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Receptor
PDB id Resolution Class Description Source Keywords
2q2y 2.5 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 1 HOMO SAPIENS KSP KSP-INHIBITOR COMPLEX CELL CYCLE
Ref.: KINESIN SPINDLE PROTEIN (KSP) INHIBITORS. PART 8: DESIGN AND SYNTHESIS OF 1,4-DIARYL-4,5-DIHYDROPYRAZOLES AS POTENT INHIBITORS OF THE MITOTIC KINESIN KSP. BIOORG.MED.CHEM.LETT. V. 17 5677 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:601;
B:602;
Valid;
Valid;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MG A:603;
B:604;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
MKR A:604;
B:605;
Valid;
Valid;
none;
none;
ic50 = 1.6 nM
478.558 C27 H31 F N4 O3 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2Q2Y 2.5 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF KSP IN COMPLEX WITH INHIBITOR 1 HOMO SAPIENS KSP KSP-INHIBITOR COMPLEX CELL CYCLE
Ref.: KINESIN SPINDLE PROTEIN (KSP) INHIBITORS. PART 8: DESIGN AND SYNTHESIS OF 1,4-DIARYL-4,5-DIHYDROPYRAZOLES AS POTENT INHIBITORS OF THE MITOTIC KINESIN KSP. BIOORG.MED.CHEM.LETT. V. 17 5677 2007
Members (26)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 65 families.
1 2UYM ic50 = 3.1 uM K03 C20 H26 N2 O2 S2 CCN(CC)C(=....
2 3L9H ic50 = 8 nM EMQ C25 H31 F3 N4 O2 CN(C)CCNC(....
3 1Q0B ic50 = 7 uM NAT C14 H16 N2 O3 S CCOC(=O)C1....
4 2FME ic50 = 104 nM 3QC C20 H24 N2 O2 Cc1ccc2c(c....
5 2FL6 ic50 = 38 nM N5T C19 H18 F2 N2 O CN(C)C(=O)....
6 4B7B - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
7 2X2R ic50 = 549 nM X2O C20 H25 N O2 S CC[C@@H](C....
8 2Q2Y ic50 = 1.6 nM MKR C27 H31 F N4 O3 CC(=O)C1=N....
9 3CJO ic50 = 2.2 nM K30 C25 H28 F3 N3 O2 C[N@]1CC[C....
10 2FKY ic50 = 2.6 nM N2T C23 H25 F2 N3 O CN(C1CCNCC....
11 2WOG - ZZD C22 H21 N O2 S c1ccc(cc1)....
12 2PG2 ic50 = 1.7 uM K01 C18 H22 N2 O2 S2 CCN(CC)C(=....
13 2X7D ic50 = 200 nM EGB C16 H18 N2 O2 S CC1(CC2=C(....
14 3HQD - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
15 1II6 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
16 1YRS ic50 = 450 nM L47 C17 H15 Cl N2 O2 CC(=O)N1[C....
17 2X7C ic50 = 2 uM KZ9 C14 H14 N2 O2 S c1cc(cc(c1....
18 2GM1 ic50 = 0.1 uM 2AZ C28 H30 Cl N5 O2 Cc1ccc(cc1....
19 3KEN - ZZD C22 H21 N O2 S c1ccc(cc1)....
20 2UYI ic50 = 0.48 uM K02 C19 H24 N2 O2 S2 CCN(CC)C(=....
21 2X7E - X7E C19 H18 F2 N2 O2 S CC1=C([C@H....
22 4AS7 ic50 = 484 nM 6LX C31 H33 Cl N2 O3 Cc1ccc(cc1....
23 6G6Y ic50 = 0.74 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
24 3K3B ic50 = 0.2 uM L31 C20 H20 N2 O2 Cc1ccc2c(c....
25 2FL2 ic50 = 2 nM N4T C21 H20 F2 N2 O c1ccc(cc1)....
26 3ZCW Kd = 0.47 uM 4A2 C23 H17 F4 N3 O3 COc1ccc(cc....
70% Homology Family (26)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 56 families.
1 2UYM ic50 = 3.1 uM K03 C20 H26 N2 O2 S2 CCN(CC)C(=....
2 3L9H ic50 = 8 nM EMQ C25 H31 F3 N4 O2 CN(C)CCNC(....
3 1Q0B ic50 = 7 uM NAT C14 H16 N2 O3 S CCOC(=O)C1....
4 2FME ic50 = 104 nM 3QC C20 H24 N2 O2 Cc1ccc2c(c....
5 2FL6 ic50 = 38 nM N5T C19 H18 F2 N2 O CN(C)C(=O)....
