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Receptor
PDB id Resolution Class Description Source Keywords
2bla 2.5 Å EC: 1.5.1.3 SP21 DOUBLE MUTANT P. VIVAX DIHYDROFOLATE REDUCTASE IN COMPL PYRIMETHAMINE PLASMODIUM VIVAX DIHYDROFOLATE REDUCTASE PLASMODIUM VIVAX PYRIMETHAMINE MADRUG RESISTANCE OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF DIHYDROFOLATE REDUCTASE FROM P VIVAX: PYRIMETHAMINE DISPLACEMENT LINKED WITH MUTATION-INDUCED RESISTANCE. PROC.NATL.ACAD.SCI.USA V. 102 13046 2005
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CP6 A:1240;
Valid;
none;
Ki = 50 nM
248.711 C12 H13 Cl N4 CCc1c...
MES A:1241;
Invalid;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
NDP A:1239;
Valid;
none;
submit data
745.421 C21 H30 N7 O17 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2BL9 1.9 Å EC: 1.5.1.3 X-RAY CRYSTAL STRUCTURE OF PLASMODIUM VIVAX DIHYDROFOLATE REDUCTASE IN COMPLEX WITH PYRIMETHAMINE AND ITS DERIVATIVE PLASMODIUM VIVAX DIHYDROFOLATE REDUCTASE PLAMODIUM VIVAX PYRIMETHAMINE MALARIA DRUG RESISTANCE OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF DIHYDROFOLATE REDUCTASE FROM PLASMODIUM VIVAX: PYRIMETHAMINE DISPLACEMENT LINKED WITH MUTATION-INDUCED RESISTANCE. PROC.NATL.ACAD.SCI.USA V. 102 13046 2005
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 28 families.
1 2BLC Ki = 7.3 nM CP7 C12 H14 N4 CCc1c(c(nc....
2 2BL9 Ki = 0.16 nM CP6 C12 H13 Cl N4 CCc1c(c(nc....
3 2BLA Ki = 50 nM CP6 C12 H13 Cl N4 CCc1c(c(nc....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 22 families.
1 2BLC Ki = 7.3 nM CP7 C12 H14 N4 CCc1c(c(nc....
2 2BL9 Ki = 0.16 nM CP6 C12 H13 Cl N4 CCc1c(c(nc....
3 2BLA Ki = 50 nM CP6 C12 H13 Cl N4 CCc1c(c(nc....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 2BLC Ki = 7.3 nM CP7 C12 H14 N4 CCc1c(c(nc....
2 2BL9 Ki = 0.16 nM CP6 C12 H13 Cl N4 CCc1c(c(nc....
3 2BLA Ki = 50 nM CP6 C12 H13 Cl N4 CCc1c(c(nc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: CP6; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 CP6 1 1
2 CP7 0.625 0.904762
3 7IG 0.484848 0.891304
Ligand no: 2; Ligand: NDP; Similar ligands found: 172
No: Ligand ECFP6 Tc MDL keys Tc
1 NDP 1 1
2 0WD 0.827273 1
3 NAI 0.803738 0.986842
4 NMN AMP PO4 0.794643 0.948052
5 NPW 0.692308 0.962025
6 NZQ 0.686441 0.987013
7 1DG 0.68 1
8 DG1 0.68 1
9 A2R 0.650943 0.909091
10 A22 0.64486 0.934211
11 TXP 0.644628 0.924051
12 ATR 0.640777 0.894737
13 NA7 0.636364 0.886076
14 XNP 0.620968 0.949367
15 AP0 0.598361 0.948718
16 A2P 0.598039 0.881579
17 NJP 0.574803 0.923077
