-->
Receptor
PDB id Resolution Class Description Source Keywords
2g72 2 Å EC: 2.1.1.28 STRUCTURE OF HPNMT WITH INHIBITOR 3-FLUOROMETHYL-7- THIOMORPHOLINOSULFONAMIDE-THIQ AND ADOMET HOMO SAPIENS METHYLTRANSFERASE TRANSFERASE
Ref.: ENZYME ADAPTATION TO INHIBITOR BINDING: A CRYPTIC B SITE IN PHENYLETHANOLAMINE N-METHYLTRANSFERASE J.MED.CHEM. V. 50 4845 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
F21 A:4001;
B:4002;
Valid;
Valid;
none;
none;
Ki = 315 nM
330.441 C14 H19 F N2 O2 S2 c1cc2...
SAM A:2001;
B:2002;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2OBF 2.3 Å EC: 2.1.1.28 STRUCTURE OF K57A HPNMT WITH INHIBITOR 3-HYDROXYMETHYL-7-(N- CHLOROPHENYLAMINOSULFONYL)-THIQ AND ADOHCY (SAH) HOMO SAPIENS METHYLTRANSFERASE TRANSFERASE
Ref.: ENZYME ADAPTATION TO INHIBITOR BINDING: A CRYPTIC B SITE IN PHENYLETHANOLAMINE N-METHYLTRANSFERASE J.MED.CHEM. V. 50 4845 2007
Members (30)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3KPV Kd = 180 uM ADE C5 H5 N5 c1[nH]c2c(....
2 3KQV - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3KR2 Kd = 7.2 uM ET2 C7 H6 F N3 c1cc2c(cc1....
4 3KQY Kd = 15 uM ES0 C7 H7 N3 O c1cc2c(c(c....
5 3KQP Kd = 380 uM ES5 C9 H8 N2 c1cc2cc(cc....
6 2G70 Ki = 17 nM HNT C10 H12 N2 O3 c1cc2c(cc1....
7 3KQS Kd = 6.3 uM AX7 C7 H7 N3 c1ccc2c(c1....
8 3KQO Kd = 140 uM ES4 C5 H3 Cl N4 c1[nH]c2c(....
9 3HCD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 2G8N Ki = 0.063 uM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
11 3HCB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 3HCC Ki = 13 uM LT3 C12 H12 F3 N c1cc2c(c(c....
13 3KQW Kd = 97 uM ES9 C7 H5 Cl N2 c1cc2c(cc1....
14 2G72 Ki = 315 nM F21 C14 H19 F N2 O2 S2 c1cc2c(cc1....
15 3KQQ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 3HCA - OTR C8 H11 N O2 c1cc(ccc1[....
17 3KPU Kd = 690 uM ES1 C9 H7 N O c1ccc2c(c1....
18 1YZ3 Ki = 1.55 nM SKA C9 H9 Cl2 N c1cc(c(c2c....
19 2AN4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
20 2G71 Ki = 35 nM FTS C13 H16 F4 N2 O2 S c1cc2c(cc1....
21 1HNN Ki = 0.58 uM SKF C9 H12 N2 O2 S c1cc2c(cc1....
22 3KPW Kd = 14 uM 1SQ C9 H8 N2 c1ccc2c(c1....
23 3KR1 Kd = 1.8 uM VGD C7 H6 Cl N3 c1cc2c(cc1....
24 2AN3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
25 3KPJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
26 3KQT Kd = 4.6 uM ES7 C8 H9 N3 Cn1c2ccccc....
27 2OBF Ki = 1.4 nM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
28 2AN5 Ki = 2.1 uM TTL C10 H13 N O c1ccc2c(c1....
29 3KQM Kd = 170 uM ES3 C3 H3 Br N2 c1c(nc[nH]....
30 3KPY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (30)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3KPV Kd = 180 uM ADE C5 H5 N5 c1[nH]c2c(....
2 3KQV - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3KR2 Kd = 7.2 uM ET2 C7 H6 F N3 c1cc2c(cc1....
4 3KQY Kd = 15 uM ES0 C7 H7 N3 O c1cc2c(c(c....
5 3KQP Kd = 380 uM ES5 C9 H8 N2 c1cc2cc(cc....
6 2G70 Ki = 17 nM HNT C10 H12 N2 O3 c1cc2c(cc1....
7 3KQS Kd = 6.3 uM AX7 C7 H7 N3 c1ccc2c(c1....
8 3KQO Kd = 140 uM ES4 C5 H3 Cl N4 c1[nH]c2c(....
9 3HCD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 2G8N Ki = 0.063 uM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
11 3HCB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 3HCC Ki = 13 uM LT3 C12 H12 F3 N c1cc2c(c(c....
13 3KQW Kd = 97 uM ES9 C7 H5 Cl N2 c1cc2c(cc1....
14 2G72 Ki = 315 nM F21 C14 H19 F N2 O2 S2 c1cc2c(cc1....
15 3KQQ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 3HCA - OTR C8 H11 N O2 c1cc(ccc1[....
17 3KPU Kd = 690 uM ES1 C9 H7 N O c1ccc2c(c1....
18 1YZ3 Ki = 1.55 nM SKA C9 H9 Cl2 N c1cc(c(c2c....
19 2AN4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
20 2G71 Ki = 35 nM FTS C13 H16 F4 N2 O2 S c1cc2c(cc1....
21 1HNN Ki = 0.58 uM SKF C9 H12 N2 O2 S c1cc2c(cc1....
