Receptor
PDB id Resolution Class Description Source Keywords
3AB4 2.47 Å EC: 2.7.2.4 CRYSTAL STRUCTURE OF FEEDBACK INHIBITION RESISTANT MUTANT OF KINASE FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH LYSIT HREONINE CORYNEBACTERIUM GLUTAMICUM ASPARTATE KINASE CONCERTED INHIBITION ALTERNATIVE INITIATIAMINO-ACID BIOSYNTHESIS ATP-BINDING DIAMINOPIMELATE BIOSYKINASE LYSINE BIOSYNTHESIS NUCLEOTIDE-BINDING TRANSFERAS
Ref.: MECHANISM OF CONCERTED INHIBITION OF {ALPHA}2{BETA} HETEROOLIGOMERIC ASPARTATE KINASE FROM CORYNEBACTER GLUTAMICUM J.BIOL.CHEM. V. 285 27477 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LYS A:601;
C:601;
E:601;
G:601;
K:601;
M:601;
O:601;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
submit data
147.195 C6 H15 N2 O2 C(CC[...
THR A:501;
B:201;
C:501;
D:201;
E:501;
F:201;
G:501;
H:201;
I:501;
J:201;
K:501;
L:201;
M:501;
N:201;
O:501;
P:201;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
119.119 C4 H9 N O3 C[C@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3AB4 2.47 Å EC: 2.7.2.4 CRYSTAL STRUCTURE OF FEEDBACK INHIBITION RESISTANT MUTANT OF KINASE FROM CORYNEBACTERIUM GLUTAMICUM IN COMPLEX WITH LYSIT HREONINE CORYNEBACTERIUM GLUTAMICUM ASPARTATE KINASE CONCERTED INHIBITION ALTERNATIVE INITIATIAMINO-ACID BIOSYNTHESIS ATP-BINDING DIAMINOPIMELATE BIOSYKINASE LYSINE BIOSYNTHESIS NUCLEOTIDE-BINDING TRANSFERAS
Ref.: MECHANISM OF CONCERTED INHIBITION OF {ALPHA}2{BETA} HETEROOLIGOMERIC ASPARTATE KINASE FROM CORYNEBACTER GLUTAMICUM J.BIOL.CHEM. V. 285 27477 2010
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 3AAW - THR C4 H9 N O3 C[C@H]([C@....
2 3AB4 - THR C4 H9 N O3 C[C@H]([C@....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 3AAW - THR C4 H9 N O3 C[C@H]([C@....
2 3AB4 - THR C4 H9 N O3 C[C@H]([C@....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3AAW - THR C4 H9 N O3 C[C@H]([C@....
2 3AB4 - THR C4 H9 N O3 C[C@H]([C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LYS; Similar ligands found: 44
No: Ligand ECFP6 Tc MDL keys Tc
1 LYS 1 1
2 LYN 0.612903 0.741935
3 DLY 0.59375 0.962963
4 API 0.586207 0.733333
5 DHH 0.575758 0.709677
6 NPI 0.558824 0.709677
7 ORN 0.53125 0.925926
8 M3L 0.527778 0.604651
9 NLE 0.515152 0.677419
10 6HN 0.513514 0.604651
11 MLY 0.513514 0.641026
12 MLZ 0.513514 0.764706
13 ALY 0.512821 0.742857
14 11C 0.5 0.677419
15 6CL 0.5 0.766667
16 UN1 0.5 0.677419
17 HRG 0.475 0.764706
18 ONH 0.472222 0.694444
19 EXY 0.463415 0.621622
20 NOT 0.463415 0.764706
21 26P 0.459459 0.617647
22 HSE 0.451613 0.6875
23 DAB 0.451613 0.827586
24 CIR 0.447368 0.694444
25 HCS 0.4375 0.758621
26 NVA 0.4375 0.666667
27 2NP 0.435897 0.611111
28 ARG 0.435897 0.764706
29 DAR 0.435897 0.764706