18 25L 0.550847 0.934211
19 ODP 0.550388 0.936709
20 NAX 0.544 0.949367
21 25A 0.53913 0.921053
22 80F 0.537879 0.914634
23 2AM 0.529412 0.87013
24 6V0 0.519685 0.974026
25 NAP 0.514493 0.922078
26 7L1 0.507143 0.763441
27 EAD 0.507143 0.949367
28 A2D 0.504673 0.921053
29 TXE 0.503876 0.935897
30 NA0 0.496454 0.910256
31 TXD 0.496124 0.911392
32 SAP 0.495575 0.875
33 AGS 0.495575 0.875
34 P1H 0.493056 0.925926
35 CO7 0.489796 0.791209
36 TAP 0.489362 0.864198
37 PAP 0.482456 0.907895
38 BA3 0.481818 0.921053
39 NAJ PZO 0.478261 0.924051
40 ATP 0.477876 0.921053
41 HEJ 0.477876 0.921053
42 B4P 0.477477 0.921053
43 AP5 0.477477 0.921053
44 ADP 0.477477 0.921053
45 OAD 0.47541 0.897436
46 AR6 0.473684 0.896104
47 AQP 0.473684 0.921053
48 5FA 0.473684 0.921053
49 APR 0.473684 0.896104
50 AN2 0.473214 0.909091
51 3OD 0.467742 0.897436
52 50T 0.464912 0.884615
53 NAJ PYZ 0.464789 0.879518
54 9X8 0.463415 0.851852
55 PO4 PO4 A A A A PO4 0.463415 0.857143
56 V3L 0.461538 0.896104
57 2A5 0.46087 0.85
58 AT4 0.460177 0.886076
59 A1R 0.459016 0.841463
60 4AD 0.459016 0.875
61 ADQ 0.459016 0.897436
62 OVE 0.458716 0.8375
63 OMR 0.458647 0.813953
64 PPS 0.457627 0.811765
65 AD9 0.456897 0.897436
66 CA0 0.45614 0.897436
67 M33 0.45614 0.884615
68 ADJ 0.455882 0.879518
69 A3P 0.455357 0.894737
70 ACP 0.452174 0.897436
71 ENP 0.451613 0.85
72 UP5 0.451128 0.948052
73 SRP 0.45 0.8625
74 ANP 0.449153 0.897436
75 ACQ 0.449153 0.897436
76 PRX 0.448276 0.82716
77 A3R 0.447154 0.841463
78 5AL 0.445378 0.884615
79 7D4 0.443478 0.8375
80 ADX 0.443478 0.811765
81 6YZ 0.438017 0.897436
82 A 0.436364 0.894737
83 AMP 0.436364 0.894737
84 4TC 0.433824 0.924051
85 7D3 0.433628 0.8375
86 DCA 0.433566 0.788889
87 ETB 0.433566 0.797753
88 BIS 0.433071 0.864198
89 1ZZ 0.433071 0.802326
90 00A 0.432 0.864198
91 ATF 0.429752 0.886076
92 DQV 0.428571 0.934211
93 0T1 0.427586 0.788889
94 5SV 0.427419 0.788235
95 8QN 0.427419 0.884615
96 3AM 0.427273 0.857143
97 N01 0.426573 0.884615
98 PR8 0.425197 0.811765
99 LAD 0.425197 0.821429
100 WAQ 0.425197 0.841463
101 DTP 0.425 0.8375
102 AMO 0.424 0.886076
103 PAJ 0.424 0.843373
104 APC 0.423729 0.886076
105 UPA 0.423358 0.935897
106 48N 0.422222 0.853659
107 FYA 0.421875 0.860759
108 PTJ 0.421875 0.853659
109 CNA 0.421429 0.910256
110 PUA 0.42069 0.9125
111 DND 0.419118 0.910256
112 NXX 0.419118 0.910256
113 AV2 0.418033 0.848101
114 COA 0.417808 0.788889
115 3UK 0.417323 0.897436
116 OOB 0.416 0.909091
117 IVC 0.415584 0.78022
118 DAT 0.415254 0.8375
119 NDO 0.414966 0.897436
