
68 ATP MG 0.632184 0.917808
69 APC MG 0.632184 0.893333
70 ADV 0.632184 0.907895
71 ADP PO3 0.632184 0.917808
72 NB8 0.631579 0.897436
73 OZV 0.630435 0.945205
74 8QN 0.630435 0.906667
75 OOB 0.630435 0.906667
76 25A 0.630435 0.945205
77 G3A 0.626263 0.897436
78 BEF ADP 0.625 0.893333
79 4AD 0.623656 0.896104
80 PAJ 0.623656 0.8625
81 LAD 0.621053 0.839506
82 ME8 0.614583 0.819277
83 1ZZ 0.614583 0.819277
84 TXA 0.614583 0.907895
85 GTA 0.613861 0.864198
86 9ZA 0.612903 0.909091
87 9ZD 0.612903 0.909091
88 KMQ 0.612245 0.907895
89 3UK 0.610526 0.894737
90 SON 0.604651 0.907895
91 ALF ADP 0.604396 0.848101
92 VO4 ADP 0.604396 0.92
93 WAQ 0.604167 0.860759
94 B5V 0.604167 0.883117
95 PR8 0.604167 0.829268
96 4UV 0.6 0.871795
97 GAP 0.6 0.87013
98 FYA 0.597938 0.881579
99 PTJ 0.597938 0.873418
100 LMS 0.597561 0.829268
101 UP5 0.596154 0.896104
102 FA5 0.59596 0.883117
103 PAP 0.595506 0.958333
104 A4P 0.59434 0.823529
105 XAH 0.59 0.841463
106 AFH 0.588235 0.8625
107 4UU 0.588235 0.871795
108 9SN 0.585859 0.85
109 2A5 0.58427 0.894737
110 T5A 0.583333 0.821429
111 DQV 0.582524 0.932432
112 NAI 0.580952 0.884615
113 B5M 0.58 0.871795
114 B5Y 0.58 0.871795
115 ITT 0.579545 0.917808
116 ATR 0.577778 0.944444
117 OMR 0.575472 0.831325
118 5AS 0.574713 0.781609
119 YLP 0.571429 0.8
120 48N 0.571429 0.873418
121 AP0 0.570093 0.873418
122 4TC 0.570093 0.873418
123 7D3 0.569767 0.881579
124 ADJ 0.568807 0.831325
125 DAL AMP 0.568421 0.881579
126 GNP 0.568421 0.922078
127 9GM 0.568421 0.922078
128 NAX 0.566038 0.851852
129 DND 0.566038 0.907895
130 6V0 0.566038 0.873418
131 4UW 0.566038 0.839506
132 TXD 0.566038 0.884615
133 ADN 0.565789 0.821918
134 XYA 0.565789 0.821918
135 RAB 0.565789 0.821918
136 AOC 0.564706 0.8
137 7D4 0.561798 0.881579
138 ADP BMA 0.561224 0.894737
139 TYM 0.560748 0.883117
140 TXE 0.560748 0.884615
141 GA7 0.557692 0.883117
142 YLC 0.555556 0.819277
143 YLB 0.555556 0.8
144 L3W 0.555556 0.907895
145 139 0.554545 0.851852
146 5N5 0.551282 0.797297
147 JB6 0.55 0.860759
148 LAQ 0.54717 0.819277
149 F2R 0.544643 0.843373
150 MYR AMP 0.544554 0.797619
151 A4D 0.544304 0.797297
152 5CD 0.544304 0.783784
153 80F 0.54386 0.821429
154 7MD 0.542857 0.864198
155 6AD 0.542553 0.886076
156 A2R 0.541667 0.958904
157 UPA 0.541284 0.884615
158 YLA 0.540541 0.8
159 BTX 0.539823 0.821429
160 COD 0.539823 0.793103
161 G5A 0.537634 0.781609
162 HFD 0.537634 0.921053
163 JSQ 0.537634 0.921053
164 CNA 0.535714 0.907895
165 AYB 0.535714 0.790698
166 3DH 0.535714 0.753247
167 BT5 0.535088 0.811765
168 ATP A 0.533981 0.905405
169 ATP A A A 0.533981 0.905405
170 IOT 0.531532 0.811765
171 MTA 0.53012 0.753247
172 3AM 0.529412 0.90411
173 A3P 0.52809 0.944444
174 NAD 0.526316 0.906667
175 PPS 0.526316 0.851852
176 NO7 0.525773 0.907895
177 EP4 0.52439 0.734177
178 7D5 0.52381 0.855263
179 AMP DBH 0.52381 0.87013
180 J7C 0.522727 0.75
181 H1Q 0.521739 0.88
