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Receptor
PDB id Resolution Class Description Source Keywords
3D6T 2.43 Å EC: 2.7.11.1 STRUCTURE OF THE ROC DOMAIN FROM THE PARKINSON'S DISEASE-ASS LEUCINE-RICH REPEAT KINASE 2 REVEALS A DIMERIC GTPASE HOMO SAPIENS PARKINSON-prime S DISEASE LRRK2 ROC ROCO GTPASE KINASE ATP-BDISEASE MUTATION GTP-BINDING GTPASE ACTIVATION LEUCINE-RREPEAT MEMBRANE NUCLEOTIDE-BINDING PARKINSON DISEASE SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: STRUCTURE OF THE ROC DOMAIN FROM THE PARKINSON'S DISEASE-ASSOCIATED LEUCINE-RICH REPEAT KINASE 2 REV DIMERIC GTPASE PROC.NATL.ACAD.SCI.USA V. 105 1499 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP B:1;
Valid;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG B:2;
Invalid;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZEJ 2 Å EC: 2.7.11.1 STRUCTURE OF THE ROC DOMAIN FROM THE PARKINSON'S DISEASE-ASS LEUCINE-RICH REPEAT KINASE 2 REVEALS A DIMERIC GTPASE HOMO SAPIENS PARKINSON-prime S DISEASE LRRK2 ROC GTPASE ROCO KINASE ATP-BDISEASE MUTATION GTP-BINDING GTPASE ACTIVATION LEUCINE-RREPEAT MEMBRANE NUCLEOTIDE-BINDING PARKINSON DISEASE SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: STRUCTURE OF THE ROC DOMAIN FROM THE PARKINSON'S DISEASE-ASSOCIATED LEUCINE-RICH REPEAT KINASE 2 REV DIMERIC GTPASE PROC.NATL.ACAD.SCI.USA V. 105 1499 2008
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 117 families.
1 3D6T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2ZEJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 91 families.
1 3D6T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2ZEJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 3D6T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2ZEJ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 161
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 9GM 0.839506 0.973684
6 GNP 0.839506 0.973684
7 G 0.828947 0.986486
8 5GP 0.828947 0.986486
9 G1R 0.82716 0.986667
10 GCP 0.82716 0.973684
11 GSP 0.817073 0.948718
12 GAV 0.797619 0.961039
13 GMV 0.792683 0.973684
14 G2P 0.77381 0.961039
15 G2R 0.770115 0.961039
16 GP2 0.756098 0.961039
17 GDC 0.747253 0.961039
18 GKE 0.747253 0.961039
19 GDD 0.747253 0.961039
20 GPG 0.741573 0.961039
21 G3D 0.732558 0.986486
22 ALF 5GP 0.729412 0.888889
23 Y9Z 0.728261 0.902439
24 G5P 0.723404 0.973684
25 GFB 0.72043 0.961039
26 GTG 0.72043 0.936709
27 GDR 0.72043 0.961039
28 G4P 0.715909 0.986486
29 G3A 0.712766 0.973684
30 6CK 0.712766 0.936709
