Receptor
PDB id Resolution Class Description Source Keywords
3A4T 2.3 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF ATRM4 FROM M.JANNASCHII WITH SINEFUNGIN METHANOCALDOCOCCUS JANNASCHII TRNAM5CROSSMANN FOLD STRUCTURAL GENOMICSRSGI RIKEN STRUGENOMICS/PROTEOMICS INITIATIVE METHYLTRANSFERASE S-ADENOSMETHIONINE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII COMPLEXED WITH SINEFUNGIN. J.MOL.BIOL. V. 401 323 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SFG A:500;
B:501;
Valid;
Valid;
none;
none;
submit data
381.387 C15 H23 N7 O5 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3A4T 2.3 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF ATRM4 FROM M.JANNASCHII WITH SINEFUNGIN METHANOCALDOCOCCUS JANNASCHII TRNAM5CROSSMANN FOLD STRUCTURAL GENOMICSRSGI RIKEN STRUGENOMICS/PROTEOMICS INITIATIVE METHYLTRANSFERASE S-ADENOSMETHIONINE TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF METHANOCALDOCOCCUS JANNASCHII COMPLEXED WITH SINEFUNGIN. J.MOL.BIOL. V. 401 323 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 3A4T - SFG C15 H23 N7 O5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 3A4T - SFG C15 H23 N7 O5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 3A4T - SFG C15 H23 N7 O5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SFG; Similar ligands found: 218
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 RAB 0.597222 0.850746
10 XYA 0.597222 0.850746
11 ADN 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 ZAS 0.53012 0.816901
26 A 0.53012 0.77027
27 AMP 0.53012 0.77027
28 J7C 0.529412 0.84507
29 3DH 0.52439 0.826087
30 GJV 0.523256 0.821918
31 SON 0.522727 0.813333
32 0XU 0.522222 0.938462
33 SRP 0.521277 0.813333
34 SSA 0.521277 0.697674
35 AMP MG 0.517647 0.75
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 AMO 0.515464 0.813333
40 DSZ 0.515464 0.717647
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 A2D 0.511628 0.75
44 A3N 0.511628 0.814286
45 ABM 0.511628 0.75
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 AN2 0.505618 0.74026
51 A7D 0.505618 0.882353
52 A3S 0.505618 0.895522
53 GAP 0.505376 0.776316
54 LSS 0.5 0.681818
55 VMS 0.5 0.666667
56 DSH 0.5 0.871429
57 AP2 0.5 0.766234
58 LAD 0.5 0.818182
59 ADX 0.5 0.678571
60 BA3 0.5 0.75
61 M33 0.5 0.74026
62 A12 0.5 0.766234
63 KAA 0.5 0.712644
64 54H 0.5 0.666667
65 Y3J 0.5 0.80303
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 TSB 0.494845 0.674419
70 53H 0.494845 0.659091
71 G5A 0.494624 0.697674
72 50T 0.494505 0.74026
73 AP5 0.494382 0.75
74 5AS 0.494382 0.640449
75 ADP 0.494382 0.75
76 B4P 0.494382 0.75
77 8QN 0.489796 0.786667
78 GEK 0.489796 0.913043
79 5AD 0.486842 0.828125
80 PAJ 0.484848 0.728395
81 52H 0.484536 0.659091
82 AU1 0.483516 0.730769
83 ADP MG 0.483516 0.74026
84 MAO 0.483146 0.782051
85 NEC 0.482759 0.797101
86 A3G 0.482759 0.882353
87 3AM 0.482353 0.733333
88 YAP 0.480769 0.802632
89 7D7 0.480519 0.794118
90 TXA 0.480392 0.766234
91 NB8 0.480392 0.782051
92 NVA LMS 0.48 0.681818
93 DAL AMP 0.479592 0.786667
94 ATF 0.479167 0.721519
95 ATP 0.478261 0.75
96 BEF ADP 0.478261 0.721519
97 ACP 0.478261 0.753247
98 ADP BEF 0.478261 0.721519
99 A3T 0.478261 0.852941
100 7MD 0.476636 0.775
101 XAH 0.47619 0.775
102 YSA 0.47619 0.697674
103 PRX 0.473118 0.753247
104 APR 0.473118 0.773333
105 AR6 0.473118 0.773333
106 AQP 0.473118 0.75
107 APC 0.473118 0.766234
108 5FA 0.473118 0.75
109 WAQ 0.470588 0.815789
110 4AD 0.47 0.802632
111 NSS 0.47 0.697674
112 AD9 0.468085 0.730769
113 RBY 0.468085 0.789474