22 3KPW Kd = 14 uM 1SQ C9 H8 N2 c1ccc2c(c1....
23 3KR1 Kd = 1.8 uM VGD C7 H6 Cl N3 c1cc2c(cc1....
24 2AN3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
25 3KPJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
26 3KQT Kd = 4.6 uM ES7 C8 H9 N3 Cn1c2ccccc....
27 2OBF Ki = 1.4 nM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
28 2AN5 Ki = 2.1 uM TTL C10 H13 N O c1ccc2c(c1....
29 3KQM Kd = 170 uM ES3 C3 H3 Br N2 c1c(nc[nH]....
30 3KPY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3KPV Kd = 180 uM ADE C5 H5 N5 c1[nH]c2c(....
2 3KQV - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3KR2 Kd = 7.2 uM ET2 C7 H6 F N3 c1cc2c(cc1....
4 3KQY Kd = 15 uM ES0 C7 H7 N3 O c1cc2c(c(c....
5 3KQP Kd = 380 uM ES5 C9 H8 N2 c1cc2cc(cc....
6 2G70 Ki = 17 nM HNT C10 H12 N2 O3 c1cc2c(cc1....
7 3KQS Kd = 6.3 uM AX7 C7 H7 N3 c1ccc2c(c1....
8 3KQO Kd = 140 uM ES4 C5 H3 Cl N4 c1[nH]c2c(....
9 3HCD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 2G8N Ki = 0.063 uM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
11 3HCB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 3HCC Ki = 13 uM LT3 C12 H12 F3 N c1cc2c(c(c....
13 3KQW Kd = 97 uM ES9 C7 H5 Cl N2 c1cc2c(cc1....
14 2G72 Ki = 315 nM F21 C14 H19 F N2 O2 S2 c1cc2c(cc1....
15 3KQQ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 3HCA - OTR C8 H11 N O2 c1cc(ccc1[....
17 3KPU Kd = 690 uM ES1 C9 H7 N O c1ccc2c(c1....
18 1YZ3 Ki = 1.55 nM SKA C9 H9 Cl2 N c1cc(c(c2c....
19 2AN4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
20 2G71 Ki = 35 nM FTS C13 H16 F4 N2 O2 S c1cc2c(cc1....
21 1HNN Ki = 0.58 uM SKF C9 H12 N2 O2 S c1cc2c(cc1....
22 3KPW Kd = 14 uM 1SQ C9 H8 N2 c1ccc2c(c1....
23 3KR1 Kd = 1.8 uM VGD C7 H6 Cl N3 c1cc2c(cc1....
24 2AN3 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
25 3KPJ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
26 3KQT Kd = 4.6 uM ES7 C8 H9 N3 Cn1c2ccccc....
27 2OBF Ki = 1.4 nM F83 C16 H17 Cl N2 O3 S c1cc(ccc1N....
28 2AN5 Ki = 2.1 uM TTL C10 H13 N O c1ccc2c(c1....
29 3KQM Kd = 170 uM ES3 C3 H3 Br N2 c1c(nc[nH]....
30 3KPY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
31 5YJI ic50 = 5 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
32 5XVK ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
33 5YJF ic50 = 1.8 uM 8WO C8 H12 N2 O2 CN1CC(=CC=....
34 5XVQ ic50 = 9 uM 8GC C7 H9 N2 O C[n+]1cccc....
35 6CHH - F0P C24 H32 N8 O6 c1cc(cc(c1....
36 2A14 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: F21; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 F21 1 1
2 FTS 0.473684 0.825397
Ligand no: 2; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2OBF; Ligand: F83; Similar sites found with APoc: 418
This union binding pocket(no: 1) in the query (biounit: 2obf.bio3) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 1RV1 IMZ None
2 1BC5 SAH 1.03806
3 2BOY BHO 1.1811
4 3SJ7 NDP 1.5873
5 5LOG SAH 1.71674
6 4PBG BGP 1.7301
7 2YY7 NAD 1.7301
8 3DUW SAH 1.79372
9 4FGC PQ0 1.81818
10 3OU2 SAH 1.83486
11 5GT9 NAP 1.90114
12 1G60 SAM 1.92308
13 4BPZ GLC BGC BGC 1.95312
14 4NBU NAI 2