31 GDP AF3 0.7 0.888889
32 ALF GDP 0.7 0.888889
33 GDP ALF 0.7 0.888889
34 YGP 0.698925 0.901235
35 GKD 0.697917 0.961039
36 JB2 0.697917 0.961039
37 GDX 0.690722 0.973684
38 GPD 0.690722 0.925
39 GMP 0.684211 0.88
40 0O2 0.666667 0.986486
41 JB3 0.656863 0.948718
42 NGD 0.650485 0.961039
43 DGI 0.636364 0.923077
44 GDP 7MG 0.636364 0.911392
45 U2G 0.634615 0.936709
46 GPX 0.634409 0.946667
47 G G 0.632653 0.948052
48 IDP 0.632184 0.972973
49 2MD 0.632075 0.891566
50 CAG 0.62963 0.880952
51 CG2 0.622642 0.936709
52 FEG 0.619048 0.879518
53 MGD 0.614679 0.891566
54 ZGP 0.613208 0.869048
55 GH3 0.612903 0.973333
56 3GP 0.611765 0.946667
57 MD1 0.607143 0.891566
58 PGD 0.59292 0.925
59 DGT 0.591398 0.923077
60 BGO 0.588785 0.924051
61 TPG 0.582609 0.840909
62 DBG 0.582609 0.948718
63 2GP 0.574713 0.96
64 FE9 0.570175 0.776596
65 GCP G 0.56 0.921053
66 A G 0.553571 0.935065
67 G A A A 0.553571 0.923077
68 MGP 0.553191 0.961039
69 U A G G 0.548673 0.935065
70 G4M 0.548387 0.880952
71 6G0 0.547368 0.961039
72 G1R G1R 0.542373 0.924051
73 P2G 0.527473 0.883117
74 PGD O 0.525 0.850575
75 ADP 0.522222 0.92
76 R5I 0.520833 0.946667
77 R7I 0.520833 0.946667
78 GGM 0.517544 0.901235
79 DGP 0.516484 0.910256
80 DG 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G U 0.513274 0.9
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 AKW 0.504425 0.890244
86 G C 0.504348 0.9
87 GPC 0.491525 0.879518
88 G7M 0.483871 0.948052
89 6AD 0.479592 0.841463
90 ATP 0.473684 0.92
91 HEJ 0.473684 0.92
92 G2Q 0.471154 0.961039
93 5FA 0.46875 0.92
94 AQP 0.46875 0.92
95 GTA 0.468468 0.936709
96 7DD 0.468085 0.906667
97 G G G RPC 0.466102 0.875
98 SGP 0.463158 0.82716
99 01G 0.462963 0.902439
100 HFD 0.459184 0.873418
101 B4P 0.457447 0.894737
102 AP5 0.457447 0.894737
103 A2D 0.456522 0.894737
104 6YZ 0.455446 0.896104
105 G G G C 0.455285 0.9125
106 5GP 5GP 0.454545 0.883117
107 ANP 0.454545 0.896104
108 ACQ 0.454545 0.896104
109 AT4 0.452632 0.884615
110 A G C C 0.451613 0.911392
111 APC G U 0.45082 0.886076
112 PRT 0.449541 0.959459
113 G U34 0.449153 0.888889
114 DG DG 0.448598 0.865854
115 ITT 0.447917 0.868421
116 BA3 0.446809 0.894737
117 C2E 0.444444 0.921053
118 PCG 0.444444 0.933333
119 35G 0.444444 0.933333
120 MGO 0.441176 0.864198
121 AN2 0.4375 0.907895
122 G C C C 0.4375 0.924051
123 M33 0.43299 0.883117
124 UCG 0.429688 0.911392
125 A G U 0.42963 0.888889
126 ACP 0.428571 0.896104
127 MGQ 0.424528 0.935897
128 AR6 0.424242 0.894737
129 7DT 0.424242 0.906667
130 APR 0.424242 0.894737