120 139 0.414286 0.901235
121 B5V 0.414062 0.886076
122 T99 0.413223 0.886076
123 TAT 0.413223 0.886076
124 3AT 0.413223 0.896104
125 YLB 0.413043 0.784091
126 62F 0.4125 0.823529
127 ABM 0.412281 0.848101
128 B5M 0.412214 0.875
129 YAP 0.412214 0.875
130 YLP 0.411765 0.784091
131 NB8 0.410853 0.853659
132 ME8 0.410853 0.802326
133 SON 0.410256 0.886076
134 DLL 0.409449 0.909091
135 AHX 0.409449 0.853659
136 CAO 0.409396 0.763441
137 30N 0.409396 0.72449
138 AMX 0.409396 0.797753
139 COS 0.409396 0.771739
140 7D5 0.409091 0.8125
141 4UW 0.408759 0.9125
142 F2R 0.408451 0.825581
143 APX 0.407692 0.841463
144 SRA 0.40708 0.85
145 CMX 0.406667 0.788889
146 SCO 0.406667 0.788889
147 TYM 0.405797 0.886076
148 COD 0.405594 0.777778
149 CA6 0.405229 0.70297
150 OXK 0.405229 0.771739
151 AP2 0.405172 0.886076
152 A12 0.405172 0.886076
153 9SN 0.40458 0.853659
154 LAQ 0.404412 0.802326
155 T5A 0.404255 0.914634
156 FAM 0.403974 0.771739
157 ACO 0.403974 0.763441
158 FCX 0.403974 0.763441
159 VO4 ADP 0.403226 0.860759
160 ADP VO4 0.403226 0.860759
161 YLC 0.402878 0.823529
162 1VU 0.402597 0.763441
163 B5Y 0.401515 0.875
164 FA5 0.401515 0.886076
165 HAX 0.401316 0.771739
166 AR6 AR6 0.4 0.871795
167 CAJ 0.4 0.771739
168 AFH 0.4 0.843373
169 APU 0.4 0.923077
170 A U 0.4 0.898734
171 TXA 0.4 0.886076
172 4UU 0.4 0.948052
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2BL9; Ligand: NDP; Similar sites found with APoc: 208
This union binding pocket(no: 1) in the query (biounit: 2bl9.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 3KPE TM3 None
2 2D2F ADP 0.840336
3 5A96 GTP 1.2605
4 2RDE C2E 1.2605
5 3KCC CMP 1.2605
6 5HWK BEZ 1.2605
7 1AX2 NDG GAL 1.2605
8 4WAS COO 1.2605
9 3B6C SDN 1.28205
10 3KYG 5GP 5GP 1.32159
11 3GD8 GOL 1.34529
12 1NF8 BOG 1.44928
13 1G6H ADP 1.68067
14 6BE0 COA 1.68067
15 4L9Z OXL 1.68067
16 1NXJ TLA 1.68067
17 1NPD NAD 1.68067
18 3CBG SAH 1.72414
19 4WZ6 ATP 2.10084
20 3B8I OXL 2.10084
21 2IYA UDP 2.10084
22 2IYF UDP 2.10084
23 5T96 79J 2.10084
24 1NJJ ORX 2.10084
25 3VGL ANP 2.10084
26 2RI1 GLP 2.12766
27 2PZE ATP 2.18341
28 4UTW RFW 2.18341
29 4NTO 1PW 2.41546
30 2J0B UDP 2.52101
31 2ACV UDP 2.52101
32 5HV7 RBL 2.52101
33 4XFR CIT 2.52101
34 3KC1 2T6 2.52101
35 6EOA FMN 2.52101
36 6F5W KG1 2.52101
37 2NUN ADP 2.52101
38 4OH4 ANP 2.52101
39 6EGU 43Y 2.52101
40 4OUC 5ID 2.52101
41 2JK0 ASP 2.52101
42 5M0T AKG 2.52101
43 1VMK GUN 2.52708
44 3M2W L8I 2.94118
45 5LY1 PPI 2.94118
46 4PPF FLC 2.94118
47 3HWW AKG 2.94118
48 3TDC 0EU 2.94118
49 5BWD FUM 2.94118