30 REZ 0.422222 0.621622
31 5CT 0.413043 0.742857
32 DGL 0.411765 0.645161
33 GGL 0.411765 0.645161
34 DGN 0.411765 0.636364
35 GLN 0.411765 0.636364
36 GLU 0.411765 0.645161
37 ILO 0.404762 0.714286
38 SHR 0.404255 0.8125
39 0TF 0.404255 0.722222
40 2RA 0.4 0.733333
41 ABA 0.4 0.62069
42 DSN 0.4 0.645161
43 SER 0.4 0.645161
44 DBB 0.4 0.62069
Ligand no: 2; Ligand: THR; Similar ligands found: 11
No: Ligand ECFP6 Tc MDL keys Tc
1 THR 1 1
2 VAL 0.65 0.714286
3 DAL 0.578947 0.789474
4 ALA 0.578947 0.789474
5 VAH 0.541667 0.76
6 ILE 0.541667 0.6
7 HGY 0.526316 0.625
8 AHB 0.5 0.6
9 ABA 0.434783 0.625
10 DBB 0.434783 0.625
11 LFC 0.407407 0.619048
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3AB4; Ligand: LYS; Similar sites found: 52
This union binding pocket(no: 1) in the query (biounit: 3ab4.bio4) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1WUW TSU 0.02217 0.40005 None
2 5E4R NAP 0.02476 0.40228 2.24719
3 5EZ7 FAD 0.01192 0.42914 3.06122
4 4QAR ADE 0.008932 0.404 3.08789
5 2WPF FAD 0.0401 0.42984 3.37079
6 2WPF WPF 0.04953 0.42585 3.37079
7 4NZ6 DGL 0.01869 0.40036 3.37079
8 4M52 FAD 0.006326 0.44607 4.27553
9 1FL2 FAD 0.007892 0.43827 4.49438
10 4J4H NAI 0.02153 0.42202 4.49438
11 4J4H 1J1 0.02153 0.42202 4.49438
12 4RW3 SHV 0.004316 0.41173 4.49438
13 5MW4 5JU 0.03569 0.40561 4.49438
14 4I8P NAD 0.03299 0.4006 4.49438
15 2F5Z FAD 0.02471 0.41646 4.6875
16 4UP3 FAD 0.005207 0.44846 4.77707
17 2NVK FAD 0.02518 0.41432 5.05618
18 2HQM FAD 0.02651 0.41403 5.05618
19 1N62 FAD 0.02313 0.41348 5.05618
20 2GAG FAD 0.04008 0.4071 5.05618
21 4M7V NAP 0.01964 0.40968 5.14286
22 2Z48 NGA 0.01205 0.41461 5.61798
23 2RGO FAD 0.02851 0.40788 5.61798
24 1TDF NAP 0.03565 0.42384 6.17978
25 1TDF FAD 0.01987 0.42384 6.17978
26 3LAD FAD 0.04399 0.40259 6.17978
27 1FFU FAD 0.028 0.4073 6.27178
28 1GXU 2HP 0.01551 0.41499 6.59341
29 1XVV CCQ 0.03354 0.40612 6.74157
30 3RNM FAD 0.01836 0.42314 6.89655
31 1O9J NAD 0.02291 0.40517 7.30337
32 4GLL NAD 0.01242 0.42079 7.71513
33 3A4V NAD 0.02753 0.40768 7.88644
34 3A4V PYR 0.02753 0.40768 7.88644
35 4B2D FBP 0.008032 0.40828 8.42697
36 4IP7 FBP 0.005347 0.41651 8.55107
37 1WVG APR 0.01715 0.4062 8.98876
38 4AGQ P96 0.01355 0.40153 9.58904
39 3AD8 PYC 0.04856 0.41433 9.85222
40 3AD8 FAD 0.04856 0.41433 9.85222
41 4YRY NAD 0.02041 0.42772 10.1124
42 5TWJ SAM 0.009908 0.40978 10.4938
43 5JCA FAD 0.02236 0.41786 11.2676
44 2RAB FAD 0.02642 0.41578 11.7978
45 2RAB NAD 0.0457 0.41578 11.7978
46 1V59 FAD 0.02172 0.42102 11.8765
47 5FII PHE 0.001844 0.41992 14.7059
48 1FEC FAD 0.01359 0.43244 18.5393
49 1PS9 FAD 0.02192 0.41742 20.7865
50 5GS9 ARG 0.000008055 0.5445 21.9101
51 4YDD MGD 0.02458 0.43319 21.9101
52 4YDD MD1 0.02458 0.43319 21.9101