131 93A 0.42268 0.833333
132 A4P 0.420168 0.869048
133 G8D 0.42 0.875
134 AD9 0.42 0.896104
135 SAP 0.42 0.873418
136 AGS 0.42 0.873418
137 CA0 0.418367 0.896104
138 ATF 0.417476 0.884615
139 AGO 0.414634 0.888889
140 A G U U 0.414286 0.888889
141 NIA 0.413043 0.82716
142 MGV 0.412844 0.890244
143 TAT 0.411765 0.884615
144 T99 0.411765 0.884615
145 ADQ 0.411215 0.871795
146 A1R 0.411215 0.839506
147 RGT 0.410714 0.909091
148 CGP 0.409836 0.86747
149 C1Z 0.409091 0.986486
150 A 0.408602 0.893333
151 AMP 0.408602 0.893333
152 UP5 0.40678 0.873418
153 AMZ 0.406593 0.918919
154 C2R 0.406593 0.906667
155 JBT 0.405882 0.778947
156 A22 0.40566 0.907895
157 25L 0.405405 0.907895
158 ADX 0.40404 0.809524
159 8OD 0.401961 0.946667
160 50T 0.4 0.883117
161 4TC 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZEJ; Ligand: GDP; Similar sites found with APoc: 654
This union binding pocket(no: 1) in the query (biounit: 2zej.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 3T12 GDP ALF None
2 3T1O GDP None
3 3MD0 GDP None
4 1GXU 2HP None
5 1NJF ADP None
6 1NJF AGS None
7 3VX3 ADP None
8 1DAK ADP None
9 1DAK DPU None
10 2O66 FLC None
11 2ZX2 RAM None
12 3PQC GDP 1.63043
13 3BOS CDP 1.63043
14 3ZS9 ADP ALF 1.63043
15 2WOJ ADP ALF 1.63043
16 4Z7X 3CX 1.63043
17 4R43 GDP 1.75719
18 3W5J GDP 2.17391
19 3G5N PB2 2.17391
20 3Q9L ATP 2.17391
21 2C9O ADP 2.17391
22 1T3D CYS 2.17391
23 2HIM ASP 2.17391
24 2HIM ASN 2.17391
25 1P72 ADP 2.17391
26 3AB4 THR 2.24719
27 2VOH CIT 2.54777
28 3WYA GDP 2.71739
29 2DPY ADP 2.71739
30 4V03 ADP 2.71739
31 4IEE AGS 2.71739
32 1U0J ADP 2.71739
33 1IHU AF3 2.71739
34 1IHU ADP 2.71739
35 5J1J ANP 2.71739
36 1QF5 RPL 2.71739
37 1QF5 GDP 2.71739
38 2ZPA ADP 2.71739
39 5CDH TLA 2.71739
40 3HU3 AGS 2.71739
41 4U60 SIA GAL NGA 2.71739
42 4U60 SIA 2.71739
43 2PL3 ADP 3.26087
44 4E03 ADP 3.26087
45 2GDJ ANP 3.26087
46 4KBF AMP 3.26087
47 3FKQ ATP 3.26087
48 3ZQ6 ADP ALF 3.26087
49 1Q19 SSC 3.26087
50 6AIC AMP 3.26087
51 1VKJ A3P 3.26087
52 3FYH ADP 3.26087
53 1G41 ADP 3.26087
54 4X8O AP5 3.26087
55 5N69 ADP 3.26087
56 3H86 AP5 3.26087
57 1T5C ADP 3.26087
58 5D63 FUC GLA GLA 3.26087
59 4JLS 3ZE 3.28947
60 2GJ8 ALF GDP 3.48837
61 5NM7 GLY 3.7594
62 1GOJ ADP 3.80435
63 4LC1 GDP 3.80435
64 2VVG ADP 3.80435
65 5H7J GCP 3.80435
66 2XT3 ADP 3.80435
67 3H4S ADP 3.80435
68 3COB ADP 3.80435
69 5H7K GDP 3.80435
70 6A20 ADP 3.80435
71 3DKP ADP 3.80435
72 3ZFD ANP 3.80435
73 5ZBR ANP 3.80435
74 1D2E GDP 3.80435
75 1SVI GDP 3.80435
76 1XP8 AGS 3.80435