15 3O7W SAM 2.07612
16 5F8F SFG 2.07612
17 1YXM ADE 2.07612
18 1G55 SAH 2.07612
19 6FDF SAH 2.07612
20 3LKZ SFG 2.07612
21 2P41 SAH 2.07612
22 3VC1 GST 2.07612
23 3VC1 SAH 2.07612
24 4TO8 FLC 2.07612
25 6EOF ADP 2.07612
26 3FPF TNA 2.07612
27 1U2Z SAH 2.07612
28 3C6K MTA 2.07612
29 3C6K SPD 2.07612
30 3FPF MTA 2.07612
31 4YMH SAH 2.08333
32 1ZQ9 SAM 2.10526
33 1NV8 MEQ 2.11268
34 1NV8 SAM 2.11268
35 4PO2 ASN ARG LEU LEU LEU THR GLY 2.12766
36 3EVG SAH 2.18182
37 5ME4 HP4 2.18978
38 1H5Q NAP 2.26415
39 4NEC SAH 2.27273
40 2PWY SAH 2.32558
41 1ZTH ADP 2.32558
42 1SWG BTN 2.34375
43 1GEG NAD 2.34375
44 3FGZ BEF 2.34375
45 3H8V ATP 2.39726
46 4URF NAD 2.41935
47 4KIB SAH 2.42215
48 4Y9D NAI 2.42215
49 1FP2 SAH 2.42215
50 5DNK SAH 2.42215
51 1SQF SAM 2.42215
52 3TKY SAH 2.42215
53 3A06 NDP 2.42215
54 3M6W SAM 2.42215
55 1DL5 SAH 2.42215
56 1W8D NAP 2.42215
57 1W6U NAP 2.42215
58 4M73 M72 2.42215
59 3VYW SAM 2.42215
60 1W73 NAP 2.42215
61 6GSG RCO 2.42215
62 3JQQ A2P 2.42215
63 4M73 SAH 2.42215
64 4TQ3 GPP 2.42215
65 3NJ4 NAD 2.42215
66 5HR5 ADP 2.42215
67 3T2W BTN 2.45902
68 1LNX URI 2.46914
69 3FUU ADN 2.58303
70 1ZEM NAD 2.67176
71 3VZS NAP 2.72374
72 5W7R SAH 2.76817
73 2FK8 SAM 2.76817
74 1JQD HSM 2.76817
75 1JQD SAH 2.76817
76 2Q1A 2KT 2.76817
77 6C8R SAH 2.76817
78 4DCM SAM 2.76817
79 5W7R 9Z7 2.76817
80 3TLJ SAH 2.76817
81 2BD0 NAP 2.76817
82 5DX1 SFG 2.76817
83 3MCT SAH 2.76817
84 5DX0 SFG 2.76817
85 5DXA SFG 2.76817
86 5DX8 SFG 2.76817
87 5DWQ SFG 2.76817
88 1KGZ PRP 2.76817
89 6C8R EQV 2.76817
90 3MAG SAH 2.76817
91 6HKE LMR 2.76817
92 5VEO AMP 2.76817
93 1V8B NAD 2.76817
94 2GN3 MAN 2.77778
95 1TPY SAH 2.78746
96 1KPH SAH 2.78746
97 1L1E SAH 2.78746
98 1KPG SAH 2.78746
99 5T2U NAP 2.82258
100 1QAN SAH 2.86885
101 4IF4 BEF 2.88462
102 3EGI ADP 2.91262
103 1TL2 NDG 2.9661
104 3LCC SAH 2.97872
105 4IBF 1D5 3.10078
106 6ECW SAH 3.11419
107 6ECU SAH 3.11419
108 3LST SAH 3.11419
109 5KOK SAH 3.11419
110 5XNC MTA 3.11419
111 6C5B SAH 3.11419
112 1FP1 SAH 3.11419
113 3ABI NAD 3.11419
114 5KOK S9T 3.11419
115 4PIO SAH 3.11419
116 4PIO AVI 3.11419
117 2PT9 2MH 3.11419
118 5KOK R9T 3.11419
119 3OJO NAD 3.11419
120 3FRH SAH 3.16206
121 5CK5 GDP 3.16456
122 2I7C AAT 3.18021
123 3GCZ SAM 3.19149
124 3LCV SAM 3.20285
125 3MQ2 SAH 3.21101
126 3DXY SAM 3.21101
127 3G89 SAM 3.21285
128 3QP4 HL0 3.2967
129 4NBT NAD 3.33333
130 3BXO SAM 3.34728
131 4DE3 DN8 3.42205
132 1XTP SAI 3.46021
133 3G2O SAM 3.46021
134 5FUB SAH 3.46021
135 4LHD GLY 3.46021
136 3NIP 16D 3.46021
137 3A25 SAM 3.46021
138 5WAN URA 3.46021
139 3S1S SAH 3.46021
140 3O03 NAP 3.46021
141 5YIF 8VR 3.46021
142 6C4M NAP 3.46021
143 1V08 NTZ 3.46021
144 3JQ8 NAP 3.47222
145 3JQ7 NAP 3.47222
146 2QZO KN1 3.48837
147 1VE3 SAM 3.52423
148 1I1N SAH 3.53982
149 2RIF AMP 3.5461
150 1LSS NAD 3.57143
151 3D3W NAP 3.68852
152 3EW2 BTN 3.7037
153 1UAY ADN 3.71901
154 5ULP KB1 3.73134
155 4TQK NAG 3.80623
156 6C4T NA7 3.80623
157 1SZ2 BGC 3.80623
158 1ZGA SAH 3.80623
159 1JQ3 AAT 3.80623
160 5MGZ SAH 3.81356
161 4KXQ APR 3.91459
162 5BSZ SAH 4
163 5K7U SAM 4