6 4B7B - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
7 2X2R ic50 = 549 nM X2O C20 H25 N O2 S CC[C@@H](C....
8 2Q2Y ic50 = 1.6 nM MKR C27 H31 F N4 O3 CC(=O)C1=N....
9 3CJO ic50 = 2.2 nM K30 C25 H28 F3 N3 O2 C[N@]1CC[C....
10 2FKY ic50 = 2.6 nM N2T C23 H25 F2 N3 O CN(C1CCNCC....
11 2WOG - ZZD C22 H21 N O2 S c1ccc(cc1)....
12 2PG2 ic50 = 1.7 uM K01 C18 H22 N2 O2 S2 CCN(CC)C(=....
13 2X7D ic50 = 200 nM EGB C16 H18 N2 O2 S CC1(CC2=C(....
14 3HQD - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
15 1II6 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
16 1YRS ic50 = 450 nM L47 C17 H15 Cl N2 O2 CC(=O)N1[C....
17 2X7C ic50 = 2 uM KZ9 C14 H14 N2 O2 S c1cc(cc(c1....
18 2GM1 ic50 = 0.1 uM 2AZ C28 H30 Cl N5 O2 Cc1ccc(cc1....
19 3KEN - ZZD C22 H21 N O2 S c1ccc(cc1)....
20 2UYI ic50 = 0.48 uM K02 C19 H24 N2 O2 S2 CCN(CC)C(=....
21 2X7E - X7E C19 H18 F2 N2 O2 S CC1=C([C@H....
22 4AS7 ic50 = 484 nM 6LX C31 H33 Cl N2 O3 Cc1ccc(cc1....
23 6G6Y ic50 = 0.74 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
24 3K3B ic50 = 0.2 uM L31 C20 H20 N2 O2 Cc1ccc2c(c....
25 2FL2 ic50 = 2 nM N4T C21 H20 F2 N2 O c1ccc(cc1)....
26 3ZCW Kd = 0.47 uM 4A2 C23 H17 F4 N3 O3 COc1ccc(cc....
50% Homology Family (48)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 39 families.
1 2UYM ic50 = 3.1 uM K03 C20 H26 N2 O2 S2 CCN(CC)C(=....
2 3L9H ic50 = 8 nM EMQ C25 H31 F3 N4 O2 CN(C)CCNC(....
3 1Q0B ic50 = 7 uM NAT C14 H16 N2 O3 S CCOC(=O)C1....
4 2FME ic50 = 104 nM 3QC C20 H24 N2 O2 Cc1ccc2c(c....
5 2FL6 ic50 = 38 nM N5T C19 H18 F2 N2 O CN(C)C(=O)....
6 4B7B - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
7 2X2R ic50 = 549 nM X2O C20 H25 N O2 S CC[C@@H](C....
8 2Q2Y ic50 = 1.6 nM MKR C27 H31 F N4 O3 CC(=O)C1=N....
9 3CJO ic50 = 2.2 nM K30 C25 H28 F3 N3 O2 C[N@]1CC[C....
10 2FKY ic50 = 2.6 nM N2T C23 H25 F2 N3 O CN(C1CCNCC....
11 3HQD - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
12 1II6 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
13 1YRS ic50 = 450 nM L47 C17 H15 Cl N2 O2 CC(=O)N1[C....
14 2X7C ic50 = 2 uM KZ9 C14 H14 N2 O2 S c1cc(cc(c1....
15 2GM1 ic50 = 0.1 uM 2AZ C28 H30 Cl N5 O2 Cc1ccc(cc1....
16 3KEN - ZZD C22 H21 N O2 S c1ccc(cc1)....
17 2UYI ic50 = 0.48 uM K02 C19 H24 N2 O2 S2 CCN(CC)C(=....
18 2X7E - X7E C19 H18 F2 N2 O2 S CC1=C([C@H....
19 4AS7 ic50 = 484 nM 6LX C31 H33 Cl N2 O3 Cc1ccc(cc1....
20 6G6Y ic50 = 0.74 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
21 3K3B ic50 = 0.2 uM L31 C20 H20 N2 O2 Cc1ccc2c(c....
22 2FL2 ic50 = 2 nM N4T C21 H20 F2 N2 O c1ccc(cc1)....
23 3ZCW Kd = 0.47 uM 4A2 C23 H17 F4 N3 O3 COc1ccc(cc....
24 1N6M - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
25 2NCD - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
26 1VFW - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
27 2ZFM - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
28 1I5S - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
29 2ZFI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
30 1I6I - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
31 3LRE - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
32 2XT3 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
33 4A14 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
34 2VVG - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
35 3ZFC - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
36 1F9W - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
37 3KAR - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
38 1F9V - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
39 1F9T - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
40 1F9U - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
41 1T5C - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
42 6A20 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
43 3COB - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
44 1SDM - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
45 4FRZ - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
46 5ZBS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
47 5ZBR - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
48 1BG2 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Ligand no: 2; Ligand: MKR; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 MKR 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2Q2Y; Ligand: ADP; Similar sites found with APoc: 733
This union binding pocket(no: 1) in the query (biounit: 2q2y.bio2) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 1GXU 2HP None
2 2NLQ GLY None
3 2VWA PTY None
4 3P9T TCL None
5 4WG0 CHD None
6 2OG2 MLI 0.835655
7 3B9Q MLI 0.993378
8 2Z5F A3P 1.00671
9 2HHP FLC 1.08992
10 5AZC PGT 1.33333
11 2FAH GDP 1.3624
12 5FUS DAO 1.39373
13 2CJW GDP 1.5625
14 5IRR GSP 1.62338
15 5ZXD ATP 1.63488
16 3FKQ ATP 1.63488
17 5VRH OLB 1.63488
18 1Q7E MET 1.63488
19 5IKR ID8 1.63488
20 4B47 GDP 1.65289
21 1WF3 GNP 1.66113
22 2CIX CEJ 1.67224
23 1Z0F GDP 1.67598
24 5U32 GDP 1.69492
25 2XN5 FUN 1.71429
26 2HT6 GDP 1.72414
27 2XN3 ID8 1.74927
28 2IYL GDP 1.76056
29 5B25 4QJ 1.77515
30 4RC8 STE 1.8018
31 5W76 GDP 1.90736
32 1WDT GTP 1.90736
33 2GK6 ADP 1.90736
34 2VDY HCY 1.90736
35 4OI4 ATP 1.90736
36 1TV5 N8E 1.90736
37 3G58 988 1.90736
38 3DEF GDP 1.9084
39 1JJ7 ADP 1.92308
40 1XMV ADP 1.96629
41 3MD0 GDP 1.97183
42 4PPF FLC 2
43 2Q1H AS4 2
