• Home
• Faq
• Browse
• Search
• Download
• Contact Us

Help?

Showing PDB: 3C4H

Navigate

Expand All | Collapse All

Receptor | Ligand | View in 3D

Family: 90% | 70% | 50% | site

External Links

|

Download

      Structure Biounit | Ligand Information

PDB           : .ZIP | .CSV

Family 90% : .ZIP | .CSV

Class         : .ZIP | .CSV

Receptor

PDB id	Resolution	Class	Description	Source	Keywords
3C4H	2.1 Å	EC: 2.4.2.30	HUMAN POLY(ADP-RIBOSE) POLYMERASE 3, CATALYTIC FRAGMENT IN C WITH AN INHIBITOR DR2313	HOMO SAPIENS	ENZYME-INHIBITOR COMPLEX CATALYTIC FRAGMENT STRUCTURAL GENSTRUCTURAL GENOMICS CONSORTIUM SGC GLYCOSYLTRANSFERASE NNUCLEUS TRANSFERASE
Ref.:	STRUCTURAL BASIS FOR INHIBITOR SPECIFICITY IN HUMAN POLY(ADP-RIBOSE) POLYMERASE-3. J.MED.CHEM. V. 52 3108 2009

Ligand

Ligand	Chain:Residue	Validity	Ligand Warnings	Binding Data	NGL Viewer	Molecular Weight (Da)	Formula	SMILES
DMS	A:700;	Invalid;	none;	submit data		78.133	C2 H6 O S	CS(=O...
DRL	A:601;	Valid;	none;	Kd = 2 uM		182.243	C8 H10 N2 O S	CC1=N...

View in 3D viewer

90% Homology Family

Leader

PDB id	Resolution	Class	Description	Source	Keywords
4GV4	1.8 Å	EC: 2.4.2.30	HUMAN ARTD3 (PARP3) - CATALYTIC DOMAIN IN COMPLEX WITH INHIB ME0328	HOMO SAPIENS	NAD ADP-RIBOSE PARP3 ARTD3 ARTD TRANSFERASE DOMAIN ADP-RIBOSYLATION TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX TRANSFERASE ADP-RIBOSYLATION
Ref.:	PARP INHIBITOR WITH SELECTIVITY TOWARD ADP-RIBOSYLTRANSFERASE ARTD3/PARP3 ACS CHEM.BIOL. V. 8 1698 2013

Members (12)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 18 families.
1	3C4H	Kd = 2 uM	DRL	C8 H10 N2 O S	CC1=NC2=C(....
2	4L7P	-	M95	C20 H19 N3 O3	c1ccc(cc1)....
3	4L7L	-	1VA	C20 H21 N3 O3	c1ccc(cc1)....
4	4L7N	-	1VB	C19 H20 N4 O4 S	C[C@@H](c1....
5	4L7R	-	M00	C15 H19 N3 O3	CC[C@@H](C....
6	4L6Z	-	1DC	C18 H18 N4 O2	C[C@@H](c1....
7	3FHB	Kd > 2 uM	GAB	C7 H7 N O2	c1cc(cc(c1....
8	4L70	-	1V9	C20 H21 N3 O2	CC[C@@H](c....
9	4GV4	ic50 = 0.89 uM	MEJ	C19 H19 N3 O2	C[C@@H](c1....
10	4GV0	ic50 = 1.3 uM	8ME	C18 H18 N4 O2	C[C@@H](c1....
11	4L7O	-	1VD	C22 H21 N5 O2	C[C@@H](c1....
12	4GV2	-	5ME	C18 H18 N4 O2	C[C@H](c1c....

70% Homology Family (12)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 14 families.
1	3C4H	Kd = 2 uM	DRL	C8 H10 N2 O S	CC1=NC2=C(....
2	4L7P	-	M95	C20 H19 N3 O3	c1ccc(cc1)....
3	4L7L	-	1VA	C20 H21 N3 O3	c1ccc(cc1)....
4	4L7N	-	1VB	C19 H20 N4 O4 S	C[C@@H](c1....
5	4L7R	-	M00	C15 H19 N3 O3	CC[C@@H](C....
6	4L6Z	-	1DC	C18 H18 N4 O2	C[C@@H](c1....
7	3FHB	Kd > 2 uM	GAB	C7 H7 N O2	c1cc(cc(c1....
8	4L70	-	1V9	C20 H21 N3 O2	CC[C@@H](c....
9	4GV4	ic50 = 0.89 uM	MEJ	C19 H19 N3 O2	C[C@@H](c1....
10	4GV0	ic50 = 1.3 uM	8ME	C18 H18 N4 O2	C[C@@H](c1....
11	4L7O	-	1VD	C22 H21 N5 O2	C[C@@H](c1....
12	4GV2	-	5ME	C18 H18 N4 O2	C[C@H](c1c....