114 AGS 0.468085 0.7125
115 SAP 0.468085 0.7125
116 ADV 0.468085 0.789474
117 ADP PO3 0.468085 0.77027
118 A5D 0.468085 0.84058
119 MHZ 0.467391 0.782051
120 FA5 0.466667 0.813333
121 PTJ 0.466019 0.7375
122 00A 0.465347 0.746835
123 D3Y 0.464646 0.869565
124 ATP MG 0.463158 0.74026
125 VRT 0.463158 0.871429
126 LEU LMS 0.460784 0.662921
127 OOB 0.46 0.786667
128 S8M 0.46 0.859155
129 ADP VO4 0.459184 0.74026
130 VO4 ADP 0.459184 0.74026
131 ACQ 0.458333 0.753247
132 TAT 0.458333 0.721519
133 ANP 0.458333 0.730769
134 AAT 0.453608 0.847222
135 2AM 0.453488 0.723684
136 FYA 0.451923 0.786667
137 YLC 0.451327 0.797468
138 DLL 0.45098 0.786667
139 A3P 0.450549 0.746667
140 YLP 0.45045 0.777778
141 A22 0.45 0.74026
142 ADP ALF 0.44898 0.7125
143 ALF ADP 0.44898 0.7125
144 TYR AMP 0.448598 0.789474
145 2VA 0.446809 0.828571
146 3UK 0.446602 0.776316
147 OAD 0.446602 0.776316
148 ANP MG 0.444444 0.7125
149 IOT 0.443478 0.768293
150 9SN 0.443396 0.7375
151 P5A 0.442308 0.704545
152 PR8 0.442308 0.807692
153 7D5 0.44186 0.714286
154 A1R 0.441176 0.769231
155 7C5 0.440367 0.797297
156 TT8 0.44 0.926471
157 YLA 0.439655 0.777778
158 YLB 0.438596 0.777778
159 1ZZ 0.438095 0.753086
160 3OD 0.438095 0.776316
161 BIS 0.438095 0.725
162 NVA 2AD 0.4375 0.816901
163 MAP 0.435644 0.7125
164 MYR AMP 0.433962 0.753086
165 NAI 0.433628 0.725
166 SO8 0.43299 0.816901
167 A6D 0.432692 0.74359
168 5SV 0.431373 0.7375
169 25A 0.431373 0.75
170 TYM 0.429825 0.813333
171 WSA 0.429825 0.705882
172 3NZ 0.428571 0.833333
173 ARG AMP 0.428571 0.765432
174 LAQ 0.428571 0.753086
175 ADQ 0.427184 0.753247
176 7MC 0.426087 0.756098
177 48N 0.424779 0.759494
178 LPA AMP 0.424779 0.753086
179 JB6 0.424528 0.746835
180 PPS 0.424242 0.658824
181 AYB 0.423729 0.768293
182 PAP 0.42268 0.736842
183 OVE 0.422222 0.696203
184 3AD 0.421687 0.863636
185 4YB 0.419643 0.72093
186 CMP 0.419355 0.753425
187 2BA 0.419355 0.743243
188 A2P 0.419355 0.733333
189 ADP BMA 0.419048 0.753247
190 4UV 0.418182 0.75641
191 ALF ADP 3PG 0.417391 0.75
192 LA8 ALF 3PG 0.417391 0.75
193 AHZ 0.415929 0.731707
194 QQX 0.41573 0.670886
195 A A 0.415094 0.75
196 AP0 0.413793 0.695122
197 ATP A A A 0.412844 0.76
198 RP1 0.411111 0.705128
199 QQY 0.411111 0.679487
200 SP1 0.411111 0.705128
201 ACK 0.411111 0.716216
202 AFH 0.410714 0.728395
203 4UU 0.410714 0.75641
204 DND 0.408696 0.766234
205 TXD 0.408696 0.725
206 NXX 0.408696 0.766234
207 7D3 0.408602 0.696203
208 25L 0.407407 0.74026
209 CC5 0.407407 0.876923
210 TAD 0.40708 0.75
211 AMP DBH 0.405405 0.753247
212 TXE 0.405172 0.725
213 OMR 0.405172 0.743902
214 AF3 ADP 3PG 0.405172 0.75
215 MTP 0.404762 0.72973
216 N0B 0.401575 0.777778
217 V3L 0.4 0.773333
218 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3A4T; Ligand: SFG; Similar sites found: 543
This union binding pocket(no: 1) in the query (biounit: 3a4t.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1WUW TSU 0.0228 0.40895 None
2 5THQ NDP 0.001492 0.43497 0.735294
3 3WV8 ATP 0.0007047 0.42987 0.917431
4 2DPM SAM 0.000007227 0.51886 1.09489
5 1UXG NAD 0.01262 0.40425 1.09489
6 5X62 SAH 0.00006767 0.45621 1.45985
7 1L1E SAH 0.0004065 0.44257 1.45985
8 3CH6 NAP 0.008447 0.42901 1.45985
9 3CH6 311 0.008447 0.42901 1.45985
10 4AT0 FAD 0.008669 0.41966 1.45985
11 1P77 ATR 0.02429 0.40612 1.47059
12 4OSP NAP 0.006743 0.40571 1.52091
13 5N53 8NB 0.01653 0.41391 1.53846
14 1ELI PYC 0.0002445 0.47955 1.82482
15 4TXI FAD 0.0004604 0.45965 1.82482
16 5T67 SAH 0.002053 0.44112 1.82482