77 5Y6N ADP 3.80435
78 3BER AMP 3.80435
79 3QF7 ANP 3.80435
80 4LIK CIT 3.80435
81 5GLN XYP XYP XYP 3.80435
82 1F9V ADP 3.80435
83 3DC4 ADP 3.80435
84 4FRZ ADP 3.80435
85 2NCD ADP 3.80435
86 5G3Y ADP 3.80435
87 3TMK T5A 3.80435
88 4MKF AP5 3.80435
89 1UKZ ADP 3.80435
90 1S3G AP5 3.80435
91 1SVM ATP 3.80435
92 4MKG AP5 3.80435
93 2P3V SRT 3.80435
94 1OFH ADP 4.02299
95 3QXC ATP 4.13223
96 1BG2 ADP 4.34783
97 2W58 ADP 4.34783
98 2IYL GDP 4.34783
99 2Y65 ADP 4.34783
100 5U32 GDP 4.34783
101 2FH5 GTP 4.34783
102 1NRJ GTP 4.34783
103 5GVR LMR 4.34783
104 1TAD ALF 4.34783
105 1TAD GDP 4.34783
106 2ZFI ADP 4.34783
107 5LB3 ADP 4.34783
108 4ZNL BEF ADP 4.34783
109 1DAR GDP 4.34783
110 3EZ2 ADP 4.34783
111 1IWE IMP 4.34783
112 5Z69 AGS 4.34783
113 1X6V ADP 4.34783
114 4RZ3 ADP 4.34783
115 1OYY AGS 4.34783
116 2X7I CIT 4.34783
117 5XOY LYS 4.34783
118 2YOH WMJ 4.34783
119 5H4S RAM 4.34783
120 2QZ4 ADP 4.34783
121 2JK0 ASP 4.34783
122 2J0B UDP 4.34783
123 2OZE AGS 4.69799
124 3P13 RIP 4.86111
125 4J0Q GDP 4.8913
126 5W75 GDP 4.8913
127 5KUT GDP 4.8913
128 2X77 GDP 4.8913
129 4PPF FLC 4.8913
130 1JJV ATP 4.8913
131 6AU6 GDP 4.8913
132 2ZR9 DTP 4.8913
133 3EWA ANP 4.8913
134 1XKV ATP 4.8913
135 1XX6 ADP 4.8913
136 2CHG ANP 4.8913
137 5VGR GDP 4.8913
138 5W75 SUC 4.8913
139 5ZB0 ADP 4.8913
140 5ZB0 TYD 4.8913
141 3IUY AMP 4.8913
142 3RC3 ANP 4.8913
143 1YTM ATP 4.8913
144 2Q2Y ADP 4.8913
145 2Q2Y MKR 4.8913
146 4IOK XPO 4.8913
147 4TTQ ATP 4.8913
148 4IOK ADP 4.8913
149 1NN5 2DT 4.8913
150 1NN5 ANP 4.8913
151 4NU0 AP5 4.8913
152 1OS1 ATP 4.8913
153 1OS1 PYR 4.8913
154 1YXM ADE 4.8913
155 4P3Y GDP 5.07614
156 3U6B GDP 5.07614
157 3U6K GDP 5.07614
158 4PC3 GDP 5.07614
159 5JBQ GDP 5.07614
160 4G5G GDP 5.07614
161 1D8T GDP 5.08906
162 2BVN GNP 5.08906
163 2B4B COA 5.26316
164 4JLV ADP 5.43478
165 2D2F ADP 5.43478
166 1H65 GDP 5.43478
167 3KJI ADP 5.43478
168 3TK1 GDP 5.43478
169 2CE7 ADP 5.43478
170 5IFS ADP 5.43478
171 5FJJ MAN 5.43478
172 4QOS ADP 5.43478
173 5I0H ADP BEF 5.43478
174 1NY5 ADP 5.43478
175 2FNA ADP 5.43478
176 4ZDJ UTP 5.43478
177 1G3Q ADP 5.43478
178 1K6M AGS 5.43478
179 1ION ADP 5.43478
180 2BEK ATP 5.43478
181 5E5U MLI 5.43478
182 3KC1 2T6 5.43478
183 1NST A3P 5.43478
184 5W7Q GDP 5.63003
185 1HTW ADP 5.6962
186 2HCJ GDP 5.97015
187 5CK5 GDP 5.97826
188 1RRC ADP 5.97826
189 4AG5 ADP 5.97826
190 4KFU ACP 5.97826
191 3B5J 12D 5.97826
192 5WC2 ADP 5.97826
193 1FP6 ADP 5.97826
194 4IHQ ADP 5.97826
195 1XMV ADP 5.97826
196 3DZD ADP 5.97826