50% Homology Family (46)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 9 families.
1	5XSU	Kd = 180 nM	8E3	C15 H13 F N4 O2	c1c(cc2c(c....
2	4R6E	ic50 = 132 nM	3JD	C19 H20 N4 O	c1cc2cn(nc....
3	4ZZZ	Kd = 0.087 uM	FSU	C13 H16 N2 O3	COCCCN1Cc2....
4	5XSR	Kd = 0.000000064 M	8EC	C15 H13 F N4 O S	c1c(cc2c(c....
5	6VKK	-	RPB	C19 H18 F N3 O	CNCc1ccc(c....
6	3GJW	Ki = 0.005 uM	GJW	C16 H17 N3 O	c1cc2n(c1)....
7	4L6S	Kd = 0.003 uM	1WQ	C21 H21 Cl N2 O2	C[C@H]1C(=....
8	4HHY	ic50 = 1.92 nM	15R	C33 H30 F N5 O4	c1ccc2c(c1....
9	4UND	-	2YQ	C19 H14 F2 N6 O	Cn1c(ncn1)....
10	5XST	ic50 = 27 nM	8E6	C15 H13 F N4 O S	c1c(cc2c(c....
11	3L3L	Ki = 33 nM	L3L	C14 H17 N3 O2	c1cc2c(c(c....
12	4PJT	ic50 = 0.57 nM	2YQ	C19 H14 F2 N6 O	Cn1c(ncn1)....
13	3L3M	Ki = 0.006 uM	A92	C19 H19 F N4 O	c1cc(c2c(c....
14	6XVW	-	O3H	C19 H21 N5 O S	c1ccc2c(c1....
15	4TVJ	ic50 = 251 nM	09L	C24 H23 F N4 O3	c1ccc2c(c1....
16	4ZZY	Kd = 1.389 uM	D7N	C20 H24 F3 N3 O2	c1c(cc(c2c....
17	4PJV	-	2YQ	C19 H14 F2 N6 O	Cn1c(ncn1)....
18	3KCZ	-	3AB	C7 H8 N2 O	c1cc(cc(c1....
19	3KJD	Kd = 2.9 nM	78P	C13 H16 N4 O	C[C@@]1(CC....
20	4ZZX	Kd = 0.125 uM	FSU	C13 H16 N2 O3	COCCCN1Cc2....
21	3C4H	Kd = 2 uM	DRL	C8 H10 N2 O S	CC1=NC2=C(....
22	4L7P	-	M95	C20 H19 N3 O3	c1ccc(cc1)....
23	4L7L	-	1VA	C20 H21 N3 O3	c1ccc(cc1)....
24	4L7N	-	1VB	C19 H20 N4 O4 S	C[C@@H](c1....
25	4L7R	-	M00	C15 H19 N3 O3	CC[C@@H](C....
26	4L6Z	-	1DC	C18 H18 N4 O2	C[C@@H](c1....
27	3FHB	Kd > 2 uM	GAB	C7 H7 N O2	c1cc(cc(c1....
28	4L70	-	1V9	C20 H21 N3 O2	CC[C@@H](c....
29	4GV4	ic50 = 0.89 uM	MEJ	C19 H19 N3 O2	C[C@@H](c1....
30	4GV0	ic50 = 1.3 uM	8ME	C18 H18 N4 O2	C[C@@H](c1....
31	4L7O	-	1VD	C22 H21 N5 O2	C[C@@H](c1....
32	4GV2	-	5ME	C18 H18 N4 O2	C[C@H](c1c....
33	6NRG	ic50 = 56 nM	KYY	C17 H12 F N5 O3	c1cc2c(c(o....
34	6NRJ	ic50 = 36 nM	KYJ	C26 H20 N4 O4	c1ccc2c(c1....
35	6NRI	ic50 = 27 nM	KYM	C25 H21 N5 O4	c1cc2c(c(c....
36	6NTU	-	GLC FRU	n/a	n/a
37	6NRF	ic50 = 18 nM	KYV	C28 H25 N5 O4	c1ccc2c(c1....
38	6NRH	ic50 = 55 nM	KYP	C25 H23 N5 O4	c1cc2c(c(o....
39	6BHV	Kd = 5.87 uM	DQV	C22 H28 N6 O14 P2	c1cc(cc(c1....
40	2PAX	ic50 = 0.18 uM	4AN	C12 H8 N2 O2	c1cc2c(ccc....
41	3PAX	ic50 = 10 uM	3MB	C8 H9 N O2	COc1cccc(c....
42	1EFY	Ki = 6 nM	BZC	C15 H13 N3 O2	COc1cccc(c....
43	1PAX	-	DHQ	C10 H11 N O	Cc1cccc2c1....
44	6I8T	-	H7Z	C21 H29 N3 O2	C[C@@H]1c2....
45	6I8M	-	H7W	C21 H29 N3 O2	C[C@H]1c2c....
46	1A26	-	CNA	C22 H30 N7 O13 P2	c1cc(c[n+]....

