Receptor
PDB id Resolution Class Description Source Keywords
2yc0 2.15 Å EC: 1.14.11.16 FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH R-2-HYDROXYGLU HOMO SAPIENS OXIDOREDUCTASE DIOXYGENASE METAL-BINDING TRANSCRIPTION HLOOP-HELIX-BETA DSBH FACIAL TRIAD ASPARAGINYL/ASPARTYL HYDROXYLASE TRANSCRIPTION AND EPIGENETIC REGULATION SIGNADEVELOPMENT CELL STRUCTURE ANKYRIN REPEAT DOMAIN ARD BEHYDROXYLATION TRANSCRIPTION ACTIVATOR/INHIBITOR PHOSPHORYS-NITROSYLATION
Ref.: THE ONCOMETABOLITE 2-HYDROXYGLUTARATE INHIBITS HISTONE LYSINE DEMETHYLASES. EMBO REP. V. 12 463 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
2HG A:601;
Valid;
none;
ic50 = 1500 uM
148.114 C5 H8 O5 C(CC(...
FE2 A:501;
Part of Protein;
none;
submit data
55.845 Fe [Fe+2...
GOL A:602;
A:603;
A:604;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SO4 A:901;
A:902;
A:904;
A:905;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2WA4 2.5 Å EC: 1.14.11.16 FACTOR INHIBITING HIF-1 ALPHA WITH N,3-DIHYDROXYBENZAMIDE HOMO SAPIENS HYDROXYLASE DIOXYGENASE TRANSCRIPTION OXIDOREDUCTASE TRANSCRIPTION ACTIVATOR/INHIBITOR HYPOXIA
Ref.: STRUCTURAL BASIS FOR BINDING OF CYCLIC 2-OXOGLUTARATE ANALOGUES TO FACTOR-INHIBITING HYPOXIA-INDUCIBLE FACTOR. BIOORG.MED.CHEM.LETT. V. 20 6125 2010
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 2W0X ic50 = 625 uM PD2 C7 H5 N O4 c1cnc(cc1C....
2 1MZF - AKG C5 H6 O5 C(CC(=O)O)....
3 2WA3 ic50 = 1 mM A29 C8 H6 O4 c1cc(cc(c1....
4 2CGN - SIN C4 H6 O4 C(CC(=O)O)....
5 2WA4 ic50 = 18 uM 069 C7 H7 N O3 c1cc(cc(c1....
6 4AI8 ic50 > 100 uM DZA C6 H12 N2 O3 CN(C)NC(=O....
7 1MZE - TAR C4 H6 O6 C(C(C(=O)O....
8 2YDE ic50 = 189 uM S2G C5 H8 O5 C(CC(=O)O)....
9 2YC0 ic50 = 1500 uM 2HG C5 H8 O5 C(CC(=O)O)....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2W0X ic50 = 625 uM PD2 C7 H5 N O4 c1cnc(cc1C....
2 1MZF - AKG C5 H6 O5 C(CC(=O)O)....
3 2WA3 ic50 = 1 mM A29 C8 H6 O4 c1cc(cc(c1....
4 2CGN - SIN C4 H6 O4 C(CC(=O)O)....
5 2WA4 ic50 = 18 uM 069 C7 H7 N O3 c1cc(cc(c1....
6 4AI8 ic50 > 100 uM DZA C6 H12 N2 O3 CN(C)NC(=O....
7 1MZE - TAR C4 H6 O6 C(C(C(=O)O....
8 2YDE ic50 = 189 uM S2G C5 H8 O5 C(CC(=O)O)....
9 2YC0 ic50 = 1500 uM 2HG C5 H8 O5 C(CC(=O)O)....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2W0X ic50 = 625 uM PD2 C7 H5 N O4 c1cnc(cc1C....
2 1MZF - AKG C5 H6 O5 C(CC(=O)O)....
3 2WA3 ic50 = 1 mM A29 C8 H6 O4 c1cc(cc(c1....
4 2CGN - SIN C4 H6 O4 C(CC(=O)O)....
5 2WA4 ic50 = 18 uM 069 C7 H7 N O3 c1cc(cc(c1....
6 4AI8 ic50 > 100 uM DZA C6 H12 N2 O3 CN(C)NC(=O....