197 5FTB ANP 5.97826
198 6C90 ADP 5.97826
199 1VHT BA3 5.97826
200 4R2I ANP 5.97826
201 5HR5 ADP 5.97826
202 4PJ3 ANP 5.97826
203 4A4Z ANP 5.97826
204 3UIE ANP 5.97826
205 3BFV ADP 5.97826
206 5EXT ADP 5.97826
207 1CR1 TTP 5.97826
208 4OHY ANP 5.97826
209 5FHD ADP ALF 5.97826
210 2KIN ADP 6
211 5MVR ADP 6.17284
212 1KK1 GNP 6.52174
213 2AWN ADP 6.52174
214 2WJG GDP 6.52174
215 5GOE GDP 6.52174
216 3E70 GDP 6.52174
217 2CBZ ATP 6.52174
218 1M7G AV2 6.52174
219 2OG2 MLI 6.52174
220 4M9Q GNP 6.52174
221 3B9Q MLI 6.52174
222 5ZXD ATP 6.52174
223 4ZKD GDP 6.52174
224 1G6O ADP 6.52174
225 3VMF GTP 6.52174
226 5XDR ADP 6.52174
227 3WXM GTP 6.52174
228 5L3V GDP 6.52174
229 1IN4 ADP 6.52174
230 2OFW ADX 6.52174
231 1E2K TMC 6.52174
232 3RLF ANP 6.52174
233 5UIV ADP 6.52174
234 3FSY SCA 6.52174
235 1M7G ADX 6.52174
236 4GOX A3P 6.52174
237 1M7G ADP 6.52174
238 4HSE ADP 6.52174
239 1Z83 AP5 6.52174
240 2PEZ DAT 6.70391
241 2PEZ GGZ 6.70391
242 1KO8 6PG 6.85714
243 1B0U ATP 6.87023
244 3KTA AP5 6.93642
245 4QM7 GTP 7.01754
246 1B7T ADP 7.05128
247 1SKQ GDP 7.06522
248 4RD0 GDP 7.06522
249 3AB3 GDP 7.06522
250 1FQJ GDP 7.06522
251 3CX8 GSP 7.06522
252 1FQK GDP 7.06522
253 1ZCB GDP 7.06522
254 4LYA ATP 7.06522
255 5HCN GCP 7.06522
256 2D7D ADP 7.06522
257 2XAU ADP 7.06522
258 4XGU ADP 7.06522
259 6B4K ANP 7.06522
260 5LTJ BEF 7.06522
261 6FAA ADP 7.06522
262 3T34 GDP 7.06522
263 6CS8 F9Y 7.06522
264 1L2T ATP 7.06522
265 4Q1A 2XZ 7.06522
266 4Q1A UDP 7.06522
267 1UJ2 ADP 7.06522
268 1UJ2 C5P 7.06522
269 5LTJ ADP 7.06522
270 3Q85 GNP 7.10059
271 2WJH FLC 7.22892
272 2WJH GDP 7.22892
273 1G7C 5GP 7.44681
274 5FG3 GDP 7.6087
275 2WIC GNP 7.6087
276 4LPS GDP 7.6087
277 2PZE ATP 7.6087
278 4WZ6 ATP 7.6087
279 3DEF GDP 7.6087
280 4H1V GNP 7.6087
281 1OXV ANP 7.6087
282 1PUJ GNP 7.6087
283 1WDT GTP 7.6087
284 1MKY GDP 7.6087
285 1BH2 GSP 7.6087
286 4P4T GDP 7.6087
287 5L3S GNP 7.6087
288 1SQ5 ADP 7.6087
289 2FSH ANP 7.6087
290 5L3W GDP 7.6087
291 4KVA GTP 7.6087
292 2IXE ATP 7.6087
293 4WEI GLC GAL 7.6087
294 5IRN ADP 7.6087
295 1ZIN AP5 7.6087
296 4OI4 ATP 7.6087
297 3P4X ADP 7.6087
298 5I34 GDP 7.6087
299 1RJW ETF 7.6087
300 1KC7 PPR 7.6087
301 1QF9 ALF 7.6087
302 1QF9 C5P 7.6087
303 1QF9 ADP 7.6087
304 5L3S G 7.6087
305 6C0B MLI 7.69231
306 1KK8 BEF ADP 7.91367
307 6G14 G4P 8.15217
308 5YT0 GDP 8.15217
309 1JJ7 ADP 8.15217
310 1YQT ADP 8.15217
311 5YV5 ADP 8.15217
312 3TBK ANP 8.15217
313 3B7G ANP 8.15217
314 6DEF GCP 8.15217
315 4YJ1 ADP 8.15217
316 4U8P UDP 8.15217