Polypharmacology

Similar Ligands (2D)

Ligand no: 1; Ligand: DRL; Similar ligands found: 1

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	DRL	1	1

Similar Ligands (3D)

Ligand no: 1; Ligand: DRL; Similar ligands found: 1070

No:	Ligand	Similarity coefficient
1	M1Q	1.0000
2	AQO	0.9818
3	MEW	0.9811
4	PE0	0.9807
5	4HC	0.9805
6	M6N	0.9801
7	Q24	0.9783
8	AJ2	0.9781
9	J9W	0.9775
10	M5K	0.9774
11	BGC	0.9742
12	MO8	0.9728
13	AZ8	0.9715
14	QBK	0.9679
15	B62	0.9674
16	GLC	0.9658
17	24W	0.9651
18	XHP	0.9643
19	MAQ	0.9639
20	QX4	0.9634
21	44W	0.9634
22	URC	0.9634
23	6VD	0.9620
24	DQU	0.9611
25	44V	0.9595
26	AZA	0.9594
27	HQD	0.9592
28	0FO	0.9586
29	7VS	0.9585
30	B60	0.9579
31	OTW	0.9570
32	1SQ	0.9565
33	4MU	0.9563
34	9MG	0.9549
35	FOT	0.9542
36	ES1	0.9541
37	9DG	0.9535
38	H42	0.9533
39	B55	0.9532
40	1LQ	0.9532
41	6ME	0.9530
42	HLZ	0.9528
43	0N7	0.9524
44	GUN	0.9522
45	8TX	0.9521
46	UNC	0.9519
47	5JQ	0.9518
48	MVN	0.9515
49	XAZ	0.9515
50	XAN	0.9513
51	VK3	0.9512
52	7ME	0.9508
53	4YS	0.9508
54	M2K	0.9507
55	COU	0.9495
56	75K	0.9494
57	C2U	0.9493
58	0W8	0.9493
59	GCS	0.9492
60	MUA	0.9491
61	RXA	0.9489
62	OCH	0.9488
63	2AK	0.9486
64	1NP	0.9484
65	IGA	0.9483
66	NQ	0.9482
67	AZ9	0.9475
68	ORO	0.9472
69	5SG	0.9471
70	BTY	0.9470
71	5JL	0.9469
72	2AQ	0.9469
73	7HQ	0.9468
74	03V	0.9465
75	JBH	0.9464
76	YH7	0.9458
77	6AP	0.9457
78	B53	0.9456
79	5Q0	0.9453
80	1XM	0.9453
81	0P6	0.9453
82	JBQ	0.9452
83	4FS	0.9451
84	HQY	0.9448
85	G3F	0.9447
86	B57	0.9446
87	BOA	0.9445
88	JPZ	0.9444
89	I3A	0.9443
90	ES5	0.9442
91	141	0.9442
92	DX4	0.9441
93	OXC	0.9438
94	IJZ	0.9434
95	5IQ	0.9432
96	1LM	0.9431
97	3F0	0.9430
98	KT7	0.9428
99	BCP	0.9427
100	FDB	0.9424
101	DBH	0.9422
102	O72	0.9418
103	AZG	0.9417
104	CFP	0.9417
105	A2F	0.9414
106	1XN	0.9410
107	290	0.9407
108	3HA	0.9406
109	3M0	0.9404
110	N5J	0.9403
111	HJP	0.9402
112	ISN	0.9401
113	Q6T	0.9399
114	CLZ	0.9398
115	6GU	0.9396
116	FE DB1	0.9388
117	3WA	0.9388
118	HH8	0.9386
119	3MG	0.9386
120	8IG	0.9385
121	7W4	0.9384
122	GAL	0.9384
123	7ZE	0.9383
124	4ME	0.9382
125	DHQ	0.9380
126	DIU	0.9377
127	NOJ	0.9371
128	3IT	0.9370
129	HH5	0.9370
130	2D0	0.9368
131	KKN	0.9365
132	KIB	0.9364
133	AKH	0.9360
134	XQ0	0.9358
135	5WV	0.9358
136	5RG	0.9357
137	M1H	0.9356
138	LZM	0.9355
139	54G	0.9352
140	RM1	0.9352
141	KUF	0.9351
142	ICO	0.9350
143	2ZQ	0.9348
144	DBJ	0.9346
145	5M0	0.9345
146	ES7	0.9345
147	5WY	0.9345
148	GTQ	0.9344
149	6CS	0.9344
150	1DW	0.9343
151	8CM	0.9342
152	42A	0.9339
153	5QY	0.9339
154	12B	0.9337
155	32X	0.9335
156	8S0	0.9334
157	N2I	0.9332
158	JAE	0.9330
159	EA1	0.9330
160	7VJ	0.9325
161	5MK	0.9324
162	7B4	0.9323
163	NMJ	0.9322
164	BZX	0.9322
165	SX1	0.9321
166	SKA	0.9321
167	42C	0.9320
168	SE2	0.9319
169	D07	0.9317
170	TTL	0.9317
171	TOF	0.9316
172	9TZ	0.9314
173	A7W	0.9313
