Receptor
PDB id Resolution Class Description Source Keywords
2nnj 2.28 Å EC: 1.14.14.1 CYP2C8DH COMPLEXED WITH FELODIPINE HOMO SAPIENS CYP2C8; HUMAN P450 2C8; MONOOXYGENASES; FELODIPINE; PLENDIL;INHIBITOR COMPLEX; PALMITIC ACID OXIDOREDUCTASE ELECTRON T
Ref.: DETERMINANTS OF CYTOCHROME P450 2C8 SUBSTRATE BINDI STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZ FELODIPINE, AND 9-CIS-RETINOIC ACID. J.BIOL.CHEM. V. 283 17227 2008
Ligand Information
Ligand Validity Binding Data Ligand Warnings Chemaxon Viewer Molecular Weight (Da) Formula SMILES
SO4 Invalid - none 96.063
O4 S
[O-]S(=O)(=O)[O-]
225 Valid Ki = 90 nM none 384.254
C18 H19 Cl2 N O4
CCOC(=O)C1=C(NC(=C([C@H]1c2cccc(c2Cl)Cl)C(=O)OC)C)C
PLM Invalid - none 256.424
C16 H32 O2
CCCCCCCCCCCCCCCC(=O)O
HEM Part of Protein - none 616.487
C34 H32 Fe N4 O4
Cc1c2/cc/3 c(/cc4/c(c(/c(/[nH]4)c/c5n/c(cc(c1CCC(=O)O)[nH]2)/C(=C5C)CCC(=O)O)C=C)C)C(=C3C)C=C
90% Homology Family

The Class containing this family consists of a total of 10 families.

Leader:    2NNJ     CYP2C8DH COMPLEXED WITH FELODIPINE
No: PDB id Binding Data Representative ligand
1 2NNJ Ki = 90 nM 225
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