50 1QPR PHT 2.94118
51 3NHB ADP 2.94118
52 2WIC GNP 2.94118
53 1NST A3P 2.94118
54 4JAL SAH 2.99401
55 1UXX XYP XYP XYP XYP XYP 3.00752
56 3KYF 5GP 5GP 3.0303
57 5BXV MGP 3.125
58 2FFU UDP 3.19361
59 1MVN FMN 3.34928
60 5AHO TLA 3.36134
61 3B6O TMP 3.36134
62 4RUS NAG 3.36134
63 2Q8M AMP 3.36134
64 1NLM UD1 3.36134
65 5FPE 3TR 3.36134
66 2WOE AR6 3.36134
67 1SKQ GDP 3.36134
68 2CBZ ATP 3.37553
69 1JJV ATP 3.39806
70 1LK7 DER 3.49345
71 5YRM BGC GLC 3.52113
72 4DW4 U5P 3.59281
73 4OOP DUP 3.61446
74 5FQK 6NT 3.71747
75 3EYK EYK 3.78151
76 2OG2 MLI 3.78151
77 4YJ1 ADP 3.78151
78 1PIG BGC 3.78151
79 4RL4 PPV 3.78151
80 2HZL PYR 3.78151
81 1BYG STU 3.78151
82 2CDU ADP 3.78151
83 2XAU ADP 3.78151
84 1PFK ADP 3.78151
85 4ONQ SFG 3.78151
86 1H5S TMP 3.78151
87 3LM9 ADP 3.78151
88 4R2I ANP 3.80952
89 2VOH CIT 3.82166
90 2JKG PRO PRO PRO PRO PRO PRO PRO PRO 3.91061
91 3ITJ CIT 4.20168
92 5KJW 53C 4.20168
93 1YQT ADP 4.20168
94 5GLN XYP XYP XYP 4.20168
95 2YVK MRU 4.20168
96 5TC4 NAD 4.20168
97 5YRG BGC GLC 4.22535
98 5YRJ BGC GLC 4.22535
99 5I8F ML1 4.24242
100 2FT0 ACO 4.25532
101 4DD8 BAT 4.32692
102 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 4.62185
103 4WBD CIT 4.62185
104 1RJW ETF 4.62185
105 5WHU SIA GAL 4.62185
106 3B5J 12D 4.62185
107 5YV5 ADP 4.62185
108 2HHP FLC 4.62185
109 5YEE LAB 4.62185
110 5G1X ADP 4.7619
111 3P48 DUP 4.7619
112 5ZZA LAB 4.95868
113 2AWN ADP 5.04202
114 1JJ7 ADP 5.04202
115 5W6Y TRP 5.04202
116 2X1E X1E 5.04202
117 5Y0T TAT 5.04202
118 1UJ5 5RP 5.28634
119 4RT1 C2E 5.35714
120 5AJU RP5 5.46218
121 4HE2 AMP 5.46218
122 2J5V PCA 5.46218
123 5F7J ADE 5.46218
124 6G33 5ID 5.46218
125 3HBF UDP 5.46218
126 3NOJ PYR 5.46218
127 4IDT T28 5.46218
128 3FIU POP 5.62249
129 1B4B ARG 5.6338
130 4HA9 NDP 5.88235
131 4WOV 3SM 5.88235
132 5CX6 CDP 5.88235
133 2ZJ5 ADP 5.88235
134 2RIO ADP 5.88235
135 3RK0 AMP 5.90717
136 4UEC MGT 5.97826
137 2UZH IPE 6.06061
138 2QV7 ADP 6.30252
139 5XHA FRU 6.30252
140 4G2R H1L 6.30252
141 2OFE NAG 6.33803
142 4UCC ZKW 6.43777
143 2BS5 BGC GAL FUC 6.66667
144 5NM7 GLY 6.72269
145 1T9D P22 6.72269
146 5B0I BOG 6.72269
147 5WKC TP9 6.72269
148 1J78 OLA 6.72269
149 4UP4 GAL NAG 6.72269
150 1VKF CIT 6.91489
151 2BO4 FLC 7.0529
152 5E5U MLI 7.14286
153 4B5W PYR 7.14286
154 1D8C GLV 7.56302
155 2CE7 ADP 7.56302
156 6BK3 UDP 7.98319
157 1TV5 N8E 7.98319
158 3K5I AIR 7.98319
159 1VBO MAN MAN MAN 8.05369
160 5LX9 OLB 8.09859
161 5URY PAM 8.21918
162 4LIK CIT 8.40336
163 2OBM ADP 8.40336
164 1JS8 MAN MAN BMA 8.40336
165 1Y4Z PCI 8.40336