7 1MZE - TAR C4 H6 O6 C(C(C(=O)O....
8 2YDE ic50 = 189 uM S2G C5 H8 O5 C(CC(=O)O)....
9 2YC0 ic50 = 1500 uM 2HG C5 H8 O5 C(CC(=O)O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 2HG; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 2HG 1 1
2 S2G 1 1
3 DMR 0.461538 0.809524
4 MLT 0.461538 0.809524
5 LMR 0.461538 0.809524
6 2RH 0.444444 0.652174
7 DGY 0.44 0.666667
8 GGL 0.433333 0.653846
9 DGL 0.433333 0.653846
10 GLU 0.433333 0.653846
11 HOC 0.411765 0.62963
12 HCT 0.40625 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2WA4; Ligand: 069; Similar sites found: 377
This union binding pocket(no: 1) in the query (biounit: 2wa4.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
1 2XUM OGA 0.000000000005129 0.69838
2 2XUM OGA 0.000000000005129 0.69838
3 4B7E OGA 0.00000000006502 0.68814
4 4GJY OGA 0.0000000002179 0.643
5 3PDQ KC6 0.000009406 0.59926
6 4ASK K0I 0.00000319 0.58012
7 4ASK K0I 0.000003767 0.57667
8 3PDQ KC6 0.00002218 0.56493
9 4IE6 UN9 0.00001194 0.56137
10 4BQY FNT 0.000004685 0.55202
11 3AVS OGA 0.000001847 0.54966
12 1UNB AKG 0.00003928 0.53807
13 1UNB PN1 0.00004635 0.53807
14 2GC0 PAN 0.00001596 0.53664
15 3MPB FRU 0.00001272 0.53535
16 2RDQ AKG 0.00002748 0.53315
17 4QXB OGA 0.00000398 0.52652
18 4LIT AKG 0.000001287 0.52594
19 4QXB OGA 0.000008587 0.52237
20 3H7J PPY 0.00003034 0.51794
21 1J3R 6PG 0.00001652 0.5176
22 4IGQ THR M3L GLN 0.0000466 0.51746
23 3AVR OGA 0.000002878 0.51603
24 3OPT AKG 0.000004281 0.51381
25 2Q8E OGA 0.000007232 0.50568
26 1LRH NLA 0.0000338 0.50437
27 1GQG DCD 0.0001165 0.50333
28 2Q8C AKG 0.000003166 0.50323
29 4HON AKG 0.000003136 0.50253
30 1ODM ASV 0.000165 0.50221
31 3PUA OGA 0.0000093 0.50199
32 2Q8E OGA 0.00001009 0.50095
33 4J25 OGA 0.00002716 0.50036
34 1GQG DCD 0.0001498 0.50027
35 3HQR OGA 0.00006418 0.49997
36 4HON AKG 0.000003832 0.49979
37 2OS2 OGA 0.00001135 0.49883
38 2OS2 OGA 0.00001156 0.49857
39 3H7J PPY 0.00008271 0.49786
40 2JIG PD2 0.00003029 0.49765
41 2FCU AKG 0.000006522 0.49744
42 2XK9 XK9 0.0004186 0.49673
43 2PXJ OGA 0.00001225 0.49652
44 2PXJ OGA 0.00001437 0.49369
45 2YBP 2HG 0.0000158 0.49343
46 2YBP 2HG 0.00001725 0.49227
47 2FCU AKG 0.000008946 0.49219
48 4QM9 CYS 0.00001838 0.49005
49 3N9Q OGA 0.000006198 0.4893
50 3N9O OGA 0.000007636 0.48654
51 1QIN GIP 0.0005692 0.48591
52 3N9P OGA 0.000008393 0.48458
53 3PQB VGP 0.0003092 0.48319
54 3PQB VGP 0.0003247 0.48218
55 4BG1 OGA 0.000346 0.48087
56 4BG1 IVL 0.000346 0.48087
57 4J25 OGA 0.00002367 0.4807
