Receptor
PDB id Resolution Class Description Source Keywords
3A2B 2.3 Å EC: 2.3.1.50 CRYSTAL STRUCTURE OF SERINE PALMITOYLTRANSFERASE FROM SPHING MULTIVORUM WITH SUBSTRATE L-SERINE SPHINGOBACTERIUM MULTIVORUM VITAMIN B6-DEPENDENT ENZYME FOLD TYPE I ACYLTRANSFERASE PYPHOSPHATE TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO THE ENZYMATIC MECHANISM OF PALMITOYLTRANSFERASE FROM SPHINGOBACTERIUM MULTIVOR J.BIOCHEM. V. 146 549 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SER PLP A:401;
 Valid;
 none;
 submit data
331.197 n/a P(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3A2B 2.3 Å EC: 2.3.1.50 CRYSTAL STRUCTURE OF SERINE PALMITOYLTRANSFERASE FROM SPHING MULTIVORUM WITH SUBSTRATE L-SERINE SPHINGOBACTERIUM MULTIVORUM VITAMIN B6-DEPENDENT ENZYME FOLD TYPE I ACYLTRANSFERASE PYPHOSPHATE TRANSFERASE
Ref.: STRUCTURAL INSIGHTS INTO THE ENZYMATIC MECHANISM OF PALMITOYLTRANSFERASE FROM SPHINGOBACTERIUM MULTIVOR J.BIOCHEM. V. 146 549 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3A2B - SER PLP n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3A2B - SER PLP n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1FC4 - AKB PLP n/a n/a
2 3A2B - SER PLP n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SER PLP; Similar ligands found: 46
No: Ligand ECFP6 Tc MDL keys Tc
1 SER PLP 1 1
2 PLP ALO 0.704225 0.943396
3 PLP PHE 0.701299 0.907407
4 PLP 999 0.694444 0.943396
5 KOU 0.671429 0.910714
6 PLP PVH 0.646341 0.78125
7 GLY PLP 0.633803 0.888889
8 PLP ABU 0.584416 0.875
9 PL6 0.571429 0.827586
10 PLP MYB 0.564706 0.731343
11 PL5 0.548781 0.786885
12 F0G 0.546667 0.839286
13 PLP PUT 0.538462 0.8
14 EPC 0.534247 0.803571
15 PUS 0.53012 0.746269
16 P70 0.53012 0.842105
17 EQJ 0.529412 0.793651
18 5DK 0.529412 0.793651
19 6DF 0.5125 0.758621
20 FEJ 0.506173 0.827586
21 PLP 142 0.494624 0.78125
22 EVM 0.493671 0.928571
23 4LM 0.493506 0.79661
24 0JO 0.493506 0.813559
25 Q0P 0.483516 0.774194
26 PLT 0.473118 0.774194
27 FEV 0.4625 0.783333
28 Z98 0.452381 0.790323
29 EXT 0.448718 0.810345
30 ASP PLP 0.440476 0.824561
31 HCP 0.439024 0.754098
32 MPM 0.432099 0.793103
33 PLP SER 0.432099 0.786885
34 PLP 0.422535 0.781818
35 P3D 0.421687 0.746032
36 P89 0.417582 0.701493
37 PLP CYS 0.416667 0.790323
38 PZP 0.416667 0.754386
39 FOO 0.4125 0.793103
40 PLP 2TL 0.411765 0.803279
41 SEP PLP 0.406977 0.833333
42 PLP BH2 0.406977 0.803279
43 PLP PMP 0.405405 0.762712
44 LEU PLP 0.402299 0.777778
45 AN7 0.4 0.754386
46 PLP 2KZ 0.4 0.786885
Similar Ligands (3D)
Ligand no: 1; Ligand: SER PLP; Similar ligands found: 41
No: Ligand Similarity coefficient
1 PLS 0.9965
2 P1T 0.9672
3 2BO 0.9592
4 C6P 0.9590
5 PLG 0.9582
6 PDA 0.9544
7 2BK 0.9505
8 TLP 0.9495
9 CKT 0.9431
10 PLI 0.9405
11 PP3 0.9405
12 PDD 0.9355
13 PLP GLY 0.9309
14 5PA 0.9300
15 IN5 0.9298
16 DCS 0.9266
17 7TS 0.9230
18 PLP MET 0.9135
19 MET PLP 0.9132
20 L7N 0.9097
21 IK2 0.9085
22 LCS 0.9073
23 PPD 0.9017
24 PM9 0.8996
25 PLP 2ML 0.8993
26 PY5 0.8964
27 PMH 0.8946
28 ILP 0.8939
29 PLA 0.8936
30 KET 0.8897
31 7XF 0.8851
32 OJQ 0.8846
33 3QP 0.8843
34 3LM 0.8787
35 PLP 0A0 0.8787
36 PGU 0.8744
37 07U 0.8737
38 PPE 0.8704
39 8JF 0.8696
40 PLP SEP 0.8636
41 P19 0.8561
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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