44 2ZR9 DTP 2.00573
45 2OBM ADP 2.01729
46 2WPW ACO 2.0649
47 5V3Y 5V8 2.0979
48 1ZPD CIT 2.11268
49 4R43 GDP 2.17984
50 4DCT GDP 2.17984
51 5XDR ADP 2.17984
52 1TQ4 GDP 2.17984
53 3EC1 GDP 2.17984
54 6FAA ADP 2.17984
55 4PJ3 ANP 2.17984
56 3HU3 AGS 2.17984
57 4A4Z ANP 2.17984
58 3GFZ FMN 2.17984
59 1Q19 SSC 2.17984
60 2P9T 3PG 2.17984
61 6HSP COA 2.17984
62 1F5N GNP 2.17984
63 6HSJ COA 2.17984
64 4ZNL BEF ADP 2.18978
65 4KBF AMP 2.19178
66 1HBK MYR 2.24719
67 1OXV ANP 2.26629
68 5XC5 GTP 2.27273
69 5UGW GSH 2.28571
70 1EK0 GNP 2.35294
71 4Y4V DAL 2.35988
72 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 2.38095
73 1LFD GNP 2.39521
74 1GUA GNP 2.39521
75 3X1Z GNP 2.39521
76 2B8W ALF 5GP 2.43902
77 1R0X ATP 2.44755
78 1KK1 GNP 2.45232
79 4LYA ATP 2.45232
80 1R6B ADP 2.45232
81 1G7S GDP 2.45232
82 4HSE ADP 2.45232
83 5IRN ADP 2.45232
84 4OHY ANP 2.45232
85 3NB0 G6P 2.48276
86 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 2.51046
87 1GP2 GDP 2.54958
88 2F5X ASP 2.5641
89 2QEN ADP 2.57143
90 1D2N ANP 2.57353
91 4JLS 3ZE 2.63158
92 5UQW GDP 2.6455
93 5OCG GNP 2.6455
94 1YRB GDP 2.67176
95 5L3V GDP 2.67559
96 3Q9L ATP 2.69231
97 5YLF BGC 2.69461
98 3BFX A3P 2.7027
99 3TBK ANP 2.7248
100 5WC2 ADP 2.7248
101 2D7D ADP 2.7248
102 2JLR ANP 2.7248
103 5KSZ GCP 2.7248
104 2C9O ADP 2.7248
105 3VMF GTP 2.7248
106 6CRK GDP 2.7248
107 6CGN DA 2.7248
108 6CB2 OLC 2.73038
109 4WH9 3M8 2.73224
110 1Y3A GDP 2.73556
111 5X40 ACP 2.73973
112 4U5X GNP 2.80899
113 3E5H GNP 2.80899
114 1X1R GDP 2.80899
115 1BH2 GSP 2.85714
116 5X3R 7Y3 2.92683
117 1G16 GDP 2.94118
118 5L3W GDP 2.94118
119 3QKT ANP 2.94985
120 3RAB GNP 2.95858
121 2EW1 GNP 2.98507
122 1KAO GDP 2.99401
123 3EZ2 ADP 2.99728
124 5WLB GNP 3.01205
125 3KUD GDP 3.01205
126 1WQ1 GDP 3.01205
127 2F9L GDP 3.01508
128 1F6B GDP 3.0303
129 5L3S GNP 3.04054
130 6A56 LAT 3.04878
131 4PX9 ADP 3.08219
132 5MVR ADP 3.08642
133 4QBK 3NZ 3.09278
134 1OIV GDP 3.14136
135 1OIX GDP 3.14136
136 1XX6 ADP 3.14136
137 1VKJ A3P 3.15789
138 6BR8 PGV 3.1746
139 5UC4 83S 3.18182
140 2WJG GDP 3.19149
141 1NJF ADP 3.2
142 1NJF AGS 3.2
143 4E2J MOF 3.2
144 3BER AMP 3.21285
145 2BME GNP 3.22581
146 4LJ9 ACP 3.24484
147 4TTQ ATP 3.25581
148 5LX9 OLB 3.25733
149 5M04 GDP 3.26975
150 2IS6 ADP 3.26975
151 4KVA GTP 3.26975
152 5FTB ANP 3.26975
153 4NCN GTP 3.26975
154 4OKD GLC GLC GLC 3.26975
155 5FHD ADP ALF 3.26975
156 2Z49 AMG 3.26975
157 3B9Z CO2 3.26975
158 5OLK DTP 3.26975
159 6AU6 GDP 3.26975
160 3IIJ ADP 3.33333
161 5JCZ GDP 3.35196
162 3K7S R52 3.35196
163 2WIC GNP 3.37079
164 2PL3 ADP 3.38983
165 4LX0 BEF GDP 3.38983
166 1TAD GDP 3.39506
167 1TAD ALF 3.39506
168 4DE3 DN8 3.42205
169 2A5F GTP 3.42857
170 2BHW NEX 3.44828
171 5XG5 A2G 3.44828