182 A5A 0.520833 0.809524
183 EAD 0.520661 0.851852
184 TSB 0.520408 0.821429
185 AHZ 0.518519 0.797619
186 M2T 0.518072 0.716049
187 DTA 0.518072 0.766234
188 6RE 0.517241 0.740741
189 A3D 0.517241 0.894737
190 YLY 0.516949 0.790698
191 SSA 0.515464 0.802326
192 NA7 0.514852 0.933333
193 AR6 AR6 0.514019 0.893333
194 ARG AMP 0.514019 0.809524
195 7MC 0.513514 0.843373
196 A2P 0.511111 0.930556
197 VMS 0.510204 0.790698
198 54H 0.510204 0.790698
199 52H 0.510204 0.781609
200 TAD 0.509259 0.8625
201 NAQ 0.508333 0.85
202 A3N 0.505618 0.766234
203 CUU 0.505376 0.945205
204 AV2 0.505155 0.893333
205 53H 0.50505 0.781609
206 5CA 0.50505 0.802326
207 8X1 0.50505 0.755556
208 ARU 0.504951 0.839506
209 ZID 0.504132 0.894737
210 P1H 0.504 0.831325
211 AVV 0.5 0.873418
212 6MZ 0.5 0.905405
213 NAE 0.5 0.871795
214 3AT 0.5 0.945205
215 P5A 0.495146 0.747253
216 NSS 0.49505 0.802326
217 LSS 0.49505 0.764045
218 DSZ 0.49505 0.802326
219 N0B 0.491803 0.8
220 38V 0.491803 0.864198
221 ALF ADP 3PG 0.491071 0.817073
222 AF3 ADP 3PG 0.491071 0.817073
223 NVA LMS 0.490196 0.755556
224 O02 0.489583 0.922078
225 DAT 0.489362 0.881579
226 IMO 0.488889 0.90411
227 ZAS 0.488636 0.792208
228 FDA 0.488372 0.813953
229 NWW 0.487805 0.739726
230 D4F 0.487603 0.819277
231 NAJ PZO 0.487395 0.85
232 4TA 0.487179 0.788235
233 NAD TDB 0.486726 0.893333
234 NAD IBO 0.486726 0.893333
235 LPA AMP 0.486486 0.797619
236 DTP 0.484536 0.881579
237 V3L 0.484536 0.945205
238 GJV 0.483516 0.731707
239 S4M 0.483516 0.651685
240 DZD 0.483051 0.8625
241 2AM 0.482759 0.917808
242 5AD 0.481013 0.726027
243 KAA 0.480769 0.755556
244 GSU 0.480769 0.781609
245 NDE 0.480315 0.907895
246 M24 0.479339 0.851852
247 MAO 0.478261 0.761905
248 DSH 0.477778 0.707317
249 NEC 0.477778 0.727273
250 FAD 0.477273 0.831325
251 FAS 0.477273 0.831325
252 RGT 0.476636 0.933333
253 9K8 0.47619 0.698925
254 0WD 0.474576 0.897436
255 FNK 0.474074 0.786517
256 5X8 0.473684 0.74359
257 6FA 0.473282 0.821429
258 NDC 0.472868 0.85
259 FB0 0.472868 0.786517
260 YSA 0.472222 0.781609
261 LEU LMS 0.471154 0.733333
262 7DD 0.468085 0.958333
263 OVE 0.466667 0.881579
264 NWQ 0.465909 0.72
265 DZ4 0.464646 0.907895
266 MHZ 0.463158 0.701149
267 8PZ 0.462963 0.802326
268 AMP NAD 0.462185 0.881579
269 A3G 0.461538 0.779221
270 N5O 0.461538 0.74359
271 NAJ PYZ 0.459677 0.809524
272 6C6 0.459184 0.858974
273 B1U 0.458716 0.758242
274 LQJ 0.458716 0.893333
275 SFG 0.458333 0.730769
276 7D7 0.45679 0.723684
277 128 0.45614 0.8
278 SFD 0.455224 0.736842
279 DDS 0.454545 0.855263
280 GDP 0.454545 0.896104
281 6IA 0.454545 0.817073
282 NJP 0.453782 0.921053
283 ODP 0.453782 0.886076
284 7DT 0.453608 0.958333
285 J4G 0.45283 0.896104
286 A7D 0.452632 0.75641
287 Z5A 0.452381 0.802326
288 WSA 0.452174 0.790698
289 N5A 0.451613 0.717949
290 7C5 0.45045 0.797468
291 K3K 0.449541 0.782051
292 FAY 0.449275 0.841463
293 NDP 0.449153 0.897436