17 5T67 JHZ 0.002748 0.44041 1.82482
18 5JGL SAM 0.0003259 0.4329 1.82482
19 3LXD FAD 0.002556 0.43137 1.82482
20 4BJZ P3A 0.01008 0.43033 1.82482
21 4RDH AMP 0.00328 0.42763 1.82482
22 2XVF FAD 0.005038 0.42076 1.82482
23 2XVE FAD 0.01403 0.4181 1.82482
24 1FP2 SAH 0.005846 0.41574 1.82482
25 2Q28 ADP 0.001429 0.41571 1.82482
26 1DJN ADP 0.002761 0.41445 1.82482
27 5EZ7 FAD 0.009133 0.41145 1.82482
28 5L13 6ZE 0.02567 0.40047 1.82482
29 3QWI CUE 0.003837 0.43011 1.85185
30 3QWI NAP 0.002242 0.43011 1.85185
31 3RKR NAP 0.0002322 0.42013 1.9084
32 1Q0S SAH 0.000002432 0.54311 1.9305
33 3AFN NAP 0.001482 0.43915 1.93798
34 2Z3Y F2N 0.0001903 0.49025 2.18978
35 4ZCC FAD 0.0004467 0.48066 2.18978
36 4ZCC NAI 0.0004467 0.48066 2.18978
37 3S5W FAD 0.0002027 0.47344 2.18978
38 4FWE FAD 0.0007091 0.46478 2.18978
39 3P9C SAH 0.0004843 0.4587 2.18978
40 2RAB FAD 0.001357 0.45319 2.18978
41 2RAB NAD 0.003001 0.45264 2.18978
42 2BRY FAD 0.0007586 0.4517 2.18978
43 5BVA FAD 0.002233 0.44352 2.18978
44 2AQJ FAD 0.006947 0.43161 2.18978
45 2AQJ TRP 0.006709 0.43161 2.18978
46 3ZV6 NAD 0.003902 0.42979 2.18978
47 3ZV6 4HB 0.004104 0.42979 2.18978
48 5F8F SFG 0.0005145 0.41688 2.18978
49 4CM9 NAP 0.005076 0.41229 2.18978
50 5K6A NAP 0.005444 0.411 2.18978
51 4CME NAP 0.005065 0.41099 2.18978
52 3BMN NAP 0.00549 0.41084 2.18978
53 3JQ8 NAP 0.00611 0.40886 2.18978
54 3ITJ FAD 0.01723 0.4069 2.18978
55 5JDC NAP 0.006405 0.40666 2.18978
56 3JQ9 NAP 0.006902 0.40659 2.18978
57 4CLR NAP 0.006498 0.40639 2.18978
58 5JDI NAP 0.006827 0.40548 2.18978
59 5UAO FAD 0.01189 0.40539 2.18978
60 4CLO NAP 0.006383 0.40536 2.18978
61 4CM8 NAP 0.007789 0.40305 2.18978
62 1VDC FAD 0.02164 0.40161 2.18978
63 1VE3 SAM 0.00002189 0.51499 2.20264
64 1TE2 PGA 0.02941 0.40528 2.21239
65 2VZ0 NAP 0.02798 0.41187 2.23881
66 2VZ0 D64 0.02798 0.41187 2.23881
67 2WD7 NAP 0.006549 0.40625 2.23881
68 5BW4 SAM 0.000005079 0.50147 2.24719
69 3RFV 15L 0.001525 0.43009 2.24719
70 3RFV NAI 0.002818 0.42037 2.24719
71 2A14 SAH 0.002028 0.41823 2.28137
72 1OAA OAA 0.008312 0.41704 2.3166
73 2BES RES 0.01835 0.40033 2.32558
74 4NBW NAD 0.003951 0.41417 2.33463
75 2Q2V NAD 0.007954 0.40764 2.35294
76 4YMH SAH 0.00001172 0.50395 2.5
77 4BLW AMP 0.0000009187 0.57924 2.55474
78 4BLW SAH 0.0000004279 0.57924 2.55474
79 2ZIF SAM 0.0000001716 0.57053 2.55474
80 4LWP SAH 0.000001474 0.52516 2.55474
81 1U2Z SAH 0.0000142 0.50908 2.55474
82 2WA2 SAM 0.000006181 0.49628 2.55474
83 5GM1 SAH 0.00003448 0.49316 2.55474
84 4MO2 FDA 0.0004723 0.46578 2.55474
85 2WPF FAD 0.003268 0.4638 2.55474
86 4USQ FAD 0.000485 0.46143 2.55474
87 2WPF WPF 0.004997 0.45622 2.55474
88 4USR FAD 0.0007268 0.4525 2.55474
89 3U4C NDP 0.0005585 0.45162 2.55474
90 2V3B FAD 0.001008 0.45138 2.55474
91 3NTD FAD 0.001086 0.45112 2.55474
92 2V3A FAD 0.001148 0.45006 2.55474
93 1GY8 NAD 0.00102 0.44343 2.55474
94 5J60 FAD 0.002097 0.44072 2.55474
95 4NTC FAD 0.00243 0.43892 2.55474
96 3NT6 FAD 0.002802 0.43303 2.55474
97 2RGJ FAD 0.002139 0.43227 2.55474
98 2YYY NAP 0.001883 0.42923 2.55474
99 2Q1S NAI 0.004748 0.42792 2.55474
100 3V1U NAD 0.00176 0.42589 2.55474
101 4EIP K2C 0.006971 0.4231 2.55474
102 4EIP FAD 0.006971 0.4231 2.55474
103 1SB8 UD2 0.01022 0.41956 2.55474
104 1SB8 NAD 0.008712 0.41956 2.55474
105 1XSE NDP 0.006971 0.41762 2.55474
106 1JA9 NDP 0.004396 0.41754 2.55474
107 1EK6 NAI 0.0145 0.41333 2.55474
108 1YKJ PHB 0.02346 0.4089 2.55474
109 1YKJ FAD 0.02346 0.4089 2.55474
110 1R37 NAD 0.01129 0.40217 2.55474