172 1FP6 ADP 3.46021
173 4NON GDP 3.46154
174 6FA4 GNP 3.46821
175 5J1J ANP 3.50877
176 1XQP 8HG 3.51562
177 1Z08 GNP 3.52941
178 4D81 ADP 3.53357
179 4FCW ADP 3.53698
180 3WYA GDP 3.54223
181 5LTJ ADP 3.54223
182 5BN3 ADP 3.54223
183 5LTJ BEF 3.54223
184 4RD0 GDP 3.54223
185 5VHC BEF ADP 3.54223
186 3WXM GTP 3.54223
187 1YVD GNP 3.5503
188 3KC1 2T6 3.56083
189 3CHT 4NB 3.57143
190 2WJH GDP 3.61446
191 2WJH FLC 3.61446
192 3RMK BML 3.61446
193 3GJ4 GDP 3.61991
194 3GJ0 GDP 3.61991
195 3GJ5 GDP 3.61991
196 3GJ8 GDP 3.61991
197 1ONI BEZ 3.62319
198 5L3R GCP 3.65448
199 1NST A3P 3.69231
200 5BQ5 ADP BEF 3.7037
201 1IBR GNP 3.7037
202 6AIC AMP 3.73832
203 4R2I ANP 3.80952
204 3CPJ GDP 3.81471
205 2CE7 ADP 3.81471
206 2XAU ADP 3.81471
207 4IEE AGS 3.81471
208 6B4K ANP 3.81471
209 5VGR GDP 3.81471
210 4YUS FMN 3.81471
211 5K5Z ANP 3.82166
212 2XTN GTP 3.84615
213 1NF8 BOG 3.86473
214 3I6B KDO 3.88889
215 6BR9 PGV 3.89972
216 6BR9 6OU 3.89972
217 5SZH GNP 3.94089
218 6CS8 F9Y 3.9604
219 2JC9 ADN 3.96396
220 1UJ2 C5P 3.96825
221 2HF9 GSP 3.9823
222 2HJ3 FAD 4
223 3T1O GDP 4.0404
224 3T12 GDP ALF 4.0404
225 1AQU A3P 4.0404
226 5ZB0 ADP 4.0404
227 5ZB0 TYD 4.0404
228 4R98 GNH 4.05904
229 4RZ3 ADP 4.0678
230 3TKL GTP 4.08163
231 3U6B GDP 4.08719
232 2HCJ GDP 4.08719
233 3U6K GDP 4.08719
234 1D8T GDP 4.08719
235 4G5G GDP 4.08719
236 5JBQ GDP 4.08719
237 1DAR GDP 4.08719
238 5GOE GDP 4.08719
239 2BVN GNP 4.08719
240 4YJ1 ADP 4.08719
241 2C77 GNP 4.08719
242 2C78 GNP 4.08719
243 2O1V ADP 4.08719
244 1OYY AGS 4.08719
245 2PX6 DH9 4.11392
246 3REF GDP 4.12371
247 4WZ6 ATP 4.13793
248 4IS0 1R4 4.14938
249 1B0U ATP 4.19847
250 3CNL GNP 4.19847
251 5WGQ EST 4.21456
252 5WGD EST 4.21456
253 5DXE EST 4.21456
254 5DX3 EST 4.21456
255 5DXG EST 4.21456
256 2CBZ ATP 4.21941
257 5IFS ADP 4.21941
258 1SQ5 ADP 4.22078
259 3A4M ADP 4.23077
260 1ZD9 GDP 4.25532
261 5HYR EST 4.26357
262 4MGA 27L 4.31373
263 4MGB XDH 4.31373
264 4TUZ 36J 4.31373
265 4MG8 27J 4.31373
266 4MG7 27H 4.31373
267 4MGD 27N 4.31373
268 2FH5 GTP 4.32432
269 3B7G ANP 4.34783
270 4TMZ GSP 4.34783
271 4HDO GNP 4.34783
272 4HDQ GNP 4.34783
273 1OE0 TTP 4.34783
274 2DPY ADP 4.35967
275 3G5N PB2 4.35967
276 5HR5 ADP 4.35967
277 4H1V GNP 4.35967
278 6H5E ANP 4.35967
279 1K6M AGS 4.35967
280 5M36 9SZ 4.36681
281 2BCG GDP 4.36893
282 2BCG GER 4.36893
283 4TV1 36M 4.38247
284 3UUD EST 4.38247
285 5IUY BOG 4.41501
286 3SFV GDP 4.41989
287 6G14 G4P 4.42177
288 2CHG ANP 4.42478
289 5G3Y ADP 4.42478
290 5CK5 GDP 4.43038
291 1E96 GTP 4.4335
292 3VX3 ADP 4.43548
293 5O74 GDP 4.44444
294 2CDN ADP 4.47761
295 1YYE 196 4.47761
296 3DKP ADP 4.4898
297 5XKT GNP 4.5
298 1ION ADP 4.52675
299 3TK1 GDP 4.54545
300 3BOS CDP 4.54545