317 2O0J ADP 8.15217
318 3FB4 AP5 8.15217
319 3R7F CP 8.15217
320 5VHC BEF ADP 8.15217
321 1ZUI SKM 8.33333
322 6B8B ADP 8.43373
323 1G6H ADP 8.69565
324 3LRE ADP 8.69565
325 5TSH ADP 8.69565
326 5TSH ANP 8.69565
327 2WHX ADP 8.69565
328 5IRR GSP 8.69565
329 2JLR ANP 8.69565
330 5X40 ACP 8.69565
331 1R6B ADP 8.69565
332 1LVK MNT BEF 8.69565
333 3NHB ADP 8.69565
334 2ZTS ADP 9.16335
335 4R98 GNH 9.23913
336 1F6B GDP 9.23913
337 4YDS ATP 9.23913
338 2RCN GDP 9.23913
339 3FWY ADP 9.23913
340 5M04 GDP 9.23913
341 4B47 GDP 9.23913
342 2FAH GDP 9.23913
343 3IO3 ADP 9.23913
344 5K5Z ANP 9.23913
345 1D2N ANP 9.23913
346 1GOT GDP 9.58904
347 4WOP CTP 9.77778
348 4HI0 GDP 9.78261
349 4D81 ADP 9.78261
350 2J5V PCA 9.78261
351 4ZG4 VO4 ADP 9.78261
352 2J5V RGP 9.78261
353 1YRB GDP 10.3261
354 1GP2 GDP 10.3261
355 2ODE ALF GDP 10.3261
356 6CRK GDP 10.3261
357 1Y3A GDP 10.3261
358 1CS4 GSP 10.3261
359 5KDO GDP 10.3261
360 1SVK ALF GDP 10.3261
361 2BO4 FLC 10.3261
362 1Y63 ADP 10.3261
363 1P9B GDP 10.3261
364 1G7S GDP 10.8696
365 1R0X ATP 10.8696
366 5BQ5 ADP BEF 10.8696
367 5G41 AP5 10.8696
368 1XEX ATP 11.0465
369 1BO4 COA 11.3095
370 5W76 GDP 11.413
371 2C77 GNP 11.413
372 2XTN GTP 11.413
373 4NCN GTP 11.413
374 4TMZ GSP 11.413
375 2C78 GNP 11.413
376 5L3R GCP 11.413
377 2OBM ADP 11.413
378 4WZA ADP 11.413
379 4WZA ACP 11.413
380 3CNL GNP 11.9565
381 2XTZ GSP 11.9565
382 1RJ9 GCP 11.9565
383 4LJ9 ACP 11.9565
384 4FCW ADP 11.9565
385 2HF9 GSP 11.9565
386 4XTR ATP 11.9565
387 4XVU ATP 11.9565
388 4XTR ADP 11.9565
389 1QHG ATP 11.9565
390 1QHH ATP 11.9565
391 2GK6 ADP 12.5
392 3ZIA ATP 12.6984
393 3ZIA ADP 12.6984
394 3QKT ANP 13.0435
395 5XKT GNP 13.5
396 3EC1 GDP 13.587
397 4U00 ADP 13.587
398 4CVN ADP 13.587
399 1JI0 ATP 13.587
400 5BN3 ADP 13.587
401 1M2O GNP 13.587
402 1Z6T ADP 13.587
403 1V8K ANP 14.1304
404 1W7J ADP BEF 14.1304
405 1AKY AP5 14.1304
406 2ZJ5 ADP 14.1304
407 2QTV GNP 14.2857
408 3A1S GDP 14.6739
409 1W5T ADP 14.6739
410 2GKS ADP 14.6739
411 1W5T ANP 14.6739
412 3IIJ ADP 15
413 4PX9 ADP 15.2174
414 1TQ4 GDP 15.2174
415 1W0J ADP 15.2174
416 2CK3 ANP 15.2174
417 2V7Q ADP 15.2174
418 5MZN ADP 15.2174
419 1W0J ADP BEF 15.2174
420 2V7Q ATP 15.2174
421 2I4I AMP 15.2174
422 2CK3 ADP 15.2174
423 4QRH 0O2 15.7609
424 5H67 ATP 16.25
425 3A4M ADP 16.3043
426 5M7P ADP 16.3043
427 2B8W ALF 5GP 16.3043
428 1F5N GNP 16.3043
429 2OM2 GDP 16.6667
430 1F2U ATP 16.7785
431 4YS0 ADP 16.8478
432 3FVQ ATP 16.8478
433 4V0K GDP 17.7515
434 1FZQ GDP 17.9348
435 1LVG ADP 17.9348
