Receptor
PDB id Resolution Class Description Source Keywords
2x00 2.4 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF A-ACHBP IN COMPLEX WITH GYMNODIMINE A APLYSIA CALIFORNICA RECEPTOR PHYCOTOXIN TOXIN ACETYLCHOLINE BINDING PROTEIN
Ref.: STRUCTURAL DETERMINANTS IN PHYCOTOXINS AND ACHBP CONFERRING HIGH AFFINITY BINDING AND NICOTINIC ACHR ANTAGONISM. PROC.NATL.ACAD.SCI.USA V. 107 6076 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GYN A:301;
B:301;
C:301;
D:301;
E:301;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
Kd = 0.0047 nM
509.72 C32 H47 N O4 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2X00 2.4 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF A-ACHBP IN COMPLEX WITH GYMNODIMINE A APLYSIA CALIFORNICA RECEPTOR PHYCOTOXIN TOXIN ACETYLCHOLINE BINDING PROTEIN
Ref.: STRUCTURAL DETERMINANTS IN PHYCOTOXINS AND ACHBP CONFERRING HIGH AFFINITY BINDING AND NICOTINIC ACHR ANTAGONISM. PROC.NATL.ACAD.SCI.USA V. 107 6076 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 289 families.
1 2X00 Kd = 0.0047 nM GYN C32 H47 N O4 C[C@@H]1C[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 214 families.
1 2X00 Kd = 0.0047 nM GYN C32 H47 N O4 C[C@@H]1C[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 2X00 Kd = 0.0047 nM GYN C32 H47 N O4 C[C@@H]1C[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GYN; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 GYN 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: GYN; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2X00; Ligand: GYN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2x00.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2X00; Ligand: GYN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2x00.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2X00; Ligand: GYN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2x00.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2X00; Ligand: GYN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2x00.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 2X00; Ligand: GYN; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2x00.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback