Receptor
PDB id Resolution Class Description Source Keywords
2evm 1.7 Å EC: 3.4.11.18 CRYSTAL STRUCTURE OF METHIONINE AMINOPEPTIDASE IN COMPLEX WITH 5-(2,5-DICHLOROPHENYL)FURAN-2-CARBOXYLIC ACID ESCHERICHIA COLI METHIONINE AMINOPEPTIDASE COMPLEX HYDROLASE
Ref.: STRUCTURAL ANALYSIS OF METALLOFORM-SELECTIVE INHIBITION OF METHIONINE AMINOPEPTIDASE. ACTA CRYSTALLOGR.,SECT.D V. 62 425 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FC2 A:999;
 Valid;
 none;
 ic50 = 0.693 uM
257.07 C11 H6 Cl2 O3 c1cc(...
MN A:901;
A:902;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
54.938 Mn [Mn+2...
NA A:903;
 Part of Protein;
 none;
 submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YVM 1.6 Å EC: 3.4.11.18 E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH THIABENDAZOLE ESCHERICHIA COLI HYDROLASE(ALPHA-AMINOACYLPEPTIDE) METAL COMPLEX THIABENDAZOLE METHIONINE AMINOPEPTIDASE INHIBITOR
Ref.: METAL IONS AS COFACTORS FOR THE BINDING OF INHIBITORS TO METHIONINE AMINOPEPTIDASE: A CRITICAL VIEW OF THE RELEVANCE OF IN VITRO METALLOENZYME ASSAYS. ANGEW.CHEM.INT.ED.ENGL. V. 44 3620 2005
Members (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
70% Homology Family (36)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
2 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
3 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
4 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
5 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
6 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
7 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
8 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
9 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
10 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
11 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
12 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
13 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
14 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
15 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
16 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
17 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
18 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
19 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
20 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
21 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
22 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
23 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
24 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
25 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
26 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
27 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
28 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
29 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
30 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
31 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
32 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
33 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
34 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
35 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
36 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
50% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2NQ6 ic50 = 1.5 uM HM4 C14 H16 N4 O3 S CC(C)(C)OC....
2 4U69 Ki = 54.8 uM Q07 C6 H16 N O3 P CCC[C@H](C....
3 2G6P ic50 = 0.6 uM HM2 C18 H17 Cl N4 Cc1c(c(nc(....
4 4U73 Ki = 6.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
5 4IKT ic50 = 0.67 uM TFV C18 H16 Cl F3 N6 Cc1c(c(nc(....
6 4U6Z Ki = 3.9 uM Q07 C6 H16 N O3 P CCC[C@H](C....
7 4U70 Ki = 9.5 uM Q04 C8 H18 N O3 P C1CCC(CC1)....
8 4FLI ic50 = 3.59 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
9 4U6C Ki = 9.9 uM Q06 C8 H18 N O3 P C1CCC(C1)C....
10 4IKR ic50 = 0.59 uM PVP C16 H20 Cl N5 O Cc1c(c(nc(....
11 4FLK ic50 = 5.58 uM Y10 C21 H31 N O5 CC(C)(C)/C....
12 4IKU ic50 = 1.79 uM SHX C19 H18 Cl N5 O Cc1c(c(nc(....
13 2NQ7 ic50 = 2.9 uM HM5 C14 H16 N4 O2 S CC(C)(C)C(....
14 4FLL ic50 = 5.14 uM YZ6 C25 H35 N O6 CC(C)(C)/C....
15 4U71 Ki = 6 uM Q03 C7 H16 N O3 P C1CCC(CC1)....
16 4HXX - 1AY C28 H29 Cl2 N5 Cc1c(c(nc(....
17 4IKS ic50 = 7.23 uM TFD C18 H16 Cl F3 N6 Cc1c(c(nc(....
18 4U6E Ki = 111.6 uM Q02 C7 H10 N O3 P c1ccc(cc1)....
19 4U1B Ki = 4.9 uM Q08 C8 H20 N O3 P CCCC(CCC)[....
20 4FLJ ic50 = 7.45 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
21 2GG0 ic50 = 1.7 uM U11 C16 H20 F3 N3 O5 C[C@@H](C(....
22 1YVM Ki = 0.4 uM TMG C10 H7 N3 S c1ccc2c(c1....