58 1DZK PRZ 0.000231 0.47991
59 3E8N ATP 0.001394 0.47971
60 3E8N VRA 0.001394 0.47971
61 3E8N VRA 0.001394 0.47971
62 3E8N ATP 0.001394 0.47971
63 1OLM VTQ 0.0005772 0.47942
64 4J25 OGA 0.00005234 0.4791
65 1ZB6 GST 0.0006863 0.47892
66 4IEU 2CO 0.000035 0.47844
67 3PFG TLO 0.001398 0.47755
68 3PFG SAM 0.001398 0.47755
69 1ZB6 DIN 0.0007173 0.47643
70 3FW4 CAQ 0.0004361 0.47609
71 4J25 OGA 0.0000343 0.47537
72 4J25 OGA 0.00003461 0.47509
73 4CCK OGA 0.00001288 0.47455
74 2ET1 GLV 0.00004108 0.4745
75 3RGA LSB 0.0003089 0.47405
76 4J25 OGA 0.00003786 0.47369
77 4Q0P 0MK 0.001464 0.47318
78 3FW9 SLX 0.0004152 0.47281
79 1YP6 PRZ 0.0003749 0.47258
80 2Q8C AKG 0.000008039 0.47201
81 3FW4 CAQ 0.0006065 0.47125
82 1FM4 DXC 0.002465 0.47084
83 3ACL 3F1 0.0003661 0.47063
84 1T27 PCW 0.002006 0.4706
85 4CCO OGA 0.0000807 0.47054
86 4DE9 VTP 0.001123 0.46989
87 4J25 OGA 0.00005297 0.46868
88 3KV4 OGA 0.00005736 0.46789
89 1GT4 UNA 0.0004337 0.46721
90 3E2M E2M 0.0009163 0.4663
91 1ZZ7 S0H 0.0001272 0.46571
92 1DRY AKG 0.00111 0.46559
93 1DRY AAG 0.00111 0.46559
94 3Q8G PEE 0.003857 0.46499
95 1OLM VTQ 0.001083 0.46449
96 4IGQ OGA 0.000002634 0.46433
97 1DZK PRZ 0.0004557 0.46368
98 1GP6 DH2 0.001074 0.46297
99 1GP6 SIN 0.001074 0.46297
100 1GP6 QUE 0.001164 0.46297
101 4CCN OGA 0.00003086 0.46262
102 3H9A PPY 0.0001515 0.46224
103 1N5S ADL 0.0006074 0.46042
104 1OS7 AKG 0.000862 0.46001
105 1OS7 TAU 0.000862 0.46001
106 3PUR 2HG 0.00008497 0.45955
107 4J25 OGA 0.0002526 0.45904
108 4BXF AKG 0.00008891 0.45891
109 1LRH NLA 0.0002556 0.45857
110 3E2M E2M 0.001595 0.45793
111 3W21 AKG 0.00001535 0.4573
112 2FW4 HIS 0.004153 0.45639
113 4KNM E1E 0.0009333 0.45627
114 3KV5 OGA 0.00001641 0.45543
115 3KV5 OGA 0.00001641 0.45543
116 1EWF PC1 0.003651 0.45529
117 3PUR 2HG 0.0001063 0.45501
118 4WHZ 3NL 0.003537 0.45493
119 3E2M E2M 0.006224 0.45488
120 1OS7 TAU 0.001223 0.4548
121 1OS7 AKG 0.001223 0.4548
122 3VQ2 LP4 LP5 MYR DAO 0.00422 0.45411
123 4P7X AKG 0.0009459 0.4538
124 4P7X YCP 0.0009459 0.4538
125 4OCT AKG 0.0004562 0.45329
126 3E85 BSU 0.003928 0.45262
127 4IAW LIZ 0.0005069 0.45241
128 4KNM E1E 0.001273 0.45199
129 2X32 OTP 0.005499 0.45104
130 3MTX PGT 0.002887 0.45103
131 3QP8 HL0 0.001101 0.45071
132 3T4V MD3 0.000189 0.45023
133 2X34 UQ8 0.005709 0.4502
134 4QM9 CYS 0.00009424 0.44959
135 3D72 FAD 0.002917 0.44946
136 3NNF AKG 0.00006178 0.44901
137 2X32 OTP 0.006286 0.44893
138 4OJ8 AKG 0.00008314 0.4482
139 2X34 UQ8 0.006799 0.44718