Pocket No.: 2; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: 97
This union binding pocket(no: 2) in the query (biounit: 3ab4.bio4) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1ZUI SKM 0.04546 0.40141 None
2 3MMG GLU THR VAL ARG PHE GLN SER ASP 0.02094 0.411 1.1236
3 1RYA GDP 0.006878 0.43439 1.25
4 1BXK NAD 0.01647 0.419 3.09859
5 5H86 BCO 0.02251 0.41068 3.57143
6 1QSR ACO 0.01595 0.41428 3.7037
7 1O9U ADZ 0.004549 0.4375 3.93258
8 4EN4 ATP 0.01937 0.4242 3.93258
9 4EN4 GT1 0.01937 0.4242 3.93258
10 4EN4 GT0 0.01937 0.4242 3.93258
11 1H5Q NAP 0.01768 0.41983 3.93258
12 3IID APR 0.01837 0.41525 3.93258
13 3D9F N6C 0.04688 0.41398 3.93258
14 3D9F FAD 0.04688 0.41398 3.93258
15 5H2D ERG 0.01854 0.40792 3.93258
16 1GOJ ADP 0.01569 0.40789 3.93258
17 4E1Z 0MX 0.02163 0.40453 3.93258
18 3D3W NAP 0.03579 0.40374 3.93258
19 3TMK T5A 0.02771 0.40843 4.16667
20 2CWH PYC 0.005953 0.44693 4.49438
21 2CWH NDP 0.004748 0.44693 4.49438
22 4D86 ADP 0.005421 0.43132 4.49438
23 3ICC NAP 0.02082 0.41726 4.49438
24 1QG6 TCL 0.03503 0.41571 4.49438
25 1QG6 NAD 0.03503 0.41571 4.49438
26 2ZPT A3P 0.04743 0.41438 4.49438
27 4PIV NDP 0.02619 0.41088 4.49438
28 4QDI ATP 0.01369 0.40134 4.49438
29 1Z06 GNP 0.01626 0.41236 4.7619
30 2X06 NAD 0.009432 0.42882 5.05618
31 1N62 FAD 0.01897 0.42567 5.05618
32 1V9N NDP 0.01798 0.42061 5.05618
33 3LRE ADP 0.01148 0.41648 5.05618
34 4Q9N NAI 0.03731 0.40279 5.05618
35 2JAH NDP 0.03892 0.40182 5.05618
36 2V2V V12 0.0305 0.41642 5.16605
37 2VAR ANP 0.01041 0.41892 5.61798
38 2Q1S NAI 0.03242 0.41755 5.61798
39 2IV2 MGD 0.02749 0.4151 5.61798
40 4JB1 NAP 0.04483 0.41292 5.61798
41 3FYH ADP 0.02227 0.4054 5.61798
42 4O1M NAD 0.02596 0.40992 5.71429
43 4XTX 590 0.01949 0.41392 5.92593
44 2J5V PCA 0.005722 0.43425 5.93824
45 3H4L ANP 0.01147 0.41682 5.93824
46 2V3V MGD 0.03936 0.42902 6.17978
47 1R6D DAU 0.04546 0.41542 6.17978
48 1R6D NAD 0.04673 0.41542 6.17978
49 3RLF ANP 0.01489 0.41274 6.17978
50 3MJE NDP 0.03251 0.40361 6.17978
51 1FFU FAD 0.04458 0.40383 6.27178
52 2VEZ G6P 0.03326 0.40427 6.31579
53 1UVC STE 0.02322 0.40998 6.59341
54 1GXU 2HP 0.01554 0.40178 6.59341
55 1CLU DBG 0.03239 0.415 6.62651
56 1GR0 NAD 0.03324 0.40867 6.74157
57 1VL0 NAI 0.01743 0.41372 7.19178
58 4HXY NDP 0.01879 0.41845 7.30337
59 1HXD BTN 0.01403 0.41071 7.30337
60 3OJF IMJ 0.04341 0.40896 7.393
61 4GLL NAD 0.03564 0.40494 7.71513
62 3A4V PYR 0.03488 0.40957 7.88644
63 3A4V NAD 0.03488 0.40957 7.88644
64 2I8T GDD 0.007236 0.43327 8.38323
65 4B2D FBP 0.004019 0.43171 8.42697
66 1ATL 0QI 0.01091 0.41956 8.42697
67 5XDT MB3 0.03591 0.40585 8.42697
68 4RVU NDP 0.0417 0.40342 8.42697
69 4IP7 FBP 0.007123 0.41954 8.55107
70 1R2Q GNP 0.01563 0.42493 9.41177
