Receptor
PDB id Resolution Class Description Source Keywords
2f34 1.74 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE GLUR5 LIGAND BINDING CORE DIMER WIT AT 1.74 ANGSTROMS RESOLUTION RATTUS NORVEGICUS MEMBRANE PROTEIN
Ref.: CRYSTAL STRUCTURES OF THE KAINATE RECEPTOR GLUR5 LI BINDING CORE DIMER WITH NOVEL GLUR5-SELECTIVE ANTAG J.NEUROSCI. V. 26 2852 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data Chemaxon Viewer Molecular Weight (Da) Formula SMILES
1PE A:602;
B:601;
Invalid;
Invalid;
none;
none;
submit data 238.278 C10 H22 O6 C(COC...
CL A:501;
B:502;
Invalid;
Invalid;
none;
none;
submit data 35.453 Cl [Cl-]
UBA A:801;
B:802;
Valid;
Valid;
none;
none;
Kd = 0.13 uM 353.35 C14 H15 N3 O6 S CC1=C...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3FV1 1.5 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF THE HUMAN GLUTAMATE RECEPTOR, GLUR5, LI BINDING CORE IN COMPLEX WITH DYSIHERBAINE IN SPACE GROUP P1 HOMO SAPIENS NATURAL COMPOUND GLUTAMATE RECEPTOR LIGAND MEMBRANE PROTE
Ref.: BINDING AND SELECTIVITY OF THE MARINE TOXIN NEODYSI A AND ITS SYNTHETIC ANALOGUES TO GLUK1 AND GLUK2 KA RECEPTORS. J.MOL.BIOL. V. 413 667 2011
Members (31)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 201 families.
1 1TXF Ki = 57.2 nM GLU C5 H9 N O4 O=C([O-])C....
2 3GBB Ki = 126 nM MS8 C11 H17 N O6 C1C[C@@H]2....
3 2QS3 Kd = 1.4 nM UBE C20 H19 N3 O6 S CC1=CN(C(=....
4 2OJT - UBA C14 H15 N3 O6 S CC1=CN(C(=....
5 3C33 - KAI C10 H15 N O4 CC(=C)[C@H....
6 2WKY Ki = 2.57 nM IBC C11 H14 N2 O4 C1CC=C(c2c....
7 2PBW Ki = 5.56 nM DOQ C15 H21 N O6 C[C@H](C=C....
8 3FVG Ki = 128 nM MS8 C11 H17 N O6 C1C[C@@H]2....
9 3C36 - KAI C10 H15 N O4 CC(=C)[C@H....
10 2F34 Kd = 0.13 uM UBA C14 H15 N3 O6 S CC1=CN(C(=....
11 3C32 - KAI C10 H15 N O4 CC(=C)[C@H....
12 2QS2 Kd = 186 nM UBF C13 H12 Br N3 O6 S c1csc(c1CN....
13 3FVN Ki = 169 nM 9DX C11 H17 N O7 C1CO[C@@H]....
14 1YCJ - GLU C5 H9 N O4 O=C([O-])C....
15 4DLD Ki = 1.5 uM TZG C12 H13 Cl N2 O6 c1c(c(cc(c....
16 3FVK Ki = 1.5 nM 8DX C11 H17 N O7 C1[C@@H](C....
17 2ZNU Ki = 7.7 nM NDZ C11 H17 N O8 C1[C@@H]2[....
18 3S2V Ki = 157 nM 3HU C15 H13 N3 O6 S2 c1csc(c1CN....
19 3C35 - KAI C10 H15 N O4 CC(=C)[C@H....
20 3C31 - KAI C10 H15 N O4 CC(=C)[C@H....
21 3FV1 Ki = 0.5 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
22 2QS1 Kd = 33 nM UB1 C14 H13 Br2 N3 O6 S CC1=CN(C(=....
23 4E0X - KAI C10 H15 N O4 CC(=C)[C@H....
24 3C34 - KAI C10 H15 N O4 CC(=C)[C@H....
25 2F36 - GLU C5 H9 N O4 O=C([O-])C....
26 2ZNT Ki = 0.5 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
27 2F35 Kd = 3.94 uM UBC C15 H15 N3 O6 c1ccc(c(c1....
28 3GBA Ki = 0.848 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
29 3FV2 Ki = 7.7 nM NDZ C11 H17 N O8 C1[C@@H]2[....
30 1VSO Ki = 18980 nM AT1 C11 H19 N2 O7 P CC(C)(C)c1....
31 2QS4 Kd = 38 nM LY5 C16 H24 F2 N2 O4 C1C[C@H]2C....