140 4N1T 2GD 0.002088 0.44558
141 4OPC PGT 0.0251 0.44488
142 4OPC FDA 0.02199 0.44488
143 3P7N FMN 0.001659 0.44452
144 2VFT SOR 0.0007357 0.44399
145 3GBG PAM 0.00123 0.44379
146 1IF7 SBR 0.01987 0.44377
147 3IS2 FAD 0.003349 0.44371
148 4MP8 MLI 0.005815 0.44294
149 4MP8 NAD 0.005815 0.44294
150 4O9G T46 0.001134 0.44286
151 2FW4 HIS 0.007324 0.44281
152 4EIP FAD 0.008534 0.4412
153 2ARC ARA 0.0006461 0.44116
154 4P42 PEE 0.003054 0.44106
155 4GGZ BTN 0.0008936 0.44082
156 3SAO NKN 0.00143 0.44076
157 3QP8 HL0 0.001628 0.44053
158 3SCH TB6 0.0001555 0.43991
159 4OCT AKG 0.001066 0.43966
160 4PSB GA3 0.005655 0.43903
161 4JZR 4JR 0.0006593 0.43835
162 1Y0G 8PP 0.008692 0.43806
163 1Y0G 8PP 0.008788 0.43782
164 2PR5 FMN 0.002305 0.4378
165 2PR5 FMN 0.002305 0.4378
166 3W68 VIV 0.00304 0.43778
167 3W68 VIV 0.00304 0.43778
168 3W68 VIV 0.003057 0.43766
169 2GJ5 VD3 0.003967 0.43714
170 1MDC PLM 0.003146 0.43707
171 2Z6C FMN 0.002452 0.43654
172 3HX3 RET 0.002294 0.43581
173 2IUW AKG 0.001071 0.43571
174 1VA6 ADP 0.00669 0.43538
175 1VA6 P2S 0.007461 0.4353
176 2A1L PCW 0.01026 0.43529
177 2E56 MYR 0.005761 0.43488
178 1NYW DAU 0.002669 0.4348
179 2IFB PLM 0.003517 0.43475
180 2XXP DSL 0.02161 0.43401
181 2WT2 GAL NAG GAL NAG GAL NAG 0.004663 0.43373
182 3S7O LBV 0.006479 0.43363
183 1U0A BGC BGC BGC BGC 0.0023 0.43356
184 2RFZ CTR 0.003728 0.43354
185 3IX8 TX3 0.00492 0.4326
186 3FW3 ETS 0.002995 0.43245
187 2ZYI STE 0.004665 0.43217
188 2YG2 S1P 0.004099 0.43157
189 4QDC ASD 0.00255 0.43147
190 4M26 SIN 0.005339 0.43087
191 4M26 ZZU 0.005339 0.43087
192 4IJP 1EH 0.00359 0.43069
193 3T7A ADP 0.01163 0.43065
194 1LFO OLA 0.00328 0.43059
195 4LBK GAL NAG GAL BGC 0.002697 0.43034
196 3H9A PPY 0.0005107 0.43
197 2XMY CDK 0.01782 0.42938
198 4QDF 30Q 0.002849 0.42923
199 3T50 FMN 0.003561 0.42891
200 3T50 FMN 0.003561 0.42891
201 1VA6 P2S 0.01003 0.42884
202 2P7Q GG6 0.001191 0.42884
203 3BXO UPP 0.002923 0.42872
204 3WG3 A2G GAL NAG FUC 0.0005283 0.42808
205 1ZM1 BGC BGC BGC 0.003062 0.42778
206 4QA8 PJZ 0.005604 0.42672
207 2ZA0 MGI 0.007043 0.42649
208 3OYW TDG 0.001077 0.42645
209 4BJZ P3A 0.03432 0.42475
210 4BJZ FAD 0.03432 0.42475
211 3RWP ABQ 0.04146 0.42467
212 3RWP ABQ 0.04146 0.42467
213 1N9L FMN 0.004582 0.42376
214 1N9L FMN 0.004582 0.42376
215 1N9L FMN 0.004582 0.42376
216 3WDX BGC BGC GLC 0.005703 0.42297
217 2PUL ACP 0.0039 0.42289
218 2PUL ACP 0.0039 0.42289
219 4K3H 1OM 0.005262 0.42282
220 1UU6 BGC BGC BGC BGC 0.007993 0.42236