164 5THQ NDP 4.04412
165 3GRU AMP 4.0678
166 5UNJ RJW 4.08163
167 2HYQ MAN MAN 4.09836
168 3GDH SAH 4.14938
169 5WP4 SAH 4.15225
170 3X0D SAH 4.15225
171 6B92 SAH 4.15225
172 3DMH SAM 4.15225
173 3DMH GMP 4.15225
174 2BMB PMM 4.15225
175 5OVL NAP 4.15225
176 2X24 X24 4.15225
177 2ZSC BTN 4.25532
178 5K21 6QF 4.25532
179 1FK8 NAD 4.28016
180 4NBW NAD 4.28016
181 5V6F MAN BMA MAN 4.34783
182 5ICK FEZ 4.36681
183 5N5D SAM 4.42478
184 2VDV SAM 4.47154
185 5BW4 SAM 4.49438
186 2UYQ SAM 4.49827
187 4C4A SAH 4.49827
188 6B3A SAM 4.49827
189 5FA5 MTA 4.49827
190 4UCI SAM 4.49827
191 4GQB 0XU 4.49827
192 2YX1 SFG 4.49827
193 4DMG SAM 4.49827
194 1UOU CMU 4.49827
195 1XHL NDP 4.49827
196 1XKQ NDP 4.49827
197 5FWA J7C 4.49827
198 3FZG SAM 4.5
199 3PCJ INO 4.5
200 6DUB SAH 4.5045
201 3RKR NAP 4.58015
202 5CIC 51R 4.62963
203 3SJU NDP 4.6595
204 5OVK NDP 4.6875
205 3KIF GDL 4.71698
206 6GFK SAH 4.78088
207 3Q87 SAM 4.8
208 4D3F NAP 4.83871
209 5ERG SAM 4.84429
210 3GWZ SAH 4.84429
211 3GXO SAH 4.84429
212 2JJQ SAH 4.84429
213 5LX9 OLB 4.84429
214 2Q28 ADP 4.84429
215 3L9W AMP 4.84429
216 4Y30 SAH 4.84429
217 3FSY SCA 4.84429
218 3L9W GSH 4.84429
219 5JE0 SAH 4.8583
220 5JE0 AZ8 4.8583
221 2AK3 AMP 4.86726
222 2AG5 NAD 4.87805
223 3P2E SAH 4.88889
224 4CQM NAP 4.91803
225 4NV1 TYD 4.93827
226 3PFG SAM 4.94297
227 3PFG TLO 4.94297
228 1I9G SAM 5
229 5U83 ZN8 5.18868
230 4KRG SAH 5.19031
231 6GKV SAH 5.19031
232 4LWP SAH 5.19031
233 4N49 SAM 5.19031
234 3TDC 0EU 5.19031
235 5E72 SAM 5.19031
236 3FW9 SLX 5.19031
237 4Z28 BTN 5.22388
238 2BGM NAJ 5.39568
239 3C3Y SAH 5.48523
240 4FN4 NAD 5.51181
241 5X62 SAH 5.53633
242 1RJD SAM 5.53633
243 5F2K OCA 5.53633
244 5F2K SAH 5.53633
245 5WXU FLC 5.53633
246 6BQ6 TER 5.53633
247 4BLW SAH 5.53633
248 3QWI NAP 5.55556
249 5M58 SAH 5.65217
250 2JAP NDP 5.66802
251 2JAH NDP 5.66802
252 5XLX SAH 5.67376
253 1GEE NAD 5.74713
254 5ZW3 SAH 5.77778
255 2GJ3 FAD 5.83333
256 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 5.85774
257 5W7K SAH 5.88235
258 5E9W SAH 5.88235
259 2AOT SAH 5.88235
260 3WMX NAD 5.88235
261 4XUC SAM 5.9633
262 4XUC 43G 5.9633
263 4TV1 36M 5.9761
264 6HDT BTN 6.01504
265 4JNJ BTN 6.08696
266 1Q0S SAH 6.17761
267 5W7M SAH 6.22837
268 6ECT SAM 6.22837
269 5CKS GAL 6.22837
270 5JJR SAH 6.22837
271 4JIE BMA 6.22837
272 5MPT SAH 6.22837
273 5A6B OAN 6.22837
274 3MB5 SAM 6.27451
275 1EYQ NAR 6.30631
276 3T7S SAM 6.34328
277 5DM1 SAH 6.36704
278 5DM1 5D7 6.36704
279 5DLY SAH 6.39098
280 5DLY 5D7 6.39098
281 4C2W ANP 6.45161
282 4YAC NAI 6.57439
283 3I53 SAH 6.57439
284 2IZ1 ATR 6.57439
285 4M37 SAH 6.57439
286 4M38 SAH 6.57439
287 1F3L SAH 6.57439
288 2OEM 1AE 6.57439
289 1KYZ SAH 6.57439
290 1VBJ CIT 6.57439
291 6D6Y SAH 6.57439
292 5FTW SAH 6.64062
293 5UFN SAH 6.72269
294 5E8J SAH 6.81818
295 2EFJ SAH 6.92042
296 3BGD SAH 6.92042
297 3A27 SAM 6.92042
298 4O1M NAD 6.92042
299 3BGD PM6 6.92042
300 1EJ0 SAM 7.22222
301 1E5Q NDP 7.26644
302 4WGF HX2 7.31707
303 1VAY AZA 7.31707
304 2XYQ SAH 7.37705
305 1R18 SAH 7.48899
306 4POO SAM 7.5
307 5YEC ATP 7.56302
308 5GM1 SAH 7.61246