23 2GU6 - NLP C5 H14 N O3 P CCCC[C@H](....
24 2Q95 ic50 = 1.6 uM A05 C11 H6 Cl N O5 c1cc(c(cc1....
25 2GG8 ic50 = 25 uM U15 C20 H31 N3 O5 Cc1ccc(cc1....
26 2GTX - NLP C5 H14 N O3 P CCCC[C@H](....
27 2EVC ic50 = 0.29 uM FC3 C12 H7 F3 O3 c1ccc(c(c1....
28 4A6W ic50 = 1.9 uM 5C1 C10 H7 Cl N2 O3 c1ccc(c(c1....
29 2GG3 ic50 = 0.58 uM U13 C9 H7 F N6 [H]/N=C/1C....
30 3D27 ic50 = 55.7 uM W29 C12 H12 O2 S CCc1ccsc1c....
31 2GG7 ic50 = 1.75 uM U14 C10 H8 N6 O2 [H]/N=C1/C....
32 2GU5 - NLP C5 H14 N O3 P CCCC[C@H](....
33 1XNZ ic50 = 0.24 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
34 4A6V ic50 = 1.9 uM IKY C11 H7 F3 N2 O3 c1ccc(c(c1....
35 1C21 - MET C5 H11 N O2 S CSCC[C@@H]....
36 2Q92 ic50 = 1.1 uM B23 C11 H7 N O5 c1ccc(c(c1....
37 1C27 - NLP C5 H14 N O3 P CCCC[C@H](....
38 1C24 - MPJ C4 H12 N O2 P S CSCC[C@H](....
39 2EVO ic50 = 0.067 uM CT0 C10 H13 N3 O2 S c1csc(n1)N....
40 2P99 ic50 = 1.16 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
41 2GG9 ic50 = 3.5 uM U16 C22 H35 N3 O5 CC(C)C[C@H....
42 2Q94 ic50 = 0.37 uM A04 C12 H7 F3 O4 c1ccc(c(c1....
43 2P98 ic50 = 0.64 uM YE7 C12 H10 N4 O c1ccc2c(c1....
44 2GGB ic50 = 12 uM U17 C17 H33 N3 O6 CCCC[C@H](....
45 2EVM ic50 = 0.693 uM FC2 C11 H6 Cl2 O3 c1cc(c(cc1....
46 1C22 - MF3 C5 H8 F3 N O2 S C(CSC(F)(F....
47 1C23 - MPH C4 H12 N O3 P S CSCC[C@H](....
48 2Q96 ic50 = 1.2 uM A18 C12 H9 Cl O3 c1ccc(c(c1....
49 2BB7 ic50 = 2.14 uM QMS C10 H10 N2 O2 S CS(=O)(=O)....
50 2GG2 ic50 = 0.25 uM U12 C10 H7 F3 N6 c1cc(cc(c1....
51 2GGC - MET C5 H11 N O2 S CSCC[C@@H]....
52 2GU4 - NLP C5 H14 N O3 P CCCC[C@H](....
53 2Q93 ic50 = 0.56 uM B21 C12 H10 O4 COc1ccccc1....
54 2GG5 ic50 = 0.25 uM U19 C10 H7 F3 N6 [H]/N=C1/C....
55 3MAT - AHH ALA LEU VAL 0A9 n/a n/a
56 2P9A ic50 = 6.56 uM YE6 C11 H9 Cl N2 O2 c1ccc(c(c1....
57 4IU6 - FZ1 C24 H23 N5 O COc1ccc(cc....
58 1QXZ ic50 = 19 uM M3C C8 H14 N2 O2 S2 CSCC[C@@H]....
59 1QXY ic50 = 16 uM M2C C10 H16 N2 O2 S CSCC[C@@H]....
60 1QXW ic50 = 7 uM M1C C10 H22 N2 O2 CCCC[C@@H]....
61 3IU9 ic50 = 0.24 uM T07 C9 H8 Cl2 N4 S c1cc(c(cc1....
62 3IU7 ic50 = 16 uM FCD C11 H7 Cl O3 c1ccc(c(c1....
63 3PKE - Y10 C21 H31 N O5 CC(C)(C)/C....
64 3PKB ic50 = 0.62 uM Y16 C14 H26 N2 O6 CC(C)(C)/C....
65 3PKA ic50 = 0.54 uM Y02 C23 H37 N O6 Cc1cc(c(c(....
66 3PKC ic50 = 0.96 uM Y08 C22 H38 N2 O6 CC(C)(C)/C....
67 3IU8 ic50 = 0.58 uM T03 C9 H8 F N3 S c1cc(ccc1C....
68 3PKD ic50 = 0.76 uM Y10 C21 H31 N O5 CC(C)(C)/C....
69 1YJ3 - MET C5 H11 N O2 S CSCC[C@@H]....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: FC2; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 FC2 1 1
2 FCD 0.529412 1
Similar Ligands (3D)
Ligand no: 1; Ligand: FC2; Similar ligands found: 436
No: Ligand Similarity coefficient
1 M83 0.9626
2 B21 0.9621
3 AUV 0.9589
4 TJM 0.9548
5 L5D 0.9496
6 1XS 0.9486
7 Q4G 0.9479
8 IQQ 0.9476
9 YE6 0.9473
10 PQT 0.9470
11 TIZ 0.9466
12 G14 0.9442
13 WVV 0.9436
14 EAJ 0.9419
15 4ZF 0.9416
16 B23 0.9406
17 4G2 0.9404
18 XEV 0.9396
19 TCR 0.9373
20 TI7 0.9368
21 ZZA 0.9355
22 3VQ 0.9333
23 5C1 0.9317
24 ELH 0.9314
25 5VU 0.9286
26 AMR 0.9284
27 6MW 0.9275
28 1ER 0.9270
29 5F8 0.9269
30 GZV 0.9266
31 MD6 0.9265
32 QKU 0.9264
33 II4 0.9259
34 QIV 0.9237
35 DXK 0.9228
36 78Y 0.9223
37 KCH 0.9221
38 6HO 0.9214
39 1SF 0.9210
40 0FR 0.9202
41 D9Z 0.9198
42 1AJ 0.9191
43 0LO 0.9183
44 Q9T 0.9178
45 ODK 0.9174
46 LL1 0.9170
47 4FF 0.9169
48 5FL 0.9163
49 2LW 0.9163
50 2UD 0.9158
51 4AU 0.9148
52 L22 0.9148
53 7ZL 0.9141
54 JMG 0.9137
55 KLE 0.9131
56 AV4 0.9131
57 RUG 0.9128
58 4V2 0.9128
59 8D6 0.9127
60 HRM 0.9125
61 5B2 0.9118
62 Q2S 0.9115
63 PZ8 0.9113
64 DTR 0.9110
65 F40 0.9110
66 9FH 0.9110
67 FER 0.9110
68 VAO 0.9109
69 BXZ 0.9102
70 6FB 0.9095
71 7G2 0.9091
72 L1T 0.9090
73 PUE 0.9085
74 BIO 0.9085
75 JWS 0.9078
76 5AE 0.9075
77 K48 0.9067
78 ADN 0.9067
79 28B 0.9066
80 EQA 0.9061
81 774 0.9060
82 YE7 0.9057
83 LFQ 0.9057
84 D3G 0.9056
85 TIA 0.9054
86 A9B 0.9050
87 ZME 0.9048
88 IDZ 0.9047
89 XI7 0.9047
90 1A7 0.9045
91 URI 0.9044
92 PIQ 0.9041
93 2GD 0.9040
94 0K7 0.9039
95 C0H 0.9038
96 S1D 0.9032
97 JSX 0.9031
98 VBC 0.9030
99 5F5 0.9029
100 1KN 0.9029
101 KMY 0.9029
102 H4E 0.9023
103 D8Q 0.9020
104 4Z1 0.9011
105 795 0.9010
106 0UL 0.9008
107 0NX 0.9007
108 EAT 0.9005
109 5NN 0.9004
110 9JT 0.9004
111 2QV 0.9004
112 BBY 0.9001
113 TOH 0.9000
114 8CC 0.8999
115 BIK 0.8999
116 5AD 0.8999
117 BSV 0.8998
118 KWB 0.8997
119 A5H 0.8990
120 LR2 0.8989
121 RGK 0.8989
122 NE2 0.8986
123 DT7 0.8983
124 CBE 0.8983
125 CK2 0.8983
126 4GU 0.8974
127 M4N 0.8973
128 TRP 0.8973
129 5E5 0.8972
130 HBI 0.8971
131 30G 0.8970
132 LZ5 0.8970
133 RBV 0.8970