71 4OSP NAP 0.02367 0.4108 9.5057
72 1XSE NDP 0.0303 0.41658 9.55056
73 1FIQ FAD 0.02473 0.4155 10.1124
74 3HRD FAD 0.03153 0.41652 10.1351
75 3T7V SAM 0.0181 0.40685 10.6742
76 4G31 0WH 0.03586 0.4048 10.6742
77 2ALG DAO 0.008238 0.42403 10.8696
78 2ALG HP6 0.008238 0.42403 10.8696
79 2PZM UDP 0.01184 0.44128 11.236
80 2PZM NAD 0.01184 0.44128 11.236
81 3KC1 2T6 0.01005 0.41612 11.276
82 1RYD GLC 0.0133 0.40774 12.9213
83 5G41 AP5 0.036 0.41506 13.5392
84 4P32 ADP 0.01567 0.41 14.0562
85 3QWI NAP 0.04378 0.4002 14.6067
86 5FII PHE 0.00001175 0.53284 14.7059
87 3AWJ COA 0.004837 0.43188 15.1685
88 4MN3 ACE PHE ALA TYR M3L SER NH2 0.01064 0.40889 16.0714
89 4AG5 ADP 0.01098 0.4098 16.2921
90 2FSH ANP 0.007465 0.4091 16.8539
91 2BKK ADP 0.009288 0.40951 17.7515
92 2YY7 NAD 0.03927 0.40161 17.9775
93 3C6K SPD 0.01938 0.42319 21.3483
94 3C6K MTA 0.01938 0.42319 21.3483
95 5GS9 ARG 0.0002226 0.4905 21.9101
96 3QF7 ANP 0.01749 0.40416 28
97 4U9W COA 0.04477 0.40649 28.5024
Pocket No.: 3; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 3ab4.bio4) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 3ab4.bio4) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 3ab4.bio4) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 3AB4; Ligand: LYS; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 3ab4.bio4) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 3AB4; Ligand: LYS; Similar sites found: 11
This union binding pocket(no: 7) in the query (biounit: 3ab4.bio1) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3PA8 621 0.01776 0.40438 2.24719
2 3EAU PDN 0.02799 0.40075 2.80899
3 4UXU MLK 0.02048 0.40928 3.21101
4 1Q7E MET 0.01112 0.40936 3.93258
5 1P1C SAH 0.01128 0.40467 4.52261
6 4KVX ACO 0.01699 0.40075 5.12821
7 1J0D 5PA 0.006972 0.41738 7.30337
8 3UEC ALA ARG TPO LYS 0.009772 0.41837 8.90411
9 4FMS BDP 0.008872 0.4196 8.98876
10 1RJD SAM 0.005906 0.41054 10.1124
11 3RF4 FUN 0.01207 0.41286 16.3793
Pocket No.: 8; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 3ab4.bio1) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: 93
This union binding pocket(no: 9) in the query (biounit: 3ab4.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4N14 WR7 0.009272 0.41134 2.24719
2 3HAV ATP 0.004138 0.40186 2.24719
3 3KO8 NAD 0.03481 0.40181 2.24719
4 2GQR ADP 0.00602 0.41848 2.80899
5 5TO8 7FM 0.02339 0.41593 2.80899
6 4CLI 5P8 0.0471 0.40351 2.80899
7 2PYW ADP 0.01852 0.40064 2.80899
8 3ZS7 ATP 0.01511 0.40827 3.33333
9 1W2D ADP 0.002147 0.43244 3.37079
10 2GQS ADP 0.004203 0.42592 3.37079
11 4XDA ADP 0.01808 0.41644 3.37079
12 4XDA RIB 0.01808 0.41644 3.37079
13 4O4K 2PK 0.01701 0.40574 3.37079
14 4NZ6 DGL 0.01698 0.40076 3.37079
