Receptor
PDB id Resolution Class Description Source Keywords
3CZN 1.4 Å EC: 3.2.1.114 GOLGI ALPHA-MANNOSIDASE II (D204A NUCLEOPHILE MUTANT) IN COM GNMAN5GN DROSOPHILA MELANOGASTER HYDROLASE GLYCOSYL HYDROLASE MANNOSIDASE N-TERMINAL ALPHADOMAIN THREE HELIX BUNDLE 2 C-TERMINAL BETA BARRELS GLYCGOLGI APPARATUS MEMBRANE METAL-BINDING SIGNAL-ANCHOR TRANSMEMBRANE
Ref.: GOLGI ALPHA-MANNOSIDASE II CLEAVES TWO SUGARS SEQUE IN THE SAME CATALYTIC SITE. PROC.NATL.ACAD.SCI.USA V. 105 9570 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
M5G A:1103;
Valid;
none;
submit data
1235.1 C46 H78 N2 O36 CC(=O...
NAG A:1101;
Invalid;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
ZN A:1102;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3EJR 1.27 Å EC: 3.2.1.114 GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH 5-SUBSTITUED SWAI ANALOG: (5R)-5-[2'-OXO-2'-(4-TERT-BUTYLPHENYL)ETHYL]-SWAINS DROSOPHILA MELANOGASTER GH38 GLYCOSIDASE GLYCOSIDASE GOLGI APPARATUS HYDROLASE MMETAL-BINDING SIGNAL-ANCHOR TRANSMEMBRANE
Ref.: STRUCTURAL INVESTIGATION OF THE BINDING OF 5-SUBSTI SWAINSONINE ANALOGUES TO GOLGI ALPHA-MANNOSIDASE II CHEMBIOCHEM V. 11 673 2010
Members (46)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2OW7 ic50 = 14 uM NK2 C8 H15 O2 S C1CC[S@@+]....
2 3D51 Ki = 70 uM GOX C6 H12 N2 O5 C([C@@H]1[....
3 3CV5 - M5S C30 H52 O26 C([C@@H]1[....
4 3EJS ic50 = 250 nM HN5 C20 H31 N O3 CC(C)(C)c1....
5 3DX0 Ki = 36 nM MSN C6 H13 N O3 S CS[C@@H]1[....
6 2FYV ic50 = 0.3 mM W72 C11 H21 N O9 C1[C@H]([C....
7 3BVW - WZ4 C33 H57 N O25 S CC(=O)N[C@....
8 3D4Z Ki = 13 uM GIM C8 H13 N2 O4 c1c[n+]2c(....
9 1TQU ic50 ~ 7.5 mM GHA C9 H18 N O9 S C1C([C@@H]....
10 3DDG Ki = 1 uM GB7 C14 H20 N2 O4 CN1[C@@H](....
11 1PS3 Ki = 5.2 mM KIF C8 H12 N2 O6 C([C@@H]1[....
12 3DX2 Ki = 150 nM MZB C6 H13 N O4 S C[S@@](=O)....
13 2F7O Ki = 0.036 uM MSN C6 H13 N O3 S CS[C@@H]1[....
14 3D52 Ki = 520 uM GHR C13 H16 Cl N3 O6 c1cc(ccc1N....
15 1TQV ic50 ~ 7.5 mM SSE C9 H18 O9 S Se C1[C@H]([C....
16 3EJU ic50 = 250 nM HN7 C20 H29 N O4 CC(C)(C)c1....
17 1HXK ic50 = 400 uM DMJ C6 H13 N O4 C1[C@H]([C....
18 1TQS - SSO C9 H18 O9 S2 C1[C@H]([C....
19 3CZN - M5G C46 H78 N2 O36 CC(=O)N[C@....
20 2OW6 ic50 = 2 mM NK1 C8 H15 O3 S C1C[C@@H](....
21 3BUP - MAN C6 H12 O6 C([C@@H]1[....
22 3EJT ic50 = 44 nM HN6 C20 H31 N O3 CC(C)(C)c1....
23 3CZS - MAN C6 H12 O6 C([C@@H]1[....
24 3DX1 Ki = 265 uM YHO C5 H11 N O3 C1[C@H]([C....
25 2F7P Ki = 0.249 uM 2SK C13 H19 N O3 S CS[C@@H]1[....