111 2ZAT NAP 0.006978 0.40639 2.69231
112 4KIB SAH 0.000003473 0.5054 2.91971
113 2PT9 S4M 0.00003074 0.49935 2.91971
114 2PT9 2MH 0.00007178 0.49734 2.91971
115 4UCI SAM 0.0000184 0.48858 2.91971
116 4FC7 NAP 0.0002541 0.48354 2.91971
117 4FC7 COA 0.0002541 0.48354 2.91971
118 1RSG FAD 0.000271 0.48229 2.91971
119 5GWX SAM 0.0001128 0.47759 2.91971
120 5GWX SAR 0.0001128 0.47759 2.91971
121 1GET NAP 0.001585 0.46696 2.91971
122 1GET FAD 0.001483 0.46696 2.91971
123 1N4W FAD 0.0009652 0.4588 2.91971
124 1UWK NAD 0.001128 0.45777 2.91971
125 5JAQ NAI 0.001155 0.45107 2.91971
126 1LVL NAD 0.0004148 0.45059 2.91971
127 3KO8 NAD 0.001402 0.43887 2.91971
128 3G5S FAD 0.001995 0.43839 2.91971
129 4J36 1HR 0.003123 0.43604 2.91971
130 4J36 FAD 0.001758 0.43596 2.91971
131 5I39 FAD 0.002707 0.43369 2.91971
132 4HXY NDP 0.001954 0.43135 2.91971
133 5L53 NAP 0.001388 0.425 2.91971
134 2I7C AAT 0.00006902 0.41911 2.91971
135 2V6G NAP 0.004017 0.41795 2.91971
136 2PZM UDP 0.01047 0.41255 2.91971
137 2PZM NAD 0.01047 0.41255 2.91971
138 2DFV NAD 0.00538 0.4085 2.91971
139 2GDZ NAD 0.001028 0.44185 2.99625
140 3DZ6 M8E 0.002669 0.40121 2.99625
141 2WSB NAD 0.003355 0.43169 3.14961
142 2Q46 NAP 0.0007068 0.44728 3.16206
143 4ZA2 NAD 0.006958 0.40513 3.16206
144 3SJ7 NDP 0.003767 0.41645 3.1746
145 4YSX FAD 0.001432 0.44805 3.20513
146 3DXY SAM 0.000001842 0.59151 3.21101
147 3OU2 SAH 0.000004065 0.50412 3.21101
148 3G2O SAM 0.0000001698 0.60718 3.28467
149 1YY5 FAD 0.0004347 0.47531 3.28467
150 1QO8 FAD 0.0006671 0.4649 3.28467
151 4BV6 FAD 0.0008883 0.45831 3.28467
152 4A6D SAM 0.0003821 0.45631 3.28467
153 1VQW FAD 0.000703 0.45312 3.28467
154 2GVC FAD 0.0007223 0.45261 3.28467
155 4D04 NAP 0.0033 0.44869 3.28467
156 4D04 FAD 0.0033 0.44869 3.28467
157 5FJN BE2 0.001893 0.44767 3.28467
158 5FJN FAD 0.001627 0.44767 3.28467
159 1PN0 FAD 0.002096 0.44753 3.28467
160 1PN0 IPH 0.002193 0.44753 3.28467
161 2AOT SAH 0.0002822 0.43173 3.28467
162 2WET FAD 0.003745 0.43058 3.28467
163 3LCV SAM 0.001216 0.42918 3.28467
164 2CUL FAD 0.005348 0.41742 3.28467
165 3OJO NAD 0.002843 0.41392 3.28467
166 1P4A PCP 0.005984 0.412 3.28467
167 1T26 NAI 0.01054 0.41151 3.28467
168 1G8K MGD 0.02392 0.41142 3.28467
169 3F8D FAD 0.03137 0.4069 3.28467
170 2A92 NAI 0.008071 0.40618 3.28467
171 1JQD SAH 0.0006482 0.40387 3.28467
172 5CG1 NAD BBN 0.03076 0.40275 3.28467
173 2Z9I GLY ALA THR VAL 0.03176 0.40187 3.28467
174 5TUK FAD 0.00947 0.40072 3.28467
175 1U7T TDT 0.003244 0.43335 3.44828
176 3P2E SAH 0.0003099 0.4559 3.55556
177 1I9G SAM 0.0000005645 0.5573 3.64964
178 1Z3C SA8 0.000009481 0.52851 3.64964
179 3GCZ SAM 0.000002044 0.52206 3.64964
180 1Y8Q ATP 0.00005571 0.46811 3.64964
181 3E1T FAD 0.001227 0.45416 3.64964
182 1Q9I TEO 0.003622 0.44323 3.64964
183 5U8U FAD 0.006317 0.43685 3.64964
184 2BGM NAJ 0.002091 0.42433 3.64964
185 3H4V DVP 0.005897 0.42277 3.64964
186 4DSG UDP 0.01204 0.42119 3.64964
187 4DSG FAD 0.01204 0.42119 3.64964
188 3H4V NAP 0.01239 0.40747 3.64964
189 1N7G NDP 0.03519 0.40398 3.64964
190 4U7W NDP 0.007556 0.40225 3.64964
191 3MJE NDP 0.008749 0.4022 3.64964
192 1KC7 PPR 0.02583 0.40129 3.64964
193 1PR9 NAP 0.0006433 0.45478 3.68852
194 3D3W NAP 0.0006572 0.45438 3.68852
195 4CS9 AMP 0.001231 0.48419 3.7037
196 3Q87 SAM 0.00006864 0.48079 4
197 4N49 SAM 0.00000006993 0.59385 4.0146
198 4DCM SAM 0.000004556 0.49279 4.0146
199 2HQM FAD 0.0004717 0.47159 4.0146
200 1I8T FAD 0.0005363 0.46575 4.0146
201 1V59 FAD 0.0009334 0.46146 4.0146