436 4ZI2 GNP 17.9348
437 4GOJ GNP 17.9348
438 1KSH GDP 17.9348
439 4BQS K2Q 18.1818
440 4BQS ADP 18.1818
441 2QN6 GDP 18.2796
442 1FNN ADP 18.4783
443 3T5G GDP 18.7845
444 3AQ4 GDP 19.0217
445 2VB6 ADP BEF 19.0217
446 4PFO ADP 19.0217
447 5DI3 GNP 19.5652
448 1MR3 G3D 20.442
449 1UPT GTP 20.4678
450 5EE5 GTP 20.4678
451 1O3Y GTP 20.4819
452 2J59 GTP 20.4819
453 1J2J GTP 20.4819
454 2J0V GDP 20.6522
455 2CDN ADP 20.6522
456 4U5X GNP 20.7865
457 1RE0 GDP 21.3415
458 1S9D GDP 21.3415
459 2IS6 ADP 21.7391
460 2QEN ADP 21.7391
461 1R4A GNP 21.8182
462 3WY9 GDP 21.875
463 4YLG GDP 21.9653
464 1ZJ6 G3D 22.2826
465 2A5F GTP 22.2857
466 4KAX GTP 22.4852
467 4BAS GNP 22.8261
468 1YZG GDP 22.905
469 2W83 GTP 23.0303
470 3PCR GTP 23.4568
471 3N5C GDP 24.0741
472 4YMU ATP 25
473 1WF3 GNP 27.1739
474 5KSP GDP 27.8947
475 5KSZ GCP 28.2609
476 3Q72 GNP 28.3133
477 2CJW GDP 29.3478
478 1M7B GTP 29.3478
479 1GWN GTP 29.3478
480 3REF GDP 29.3478
481 2W2X GSP 30.9783
482 1E96 GTP 30.9783
483 2HT6 GDP 31.0345
484 6BSX GDP 31.4607
485 6BSX E7S 31.4607
486 1DS6 GDP 31.5217
487 2G77 GDP 32.0652
488 4NON GDP 32.0652
489 2A9K GDP 32.6087
490 1Z06 GNP 32.6087
491 5OEC GDP 32.7869
492 4KVG GTP 33.3333
493 4HDO GNP 33.5329
494 4HDQ GNP 33.5329
495 3X1Z GNP 33.5329
496 4DKX GDP 33.6957
497 2F9L GDP 33.6957
498 5LEF GTP 33.6957
499 1ZC3 GNP 33.7143
500 2GCO GNP 34.2391
501 5JCP GDP ALF 34.2391
502 2BME GNP 34.2391
503 2A5J GDP 34.2391
504 3RWO GDP 34.2391
505 2GCN GDP 34.2391
506 3CPJ GDP 34.2391
507 1KMQ GNP 34.2391
508 1UAD GNP 34.2857
509 1S8F GDP 34.4633
510 1Z08 GNP 34.7059
511 4D0N GDP 34.7826
512 3LXR GDP 34.7826
513 5HPY GDP 34.7826
514 5IRC GDP 34.7826
515 3DOE GTP 34.7826
516 6BCB GSP 34.7826
517 6BCA GSP 34.7826
518 6BC0 GSP 34.7826
519 1OW3 GDP 34.7826
520 4XOI GTP 35
521 5WDR GNP 35.0877
522 1CXZ GSP 35.1648
523 1VG1 GDP 35.3261
524 1VG9 GDP 35.3261
525 5TB5 GDP 35.3261
526 1VG0 GDP 35.3261
527 5TAR GDP 35.3261
528 5UQW GDP 35.3261
529 1VG8 GNP 35.3261
530 5OCG GNP 35.3261
531 1KAO GDP 35.3293
532 1U8Z GDP 35.7143
533 4XSH GSP 35.7542
534 2Y8E GNP 35.7542
535 1ZD9 GDP 35.8696
536 1X1R GDP 35.9551
537 1Z0K GTP 36.0465
538 1TX4 ALF GDP 36.1582
539 5Z2M GTP 36.3636
540 1D5C GDP 36.4198
541 1Z0A GDP 36.7816
542 3TKL GTP 36.9565
543 6FA4 GNP 36.9942
544 3SFV GDP 37.0166
545 1Z0J GTP 37.0588
546 1KY3 GDP 37.3626
547 2FFQ GSP 37.4269
548 1Z0F GDP 37.4302
549 5SZH GNP 37.5
550 2EFE GNH 37.5691
551 1YZQ GNP 37.6471
552 4D0G GTP 37.7143
553 1YVD GNP 37.8698
554 1TU3 GNP 38.0117