309 3VSE SAH 7.61246
310 4A6D SAM 7.61246
311 5EEH P9P 7.61246
312 5EEH SAH 7.61246
313 3CW9 AMP 7.61246
314 2PK3 A2R 7.61246
315 3TN7 NJP 7.61246
316 5JGL SAM 7.61246
317 1O5I NAD 7.63052
318 6CI9 NAP 7.72201
319 1YYE 196 7.83582
320 2NXE SAM 7.87402
321 3R1V AZB 7.87402
322 3H2B SAH 7.88177
323 4FZV SAM 7.94979
324 2O07 MTA 7.95848
325 2O07 SPD 7.95848
326 4E70 N7I 7.95848
327 3A4T SFG 8.0292
328 2DPM SAM 8.09859
329 1Q7B NAP 8.19672
330 1WY7 SAH 8.21256
331 5THZ SAH 8.3045
332 1XDS SAM 8.3045
333 1QZZ SAM 8.3045
334 5THY SAH 8.3045
335 1NW5 SAM 8.3045
336 4Q9N NAI 8.3045
337 5W7B MYR 8.51064
338 4OBW SAM 8.56031
339 5CUQ NSC 8.61423
340 2BZG SAH 8.62069
341 5WP5 SAH 8.65052
342 2ZIF SAM 8.65052
343 1V59 NAD 8.65052
344 2ABJ CBC 8.65052
345 2WA2 SAM 8.69565
346 1U3R 338 8.71369
347 5C9J DAO 8.8968
348 4R6W PC 8.91473
349 4R6W SAH 8.91473
350 5D4V SAH 8.95522
351 3PT9 SAH 8.99654
352 2JHP SAH 8.99654
353 2JHP GUN 8.99654
354 4YSX E23 9.04255
355 4HBM 0Y7 9.16667
356 4KYK IMN 9.23913
357 2PX8 SAH 9.29368
358 3NUG NAD 9.34256
359 1P77 ATR 9.55882
360 4IWN GEK 9.60699
361 2ZWA SAH 9.68858
362 2IF8 ADP 9.68858
363 1X87 NAD 9.68858
364 5TVI O8N 9.78261
365 5GWX SAR 9.85915
366 5GWX SAM 9.85915
367 5L95 AMP 10
368 4AZW SAM 10.0346
369 1JG3 ADN 10.2128
370 1AE1 NAP 10.2564
371 6C4N NAP 10.7266
372 3GU3 SAH 11.0727
373 3H5N ATP 11.0727
374 5ODT ADP 11.3074
375 4ONQ SFG 11.4187
376 2CE7 ADP 11.4187
377 4P86 5GP 11.4754
378 2XVM SAH 11.5578
379 2PXX SAH 11.6279
380 3TKA SAM 11.7647
381 5IL1 SAM 11.7647
382 4N14 WR7 11.7647
383 4QTU SAM 11.8519
384 1WG8 SAM 11.9298
385 1N2X SAM 12.1107
386 1IM8 SAI 12.2951
387 4O0L NDP 12.3636
388 3JWH SAH 12.4424
389 3QOX SAH 13.1488
390 5MW4 5JU 13.1488
391 1Z3C SA8 13.4948
392 1NFQ NAI 13.4948
393 5HJM MTA 13.8408
394 5ICE SAH 13.8408
395 5ICE 2H4 13.8408
396 4KRI SAH 14.1869
397 6F5Z SAH 14.5329
398 3OFK SAH 14.8148
399 1UZN NAP 14.9798
400 2EG5 SAH 15.2249
401 2EJU SAH 15.2249
402 2HMT NAI 15.2778
403 5FA8 SAM 16.7702
404 1ZEI CRS 16.9811
405 1NE6 SP1 17.3145
406 1L3I SAH 18.75
407 1QJI PKF 20.5
408 4PNE SAH 21.7993
409 2ZFU SAH 21.8605
410 1XCL SAH 22.1277
411 5YF1 SFG 22.1453
412 5YF1 8V0 22.1453
413 5E1M SAH 23.6515
414 5E1M PRO PRO LYS ARG ILE ALA 23.6515
415 1P1C SAH 26.1307
416 5JO1 6LM 26.4865
417 3ZC7 ATP 26.9841
418 4OGQ 7PH 29.0323
Pocket No.: 2; Query (leader) PDB : 2OBF; Ligand: SAH; Similar sites found with APoc: 406
This union binding pocket(no: 2) in the query (biounit: 2obf.bio3) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 1BC5 SAH 1.03806
2 3SJ7 NDP 1.5873
3 5G3R 89A 1.7301
4 4BHL ARG 1.7301
5 2YY7 NAD 1.7301
6 3DUW SAH 1.79372
7 3OU2 SAH 1.83486
8 5GT9 NAP 1.90114
9 1G60 SAM 1.92308
10 4NBU NAI 2
11 3O7W SAM 2.07612
12 5F8F SFG 2.07612
13 1YXM ADE 2.07612
14 1G55 SAH 2.07612
15 6FDF SAH 2.07612
16 3LKZ SFG 2.07612
17 2P41 SAH 2.07612
18 3VC1 GST 2.07612
19 3VC1 SAH 2.07612
20 3FPF TNA 2.07612
21 3IX1 NFM 2.07612
22 3C6K SPD 2.07612
23 3C6K MTA 2.07612
24 3FPF MTA 2.07612
25 1U2Z SAH 2.07612
26 2JC9 ADN 2.07612
27 2JK0 ASP 2.07612