174	KJU	0.9313
175	92K	0.9312
176	CWS	0.9312
177	G6D	0.9312
178	34D	0.9311
179	3DM	0.9311
180	G5V	0.9307
181	PXL	0.9307
182	AW5	0.9306
183	BZ3	0.9304
184	KJY	0.9303
185	8WO	0.9302
186	CTS	0.9301
187	G3E	0.9300
188	1P7	0.9300
189	0CU	0.9300
190	2HQ	0.9298
191	UAN	0.9298
192	3NT	0.9298
193	5RN	0.9298
194	6M9	0.9297
195	AHR	0.9294
196	3PF	0.9293
197	3HB	0.9293
198	4XH	0.9292
199	NID	0.9290
200	7NI	0.9290
201	5OB	0.9290
202	J5I	0.9288
203	680	0.9284
204	NDM	0.9283
205	BTE	0.9283
206	VNL	0.9283
207	F05	0.9282
208	DPZ	0.9281
209	FA0	0.9279
210	OVV	0.9278
211	INE	0.9278
212	PYQ	0.9276
213	DIN	0.9273
214	E7Z	0.9273
215	7W1	0.9272
216	0RW	0.9272
217	6M4	0.9272
218	GDE	0.9271
219	XYP	0.9270
220	5QX	0.9269
221	D48	0.9266
222	2FQ	0.9266
223	BK9	0.9263
224	GAB	0.9263
225	4CS	0.9263
226	495	0.9260
227	SHG	0.9260
228	SVN	0.9259
229	12Q	0.9258
230	KJH	0.9257
231	QPR	0.9254
232	PRF	0.9253
233	2CK	0.9252
234	TH7	0.9252
235	15L	0.9251
236	MRW	0.9251
237	DOR	0.9251
238	Q88	0.9251
239	APZ	0.9249
240	3AB	0.9248
241	8GC	0.9248
242	DOB	0.9244
243	ADZ	0.9243
244	25W	0.9243
245	M0W	0.9241
246	HHA	0.9240
247	BHA	0.9240
248	WCE	0.9240
249	MT0	0.9240
250	4M0	0.9239
251	9EW	0.9239
252	3BZ	0.9239
253	4JQ	0.9239
254	HQT	0.9239
255	T6C	0.9238
256	N8Y	0.9237
257	ZZT	0.9236
258	CTL	0.9236
259	LGC	0.9235
260	3ID	0.9232
261	AJV	0.9232
262	HPA	0.9232
263	MQN	0.9231
264	SWD	0.9231
265	9KT	0.9230
266	5B1	0.9230
267	FYU	0.9230
268	86J	0.9229
269	HMH	0.9229
270	S76	0.9226
271	TWO	0.9224
272	SAL	0.9224
273	9R5	0.9224
274	PFB	0.9223
275	BDP	0.9223
276	5HN	0.9222
277	FBB	0.9221
278	5NU	0.9217
279	K2T	0.9216
280	ES0	0.9215
281	BEA	0.9215
282	CWM	0.9214
283	LKA	0.9213
284	4JT	0.9212
285	2AL	0.9212
286	23A	0.9211
287	BRT	0.9211
288	FBG	0.9211
289	3MB	0.9207
290	ES2	0.9205
291	82I	0.9205
292	5H1	0.9204
293	6AI	0.9203
294	F60	0.9203
295	4Z4	0.9203
296	5WX	0.9203
297	R8V	0.9202
298	0JD	0.9202
299	2EC	0.9202
300	14O	0.9201
301	SWA	0.9201
302	BHO	0.9200
303	5MI	0.9199
304	0TU	0.9198
305	4AA	0.9197
306	KDV	0.9197
307	LI6	0.9197
308	FDR	0.9197
309	4YO	0.9196
310	MS9	0.9195
311	8ZE	0.9194
312	OVM	0.9194
313	4TU	0.9193
314	Q7A	0.9192
315	IV2	0.9191
316	7B3	0.9188
317	UEG	0.9188
318	TTY	0.9188
319	5CU	0.9187
320	ZZ3	0.9186
321	LSA	0.9185
322	SKM	0.9183
323	PQ0	0.9182
324	OA3	0.9181
325	5XC	0.9179
326	PDC	0.9179
327	5WU	0.9178
328	2FY	0.9178
329	M1A	0.9177
330	D1X	0.9176
331	HZQ	0.9175
332	24B	0.9175
333	PXM	0.9173
334	MR1	0.9173
335	KIA	0.9172
336	M0Q	0.9172
337	5MB	0.9171
338	2A7	0.9170
339	JFD	0.9170
340	B5D	0.9170
341	1PT	0.9170
342	OW4	0.9169
343	DIE	0.9169
344	11S	0.9167
345	7MH	0.9166
346	2K4	0.9165
347	FBU	0.9165
348	PRZ	0.9165
349	F5B	0.9163
350	PH2	0.9163
351	1P8	0.9162
352	BE2	0.9162
353	36R	0.9161
354	TGX	0.9161
355	TT4	0.9160
356	1F1	0.9160
357	LXC	0.9160