301 1WA5 GTP 4.54545
302 3NKV GNP 4.57143
303 5H4S RAM 4.57746
304 3IO3 ADP 4.5977
305 5JCP GDP ALF 4.63215
306 5Y6N ADP 4.63215
307 3X01 AMP 4.63215
308 1SVM ATP 4.63215
309 5TB5 GDP 4.66667
310 2BEK ATP 4.66926
311 4NB5 2JT 4.67836
312 5TAR GDP 4.72973
313 4ZI2 GNP 4.73684
314 2OFW ADX 4.80769
315 4YDS ATP 4.82456
316 1VG0 GDP 4.83092
317 1VG8 GNP 4.83092
318 2W83 GTP 4.84848
319 2IL4 COA 4.85437
320 2ZEJ GDP 4.8913
321 5UWS GNP 4.8951
322 5UWP GNP 4.8951
323 5DI9 GNP 4.8951
324 5UWW GNP 4.8951
325 5UWH GNP 4.8951
326 6CIT GNP 4.8951
327 5UWI GNP 4.8951
328 5UWQ GNP 4.8951
329 5UWU GNP 4.8951
330 5UWR GNP 4.8951
331 5DIF GNP 4.8951
332 5UWJ GNP 4.8951
333 5UWT GNP 4.8951
334 5UWO GNP 4.8951
335 5DHF GNP 4.8951
336 4AG5 ADP 4.90463
337 4J0Q GDP 4.90463
338 4ZKD GDP 4.90463
339 1FNN ADP 4.90463
340 1YC4 43P 4.90463
341 4QOS ADP 4.90566
342 3N5C GDP 4.93827
343 3PCR GTP 4.93827
344 2W58 ADP 4.9505
345 4I90 CHT 4.9505
346 2ODE ALF GDP 4.96454
347 4C01 QY9 4.96454
348 1FZQ GDP 4.97238
349 1U3R 338 4.97925
350 1RRC ADP 4.98339
351 3UIE ANP 5
352 4HAT GNP 5
353 2YJD YJD 5
354 4J26 EST 5
355 5H68 AGS 5
356 3OLL EST 5
357 4J24 EST 5
358 6HKE LMR 5.03145
359 6HKE MLT 5.03145
360 3AB4 THR 5.05618
361 1G3Q ADP 5.06329
362 3P4X ADP 5.08475
363 1JR8 FAD 5.12821
364 4RYV ZEA 5.16129
365 3W54 RNB 5.16717
366 1Z0A GDP 5.17241
367 1OFH ADP 5.17241
368 3QBT GNP 5.17241
369 4LHW GNP 5.17241
370 3TNF GNP 5.17241
371 5W7Q GDP 5.17711
372 5MZN ADP 5.17711
373 5Z69 AGS 5.17711
374 1QHG ATP 5.17711
375 3HR1 PF9 5.17711
376 2PZE ATP 5.24017
377 3ZQ6 ADP ALF 5.24691
378 5KSP GDP 5.26316
379 5EE5 GTP 5.26316
380 1KSH GDP 5.26316
381 3EWA ANP 5.2795
382 5KUT GDP 5.29101
383 1G7C 5GP 5.31915
384 5O2T GSP 5.32544
385 4E03 ADP 5.33981
386 4LC1 GDP 5.34125
387 2QZ4 ADP 5.34351
388 1RYH GNP 5.41872
389 1Y63 ADP 5.43478
390 4URX FK1 5.44959
391 2FSH ANP 5.44959
392 6BVK EAV 5.44959
393 6BVM EBV 5.44959
394 6BVL EBY 5.44959
395 6BVI EC4 5.44959
396 6BVJ EAS 5.44959
397 6BVL GNP 5.44959
398 6D5L GNP 5.44959
399 6D59 GNP 5.44959
400 6D5V GNP 5.44959
401 6D5M GNP 5.44959
402 6BVJ GNP 5.44959
403 6D56 GNP 5.44959
404 6BVM GNP 5.44959
405 6D5E GNP 5.44959
406 6D5H GNP 5.44959
407 6D5J GNP 5.44959
408 6D55 GNP 5.44959
409 6D5G GNP 5.44959
410 6BVI GNP 5.44959
411 6BVK GNP 5.44959
412 5IKI A9H 5.44959
413 1NVV GNP 5.44959
414 1OS1 ATP 5.44959
415 1OS1 PYR 5.44959
416 2YLD CMO 5.51181
417 1L2T ATP 5.53191
418 2BJ4 OHT 5.55556
419 2PEZ DAT 5.58659
420 3FYH ADP 5.59006
421 3PQC GDP 5.64103
422 4PC3 GDP 5.67376
423 1M7G AV2 5.6872
424 1IN4 ADP 5.68862
425 1HTW ADP 5.6962
426 1KO8 6PG 5.71429
427 5H7K GDP 5.72207
428 5H7J GCP 5.72207
429 1XVB 3BR 5.72207
430 5IM3 DTP 5.72207
431 4IOK XPO 5.72207
432 4IOK ADP 5.72207