26 3EJP Ki = 2.8 nM HN2 C16 H21 N O4 c1ccc(cc1)....
27 3BVV - WZ3 C19 H34 O15 S CO[C@H]1[C....
28 2F18 ic50 = 80 uM GB1 C13 H20 N2 O3 c1ccc(cc1)....
29 3DX4 Ki = 76 nM GOO C6 H13 N O4 CO[C@@H]1[....
30 2F1A ic50 = 720 uM GB2 C13 H20 N2 O3 c1ccc(cc1)....
31 3D4Y Ki = 2 uM MVL C8 H12 N2 O4 c1cn2c(n1)....
32 3DDF Ki = 67 uM GB6 C13 H18 N2 O4 c1ccc(cc1)....
33 1TQT ic50 ~ 7.5 mM SSD C9 H18 O9 S2 C1[C@H]([C....
34 3DX3 Ki = 300 nM YTB C5 H11 N O4 C1([C@H]([....
35 3BUQ - MAN C6 H12 O6 C([C@@H]1[....
36 3EJR Ki = 2.7 nM HN4 C20 H29 N O4 CC(C)(C)c1....
37 1R34 ic50 = 0.9 mM LKS C14 H20 N2 O4 S [H]/N=C(/C....
38 3BVX - WZ5 C33 H57 N O26 CC(=O)N[C@....
39 1HWW ic50 = 20 nM SWA C8 H15 N O3 C1C[C@H]([....
40 3EJQ Ki = 2.7 nM HN3 C17 H23 N O4 Cc1ccc(cc1....
41 3D50 Ki = 17 uM OEV C15 H29 N O4 CCCCCCCCN[....
42 2F1B ic50 = 1000 uM GB3 C14 H22 N2 O3 C[C@@H]1[C....
43 1R33 ic50 = 0.07 mM LKA C6 H13 N O4 S C([C@@H]1[....
44 1TQW ic50 ~ 7.5 mM BLT C9 H18 O9 S Se C1[C@H]([C....
45 3BVT - WZ1 C13 H24 O10 S CO[C@@H]1[....
46 3BVU - WZ2 C19 H34 O15 S CO[C@@H]1[....
70% Homology Family (46)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2OW7 ic50 = 14 uM NK2 C8 H15 O2 S C1CC[S@@+]....
2 3D51 Ki = 70 uM GOX C6 H12 N2 O5 C([C@@H]1[....
3 3CV5 - M5S C30 H52 O26 C([C@@H]1[....
4 3EJS ic50 = 250 nM HN5 C20 H31 N O3 CC(C)(C)c1....
5 3DX0 Ki = 36 nM MSN C6 H13 N O3 S CS[C@@H]1[....
6 2FYV ic50 = 0.3 mM W72 C11 H21 N O9 C1[C@H]([C....
7 3BVW - WZ4 C33 H57 N O25 S CC(=O)N[C@....
8 3D4Z Ki = 13 uM GIM C8 H13 N2 O4 c1c[n+]2c(....
9 1TQU ic50 ~ 7.5 mM GHA C9 H18 N O9 S C1C([C@@H]....
10 3DDG Ki = 1 uM GB7 C14 H20 N2 O4 CN1[C@@H](....
11 1PS3 Ki = 5.2 mM KIF C8 H12 N2 O6 C([C@@H]1[....
12 3DX2 Ki = 150 nM MZB C6 H13 N O4 S C[S@@](=O)....
13 2F7O Ki = 0.036 uM MSN C6 H13 N O3 S CS[C@@H]1[....
14 3D52 Ki = 520 uM GHR C13 H16 Cl N3 O6 c1cc(ccc1N....
15 1TQV ic50 ~ 7.5 mM SSE C9 H18 O9 S Se C1[C@H]([C....
16 3EJU ic50 = 250 nM HN7 C20 H29 N O4 CC(C)(C)c1....
17 1HXK ic50 = 400 uM DMJ C6 H13 N O4 C1[C@H]([C....
18 1TQS - SSO C9 H18 O9 S2 C1[C@H]([C....
19 3CZN - M5G C46 H78 N2 O36 CC(=O)N[C@....
20 2OW6 ic50 = 2 mM NK1 C8 H15 O3 S C1C[C@@H](....
21 3BUP - MAN C6 H12 O6 C([C@@H]1[....