358	3DO	0.9156
359	ES9	0.9155
360	KBG	0.9155
361	Q71	0.9155
362	3Z8	0.9153
363	CFF	0.9153
364	NPY	0.9152
365	53C	0.9152
366	7WR	0.9151
367	ODO	0.9151
368	TEP	0.9149
369	ROI	0.9149
370	8H8	0.9149
371	G1O	0.9147
372	SYV	0.9147
373	XQG	0.9147
374	ZVO	0.9145
375	97T	0.9144
376	CLW	0.9143
377	PEY	0.9140
378	NDH	0.9140
379	Z5P	0.9140
380	JUG	0.9139
381	4SV	0.9138
382	GYE	0.9138
383	HHR	0.9137
384	EQT	0.9135
385	5GU	0.9135
386	ET2	0.9134
387	20J	0.9134
388	FLV	0.9134
389	DBX	0.9134
390	QUZ	0.9132
391	5NE	0.9132
392	67N	0.9130
393	KYA	0.9130
394	BCU	0.9128
395	F12	0.9127
396	LDR	0.9126
397	H4N	0.9125
398	GXY	0.9123
399	EV0	0.9121
400	HMU	0.9121
401	EXO	0.9120
402	FK1	0.9119
403	DX3	0.9119
404	DMD	0.9116
405	6M1	0.9116
406	ADE	0.9113
407	JIF	0.9113
408	VOH	0.9111
409	NTZ	0.9111
410	3U4	0.9110
411	ZZ8	0.9110
412	SXS	0.9109
413	V55	0.9109
414	VGD	0.9108
415	2H5	0.9108
416	6NT	0.9107
417	XXR	0.9106
418	5VM	0.9104
419	H33	0.9104
420	DHK	0.9104
421	94W	0.9103
422	5RO	0.9103
423	MWP	0.9101
424	X05	0.9101
425	2F6	0.9099
426	4KL	0.9098
427	ZZZ	0.9098
428	JBK	0.9097
429	GRE	0.9096
430	9AP	0.9094
431	6F0	0.9093
432	X09	0.9092
433	0XT	0.9091
434	ZWZ	0.9090
435	ASO	0.9090
436	7WA	0.9090
437	BMA	0.9089
438	39A	0.9088
439	AS3	0.9087
440	6LW	0.9086
441	1WG	0.9086
442	6MP	0.9085
443	FRU	0.9084
444	10L	0.9083
445	PD2	0.9083
446	OVP	0.9081
447	7HP	0.9079
448	GIO	0.9079
449	5NI	0.9077
450	HLD	0.9076
451	B2J	0.9074
452	226	0.9071
453	ES6	0.9071
454	ABV	0.9071
455	BP1	0.9071
456	209	0.9070
457	DNC	0.9070
458	JKE	0.9069
459	37T	0.9069
460	2BG	0.9066
461	2ZV	0.9065
462	P9P	0.9065
463	329	0.9063
464	8WT	0.9062
465	ALL	0.9061
466	9FL	0.9059
467	8OZ	0.9059
468	DHB	0.9058
469	8XQ	0.9057
470	M5N	0.9057
471	TFU	0.9057
472	F0J	0.9055
473	PX7	0.9054
474	0FK	0.9053
475	GCU	0.9053
476	A13	0.9052
477	3NY	0.9051
478	9DA	0.9049
479	2ZM	0.9048
480	9HX	0.9047
481	7MU	0.9046
482	3RK	0.9046
483	1WD	0.9045
484	7WV	0.9043
485	DNF	0.9043
486	CWJ	0.9042
487	QSH	0.9042
488	YQA	0.9042
489	MBG	0.9042
490	F81	0.9039
491	3Z7	0.9039
492	ISE	0.9039
493	SYA	0.9038
494	SOE	0.9038
495	MJ2	0.9037
496	0HN	0.9037
497	J9Q	0.9035
498	QX2	0.9034
499	GJS	0.9033
500	JB5	0.9031
501	35C	0.9030
502	NSP	0.9030
503	X8D	0.9029
504	TBP	0.9028
505	F31	0.9028
506	1KP	0.9027
507	EJZ	0.9027
508	NTM	0.9027
509	C2Y	0.9026
510	A29	0.9025
511	9ZE	0.9025
512	2A9	0.9025
513	INO	0.9025
514	149	0.9025
515	GZ8	0.9023
516	GZL	0.9023
517	HNQ	0.9022
518	QAS	0.9022
519	TSS	0.9022
520	XCZ	0.9021
521	GV9	0.9021
522	M1E	0.9021
523	2CQ	0.9020
524	PQK	0.9020
525	I6G	0.9019
526	8NY	0.9018
527	GM7	0.9018
528	MYJ	0.9017
529	WOO	0.9017
530	XIY	0.9017
531	173	0.9016
532	JG8	0.9016
533	2KA	0.9016
534	0GZ	0.9016
535	GOX	0.9015
536	52C	0.9015
537	150	0.9014
538	BPU	0.9014
539	II6	0.9014
540	3R6	0.9013
541	3XX	0.9013