433 2CB8 MYA 5.74713
434 3B5J 12D 5.76132
435 5N1P 8GK 5.82524
436 4GOJ GNP 5.83333
437 4DOO DAO 5.85366
438 1R4A GNP 5.88235
439 1BO4 COA 5.95238
440 1NRJ GTP 5.9633
441 1XKV ATP 5.99455
442 3RC3 ANP 5.99455
443 1XP8 AGS 6.01093
444 1V6A TRE 6.0241
445 2OZE AGS 6.04027
446 4DK7 0KS 6.07287
447 1ZCB GDP 6.07735
448 1CR1 TTP 6.08108
449 1FQK GDP 6.12245
450 3IUY AMP 6.14035
451 1YZG GDP 6.14525
452 5EXT ADP 6.15385
453 3ET3 ET1 6.16438
454 4QRH 0O2 6.19048
455 4K81 GTP 6.20155
456 1S8F GDP 6.21469
457 4BQS ADP 6.25
458 1JI0 ATP 6.25
459 1IHU AF3 6.26703
460 1IHU ADP 6.26703
461 3M1I GTP 6.39269
462 1OQC FAD 6.4
463 1ZJ6 G3D 6.41711
464 1ECM TSA 6.42202
465 5TSH ADP 6.53951
466 5TSH ANP 6.53951
467 5W75 SUC 6.53951
468 5W75 GDP 6.53951
469 1YTM ATP 6.53951
470 4XGU ADP 6.53951
471 5CX6 CDP 6.53951
472 5ICK FEZ 6.55022
473 4U00 ADP 6.55738
474 4CVN ADP 6.56934
475 3A1S GDP 6.58915
476 4LSJ LSJ 6.58915
477 2PRG BRL 6.64207
478 1SVI GDP 6.66667
479 3BQD DAY 6.66667
480 1G0H IPD 6.74603
481 1Z0J GTP 6.77966
482 2A5J GDP 6.80628
483 5LB3 ADP 6.81199
484 3FWY ADP 6.81199
485 2GDJ ANP 6.81818
486 3O01 DXC 6.81818
487 5V03 658 6.86275
488 1VHT BA3 6.88073
489 3KO0 TFP 6.93069
490 1G6O ADP 6.9697
491 5H67 ATP 7.03518
492 4XTR ADP 7.06215
493 4XTR ATP 7.06215
494 4XVU ATP 7.06215
495 2WOJ ADP ALF 7.06215
496 3ZS9 ADP ALF 7.06215
497 1W0J ADP 7.08447
498 2WKQ GTP 7.08447
499 6DIO CIT 7.08447
500 1W0J ADP BEF 7.08447
501 3GJX GTP 7.08447
502 3WYG GTP 7.14286
503 1Z2A GDP 7.14286
504 1FQJ GDP 7.14286
505 2ZX2 RAM 7.17949
506 2EFE GNH 7.18232
507 1NU4 MLA 7.2165
508 3Q72 GNP 7.22892
509 2RCN GDP 7.26257
510 5GVR LMR 7.26496
511 5HCN GCP 7.27969
512 3E70 GDP 7.31707
513 2GKS ADP 7.35695
514 2IXE ATP 7.38007
515 5HCV 60R 7.393
516 1D5C GDP 7.40741
517 1H65 GDP 7.40741
518 4LPS GDP 7.43802
519 1SBR VIB 7.5
520 1I0B PEL 7.53012
521 1YZN GNP 7.56757
522 2D2F ADP 7.6
523 4QM7 GTP 7.60234
524 5TVI MYR 7.6087
525 1NY5 ADP 7.62943
526 3KTA AP5 7.69231
527 6C90 ADP 7.69231
528 5F90 GLA GAL 7.69231
529 2F2G HMH 7.69231
530 1XEX ATP 7.69231
531 5F90 GLA GAL BGC 5VQ 7.69231
532 5F90 LMR 7.69231
533 3T5G GDP 7.73481
534 4G86 BNT 7.74648
535 4V03 ADP 7.7821
536 4O4Z N2O 7.79221
537 3FVQ ATP 7.79944
538 3BD9 A3P 7.85714
539 6BSX GDP 7.86517
540 1G41 ADP 7.88288
541 1I7E IBS 7.92453
542 2ZTS ADP 7.96813
543 5X13 HC4 7.97872
544 3WYF GTP 7.98319
545 5DI3 GNP 7.98479
546 3QF7 ANP 8
547 6B8B ADP 8.03213
548 4BAS GNP 8.0402
549 1LVG ADP 8.08081
550 4D0N GDP 8.10811
551 5KDO GDP 8.10811
552 3AB3 GDP 8.13008
553 2GJ8 ALF GDP 8.13953
554 3GJ7 GDP 8.16327
555 1SKQ GDP 8.17439
556 4YS0 ADP 8.17439
557 2XTZ GSP 8.19209
558 1GOT GDP 8.21918
559 5E95 GDP 8.24742
560 1G8S MET 8.26087
561 1GWN GTP 8.29268