202 1FP1 SAH 0.00005437 0.45659 4.0146
203 4D7E FAD 0.0007983 0.45459 4.0146
204 1RP0 AHZ 0.0007428 0.45073 4.0146
205 4AP3 NAP 0.00301 0.44914 4.0146
206 4AP3 FAD 0.00301 0.44914 4.0146
207 1WVG APR 0.0007303 0.44186 4.0146
208 1FEC FAD 0.003102 0.43895 4.0146
209 1V59 NAD 0.0001894 0.42507 4.0146
210 1WMA NDP 0.007082 0.42015 4.0146
211 1WMA AB3 0.007082 0.42015 4.0146
212 1BXK NAD 0.003537 0.41762 4.0146
213 1CF2 NAP 0.003854 0.41316 4.0146
214 2PK3 A2R 0.002001 0.41063 4.0146
215 2JAH NDP 0.003718 0.41939 4.04858
216 3C3Y SAH 0.00002067 0.48831 4.21941
217 3BGD SAH 0.00002729 0.49735 4.23077
218 3BGD PM6 0.00004439 0.49645 4.23077
219 3W9F I3P 0.0114 0.43815 4.23077
220 3TN7 NJP 0.004863 0.41439 4.28016
221 2BZG SAH 0.00001734 0.48627 4.31034
222 3S1S SAH 0.00000004814 0.59628 4.37956
223 4KRI SAH 0.000008258 0.50976 4.37956
224 3C6K SPD 0.0001484 0.48646 4.37956
225 3C6K MTA 0.0001484 0.48646 4.37956
226 1REO FAD 0.0002107 0.48363 4.37956
227 3L9W AMP 0.0001671 0.47703 4.37956
228 3CGD COA 0.001977 0.46739 4.37956
229 3CGD FAD 0.001977 0.46739 4.37956
230 3CGD NAD 0.001977 0.46739 4.37956
231 3RNM FAD 0.0007677 0.46324 4.37956
232 5MBX SP5 0.001324 0.46174 4.37956
233 5MBX FAD 0.001324 0.46174 4.37956
234 3L9W GSH 0.0003532 0.46006 4.37956
235 3TKY SAH 0.0001609 0.45379 4.37956
236 3CGB FAD 0.001061 0.45041 4.37956
237 3LAD FAD 0.001538 0.44877 4.37956
238 3T31 DCQ 0.00421 0.44022 4.37956
239 3T31 FAD 0.003904 0.44022 4.37956
240 2YY7 NAD 0.001214 0.44019 4.37956
241 4M52 FAD 0.002599 0.43863 4.37956
242 1XHL NDP 0.001506 0.43753 4.37956
243 3GWZ SAH 0.0004671 0.42089 4.37956
244 3GXO SAH 0.004666 0.42064 4.37956
245 1ZMD NAI 0.0007418 0.42016 4.37956
246 4P83 U5P 0.01803 0.40449 4.3956
247 1GZW GAL BGC 0.03882 0.40211 4.47761
248 4POO SAM 0.000004876 0.53055 4.5
249 1EDO NAP 0.001698 0.4353 4.5082
250 1XDS SAM 0.0002983 0.48042 4.54545
251 2DTX BMA 0.002373 0.43729 4.54545
252 2EJU SAH 0.0000001214 0.56816 4.74453
253 4GQB 0XU 0.000004475 0.5321 4.74453
254 5FA5 MTA 0.000005232 0.48868 4.74453
255 4Z24 FAD 0.0003051 0.48001 4.74453
256 5G3U FDA 0.0006645 0.46049 4.74453
257 2C7G ODP 0.001857 0.45502 4.74453
258 2C7G FAD 0.001932 0.45502 4.74453
259 1GPE FAD 0.00183 0.44834 4.74453
260 1X87 NAD 0.0004221 0.44818 4.74453
261 5G3U ITW 0.003746 0.43345 4.74453
262 1ORR NAD 0.002373 0.43033 4.74453
263 3GMB FAD 0.003837 0.42253 4.74453
264 2G2Y MLI 0.01587 0.41685 4.74453
265 1MXH DHF 0.01363 0.40278 4.74453
266 1MXH NAP 0.01374 0.40262 4.74453
267 1Z6Z NAP 0.008867 0.40195 4.74453
268 4ITU NAI 0.0003233 0.40325 4.83271
269 5CUQ NSC 0.000001602 0.5652 4.86891
270 2GAG NAD 0.0002848 0.47539 5.05051
271 2GAG FAD 0.001584 0.45115 5.05051
272 2GAG FOA 0.001584 0.45115 5.05051
273 5MGZ SAH 0.00004247 0.47639 5.08475
274 1NW5 SAM 0.0000128 0.4972 5.10949
275 1ZGA SAH 0.000004372 0.48902 5.10949
276 1KPG SAH 0.0003017 0.45225 5.10949
277 3AYI FAD 0.002288 0.44924 5.10949
278 3AYI HCI 0.002384 0.44924 5.10949
279 1G0N PHH 0.002024 0.44244 5.10949
280 1G0N NDP 0.001729 0.44225 5.10949
281 4AZT SAM 0.0008203 0.42136 5.10949
282 5L4S NAP 0.008871 0.40998 5.10949
283 5L4S 6KX 0.008871 0.40998 5.10949
284 3KL3 GCU 0.01215 0.40419 5.10949
285 5T2U NAP 0.002139 0.43228 5.24194
286 4JLS 3ZE 0.001508 0.47191 5.26316
287 5GT9 NAP 0.01042 0.40018 5.32319
288 1ZEM NAD 0.0009461 0.4388 5.34351
289 1G60 SAM 0.000001464 0.53408 5.38462
290 5JJR SAH 0.000001844 0.56193 5.47445
291 3TKA SAM 0.000003477 0.52598 5.47445
292 1MO9 FAD 0.002403 0.46394 5.47445