221 3WG3 A2G GAL NAG FUC 0.001819 0.42228
222 4K3H 1OM 0.005403 0.42228
223 4EIP K2C 0.02142 0.42213
224 4EIP FAD 0.02142 0.42213
225 1FDQ HXA 0.005989 0.42196
226 1QY1 PRZ 0.0005487 0.42186
227 1QY1 PRZ 0.0005487 0.42186
228 2RKV ZBA 0.0146 0.42167
229 2RKV COA 0.01258 0.42167
230 1RM0 NAI 0.02128 0.42148
231 4BJ8 BTN 0.004238 0.42122
232 4K3H 1OM 0.005806 0.4208
233 2Y6Q I7T 0.02287 0.42065
234 2WBQ ZZU 0.00699 0.42047
235 2NNQ T4B 0.0156 0.4202
236 1LN1 DLP 0.0128 0.42014
237 3T50 FMN 0.005477 0.4201
238 2Y6Q I7T 0.02352 0.42002
239 4NPL AKG 0.001224 0.41999
240 1WUB OTP 0.02009 0.41938
241 2Y6Q I7T 0.02434 0.41924
242 3SAO NKN 0.002592 0.41922
243 3KFF ZBT 0.001401 0.41906
244 3KFF XBT 0.001401 0.41906
245 1Y9Q MED 0.000536 0.4189
246 2Y6Q I7T 0.0248 0.41881
247 3IX8 TX3 0.008888 0.41862
248 3NKT 1HN 0.001443 0.4177
249 1NX4 AKG 0.001213 0.4177
250 3ZXE PGZ 0.001697 0.41759
251 2YG2 FLC 0.01009 0.41744
252 1DMY AZM 0.003169 0.41743
253 4ANW O92 0.01374 0.41742
254 2Z77 HE7 0.00882 0.41724
255 2Z77 HE7 0.00882 0.41724
256 2Z77 HE7 0.00882 0.41724
257 2YNE YNE 0.04227 0.41707
258 2YNE NHW 0.04227 0.41707
259 2Y88 2ER 0.01722 0.417
260 3GC8 B45 0.008273 0.41696
261 4BJ8 BTN 0.005236 0.41694
262 1RM0 D6P 0.02897 0.4168
263 4O2C ACE SER HIS VAL ALA VAL GLU ASN ALA LEU 0.04922 0.41666
264 2WPU KYT 0.008053 0.41583
265 2PYW ADP 0.007448 0.41567
266 3AGC RCC 0.01174 0.41564
267 4K3H 1OM 0.007528 0.41545
268 4NPL AKG 0.001709 0.41545
269 3OZ2 OZ2 0.01683 0.41533
270 4BJ8 BTN 0.005679 0.4153
271 3KAL ADP 0.01606 0.41522
272 2YAK OSV 0.01384 0.41479
273 2F01 BTQ 0.04687 0.41463
274 2F01 BTN 0.04687 0.41463
275 3MTX PGT 0.01937 0.41441
276 1ZM1 BGC BGC BGC 0.005994 0.41421
277 1TT8 PHB 0.01184 0.41406
278 2FB3 GTP 0.01445 0.41385
279 3ZXE PGZ 0.0007479 0.41384
280 3AMN CBK 0.01213 0.41353
281 3AMN CBI 0.01213 0.41353
282 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.03909 0.41341
283 2JDR L20 0.03909 0.41341
284 3EW2 BTN 0.003781 0.4132
285 1OGZ EQU 0.005049 0.41312
286 1R5L VIV 0.01183 0.4126
287 3A7R LAQ 0.02114 0.41249
288 3EW2 BTN 0.003851 0.41241
289 3M3R BCD 0.02431 0.41237
290 1IS3 LAT 0.0002865 0.41171
291 1EPB REA 0.002954 0.41159
292 4JNJ BTN 0.006175 0.41142
293 1OBD ATP 0.005499 0.41142
294 4CQE CQE 0.01007 0.41119
295 3STK PLM 0.02043 0.4111
296 2XN5 FUN 0.004075 0.4109
297 1QFT HSM 0.007911 0.41063
298 3LVW GSH 0.02305 0.41058
299 1FO0 ILE ASN PHE ASP PHE ASN THR ILE 0.02316 0.41048
300 3ORQ ADP 0.009667 0.41029
301 4J7Q B7N 0.02247 0.4101