15 2AQX ATP 0.01312 0.40967 3.80048
16 2PUL ACP 0.003814 0.42794 3.93258
17 3F7Z 34O 0.007988 0.41465 3.93258
18 4XQC 13D 0.03524 0.4127 3.93258
19 2IO8 ADP 0.01444 0.41081 3.93258
20 4XH0 ADP 0.01069 0.41005 3.93258
21 3CY2 MB9 0.01505 0.40836 3.93258
22 4XQC NAD 0.04188 0.40788 3.93258
23 2XK9 XK9 0.0301 0.40721 3.93258
24 4GYI ADP 0.006759 0.40096 3.93258
25 5VCV 1N1 0.02299 0.40079 3.93258
26 4WZ8 3W7 0.02675 0.41656 4.038
27 3R4S SIA 0.007878 0.41158 4.038
28 5MW8 ATP 0.01026 0.41657 4.49438
29 2WTX VDO 0.03659 0.40479 4.49438
30 2WTX UDP 0.03504 0.40479 4.49438
31 2VPQ ANP 0.01814 0.40436 4.49438
32 4J4H 1J1 0.04937 0.40405 4.49438
33 4DFU QUE 0.01441 0.4024 4.49438
34 4D42 NAP 0.03955 0.41378 4.60993
35 4D42 W0I 0.03955 0.41378 4.60993
36 5MY8 RXZ 0.02456 0.40081 4.96084
37 4GID 0GH 0.04951 0.40917 4.98812
38 2CSN CKI 0.02486 0.40194 5.05051
39 4A4X JUP 0.009374 0.42312 5.05618
40 3M2W L8I 0.007216 0.41027 5.05618
41 4IX4 ADP 0.01473 0.40549 5.05618
42 5U6C 7YS 0.01045 0.4145 5.07937
43 5VC5 96M 0.02694 0.40152 5.19031
44 5W2I I3P 0.01035 0.41797 5.44747
45 5W2I ADP 0.01035 0.41797 5.44747
46 4M20 COA 0.02238 0.40137 5.51181
47 1OBD ATP 0.001797 0.43867 5.55556
48 1Y0Y L2O VAL VAL ASP 0.006543 0.41227 5.61798
49 3X01 AMP 0.01256 0.40805 5.61798
50 5EYK 5U5 0.02015 0.40788 5.61798
51 5DEY 59T 0.03093 0.40761 5.61798
52 4X9M FAD 0.04374 0.40437 5.61798
53 4C2V YJA 0.02959 0.40197 5.61798
54 5IOK ACE GLN THR ALA ARG KCR SER THR 0.01483 0.4172 5.6338
55 4KQI RBZ 0.02908 0.40471 5.70071
56 2OFV 242 0.02605 0.41046 6.17978
57 5HX8 66P 0.01886 0.40795 6.17978
58 5LVP ATP 0.01042 0.40273 6.17978
59 5F7N NAG GAL FUC FUC A2G 0.02131 0.40243 6.17978
60 4OAV ACP 0.0135 0.40171 6.17978
61 4O1P ANP 0.01541 0.4009 6.17978
62 3NIP 16D 0.01661 0.40179 6.44172
63 5KO1 6UY 0.01174 0.40461 6.65083
64 3RI1 3RH 0.01435 0.4139 6.74157
65 3PLS ANP 0.01129 0.40542 6.74157
66 5HSA FAS 0.04538 0.40437 6.88836
67 5CUO COA 0.008694 0.41665 6.93069
68 2XG5 EC5 0.01079 0.40435 6.93642
69 2XG5 EC2 0.01079 0.40435 6.93642
70 1ZC3 GNP 0.02215 0.40445 7.42857
71 4WW7 AMP 0.008709 0.41837 8.02139
72 4YZN 4K5 0.02187 0.40034 8.36237
73 3ZRM ZRM 0.005254 0.42339 8.42697
74 4CQM NAP 0.02828 0.40417 8.42697
75 5N87 N66 0.03758 0.40219 8.42697
76 3JYN NDP 0.02152 0.41367 8.92308
77 4E93 GUI 0.02767 0.40582 9.55056
78 3NUG NAD 0.01371 0.42141 9.7166
79 3UDZ ADP 0.01099 0.40989 9.73872
80 5UOX 8GY 0.01312 0.40966 10.1124
81 3DLS ADP 0.00943 0.40704 10.1124
82 1MEX RAC 0.008285 0.40504 10.1124
83 4BHN BH9 0.01794 0.40131 10.1124
84 3LXN MI1 0.01554 0.40436 10.6742
85 4PVV HO4 0.02584 0.41462 11.236
86 3TXO 07U 0.01235 0.40146 11.236
87 2HGS ADP 0.02088 0.40133 11.7978
88 3FXU TSU 0.0173 0.40841 12.7869