134 TB8 0.8969
135 KYN 0.8967
136 2QU 0.8964
137 833 0.8961
138 9CE 0.8960
139 X29 0.8959
140 MR6 0.8959
141 SU9 0.8958
142 G30 0.8956
143 EWG 0.8955
144 3D8 0.8955
145 K7H 0.8953
146 U13 0.8952
147 7MX 0.8950
148 NFZ 0.8950
149 2D2 0.8949
150 0SY 0.8948
151 ZRK 0.8948
152 6J5 0.8945
153 ITE 0.8944
154 THM 0.8943
155 272 0.8943
156 4Z3 0.8942
157 5TZ 0.8940
158 363 0.8938
159 X48 0.8938
160 C0W 0.8938
161 3XH 0.8937
162 W29 0.8933
163 CK1 0.8933
164 5WK 0.8932
165 JF5 0.8931
166 ZEA 0.8929
167 H35 0.8928
168 E9S 0.8925
169 JGB 0.8925
170 27M 0.8924
171 Y3L 0.8921
172 VM1 0.8920
173 5P3 0.8920
174 GXG 0.8920
175 BP7 0.8916
176 KW7 0.8914
177 3D1 0.8910
178 28A 0.8909
179 JCQ 0.8908
180 JFS 0.8907
181 5H6 0.8901
182 D1G 0.8899
183 B2T 0.8897
184 9UL 0.8896
185 ZRL 0.8896
186 GZ2 0.8893
187 HA6 0.8893
188 7O4 0.8891
189 79W 0.8890
190 9FG 0.8887
191 5ER 0.8884
192 0DF 0.8883
193 GO8 0.8882
194 WOE 0.8879
195 NIR 0.8879
196 1ZC 0.8877
197 SQV 0.8877
198 WLH 0.8876
199 JF8 0.8876
200 AVA 0.8876
201 IOP 0.8874
202 H4B 0.8874
203 5V7 0.8871
204 F18 0.8871
205 ZYW 0.8868
206 B1J 0.8868
207 OA1 0.8867
208 CX6 0.8867
209 WCU 0.8866
210 1FL 0.8863
211 MUX 0.8861
212 CHQ 0.8859
213 55D 0.8858
214 ZHA 0.8855
215 NK5 0.8853
216 P4T 0.8852
217 5GV 0.8850
218 A73 0.8849
219 P4L 0.8849
220 LI7 0.8849
221 XDK 0.8847
222 5WT 0.8847
223 FHV 0.8846
224 20D 0.8845
225 BPY 0.8844
226 3RP 0.8842
227 BZE 0.8839
228 LJ4 0.8839
229 VM7 0.8837
230 92G 0.8837
231 FHI 0.8837
232 Q5M 0.8836
233 4EU 0.8834
234 X6P 0.8834
235 A7Q 0.8832
236 MIL 0.8832
237 1QP 0.8828
238 D1Y 0.8827
239 47V 0.8827
240 0RY 0.8825
241 TVC 0.8824
242 BQ2 0.8824
243 FC3 0.8824
244 5GT 0.8822
245 EFX 0.8821
246 PZX 0.8820
247 Q92 0.8819
248 KWV 0.8818
249 4HB 0.8818
250 4CN 0.8817
251 S8G 0.8815
252 R9G 0.8814
253 LJ3 0.8814
254 A6W 0.8814
255 EYJ 0.8813
256 GJK 0.8813
257 C53 0.8812
258 3TC 0.8812
259 DFL 0.8811
260 CSN 0.8810
261 M01 0.8810
262 L03 0.8807
263 B2E 0.8806
264 D2G 0.8805
265 DUR 0.8805
266 3GX 0.8804
267 AVX 0.8803
268 MR4 0.8798
269 C09 0.8796
270 RA7 0.8796
271 IKY 0.8792
272 ARJ 0.8788
273 NOC 0.8788
274 X11 0.8787
275 FMQ 0.8786
276 ZYQ 0.8785
277 M3W 0.8784
278 OX2 0.8783
279 NIY 0.8783
280 78U 0.8782
281 8UY 0.8781
282 C4E 0.8778
283 TCC 0.8778
284 XG1 0.8776
285 6C9 0.8775
286 ISC 0.8773
287 N9J 0.8767
288 HBO 0.8765
289 ERZ 0.8765
290 EQW 0.8762
291 6C8 0.8762
292 UN9 0.8762
293 NNR 0.8760