22 3EJT ic50 = 44 nM HN6 C20 H31 N O3 CC(C)(C)c1....
23 3CZS - MAN C6 H12 O6 C([C@@H]1[....
24 3DX1 Ki = 265 uM YHO C5 H11 N O3 C1[C@H]([C....
25 2F7P Ki = 0.249 uM 2SK C13 H19 N O3 S CS[C@@H]1[....
26 3EJP Ki = 2.8 nM HN2 C16 H21 N O4 c1ccc(cc1)....
27 3BVV - WZ3 C19 H34 O15 S CO[C@H]1[C....
28 2F18 ic50 = 80 uM GB1 C13 H20 N2 O3 c1ccc(cc1)....
29 3DX4 Ki = 76 nM GOO C6 H13 N O4 CO[C@@H]1[....
30 2F1A ic50 = 720 uM GB2 C13 H20 N2 O3 c1ccc(cc1)....
31 3D4Y Ki = 2 uM MVL C8 H12 N2 O4 c1cn2c(n1)....
32 3DDF Ki = 67 uM GB6 C13 H18 N2 O4 c1ccc(cc1)....
33 1TQT ic50 ~ 7.5 mM SSD C9 H18 O9 S2 C1[C@H]([C....
34 3DX3 Ki = 300 nM YTB C5 H11 N O4 C1([C@H]([....
35 3BUQ - MAN C6 H12 O6 C([C@@H]1[....
36 3EJR Ki = 2.7 nM HN4 C20 H29 N O4 CC(C)(C)c1....
37 1R34 ic50 = 0.9 mM LKS C14 H20 N2 O4 S [H]/N=C(/C....
38 3BVX - WZ5 C33 H57 N O26 CC(=O)N[C@....
39 1HWW ic50 = 20 nM SWA C8 H15 N O3 C1C[C@H]([....
40 3EJQ Ki = 2.7 nM HN3 C17 H23 N O4 Cc1ccc(cc1....
41 3D50 Ki = 17 uM OEV C15 H29 N O4 CCCCCCCCN[....
42 2F1B ic50 = 1000 uM GB3 C14 H22 N2 O3 C[C@@H]1[C....
43 1R33 ic50 = 0.07 mM LKA C6 H13 N O4 S C([C@@H]1[....
44 1TQW ic50 ~ 7.5 mM BLT C9 H18 O9 S Se C1[C@H]([C....
45 3BVT - WZ1 C13 H24 O10 S CO[C@@H]1[....
46 3BVU - WZ2 C19 H34 O15 S CO[C@@H]1[....
50% Homology Family (46)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2OW7 ic50 = 14 uM NK2 C8 H15 O2 S C1CC[S@@+]....
2 3D51 Ki = 70 uM GOX C6 H12 N2 O5 C([C@@H]1[....
3 3CV5 - M5S C30 H52 O26 C([C@@H]1[....
4 3EJS ic50 = 250 nM HN5 C20 H31 N O3 CC(C)(C)c1....
5 3DX0 Ki = 36 nM MSN C6 H13 N O3 S CS[C@@H]1[....
6 2FYV ic50 = 0.3 mM W72 C11 H21 N O9 C1[C@H]([C....
7 3BVW - WZ4 C33 H57 N O25 S CC(=O)N[C@....
8 3D4Z Ki = 13 uM GIM C8 H13 N2 O4 c1c[n+]2c(....
9 1TQU ic50 ~ 7.5 mM GHA C9 H18 N O9 S C1C([C@@H]....
10 3DDG Ki = 1 uM GB7 C14 H20 N2 O4 CN1[C@@H](....
11 1PS3 Ki = 5.2 mM KIF C8 H12 N2 O6 C([C@@H]1[....
12 3DX2 Ki = 150 nM MZB C6 H13 N O4 S C[S@@](=O)....
13 2F7O Ki = 0.036 uM MSN C6 H13 N O3 S CS[C@@H]1[....
14 3D52 Ki = 520 uM GHR C13 H16 Cl N3 O6 c1cc(ccc1N....
15 1TQV ic50 ~ 7.5 mM SSE C9 H18 O9 S Se C1[C@H]([C....
16 3EJU ic50 = 250 nM HN7 C20 H29 N O4 CC(C)(C)c1....
17 1HXK ic50 = 400 uM DMJ C6 H13 N O4 C1[C@H]([C....