542	GCB	0.9012
543	LT2	0.9012
544	PHT	0.9012
545	0HO	0.9011
546	4ZC	0.9011
547	EVA	0.9011
548	6NI	0.9010
549	1IT	0.9009
550	HLR	0.9008
551	ASC	0.9008
552	F9Y	0.9008
553	QSB	0.9006
554	G12	0.9005
555	F4Z	0.9004
556	HIS	0.9004
557	NGT	0.9003
558	IFL	0.9002
559	ADK	0.9001
560	FGZ	0.9000
561	KLW	0.8999
562	SRO	0.8999
563	9CA	0.8996
564	SHA	0.8996
565	FUL	0.8996
566	4NC	0.8994
567	ES4	0.8994
568	YSO	0.8993
569	G2F	0.8993
570	2LY	0.8990
571	3FH	0.8990
572	92P	0.8989
573	4HM	0.8987
574	HKD	0.8987
575	AJY	0.8986
576	0F9	0.8986
577	MVL	0.8986
578	PM6	0.8985
579	15E	0.8984
580	2HO	0.8983
581	GLA	0.8983
582	2FG	0.8983
583	NOY	0.8982
584	6OT	0.8981
585	3A9	0.8980
586	GTL	0.8979
587	45C	0.8979
588	JTH	0.8979
589	TC7	0.8978
590	4M4	0.8978
591	93K	0.8976
592	23J	0.8975
593	RAM	0.8974
594	QWW	0.8973
595	FBM	0.8973
596	FP1	0.8973
597	1X7	0.8973
598	1U6	0.8973
599	FUF	0.8970
600	3MA	0.8968
601	QAT	0.8968
602	PHH	0.8967
603	7MX	0.8967
604	SOR	0.8967
605	069	0.8966
606	MZB	0.8965
607	HA7	0.8963
608	12M	0.8962
609	W81	0.8961
610	K17	0.8960
611	RM4	0.8957
612	INS	0.8956
613	8G0	0.8954
614	6BL	0.8953
615	06B	0.8952
616	R8S	0.8950
617	GOG	0.8948
618	LCN	0.8948
619	JXW	0.8947
620	TBS	0.8944
621	ABI	0.8944
622	XYS	0.8944
623	ZYR	0.8943
624	DNA	0.8943
625	AEZ	0.8943
626	2HU	0.8942
627	AX3	0.8942
628	JND	0.8942
629	6RQ	0.8941
630	39O	0.8940
631	A65	0.8940
632	DFB	0.8940
633	1GN	0.8939
634	NNO	0.8938
635	8HC	0.8938
636	15N	0.8937
637	Q77	0.8937
638	3HM	0.8934
639	EUG	0.8932
640	PHE	0.8931
641	BZJ	0.8930
642	FHB	0.8928
643	9TW	0.8928
644	FBW	0.8928
645	4XV	0.8928
646	EYK	0.8925
647	XX2	0.8925
648	PFL	0.8925
649	M4E	0.8924
650	CHB	0.8924
651	XM0	0.8923
652	HX3	0.8922
653	HXX	0.8922
654	X0W	0.8922
655	JA8	0.8921
656	1M2	0.8921
657	GIV	0.8921
658	30G	0.8921
659	GTR	0.8920
660	H5B	0.8918
661	261	0.8917
662	4A3	0.8916
663	IHB	0.8916
664	8GK	0.8916
665	E1T	0.8913
666	0FN	0.8912
667	5NS	0.8911
668	LYL	0.8910
669	5CL	0.8906
670	8XL	0.8905
671	OTD	0.8905
672	JAW	0.8903
673	LNR	0.8903
674	NVU	0.8903
675	OMD	0.8903
676	1P3	0.8903
677	XBZ	0.8901
678	L3Q	0.8901
679	MFB	0.8900
680	3QV	0.8899
681	HTP	0.8899
682	AX7	0.8898
683	LDP	0.8898
684	JU2	0.8897
685	GIM	0.8897
686	FCB	0.8897
687	5MH	0.8895
688	GLT	0.8894
689	UFO	0.8894
690	R9Y	0.8893
691	51R	0.8890
692	FBT	0.8890
693	PZI	0.8888
694	PYD	0.8886
695	LFR	0.8886
696	TLD	0.8885
697	K32	0.8884
698	DQN	0.8884
699	BSX	0.8883
700	CFI	0.8883
701	K22	0.8882
702	GCW	0.8882
703	NIZ	0.8881
704	GJP	0.8880
705	270	0.8880
706	RNS	0.8880
707	4RU	0.8878
708	HQJ	0.8878
709	RMN	0.8878
710	CKA	0.8877
711	MHK	0.8875
712	ANN	0.8875
713	SLS	0.8874
714	RD4	0.8874
715	QOS	0.8872
716	4XS	0.8872
717	FSW	0.8872
718	AIN	0.8870
719	MT5	0.8869
720	TH0	0.8868
721	J9T	0.8867
722	2MP	0.8865
723	JDN	0.8864
724	IDM	0.8864
725	PA1	0.8861