293 1XHC FAD 0.000508 0.46315 5.47445
294 1MO9 KPC 0.003023 0.45974 5.47445
295 2CDU FAD 0.0008085 0.45435 5.47445
296 1PS9 FAD 0.001604 0.44693 5.47445
297 4YAG NAI 0.003673 0.43194 5.47445
298 2B9W FAD 0.008107 0.42639 5.47445
299 4AZW SAM 0.0008739 0.42538 5.47445
300 1KEW NAD 0.01285 0.41425 5.47445
301 4PLG NAI 0.01058 0.40661 5.47445
302 1ZBQ NAD 0.009078 0.40397 5.47445
303 2CDU ADP 0.002284 0.4002 5.47445
304 3H8V ATP 0.0002717 0.44047 5.47945
305 2HMT NAI 0.0001716 0.46232 5.55556
306 4EMJ FAD 0.0006111 0.46325 5.60748
307 5XVQ SAH 0.0005439 0.43603 5.6338
308 4R6W SAH 0.00001339 0.52561 5.81395
309 4R6W PC 0.00005087 0.52456 5.81395
310 5DWQ SFG 0.000002558 0.5422 5.83942
311 5DX0 SFG 0.0000055 0.53057 5.83942
312 5DX1 SFG 0.000006082 0.52874 5.83942
313 5DX8 SFG 0.000007025 0.52171 5.83942
314 5DXA SFG 0.00001176 0.50166 5.83942
315 3SQP FAD 0.003814 0.47944 5.83942
316 5HSA FAS 0.001067 0.45478 5.83942
317 2RGO FAD 0.001301 0.44652 5.83942
318 5L95 AMP 0.0003526 0.44031 5.83942
319 2O07 MTA 0.0001587 0.43413 5.83942
320 3FPF TNA 0.000006517 0.42388 5.83942
321 3FPF MTA 0.000006517 0.42388 5.83942
322 2O07 SPD 0.0001897 0.42148 5.83942
323 2RGH FAD 0.01632 0.40121 5.83942
324 3H2B SAH 0.000008147 0.50404 5.91133
325 1JG3 ADN 0.00005115 0.49889 5.95745
326 1MZV AMP 0.00805 0.42174 5.95745
327 4QAR ADE 0.009997 0.40914 5.97015
328 5XVK SAH 0.002469 0.41645 5.98592
329 3FZG SAM 0.003186 0.42821 6
330 3LST SAH 0.0001217 0.49858 6.03448
331 2AG5 NAD 0.001748 0.43204 6.09756
332 4CQM NAP 0.003531 0.41902 6.14754
333 4EUE NAI 0.0002134 0.47398 6.20438
334 4CNK FAD 0.0005022 0.46583 6.20438
335 5JCM NAD 0.002116 0.45906 6.20438
336 5JCM FAD 0.002045 0.45906 6.20438
337 5JCM ISD 0.002116 0.45906 6.20438
338 2VVM FAD 0.0009488 0.45595 6.20438
339 1KPH SAH 0.0003827 0.44801 6.20438
340 2R4J 13P 0.002505 0.44745 6.20438
341 2Y6Q FAD 0.001818 0.43403 6.20438
342 2Y6Q I7T 0.00399 0.43403 6.20438
343 2YVF FAD 0.01025 0.42444 6.20438
344 2YVF NAD 0.01059 0.42444 6.20438
345 1V6A TRE 0.01283 0.421 6.20438
346 4GLL NAD 0.006261 0.41093 6.20438
347 1QZZ SAM 0.0007351 0.41081 6.20438
348 2NVK FAD 0.01632 0.40213 6.20438
349 4CCW VKC 0.04218 0.40101 6.20438
350 1IY8 NAD 0.001109 0.44188 6.36704
351 5JE0 SAH 0.000003312 0.54984 6.47773
352 5JE0 AZ8 0.000003312 0.54984 6.47773
353 3NUG NAD 0.0002656 0.46842 6.47773
354 1F3L SAH 0.00000458 0.52701 6.56934
355 4YNU LGC 0.00124 0.45873 6.56934
356 4YNU FAD 0.00102 0.45873 6.56934
357 4MIG G3F 0.002168 0.44775 6.56934
358 3QVP FAD 0.002099 0.44375 6.56934
359 1FL2 FAD 0.0156 0.40115 6.56934
360 5E1M PRO PRO LYS ARG ILE ALA 0.00001995 0.5214 6.639
361 5E1M SAH 0.00001995 0.5214 6.639
362 4FGC PQ0 0.006197 0.4387 6.66667
363 1L3I SAH 0.000002802 0.54497 6.77083
364 1H82 GZZ 0.001207 0.46827 6.93431
365 1H82 FAD 0.0009941 0.46827 6.93431
366 1BZL FAD 0.003446 0.46316 6.93431
367 1D4D FAD 0.0009597 0.45891 6.93431
368 5BUK FAD 0.002501 0.44131 6.93431
369 3IHG FAD 0.001369 0.43511 6.93431
370 2C31 TZD 0.02117 0.41559 6.93431
371 2C31 ADP 0.02062 0.41559 6.93431
372 1LSS NAD 0.00009584 0.46729 7.14286
373 3VSE SAH 0.000003617 0.47757 7.29927
374 5BR7 FAD 0.000999 0.47208 7.29927
375 1E1M FAD 0.00124 0.46222 7.29927
376 5BR7 FLC 0.001987 0.45822 7.29927
377 4XQC NAD 0.00321 0.43551 7.29927
378 2E5V FAD 0.005258 0.42593 7.29927
379 4XQC 13D 0.006527 0.42264 7.29927
380 1W8D NAP 0.002783 0.41597 7.29927
381 3O26 NDP 0.004496 0.41454 7.29927
382 1W6U NAP 0.003389 0.41241 7.29927
383 1W73 NAP 0.002836 0.4032 7.29927