166 4KVL PLM 8.82353
167 5IFK HPA 8.82353
168 3LRE ADP 8.82353
169 5ZBL AMP 8.82353
170 1ZJ6 G3D 8.82353
171 2A19 ANP 9.14286
172 5ZI9 FLC 9.2437
173 4XT8 TMQ 9.66387
174 4XT8 NAP 9.66387
175 1FWV SGA MAG FUC 9.70149
176 1M7G AV2 9.95261
177 3PNA CMP 10.3896
178 3I7S PYR 10.5042
179 3ZIA ADP 10.5042
180 3KDM TES 11.1111
181 4X1T UDP 11.3445
182 3KP6 SAL 11.9205
183 4FRZ ADP 12.1849
184 3H4S ADP 12.1849
185 6CS8 F9Y 12.605
186 5Y4R C2E 13.1034
187 1Q19 SSC 13.4454
188 2V7Q ADP 13.4454
189 4G86 BNT 13.8655
190 5XLY C2E 14.2857
191 5A7Y SAH 14.2857
192 1HBK COA 14.6067
193 4BGB ADP 14.7059
194 2W58 ADP 14.8515
195 1WZ1 DNS 15.0442
196 5A07 GDP 15.126
197 3KO0 TFP 17.8218
198 5FJJ MAN 18.0672
199 3GFS FMN 20.6897
200 2Y69 CHD 28.866
201 5DXV NAP 31.4103
202 5ZCO CHD 32.9412
203 5Z84 CHD 32.9412
204 5W97 CHD 32.9412
205 3NRR NAP 42.437
206 3NRR D16 42.437
207 4EIL NDP 44.5378
208 4EIL FOL 44.5378
Pocket No.: 2; Query (leader) PDB : 2BL9; Ligand: CP6; Similar sites found with APoc: 185
This union binding pocket(no: 2) in the query (biounit: 2bl9.bio1) has 36 residues
No: Leader PDB Ligand Sequence Similarity
1 3KPE TM3 None
2 2D2F ADP 0.840336
3 5A96 GTP 1.2605
4 2RDE C2E 1.2605
5 3KCC CMP 1.2605
6 5HWK BEZ 1.2605
7 1AX2 NDG GAL 1.2605
8 4WAS COO 1.2605
9 3KYG 5GP 5GP 1.32159
10 3GD8 GOL 1.34529
11 1NF8 BOG 1.44928
12 4L9Z OXL 1.68067
13 6BE0 COA 1.68067
14 1NXJ TLA 1.68067
15 2IYF UDP 2.10084
16 4WZ6 ATP 2.10084
17 3B8I OXL 2.10084
18 2IYA UDP 2.10084
19 5T96 79J 2.10084
20 1NJJ ORX 2.10084
21 2VWT PYR 2.10084
22 2RI1 GLP 2.12766
23 2PZE ATP 2.18341
24 4UTW RFW 2.18341
25 4NTO 1PW 2.41546
26 2J0B UDP 2.52101
27 5HV7 RBL 2.52101
28 4XFR CIT 2.52101
29 2ACV UDP 2.52101
30 3KC1 2T6 2.52101
31 6F5W KG1 2.52101
32 4DDY DN6 2.52101
33 1YBH P22 2.52101
34 2NUN ADP 2.52101
35 4DE3 DN8 2.52101
36 6EGU 43Y 2.52101
37 4OUC 5ID 2.52101
38 4OH4 ANP 2.52101
39 2JK0 ASP 2.52101
40 5M0T AKG 2.52101
41 3VYW SAM 2.52101
42 1VMK GUN 2.52708
43 1XX6 ADP 2.6178
44 4PPF FLC 2.94118
45 3TDC 0EU 2.94118
46 3HWW AKG 2.94118
47 5XQL C2E 2.94118
48 5BWD FUM 2.94118
49 1QPR PHT 2.94118
50 3NHB ADP 2.94118
51 3W5J GDP 2.94118
52 2WIC GNP 2.94118
53 1NST A3P 2.94118
54 1UXX XYP XYP XYP XYP XYP 3.00752
55 3KYF 5GP 5GP 3.0303
56 1YNS HPO 3.06513
57 5BXV MGP 3.125
58 2FFU UDP 3.19361
59 5AHO TLA 3.36134
60 1M2Z BOG 3.36134
61 3B6O TMP 3.36134
62 4RUS NAG 3.36134
63 1NLM UD1 3.36134
64 5FPE 3TR 3.36134
65 2WOE AR6 3.36134
66 1SKQ GDP 3.36134
67 2CBZ ATP 3.37553
68 1JJV ATP 3.39806
69 1LK7 DER 3.49345
70 5C8W PCG 3.4965
71 4OOP DUP 3.61446