89 1UAD GNP 0.0234 0.40185 13.1313
90 4YMJ 4EJ 0.01276 0.406 13.4831
91 5A6N U7E 0.01257 0.40706 15.7303
92 1FEC FAD 0.02291 0.42429 18.5393
93 4WNP 3RJ 0.0118 0.40019 21.9101
Pocket No.: 10; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 3ab4.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 3ab4.bio1) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 3AB4; Ligand: LYS; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 3ab4.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 13; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: 14
This union binding pocket(no: 13) in the query (biounit: 3ab4.bio3) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3B2Q ATP 0.01883 0.4051 3.19829
2 4LRJ ANP 0.01447 0.40026 3.5503
3 1BZL FAD 0.0457 0.43036 4.49438
4 1L1Q 9DA 0.01741 0.40195 4.83871
5 4UAL 3FV 0.01463 0.402 5.05618
6 4GJ3 0XP 0.02211 0.40963 5.29801
7 1ORR NAD 0.03389 0.40348 6.91643
8 4MV1 ADP 0.02997 0.40404 10.6742
9 2E2R 2OH 0.03122 0.40638 11.0656
10 4AXD ANP 0.01937 0.4192 12.2807
11 3TN7 NJP 0.03569 0.40014 14.0449
12 2RC8 DSN 0.01736 0.40033 16.8539
13 4Z24 FAD 0.008441 0.44383 17.9775
14 1PS9 FMN 0.01564 0.40754 20.7865
Pocket No.: 14; Query (leader) PDB : 3AB4; Ligand: LYS; Similar sites found: 27
This union binding pocket(no: 14) in the query (biounit: 3ab4.bio3) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1EB1 ZAL PRO MMO 0.03234 0.40491 3.11284
2 1E1M FAD 0.04609 0.41575 3.93258
3 2HK9 NAP 0.02643 0.40577 3.93258
4 4V3C C 0.007935 0.41724 4.63918
5 2GAG FOA 0.02565 0.42472 5.05618
6 3FG2 FAD 0.01597 0.42445 5.05618
7 4M7V RAR 0.02775 0.42123 5.14286
8 5WB6 9ZM 0.01937 0.41274 5.32787
9 4JB1 NAP 0.02617 0.42582 5.61798
10 4JB1 FAD 0.02701 0.42582 5.61798
11 4OE4 NAD 0.01615 0.40588 5.61798
12 4QYS PLP SEP 0.02363 0.40554 5.61798
13 5IOK ACE GLN THR ALA ARG KCR SER THR 0.02321 0.41125 5.6338
14 4SGA ACE PRO ALA PRO PHE 0.01561 0.40074 6.07735
15 4R84 CSF 0.00581 0.42388 6.17577
16 1CLU DBG 0.04055 0.40972 6.62651
17 4PZ2 NAD 0.0376 0.40261 6.74157
18 3ITJ FAD 0.04561 0.41323 7.86517
19 3IWJ NAD 0.01657 0.40347 7.86517
20 5XDT GDP 0.02506 0.40696 8.42697
21 2IVF MD1 0.04598 0.40115 8.42697
22 5L2Z 70C 0.04596 0.40116 8.62069
23 3UYK 0CX 0.02359 0.41763 11.7978
24 4KXQ APR 0.02342 0.40277 11.7978
25 4I5I NAD 0.02756 0.40612 12.892
26 4J56 FAD 0.04849 0.40876 12.9213
27 1TMT DPN PRO ARG 0.01468 0.40794 44.4444