18 1TQS - SSO C9 H18 O9 S2 C1[C@H]([C....
19 3CZN - M5G C46 H78 N2 O36 CC(=O)N[C@....
20 2OW6 ic50 = 2 mM NK1 C8 H15 O3 S C1C[C@@H](....
21 3BUP - MAN C6 H12 O6 C([C@@H]1[....
22 3EJT ic50 = 44 nM HN6 C20 H31 N O3 CC(C)(C)c1....
23 3CZS - MAN C6 H12 O6 C([C@@H]1[....
24 3DX1 Ki = 265 uM YHO C5 H11 N O3 C1[C@H]([C....
25 2F7P Ki = 0.249 uM 2SK C13 H19 N O3 S CS[C@@H]1[....
26 3EJP Ki = 2.8 nM HN2 C16 H21 N O4 c1ccc(cc1)....
27 3BVV - WZ3 C19 H34 O15 S CO[C@H]1[C....
28 2F18 ic50 = 80 uM GB1 C13 H20 N2 O3 c1ccc(cc1)....
29 3DX4 Ki = 76 nM GOO C6 H13 N O4 CO[C@@H]1[....
30 2F1A ic50 = 720 uM GB2 C13 H20 N2 O3 c1ccc(cc1)....
31 3D4Y Ki = 2 uM MVL C8 H12 N2 O4 c1cn2c(n1)....
32 3DDF Ki = 67 uM GB6 C13 H18 N2 O4 c1ccc(cc1)....
33 1TQT ic50 ~ 7.5 mM SSD C9 H18 O9 S2 C1[C@H]([C....
34 3DX3 Ki = 300 nM YTB C5 H11 N O4 C1([C@H]([....
35 3BUQ - MAN C6 H12 O6 C([C@@H]1[....
36 3EJR Ki = 2.7 nM HN4 C20 H29 N O4 CC(C)(C)c1....
37 1R34 ic50 = 0.9 mM LKS C14 H20 N2 O4 S [H]/N=C(/C....
38 3BVX - WZ5 C33 H57 N O26 CC(=O)N[C@....
39 1HWW ic50 = 20 nM SWA C8 H15 N O3 C1C[C@H]([....
40 3EJQ Ki = 2.7 nM HN3 C17 H23 N O4 Cc1ccc(cc1....
41 3D50 Ki = 17 uM OEV C15 H29 N O4 CCCCCCCCN[....
42 2F1B ic50 = 1000 uM GB3 C14 H22 N2 O3 C[C@@H]1[C....
43 1R33 ic50 = 0.07 mM LKA C6 H13 N O4 S C([C@@H]1[....
44 1TQW ic50 ~ 7.5 mM BLT C9 H18 O9 S Se C1[C@H]([C....
45 3BVT - WZ1 C13 H24 O10 S CO[C@@H]1[....
46 3BVU - WZ2 C19 H34 O15 S CO[C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: M5G; Similar ligands found: 152
No: Ligand ECFP6 Tc MDL keys Tc
1 M5G 1 1
2 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.861702 0.9375
3 NAG MAN BMA NDG MAN NAG GAL 0.83 0.979592
4 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.805825 1
5 NAG BMA MAN MAN MAN MAN 0.804348 0.9375
6 NAG MAN GAL BMA NAG MAN NAG GAL 0.78 0.979592
7 NAG MAN GAL BMA NDG MAN NAG GAL 0.78 0.979592
8 MAN BMA NAG NAG MAN NAG GAL GAL 0.78 0.979592
9 NAG MAN MAN MAN NAG GAL NAG GAL 0.78 0.979592
10 NAG NAG BMA MAN MAN 0.773196 1
11 MAN MAN NAG MAN NAG 0.773196 1
12 NAG BMA NAG MAN MAN NAG NAG 0.772277 0.979592
13 WZ5 0.693069 0.938776
14 NAG NAG BMA MAN MAN MAN MAN 0.649123 0.923077
15 NAG GAL NAG 0.642105 1
16 NAG MAN GAL MAN MAN NAG GAL 0.607477 1
17 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.607143 0.865385
18 MAN BMA NAG 0.606383 0.9375
19 GLA GAL NAG 0.606383 0.9375
20 NAG GAL GAL 0.606383 0.9375
21 GAL NAG GAL NAG GAL NAG 0.606061 0.979592
22 NAG GAL GAL NAG 0.606061 1
23 NAG NAG BMA MAN MAN NAG NAG 0.603448 0.90566