72 5FQK 6NT 3.71747
73 4YJ1 ADP 3.78151
74 1PIG BGC 3.78151
75 4RL4 PPV 3.78151
76 5AZC PGT 3.78151
77 1BYG STU 3.78151
78 2HZL PYR 3.78151
79 2ZV2 609 3.78151
80 2XAU ADP 3.78151
81 4R2I ANP 3.80952
82 2VOH CIT 3.82166
83 2JKG PRO PRO PRO PRO PRO PRO PRO PRO 3.91061
84 5KJW 53C 4.20168
85 3ITJ CIT 4.20168
86 1YQT ADP 4.20168
87 5GLN XYP XYP XYP 4.20168
88 2YVK MRU 4.20168
89 2FT0 ACO 4.25532
90 4DD8 BAT 4.32692
91 2YVJ NAI 4.58716
92 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 4.62185
93 1RJW ETF 4.62185
94 4WBD CIT 4.62185
95 3B5J 12D 4.62185
96 5WHU SIA GAL 4.62185
97 5YV5 ADP 4.62185
98 5YEE LAB 4.62185
99 5G1X ADP 4.7619
100 3P48 DUP 4.7619
101 5ZZA LAB 4.95868
102 2AWN ADP 5.04202
103 1JJ7 ADP 5.04202
104 5W6Y TRP 5.04202
105 2X1E X1E 5.04202
106 5Y0T TAT 5.04202
107 4RT1 C2E 5.35714
108 2J5V PCA 5.46218
109 5F7J ADE 5.46218
110 6G33 5ID 5.46218
111 4HE2 AMP 5.46218
112 3HBF UDP 5.46218
113 3NOJ PYR 5.46218
114 5AJU RP5 5.46218
115 4IDT T28 5.46218
116 3FIU POP 5.62249
117 1B4B ARG 5.6338
118 4HA9 NDP 5.88235
119 4WOV 3SM 5.88235
120 5CX6 CDP 5.88235
121 3DRW AMP 5.88235
122 3RK0 AMP 5.90717
123 2QV7 ADP 6.30252
124 5XHA FRU 6.30252
125 4G2R H1L 6.30252
126 4UCC ZKW 6.43777
127 2BS5 BGC GAL FUC 6.66667
128 5NM7 GLY 6.72269
129 1T9D P22 6.72269
130 5B0I BOG 6.72269
131 5WKC TP9 6.72269
132 1J78 OLA 6.72269
133 4UP4 GAL NAG 6.72269
134 1VKF CIT 6.91489
135 2BO4 FLC 7.0529
136 5E5U MLI 7.14286
137 4B5W PYR 7.14286
138 1D8C GLV 7.56302
139 2CE7 ADP 7.56302
140 4WNP 3RJ 7.98319
141 5LX9 OLB 8.09859
142 5URY PAM 8.21918
143 4LIK CIT 8.40336
144 2OBM ADP 8.40336
145 1JS8 MAN MAN BMA 8.40336
146 4KVL PLM 8.82353
147 5ZBL AMP 8.82353
148 5IFK HPA 8.82353
149 3LRE ADP 8.82353
150 1ZJ6 G3D 8.82353
151 2A19 ANP 9.14286
152 5ZI9 FLC 9.2437
153 4XT8 TMQ 9.66387
154 4XT8 NAP 9.66387
155 1FWV SGA MAG FUC 9.70149
156 1M7G AV2 9.95261
157 3PNA CMP 10.3896
158 3I7S PYR 10.5042
159 3ZIA ADP 10.5042
160 3KDM TES 11.1111
161 1WDI CIT 11.3445
162 4X1T UDP 11.3445
163 3H4S ADP 12.1849
164 6CS8 F9Y 12.605
165 5Y4R C2E 13.1034
166 1Q19 SSC 13.4454
167 2V7Q ADP 13.4454
168 4G86 BNT 13.8655
169 1WRA PC 13.8655
170 1HBK COA 14.6067
171 2W58 ADP 14.8515
172 1WZ1 DNS 15.0442
173 5A07 GDP 15.126
174 3KO0 TFP 17.8218
175 5FJJ MAN 18.0672
176 3GFS FMN 20.6897
177 2Y69 CHD 28.866
178 5DXV NAP 31.4103
179 5ZCO CHD 32.9412
180 5Z84 CHD 32.9412
181 5W97 CHD 32.9412
182 3NRR NAP 42.437
183 3NRR D16 42.437
184 4EIL NDP 44.5378
185 4EIL FOL 44.5378
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