384 4X9M FAD 0.00009666 0.49978 7.66423
385 4PNE SAH 0.00006114 0.48287 7.66423
386 3AD8 NAD 0.000221 0.4762 7.66423
387 3AD8 FAD 0.002486 0.45646 7.66423
388 3AD8 PYC 0.002486 0.45646 7.66423
389 3UCL CYH 0.003956 0.44636 7.66423
390 3UCL FAD 0.003956 0.44636 7.66423
391 3UCL NAP 0.004348 0.44636 7.66423
392 1TPY SAH 0.0004218 0.44627 7.66423
393 4RSL FAD 0.002859 0.43042 7.66423
394 1A27 NAP 0.002428 0.42595 7.66423
395 1I2B NAD 0.008509 0.42469 7.66423
396 3OID NDP 0.00253 0.42913 7.75194
397 4XUC 43G 0.000007117 0.54077 7.79817
398 4XUC SAM 0.000007117 0.54077 7.79817
399 2F5Z FAD 0.0009972 0.45817 7.8125
400 5ITV NAI 0.0002981 0.46627 7.84314
401 1KYZ SAH 0.00003426 0.47538 8.0292
402 1KNR FAD 0.001345 0.44925 8.0292
403 1JNR FAD 0.005805 0.44342 8.0292
404 2OBF F83 0.00358 0.43243 8.0292
405 2OBF SAH 0.00358 0.43243 8.0292
406 1KYZ FER 0.002431 0.42308 8.0292
407 2GZ3 NAP 0.01154 0.41483 8.0292
408 4D42 NAP 0.01392 0.4119 8.0292
409 4D42 W0I 0.01392 0.4119 8.0292
410 5KF6 NAD 0.008155 0.40598 8.0292
411 5EOW FAD 0.01162 0.40163 8.0292
412 1AE1 NAP 0.002124 0.43241 8.05861
413 2AE2 NAP 0.002477 0.43752 8.07692
414 2AE2 PTO 0.002477 0.43752 8.07692
415 2PX8 SAH 0.00001466 0.48787 8.17844
416 3T7S SAM 0.000015 0.48892 8.20895
417 1O97 FAD 0.006542 0.43067 8.33333
418 1O97 AMP 0.006542 0.43067 8.33333
419 2ZFU SAH 0.000123 0.46258 8.37209
420 3LKZ SFG 0.000001508 0.53324 8.39416
421 4YRY NAD 0.001904 0.4537 8.39416
422 4C3Y FAD 0.001138 0.45353 8.39416
423 4YRY FAD 0.001441 0.45003 8.39416
424 4C3Y ANB 0.001934 0.4482 8.39416
425 1NML CIT 0.009921 0.42632 8.39416
426 4J7U YTZ 0.01606 0.40333 8.39416
427 4J7U NAP 0.01606 0.40333 8.39416
428 2XVM SAH 0.00004152 0.45419 8.54271
429 4FN4 NAD 0.0004591 0.40504 8.66142
430 3PFG SAM 0.006773 0.44603 8.74525
431 3A25 SAM 0.000001154 0.57081 8.75912
432 5KMS NAD 0.00148 0.46191 8.75912
433 5TTJ FAD 0.0007049 0.46052 8.75912
434 3O03 NAP 0.0005509 0.44867 8.75912
435 5KMS FAD 0.003762 0.42521 8.75912
436 2IVD FAD 0.0001272 0.40339 8.75912
437 1I1N SAH 0.00002597 0.50627 8.84956
438 4HSU FAD 0.0005676 0.47013 8.87097
439 4GUT FAD 0.0006738 0.4688 8.87097
440 3PT9 SAH 0.00000001619 0.59962 9.12409
441 4RPL 3UC 0.000312 0.49936 9.12409
442 4RPL FAD 0.0003031 0.49769 9.12409
443 3MBI HSX 0.006496 0.43091 9.12409
444 3MQ2 SAH 0.0002927 0.43403 9.17431
445 2YVJ FAD 0.004837 0.42154 9.17431
446 1NFQ NAI 0.001126 0.44296 9.23077
447 4QED NAP 0.004255 0.41556 9.27419
448 1XTP SAI 0.00001004 0.49443 9.44882
449 4REP FAD 0.0008008 0.45808 9.48905
450 3JWH SAH 0.00001281 0.4637 9.67742
451 3GEG NAD 0.0005622 0.44993 9.7166
452 5ULP KB1 0.00000034 0.57862 9.85401
453 5HJM MTA 0.000003828 0.54185 9.85401
454 3GDN HBX 0.001563 0.45594 9.85401
455 3GDN FAD 0.001061 0.45594 9.85401
456 5MZI FYK 0.005322 0.43766 9.85401
457 5MZI FAD 0.005141 0.43766 9.85401
458 4OPC PGT 0.01401 0.4368 9.85401
459 4OPC FDA 0.01222 0.4368 9.85401
460 3BXO SAM 0.000003596 0.49025 10.0418
461 2VDV SAM 0.000001678 0.58541 10.1626
462 5MW4 5JU 0.00000239 0.57078 10.219
463 5THY SAH 0.0000008211 0.55116 10.219
464 5THZ SAH 0.000003281 0.53538 10.219
465 3QOX SAH 0.000009207 0.51686 10.219
466 3GD4 NAD 0.001549 0.47063 10.219
467 3GD4 FAD 0.0009575 0.47063 10.219
468 3CTY FAD 0.0008728 0.46177 10.219
469 2DKH FAD 0.001522 0.43865 10.219
470 2DKH 3HB 0.00221 0.43865 10.219
471 4J1Q NDP 0.006001 0.40649 10.219
472 5MPT SAH 0.000002784 0.51721 10.5839
473 4KRG SAH 0.00000372 0.50256 10.5839
474 5JWC FAD 0.004178 0.42209 10.5839