28 4YMH SAH 2.08333
29 1ZQ9 SAM 2.10526
30 1NV8 MEQ 2.11268
31 1NV8 SAM 2.11268
32 3EVG SAH 2.18182
33 1H5Q NAP 2.26415
34 4NEC SAH 2.27273
35 3AI3 SOE 2.28137
36 2PWY SAH 2.32558
37 3FGZ BEF 2.34375
38 1GEG NAD 2.34375
39 3H8V ATP 2.39726
40 4URF NAD 2.41935
41 4KIB SAH 2.42215
42 4Y9D NAI 2.42215
43 1FP2 SAH 2.42215
44 5DNK SAH 2.42215
45 3TKY SAH 2.42215
46 1SQF SAM 2.42215
47 3A06 NDP 2.42215
48 5J32 IPM 2.42215
49 3M6W SAM 2.42215
50 1DL5 SAH 2.42215
51 4M73 M72 2.42215
52 4M73 SAH 2.42215
53 1W6U NAP 2.42215
54 1W8D NAP 2.42215
55 3VYW SAM 2.42215
56 1W73 NAP 2.42215
57 3NJ4 NAD 2.42215
58 5HR5 ADP 2.42215
59 5L53 NAP 2.42215
60 3LTW HLZ 2.5
61 3FUU ADN 2.58303
62 4GGZ BTN 2.6087
63 1ZEM NAD 2.67176
64 3VZS NAP 2.72374
65 4B5W PYR 2.73438
66 2Q46 NAP 2.7668
67 5W7R SAH 2.76817
68 2FK8 SAM 2.76817
69 1JQD HSM 2.76817
70 6C8R SAH 2.76817
71 4DCM SAM 2.76817
72 3TLJ SAH 2.76817
73 5DX1 SFG 2.76817
74 2BD0 NAP 2.76817
75 3MCT SAH 2.76817
76 5DXA SFG 2.76817
77 6C8R EQV 2.76817
78 5DX0 SFG 2.76817
79 5DX8 SFG 2.76817
80 3MAG SAH 2.76817
81 1KGZ PRP 2.76817
82 5DWQ SFG 2.76817
83 1JQD SAH 2.76817
84 5VEO AMP 2.76817
85 5W7R 9Z7 2.76817
86 1UKG MMA 2.77778
87 1TPY SAH 2.78746
88 1L1E SAH 2.78746
89 1KPH SAH 2.78746
90 1KPG SAH 2.78746
91 5T2U NAP 2.82258
92 2BVD ISX 2.82686
93 1XG5 NAP 2.86738
94 1QAN SAH 2.86885
95 4IF4 BEF 2.88462
96 3EGI ADP 2.91262
97 3LCC SAH 2.97872
98 4IBF 1D5 3.10078
99 6ECW SAH 3.11419
100 6ECU SAH 3.11419
101 3LST SAH 3.11419
102 5KOK SAH 3.11419
103 5XNC MTA 3.11419
104 6C5B SAH 3.11419
105 3ABI NAD 3.11419
106 1FP1 SAH 3.11419
107 2ZBL BMA 3.11419
108 4PIO SAH 3.11419
109 4PIO AVI 3.11419
110 2PT9 2MH 3.11419
111 5KOK R9T 3.11419
112 5KOK S9T 3.11419
113 3FRH SAH 3.16206
114 2I7C AAT 3.18021
115 3GCZ SAM 3.19149
116 3LCV SAM 3.20285
117 3MQ2 SAH 3.21101
118 3DXY SAM 3.21101
119 3G89 SAM 3.21285
120 4NBT NAD 3.33333
121 3BXO SAM 3.34728
122 4DE3 DN8 3.42205
123 3G2O SAM 3.46021
124 1XTP SAI 3.46021
125 5FUB SAH 3.46021
126 3A25 SAM 3.46021
127 4LHD GLY 3.46021
128 3S1S SAH 3.46021
129 3O03 NAP 3.46021
130 3NIP 16D 3.46021
131 5WAN URA 3.46021
132 5YIF 8VR 3.46021
133 3JQ8 NAP 3.47222
134 2QZO KN1 3.48837
135 1VE3 SAM 3.52423
136 1I1N SAH 3.53982
137 2RIF AMP 3.5461
138 1LSS NAD 3.57143
139 3D3W NAP 3.68852
140 1PR9 NAP 3.68852
141 3EW2 BTN 3.7037
142 1UAY ADN 3.71901
143 5ULP KB1 3.73134
144 5IFS ADP 3.79747
145 4TQK NAG 3.80623
146 6C4T NA7 3.80623
147 4JZ8 CIT 3.80623
148 1SZ2 BGC 3.80623
149 1ZGA SAH 3.80623
150 1JQ3 AAT 3.80623
151 5MGZ SAH 3.81356
152 4V3I ASP LEU THR ARG PRO 3.89105
153 4KXQ APR 3.91459
154 5BSZ SAH 4
155 2HK9 ATR 4
156 5K7U SAM 4
157 5THQ NDP 4.04412
158 3GRU AMP 4.0678
159 3GDH SAH 4.14938
160 3X0D SAH 4.15225
161 6B92 SAH 4.15225
162 3DMH SAM 4.15225
163 3DMH GMP 4.15225
164 5AZC PGT 4.15225
165 2X24 X24 4.15225
166 5WP4 SAH 4.15225
167 5OVL NAP 4.15225
168 2ZSC BTN 4.25532
169 4NBW NAD 4.28016
170 1FK8 NAD 4.28016
171 5ICK FEZ 4.36681
172 5N5D SAM 4.42478
173 2VDV SAM 4.47154
174 5BW4 SAM 4.49438
175 4C4A SAH 4.49827
176 2UYQ SAM 4.49827
177 5FA5 MTA 4.49827