726	8W9	0.8861
727	NLA	0.8861
728	ARB	0.8861
729	1HN	0.8860
730	JZ3	0.8860
731	34A	0.8859
732	CH9	0.8857
733	4ZE	0.8856
734	DA4	0.8855
735	4VS	0.8854
736	3OC	0.8854
737	275	0.8852
738	HT4	0.8851
739	JXN	0.8851
740	X6X	0.8849
741	0R0	0.8846
742	NAG	0.8846
743	BNT	0.8845
744	HA5	0.8845
745	MAN	0.8845
746	GBD	0.8844
747	NPO	0.8843
748	RPQ	0.8843
749	2MI	0.8842
750	KOJ	0.8841
751	4SX	0.8841
752	2YU	0.8840
753	43M	0.8839
754	FUC	0.8836
755	AA	0.8836
756	MWM	0.8836
757	091	0.8836
758	BSP	0.8835
759	948	0.8835
760	IPB	0.8835
761	YIO	0.8835
762	XYD	0.8833
763	URF	0.8833
764	JKZ	0.8831
765	CN0	0.8830
766	PHB	0.8829
767	HBD	0.8829
768	ISZ	0.8827
769	GTZ	0.8826
770	APG	0.8826
771	2AC	0.8825
772	RB5	0.8824
773	OW7	0.8824
774	P92	0.8822
775	NK	0.8821
776	FBV	0.8821
777	TDR	0.8821
778	I1N	0.8821
779	3AL	0.8820
780	AFR	0.8820
781	VNJ	0.8820
782	UFV	0.8820
783	DEN	0.8819
784	MCT	0.8817
785	KYD	0.8816
786	5JC	0.8815
787	A1U	0.8815
788	F3B	0.8815
789	NDG	0.8814
790	BEZ	0.8812
791	IPZ	0.8811
792	WBU	0.8810
793	PNZ	0.8810
794	4P5	0.8810
795	4JO	0.8808
796	THA	0.8808
797	BEN	0.8807
798	4XR	0.8807
799	0MK	0.8807
800	BCF	0.8806
801	0W1	0.8805
802	IFM	0.8805
803	1AL	0.8804
804	NSG	0.8803
805	IBF	0.8803
806	3SK	0.8802
807	JZ2	0.8799
808	QWN	0.8799
809	J6W	0.8799
810	FB1	0.8799
811	4JJ	0.8798
812	TM7	0.8798
813	MNM	0.8798
814	O2A	0.8797
815	ONR	0.8797
816	TXW	0.8796
817	293	0.8796
818	49O	0.8796
819	ICP	0.8794
820	TIY	0.8794
821	X0V	0.8794
822	HFB	0.8793
823	67X	0.8791
824	286	0.8789
825	ANF	0.8789
826	BBF	0.8789
827	QXW	0.8788
828	4HO	0.8788
829	NCA	0.8788
830	4CL	0.8787
831	GAG	0.8787
832	DHR	0.8786
833	NCD	0.8783
834	ARP	0.8782
835	8NX	0.8781
836	EKZ	0.8781
837	ESI	0.8781
838	JBE	0.8780
839	E35	0.8779
840	5UC	0.8778
841	6TZ	0.8778
842	OXQ	0.8775
843	PBC	0.8775
844	PJW	0.8775
845	NCT	0.8773
846	IUR	0.8771
847	39U	0.8771
848	NIO	0.8771
849	FUD	0.8771
850	IFP	0.8769
851	IAC	0.8769
852	PAB	0.8767
853	MWJ	0.8766
854	1A7	0.8766
855	6KT	0.8766
856	APS	0.8766
857	L5V	0.8765
858	HBA	0.8765
859	GIF	0.8765
860	LZ2	0.8764
861	1MC	0.8764
862	0LH	0.8764
863	JR2	0.8764
864	BAM	0.8763
865	NGO	0.8761
866	E5X	0.8761
867	AX2	0.8760
868	VXX	0.8760
869	BDF	0.8759
870	SF9	0.8759
871	MZG	0.8758
872	DRG	0.8757
873	DGJ	0.8757
874	1Y6	0.8755
875	6UA	0.8755
876	GAF	0.8755
877	2MN	0.8754
878	2LP	0.8753
879	PCI	0.8753
880	Y8I	0.8751
881	C2A	0.8751
882	AZF	0.8751
883	60P	0.8750
884	SFU	0.8750
885	BR9	0.8749
886	GXL	0.8749
887	EOL	0.8748
888	27Y	0.8746
889	P3K	0.8746
890	UNU	0.8745
891	BR8	0.8745
892	6PC	0.8744
893	SS1	0.8744
894	DEE	0.8743
895	260	0.8742
896	3BU	0.8742
897	60Q	0.8741
898	EN1	0.8741
899	DMJ	0.8740
900	5VJ	0.8740
901	8MO	0.8740
902	2K8	0.8738
903	TSR	0.8737
904	OXZ	0.8735
905	TAG	0.8735
906	F69	0.8734
907	B56	0.8732
908	9RW	0.8731
909	9FE	0.8730
910	RUY	0.8730