24 NAG MAN MAN MAN NAG 0.592233 1
25 WZ4 0.581197 0.884615
26 CBS 0.55914 1
27 NAG GDL 0.55914 1
28 NAG NDG 0.55914 1
29 CBS CBS 0.55914 1
30 NAG MAN BMA 0.554455 0.9375
31 NAG MAN MAN 0.554455 0.9375
32 GAL BGC NAG GAL 0.554455 0.9375
33 ACY 1GN GAL 1GN BGC ACY GAL BGC 0.550459 1
34 1GN ACY GAL ACY 1GN BGC GAL BGC 0.550459 1
35 ASN NAG NAG BMA MAN MAN NAG NAG 0.547619 0.888889
36 NAG GAL BGC 0.544554 0.9375
37 NDG GAL 0.543478 0.9375
38 GAL NDG 0.543478 0.9375
39 NLC 0.543478 0.9375
40 CTO 0.536082 0.979592
41 NAG NAG NAG NAG NDG 0.536082 0.979592
42 NDG NAG NAG 0.536082 0.979592
43 NDG NAG NAG NDG 0.536082 0.979592
44 NAG NAG NAG NAG NAG NAG 0.536082 0.979592
45 NDG NAG NAG NDG NAG 0.536082 0.979592
46 NAG NAG NAG NAG 0.536082 0.979592
47 NDG NAG NAG NAG 0.536082 0.979592
48 NAG NAG NAG NAG NAG NAG NAG NAG 0.536082 0.979592
49 NAG NAG NAG NDG 0.536082 0.979592
50 NAG NAG NAG 0.536082 0.979592
51 NAG NAG NDG 0.536082 0.979592
52 NAG NAG NAG NAG NDG NAG 0.536082 0.979592
53 NAG NAG NAG NAG NAG 0.536082 0.979592
54 NGA GLA GAL BGC 0.533333 0.9375
55 A2G GAL NAG FUC 0.527273 0.979592
56 MAN MAN BMA MAN 0.525773 0.6875
57 MAN MAN MAN MAN 0.525773 0.6875
58 NAG MAN MMA 0.524752 0.938776
59 NAG BMA MAN MAN MAN MAN MAN 0.52381 0.686275
60 GLC GAL NAG GAL 0.52381 0.9375
61 MAN MAN MAN BMA MAN 0.519608 0.6875
62 NAG NAG BMA MAN NAG 0.516949 0.90566
63 MAN MAN MAN BMA MAN MAN MAN 0.513761 0.693878
64 NDG GAL FUC 0.509804 0.958333
65 DR2 0.509804 0.958333
66 FUL GAL NAG 0.509804 0.958333
67 FUC GAL NAG 0.509804 0.958333
68 FUC GAL NDG 0.509804 0.958333
69 MAN BMA MAN MAN MAN 0.50505 0.6875
70 M5S 0.50505 0.6875
71 NAG GAL GAL NAG GAL 0.5 1
72 AML MAN MAN MAN MAN MAN MAN MAN MAN 0.495575 0.62963
73 FUC GAL NAG GAL BGC 0.486957 0.958333
74 MAN NAG GAL 0.485437 0.9375
75 GAL NAG MAN 0.485437 0.9375
76 A2G GAL NAG FUC GAL GLC 0.483607 0.979592
77 GLC GAL NAG GAL FUC A2G 0.483607 0.979592
78 MMA MAN NAG MAN NAG NAG 0.482143 0.96
79 G6S NAG 0.480769 0.725806
80 GAL NAG GAL BGC 0.476636 0.9375
81 BGC GAL NAG GAL 0.476636 0.9375
82 LAT NAG GAL 0.476636 0.9375
83 NGA GAL BGC 0.475728 0.9375
84 MAN MAN NAG 0.471698 0.9
85 KDO MAN MAN MAN MAN MAN 0.468254 0.653846
86 NAG NAG BMA MAN 0.464912 0.923077
87 MAN MMA MAN 0.464646 0.693878
88 NAG NAG NAG NAG NAG NAG NAG 0.464286 0.888889
89 GAL NGA GLA BGC GAL 0.459459 0.9375
90 BGC GAL NAG GAL FUC FUC 0.458333 0.938776
91 GLC GAL NAG GAL FUC FUC 0.458333 0.938776
92 FUC BGC GAL NAG GAL 0.457627 0.958333