294 CTN 0.8760
295 YZM 0.8759
296 5WN 0.8759
297 IMK 0.8757
298 FZM 0.8757
299 25F 0.8757
300 AV7 0.8755
301 SOV 0.8753
302 SJK 0.8753
303 S8D 0.8752
304 B4O 0.8751
305 A18 0.8750
306 6C5 0.8750
307 FCW 0.8749
308 M02 0.8747
309 9BF 0.8747
310 GNW 0.8747
311 IXM 0.8745
312 AZC 0.8741
313 MEX 0.8741
314 PBQ 0.8740
315 MXD 0.8740
316 HX4 0.8739
317 0QV 0.8737
318 2P3 0.8736
319 MZR 0.8735
320 KLS 0.8730
321 MTA 0.8730
322 LEL 0.8729
323 OSB 0.8728
324 C9M 0.8725
325 3Q0 0.8722
326 4XF 0.8722
327 6L6 0.8722
328 372 0.8721
329 0ON 0.8719
330 J38 0.8718
331 61M 0.8717
332 RKV 0.8716
333 DHC 0.8716
334 AJ1 0.8715
335 U4J 0.8714
336 PYU 0.8713
337 QME 0.8713
338 H70 0.8713
339 V2Z 0.8712
340 P93 0.8708
341 7L4 0.8706
342 6J9 0.8704
343 PCQ 0.8703
344 KLV 0.8699
345 26C 0.8698
346 DBS 0.8698
347 68B 0.8698
348 6C4 0.8696
349 SOJ 0.8696
350 38E 0.8693
351 6QT 0.8692
352 C9E 0.8685
353 5SJ 0.8683
354 MR5 0.8683
355 A4G 0.8682
356 I5A 0.8681
357 VT3 0.8680
358 MQS 0.8678
359 4FP 0.8677
360 U7E 0.8676
361 2JX 0.8675
362 KP2 0.8675
363 2TU 0.8674
364 GXD 0.8671
365 4Z9 0.8670
366 DCZ 0.8670
367 6DQ 0.8665
368 28S 0.8662
369 6H2 0.8659
370 CIY 0.8658
371 0OY 0.8658
372 7FZ 0.8658
373 D80 0.8658
374 7EH 0.8658
375 6FG 0.8657
376 49P 0.8656
377 LAH 0.8655
378 0XR 0.8655
379 3F4 0.8655
380 1HP 0.8655
381 C0Y 0.8653
382 CTD 0.8652
383 90G 0.8647
384 SZ5 0.8644
385 ZIP 0.8644
386 CX4 0.8639
387 108 0.8636
388 WV7 0.8635
389 7MW 0.8635
390 5TO 0.8634
391 HH6 0.8632
392 X6W 0.8631
393 37E 0.8631
394 A05 0.8630
395 T28 0.8629
396 MFR 0.8626
397 BRY 0.8626
398 XYP XIF 0.8621
399 9XZ 0.8620
400 RVE 0.8620
401 CC6 0.8616
402 DDC 0.8612
403 BVS 0.8612
404 NE1 0.8610
405 RSV 0.8609
406 78P 0.8606
407 JTF 0.8606
408 ONR 0.8604
409 CC5 0.8604
410 P83 0.8603
411 G1P 0.8603
412 FY8 0.8603
413 JGY 0.8600
414 92O 0.8600
415 DBE 0.8597
416 SQ4 0.8596
417 NPG 0.8594
418 XIF XYP 0.8592
419 LTN 0.8591
420 BDI 0.8580
421 6JO 0.8573
422 PE2 0.8570
423 57D 0.8570
424 36M 0.8568
425 LVD 0.8562
426 XDL XYP 0.8559
427 AOY 0.8554
428 22L 0.8553
429 M3E 0.8552
430 PQM 0.8552
431 ML1 0.8550
432 ATX 0.8540
433 JAH 0.8538
434 RK4 0.8525
435 1Z6 0.8522
436 4AB 0.8515
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YVM; Ligand: TMG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 1yvm.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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