178 4UCI SAM 4.49827
179 4GQB 0XU 4.49827
180 2YX1 SFG 4.49827
181 4DMG SAM 4.49827
182 1UOU CMU 4.49827
183 1XHL NDP 4.49827
184 5FWA J7C 4.49827
185 1XKQ NDP 4.49827
186 6B3A SAM 4.49827
187 3FZG SAM 4.5
188 3PCJ INO 4.5
189 6DUB SAH 4.5045
190 3RKR NAP 4.58015
191 5CIC 51R 4.62963
192 3SJU NDP 4.6595
193 5OVK NDP 4.6875
194 3KIF GDL 4.71698
195 6GFK SAH 4.78088
196 3Q87 SAM 4.8
197 4D3F NAP 4.83871
198 2JJQ SAH 4.84429
199 5ERG SAM 4.84429
200 3GXO SAH 4.84429
201 3GWZ SAH 4.84429
202 2Q28 ADP 4.84429
203 4Y30 SAH 4.84429
204 3L9W AMP 4.84429
205 3L9W GSH 4.84429
206 5JE0 SAH 4.8583
207 5JE0 AZ8 4.8583
208 2AG5 NAD 4.87805
209 3P2E SAH 4.88889
210 4CQM NAP 4.91803
211 4NV1 TYD 4.93827
212 3PFG TLO 4.94297
213 3PFG SAM 4.94297
214 1I9G SAM 5
215 4KRG SAH 5.19031
216 6GKV SAH 5.19031
217 4LWP SAH 5.19031
218 4N49 SAM 5.19031
219 5E72 SAM 5.19031
220 3TDC 0EU 5.19031
221 3FW9 SLX 5.19031
222 1ZGS XMM 5.19031
223 2B4Q NAP 5.19031
224 4Z28 BTN 5.22388
225 6BR7 BEF 5.26316
226 4C1K PEP 5.34351
227 2BGM NAJ 5.39568
228 3C3Y SAH 5.48523
229 4FN4 NAD 5.51181
230 5X62 SAH 5.53633
231 1RJD SAM 5.53633
232 5F2K SAH 5.53633
233 5F2K OCA 5.53633
234 3HQ9 OXL 5.53633
235 4BLW SAH 5.53633
236 3W54 RNB 5.53633
237 3QWI NAP 5.55556
238 5M58 SAH 5.65217
239 2JAH NDP 5.66802
240 2JAP NDP 5.66802
241 5XLX SAH 5.67376
242 5ZW3 SAH 5.77778
243 2GJ3 FAD 5.83333
244 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 5.85774
245 5W7K SAH 5.88235
246 5E9W SAH 5.88235
247 2AOT SAH 5.88235
248 3LJU IP9 5.88235
249 4M51 BEZ 5.88235
250 3WMX NAD 5.88235
251 4XUC SAM 5.9633
252 4XUC 43G 5.9633
253 4TV1 36M 5.9761
254 6HDT BTN 6.01504
255 4JNJ BTN 6.08696
256 1Q0S SAH 6.17761
257 2QRD ADP 6.18557
258 6ECT SAM 6.22837
259 5CKS GAL 6.22837
260 5JJR SAH 6.22837
261 5MPT SAH 6.22837
262 2UW1 GVM 6.22837
263 5A6B OAN 6.22837
264 5W7M SAH 6.22837
265 6EL3 NAP 6.22837
266 1VL0 NAI 6.22837
267 3MB5 SAM 6.27451
268 3T7S SAM 6.34328
269 5DM1 SAH 6.36704
270 5DM1 5D7 6.36704
271 5DLY SAH 6.39098
272 5DLY 5D7 6.39098
273 4C2W ANP 6.45161
274 2Z77 HE7 6.47482
275 4YAC NAI 6.57439
276 3I53 SAH 6.57439
277 2IZ1 ATR 6.57439
278 4M37 SAH 6.57439
279 4M38 SAH 6.57439
280 5MB4 NDG 6.57439
281 2OEM 1AE 6.57439
282 1F3L SAH 6.57439
283 6D6Y SAH 6.57439
284 2BIF BOG 6.57439
285 1KYZ SAH 6.57439
286 4J1Q NDP 6.57439
287 5FTW SAH 6.64062
288 5UFN SAH 6.72269
289 5E8J SAH 6.81818
290 3GUZ PAF 6.81818
291 2EFJ SAH 6.92042
292 3BGD SAH 6.92042
293 4O1M NAD 6.92042
294 3A27 SAM 6.92042
295 3BGD PM6 6.92042
296 1EJ0 SAM 7.22222
297 1E5Q NDP 7.26644
298 2XYQ SAH 7.37705
299 1R18 SAH 7.48899
300 4POO SAM 7.5
301 5YEC ATP 7.56302
302 5GM1 SAH 7.61246
303 3VSE SAH 7.61246
304 4A6D SAM 7.61246
305 1R6B ADP 7.61246
306 5JGL SAM 7.61246
307 3TN7 NJP 7.61246
308 5EEH SAH 7.61246
309 5EEH P9P 7.61246
310 3CW9 AMP 7.61246
311 1O5I NAD 7.63052
312 6CI9 NAP 7.72201
313 1YYE 196 7.83582
314 2NXE SAM 7.87402
315 3R1V AZB 7.87402
316 4AG9 COA 7.87879
317 3H2B SAH 7.88177
318 4FZV SAM 7.94979
319 2O07 MTA 7.95848
320 2O07 SPD 7.95848
321 4E70 N7I 7.95848
322 3A4T SFG 8.0292