555 1OIX GDP 38.0435
556 1NF3 GNP 38.0435
557 4DID GDP 38.0435
558 3MJH GTP 38.0952
559 2C5L GTP 38.1503
560 1R2Q GNP 38.2353
561 5O2T GSP 38.4615
562 1A4R GNH 38.587
563 1A4R GDP 38.587
564 1GRN GDP 38.587
565 4ITR GDP 38.587
566 1OIV GDP 38.587
567 2WMO GTP 38.587
568 2NGR GDP 38.587
569 1GRN AF3 38.587
570 4K81 GTP 38.5965
571 4YC7 GNP 38.674
572 1G16 GDP 38.8235
573 5O74 GDP 38.8889
574 1LFD GNP 38.9222
575 3QBT GNP 39.0805
576 4LHW GNP 39.0805
577 3TNF GNP 39.0805
578 5WLB GNP 39.1566
579 5E95 GDP 39.2857
580 1EK0 GNP 39.4118
581 3NKV GNP 39.4286
582 6D5J GNP 39.521
583 6BVJ GNP 39.521
584 6D59 GNP 39.521
585 6D5L GNP 39.521
586 6BVK GNP 39.521
587 6D5E GNP 39.521
588 6BVI GNP 39.521
589 6BVL GNP 39.521
590 6BVM GNP 39.521
591 6D55 GNP 39.521
592 6D56 GNP 39.521
593 6D5H GNP 39.521
594 6D5M GNP 39.521
595 6D5V GNP 39.521
596 6D5G GNP 39.521
597 5JCZ GDP 39.6648
598 4DCT GDP 39.6739
599 1CLU DBG 39.759
600 2UZI GTP 39.759
601 1NVV GNP 39.759
602 3DDC GNP 39.759
603 1WQ1 GDP 39.759
604 1WQ1 AF3 39.759
605 1Z2A GDP 39.881
606 4LX0 BEF GDP 40.113
607 2HV8 GTP 40.6977
608 3M1I GTP 40.7609
609 3WYF GTP 40.7609
610 4C4P GNP 41.0405
611 3WYG GTP 41.2088
612 3SBD GNP 41.3043
613 2WKQ GTP 41.3043
614 1G4U GDP 41.3043
615 3GJX GTP 41.8478
616 1MH1 GNP 41.8478
617 2D7C GTP 41.9162
618 3GJ0 GDP 42.3913
619 3GJ3 GDP 42.3913
620 5BXQ GDP 42.3913
621 3CH5 GDP 42.3913
622 1I4D GDP 42.3913
623 5UWQ GNP 42.3913
624 5UWO GNP 42.3913
625 5UWR GNP 42.3913
626 5UWT GNP 42.3913
627 5UWS GNP 42.3913
628 5UWJ GNP 42.3913
629 5UWP GNP 42.3913
630 5UWH GNP 42.3913
631 5UWI GNP 42.3913
632 5UWU GNP 42.3913
633 1IBR GNP 42.3913
634 4HAT GNP 42.3913
635 5DHF GNP 42.3913
636 6CIT GNP 42.3913
637 5UWW GNP 42.3913
638 5DIF GNP 42.3913
639 5DI9 GNP 42.3913
640 1RYH GNP 42.3913
641 3RAB GNP 42.6035
642 2FJU GSP 43.2584
643 1HE1 GDP 43.75
644 3E5H GNP 43.8202
645 3GJ4 GDP 44.0217
646 3GJ7 GDP 44.0217
647 3GJ5 GDP 44.0217
648 2BCG GDP 44.0217
649 3GJ8 GDP 44.0217
650 1YZN GNP 44.0217
651 1WA5 GTP 44.3182
652 3BC1 GNP 45.1087
653 2EW1 GNP 47.2826
654 5XC5 GTP 48.8636
Pocket No.: 2; Query (leader) PDB : 2ZEJ; Ligand: GDP; Similar sites found with APoc: 9
This union binding pocket(no: 2) in the query (biounit: 2zej.bio1) has 27 residues
No: Leader PDB Ligand Sequence Similarity
1 1ZEI CRS None
2 5J1S ATP 4.06504
3 4OWK NGA 4.34783
4 3NOJ PYR 4.8913
5 1VBH PEP 7.6087
6 1I0B PEL 8.15217
7 5OCQ CIT 10.8696
8 3W9F I3P 14.6739
9 2XZ9 PYR 23.913
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