911	VGL	0.8728
912	PZA	0.8727
913	BZI	0.8727
914	826	0.8726
915	GVH	0.8725
916	FDK	0.8725
917	FAN	0.8724
918	GOO	0.8722
919	IND	0.8721
920	P84	0.8720
921	FCA	0.8720
922	HC4	0.8720
923	3J8	0.8719
924	NTN	0.8718
925	28N	0.8716
926	LT8	0.8716
927	TYL	0.8716
928	AH8	0.8715
929	PBZ	0.8715
930	BZF	0.8715
931	717	0.8715
932	344	0.8714
933	SJ5	0.8713
934	27B	0.8712
935	YRL	0.8711
936	GT0	0.8710
937	7CZ	0.8710
938	MT8	0.8710
939	13X	0.8709
940	0TR	0.8709
941	J9N	0.8709
942	AMG	0.8709
943	K8X	0.8708
944	M2H	0.8708
945	5ZE	0.8708
946	K6X	0.8708
947	SF6	0.8708
948	4MA	0.8707
949	EMZ	0.8706
950	M6Z	0.8705
951	NBZ	0.8705
952	174	0.8705
953	AC6	0.8704
954	0R1	0.8703
955	IDH	0.8703
956	4JP	0.8701
957	DK1	0.8699
958	MPI	0.8699
959	2JK	0.8698
960	2GS	0.8698
961	GCV	0.8697
962	AEF	0.8695
963	3CE	0.8693
964	M1Z	0.8692
965	G4D	0.8691
966	H7Y	0.8690
967	WDL	0.8690
968	AGK	0.8690
969	2ZX	0.8689
970	4VY	0.8689
971	PYG	0.8688
972	HHS	0.8685
973	6MH	0.8684
974	ADA	0.8683
975	LZ1	0.8683
976	R8A	0.8680
977	4P0	0.8680
978	FH2	0.8679
979	18N	0.8679
980	6XI	0.8677
981	4AN	0.8676
982	CFA	0.8676
983	0CT	0.8675
984	ARA	0.8675
985	NK2	0.8674
986	Z82	0.8673
987	RIP	0.8671
988	DUB	0.8670
989	K5W	0.8669
990	QSC	0.8669
991	UQ	0.8666
992	3AY	0.8666
993	C9E	0.8664
994	4FH	0.8664
995	LRH	0.8664
996	F9P	0.8662
997	PAC	0.8662
998	MBD	0.8660
999	F1A	0.8660
1000	FLM	0.8660
1001	ESP	0.8660
1002	PBA	0.8660
1003	HHT	0.8660
1004	ERH	0.8659
1005	GMN	0.8658
1006	AY4	0.8653
1007	IF7	0.8652
1008	RIB	0.8651
1009	GNM	0.8651
1010	IWT	0.8651
1011	M3S	0.8650
1012	F2W	0.8649
1013	J01	0.8649
1014	3GQ	0.8648
1015	JFJ	0.8648
1016	PKU	0.8647
1017	BZ2	0.8647
1018	SMN	0.8646
1019	NGA	0.8644
1020	14J	0.8642
1021	47J	0.8642
1022	MIG	0.8641
1023	2MY	0.8639
1024	6R8	0.8639
1025	MSN	0.8638
1026	4VP	0.8637
1027	TCZ	0.8635
1028	2CM	0.8635
1029	DFU	0.8634
1030	3MC	0.8630
1031	2C9	0.8630
1032	9PY	0.8630
1033	94N	0.8628
1034	7D2	0.8627
1035	GSY	0.8625
1036	SRT	0.8621
1037	JZ9	0.8620
1038	MAJ	0.8620
1039	3FA	0.8620
1040	3MH	0.8620
1041	N8P	0.8618
1042	MMA	0.8615
1043	FFP	0.8610
1044	GLY PRO	0.8609
1045	4JM	0.8608
1046	SKF	0.8598
1047	4WL	0.8598
1048	PHU	0.8594
1049	ESX	0.8588
1050	1QP	0.8584
1051	E7S	0.8584
1052	H76	0.8580
1053	61M	0.8578
1054	64C	0.8576
1055	QQQ	0.8576
1056	AC0	0.8570
1057	JYB	0.8569
1058	SR1	0.8568
1059	9LI	0.8567
1060	R20	0.8564
1061	SVD	0.8564
1062	PBR	0.8560
1063	PRY	0.8560
1064	AP4	0.8553
1065	7I2	0.8551
1066	4ZA	0.8549
1067	K37	0.8544
1068	KGK	0.8522
1069	P72	0.8519
1070	KLK	0.8518

Similar Binding Sites (Proteins are less than 50% similar to leader)

Pocket No.: 1; Query (leader) PDB : 4GV4; Ligand: MEJ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 1) in the query (biounit: 4gv4.bio1) has 20 residues
No:	Leader PDB	Ligand	Sequence Similarity

APoc FAQ