93 FUC BGC GAL NAG 0.45614 0.958333
94 BMA NGT MAN MAN 0.452174 0.661017
95 A2G GAL BGC FUC 0.448276 0.958333
96 FUC GAL NAG A2G 0.444444 0.888889
97 MAN NAG 0.444444 0.9375
98 GLA GAL NAG FUC GAL GLC 0.442623 0.958333
99 NDG NAG 0.441176 0.979592
100 TCG 0.440367 0.827586
101 CTO TMX 0.440367 0.827586
102 NAG FUC 0.44 0.916667
103 GLC GLC GLC GLC 0.435644 0.6875
104 GLC GLC GLC BGC 0.432692 0.6875
105 MAN MAN MAN GLC 0.431373 0.6875
106 SN5 SN5 0.431373 0.826923
107 OPM MAN MAN 0.429907 0.618182
108 GAL NAG GAL 0.427273 0.9
109 NGA GAL 0.425743 0.9375
110 NAG GAL 0.425743 0.9375
111 GAL NAG 0.425743 0.9375
112 6PZ BGC GAL 1GN 1GN ACY GAL GAL ACY BGC 0.424658 0.888889
113 NAG MBG 0.421569 0.938776
114 NAG A2G 0.421569 1
115 NAG NGA 0.421569 1
116 WZ3 0.420561 0.68
117 GAL NGA A2G 0.419048 0.979592
118 ACY ACY 6PZ BGC GAL 1GN ACY 1GN GAL GAL ACY BGC 0.417808 0.888889
119 6PZ ACY ACY BGC GAL 1GN 1GN ACY GAL GAL ACY BGC 0.417808 0.888889
120 A2G MBG 0.417476 0.938776
121 MBG A2G 0.417476 0.938776
122 NAG GAL FUC FUC A2G 0.416667 0.979592
123 FUC GAL NAG A2G FUC 0.416667 0.979592
124 3PV 0.415254 0.884615
125 GLC GLC GLC GLC GLC GLC 0.413462 0.6875
126 UNU GAL NAG 0.412281 0.94
127 NAG MUB 0.410714 0.96
128 NAG NAG BMA 0.410714 0.923077
129 NAG NDG BMA 0.410714 0.923077
130 NAG AMU 0.410714 0.96
131 GLA GAL GAL 0.41 0.6875
132 GLA GAL BGC 0.41 0.6875
133 A2G GAL FUC 0.409091 0.958333
134 FUC GLA A2G 0.409091 0.958333
135 FUC GAL A2G 0.409091 0.958333
136 A2G GLA FUC 0.409091 0.958333
137 FUC GL0 A2G 0.409091 0.958333
138 NGA GAL FUC 0.409091 0.958333
139 8VZ 0.405941 0.979592
140 NAG GAL 2NA 0.404762 0.833333
141 NAG NGO 0.40367 0.886792
142 BGC FUC GAL FUC A2G 0.403361 0.938776
143 GLC FUC GAL FUC A2G 0.403361 0.938776
144 BMA BMA GLA BMA BMA 0.401869 0.6875
145 BCW 0.401786 0.938776
146 GAL NAG FUC FUC 0.401786 0.938776
147 BDZ 0.401786 0.938776
148 FUC NDG GAL FUC 0.401786 0.938776
149 FUC NAG GAL FUC 0.401786 0.938776
150 GAL NDG FUC FUC 0.401786 0.938776
151 FUC GAL NDG FUC 0.401786 0.938776
152 FUC GAL NAG FUC 0.401786 0.938776
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3EJR; Ligand: HN4; Similar sites found: 6
This union binding pocket(no: 1) in the query (biounit: 3ejr.bio1) has 34 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3BQF SSM 0.03675 0.40207 2.57732
2 3AJ6 NGA 0.0427 0.40179 2.7972
3 4OWK NGA 0.01797 0.42672 2.89855
4 4CQB MLI 0.02979 0.4143 5.67376
5 5H9O OXM 0.0001484 0.51186 6.30105
6 5D4Y BXP 0.0342 0.41092 14.6479
Feedback