Pocket No.: 15; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 15) in the query (biounit: 3ab4.bio3) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 16; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 16) in the query (biounit: 3ab4.bio3) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 17; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 17) in the query (biounit: 3ab4.bio3) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 18; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 18) in the query (biounit: 3ab4.bio2) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 19; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 19) in the query (biounit: 3ab4.bio2) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 20; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: 35
This union binding pocket(no: 20) in the query (biounit: 3ab4.bio2) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2ZMF CMP 0.02109 0.4001 3.1746
2 1VG8 GNP 0.02808 0.40308 3.38164
3 3SRV S19 0.01588 0.40244 3.93258
4 1XJD STU 0.01943 0.40188 3.93258
5 1W6U NAP 0.02795 0.4018 3.97351
6 4M52 FAD 0.04429 0.40932 4.27553
7 1NVM NAD 0.007336 0.44218 4.49438
8 1V35 NAI 0.02974 0.41789 4.49438
9 4JWH SAH 0.01109 0.41754 4.49438
10 4OTH DRN 0.0232 0.40141 4.49438
11 4J1Q NDP 0.0193 0.41414 5.05618
12 3DAK ANP 0.01231 0.40579 5.05618
13 3OIG NAD 0.01439 0.42073 5.61798
14 3TKI S25 0.03845 0.41807 5.61798
15 5LI1 ANP 0.01873 0.40609 5.61798
16 4WT2 3UD 0.03017 0.40407 5.71429
17 3MVH WFE 0.02653 0.40822 6.17978
18 4F9C 0SX 0.0148 0.40395 6.17978
19 2PHN GDP 0.02008 0.40769 6.29921
20 5NJI 8Z2 0.01869 0.41354 6.74157
21 2X4Z X4Z 0.03392 0.40716 7.09459
22 2CYE COA 0.01252 0.4149 7.30337
23 4QMN DB8 0.02679 0.41366 7.86517
24 4R08 UCG 0.01683 0.40314 7.86517
25 4L3L 5FI 0.03075 0.40487 7.89474
26 4NM5 ADP 0.0122 0.41711 8.42697
27 4D2S DYK 0.008357 0.41173 8.42697
28 5XDT ZI7 0.0284 0.40415 8.42697
29 1YKD CMP 0.01348 0.40791 8.98876
30 1WDK NAD 0.0275 0.40073 8.98876
31 5NB7 8NQ 0.02141 0.40475 9.55056
32 5USZ SKE 0.03087 0.40227 11.236
33 3RE4 TO1 0.01522 0.40335 12.3596
34 4EUU BX7 0.03084 0.40097 12.3596
35 3WMX THR 0.02111 0.41175 14.8045
Pocket No.: 21; Query (leader) PDB : 3AB4; Ligand: THR; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 21) in the query (biounit: 3ab4.bio2) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 22; Query (leader) PDB : 3AB4; Ligand: LYS; Similar sites found: 6
This union binding pocket(no: 22) in the query (biounit: 3ab4.bio2) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4DQ2 BTX 0.02598 0.40124 3.37079
2 1N62 MCN 0.03828 0.40036 5.05618
3 1ORR NAD 0.0173 0.4136 6.91643
4 4YRY FAD 0.04424 0.40245 10.1124
5 3LTW HLZ 0.01916 0.40158 12.9213
6 2YY7 NAD 0.02561 0.40392 17.9775
Pocket No.: 23; Query (leader) PDB : 3AB4; Ligand: LYS; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 23) in the query (biounit: 3ab4.bio2) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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