562 3W5J GDP 8.33333
563 4DKX GDP 8.33333
564 1O3Y GTP 8.43373
565 1J2J GTP 8.43373
566 4KFU ACP 8.49057
567 1VG1 GDP 8.64865
568 1VG9 GDP 8.64865
569 2AWN ADP 8.71935
570 5M7P ADP 8.71935
571 1OW3 GDP 8.80829
572 1MR3 G3D 8.83978
573 1CS4 GSP 8.96226
574 3B6C SDN 8.97436
575 5FG3 GDP 8.99183
576 5Z2M GTP 9.09091
577 5I8F ML1 9.09091
578 1M7B GTP 9.23913
579 4M9Q GNP 9.2511
580 1MKY GDP 9.26431
581 1U0J ADP 9.3633
582 1DS6 GDP 9.375
583 5LEF GTP 9.42408
584 3FAL REA 9.50413
585 6A5Y 9CR 9.66387
586 1JJV ATP 9.70874
587 1G6H ADP 9.72763
588 1RE0 GDP 9.7561
589 1S9D GDP 9.7561
590 2UW1 GVM 9.76331
591 1D2E GDP 9.80926
592 1DKF OLA 9.87124
593 4P4T GDP 10
594 2Y8E GNP 10.0559
595 1FHX 4IP 10.0775
596 1YQT ADP 10.0817
597 4ZDJ UTP 10.0817
598 2A9K GDP 10.1604
599 4TL6 ANP 10.2767
600 4YLG GDP 10.4046
601 4YMU ATP 10.4167
602 4V1F BQ1 10.4651
603 2FFQ GSP 10.5263
604 4KAX GTP 10.559
605 1YZQ GNP 10.5882
606 2G77 AF3 10.6061
607 2G77 GDP 10.6061
608 1Z6T ADP 10.6267
609 2J59 GTP 10.7143
610 2QN6 GDP 10.7527
611 3CX8 GSP 10.8374
612 1UAD GNP 10.8571
613 1ZC3 GNP 10.8571
614 3AQ4 GDP 10.8696
615 4DID GDP 10.8808
616 1NF3 GNP 10.9375
617 2GCO GNP 10.9453
618 2GCN GDP 10.9453
619 5XJ7 87O 10.9453
620 2CK3 ANP 10.9589
621 2CK3 ADP 10.9589
622 4P3Y GDP 10.989
623 2NGR GDP 10.9948
624 1A4R GNH 10.9948
625 1A4R GDP 10.9948
626 1GRN AF3 10.9948
627 2NGR AF3 10.9948
628 1GRN GDP 10.9948
629 4ITR GDP 10.9948
630 5BXQ GDP 11.0236
631 2WMO GTP 11.0526
632 3BFV ADP 11.0701
633 5OCA 9QZ 11.1111
634 1Z06 GNP 11.1111
635 3RLF ANP 11.1717
636 4C4P GNP 11.215
637 1U8Z GDP 11.3095
638 1RJ9 GCP 11.3333
639 3ET1 ET1 11.3402
640 1KMQ GNP 11.413
641 2GBB CIT 11.5385
642 4YC7 GNP 11.6022
643 2X77 GDP 11.6402
644 3DDC GNP 11.6564
645 4XOI GTP 11.6667
646 5CHR 4NC 11.6788
647 1TU3 GNP 11.6959
648 1R2Q GNP 11.7647
649 5IRC GDP 11.828
650 3LXR GDP 11.8919
651 6BC0 GSP 11.8919
652 6BCA GSP 11.8919
653 6BCB GSP 11.8919
654 3RWO GDP 11.8919
655 3MJH GTP 11.9048
656 1I4D GDP 11.9792
657 1KY3 GDP 12.0879
658 2W2X GSP 12.0968
659 3VPD BUA 12.0996
660 3GJ3 GDP 12.1212
661 3DZD ADP 12.2616
662 4XSH GSP 12.2905
663 3SBD GNP 12.2995
664 3ZIA ADP 12.3188
665 3ZIA ATP 12.3188
666 5UIV ADP 12.3348
667 1MH1 GNP 12.3656
668 1TX4 ALF GDP 12.4294
669 1G4U AF3 12.5
670 1G4U GDP 12.5
671 2DT9 THR 12.5749
672 3AQT RCO 12.6531
673 3BC1 GNP 12.8205
674 2FJU GSP 12.9213
675 2WOR 2AN 13
676 1Z0K GTP 13.0435
677 1HE1 AF3 13.0682
678 1HE1 GDP 13.0682
679 4IHQ ADP 13.079
680 5OEC GDP 13.1148
681 2FNA ADP 13.1653
682 3Q85 GNP 13.6095
683 2V7Q ATP 13.6364
684 2V7Q ADP 13.6364
685 2J0V GDP 13.6792
686 1M2O GNP 13.6842
687 4KVG GTP 13.8462
688 2ZPA ADP 14.1689
689 1PUJ GNP 14.1844
690 1M2Z BOG 14.2857
691 3GN8 DEX