294 SA8 0.44898 0.690476
295 A5D 0.44898 0.766234
296 71V 0.446809 0.884615
297 GGZ 0.446602 0.804878
298 RFL 0.446043 0.802326
299 2SA 0.445545 0.907895
300 SAH 0.444444 0.725
301 SAI 0.444444 0.716049
302 GP3 0.444444 0.897436
303 PO4 PO4 A A A A PO4 0.443396 0.878378
304 QXG 0.443396 0.77907
305 4YB 0.442478 0.764045
306 QXP 0.442308 0.788235
307 K3E 0.441441 0.772152
308 S7M 0.441176 0.674419
309 SMM 0.441176 0.670455
310 GTP 0.441176 0.896104
311 V47 0.441176 0.763158
312 Y3J 0.440476 0.706667
313 SAM 0.44 0.674419
314 649 0.439655 0.747253
315 12D 0.438596 0.809524
316 A3S 0.4375 0.789474
317 NPW 0.436975 0.864198
318 GCP 0.436893 0.873418
319 EEM 0.435644 0.674419
320 AAT 0.435644 0.690476
321 GNH 0.435644 0.909091
322 ETB 0.435484 0.813953
323 DCA 0.435484 0.804598
324 KOY 0.434783 0.782051
325 N6P 0.433962 0.890411
326 NZQ 0.433333 0.886076
327 TXP 0.433333 0.897436
328 PGS 0.43299 0.860759
329 APU 0.432203 0.871795
330 PUA 0.432 0.8625
331 62F 0.431655 0.841463
332 F2N 0.431507 0.795455
333 DA 0.430108 0.855263
334 D5M 0.430108 0.855263
335 J7V 0.429688 0.813953
336 0T1 0.428571 0.804598
337 A3T 0.428571 0.8
338 COA 0.428571 0.804598
339 NIA 0.428571 0.848101
340 6K6 0.428571 0.905405
341 P5F 0.427586 0.804598
342 R2V 0.425926 0.788235
343 CZF 0.425743 0.906667
344 NX8 0.425743 0.698795
345 AAM 0.425532 0.944444
346 KYB 0.424528 0.714286
347 0UM 0.424528 0.682353
348 8Q2 0.423729 0.775281
349 G1R 0.423077 0.884615
350 AMZ 0.422222 0.891892
351 C2R 0.422222 0.88
352 QBQ 0.421569 0.883117
353 IDP 0.42 0.894737
354 K2W 0.419643 0.722892
355 KY2 0.419048 0.714286
356 GSP 0.419048 0.851852
357 1DG 0.418605 0.897436
358 COS 0.418605 0.786517
359 CAO 0.418605 0.777778
360 DG1 0.418605 0.897436
361 30N 0.418605 0.736842
362 AMX 0.418605 0.813953
363 KY5 0.418182 0.707317
364 TM1 0.418182 0.797619
365 9BG 0.418033 0.873418
366 A6D 0.416667 0.746988
367 K15 0.416667 0.666667
368 V1N 0.415929 0.893333
369 SCO 0.415385 0.804598
370 CMX 0.415385 0.804598
371 GEK 0.415094 0.719512
372 NHD 0.414634 0.881579
373 XNP 0.414634 0.851852
374 K38 0.414414 0.759494
375 9JJ 0.413793 0.841463
376 AIR 0.413793 0.876712
377 COK 0.413534 0.786517
378 K2K 0.412844 0.719512
379 G2R 0.412844 0.8625
380 KY8 0.412844 0.710843
381 FAM 0.412214 0.786517
382 FCX 0.412214 0.777778
383 ACO 0.412214 0.777778
384 KL2 0.411111 0.815789
385 NAP 0.410853 0.92
386 NWZ 0.41 0.686747
387 CNV FAD 0.409722 0.775281
388 FA9 0.409396 0.843373
389 SXZ 0.409091 0.694118
390 K2R 0.409091 0.857143
391 O05 0.409091 0.823529
392 HAX 0.409091 0.806818
393 TAP 0.407692 0.884615
394 62X 0.407407 0.651685
395 2MC 0.407407 0.752688
396 K2H 0.407407 0.7375
397 GKE 0.40708 0.8625
398 GDD 0.40708 0.8625
399 GDC 0.40708 0.8625
400 KYE 0.40708 0.697674
401 FYN 0.406015 0.804598
402 3KK 0.406015 0.786517
403 NVA 2AD 0.405941 0.740741
404 KXW 0.405172 0.690476
405 PLP AAD 0.404762 0.736264