475 1UAY ADN 0.0002465 0.48428 10.7438
476 4J56 FAD 0.003581 0.43433 10.9489
477 2IV2 MGD 0.01288 0.40183 10.9489
478 2VL8 UDP 0.003623 0.40025 10.9489
479 2HNK SAH 0.000009349 0.50849 11.2971
480 1DL5 SAH 0.00000038 0.58141 11.3139
481 4MOP 2H5 0.001098 0.46377 11.3139
482 3KLJ FAD 0.0005114 0.45908 11.3139
483 1RYD GLC 0.01156 0.42633 11.3139
484 1XCL SAH 0.00001154 0.45256 11.4894
485 1BC5 SAH 0.004793 0.40453 11.5242
486 3EVG SAH 0.000002856 0.517 11.6788
487 5EB4 FAD 0.0009874 0.45518 11.6788
488 5LOG SAH 0.0000936 0.46257 12.0172
489 1G55 SAH 0.0000001234 0.60567 12.0438
490 5E8J SAH 0.000004202 0.5668 12.0438
491 2P41 SAH 0.00000362 0.54913 12.0438
492 5KVA SAM 0.000002578 0.53727 12.0438
493 5E9W SAH 0.000006123 0.47174 12.0438
494 2YX1 SFG 0.0000002366 0.52762 12.7737
495 3EVF SAH 0.00001815 0.42353 12.9964
496 3EVF GTA 0.00002149 0.40915 12.9964
497 5KOK SAH 0.00001501 0.4923 13.5036
498 3ICS FAD 0.0002925 0.47614 13.5036
499 3ICR FAD 0.0003145 0.4735 13.5036
500 5KOK S9T 0.0004055 0.46479 13.5036
501 3ICT FAD 0.0005958 0.46136 13.5036
502 5KOK R9T 0.001328 0.44121 13.5036
503 5UAV TFB 0.01012 0.40641 13.5036
504 5UAV NDP 0.01012 0.40641 13.5036
505 5K7U SAM 0.00008251 0.45916 13.7778
506 5E72 SAM 0.00000007604 0.60016 13.8686
507 3VYW SAM 0.0000009732 0.56084 13.8686
508 1E6E FAD 0.0004408 0.46584 14.0625
509 1P1C SAH 0.00002269 0.50066 14.0704
510 4NTD FAD 0.001418 0.44603 14.2336
511 1XKQ NDP 0.002239 0.43142 14.2336
512 5FA8 SAM 0.00001132 0.51315 14.2857
513 4PIO AVI 0.0005923 0.45633 14.5985
514 4PIO SAH 0.0006361 0.45633 14.5985
515 1R6D NAD 0.008163 0.42478 14.5985
516 1R6D DAU 0.008022 0.42437 14.5985
517 5IL1 SAM 0.00006468 0.46345 14.6226
518 1QAN SAH 0.0000000492 0.60793 14.7541
519 4NEC SAH 0.00005973 0.50703 14.7727
520 5JCA FAD 0.001108 0.45509 14.7887
521 5JCA NDP 0.002817 0.45119 14.7887
522 2PXX SAH 0.00003038 0.48181 15.3488
523 4OBW SAM 0.00003582 0.50565 15.9533
524 3HVJ 705 0.0000007187 0.58904 16.2896
525 1R18 SAH 0.000006943 0.51958 16.2996
526 5ODQ FAD 0.002983 0.43596 16.3043
527 4YUW S4M 0.0004309 0.50915 16.7883
528 4YUW 4JU 0.0004413 0.50915 16.7883
529 1RYI FAD 0.00202 0.44248 16.7883
530 5N5D SAM 0.000007322 0.50519 16.8142
531 1JQ3 AAT 0.00001005 0.44547 17.1533
532 3MB5 SAM 0.0000006979 0.55112 17.2549
533 3ELW SAM 0.00001644 0.40369 17.5182
534 4TQG NDP 0.0003241 0.46164 18.2482
535 5DNK SAH 0.00002845 0.44301 20.8029
536 3UOY FAD 0.003688 0.44909 21.5328
537 3UOY NAP 0.003688 0.44909 21.5328
538 3A27 SAM 0.0000002329 0.60118 22.0588
539 2PWY SAH 0.0000001912 0.58641 22.8682
540 5FTW SAH 0.001871 0.41572 24.6094
541 4DMG SAM 0.0003254 0.48417 24.8175
542 4II2 ATP 0.00093 0.42875 28.9157
543 1SQF SAM 0.00000000006317 0.75698 47.4453
Pocket No.: 2; Query (leader) PDB : 3A4T; Ligand: SFG; Similar sites found: 15
This union binding pocket(no: 2) in the query (biounit: 3a4t.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1DCP HBI 0.02567 0.4033 None
2 3ZNN FAD 0.003132 0.44298 4.0146
3 3ZNN 4WL 0.003132 0.44298 4.0146
4 3WGT FAD 0.004174 0.43096 4.0146
5 3WGT QSC 0.004362 0.43096 4.0146
6 4TM3 FAD 0.001778 0.46126 4.37956
7 1E5Q NDP 0.001305 0.40007 4.37956
8 1GR0 NAD 0.01075 0.40037 4.74453
9 4DS0 A2G GAL NAG FUC 0.02657 0.41078 4.90798
10 5TH5 MET 0.03193 0.40375 5.70342
11 2EWM NAD 0.0005897 0.40239 6.4257
12 2OKK ABU 0.04398 0.40787 7.66423
13 3ML1 MGD 0.03648 0.40145 8.88889
14 3JUC PCA 0.02627 0.40386 9.15033
15 2WPB ZZI 0.02745 0.40484 10.9489
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