302 1OIK C26 0.007379 0.41
303 3EKK GS2 0.01171 0.40971
304 3T2W BTN 0.004571 0.40963
305 1SJD NPG 0.01367 0.40956
306 3W8X FTK 0.006207 0.40901
307 4GCZ FMN 0.009622 0.40856
308 2RG0 CTT 0.01778 0.40812
309 4BCS BTN 0.008129 0.40804
310 3GC8 B45 0.01186 0.4078
311 1VA6 ADP 0.02277 0.40762
312 4BX7 B4F 0.01715 0.40757
313 4BVA T3 0.03031 0.40746
314 2WCV FUC 0.005603 0.40723
315 2CM4 RCL 0.01224 0.40715
316 3VV1 GAL FUC 0.0001704 0.40709
317 4F4P 0SB 0.03493 0.40696
318 4IJP 1EH 0.01148 0.40675
319 4J36 1HR 0.03812 0.40666
320 4JNJ BTN 0.007839 0.40663
321 1WBP ADP 0.003616 0.40651
322 3SLS 77D 0.009688 0.4065
323 3JRS A8S 0.01266 0.40644
324 3IU9 T07 0.03046 0.4064
325 3IU9 T07 0.03046 0.4064
326 1PN0 FAD 0.04452 0.40621
327 2ZHL NAG GAL GAL NAG 0.00577 0.40619
328 2FLI DX5 0.01308 0.40576
329 4R38 RBF 0.01207 0.40572
330 1OIK AKG 0.001153 0.40543
331 3EW2 BTN 0.004004 0.40529
332 1OGX EQU 0.008409 0.40521
333 1OIJ AKG 0.0006767 0.40513
334 2C1Q BTN 0.01051 0.40485
335 4O1P ANP 0.01056 0.40474
336 2FLI DX5 0.01267 0.40472
337 2YG2 S1P 0.01275 0.40457
338 3AJH BL3 0.01171 0.40454
339 2C49 ADN 0.01079 0.4043
340 2RFN AM7 0.0142 0.40406
341 2GQS C2R 0.008952 0.40396
342 2X4Z X4Z 0.0284 0.40389
343 4M1U A2G MBG 0.000254 0.40381
344 3LXK MI1 0.02085 0.40341
345 2HKA C3S 0.01359 0.40326
346 1YKD CMP 0.01141 0.40316
347 4NG2 OHN 0.01856 0.4031
348 1Y52 BTN 0.04155 0.40304
349 3MF2 AMP 0.01615 0.403
350 1QXW M1C 0.01264 0.40296
351 4JVF 17X 0.0268 0.40294
352 1W2D 4IP 0.02004 0.40289
353 1XI9 PLP 0.004778 0.4028
354 1XI9 PLP 0.004778 0.4028
355 1KJM ALA GLN PHE SER ALA SER ALA SER ARG 0.02573 0.40266
356 4J7Q B7N 0.02038 0.40253
357 4POW OP1 0.01653 0.40251
358 2AGC DAO 0.004675 0.40251
359 4O1P ANP 0.01071 0.40246
360 1YFX 4AA 0.004418 0.40223
361 4R38 RBF 0.01429 0.40223
362 4R38 RBF 0.01429 0.40223
363 4V24 GYR 0.0198 0.40173
364 4JNJ BTN 0.01 0.40173
365 4JNJ BTN 0.01 0.40173
366 4J7Q B7N 0.02151 0.40138
367 4NAO AKG 0.0006192 0.40132
368 4QCK ASD 0.01036 0.40102
369 3QP6 HL6 0.01046 0.40082
370 3B00 16A 0.009364 0.4008
371 4C2V YJA 0.02694 0.40045
372 4R38 RBF 0.01562 0.40038
373 4R38 RBF 0.01562 0.40038
374 4V24 GYR 0.03016 0.40037
375 4AZW ATP 0.01565 0.40034
376 3QP4 HL0 0.0119 0.40032
377 1C1L GAL BGC 0.0007544 0.40031
Pocket No.: 2; Query (leader) PDB : 2WA4; Ligand: 069; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2wa4.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc)
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