323 2DPM SAM 8.09859
324 1Q7B NAP 8.19672
325 3I7V ATP 8.20895
326 1WY7 SAH 8.21256
327 5THZ SAH 8.3045
328 1XDS SAM 8.3045
329 1QZZ SAM 8.3045
330 5THY SAH 8.3045
331 1NW5 SAM 8.3045
332 5HCN DAO 8.3045
333 4Q9N NAI 8.3045
334 5W7B MYR 8.51064
335 4OBW SAM 8.56031
336 5CUQ NSC 8.61423
337 2BZG SAH 8.62069
338 5WP5 SAH 8.65052
339 2ZIF SAM 8.65052
340 1V59 NAD 8.65052
341 2WA2 SAM 8.69565
342 1U3R 338 8.71369
343 3N8K D1X 8.72093
344 4R6W PC 8.91473
345 4R6W SAH 8.91473
346 3PT9 SAH 8.99654
347 2JHP SAH 8.99654
348 4B6C B5U 9.18367
349 4KYK IMN 9.23913
350 2PX8 SAH 9.29368
351 3NUG NAD 9.34256
352 5Z2L NDP 9.38776
353 1P77 ATR 9.55882
354 4IWN GEK 9.60699
355 2IF8 ADP 9.68858
356 1X87 NAD 9.68858
357 2ZWA SAH 9.68858
358 5TVI O8N 9.78261
359 5GWX SAM 9.85915
360 5GWX SAR 9.85915
361 5L95 AMP 10
362 4AZW SAM 10.0346
363 1JG3 ADN 10.2128
364 1AE1 NAP 10.2564
365 6C4N NAP 10.7266
366 3GU3 SAH 11.0727
367 3H5N ATP 11.0727
368 4ONQ SFG 11.4187
369 2CE7 ADP 11.4187
370 2XVM SAH 11.5578
371 2PXX SAH 11.6279
372 3TKA SAM 11.7647
373 4N14 WR7 11.7647
374 5IL1 SAM 11.7647
375 4QTU SAM 11.8519
376 1WG8 SAM 11.9298
377 1N2X SAM 12.1107
378 1IM8 SAI 12.2951
379 4O0L NDP 12.3636
380 3JWH SAH 12.4424
381 3QOX SAH 13.1488
382 5MW4 5JU 13.1488
383 1Z3C SA8 13.4948
384 1NFQ NAI 13.4948
385 5HJM MTA 13.8408
386 5ICE SAH 13.8408
387 5ICE 2H4 13.8408
388 4KRI SAH 14.1869
389 6F5Z SAH 14.5329
390 3OFK SAH 14.8148
391 1UZN NAP 14.9798
392 2EG5 SAH 15.2249
393 2EJU SAH 15.2249
394 2HMT NAI 15.2778
395 5FA8 SAM 16.7702
396 1NE6 SP1 17.3145
397 1L3I SAH 18.75
398 4PNE SAH 21.7993
399 2ZFU SAH 21.8605
400 1XCL SAH 22.1277
401 5YF1 SFG 22.1453
402 5YF1 8V0 22.1453
403 5E1M SAH 23.6515
404 5E1M PRO PRO LYS ARG ILE ALA 23.6515
405 1P1C SAH 26.1307
406 4OGQ 7PH 29.0323
Pocket No.: 3; Query (leader) PDB : 2OBF; Ligand: SAH; Similar sites found with APoc: 36
This union binding pocket(no: 3) in the query (biounit: 2obf.bio3) has 43 residues
No: Leader PDB Ligand Sequence Similarity
1 3I7S PYR 1.38408
2 5LOG SAH 1.71674
3 4PBG BGP 1.7301
4 4PO2 ASN ARG LEU LEU LEU THR GLY 2.12766
5 5ME4 HP4 2.18978
6 1SWG BTN 2.34375
7 4TQ3 GPP 2.42215
8 3JQQ A2P 2.42215
9 2Q1A 2KT 2.76817
10 4UX9 ANP 2.76817
11 1V8B NAD 2.76817
12 2GNM MAN 2.77778
13 3E7S AT2 3.11419
14 2DE4 BPS 3.11419
15 3OJO NAD 3.11419
16 2PT9 S4M 3.11419
17 5CK5 GDP 3.16456
18 4RQL SNE 3.46021
19 1V08 NTZ 3.46021
20 3JQ7 NAP 3.47222
21 1NC4 DOF 3.61991
22 1VBO MAN MAN MAN 4.02685
23 2HYQ MAN MAN 4.09836
24 2BMB PMM 4.15225
25 5V6F MAN BMA MAN 4.34783
26 3FSY SCA 4.84429
27 5GG9 8GM 4.84429
28 5U83 ZN8 5.18868
29 6BQ6 TER 5.53633
30 1GEE NAD 5.74713
31 4JIE BMA 6.22837
32 1VBJ CIT 6.57439
33 1VAY AZA 7.31707
34 2PK3 A2R 7.61246
35 2O5L MNR 8.49673
36 1ZEI CRS 16.9811
Pocket No.: 4; Query (leader) PDB : 2OBF; Ligand: F83; Similar sites found with APoc: 45
This union binding pocket(no: 4) in the query (biounit: 2obf.bio3) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 3LHS SF8 1.03806
2 3I7S PYR 1.38408
3 5G3R 89A 1.7301
4 2JK0 ASP 2.07612
5 5OCM NAP 2.07612
6 3AI3 SOE